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Tuberculosis imaging

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https://www.readbyqxmd.com/read/27902591/a-novel-indication-for-a-method-in-the-treatment-of-lumbar-tuberculosis-through-minimally-invasive-extreme-lateral-interbody-fusion-xlif-in-combination-with-percutaneous-pedicle-screws-fixation-in-an-elderly-patient-a-case-report
#1
Qiyou Wang, Yichun Xu, Ruiqiang Chen, Jianwen Dong, Bin Liu, Limin Rong
RATIONALE: To describe a novel indication for a method through minimally invasive extreme lateral interbody fusion (XLIF) in combination with percutaneous pedicle screwsfixation in the treatment of lumbar tuberculosis (TB) in an elderly patient, and its clinical efficacy and feasibility. Lumbar TB is a destructive form of TB. Antituberculous treatment should be started as early as possible. In some circumstances, however, surgical debridement with or without stabilization of the spine appears to be beneficial and may be recommended...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27888495/an-unusual-presentation-of-intraocular-tuberculosis-in-a-monocular-patient-clinicopathological-correlation
#2
Kanika Aggarwal, Aniruddha Agarwal, Shobha Sehgal, Suryaprakash Sharma, Nirbhai Singh, Kusum Sharma, Ramanuj Samanta, Alessandro Invernizzi, Aman Sharma, Vishali Gupta
BACKGROUND: Lack of uniform diagnostic criteria often poses a challenge in the diagnosis and management of tubercular uveitis. The index case describes an unusual presentation of tubercular panuveitis initially misdiagnosed as sympathetic ophthalmia, where the appropriate diagnosis was made using various imaging and laboratory investigations. RESULTS: A 52-year-old Indian woman underwent multimodal imaging, extensive clinical and laboratory work-up, and analysis of microbiological and histopathological specimens...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27878107/imaging-the-nadh-nad-homeostasis-for-understanding-the-metabolic-response-of-mycobacterium-to-physiologically-relevant-stresses
#3
Shabir A Bhat, Iram K Iqbal, Ashwani Kumar
The NADH:NAD(+) ratio is the primary indicator of the metabolic state of bacteria. NAD(H) homeostasis is critical for Mycobacterium tuberculosis (Mtb) survival and is thus considered an important drug target, but the spatio-temporal measurements of NAD(H) remain a challenge. Genetically encoded fluorescent biosensors of the NADH:NAD(+) ratios were recently described, paving the way for investigations of the metabolic state of pathogens during infection. Here we have adapted the genetically encoded biosensor Peredox for measurement of the metabolic state of Mtb in vitro and during infection of macrophage cells...
2016: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/27865222/endometrial-tuberculosis-simulating-an-ovarian-cancer-a-case-report
#4
Silvia Eleonora Di Giovanni, Teresa Margarida Cunha, Ana Luisa Duarte, Ines Alves
Female genital tuberculosis remains a major health problem in developing countries and is an important cause of infertility. As symptoms, laboratory data and physical findings are non-specific, its diagnosis can be difficult. We describe a case of a 39-year-old woman suffering from peri-umbilical pain and increased abdominal size for one year, anorexia, asthenia, weight loss, occasionally dysuria and dyspareunia, and four months amenorrhea. Laboratory data revealed cancer antigen 125 (CA-125) level of 132.3 U/mL, erythrocyte sedimentation rate of 42 mm/h, and gamma-globulins of 2...
