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https://www.readbyqxmd.com/read/28820863/improvements-in-resilience-stress-and-somatic-symptoms-following-online-resilience-training-a-dose-response-effect
#1
Brad Smith, Andrew Shatté, Adam Perlman, Michael Siers, Wendy D Lynch
OBJECTIVE: To determine if participation in an online resilience program impacts resilience, stress, and somatic symptoms. METHODS: Approximately 600 enrollees in the meQuilibrium resilience program received a series of brief, individually prescribed video, and text training modules in a user-friendly format. Regression models tested how time in the program affected change in resilience from baseline and how changes in resilience affected change in stress and reported symptoms...
August 17, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28819132/treatment-associated-changes-of-functional-connectivity-of-midbrain-brainstem-nuclei-in-major-depressive-disorder
#2
Gerd Wagner, Feliberto de la Cruz, Stefanie Köhler, Karl-Jürgen Bär
Previous functional magnetic resonance imaging (fMRI) studies demonstrated an abnormally coordinated network functioning in Major Depression Disorder (MDD) during rest. The main monoamine-producing nuclei within midbrain/brainstem are functionally integrated within these specific networks. Therefore, we aimed to investigate the resting-state functional connectivity (RSFC) of these nuclei in 45 MDD patients and differences between patients receiving two different classes of antidepressant drugs. Patients showed reduced RSFC from the ventral tegmental area (VTA) to dorsal anterior cingulate cortex (dACC) and stronger RSFC to the left amygdala and dorsolateral prefrontal cortex (DLPFC)...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28814899/irritable-bowel-symptoms-and-the-development-of-common-mental-disorders-and-functional-somatic-syndromes-identified-in-secondary-care-a-long-term-population-based-study
#3
Chalotte Heinsvig Poulsen, Lene Falgaard Eplov, Carsten Hjorthøj, Marie Eliasen, Sine Skovbjerg, Thomas Meinertz Dantoft, Andreas Schröder, Torben Jørgensen
OBJECTIVE: Irritable bowel syndrome (IBS) is associated with mental vulnerability, and half of patients report comorbid somatic and mental symptoms. We aimed to investigate the relationship between an IBS symptom continuum and the subsequent development of common mental disorders (CMDs) and functional somatic syndromes (FSSs). METHODS AND STUDY DESIGN: A longitudinal population-based study comprising two 5-year follow-up studies, Dan-MONICA 1 (1982-1987) and Inter99 (1999-2004), recruited from the western part of Copenhagen County...
2017: Clinical Epidemiology
https://www.readbyqxmd.com/read/28811068/a-positron-emission-tomography-study-of-the-serotonergic-system-in-relation-to-anxiety-in-depression
#4
Zafer Iscan, Gopalkumar Rakesh, Samantha Rossano, Jie Yang, Mengru Zhang, Jeffrey Miller, Gregory M Sullivan, Priya Sharma, Matthew McClure, Maria A Oquendo, J John Mann, Ramin V Parsey, Christine DeLorenzo
Symptoms of anxiety are highly comorbid with major depressive disorder (MDD) and are known to alter the course of the disease. To help elucidate the biological underpinnings of these prevalent disorders, we previously examined the relationship between components of anxiety (somatic, psychic and motoric) and serotonin 1A receptor (5-HT1A) binding in MDD and found that higher psychic and lower somatic anxiety was associated with greater 5-HT1A binding. In this work, we sought to examine the correlation between these anxiety symptom dimensions and 5-HTT binding...
August 12, 2017: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28810445/enduring-somatic-threat-perceptions-and-post-traumatic-stress-disorder-symptoms-in-survivors-of-cardiac-events
#5
Laura Meli, Carmela Alcántara, Jennifer A Sumner, Brendan Swan, Bernard P Chang, Donald Edmondson
Post-traumatic stress disorder due to acute cardiovascular events may be uniquely defined by enduring perceptions of somatic threat. We tested whether post-traumatic stress disorder at 1 month post-acute coronary syndrome indeed required both high peritraumatic threat during the acute coronary syndrome and ongoing cardiac threat perceptions. We assessed peritraumatic threat during emergency department enrollment of 284 patients with a provisional acute coronary syndrome diagnosis and cardiac threat perceptions and post-traumatic stress disorder symptoms 1 month post-discharge...
