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"Agent-based modeling"

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https://www.readbyqxmd.com/read/28094523/combining-agent-based-modeling-and-life-cycle-assessment-for-the-evaluation-of-mobility-policies
#1
Florent Querini, Enrico Benetto
No abstract text is available yet for this article.
January 17, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28086846/stochastic-agent-based-modeling-of-tuberculosis-in-canadian-indigenous-communities
#2
Ashleigh R Tuite, Victor Gallant, Elaine Randell, Annie-Claude Bourgeois, Amy L Greer
BACKGROUND: In Canada, active tuberculosis (TB) disease rates remain disproportionately higher among the Indigenous population, especially among the Inuit in the north. We used mathematical modeling to evaluate how interventions might enhance existing TB control efforts in a region of Nunavut. METHODS: We developed a stochastic, agent-based model of TB transmission that captured the unique household and community structure. Evaluated interventions included: (i) rapid treatment of active cases; (ii) rapid contact tracing; (iii) expanded screening programs for latent TB infection (LTBI); and (iv) reduced household density...
January 13, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28076659/an-empirical-agent-based-model-to-simulate-the-adoption-of-water-reuse-using-the-social-amplification-of-risk-framework
#3
Venu Kandiah, Andrew R Binder, Emily Z Berglund
Water reuse can serve as a sustainable alternative water source for urban areas. However, the successful implementation of large-scale water reuse projects depends on community acceptance. Because of the negative perceptions that are traditionally associated with reclaimed water, water reuse is often not considered in the development of urban water management plans. This study develops a simulation model for understanding community opinion dynamics surrounding the issue of water reuse, and how individual perceptions evolve within that context, which can help in the planning and decision-making process...
January 11, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/28060865/agent-based-modeling-of-mitochondria-links-sub-cellular-dynamics-to-cellular-homeostasis-and-heterogeneity
#4
Giovanni Dalmasso, Paula Andrea Marin Zapata, Nathan Ryan Brady, Anne Hamacher-Brady
Mitochondria are semi-autonomous organelles that supply energy for cellular biochemistry through oxidative phosphorylation. Within a cell, hundreds of mobile mitochondria undergo fusion and fission events to form a dynamic network. These morphological and mobility dynamics are essential for maintaining mitochondrial functional homeostasis, and alterations both impact and reflect cellular stress states. Mitochondrial homeostasis is further dependent on production (biogenesis) and the removal of damaged mitochondria by selective autophagy (mitophagy)...
2017: PloS One
https://www.readbyqxmd.com/read/28053880/adapting-axelrod-s-cultural-dissemination-model-for-simulating-peer-effects
#5
Christian Hofer, Gernot Lechner, Thomas Brudermann, Manfred Füllsack
We present a generic method for considering incomplete but gradually expandable sociological data in agent-based modeling based on the classic model of cultural dissemination by Axelrod. Our method extension was inspired by research on the diffusion of citizen photovoltaic initiatives, i.e. by initiatives in which citizens collectively invest in photovoltaic plants and share the profits. Owing to the absence of empirical interaction parameters, the Axelrod model was used as basis for considering peer effects with contrived interaction data that can be updated from empirical surveys later on...
2017: MethodsX
https://www.readbyqxmd.com/read/28048970/partner-selection-and-emergence-of-the-merit-based-equity-norm
#6
Hirofumi Takesue
The merit-based equity norm is a widely observed principle of fairness in resource distribution, in which the resources acquired by each individual are expected to be proportional to the contribution. Despite the empirical significance of this principle, theoretical progress in evolutionary explanations of the fairness norm has been limited to an egalitarian norm. In this study, we examined the effect of partner selection on the evolution of the merit-based equity norm in a simple bargaining game. Our agent-based model demonstrates that the merit-based equity norm emerges when the agent can choose to continue the current partnership based on the bargaining result, whereas the egalitarian norm arises in a random matching situation...
December 31, 2016: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/28045533/computational-model-of-secondary-palate-fusion-and-disruption
#7
M Shane Hutson, Maxwell C K Leung, Nancy Baker, Richard M Spencer, Thomas B Knudsen
Morphogenetic events are driven by cell-generated physical forces and complex cellular dynamics. To improve our capacity to predict developmental effects from chemical-induced cellular alterations, we built a multi-cellular agent-based model in CompuCell3D that recapitulates the cellular networks and collective cell behavior underlying growth and fusion of the mammalian secondary palate. The model incorporated multiple signaling pathways (TGFβ, BMP, FGF, EGF, SHH) in a biological framework to recapitulate morphogenetic events from palatal outgrowth through midline fusion...
