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Tuberculosis imaging

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https://www.readbyqxmd.com/read/29347976/intracisternal-tuberculoma-a-refractory-type-of-tuberculoma-indicating-surgical-intervention
#1
Fanfan Chen, Lei Chen, Yongfu Cao, Yongjun Yi, Jingwen Zhuang, Wuhua Le, Wei Xie, Lanbo Tu, Peng Li, Yimin Fang, Ling Li, Yuqing Kou, Kaikai Fu, Hua He, Hongbin Ju
BACKGROUND: Central nervous system (CNS) tuberculoma is a rare disease with severe neurological deficits. This retrospective research is to review the data of patients diagnosed as CNS tuberculoma. Surgeries were performed in all patients. The clinical features especially the neurological image and the anatomical characters of the tuberculomas were concerned. METHODS: Totally 11 patients diagnosed as CNS tuberculoma were admitted in Guangzhou First People's Hospital (7cases) and Changzheng Hospital (4 cases) during 2006-2015...
January 18, 2018: BMC Neurology
https://www.readbyqxmd.com/read/29340585/spinal-tuberculosis-clinicoradiological-findings-in-274-patients
#2
Suzaan Marais, Izanne Roos, Ayesha Mitha, Sepelong J Mabusha, Vinod Patel, Ahmed I Bhigjee
Background: Mycobacterium tuberculosis is a major cause of myelopathy and radiculopathy in high TB/HIV prevalent settings. However, a paucity of publications exists on the spectrum of neurological and magnetic resonance imaging (MRI) findings of spinal tuberculosis in these populations. Methods: A retrospective study of adults with spinal tuberculosis conducted at a referral center for patients with spinal disease without bony involvement on plain film radiography in South Africa...
January 11, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29332658/an-extremely-rare-association-of-sweet-s-syndrome-with-active-pulmonary-tuberculosis
#3
Sandhya Chauhan
Sweet's syndrome is a skin manifestation of various systemic infections, drugs, malignancies and autoimmune disorders. There are very few case reports describing the relationship between Sweet's syndrome and non-tubercular mycobacterium infection. Further development of Sweet's syndrome secondary to mycobacterium tuberculosis (active pulmonary tuberculosis) is extremely uncommon and this is the second well established case reported from India. Here we report a forty eight year old man who presented with multiple erythematous and tender plaques over neck, palms and sides of soles...
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29326867/cavitary-lung-lesion-suspicious-for-malignancy-reveals-mycobacterium-xenopi
#4
Sumit Fogla, Vaishali M Pansare, Luis G Camero, Uzma Syeda, Naveen Patil, Arun Chaudhury
We report the case of a 68-year-old gentleman who presented with musculoskeletal chest pain which appeared suddenly when he bent over with his dog. The chest pain was localized to the left lower chest and increased with movement and deep breathing. The patient did not complain weight loss, night sweat, fever or chill. He complained of mild cough, with expectoration of whitish mucus. Imaging revealed cavitary chest lesion in the right upper lobe, which was initially suspected to be lung cancer. The patient had a 50-year-old history of smoking 2 packs per day...
2018: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/29325545/phthiocerol-dimycocerosates-promote-access-to-the-cytosol-and-intracellular-burden-of-mycobacterium-tuberculosis-in-lymphatic-endothelial-cells
#5
Thomas R Lerner, Christophe J Queval, Antony Fearns, Urska Repnik, Gareth Griffiths, Maximiliano G Gutierrez
BACKGROUND: Phthiocerol dimycocerosates (PDIM), glycolipids found on the outer surface of virulent members of the Mycobacterium tuberculosis (Mtb) complex, are a major contributing factor to the pathogenesis of Mtb. Myelocytic cells, such as macrophages and dendritic cells, are the primary hosts for Mtb after infection and previous studies have shown multiple roles for PDIM in supporting Mtb in these cells. However, Mtb can infect other cell types. We previously showed that Mtb efficiently replicates in human lymphatic endothelial cells (hLECs) and that the hLEC cytosol acts as a reservoir for Mtb in humans...