June 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/27861333/isolated-neurosarcoidosis-mimicking-multifocal-meningiomas-a-diagnosis-pitfall-a-case-report
#5
Kun Wang, Xiaoying He, Wei Wang, Huanjiang Niu, Yirong Wang, Xiujun Cai, Shuxu Yang
INTRODUCTION: Neurosarcoidosis accounts for approximately 5% of the sarcoidosis, which develops exclusively in the nervous system and is always difficult to diagnose. We describe a rare case of isolated neurosarcoidosis mimicking as multifocal meningiomas. A 27-year-old male was admitted to our hospital with a history of unconsciousness and convulsion 1 month ago, which was suspected as a seizure. The results showed no abnormalities in complete blood count; serum electrolytes; erythrocyte sedimentation rate and ultrasonography of the liver, pancreas, spleen, kidney and parotid gland, and so on...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27853495/giant-omental-cyst-lymphangioma-mimicking-ascites-and-tuberculosis
#6
Asuman Nur Karhan, Tutku Soyer, Altan Gunes, Beril Talim, Ibrahim Karnak, Berna Oguz, Inci Nur Saltik Temizel
Omental and mesenteric cysts are both rare pathologies in children. Children who have omental cysts usually display symptoms of abdominal distension, with or without a palpable mass. The mass can simulate ascites on clinical observation, or tuberculosis on radiological images. The optimal treatment for this condition is complete resection. The presenting symptoms of abdominal distension and the simulation of septated ascites and abdominal tuberculosis are unusual. Reported cases in the literature usually display symptoms of abdominal distension, abdominal pain, painless mass or possible ascites...
July 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
https://www.readbyqxmd.com/read/27853338/primary-enterolith-in-a-patient-with-intestinal-tuberculosis-a-case-report
#7
Mohd Habib Raza, RafiulImad Finan, Sadik Akhtar, Manzoor Ahmad
Primary enterolithiasis is a rare surgical ailment. The underlying cause is intestinal stasis. Numerous anatomical and micro environmental factors such as enteritis, incarcerated hernia, malignancy, diverticula, blind loops, and enteroenterostomy predispose to clinically significant concretions. Enterolithiasis in tuberculosis can be due to the presence of strictures, intestinal bands, or interbowel/parietal adhesions, leading to intestinal stasis. Secondary enterolithiasis is generally caused by gallstones or renal stones migrating to the gastrointestinal tract due to fistula formation...
November 2016: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/27824002/clinical-manifestations-of-fibrosing-mediastinitis-in-chinese-patients
#8
Yan Hu, Jian-Xing Qiu, Ji-Ping Liao, Hong Zhang, Zhe Jin, Guang-Fa Wang
BACKGROUND: Fibrosing mediastinitis (FM) is a rare disease. FM is thought to be related to prior granulomatous mediastinal infection, such as histoplasmosis or tuberculosis. The majority of cases have been reported in endemic regions for histoplasmosis. The characteristics of cases of FM in China, where the prevalence of tuberculosis is high, have not been reported. We analyzed the clinical, imaging, and bronchoscopic features of Chinese patients with FM to promote awareness of this disease...
2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27815879/quantitative-spatiotemporal-analysis-of-phagosome-maturation-in-live-cells
#9
Laura Schnettger, Maximiliano G Gutierrez
Phagocytosis and phagosome maturation are central to the development of the innate and adaptive immune response. Phagosome maturation is a continuous and dynamic process that occurs rapidly. In this chapter, we describe fluorescence-based live cell imaging methods for the quantitative and temporal analysis of phagosome maturation of latex beads and M. tuberculosis as two phagocytic targets. We also describe two simple protocols for monitoring phagosome maturation: the use of the acidotropic probe LysoTracker and analyzing the recruitment of EGFP-tagged host proteins by phagosomes...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27811346/tuberculosis-of-gal-blader-mimicking-malignancy-a-case-report
#10
Divya Dahiya, Lileswar Kaman, Jayapal Rajendran, Mandeep Garg
A correct preoperative diagnosis of gall-bladder tuberculosis is exceptionally unusual in the absence of pathognomic features both on clinical presentation and on imaging. Herein we present a case of 50 year female who was operated with a provisional diagnosis of gall-bladder malignancy and was found to have tuberculosis of gall-bladder on histopathology.
October 1, 2016: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/27807553/a-rare-case-of-isolated-pancreatic-tuberculosis
#11
Daniel J Waintraub, Lionel S D'Souza, Emilio Madrigal, Manju Harshan, Gil I Ascunce
Pancreatic tuberculosis (TB) is a rare but important entity to consider when evaluating a pancreatic mass, especially in patients from endemic areas. Its clinical and radiologic features may mimic those of a pancreatic neoplasm, making it a difficult clinical diagnosis. We present a case of a 31-year-old Indian man who presented with fevers, night sweats, weight loss, and epigastric pain. Abdominal magnetic resonance imaging (MRI) showed a pancreatic head mass. Biopsy of the mass was consistent with pancreatic tuberculosis...
