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autologous fat transfer

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https://www.readbyqxmd.com/read/28390738/immediate-lipofilling-in-breast-conserving-surgery
#1
L R Khan, C R Raine, J M Dixon
BACKGROUND: The aim of breast conserving surgery (BCS) is to excise the cancer with clear margins whilst at the same time leaving a good or excellent cosmetic result. A significant percentage of women, who have large cancers or have limited breast volumes, achieve poor cosmetic outcomes. BCS with immediate volume replacement using lipofilling or autologous fat transfer is a new technique. The aim of this study was to evaluate the cosmetic outcomes of a pilot study of patients having BCS and immediate lipofilling performed in The Edinburgh Breast Unit...
March 27, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28372485/a-review-of-cell-based-strategies-for-soft-tissue-reconstruction
#2
Elizabeth A Brett, Natalie Chung, Tripp Leavitt, Arash Momeni, Michael T Longaker, Derrick C Wan
Soft tissue reconstruction to restore volume to damaged or deficient tissue beneath the skin remains a challenging endeavor. Current techniques are centered around autologous fat transfer, or the use of synthetic substitutes, however a great deal of scientific inquiry has been made into both the molecular mechanisms involved in, as well as limitations of, de novo adipogenesis, i.e. the formation of new adipose tissue from precursor cells. To best comprehend these mechanisms, an understanding of defined markers for adipogenic differentiation, as well as knowledge of both commercially available and primary cell lines that enable in vitro and in vivo studies is necessary...
April 3, 2017: Tissue Engineering. Part B, Reviews
https://www.readbyqxmd.com/read/28369017/autologous-fat-transfer-for-thumb-carpometacarpal-joint-osteoarthritis-a-prospective-study
#3
Christian Herold, Hans-Oliver Rennekampff, Robert Groddeck, Sixtus Allert
BACKGROUND: Most surgeries for CMC joint osteoarthritis of the thumb irreversibly alter or destroy the anatomy. There is a high demand for minimal invasive alternatives. We report the results of autologous fat transfer for treatment of thumb CMC joint osteoarthritis. METHODS: In a prospective study 50 patients with thumb CMC joint osteoarthrits were observed for one year after autologous fat transfer. Manual liposuction and centrifugation was performed. Pain rating as per visual analog pain scale (VAS), objective force of pinch grip and fist closure and DASH scores before and after the treatment were analysed...
March 31, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28254844/vegf-a-expressing-adipose-tissue-shows-rapid-beiging-enhanced-survival-after-transplantation-and-confers-il4-independent-metabolic-improvements
#4
Jiyoung Park, Min Kim, Kai Sun, Yu Aaron An, Xue Gu, Philipp E Scherer
Adipocyte-derived VEGF-A plays a crucial role in angiogenesis and contributes to adipocyte function and systemic metabolism, such as insulin resistance, chronic inflammation and beigeing of subcutaneous adipose tissue. Utilizing a doxycycline (Dox)-inducible adipocyte-specific VEGF-A overexpressing mouse model, we investigated the dynamics of local VEGF-A effects on tissue beiging of adipose tissue transplants. VEGF-A overexpression in adipocytes triggers angiogenesis. We also observe a rapid appearance of beige fat cells in subcutaneous white adipose tissue (sWATs) within as early as 2 days post induction of VEGF-A...
March 2, 2017: Diabetes
https://www.readbyqxmd.com/read/28215817/free-dermal-fat-graft-reconstruction-of-the-head-and-neck-an-alternate-reconstructive-option
#5
Adam Honeybrook, Sanjay M Athavale, Sanjeet V Rangarajan, Sarah L Rohde, James L Netterville
OBJECTIVES: Ablative procedures of the head and neck often result in significant facial and cervical irregularities and cosmetic asymmetry. The deformity resulting from ablative procedures of the head and neck is a significant source of cosmetic morbidity and postoperative dissatisfaction. Reconstruction of post-ablative defects in the head and neck can employ a broad range of techniques, ranging from primary closure to free tissue transfer. The free dermal fat graft (FDFG) is one such option and has been used to repair volume defects of varying sizes after common head and neck procedures such as parotidectomy...
