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https://www.readbyqxmd.com/read/28805620/ex-utero-intrapartum-treatment-for-extremely-low-birth-weight-neonates-requiring-resuscitation-at-birth
#1
Tai-Ho Hung, Ting-Xuan Huang, T'sang-T'ang Hsieh
OBJECTIVE: Difficulties often encountered during intubation in extremely low birth-weight (ELBW) neonates requiring resuscitation at birth because of the smaller airway and the pressure from the limited number of attempts before hemodynamic instability occurs. CASE REPORT: We evaluated two pregnant women at 26 weeks of gestation with premature rupture of membranes and evidence of chorioamnionitis and applied the concept of ex utero intrapartum treatment, which involved delaying cord clamping (DCC) after establishing a secured airway with adequate ventilation during cesarean delivery...
August 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28800210/rates-of-early-intervention-services-in-children-born-extremely-preterm-extremely-low-birthweight
#2
Ianthe S Mills, Lex W Doyle, Jeanie Ly Cheong, Gehan Roberts
AIM: To determine the rates of early intervention (EI) service use in extremely preterm (EP, <28 weeks' gestation) or extremely low birthweight (ELBW, <1000 g) infants between 1991 and 2013, and identify biological or socio-economic factors associated with receiving EI. METHODS: Participants comprised consecutive EP or ELBW survivors born in 1991-1992, 1997 or 2005 in Victoria, Australia, and randomly selected, matched term-born controls. The main outcome measure was parent-reported EI participation up to 8 years of age...
August 11, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28776722/exposure-to-overprotective-parenting-and-psychopathology-in-extremely-low-birth-weight-survivors
#3
K L Day, K G Dobson, L A Schmidt, M A Ferro, S Saigal, M H Boyle, R J Van Lieshout
BACKGROUND: Extremely low birth weight (ELBW; <1,000 g) infants are the most vulnerable babies and are at higher risk for experiencing overprotective (i.e., controlling and intrusive) parenting, which is hypothesized to contribute to the risk for mental disorders. Despite the increased risk for anxiety disorders and decreased risk for alcohol or substance use disorders seen in ELBW survivors, no research has examined the impact of parenting. This study investigated if overprotective parenting mediates links between ELBW birth status and psychiatric disorders in adulthood...
August 4, 2017: Child: Care, Health and Development
https://www.readbyqxmd.com/read/28774507/clinical-factors-associated-with-in-hospital-death-in-pediatric-surgical-patients-admitted-to-the-neonatal-intensive-care-unit-a-15-year-single-tertiary-center-experience
#4
Kohei Otake, Keiichi Uchida, Michiko Kubo, Akira Yamamoto, Yuka Nagano, Ryo Uratani, Kiyoshi Hashimoto, Kohei Matsushita, Mikihiro Inoue, Hirofumi Sawada, Masato Kusunoki
BACKGROUND/PURPOSE: The purpose of this study was to explore clinical characteristics and primary surgical diagnoses associated with in-hospital death in pediatric surgical patients admitted to the neonatal intensive care unit (NICU) of a tertiary hospital. METHODS: This retrospective study includes all patients admitted to our NICU for pediatric surgical diseases between January 2001 and December 2015. Univariate and multivariate binary logistic regression were performed to assess independent factors associated with in-hospital death...
July 15, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28774357/-effect-of-extensively-hydrolyzed-formula-on-growth-and-development-of-infants-with-very-extremely-low-birth-weight
#5
Chun-Yan Gu, Hui-Fen Jiang, Jin-Xiu Wang
OBJECTIVE: To study the effect of extensively hydrolyzed formula on the growth and development in very low birth weight (VLBW) and extremely low birth weight (ELBW) infants. METHODS: A total of 375 VLBW or ELBW infants were enrolled and divided into an observation group (187 infants) and a control group (188 infants) using a random number table. The infants in the observation group were given extensively hydrolyzed formula, and when the amount of extensively hydrolyzed formula reached 10 mL/time, it was changed to the standard formula for preterm infants...