August 2016: ACG Case Reports Journal
https://www.readbyqxmd.com/read/27790448/clinicopathological-characteristics-of-thymic-tuberculosis-a-rare-entity
#12
Keerthi Ramachandran Pillai, Meenu Prakash, Muktha Ramesh Pai
Tuberculosis is a severely debilitating disease and it rarely presents with involvement of the thymus. Only fifteen cases have been reported worldwide. We report a case of thymic tuberculosis in a 12-year-old female presenting with cervical lymphadenopathy. Computed tomographic imaging revealed a mediastinal mass which was then excised via thoracotomy. The gross appearance of the cut surface of both lobes was variegated with white, granular caseating material. Microscopy revealed multiple, caseating, epithelioid granulomas with dispersed Langhans giant cells surrounded by thymic parenchyma with Hassals corpuscles...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27790312/magnetic-resonance-imaging-and-genexpert-a-rapid-and-accurate-diagnostic-tool-for-the-management-of-tuberculosis-of-the-spine
#13
Ayush Sharma, Harvinder Singh Chhabra, Rajat Mahajan, Tarun Chabra, Sahil Batra
STUDY DESIGN: Retrospective study. PURPOSE: The aim of this study was to analyze various diagnostic tools, including GeneXpert, for the management of tuberculosis of the spine. OVERVIEW OF LITERATURE: Traditional diagnostic methods of microscopy, histology, and culture have low sensitivity and specificity for the management of tuberculosis of the spine. METHODS: Of the 262 treated cases of spinal tuberculosis, data on 1 year follow-up was available for 217 cases...
October 2016: Asian Spine Journal
https://www.readbyqxmd.com/read/27790302/urinary-mycobacterium-avium-presenting-as-sterile-pyuria
#14
Kai Yang, Mary Samplaski, Tony Mazzulli, Kirk Lo, Ethan Grober, Keith Allen Jarvi
A 65-year-old healthy woman presented with persistent, asymptomatic sterile pyuria detected by her family physician. While she did not have symptoms, the patient recounts that she has had cloudy urine for years. Cultures of the urine for bacteria showed no growth and no fungi were identified. First-morning urine samples were sent for both tuberculosis and nontuberculosis mycobacterium species testing. The culture grew genotypically identified Mycobaterium avium complex (MAC). Mantoux skin testing was positive...
May 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/27772758/role-of-18-f-fdg-pet-in-demonstrating-disease-burden-in-patients-with-tuberculous-meningitis
#15
Sanjay Gambhir, Mritunjai Kumar, Mudalsha Ravina, Sanjeev Kumar Bhoi, Jayantee Kalita, U K Misra
OBJECTIVE: To study the role of (18)fluoro-deoxy glucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) scan in documenting the disease burden in patients with tuberculous meningitis (TBM), and compare these findings with conventional imaging and magnetic resonance imaging (MRI). SUBJECTS AND METHODS: Ten patients with definite TBM were prospectively recruited. The severity of TBM was graded into stage I to III. The patients were subjected to whole body (18)F-FDG PET/CT imaging and MRI brain...
November 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27761291/langerhans-cell-histiocytosis-with-atypical-intervertebral-disc-and-sacroiliac-joint-involvement-mimicking-osteoarticular-tuberculosis-in-an-adult
#16
Zeynep Maraş Özdemir, Ayşegül Sağır Kahraman, Cemile Ayşe Görmeli, Reşit Sevimli, Nusret Akpolat
BACKGROUND: Langerhans cell histiocytosis (LCH), typically found in children, is a rare single or multisystem disorder with a wide range of clinical and radiological manifestations. Unusual presentations of LCH are occasionally encountered and it may be difficult to distinguish LCH from an infection or a benign or malignant tumor. RESULTS: A 35-year-old female presented with pain in her back and left buttock, malaise, and weight loss, with a duration of several months...