January 27, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28177972/sustained-overcorrection-after-autologous-facial-fat-grafting-in-the-pediatric-population-a-case-series
#6
Kathryn Ries Tringale, Samuel Lance, Anna Schoenbrunner, Amanda A Gosman
INTRODUCTION: Autologous fat grafting is a valuable tool in the correction of facial soft tissue asymmetry and volume deficits. Pubertal growth and fluctuations in body mass present unique challenges to achieving satisfactory results after autologous fat transfer in the pediatric population. Few studies exist describing the outcomes and complications of pediatric facial fat grafting. The objective of this study is to identify the complication profile and outcomes after autologous fat grafting for the correction of facial asymmetry and volume deficits in the pediatric population...
May 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28008461/lower-leg-augmentation-with-fat-grafting-mri-and-histological-examination
#7
Violeta Skorobac Asanin, Jelena Sopta
INTRODUCTION: Nowadays, there is an increasing demand for contouring of the entire lower leg, in addition to corrections at the level of the muscle only. Accordingly, it becomes advantageous to use fat tissue for this purpose, for its availability in high quantities, potential for its easy implantation in all leg parts, biological compatibility, low antigen potential, and minimal donor morbidity. METHODS: Forty-eight female patients, aged 20-54 (47.1 % younger than 35 and 52...
December 23, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/27958596/lipofilling-as-refinement-procedure-in-maxillo-mandibular-malformations
#8
D Cervelli, G Gasparini, A Moro, S Pelo, E Foresta, F Grussu, G D'Amato, P De Angelis, G Saponaro
Maxillo-mandibular asymmetry has numerous aetiologies: congenital, traumatic, iatrogenic and post-oncologic. Patients with congenital dentofacial malformations are generally submitted to orthognathic surgery and/or additional procedures (genioplasty, alloplastic implants) with satisfactory results. However, despite achieving skeletal symmetry, noticeable facial asymmetry may persist.This study was performed in 45 patients (29 women and 16 men) operated between December 2012 and June 2014. All patients were affected by maxilla-mandibular asymmetry and underwent orthognatic surgery for hard tissue correction of the deformity...
October 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/27893635/orthognathic-surgery-with-simultaneous-autologous-fat-transfer-for-correction-of-facial-asymmetry
#9
Yu-Ching Wang, Christopher Glenn Wallace, Betty Chien-Jung Pai, Hui-Ling Chen, Yueh-Tse Lee, Yen-Chang Hsiao, Chun-Shin Chang, Yu-Fang Liao, Philip Kuo-Ting Chen, Yu-Ray Chen
BACKGROUND: Most patients treated with orthognathic surgery for facial asymmetry would value improvement in residual soft tissue asymmetry. Autologous fat transfer is widely used to augment facial soft tissue. We assessed the effect of combining orthognathic surgery with autologous fat transfer for treating patients with facial asymmetry. METHODS: In this retrospective study, 15 consecutive adults underwent combined orthognathic surgery and autologous fat transfer between January 2013 and December 2015...
November 21, 2016: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27881936/autologous-fat-transfer-to-the-subcutaneous-tissue-in-the-context-of-breast-reconstructive-procedures
#10
REVIEW
Pawel Szychta, Marek Zadrozny, Jan Rykala, Lukasz Banasiak, Henryk Witmanowski
Autologous fat transfer (AFT) is an appropriate technique for aesthetic rejuvenation of the face, aesthetic enhancement of hands, correction of the facial appearance in various disorders and constitutes a surgical alternative of treatment of numerous breast deformities ranging from distorting posttraumatic scars, post-eczema lesions, post-burn deformities to partial or total breast reconstruction. Our work is aimed to familiarize dermatologists with the technique of harvesting and implanting the aspirate of adipose cells in patients consulted for deformities of the breast...