August 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/28768269/a-potential-role-for-the-nod1-variant-rs6958571-in-gram-positive-blood-stream-infection-in-elbw-infants
#6
Venkatesh Sampath, Neil Mulrooney, Aloka L Patel, Jonathan Cohen, Liyun Zhang, Jeffery Garland, Pascal M Lavoie, John Dagle, Pippa Simpson
BACKGROUND: The genetic basis of sepsis susceptibility in preterm infants remains understudied. Herein, we investigated the nucleotide binding-oligomerization domain (NOD)-like receptor (NLR) family of immune receptors as putative loci for preterm sepsis susceptibility. OBJECTIVE: To determine whether single nucleotide polymorphisms (SNPs) in NLR genes are associated with blood stream infections (BSI) in premature infants. METHODS: An international cohort of infants with gestational age (GA) <35 weeks were genotyped for SNPs in the ATG16L1, CARD8, NLRP3, NOD2, and NOD1 genes...
August 3, 2017: Neonatology
https://www.readbyqxmd.com/read/28756708/biomarkers-of-necrotizing-enterocolitis-a-review-of-literature
#7
Bhawan Deep Garg, Deepak Sharma, Anju Bansal
Necrotizing enterocolitis (NEC) is among the most serious gastrointestinal emergency in very low birth weight (VLBW), extremely low birth weight (ELBW) and extremely low gestational age neonates (ELGAN), affecting 7-14% of these neonates. Despite extensive research, the underlying aetiology of NEC still remains blurred. Due to high mortality, morbidity and its delayed presentation, early detection of NEC is considered to be lifesaving. A number of biomarkers has been studied for early detection and prediction of severity of NEC but till date, no ideal marker have been discovered...
July 31, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28752669/behaviour-of-4-to-5-year-old-nondisabled-elbw-children-outcomes-following-group-based-physiotherapy-intervention
#8
L Brown, Y R Burns, P Watter, P H Gray, K S Gibbons
BACKGROUND: Extreme prematurity or extremely low birth weight (ELBW) can adversely affect behaviour. Nondisabled ELBW children are at risk of behavioural problems, which may become a particular concern after commencement of formal education. This study explored the frequency of behavioural and emotional problems amongst nondisabled ELBW children at 4 to 5 years of age and whether intervention had a positive influence on behaviour. The relationship between behaviour, gender, and other areas of performance at 5 years was explored...
July 28, 2017: Child: Care, Health and Development
https://www.readbyqxmd.com/read/28750269/a-comparative-analysis-of-ante-and-postnatal-clinical-characteristics-of-extremely-premature-neonates-suffering-from-refractory-and-non-refractory-hypotension-is-early-clinical-differentiation-possible
#9
Rita P Verma, Shaeequa Dasnadi, Yuan Zhao, Hegang H Chen
BACKGROUND: About 25% of hypotensive ELBW infants are refractory to intravascular volume expansion and inotropic drugs (VI) and require hydrocortisone (HC). Such neonates suffer from complications of prolonged hypotension and extended therapy with VI. ELBW infants with refractory hypotension (RH) are clinically and biochemically indistinguishable from those who respond to VI. OBJECTIVE: Early identification and differentiation of ELBW infants susceptible to steroid dependent hypotension from those who respond to inotropic medications...
July 24, 2017: Early Human Development
https://www.readbyqxmd.com/read/28744798/ultrasound-guided-hydrostatic-enema-for-meconium-obstruction-in-extremely-low-birth-weight-infants-a-preliminary-report
#10
Tatsuo Nakaoka, Satomi Nishimoto, Yukino Tsukazaki, Kenji Santo, Atsushi Higashio, Masafumi Kamiyama, Shuichiro Uehara, Akihiro Yoneda, Yuko Tanaka, Hiroyuki Ichiba
Meconium obstruction (MO) in extremely low birth weight (ELBW) infants is a challenging disease to treat. We performed ultrasound-guided hydrostatic enema on six ELBW infants diagnosed with MO. We consider this procedure to be safe and effective, and recommend it as a treatment for MO in ELBW infants.