January 4, 2018: BMC Biology
https://www.readbyqxmd.com/read/29273829/isolated-subcutaneous-nontuberculous-mycobacterial-infection-a-rare-case-initially-mischaracterized-as-a-soft-tissue-malignancy
#6
Hee Young Choi, Min Hee Lee, Jong-Seok Lee, In Hye Song, Kyung-Ja Cho
The occurrence of nontuberculous mycobacterial (NTM) infection is rare, and the involvement of the musculoskeletal system is even less common. However, the incidence of soft tissue and skin NTM infection is increasing, particularly in patients who undergo injections and minor surgical procedures. Given the non-specific clinical manifestations of NTM infection, the lack of knowledge among physicians regarding this rare infection could lead to inaccurate and delayed diagnosis. Herein, we present a case of an isolated subcutaneous NTM infection caused by Mycobacterium abscessus in the upper back of an immunocompetent 68-year-old woman...
December 22, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/29251339/-extramedullary-intradural-tuberculosis-a-case-report-and-review-of-the-literature
#7
D Quispe, M Alvarado, D Rivas, I Gonzales
INTRODUCTION: Central nervous system tuberculosis is a common chronic infection in developing countries, being the most frequent forms: tuberculous meningitis and intracranial tuberculosis. Extramedullary intradural tuberculosis is a rare entity with few cases described in the world literature, and is usually associated with a history of tuberculous meningitis or during antituberculosis treatment. CASE REPORT: A 17 years-old male patient, without history of tuberculosis, with subacute onset and progressive course of compressive myelopathy...
January 1, 2018: Revista de Neurologia
https://www.readbyqxmd.com/read/29251272/endoscopic-ultrasound-guided-fine-needle-aspiration-from-ascites-and-peritoneal-nodules-a-scoping-review
#8
REVIEW
Vishal Sharma, Surinder Singh Rana, Sobur Uddin Ahmed, Sonali Guleria, Ravi Sharma, Rajesh Gupta
The peritoneum is involved in many diseases such as primary malignancy (mesothelioma), infectious disease (tuberculosis), and disseminated malignancy (peritoneal carcinomatosis). The peritoneal disease may manifest as ascites and/or peritoneal masses or nodules. Endoscopic ultrasound (EUS), due to its ability to provide high-resolution images, has revolutionized the imaging and diagnosis of pancreaticobiliary diseases among other gastrointestinal conditions. EUS can not only help in imaging of various lesions close to the gastrointestinal lumen but also aspirate/biopsy them...
November 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/29245227/spinal-intramedullary-tuberculoma-following-pulmonary-tuberculosis-a-case-report-and-literature-review
#9
Guan-Chyuan Wang, Sheng-Wen Wu
RATIONALE: Spinal intramedullary tuberculoma (IMTB) is a rare disease that accounts for 1 to 2/100,000 patients with tuberculosis. We presented a case with pulmonary tuberculosis and concurrent IMTB at C3 to C5 level and reviewed the recent case series and discussed the diagnosis, treatment, and outcome. PATIENT CONCERNS: A 33-year-old male had concurrent pulmonary TB and IMTB at the C3 to C5 level. He had quadriplegia (muscle power 0 at 4 limbs) and sensory loss below C5 level...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29239241/tuberculous-spondylitis-after-vertebral-augmentation-a-case-report-with-a-literature-review
#10
Sun Jia-Jia, Sun Zhi-Yong, Qian Zhong-Lai, Yang Hui-Lin, Zhu Xiao-Yu
Tuberculous spondylitis of vertebral augmentation following percutaneous vertebroplasty or kyphoplasty is rare. We report an unusual case of tuberculous spondylitis diagnosed after percutaneous kyphoplasty (PKP). A 54-year-old woman presented to hospital complaining of back pain following a fall 20 days prior. Radiology showed an acute osteoporotic compression (L3 fracture). The patient denied a history of pulmonary tuberculosis and there were no signs of infection. The patient was discharged from hospital 2 days after undergoing L3 PKP with a dramatic improvement in her back pain...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/29232189/a-rare-cause-of-hypophysitis-tuberculosis
#11
Ihsan Ates, B Katipoglu, B Copur, N Yilmaz
OBJECTIVES: Hypophysitis is a heterogeneous inflammatory disease of pituitary gland. As it causes headache and visual defects, it mimics sellar tumors in clinical and radiological aspects. It may occur due to primary or secondary causes. Tuberculosis is one of the rare secondary causes of the hypophysitis. Subject and Results. A 30-year-old male patient presented with fatigue and headache. Panhypopituitarism was considered due to the results and the diagnostic magnetic resonance (MR) imaging revealed sagittal section diamater of pituitary gland higher than normal...