January 3, 2017: Chemical Research in Toxicology
https://www.readbyqxmd.com/read/28032590/predicting-the-impact-of-combined-therapies-on-myeloma-cell-growth-using-a-hybrid-multi-scale-agent-based-model
#8
Zhiwei Ji, Jing Su, Dan Wu, Huiming Peng, Weiling Zhao, Brian Nlong Zhao, Xiaobo Zhou
Multiple myeloma is a malignant still incurable plasma cell disorder. This is due to refractory disease relapse, immune impairment, and development of multi-drug resistance. The growth of malignant plasma cells is dependent on the bone marrow (BM) microenvironment and evasion of the host's anti-tumor immune response. Hence, we hypothesized that targeting tumor-stromal cell interaction and endogenous immune system in BM will potentially improve the response of multiple myeloma (MM). Therefore, we proposed a computational simulation of the myeloma development in the complicated microenvironment which includes immune cell components and bone marrow stromal cells and predicted the effects of combined treatment with multi-drugs on myeloma cell growth...
December 9, 2016: Oncotarget
https://www.readbyqxmd.com/read/28031023/can-longitudinal-generalized-estimating-equation-models-distinguish-network-influence-and-homophily-an-agent-based-modeling-approach-to-measurement-characteristics
#9
Kori Sauser Zachrison, Theodore J Iwashyna, Achamyeleh Gebremariam, Meghan Hutchins, Joyce M Lee
BACKGROUND: Connected individuals (or nodes) in a network are more likely to be similar than two randomly selected nodes due to homophily and/or network influence. Distinguishing between these two influences is an important goal in network analysis, and generalized estimating equation (GEE) analyses of longitudinal dyadic network data are an attractive approach. It is not known to what extent such regressions can accurately extract underlying data generating processes. Therefore our primary objective is to determine to what extent, and under what conditions, does the GEE-approach recreate the actual dynamics in an agent-based model...
December 28, 2016: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28028479/impacts-of-land-use-management-on-ecosystem-services-and-biodiversity-an-agent-based-modelling-approach
#10
Thomas J Habib, Scott Heckbert, Jeffrey J Wilson, Andrew J K Vandenbroeck, Jerome Cranston, Daniel R Farr
The science of ecosystem service (ES) mapping has become increasingly sophisticated over the past 20 years, and examples of successfully integrating ES into management decisions at national and sub-national scales have begun to emerge. However, increasing model sophistication and accuracy-and therefore complexity-may trade-off with ease of use and applicability to real-world decision-making contexts, so it is vital to incorporate the lessons learned from implementation efforts into new model development. Using successful implementation efforts for guidance, we developed an integrated ES modelling system to quantify several ecosystem services: forest timber production and carbon storage, water purification, pollination, and biodiversity...
2016: PeerJ
https://www.readbyqxmd.com/read/28027323/a-multi-host-agent-based-model-for-a-zoonotic-vector-borne-disease-a-case-study-on-trypanosomiasis-in-eastern-province-zambia
#11
Simon Alderton, Ewan T Macleod, Neil E Anderson, Kathrin Schaten, Joanna Kuleszo, Martin Simuunza, Susan C Welburn, Peter M Atkinson
BACKGROUND: This paper presents a new agent-based model (ABM) for investigating T. b. rhodesiense human African trypanosomiasis (rHAT) disease dynamics, produced to aid a greater understanding of disease transmission, and essential for development of appropriate mitigation strategies. METHODS: The ABM was developed to model rHAT incidence at a fine spatial scale along a 75 km transect in the Luangwa Valley, Zambia. The method offers a complementary approach to traditional compartmentalised modelling techniques, permitting incorporation of fine scale demographic data such as ethnicity, age and gender into the simulation...
December 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28018656/european-sea-bass-show-behavioural-resilience-to-near-future-ocean-acidification
#12
M Duteil, E C Pope, A Pérez-Escudero, G G de Polavieja, I Fürtbauer, M R Brown, A J King
Ocean acidification (OA)-caused by rising concentrations of carbon dioxide (CO2)-is thought to be a major threat to marine ecosystems and has been shown to induce behavioural alterations in fish. Here we show behavioural resilience to near-future OA in a commercially important and migratory marine finfish, the Sea bass (Dicentrarchus labrax). Sea bass were raised from eggs at 19°C in ambient or near-future OA (1000 µatm pCO2) conditions and n = 270 fish were observed 59-68 days post-hatch using automated tracking from video...
November 2016: Royal Society Open Science
https://www.readbyqxmd.com/read/28008825/simulating-the-elimination-of-sleeping-sickness-with-an-agent-based-model
#13
Pascal Grébaut, Killian Girardin, Valentine Fédérico, François Bousquet
Although Human African Trypanosomiasis is largely considered to be in the process of extinction today, the persistence of human and animal reservoirs, as well as the vector, necessitates a laborious elimination process. In this context, modeling could be an effective tool to evaluate the ability of different public health interventions to control the disease. Using the Cormas(®) system, we developed HATSim, an agent-based model capable of simulating the possible endemic evolutions of sleeping sickness and the ability of National Control Programs to eliminate the disease...