September 2016: Balkan Medical Journal
https://www.readbyqxmd.com/read/27758990/clinical-significance-of-the-galaxy-sign-in-patients-with-pulmonary-sarcoidosis-in-a-japanese-single-center-cohort
#17
Takashi Koide, Takeshi Saraya, Yayoi Tsukahara, Francesco Bonella, Eda Börner, Manabu Ishida, Yukari Ogawa, Ichiro Hirukawa, Miku Oda, Masafumi Shimoda, Kosuke Ohkuma, Masachika Fujiwara, Saori Takata, Takuma Yokoyama, Daisuke Kurai, Haruyuki Ishii, Hajime Goto, Hajime Takizawa
BACKGROUND: The galaxy sign is an irregularly marginated pulmonary nodule formed by a confluence of multiple small nodules, and it is a diagnostic radiological finding for pulmonary sarcoidosis. However, the clinical significance of the galaxy sign for sarcoidosis has been poorly investigated. OBJECTIVE: This study aimed to investigate the clinical significance and detailed radiological features of the galaxy sign in patients with pulmonary sarcoidosis. METHODS: We retrospectively reviewed 87 patients with biopsy-proven sarcoidosis and 108 patients with pulmonary tuberculosis...
October 7, 2016: Sarcoidosis, Vasculitis, and Diffuse Lung Diseases: Official Journal of WASOG
https://www.readbyqxmd.com/read/27753271/intravital-excitation-increases-detection-sensitivity-for-pulmonary-tuberculosis-by-whole-body-imaging-with-%C3%AE-lactamase-reporter-enzyme-fluorescence
#18
Fatemeh Nooshabadi, Hee-Jeong Yang, Yunfeng Cheng, Madeleine S Durkee, Hexin Xie, Jianghong Rao, Jeffrey D Cirillo, Kristen C Maitland
Tuberculosis is a pulmonary disease with an especially high mortality rate in immuno-compromised populations, specifically children and HIV positive individuals. The causative agent, Mycobacterium tuberculosis (Mtb), is a very slow growing and difficult organism to work with, making both diagnosis and development of effective treatments cumbersome. We utilize a fiber-optic fluorescence microendoscope integrated with a whole-body imaging system for in vivo Mtb detection. The system exploits an endogenous enzyme of Mtb (β-lactamase, or BlaC) using a BlaC-specific NIR fluorogenic substrate...
October 18, 2016: Journal of Biophotonics
https://www.readbyqxmd.com/read/27752009/prevalence-and-presentation-of-tuberculosis-among-hemodialysis-patients-in-khartoum-sudan
#19
Amin S I Banaga, Nihad K Siddiq, Randa T Alsayed, Rasha Babiker, Khalifa Elmusharaf
Tuberculosis (TB) is a major health problem in the developing countries. There are limited data about the prevalence of TB patients on maintenance hemodialysis (HD) in Sudan. The aim of this study is to identify the prevalence and presentation of TB among Sudanese maintenance HD patients. This is a hospital-based descriptive study. The participants of the study are all HD patients distributed in 13 HD centers in Khartoum and Khartoum North Provinces in Sudan. All patients attended the HD centers from November 1, 2014 to February 1, 2015, were interviewed by a questionnaire focused on personal and clinical data...
September 2016: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/27750273/a-case-report-of-severe-neuro-behcet-s-disease-treated-with-a-combination-of-immunosuppressives-and-a-tnf-inhibitor-a-difficult-therapeutic-choice
#20
Fatma Nur Korkmaz, Gulsen Ozen, Ali Uğur Ünal, Pınar Kahraman Koytak, Nese Tuncer, Haner Direskeneli
Abstract/ Resumo Behcet's disease (BD) is a multisystem inflammatory disorder characterized by recurrent oral and genital ulcers, skin lesions and uveitis. The nervous system involvement of BD, neuro-Behcet's disease (NBD), is one of the important causes of mortality of the disease. Herein, we present a 29-year-old male with parenchymal NBD who has progressed rapidly and was managed with an uncommon aggressive immunosuppresive combination therapy. The patient first presented six years ago with vertigo and difficulty in talking and walking...
September 28, 2016: Acta Reumatológica Portuguesa
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