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https://www.readbyqxmd.com/read/28803898/electrospun-fibrous-membranes-featuring-sustained-release-of-ibuprofen-reduce-adhesion-and-improve-neurological-function-following-lumbar-laminectomy
#1
Shen Liu, Guoqing Pan, Guangwang Liu, José das Neves, Sa Song, Shuai Chen, Bangjun Cheng, Zhiyong Sun, Bruno Sarmento, Wenguo Cui, Cunyi Fan
Electrospun fibrous membranes provide suitable physical anti-adhesion barriers for reducing tissue anti-adhesion following surgery. However, often during the biodegradation process, these barriers trigger inflammation and cause a foreign body reaction with subsequent decrease in anti-adhesion efficacy. Here, a facile strategy comprising the incorporation of ibuprofen (IBU) into implantable membranes and its sustained release was proposed in order to improve anti-adhesion effects and neurological outcomes, namely to prevent failed back surgery syndrome (FBSS)...
August 10, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28742245/patients-expectations-on-spinal-cord-stimulation-for-failed-back-surgery-syndrome-a-qualitative-exploration
#2
Dylan J H A Henssen, Nicole Scheepers, Erkan Kurt, Inge Arnts, Monique Steegers, Kris Vissers, Robert van Dongen, Yvonne Engels
BACKGROUND: Spinal cord stimulation (SCS) is an effective therapy to reduce pain in patients that suffer from failed back surgery syndrome (FBSS). In order to inform patients optimally prior to this therapy, knowing their expectations is crucial. METHODS: Thirteen patients suffering from FBSS and scheduled for SCS were interviewed, using a semi-structured protocol. Patients were interviewed either at home or at their treating hospital. Data from these interviews were analyzed using directed content analysis...
July 25, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/28662011/-the-assessment-of-the-impact-of-rehabilitation-on-the-pain-intensity-level-in-patients-with-herniated-nucleus-pulposus-of-the-intervertebral-disc
#3
Kamil Koszela, Sylwia Krukowska, Marta Woldańska-Okońska
Back disorders are very common phenomena in modern society. One of the methods of spinal pain treatment is performing surgery. Unfortunately, this method is not one hundred percent effective. Some patients show no improvement after surgery, the pain persists and even increases. In these cases, it is reasonable to use the term Failed Back Surgery Syndrome (FBSS), i.e. back pain syndrome after unsuccessful spine surgery. AIM: The aim of the study is to assess the impact of rehabilitation on the pain intensity level in patients with FBSS...
June 23, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28658870/failed-back-surgery-syndrome-evaluation-with-magnetic-resonance-imaging
#4
Peeyush Kumar Dhagat, Megha Jain, Satyendra Narayan Singh, Sumeet Arora, Kasukarthi Leelakanth
INTRODUCTION: Failed Back Surgery Syndrome (FBSS) is a generalized term used to describe varied spinal symptoms of patients who have had unsuccessful results after spinal surgery. The treatment of FBSS is challenging and varies from conservative management to reoperation. Imaging plays a crucial role in identifying the cause and helps to guide the appropriate therapy. Contrast enhanced Magnetic Resonance Imaging (MRI) with its superior resolution is the imaging modality of choice. AIM: To evaluate the spectrum of imaging findings on postoperative MRI in FBSS...
May 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28638269/clinical-insomnia-and-associated-factors-in-failed-back-surgery-syndrome-a-retrospective-cross-sectional-study
#5
Soon Young Yun, Do Heon Kim, Hae Yoon Do, Shin Hyung Kim
Background Insomnia frequently occurs to patients with persistent back pain. By worsening pain, mood, and physical functioning, insomnia could lead to the negative clinical consequences of patients with failed back surgery syndrome (FBSS). This retrospective and cross-sectional study aims to identify the risk factors associated with clinical insomnia in FBSS patients. Methods A total of 194 patients with FBSS, who met the study inclusion criteria, were included in this analysis. The Insomnia Severity Index (ISI) was utilized to ascertain the presence of clinical insomnia (ISI score ≥ 15)...
