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https://www.readbyqxmd.com/read/29470183/the-central-effects-of-androgenic-anabolic-steroid-use
#1
Marek Mędraś, Anna Brona, Paweł Jóźków
: Millions of men use androgenic-anabolic steroids (AAS) to stimulate muscle growth and improve physical appearance. Although 1 out of 3 people who uses androgenic-anabolic steroids develops a steroid use disorder, the effects of the drugs on the central nervous system and the psyche are still not well understood. Although most addictive substances improve mood immediately after administration, AAS exert less pronounced euphoric effects. Instead, they are primarily taken for the delayed gratification of increased muscle mass...
February 21, 2018: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/29470092/the-stroop-test-as-a-measure-of-performance-validity-in-adults-clinically-referred-for-neuropsychological-assessment
#2
Laszlo A Erdodi, Sanya Sagar, Kristian Seke, Brandon G Zuccato, Eben S Schwartz, Robert M Roth
This study was designed to develop performance validity indicators embedded within the Delis-Kaplan Executive Function Systems (D-KEFS) version of the Stroop task. Archival data from a mixed clinical sample of 132 patients (50% male; MAge = 43.4; MEducation = 14.1) clinically referred for neuropsychological assessment were analyzed. Criterion measures included the Warrington Recognition Memory Test-Words and 2 composites based on several independent validity indicators. An age-corrected scaled score ≤6 on any of the 4 trials reliably differentiated psychometrically defined credible and noncredible response sets with high specificity (...
February 22, 2018: Psychological Assessment
https://www.readbyqxmd.com/read/29468387/assessing-the-equivalence-of-web-based-and-paper-and-pencil-questionnaires-using-differential-item-and-test-functioning-dif-and-dtf-analysis-a-case-of-the-four-dimensional-symptom-questionnaire-4dsq
#3
Berend Terluin, Evelien P M Brouwers, Miquelle A G Marchand, Henrica C W de Vet
PURPOSE: Many paper-and-pencil (P&P) questionnaires have been migrated to electronic platforms. Differential item and test functioning (DIF and DTF) analysis constitutes a superior research design to assess measurement equivalence across modes of administration. The purpose of this study was to demonstrate an item response theory (IRT)-based DIF and DTF analysis to assess the measurement equivalence of a Web-based version and the original P&P format of the Four-Dimensional Symptom Questionnaire (4DSQ), measuring distress, depression, anxiety, and somatization...
February 21, 2018: Quality of Life Research
https://www.readbyqxmd.com/read/29462181/association-between-somatic-symptom-burden-and-health-related-quality-of-life-in-people-with-chronic-low-back-pain
#4
Tomoko Fujii, Hiroyuki Oka, Junji Katsuhira, Juichi Tonosu, Satoshi Kasahara, Sakae Tanaka, Ko Matsudaira
Depression is a relevant risk factor for low back pain and is associated with the outcomes of low back pain. Depression also often overlaps with somatisation. As previous studies have suggested that somatisation or a higher somatic symptom burden has a role in the outcomes of low back pain, the aim of the present cross-sectional study was to examine whether somatic symptom burden was associated with health-related quality of life in individuals with chronic low back pain independent of depression. We analyzed internet survey data on physical and mental health in Japanese adults aged 20-64 years with chronic low back pain (n = 3,100)...
2018: PloS One
https://www.readbyqxmd.com/read/29458280/depressive-symptoms-are-associated-with-color-vision-but-not-olfactory-function-in-patients-with-parkinson-s-disease
#5
Da-Ke Li, Feng-Tao Liu, Kui Chen, Lu-Lu Bu, Ke Yang, Chen Chen, Zhen-Yang Liu, Yi-Lin Tang, Jue Zhao, Yi-Min Sun, Jian Wang, Jian-Jun Wu
Depressive symptoms and sensory dysfunction, such as reduction in visual and olfactory function, are common in Parkinson's disease (PD). Previous studies have suggested that depressive symptoms are associated with visual impairments and potentially with hyposmia in several types of mood disorders. However, the relationship between depressive symptoms and sensory dysfunction remains unclear in PD. To examine the association of depressive symptoms with color vision and olfactory function in PD, the authors conducted a cross-sectional study in 159 patients with PD...
