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autologous fat transfer

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https://www.readbyqxmd.com/read/29175445/adipocyte-biology-in-breast-cancer-from-silent-bystander-to-active-facilitator
#1
REVIEW
Junjeong Choi, Yoon Jin Cha, Ja Seung Koo
Adipocytes account for the largest proportion among the cells that comprise breast tissue; therefore, they are considered to be a critical cell type in the tumor microenvironment of breast cancer. In breast cancer, adipocytes are not only found adjacent to cancer cells, but they also play an active role in the entire process of cancer development, progression, metastasis, and treatment response. Factors including the secretion of adipokines such as leptin and adiponectin, as well as autotaxin, interleukin 6, tumor necrosis factor alpha, and hepatic growth factor, metabolic remodeling that supports the growth of breast cancer by transfer of fatty acids to increase mitochondrial β-oxidation, extracellular matrix remodeling and endotrophin production from type IV collagen, and cancer-associated fibroblast phenotype changes have all been implicated in this comprehensive process...
November 21, 2017: Progress in Lipid Research
https://www.readbyqxmd.com/read/29114637/percutaneous-fat-transfer-to-treat-knee-osteoarthritis-symptoms-preliminary-results
#2
Ezio Adriani, Mariagrazia Moio, Berardino Di Paola, Walter Salustri, Andrea Alfieri, Paola Parisi, Marco Ruggiero, Zack Borab, Bruno Carlesimo
Purpose  This study aims to evaluate the safety and efficacy of autologous aspirated and purified fat tissue injected percutaneously into the knee joint for the treatment of symptomatic osteoarthritis (OA). Methods  We reviewed 30 patients, who received an autologous percutaneous fat injection for the treatment of knee OA, from January 2012 to March 2015. Mean patients' age was 63.3 ± 5.3 years (range, 50-80 years). Body mass index was 25.1 ± 1.7. Clinical evaluation was based on pain visual analog scale (VAS) and WOMAC score for functional and subjective assessment...
June 2017: Joints
https://www.readbyqxmd.com/read/29076327/autogenous-fat-grafting-for-mild-to-moderate-postoperative-temporal-hollowing-after-decompressive-craniectomy-1-year-follow-up
#3
Jaemin Choi, Hyungon Choi, Donghyeok Shin, Jeenam Kim, Myungchul Lee, Soonheum Kim, Dongin Jo, Cheolkeun Kim
>Background: Temporal hollowing is inevitable after decompressive craniectomy. This complication affects self- perception and quality of life, and various techniques and materials have therefore been used to restore patients' confidence. Autologous fat grafting in postoperative scar tissue has been considered challenging because of the hostile tissue environment. However, in this study, we demonstrate that autologous fat grafting can be a simple and safe treatment of choice, even for postoperative depressed temporal scar tissue...
October 27, 2017: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/29044361/percutaneous-myotomy-with-a-small-needle-knife-and-lipoinjection-for-treatment-of-glabellar-frown-lines
#4
Xiaogen Hu, Zhiqiang Xue, Huijie Qi, Bo Chen
Background: Glabellar frown lines are a common aesthetic concern, and minimally invasive techniques to treat frown lines have become popular. Objectives: The authors developed a technique to minimize frown lines by means of percutaneous myotomy with a small needle-knife and lipoinjection. Methods: Sixty-nine patients underwent treatment of the glabellar frown lines in a prospective study. Percutaneous myotomy of the corrugator supercilii and procerus was conducted with a small needle-knife, and autologous fat was transferred to the glabellar region...
October 16, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29040029/autologous-fat-transfer-with-seffi-superficial-enhanced-fluid-fat-injection-technique-in-periocular-reconstruction
#5
Benjamin Riesco, Cristina Abascal, Ana Duarte, Rocio Mariel Flores, Guillermina Rouaux, Raul Sampayo, Francesco Bernardini, Martin Devoto
PURPOSE: To evaluate the aesthetic and functional outcomes of autologous fat transfer using the SEFFI (superficial enhanced fluid fat injection) technique for reconstruction of the periocular area. METHODS: Autologous fat injections prepared with the 0.5 mL and 0.8 mL SEFFI technique were used in four patients for periocular rehabilitation. RESULTS: Case 1 (C1): A patient with left-sided progressive facial hemiatrophy underwent ipsilateral volumizing with 0...
October 17, 2017: Orbit
https://www.readbyqxmd.com/read/29036027/early-macrophage-infiltration-improves-the-fat-graft-survival-by-inducing-angiogenesis-and-hematopoietic-stem-cell-recruitment
#6
Junrong Cai, Jingwei Feng, Kaiyang Liu, Shaolong Zhou, Feng Lu
BACKGROUND: Fat grafting is a popular soft tissue filler method; however, its results are variable and technique-dependent. Macrophages are present in fat grafts and closely associated with tissue regeneration. We hypothesized that activation/depletion of early macrophages in transferred fat improves/impairs fat graft survival. METHODS: Mouse inguinal fat (~150 mg) was transferred autologously. Fat grafting was first performed without other manipulations to obtain baseline information...