October 2016: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/27832668/-current-perceptions-of-lipofilling-on-the-basis-of-the-new-guideline-on-autologous-fat-grafting
#11
L Prantl, H O Rennekampff, R E Giunta, Y Harder, D von Heimburg, N Heine, C Herold, U Kneser, F Lampert, H G Machens, U Mirastschijski, D Müller, N Pallua, T Schantz, A Schönborn, K Ueberreiter, C H Witzel, G Bull, D Rezek, G Sattler, P M Vogt, R E Horch
Introduction: Autologous fat transfer has recently become an increasingly popular surgical procedure and comprises harvesting, processing and transplantation of adipose tissue, as well as professional follow-up care. This method, as a surgical procedure, can be utilised for trauma-, disease- or age-related soft tissue volume deficits and soft tissue augmentation. As usage is increasing, but the variables of fat harvest, specific indications and fashion of fat transfer are poorly defined, there is a great demand for development of a guideline in the field of reconstructive and aesthetic surgery...
December 2016: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/27770576/improved-pocket-control-in-immediate-microsurgical-breast-reconstruction-with-simultaneous-implant-placement-through-the-use-of-mesh
#12
Arash Momeni, Suhail K Kanchwala
BACKGROUND: Autologous breast reconstruction is associated with long-term patient satisfaction that is superior to implant-based approaches. Occasionally, however, patients who desire autologous reconstruction present with inadequate donor-site volume. A hybrid approach, combining free flap reconstruction with simultaneous implant placement, is a solution. We present our experience with the use of mesh for improved pocket control using this reconstructive modality. METHODS: A retrospective analysis of a prospectively maintained database of patients undergoing autologous breast reconstruction was performed...
October 22, 2016: Microsurgery
https://www.readbyqxmd.com/read/27673540/a-retrospective-analysis-of-secondary-revisions-after-face-transplantation-assessment-of-outcomes-safety-and-feasibility
#13
Mario A Aycart, Muayyad Alhefzi, Maximilian Kueckelhaus, Nicco Krezdorn, Ericka M Bueno, Edward J Caterson, Julian J Pribaz, Bohdan Pomahac
BACKGROUND: Face transplantation has emerged as a viable option for certain patients in the treatment of devastating facial injuries. However, as with autologous free tissue transfer, the need for secondary revisions in face transplantation also exists. The authors' group has quantified the number of revision operations in their cohort and has assessed the rationale, safety, and outcomes of posttransplantation revisions. METHODS: A retrospective analysis of prospectively collected data of the authors' seven face transplants was performed from April of 2009 to July of 2015...
October 2016: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27618391/autologous-fat-transfer-for-breast-augmentation-a-review
#14
REVIEW
Mohammed A Al Sufyani, Abdullah H Al Hargan, Nayf A Al Shammari, Mohannad A Al Sufyani
BACKGROUND: The use of autologous fat transfer for breast augmentation is still controversial due to ongoing concerns regarding its efficacy and safety, most notably, concerns about breast cancer risk and detection. OBJECTIVE: To summarize the current knowledge on the safety and efficacy of autologous fat transfer for breast augmentation with focus on clinical techniques, outcome, and complications. METHODS: A thorough search of the literature was conducted using the terms autologous fat transfer, autologous fat grafting, and breast augmentation in the Medline and Embase databases, and relevant English and German language articles were included...
November 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27562834/fat-grafting-with-tissue-liquefaction-technology-as-an-adjunct-to-breast-reconstruction
#15
Utku Dolen, Justin B Cohen, Bo Overschmidt, Marissa M Tenenbaum, Terence M Myckatyn
BACKGROUND: Tissue liquefaction technology (TLT) delivers warmed saline from the liposuction cannula tip at low pressure pulses to disaggregate adipocytes. This technology differs significantly from that used in other liposuction devices including water jet-assisted liposuction. Here we introduce our early experience with this technology in the setting of fat transfer for revision breast reconstruction. METHODS: A retrospective chart review of 136 consecutive patients who underwent fat harvest with TLT and subsequent transfer into 237 breast reconstructions was conducted at a single institution...