February 20, 2018: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/29458245/impact-of-sleep-quality-on-clinical-features-of-primary-sj%C3%A3-gren-s-syndrome
#6
Sang Wan Chung, Jaehyung Hur, You-Jung Ha, Eun Ha Kang, Joon Young Hyon, Hyo-Jung Lee, Yeong Wook Song, Yun Jong Lee
Background/Aims: This study aimed to investigate the inf luence of poor sleep quality on clinical features of primary Sjögren's syndrome (pSS). Methods: Sleep quality was cross-sectionally assessed using the Pittsburgh Sleep Quality Index (PSQI), and demographic, clinical, and laboratory data were collected from 115 Korean patients with pSS. The patients completed questionnaires on the European League Against Rheumatism (EULAR) SS Patient Reported Index (ESSPRI), quality of life (EuroQOL five dimensions questionnaire [EQ-5D]), fatigue (fatigue severity score [FSS]), and depression (Beck Depression Inventory [BDI] II])...
February 20, 2018: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29457522/a-high-prevalence-of-tmd-is-related-to-somatic-awareness-and-pain-intensity-among-healthy-dental-students
#7
Anna Lövgren, Catharina Österlund, Aurelija Ilgunas, Ewa Lampa, Fredrik Hellström
OBJECTIVE: Dental students have been identified as a group with high risks of developing both temporomandibular disorders (TMD) and psychosocial conditions. Our primary aim was to evaluate the cross-sectional prevalence of TMD diagnoses, as defined in the Diagnostic Criteria (DC)/TMD, among dental students. The secondary aim was to evaluate the prevalence and association of behavioural and psychosocial factors in relation to DC/TMD diagnoses. MATERIALS AND METHODS: The study was conducted among undergraduate dental students during the second semester of their third year at the Department of Odontology, Medical Faculty, Umeå University, Sweden...
February 18, 2018: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/29457375/evidence-for-alternate-modes-of-b-cell-activation-involving-fab-acquired-n-glycosylations-in-antibody-secreting-cells-infiltrating-the-labial-salivary-glands-of-sj%C3%A3-gren-s-syndrome-patients
#8
Kristi A Koelsch, Joshua Cavett, Kenneth Smith, Jacen S Moore, Sylvain D Lehoux, Nan Jia, Tim Mather, Syed M S Quadri, Astrid Rasmussen, C Erick Kaufman, David M Lewis, Lida Radfar, Teresa A Scordino, Christopher J Lessard, Biji T Kurien, Richard D Cummings, Judith A James, Kathy L Sivils, A Darise Farris, R Hal Scofield
OBJECTIVE: To better understand the role of B cells, potential mechanisms for their aberrant activation, and the production of autoantibodies in the pathogenesis of Sjögren's Syndrome (SS), we explored selection pressures and N-glycosylation acquired by somatic mutation (acN-glyc) in the immunoglobulin (Ig) variable regions (V-regions) of antibody secreting cells (ASCs) isolated from the minor salivary glands of SS patients and non-SS controls with sicca symptoms. METHODS: We report a novel method to produce and characterize recombinant monoclonal antibodies (mAbs) from SS patient and control labial salivary gland single-cell sorted ASC infiltrates that can be utilized to concurrently probe any other expressed genes...
February 18, 2018: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29457326/associations-between-adolescent-risk-for-restrictive-disordered-eating-and-long-term-outcomes-related-to-somatic-symptoms-body-mass-index-and-poor-well-being
#9
Evelina Landstedt, Anne Hammarström, A Kate Fairweather-Schmidt, Tracey Wade
OBJECTIVE: To date, no longitudinal, community-based studies have examined the association between disordered eating emerging in adolescence and long-term physical well-being. This study sought to explore the longitudinal associations between risk for restrictive disordered eating (DE-R; those not presenting with binge-purge symptoms) in adolescence and trajectories of functional somatic symptoms (FSS) and body mass index (BMI), and several indicators of poor physical well-being across early- to mid-adulthood, including medication, number of doctor visits, and sick leave...