2016: Parasite: Journal de la Société Française de Parasitologie
https://www.readbyqxmd.com/read/28003529/managing-aquatic-parasites-for-reduced-drug-resistance-lessons-from-the-land
#14
Gregor F McEwan, Maya L Groner, Danielle L Burnett, Mark D Fast, Crawford W Revie
Atlantic salmon farming is one of the largest aquaculture industries in the world. A major problem in salmon farms is the sea louse ectoparasite Lepeophtheirus salmonis, which can cause stress, secondary infection and sometimes mortality in the salmon host. Sea lice have substantial impacts on farm economics and potentially nearby wild salmonid populations. The most common method of controlling sea louse infestations is application of chemicals. However, most farming regions worldwide have observed resistance to the small set of treatment chemicals that are available...
December 2016: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/27984581/cystisim-an-agent-based-model-for-taenia-solium-transmission-and-control
#15
Uffe Christian Braae, Brecht Devleesschauwer, Sarah Gabriël, Pierre Dorny, Niko Speybroeck, Pascal Magnussen, Paul Torgerson, Maria Vang Johansen
Taenia solium taeniosis/cysticercosis was declared eradicable by the International Task Force for Disease Eradication in 1993, but remains a neglected zoonosis. To assist in the attempt to regionally eliminate this parasite, we developed cystiSim, an agent-based model for T. solium transmission and control. The model was developed in R and available as an R package (http://cran.r-project.org/package=cystiSim). cystiSim was adapted to an observed setting using field data from Tanzania, but adaptable to other settings if necessary...
December 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27974578/variability-in-individual-activity-bursts-improves-ant-foraging-success
#16
Daniel Campos, Frederic Bartumeus, Vicenç Méndez, José S Andrade, Xavier Espadaler
Using experimental and computational methods, we study the role of behavioural variability in activity bursts (or temporal activity patterns) for individual and collective regulation of foraging in A. senilis ants. First, foraging experiments were carried out under special conditions (low densities of ants and food and absence of external cues or stimuli) where individual-based strategies are most prevalent. By using marked individuals and recording all foraging trajectories, we were then able to precisely quantify behavioural variability among individuals...
December 2016: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/27965914/computational-model-based-analysis-of-strategies-to-enhance-scaffold-vascularization
#17
Elif Seyma Bayrak, Banu Akar, Sami I Somo, Chenlin Lu, Nan Xiao, Eric M Brey, Ali Cinar
Stable and extensive blood vessel networks are required for cell function and survival in engineered tissues. A number of different strategies are currently being investigated to enhance biomaterial vascularization with screening primarily through extensive in vitro and in vivo experiments. In this article, we describe an agent-based model (ABM) developed to evaluate various strategies in silico, including design of optimal biomaterial structure, delivery of angiogenic factors, and application of prevascularized biomaterials...
2016: BioResearch Open Access
https://www.readbyqxmd.com/read/27956613/twenty-first-century-approaches-to-ancient-problems-climate-and-society
#18
Jade A d'Alpoim Guedes, Stefani A Crabtree, R Kyle Bocinsky, Timothy A Kohler
By documenting how humans adapted to changes in their environment that are often much greater than those experienced in the instrumental record, archaeology provides our only deep-time laboratory for highlighting the circumstances under which humans managed or failed to find to adaptive solutions to changing climate, not just over a few generations but over the longue durée Patterning between climate-mediated environmental change and change in human societies has, however, been murky because of low spatial and temporal resolution in available datasets, and because of failure to model the effects of climate change on local resources important to human societies...
December 20, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27941976/the-effect-of-contact-investigations-and-public-health-interventions-in-the-control-and-prevention-of-measles-transmission-a-simulation-study
#19
Wayne T A Enanoria, Fengchen Liu, Jennifer Zipprich, Kathleen Harriman, Sarah Ackley, Seth Blumberg, Lee Worden, Travis C Porco
BACKGROUND: Measles cases continue to occur despite its elimination status in the United States. To control transmission, public health officials confirm the measles diagnosis, identify close contacts of infectious cases, deliver public health interventions (i.e., post-exposure prophylaxis) among those who are eligible, and follow-up with the close contacts to determine overall health outcomes. A stochastic network simulation of measles contact tracing was conducted using existing agent-based modeling software and a synthetic population with high levels of immunity in order to estimate the impact of different interventions in controlling measles transmission...
2016: PloS One
https://www.readbyqxmd.com/read/27935954/normal-wound-healing-and-tumor-angiogenesis-as-a-game-of-competitive-inhibition
#20
Irina Kareva, Abdo Abou-Slaybi, Oliver Dodd, Olga Dashevsky, Giannoula Lakka Klement
Both normal wound healing and tumor angiogenesis are mitigated by the sequential, carefully orchestrated release of growth stimulators and inhibitors. These regulators are released from platelet clots formed at the sites of activated endothelium in a temporally and spatially controlled manner, and the order of their release depends on their affinity to glycosaminoglycans (GAG) such as heparan sulfate (HS) within the extracellular matrix, and platelet open canallicular system. The formation of vessel sprouts, triggered by angiogenesis regulating factors with lowest affinities for heparan sulfate (e...
2016: PloS One
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