October 12, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29025229/mechanical-supplementation-with-the-stromal-vascular-fraction-yields-improved-volume-retention-in-facial-lipotransfer-a-1-year-comparative-study
#7
Natale Ferreira Gontijo-de-Amorim, Luiz Charles-de-Sá, Gino Rigotti
Background: Unpredictable volume maintenance in the long term is a major limitation of autologous fat grafting. Objectives: The authors compared results of autologous lipotransfer to the face with or without enrichment of fat with the stromal vascular fraction (SVF). Methods: Thirty patients with asymmetric depletion of facial volume were included in a prospective study. Patients were randomly assigned to undergo a single session of autologous fat transfer with washed adipose tissue (control group) or with washed adipose tissue combined with the pellet of centrifuged lipoaspirate, which contained the SVF (enriched group)...
October 1, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/28989237/lipofilling-effects-after-breast-cancer-surgery-in-post-radiation-patients-an-analysis-of-results-and-algorithm-proposal
#8
Manuel Debald, Thomas Pech, Christina Kaiser, Mignon-Denise Keyver-Paik, Gisela Walgenbach-Bruenagel, Joerg C Kalff, Walther Kuhn, Klaus J Walgenbach
BACKGROUND: Lipofilling or autologous fat transfer is an established technique in plastic surgery. Herein, we describe the lipofilling effects after implant-based breast reconstruction in post-radiation patients and propose an algorithm for indication of lipofilling. METHODS: Forty patients with a history of breast cancer were included in this retrospective analysis. Patients had undergone either breast conserving therapy or mastectomy. Twenty-six patients underwent additional radiation therapy...
2017: European Journal of Plastic Surgery
https://www.readbyqxmd.com/read/28969194/evaluation-of-use-of-adipose-cells-in-various-procedures-of-plastic-surgery-and-its-volumetric-quantification-using-high-resolution-ultrasound
#9
Somashekar Gejje, Arun K Singh, P K Srivastava, Madhumati Goel, Vijay Kumar, Amrita Hongal
INTRODUCTION: Autologous fat transfer is based on one of the principles of plastic surgery, replace like with like. It is used in wide variety of aesthetic procedures such as lip, facial augmentation and reconstructive procedures such as involutional disorders, post traumatic defects etc. AIM: This prospective study was on the use of adipose cells in various procedures of plastic surgery, the role of high resolution ultrasound in estimating the volume of the grafted fat, comparison of the results based on the different donor sites of the harvested fat and comparison of the effectiveness of grafted fat in extremities and craniofacial region...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28949034/comparing-the-thoracodorsal-and-internal-mammary-vessels-as-recipients-for-microsurgical-autologous-breast-reconstruction-a-systematic-review-and-meta-analysis
#10
REVIEW
Osama A Samargandi, Jessica Winter, Joseph P Corkum, Sarah Al Youha, Simon Frank, Jason Williams
BACKGROUND: Our aim was to determine whether the thoracodorsal (Td) vessels have comparable clinical outcomes to the internal mammary (IM) vessels as recipients for autologous free tissue transfer for breast reconstruction. METHODS: Systematic searches of MEDLINE, EMBASE, CENTRAL, and World of Science from inception to June 2016 were performed by two independent reviewers. Studies that included adult females undergoing autologous free tissue transfer for breast reconstruction were selected...
September 26, 2017: Microsurgery
https://www.readbyqxmd.com/read/28841614/autologous-fat-grafting-as-a-novel-antiestrogen-vehicle-for-the-treatment-of-breast-cancer
#11
Scott Thomas, Stephanie Chen, Hani Sbitany, Edwin Kwon, Merisa Piper, Jeenah Park, Manuela Terranova Barberio, Nela Pawlowska, Pamela N Munster
BACKGROUND: Adipose fat transfer is increasingly used for contour corrections of the tumor bed after lumpectomy and breast reconstructions after mastectomy. The lipophilic nature of the fat tissue may render adipocytes an ideal vehicle with which to deliver a high boost of an antiestrogen to the tumor bed to serve as an adjunct systemic hormonal therapy. The authors therefore tested whether adipocytes could safely be loaded with an antiestrogen and allow for release at therapeutic concentrations to treat breast cancer...
September 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28791455/fat-injection-a-systematic-review-of-injection-volumes-by-facial-subunit
#12
REVIEW
Shirley Shue, David E Kurlander, Bahman Guyuron
BACKGROUND: Fat grafting to the aging face has become an integral component of esthetic surgery. However, the amount of fat to inject to each area of the face is not standardized and has been based mainly on the surgeon's experience. The purpose of this study was to perform a systematic review of injected fat volume to different facial zones. METHODS: A systematic review of the literature was performed through a MEDLINE search using keywords "facial," "fat grafting," "lipofilling," "Coleman technique," "autologous fat transfer," and "structural fat grafting...