April 1, 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28808897/should-posttraumatic-stress-be-a-disorder-or-a-specifier-towards-improved-nosology-within-the-dsm-categorical-classification-system
#6
REVIEW
Jeffrey Guina, Matthew Baker, Kelly Stinson, Jon Maust, Joseph Coles, Pamela Broderick
PURPOSE OF REVIEW: Since 1980, posttraumatic stress (PTS) disorder has been controversial because of its origin as a social construct, its discriminating trauma definition, and the Procrustean array of symptoms/clusters chosen for inclusion/exclusion. This review summarizes the history of trauma-related nosology and proposed changes, within current categorical models (trauma definitions, symptoms/clusters, subtypes/specifiers, disorders) and new models. RECENT FINDINGS: Considering that trauma is a risk factor for virtually all mental disorders (particularly depressive, anxiety, dissociative, personality), the multi-finality of trauma (some survivors are resilient, and some develop PTS and/or non-PTS symptoms), and the various symptoms that trauma survivors express (mood, cognitive, perceptual, somatic), it is difficult to classify PTS...
August 15, 2017: Current Psychiatry Reports
https://www.readbyqxmd.com/read/28808371/efficacy-of-osteopathic-manipulative-treatment-approach-in-the-patient-with-pulmonary-fibrosis-in-critical-care-outpatient-department
#7
Manu Goyal, Kanu Goyal, Kanimozhi Narkeesh, Asir John Samuel, Narkeesh Arumugam, Subhasish Chatterjee, Sorabh Sharma
The purpose of the present case study was to explore the efficacy of osteopathic manipulative treatment (OMT) in patient with pulmonary fibrosis (PF) in the critical care outpatient department. Here, we present a 48-year-old male case with breathlessness, increased frequency of defecation, and pain in and around the nape of neck with diagnosed pulmonary fibrosis. He scored 3 on a patient-reported modified Medical Research Council (mMRC) dyspnea scale. Osteopathic examination reveals multiple somatic findings across the chest and abdominal region and treated by OMT...
July 2017: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/28807062/neuropsychiatric-characteristics-of-antiterrorist-operation-combatants-in-the-donbass-ukraine
#8
Konstantin N Loganovsky, Natalia A Zdanevich, Marina V Gresko, Donatella Marazziti, Tatiana K Loganovskaja
OBJECTIVE: The present paper aimed to explore the neuropsychiatric characteristics of the antiterrorism (ATO) combatants in the Donets Basin (Donbass) and to propose therapeutic strategies for managing their mental healthcare. METHODS: A total of 54 ATO combatants were included in our study and compared with four groups of subjects exposed to other emergencies, including the Chernobyl disaster and the war in Afghanistan. The neuropsychiatric features were assessed through psychopathological assessments, neurological examinations, and quantitative electroencephalography (qEEG)...
August 15, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/28806206/chronic-pain-and-associated-factors-in-india-and-nepal-a-pilot-study-of-the-vanderbilt-global-pain-survey
#9
Jenna L Walters, Kelly Baxter, Hannah Chapman, Tracy Jackson, Adinarayanan Sethuramachandran, Marcus Couldridge, Hem Raj Joshi, Pankaj Kundra, Xulei Liu, Divya Nair, Bonnie Sullivan, Matthew S Shotwell, Ryan J Jense, Nicholas J Kassebaum, K A Kelly McQueen
BACKGROUND: Evaluation and treatment of chronic pain worldwide are limited by the lack of standardized assessment tools incorporating consistent definitions of pain chronicity and specific queries of known social and psychological risk factors for chronic pain. The Vanderbilt Global Pain Survey (VGPS) was developed as a tool to address these concerns, specifically in the low- and middle-income countries where global burden is highest. METHODS: The VGPS was developed using standardized and cross-culturally validated metrics, including the Brief Pain Inventory and World Health Organization Disability Assessment Scale, as well as the Pain Catastrophizing Scale, the Fibromyalgia Survey Questionnaire along with queries about pain attitudes to assess the prevalence of chronic pain and disability along with its psychosocial and emotional associations...