2017: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/28614539/effects-of-ozone-on-the-pain-and-disability-in-patients-with-failed-back-surgery-syndrome
#6
Danilo Costa Barbosa, Jairo Silva Dos Ângelos, Gleica Maria Josino de Macena, Francisco Nêuton de Oliveira Magalhães, Erich Talamoni Fonoff
Introduction: Low back pain is one of the painful disorders of higher prevalence. It has several etiologies and surgery may be indicated in the presence of neurological deficits or compression syndromes. However, in up to 40% of cases, patients develop worsening of pain and failed back surgery syndrome (FBSS), which is an important cause of chronic pain with high morbidity and disability. In the last two decades, ozone has been shown to be a new therapeutic option for FBSS due to its analgesic and anti-inflammatory properties...
April 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28603366/comparison-among-pain-depression-and-quality-of-life-in-cases-with-failed-back-surgery-syndrome-and-non-specific-chronic-back-pain
#7
Nilay Sahin, Ali Yavuz Karahan, Gul Devrimsel, Ilknur Albayrak Gezer
[Purpose] The aim of this study is to compare patients with failed back surgery syndrome (FBSS) with those with non-specific chronic back pain (NSCBP) in terms of pain, depression, and quality of life levels to explain the effects of surgery experience on low-back pain. [Subjects and Methods] A total of 50 patients with FBSS and 51 patients with NSCBP who consecutively applied to the outpatient clinic from September 2012 to April 2013 were included in the study. Patients completed questionnaires on demographics, body mass index, education level, work history, and pain duration (in months)...
May 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28544182/burst-or-high-frequency-10-khz-spinal-cord-stimulation-in-failed-back-surgery-syndrome-patients-with-predominant-back-pain-one-year-comparative-data
#8
Sajjad Muhammad, Sandra Roeske, Shafqat Rasul Chaudhry, Thomas Mehari Kinfe
OBJECTIVES: Burst and 10 kHz spinal cord stimulation (SCS) demonstrated improvement for failed back surgery syndrome (FBSS) with predominant, refractory back pain. Here, we report the long-term follow-up of a previously published study comparing the safety and efficacy of burst vs. 10 kHz SCS for predominant back pain (70% of global pain) of FBSS patients. METHODS: This comparative, observational study extended the follow-up period up to 20 months evaluating both SCS modalities...
May 24, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28507834/clinical-and-radiological-improvement-following-ozone-disc-nucleolysis-a-case-report
#9
Sharad Ghatge, Pranav D Modi, Dhaval B Modi
The results of traditional open surgery for herniated intervertebral disc are often limited by complications and failed back surgery syndrome (FBSS). Over the past few decades, a considerable amount of research has been done in the field of minimally invasive procedures as a treatment option for herniated intervertebral disc disease. Ozone disc nucleolysis is one such procedure which has results equal to or better than traditional surgery with virtually no complications. A 27-year-old post-partum female presented to the clinic with acute onset of severe lower back pain radiating to the left lower limb for one month...
April 13, 2017: Curēus
https://www.readbyqxmd.com/read/28505029/treatment-options-for-failed-back-surgery-syndrome-patients-with-refractory-chronic-pain-an-evidence-based-approach
#10
Kasra Amirdelfan, Lynn Webster, Lawrence Poree, Vishad Sukul, Porter McRoberts
STUDY DESIGN: A significant number of lumbar postsurgical patients continue to suffer persistent pain and limited function and are termed to have "Failed back surgery syndrome" (FBSS). This review evaluates clinical trial data for the treatment of FBSS patients. OBJECTIVE: Using an evidence-based approach to evaluate FBSS treatments will assist clinicians in choosing the most effective options for FBSS patients. Furthermore, reducing the utilization of less effective therapies may result in substantial financial savings for this patient population...
July 15, 2017: Spine
https://www.readbyqxmd.com/read/28486758/stimulation-of-the-l2-l3-dorsal-root-ganglia-induces-effective-pain-relief-in-the-low-back
#11
Frank Huygen, Liong Liem, William Cusack, Jeffery Kramer
INTRODUCTION: Chronic low back pain affects millions of people worldwide and can arise through a variety of clinical origins. In the case of Failed Back Surgery Syndrome (FBSS), previous surgical procedures can contribute to low back pain that is often unresponsive to intervention. Although spinal cord stimulation can be an effective treatment modality, it does not provide sufficient pain relief for some intractable cases. Recently, alternative neuromodulation options have been developed, including dorsal root ganglion (DRG) stimulation...