August 8, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28783406/autologous-fat-transfer-for-breast-surgery
#13
Ketan Agarwal, Meera Mistry
Cosmetic and reconstructive surgeries always have a primary aim of the best outcome for the patient, with a big emphasis on the aesthetics. Lipomodelling is one such technique, originally described over a century ago but still used to this day, to provide a patient with the highest quality results. This is particularly true for lipomodelling of the breast, whether it be purely cosmetic, or for a post-mastectomy reconstruction for a breast cancer patient. Lipomodelling provides an effective way of restoring and even improving the look and aesthetics of the breast and of helping achieve the patient's expectations...
August 2, 2017: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/28749069/fatal-fat-embolism-after-penis-enlargement-by-autologous-fat-transfer-a-case-report-and-review-of-the-literature
#14
Brita Zilg, Petra Råsten-Almqvist
Fat embolism is an incidental finding in cases of long bone fractures or other trauma, but it is also associated with liposuction and autologous fat transfer, a procedure where fat from liposuction is injected back into the same patient's face, breast, buttocks or penis. We here present a case of sudden death by fat embolism in a healthy young male, caused by a simple penis enlargement procedure, in which fat was injected into the penis shaft. We suggest that the risk of fat embolization might be higher when pretraumatized tissue is subjected to fat injection, like in this case, where a penis elongation was performed before the fat injection...
September 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28746280/discussion-autologous-fat-transfer-for-thumb-carpometacarpal-joint-osteoarthritis-a-prospective-study
#15
COMMENT
Roger K Khouri, Roger K Khouri
No abstract text is available yet for this article.
August 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28691024/self-assembling-rada16-i-peptide-hydrogel-scaffold-loaded-with-tamoxifen-for-breast-reconstruction
#16
Huimin Wu, Ting Zhou, Lin Tian, Zhengchao Xia, Feng Xu
More and more breast cancer patients prefer autologous fat tissue transfer following lumpectomy to maintain perfect female characteristics. However, the outcome was not satisfactory due to the transplanted fat absorption. In this study, we prepared two RADA16-I peptide scaffolds with and without tamoxifen. Both scaffolds were transparent, porous, and hemisphere-shaped. The hADSCs isolated from liposuction were attached to the scaffold. The growth inhibition of the hADSCs induced by TAM in 2-demensional (2D) culture was higher than that in TAM-loaded hydrogel scaffold 3D culture (P < 0...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28684338/midface-rejuvenation-surgery-combining-preperiosteal-midcheek-lift-lower-blepharoplasty-with-orbital-fat-preservation-and-autologous-fat-grafting
#17
H Chatel, B Hersant, R Bosc, S La Padula, J P Meningaud
OBJECTIVE: The aim of this study was to describe a technique for midface rejuvenation combining lower blepharoplasty, midcheek lift and autologous fat transfer. METHODS: All patients who underwent a midface rejuvenation procedure performed by the same surgeon and using a classic subciliary blepharoplasty surgical approach were identified. The technique combined three distinct procedures: lower blepharoplasty with use of a transposition flap of orbital adipose tissue in the medial and central compartment to reduce the subpalpebral bags and attenuate the palpebrojugual sulcus; midcheek lift in the preperiosteal plane with trans-osseous fixation exerting traction on the soft tissues of the cheek along several vectors; autologous fat transfer to offset the loss of volume in the target area...
July 3, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28643006/complications-of-fat-transfer-for-breast-augmentation
#18
Paraskevas Kontoes, George Gounnaris
Autologous fat grafting is quite common for breast augmentations as well as for reconstructive breast surgery. Coleman has described the surgical technique of fat grafting. Fat is harvested, and after centrifugation and refinement, blunt infiltration cannulas are used to place the fat through small incisions. The grafted tissue is placed in small aliquots with each withdrawal of the cannula. In order to achieve an aesthetically pleasing contour of the breast, the fat should be layered into different levels from the chest wall to the skin...
October 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28624714/patient-reported-outcomes-of-autologous-fat-grafting-after-breast-cancer-surgery
#19
A W W Brown, M Kabir, K A Sherman, F Meybodi, J R French, E B Elder
INTRODUCTION: Autologous fat grafting (AFG) can be used as an adjunct in breast cancer surgery to improve contour defects. Few previous studies have assessed patient reported outcomes (PROs) for AFG. This study analysed AFG use and assessed PROs in terms of physical and psychosocial well-being. MATERIALS AND METHODS: All patients undergoing AFG were identified from a prospective database and asked to complete the validated BREAST-Q questionnaire and a tool to assess patient-perceived change after AFG (5-point Likert-type scale)...
June 15, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28599842/composite-breast-reconstruction-implant-based-breast-reconstruction-with%C3%A2-adjunctive-lipofilling
#20
C E Sommeling, K Van Landuyt, H Depypere, R Van den Broecke, S Monstrey, P N Blondeel, W A Morrison, F B Stillaert
INTRODUCTION: Options for breast reconstructions enclose autologous tissue transfers or implants. Fat grafting is gaining more interest in this specific field of breast surgery. This study concentrates on the technique and aesthetic results of breast reconstruction with fat grafts combined with implants, in women who have undergone total mastectomy. METHODS: Breast reconstructions (n = 23) was performed using a protocol of intratissular expansion with serial deflation-lipofilling...
August 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
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