December 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/27562152/-surgical-strategy-for-postburn-facial-scar-contracture
#16
H Jiang, A T Liu
Postburn facial scar contracture, which can cause disfigurement and functional impairment, is a major therapeutic challenge. Except for some scars with severe functional impairments such as ectropion of lid, obstruction of nostril, microstomia, and so on, other kinds of facial scars are recommended to be reconstructed after they become sufficiently softened. The selection of specific methods depends on the characteristics of the facial scar. The methods includ direct closure after resection, full or split-thickness skin transplantation, pedicled flap, distant flap, and free flap transfer, and tissue expansion...
August 20, 2016: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/27536489/plantar-fat-grafting-and-tendon-balancing-for-the-diabetic-foot-ulcer-in-remission
#17
Cynthia A Luu, Ethan Larson, Timothy M Rankin, Jennifer L Pappalardo, Marvin J Slepian, David G Armstrong
We report on the use of free fat grafting as a means of redistributing normal and shear stress after healing of plantar diabetic foot wounds. Although fat augmentation (lipofilling) has been described previously as an approach to supplement defects and prevent atrophy, including use as an adjunct to wound healing and to mitigate pain in the foot, we are unaware of any reports in the medical literature that have described its use in the high-risk diabetic foot in remission. An active 37-year-old man with type 2 diabetes and neuropathy presented with gangrene of his fifth ray, which was amputated...
July 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/27513428/the-effect-of-low-dose-methotrexate-on-autologous-fat-graft-survival
#18
Elif Sari, Bülent Bakar, Bahram Sarkarati, Önder Bozdoğan, Tarık Çavuşoğlu
BACKGROUND/AIM: The survival of autologous fat graft tissue is dependent on various factors such as vascularization and inflammation. The aim of the present study was to evaluate the possible beneficial effects of low-dose methotrexate (LD-MTX) on fat graft volume and survival. MATERIALS AND METHODS: A total of 13 male Wistar albino rats were divided into two groups, a control group and an LD-MTX group. An autologous fat graft obtained from the inguinal region of each rat was transferred to its back...
2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/27496689/quality-of-life-outcomes-associated-with-treatment-of-human-immunodeficiency-virus-hiv-facial-lipoatrophy
#19
REVIEW
Christina N Kraus, Lance W Chapman, Dorota Z Korta, Christopher B Zachary
Facial lipoatrophy (FLA), characterized by a decrease in facial volume, has a high prevalence in patients with human immunodeficiency virus (HIV) infection treated with long-term highly active antiretroviral therapy (HAART). The social stigmatization that results from such changes in facial appearance has led some HIV patients to discontinue HAART. The use of fillers is one method of restoring facial volume. A critical outcome of treatment concerns the patient's quality of life (QoL). Although many studies have assessed patient satisfaction, as well as the social and psychological outcomes associated with the correction of HIV FLA, fewer studies have assessed QoL...
December 2016: International Journal of Dermatology
https://www.readbyqxmd.com/read/27439536/massive-cerebral-infarction-following-facial-fat-injection
#20
Xiao Shen, Qi Li, Hengshu Zhang
BACKGROUND: Autologous facial fat injection is becoming popular around the world. Semiliquid fat grafts are used for correction of deformities or aesthetic purposes. Fat transfer is a mini-invasive surgical procedure, but causes severe complications occasionally. METHODS: A 30-year-old female patient presented to our hospital with sudden unconsciousness and left limb weakness 8 h after facial fat injection. Brain arteriography (CTA) and venography were performed immediately after her admission...
October 2016: Aesthetic Plastic Surgery
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