August 10, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28803349/scary-symptoms-functional-magnetic-resonance-imaging-evidence-for-symptom-interpretation-bias-in-pathological-health-anxiety
#10
Zhimin Yan, Michael Witthöft, Josef Bailer, Carsten Diener, Daniela Mier
Patients with pathological health anxiety (PHA) tend to automatically interpret bodily sensations as sign of a severe illness. To elucidate the neural correlates of this cognitive bias, we applied an functional magnetic resonance imaging adaption of a body-symptom implicit association test with symptom words in patients with PHA (n = 32) in comparison to patients with depression (n = 29) and healthy participants (n = 35). On the behavioral level, patients with PHA did not significantly differ from the control groups...
August 12, 2017: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/28802935/depression-and-anxiety-in-parkinson-s-disease
#11
Anette Schrag, Raquel N Taddei
Depression and anxiety are some of the most common comorbidities arising in patients with Parkinson's disease. However, their timely recognition and diagnosis are often hindered by overlap with other somatic features and a low rate of self-report. There is a need for greater awareness and for better assessment and treatment options are highly required. Currently available scales can serve as tools to monitor change over time and the effect of interventional strategies. Development of new therapeutic strategies, including nonpharmacological approaches such as transcranial magnetic stimulation and deep brain stimulation, may provide alternatives to currently available treatment approaches...
2017: International Review of Neurobiology
https://www.readbyqxmd.com/read/28801385/diagnostic-barriers-for-somatic-symptom-disorders-in-primary-care-study-protocol-for-a-mixed-methods-study-in-germany
#12
Christina Heinbokel, Marco Lehmann, Nadine Janis Pohontsch, Thomas Zimmermann, Astrid Althaus, Martin Scherer, Bernd Löwe
INTRODUCTION: Somatoform or somatic symptom disorders ((S)SD) are common and have a negative impact on the patients' health-related quality of life, healthcare use and costs. In primary care, which is central to the management of (S)SD, diagnosis and treatment tend to be delayed. There is a significant lack of evidence regarding the barriers in the diagnostic process of (S)SD in primary care and how interventions should be tailored to address them. The aim of this study is to analyse the diagnostic process in primary care that results in the diagnosis or non-diagnosis of a (S)SD...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28799704/the-nature-consequences-and-management-of-neurological-disorders-in-chronic-kidney-disease
#13
REVIEW
Bahman Jabbari, Nosratola D Vaziri
Perhaps no other organ in the body is affected as often and in as many ways as the brain is in patients with chronic kidney disease (CKD). Several factors contribute to the neurological disorders in CKD including accumulation of uremic toxins, metabolic and hemodynamic disorders, oxidative stress, inflammation, and impaired blood brain barrier among others. The neurological disorders in CKD involve both peripheral and central nervous system. The peripheral neurological symptoms of CKD are due to somatic and cranial peripheral neuropathies as well as a myopathy...
August 11, 2017: Hemodialysis International
https://www.readbyqxmd.com/read/28794982/symptom-correlates-of-cerebral-blood-flow-following-acute-concussion
#14
Nathan W Churchill, Michael G Hutchison, Simon J Graham, Tom A Schweizer
Concussion is associated with significant symptoms within hours to days post-injury, including disturbances in physical function, cognition, sleep and emotion. However, little is known about how subjective impairments correlate with objective measures of cerebrovascular function following brain injury. This study examined the relationship between symptoms and cerebral blood flow (CBF) in individuals following sport-related concussion. Seventy university level athletes had CBF measured using Arterial Spin Labelling (ASL), including 35 with acute concussion and 35 matched controls and their symptoms were assessed using the Sport Concussion Assessment Tool 3 (SCAT3)...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28792287/the-association-of-generalized-anxiety-disorder-and-somatic-symptoms-with-frequent-attendance-to-health-care-services-a-cross-sectional-study-from-the-northern-finland-birth-cohort-1966
#15
Tero S Kujanpää, Jari Jokelainen, Juha P Auvinen, Markku J Timonen
Objective Generalized anxiety disorder is associated with higher rate of physical comorbities, unexplained symptoms, and health care utilization. However, the role of somatic symptoms in determining health care utilization is unclear. The present study aims to assess the association of frequent attendance of health care services between generalized anxiety disorder symptoms and somatic symptoms. Method This study was conducted cross-sectionally using the material of the 46-year follow-up survey of the Northern Finland Birth Cohort 1966...