February 18, 2018: British Journal of Health Psychology
https://www.readbyqxmd.com/read/29455899/perception-of-induced-dyspnea-in-fibromyalgia-and-chronic-fatigue-syndrome
#10
Maaike Van Den Houte, Katleen Bogaerts, Ilse Van Diest, Jozef De Bie, Philippe Persoons, Lukas Van Oudenhove, Omer Van den Bergh
OBJECTIVE: Dyspnea perception is distorted in patients with medically unexplained dyspnea. The goals of this study were 1) to replicate these results in patients with fibromyalgia and/or chronic fatigue syndrome (CFS), and 2) to investigate predictors of distorted symptom perception within the patient group, with a focus on negative affectivity (NA), psychiatric comorbidity and somatic symptom severity. METHODS: Seventy-three patients diagnosed with fibromyalgia and/or CFS and 38 healthy controls (HC) completed a rebreathing paradigm, consisting of a baseline (60s of room air), a rebreathing phase (150s, gradually increasing ventilation, partial pressure of CO2 in the blood, and self-reported dyspnea), and a recovery phase (150s of room air)...
March 2018: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29455021/effect-of-dopamine-receptor-d4-drd4-haplotypes-on-general-psychopathology-in-patients-with-eating-disorders
#11
Guillermo Gervasini, Luz M González, Carmen Gamero-Villarroel, Sonia Mota-Zamorano, Juan Antonio Carrillo, Isalud Flores, Angustias Garcia-Herráiz
Among the many candidate genes analyzed in eating disorder (ED) patients, those involved in dopaminergic functions may be of special relevance, as dopamine is known to play a significant role in feeding behavior, the distortion of body image, hyperactivity and reward and reinforcement processes. We aimed to determine the effect of functional polymorphisms and haplotypes in the Dopamine Receptor D4 (DRD4) gene on general psychopathological symptoms in ED patients. Two-hundred-and-seventy-three ED patients [199 with Anorexia Nervosa (AN) and 74 with Bulimia Nervosa (BN)] completed the SCL-90R inventory and were genotyped for four functional, clinically relevant DRD4 polymorphisms: three variants in the promoter region [120-bp tandem repeat (TR, long vs...
February 15, 2018: Gene
https://www.readbyqxmd.com/read/29453384/longitudinal-impact-of-ibs-type-symptoms-on-disease-activity-healthcare-utilization-psychological-health-and-quality-of-life-in-inflammatory-bowel-disease
#12
David J Gracie, P John Hamlin, Alexander C Ford
OBJECTIVES: The impact of irritable bowel syndrome (IBS)-type symptoms on the natural history of inflammatory bowel disease (IBD) is uncertain. We aimed to address this in a longitudinal study of secondary care patients. METHODS: Longitudinal disease activity was defined by disease flare, escalation of medical therapy, hospitalization, or intestinal resection. The number of investigations performed and clinics attended determined healthcare utilization. Psychological well-being and quality of life were assessed using validated questionnaires...
February 16, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29452777/yoga-for-menopausal-symptoms-a-systematic-review-and-meta-analysis
#13
REVIEW
Holger Cramer, Wenbo Peng, Romy Lauche
OBJECTIVES: To systematically review and meta-analyze the effectiveness of yoga for menopausal symptoms. METHODS: Medline (via PubMed), the Cochrane Central Register of Controlled Trials, and Scopus were screened through to February 21, 2017 for randomized controlled trials (RCTs) comparing the effects of yoga on menopausal symptoms to those of no treatment or active comparators. Standardized mean differences (SMD) and 95% confidence intervals (CI) were calculated...
March 2018: Maturitas
https://www.readbyqxmd.com/read/29452590/factors-associated-with-persistent-posttraumatic-stress-disorder-among-u-s-military-service-members-and-veterans
#14
Richard F Armenta, Toni Rush, Cynthia A LeardMann, Jeffrey Millegan, Adam Cooper, Charles W Hoge
BACKGROUND: Posttraumatic stress disorder (PTSD) can have long-term and far-reaching impacts on health and social and occupational functioning. This study examined factors associated with persistent PTSD among U.S. service members and veterans. METHODS: Using baseline and follow-up (2001-2013) questionnaire data collected approximately every 3 years from the Millennium Cohort Study, multivariable logistic regression was conducted to determine factors associated with persistent PTSD...
February 17, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29450627/can-the-use-of-a-single-integrated-unitary-autonomic-index-provide-early-clues-for-eventual-eligibility-for-olympic-games
#15
Daniela Lucini, Roberto Sala, Antonio Spataro, Mara Malacarne, Manuela Benzi, Stefano Tamorri, Massimo Pagani
PURPOSE: Optimal autonomic regulation and stress resilience might be considered critical elements of athletic performance. We hypothesize that a novel unitary autonomic index for sports (ANSIs), together with a somatic stress related symptom score (4SQ) might help characterize athletes who were eventually selected for the Rio 2016 Olympic Games Italian team (Rio +). METHODS: In this retrospective study we examined 778 athletes (age 24.4 ± 6.7 yrs) who underwent a planned yearly pre-participation screening...