May 9, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/28464357/effect-of-multicolumn-lead-spinal-cord-stimulation-on-low-back-pain-in-failed-back-surgery-patients-a-three-year-follow-up
#12
Thibault Yves Remacle, Vincent Luce Bonhomme, Henri-Jean Paul Renwart, Jean Michel Remacle
OBJECTIVES: Spinal cord stimulation (SCS) remains poorly efficient at reducing back pain in failed back surgery syndrome (FBSS) patients. We aimed at determining whether a new multicolumn lead SCS technique was efficient at durably reducing their leg (LP) and back (BP) pain. MATERIALS AND METHODS: Sixty-two consecutive refractory FBSS patients received multicolumn SCS. Visual analogue scale (VAS) self-evaluation of BP, LP, and limitation of daily activity (LAD) were recorded preoperatively and at 2, 6, 12, 24, and 36 months after surgery...
May 2, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28441313/clinical-evidence-for-spinal-cord-stimulation-for-failed-back-surgery-syndrome-fbss-systematic-review
#13
Leonardo Kapural, Erika Peterson, David A Provenzano, Peter Staats
STUDY DESIGN: A systematic review. OBJECTIVE: A systematic literature review of the clinical data from prospective studies was undertaken to assess the efficacy of spinal cord stimulation (SCS) in the treatment of failed back surgery syndrome (FBSS) in adults. SUMMARY OF BACKGROUND DATA: For patients with unrelenting back pain due to mechanical instability of the spine, degenerative disc disease, spinal injury, or deformity, spinal surgery is a well-accepted treatment option; however, even after surgical intervention, many patients continue to experience chronic back pain that can be notoriously difficult to treat...
July 15, 2017: Spine
https://www.readbyqxmd.com/read/28435318/prevalence-characteristics-and-burden-of-failed-back-surgery-syndrome-the-influence-of-various-residual-symptoms-on-patient-satisfaction-and-quality-of-life-as-assessed-by-a-nationwide-internet-survey-in-japan
#14
Shinsuke Inoue, Mitsuhiro Kamiya, Makoto Nishihara, Young-Chang P Arai, Tatsunori Ikemoto, Takahiro Ushida
We conducted a cross-sectional, Internet-based survey with a nationally representative sample of Japanese adults to assess the prevalence and characteristics of failed back surgery syndrome (FBSS). Data regarding the residual symptoms and patient satisfaction from an online survey of 1842 lumbar surgery patients revealed the prevalence of FBSS to be 20.6% (95% confidence interval [CI], 18.8-22.6). The prevalence of low back pain, dull ache, numbness, cold sensations, and paresthesia after surgery was 94.0%, 71...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28322477/impact-of-insurance-provider-on-overall-costs-in-failed-back-surgery-syndrome-a-cost-study-of-122-827-patients
#15
Aladine A Elsamadicy, Samuel Harrison Farber, Siyun Yang, Syed Mohammed Qasim Hussaini, Kelly R Murphy, Amanda Sergesketter, Carter M Suryadevara, Promila Pagadala, Beth Parente, Jichun Xie, Shivanand P Lad
OBJECTIVES: Failed back surgery syndrome (FBSS) affects 40% of patients following spine surgery with estimated costs of $20 billion to the US health care system. The aim of this study was to assess the cost differences across the different insurance providers for FBSS patients. METHODS: A retrospective longitudinal study was performed using the Truven MarketScan(®) database to identify FBSS patients from 2001 to 2012. Patients were grouped into Commercial, Medicaid, or Medicare cohorts...