July 25, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28727140/respiratory-sinus-arrhythmia-in-the-fourth-decade-of-life-depends-on-birth-weight-and-the-drd4-gene-implications-for-understanding-the-development-of-emotion-regulation
#11
Calan Savoy, Karen J Mathewson, Louis A Schmidt, Katherine M Morrison, John E Krzeczkowski, Ryan J Van Lieshout
INTRODUCTION: The long allele of the DRD4 gene can confer different behavioral and emotional phenotypes depending upon environmental exposure, although the physiological changes underlying these phenotypes are not fully known. We sought to extend this work by assessing the interaction of the DRD4 gene and exposure to perinatal adversity (indexed by extremely low birth weight [ELBW]) on resting respiratory sinus arrhythmia (RSA), a neurophysiological measure of emotion regulation, in adulthood...
July 20, 2017: Developmental Psychobiology
https://www.readbyqxmd.com/read/28721812/update-on-phototherapy-in-jaundiced-neonates
#12
Finn Ebbesen, Thor Willy Ruud Hansen, M Jeffrey Maisels
BACKGROUND: Even relatively low serum bilirubin concentrations can cause neurodevelopmental impairment in extremely low birth weight (EBWL) infants, while sequelae from hyperbilirubinemia in late preterm and term infants are rare and occur only at very high serum bilirubin lev-els. Phototherapy is the current treatment of choice. OBJECTIVE: To present an update on the most important issues involved in phototherapy for jaundiced infants. RESULTS: Light absorption by bilirubin in the skin transforms the native Z,Z-bilirubin to conformational photoisomers Z,E-bilirubin and E,Z-bilirubin and structural photoisomers E,Z-lumirubin and E,E-lumirubin...
July 18, 2017: Current Pediatric Reviews
https://www.readbyqxmd.com/read/28711895/-the-dynamics-of-the-incidence-of-intraventricular-hemorrhages-and-their-outcomes-among-prematurely-born-children-of-the-poltava-region-in-2007-2016
#13
Елена А Калюжка, Наталия С Артемова, Наталия И Гасюк, Светлана Н Цвиренко, Валерий И Похилько
INTRODUCTION: Over the past decade, with the increase in the number of prematurely born babies with very-low-body-weight (VLBW) at birth, the number of intraventricular hemorrhages (IVH), including severe, increases, which leads to an increase in mortality and an increase in the number of posthemorrhagic hydrocephalus (PHH). AIM: To establish epidemiological trends in the IVH frequency, as well as their outcomes (PHH, mortality), among prematurely born children of the Poltava region during 2007-2016...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28674637/recurrent-staphylococcal-scalded-skin-syndrome-in-an-extremely-low-birth-weight-neonate
#14
Jennifer Davidson, Samantha Polly, Peter J Hayes, Kristopher R Fisher, Ajay J Talati, Tejesh Patel
Staphylococcal scalded skin syndrome (SSSS) in premature infants is a rare condition. We present SSSS in an extremely low-birth-weight (ELBW) infant with recurrent and confirmed bacterial sepsis. We present it to emphasize the importance for clinicians to not only recognize the clinical manifestations of SSSS, but also the need to closely monitor infants, especially very low-birth-weight (VLBW) and ELBW infants with SSSS for recurrence and bacterial sepsis. SSSS in preterm infants is a potentially lethal condition and early recognition and appropriate supportive care could be life-saving...
April 2017: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/28662303/measuring-birth-outcomes-in-new-york-state-using-a-multidimensional-approach
#15
Rosa Darling, A Serdar Atav
OBJECTIVE: Poorer birth outcomes in the United States and New York State (NYS) remain a significant public health concern. The objectives of this study were to assess the effect of common and unique demographic, socioeconomic, and health services predictors on low birth weight (LBW), moderately LBW, very low birth weight (VLBW), and extremely low birth weight (ELBW) in NYS counties and to recommend policies that address unique differences at the county level. METHODS: Secondary data were collected for each of the 62 counties in NYS...