October 26, 2017: Endocrine Regulations
https://www.readbyqxmd.com/read/29228529/efficacy-of-bronchial-washing-and-brushing-cytology-in-the-diagnosis-of-non-neoplastic-lung-diseases
#12
Rahil Giti, Massood Hosseinzadeh
Flexible fiberoptic bronchoscopy is often the initial technique for diagnosis of lung and bronchial tumors. Many studies have shown the high accuracy rate of bronchial washing and brushing cytology in the evaluation of neoplastic and non-neoplastic bronchopulmonary lesions. The aim of this study is to emphasize the value of the bronchial cytologic findings for diagnosis of non-neoplastic bronchopulmonary lesions. In a cross-sectional study, we retrieved all cases with bronchial washing and brushing cytology from 21 Mach 2014 to 21 December 2015...
October 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/29225379/tailoring-trehalose-for-biomedical-and-biotechnological-applications
#13
Mara K O'Neill, Brent F Piligian, Claire D Olson, Peter J Woodruff, Benjamin M Swarts
Trehalose is a non-reducing sugar whose ability to stabilize biomolecules has brought about its widespread use in biological preservation applications. Trehalose is also an essential metabolite in a number of pathogens, most significantly the global pathogen Mycobacterium tuberculosis, though it is absent in humans and other mammals. Recently, there has been a surge of interest in modifying the structure of trehalose to generate analogues that have applications in biomedical research and biotechnology. Non-degradable trehalose analogues could have a number of advantages as bioprotectants and food additives...
September 2017: Pure and Applied Chemistry. Chimie Pure et Appliquée
https://www.readbyqxmd.com/read/29210092/comparison-of-digital-and-film-chest-radiography-for-detection-and-medical-surveillance-of-silicosis-in-a-setting-with-a-high-burden-of-tuberculosis
#14
Alfred Franzblau, Jim teWaterNaude, Ananda Sen, Hannah d'Arcy, Jacqueline S Smilg, Khanyakude S Mashao, Cristopher A Meyer, James E Lockey, Rodney I Ehrlich
BACKGROUND: Continuing use of analog film and digital chest radiography for screening and surveillance for pneumoconiosis and tuberculosis in lower and middle income countries raises questions of equivalence of disease detection. This study compared analog to digital images for intra-rater agreement across formats and prevalence of changes related to silicosis and tuberculosis among South African gold miners using the International Labour Organization classification system. METHODS: Miners with diverse radiological presentations of silicosis and tuberculosis were recruited...
December 6, 2017: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/29209953/diagnostic-value-of-99mtc-ethambutol-scintigraphy-in-tuberculosis-compared-to-microbiological-and-histopathological-tests
#15
A H S Kartamihardja, Y Kurniawati, R Gunawan
OBJECTIVE: Tuberculosis (TB) still remains the world's endemic infection. TB affects the lungs and any part of the body other than the lung. The diagnosis of TB has not changed much over the decades. Ethambutol is one of the first line treatments for TB. It can be labeled using 99mTc. 99mTc-ethambutol will be accumulated in the site of TB lesion and can be imaged using gamma camera. The aim of this study was to evaluate the diagnostic value of 99mTc-ethambutol scintigraphy in detecting and localizing of TB...
December 5, 2017: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29207771/aspects-of-evolving-genito-urinary-tuberculosis-a-profile-of-genito-urinary-tuberculosis-gutb-in-110-patients
#16
Sriram Krishnamoorthy, Velmurugan Palaniyandi, Natarajan Kumaresan, Sivasankar Govindaraju, Jayaganesh Rajasekaran, Ilangovan Murugappan, Venkat Ramanan, Muthulatha Navaneetha Krishnan
Introduction: Genito Urinary Tuberculosis (GUTB) is a widespread disease seen in urology practice. The true incidence and prevalence of GUTB is difficult to estimate because a large number of patients remain asymptomatic. Aim: To recognize typical and atypical clinical and radiological features of tuberculosis and to emphasize the need for diagnosing GUTB early. Materials and Methods: This was a retrospective study conducted in 110 cases of GUTB diagnosed and treated in two teaching institutions over a period of three years, from July 2002 to June 2005...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29207463/synthesis-and-characterization-of-polyaniline-graphene-composite-nanofiber-and-its-application-as-an-electrochemical-dna-biosensor-for-the-detection-of-mycobacterium-tuberculosis
#17
Fatimah Syahidah Mohamad, Mohd Hazani Mat Zaid, Jaafar Abdullah, Ruzniza Mohd Zawawi, Hong Ngee Lim, Yusran Sulaiman, Norizah Abdul Rahman
This article describes chemically modified polyaniline and graphene (PANI/GP) composite nanofibers prepared by self-assembly process using oxidative polymerization of aniline monomer and graphene in the presence of a solution containing poly(methyl vinyl ether-alt-maleic acid) (PMVEA). Characterization of the composite nanofibers was carried out by Fourier transform infrared (FTIR) and Raman spectroscopy, transmission electron microscopy (TEM) and scanning electron microscopy (SEM). SEM images revealed the size of the PANI nanofibers ranged from 90 to 360 nm in diameter and was greatly influenced by the proportion of PMVEA and graphene...