June 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28194840/burst-spinal-cord-stimulation-increases-peripheral-antineuroinflammatory-interleukin-10-levels-in-failed-back-surgery-syndrome-patients-with-predominant-back-pain
#16
Thomas M Kinfe, Sajjad Muhammad, Carolina Link, Sandra Roeske, Shafqat R Chaudhry, Thomas L Yearwood
OBJECTIVES: Burst spinal cord stimulation (SCS) has been reported to reduce back pain and improve functional capacity in Failed Back Surgery Syndrome (FBSS). However, its mechanism of action is not completely understood. Systemic circulating cytokines have been associated with the development of chronic back pain. METHODS: This prospective, feasibility study enrolled 12 refractory FBSS patients with predominant back pain (70% of overall pain) suitable for Burst SCS...
February 13, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28132158/evaluation-of-spinal-cord-stimulation-on-the-symptoms-of-anxiety-and-depression-and-pain-intensity-in-patients-with-failed-back-surgery-syndrome
#17
L P Robb, J M Cooney, C R McCrory
BACKGROUND: Spinal cord stimulation (SCS) is now established as the primary treatment for failed back surgery syndrome (FBSS). Commonly, patients with chronic pain and FBSS often report symptoms of anxiety and depression resulting from this condition. These factors can modulate and amplify the pain experience, therefore, further challenging treatment success. AIMS: This study examined the efficacy of SCS on alleviating the symptoms of anxiety and depression associated with chronic pain as well as pain intensity in a group of patients with FBSS...
January 28, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28129399/long-term-course-of-failed-back-surgery-syndrome-fbss-patients-receiving-integrative-korean-medicine-treatment-a-1-year-prospective-observational-multicenter-study
#18
Jinho Lee, Joon-Shik Shin, Yoon Jae Lee, Me-Riong Kim, Areum Choi, Jun-Hwan Lee, Kyung-Min Shin, Byung-Cheul Shin, Jae-Heung Cho, In-Hyuk Ha
BACKGROUND: With increase of spine surgeries, failed back surgery syndrome (FBSS) prevalence is also rising. While complementary and alternative medicine (CAM) is commonly used for low back pain (LBP), there are no studies reporting use of integrative Korean medicine in FBSS patients. METHODS: Patients with pain continuing after back surgery or recurring within 1 year and visual analogue scale (VAS) of LBP or leg pain of ≥6 (total n = 120) were recruited at 2 hospital sites from November 2011 to September 2014...
2017: PloS One
https://www.readbyqxmd.com/read/28120049/update-on-mechanism-and-therapeutic-implications-of-spinal-cord-stimulation-and-cerebral-hemodynamics-a-narrative-review
#19
Elisabetta Peppucci, Rina Di Bonaventura, Vincenzo Esposito, Jun Zhong, Gerardo Iacopino, Giuseppe Barbagallo, Massimiliano Visocchi
Spinal cord stimulation (SCS) is well known for its early role in the management of chronic pain, mainly failed back surgery syndrome (FBSS), spasticity, and bowel and bladder dysfunction. In more recent years, SCS has been proposed for patients suffering from refractory angina or peripheral vasculopathies in order to gain symptom relief, thus indicating some hemodynamic effect on the peripheral circulation. Taking into account this scientific observation, since the late1980s, researchers have started to investigate the potential effect of SCS on cerebral blood flow (CBF) regulation and its possible application in certain pathological settings dealing with vascular pattern dysfunction, such as ischemia, subarachnoid hemorrhage, head trauma, and brain tumors...
2017: Acta Neurochirurgica. Supplement
https://www.readbyqxmd.com/read/28072795/treatment-outcomes-for-patients-with-failed-back-surgery
#20
REVIEW
Jae Hwan Cho, Jae Hyup Lee, Kwang Sup Song, Jae-Young Hong, Yoon-Suk Joo, Dong-Ho Lee, Chang Ju Hwang, Choon Sung Lee
BACKGROUND: Failed back surgery syndrome (FBSS) is a frequently encountered disease entity following lumbar spinal surgery. Although many plausible reasons have been investigated, the exact pathophysiology remains unknown. Various medications, reoperations, interventions such as spinal cord stimulation, epidural adhesiolysis or epidural injection, exercise therapy, and psychotherapy have been suggested treatment options. However, the evidence of the clinical outcome for each treatment has not been clearly determined...
January 2017: Pain Physician
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