June 29, 2017: Nursing Forum
https://www.readbyqxmd.com/read/28658720/enteral-lactoferrin-supplementation-for-prevention-of-sepsis-and-necrotizing-enterocolitis-in-preterm-infants
#16
REVIEW
Mohan Pammi, Gautham Suresh
BACKGROUND: Lactoferrin, a normal component of human colostrum and milk, can enhance host defenses and may be effective for prevention of sepsis and necrotizing enterocolitis (NEC) in preterm neonates. OBJECTIVES: Primary objective 1. To assess the safety and effectiveness of lactoferrin supplementation to enteral feeds for prevention of sepsis and NEC in preterm neonates Secondary objectives 1. To determine the effects of lactoferrin supplementation to enteral feeds to prevent neonatal sepsis and/or NEC on duration of positive-pressure ventilation, development of chronic lung disease (CLD) or periventricular leukomalacia (PVL), length of hospital stay to discharge among survivors, and adverse neurological outcomes at two years of age or later2...
June 28, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28616708/comparison-of-different-definitions-of-acute-kidney-injury-in-extremely-low-birth-weight-infants
#17
Vikas Chowdhary, Ramya Vajpeyajula, Mohit Jain, Syeda Maqsood, Rupesh Raina, Deepak Kumar, Maroun J Mhanna
BACKGROUND: The definition of acute kidney injury (AKI) has evolved over the years, and three definitions have been adapted including pediatric risk injury failure, loss of kidney function (pRIFLE), Acute Kidney Injury Network (AKIN), and Neonatal Modified Kidney Disease Improving Global Outcomes (KDIGO). We sought to report the prevalence and outcome of (AKI) according to the three existing definitions in extremely low birth weight (ELBW) infants. METHODS: In a retrospective cohort study, medical records of all ELBW infants (<1000 g) admitted to our neonatal intensive care unit (NICU) between Jan 2002 and Dec 2011 were reviewed...
June 14, 2017: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/28615304/ibuprofen-exposure-in-early-neonatal-life-does-not-affect-renal-function-in-young-adolescence
#18
Anke Raaijmakers, Zhen-Yu Zhang, Elena Levtchenko, Sinno Hp Simons, Nicholas Cauwenberghs, Lambertus P van den Heuvel, Lotte Jacobs, Jan A Staessen, Karel Allegaert
INTRODUCTION: Ibuprofen exposure results in acute transient renal dysfunction in preterm neonates, but we are unaware of data on long-term renal safety. METHODS: In a previously studied cohort of extreme low birth weight (ELBW, <1000 g) cases, the PREMATurity as predictor of children's Cardiovascular-renal Health study generated data on renal function (renal length, estimated glomerular filtration rate based on cystatin C (eGFRcysC) at the age of 11 years. This data set in 93 ELBW cases may also generate data on long-term drug safety on ibuprofen...
June 14, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28614987/role-of-amino-acid-supplementation-in-prevention-of-necrotizing-enterocolitis-in-preterm-neonates-a-review-of-current-evidences
#19
Bhawan Deep Garg, Nandkishor S Kabra
BACKGROUND: Necrotizing enterocolitis (NEC) is one of the most common acute and fatal gastrointestinal emergency in very low birth weight (VLBW) preterm neonates with mortality range from 15-30%. NEC is likely due to multifactorial process such as oxidative injury, ischemic necrosis and over reactive inflammatory response to intestinal microbes. AIMS: To evaluate the role of amino acid supplementation for reduction of neonatal NEC in preterm neonates. METHOD: The literature search was done for various randomized control trial (RCT) by searching the Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, EMBASE, Web of Science, Scopus, Index Copernicus, African Index Medicus (AIM), Thomson Reuters (ESCI), Chemical Abstracts Service (CAS) and other data base...
June 14, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28585081/mental-health-assessed-by-the-strengths-and-difficulties-questionnaire-for-children-born-extremely-preterm-without-severe-disabilities-at-11%C3%A2-years-of-age-a-norwegian-national-population-based-study
#20
Silje Katrine Elgen Fevang, Mari Hysing, Kristian Sommerfelt, Irene Elgen
The aims were to investigate mental health problems with the Strength and Difficulties Questionnaire (SDQ) in children born extremely preterm/extremely low birth weight (EP/ELBW) without severe disabilities compared to controls, and to identify peri-, or neonatal factors possibly predicting later mental health problems. A national Norwegian cohort of 11-year-old EP/ELBW children, excluding those with intellectual disabilities, non-ambulatory cerebral palsy, blindness and/or deafness, was assessed. Parents and teachers completed the SDQ...
June 5, 2017: European Child & Adolescent Psychiatry
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