March 2017: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/28791690/apathy-risk-factor-for-mortality-in-nursing-home-patients
#16
Johanna M H Nijsten, Ruslan Leontjevas, Ron Pat-El, Martin Smalbrugge, Raymond T C M Koopmans, Debby L Gerritsen
OBJECTIVES: To determine the prognostic value of apathy for mortality in patients of somatic (SC) and dementia special care (DSC) nursing home (NH) units. DESIGN: Longitudinal design, secondary analyses of a 2-year, cluster-randomized trial with six measurements, approximately 4 months in between. SETTING: SC and DSC-units of Dutch NHs. PARTICIPANTS: NH-patients of seventeen SC-units (n = 342) and sixteen DCS-units (n = 371)...
August 9, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28781213/quality-of-life-and-sexual-function-benefits-of-long-term-testosterone-treatment-longitudinal-results-from-the-registry-of-hypogonadism-in-men-rhyme
#17
Raymond C Rosen, Frederick Wu, Hermann M Behre, Hartmut Porst, Eric J H Meuleman, Mario Maggi, Javier Romero-Otero, Juan I Martinez-Salamanca, Thomas Hugh Jones, Frans M J Debruyne, Karl-Heinz Kurth, Geoff I Hackett, Richard Quinton, Peter Stroberg, Yacov Reisman, Edoardo S Pescatori, Antonio Morales, Lluis Bassas, Natalio Cruz, Glenn R Cunningham, Olivia A Wheaton
BACKGROUND: The benefits and risks of long-term testosterone administration have been a topic of much scientific and regulatory interest in recent years. AIM: To assess long-term quality of life (QOL) and sexual function benefits of testosterone replacement therapy (TRT) prospectively in a diverse, multinational cohort of men with hypogonadism. METHODS: A multinational patient registry was used to assess long-term changes associated with TRT in middle-age and older men with hypogonadism...
August 3, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28780925/motivational-mechanisms-in-the-relation-between-job-characteristics-and-employee-functioning
#18
Anja H Olafsen, Hallgeir Halvari
This study investigates the job demands-resources (JD-R) model in relation to work motivation in a self-determination theory (SDT) perspective, with the purpose of developing a model where social-contextual factors are seen in relation to psychological needs in order to explain autonomous work motivation and, in turn, self-reported work performance and somatic symptom burden. SEM-analyses of cross-sectional survey data including 405 waiters/waitresses in Norway were conducted to evaluate the hypothesized model...
August 7, 2017: Spanish Journal of Psychology
https://www.readbyqxmd.com/read/28780904/the-impact-of-age-bmi-and-sex-hormone-on-aging-males-symptoms-and-the-international-index-of-erectile-function-scores
#19
Xiao-Hua Yu, Jing Zhao, Shu-Cheng Zhang, Jian-Hui Li, Jun-Biao Zheng, Zheng Li, Guo-Qing Liang, Hui-Juan Shi, Wei-Jin Zhou, Qian-Xi Zhu
OBJECTIVE: To analyze the impact of age, BMI and sex hormone on aging males' symptoms (AMS) and the 5-item version of the international index of erectile function (IIEF-5) scores in middle-aged and elderly Chinese men. METHODS: A population-based cross-sectional study was conducted in Jiashan County. A total of 969 men, aged between 40 and 80 years old, were admitted. Physical examination and the sex hormones were measured, and AMS and IIEF-5 scores were assessed...
August 5, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28769589/exploring-symptoms-of-somatization-in-chronic-widespread-pain-latent-class-analysis-and-the-role-of-personality
#20
Andrea Burri, Peter Hilpert, Peter McNair, Frances M Williams
Chronic widespread musculoskeletal pain (CWP) is a condition manifesting varied co-symptomatology and considerable heterogeneity in symptom profiles. This poses an obstacle for disease definition and effective treatment. Latent class analysis (LCA) provides an opportunity to find subtypes of cases in multivariate data. In this study, LCA was used to investigate whether and how individuals with CWP could be classified according to 12 additional somatic symptoms (migraine headaches, insomnia, stiffness, etc.)...
2017: Journal of Pain Research
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