December 2, 2017: Sensors
https://www.readbyqxmd.com/read/29205485/combination-of-increased-visceral-fat-and-long-segment-involvement-development-and-validation-of-an-updated-imaging-marker-for-differentiating-crohn-s-disease-from-intestinal-tuberculosis
#18
Saurabh Kedia, K S Madhusudhan, Raju Sharma, Sawan Bopanna, Dawesh P Yadav, Sandeep Goyal, Saransh Jain, Prasenjit Das, Siddhartha Dattagupta, Govind Makharia, Vineet Ahuja
BACKGROUND: Computed tomographic(CT) features(long segment, ileocaecal area involvement and lymph nodes>1cm) have demonstrated good specificity but poor sensitivity, while visceral to subcutaneous fat ratio on CT(VF/SC>0.63) has moderate sensitivity and specificity in differentiating Crohn's disease(CD) and intestinal tuberculosis(ITB). AIM: To develop and validate an updated model incorporating CT features and VF/SC to improve the diagnostic accuracy of imaging in differentiating CD/ITB...
December 4, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29199704/solitary-pulmonary-nodule-evaluation-in-regions-endemic-for-infectious-diseases-do-regional-variations-impact-the-effectiveness-of-fluorodeoxyglucose-positron-emission-tomography-computed-tomography
#19
N C Purandare, C S Pramesh, J P Agarwal, A Agrawal, S Shah, K Prabhash, G Karimundackal, S Jiwnani, S Tandon, V Rangarajan
BACKGROUND: Fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) has become a preferred imaging modality for the evaluation of solitary pulmonary nodule (SPN), particularly in the developed world. Since FDG can concentrate in infective/inflammatory lesions, the diagnostic utility of FDG-PET can be questioned, particularly in regions endemic for infectious decisions. AIM: To evaluate the accuracy of FDG-PET/CT in evaluation of SPNs in a population endemic for infectious disease and to assess if regional variations have an impact on its effectiveness...
January 2017: Indian Journal of Cancer
https://www.readbyqxmd.com/read/29198911/xpert-mtb-rif-ultra-for-detection-of-mycobacterium-tuberculosis-and-rifampicin-resistance-a-prospective-multicentre-diagnostic-accuracy-study
#20
Susan E Dorman, Samuel G Schumacher, David Alland, Pamela Nabeta, Derek T Armstrong, Bonnie King, Sandra L Hall, Soumitesh Chakravorty, Daniela M Cirillo, Nestani Tukvadze, Nino Bablishvili, Wendy Stevens, Lesley Scott, Camilla Rodrigues, Mubin I Kazi, Moses Joloba, Lydia Nakiyingi, Mark P Nicol, Yonas Ghebrekristos, Irene Anyango, Wilfred Murithi, Reynaldo Dietze, Renata Lyrio Peres, Alena Skrahina, Vera Auchynka, Kamal Kishore Chopra, Mahmud Hanif, Xin Liu, Xing Yuan, Catharina C Boehme, Jerrold J Ellner, Claudia M Denkinger
BACKGROUND: The Xpert MTB/RIF assay is an automated molecular test that has improved the detection of tuberculosis and rifampicin resistance, but its sensitivity is inadequate in patients with paucibacillary disease or HIV. Xpert MTB/RIF Ultra (Xpert Ultra) was developed to overcome this limitation. We compared the diagnostic performance of Xpert Ultra with that of Xpert for detection of tuberculosis and rifampicin resistance. METHODS: In this prospective, multicentre, diagnostic accuracy study, we recruited adults with pulmonary tuberculosis symptoms presenting at primary health-care centres and hospitals in eight countries (South Africa, Uganda, Kenya, India, China, Georgia, Belarus, and Brazil)...
November 30, 2017: Lancet Infectious Diseases
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