February 15, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29449869/off-label-prescription-of-psychiatric-drugs-by-non-psychiatrist-physicians-in-three-general-hospitals-in-germany
#16
Caroline Lücke, Jürgen M Gschossmann, Teja W Grömer, Sebastian Moeller, Charlotte E Schneider, Aikaterini Zikidi, Alexandra Philipsen, Helge H O Müller
Background: Off-label prescribing of psychoactive drugs is a common practice in psychiatry. Here, we sought to investigate the frequency of off-label prescribing in a population of hospitalized patients with a somatic illness who were also suffering from a psychiatric pathology. Methods: Using a prospective, observational design, we collected data from 982 hospitalized patients with a somatic illness for whom a psychiatric consultation was requested because of the presence of additional psychiatric symptoms...
2018: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29449820/headache-and-alexithymia-in-children-and-adolescents-what-is-the-connection
#17
REVIEW
Giulia Natalucci, Noemi Faedda, Dario Calderoni, Rita Cerutti, Paola Verdecchia, Vincenzo Guidetti
Background: Headache is one of the most common complaints in children and adolescents and comorbidity rates are very high and the major associated diseases are depression, anxiety, atopic disorders, sleep, and behavioral disorders. In recent years, it has been highlighted that difficulties regulating emotions such as alexithymia have also been associated with diagnosis of somatization. Methods: We carried out a mini review analyzing the relation between alexithymia and primary headache (e.g., migraine and tension type headache) in children and adolescents by synthesizing the relevant studies in the literature on PubMed, PsycINFO, and Google Scholar...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29448281/-evaluation-of-factor-structure-and-construct-validity-of-the-12-item-short-version-of-the-opd-structure-questionnaire-opd-sqs-in-psychosomatic-patients
#18
Alexander Obbarius, Nina Obbarius, Felix Fischer, Gregor Liegl, Matthias Rose
BACKGROUND: Screening for personality dysfunction is regarded as increasingly important for treatment planning in clinical settings as this allows to determine specific clinical pathways in an early stage. Recently, the 12-item OPD Structure Questionnaire (OPD-SQS) was developed for this purpose and initial results of the factor structure and validity have been published. This study aimed to investigate and validate the OPD-SQS in further patient samples beyond the team of developers and to provide reference values...
February 15, 2018: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/29446050/coping-mechanisms-for-psychosomatic-symptoms-among-aging-roman-catholic-german-priests
#19
Carlos I Man-Ging, Eckhard Frick, Klaus Baumann
To identify and investigate coping mechanisms and other factors which may impact upon the psychosomatic symptoms of aging German Roman Catholic priests. A cross-sectional study was conducted among 499 aging German Roman Catholic priests with standardized questionnaires: Brief Symptom Inventory, Coping Inventory Stressful Situations, and Religious Coping Scale. Task-Oriented Coping exhibited a significant difference between the two groups. Multiple regression analyses indicated that psychosomatic symptoms could be best predicted by means of Task-Oriented Coping mechanisms, identification with priesthood, and by a low Negative Religious Coping...
February 14, 2018: Journal of Religion and Health
https://www.readbyqxmd.com/read/29445280/the-differences-between-patients-with-panic-disorder-and-healthy-controls-in-psychophysiological-stress-profile
#20
Antonia Kotianova, Michal Kotian, Milos Slepecky, Michaela Chupacova, Jan Prasko, Ingrid Tonhajzerova
Background: Alarming somatic symptoms, in particular, cardiovascular symptoms, are the characteristic feature of panic attacks. Increased cardiac mortality and morbidity have been found in these patients. Power spectral analysis of electrocardiogram R-R intervals is known to be a particularly successful tool in the detection of autonomic instabilities in various clinical disorders. Our study aimed to compare patients with panic disorder and healthy controls in heart rate variation (HRV) parameters (very-low-frequency [VLF], low-frequency [LF], and high-frequency [HF] band components of R-R interval) in baseline and during the response to the mental task...
2018: Neuropsychiatric Disease and Treatment
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