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https://www.readbyqxmd.com/read/28728805/associations-of-c-reactive-protein-and-psychological-distress-are-modified-by-antidepressants-supporting-an-inflammatory-depression-subtype-findings-from-ukhls
#1
Authors Amanda Hughes, Meena Kumari
BACKGROUND: Clinical evidence increasingly suggests inflammation may be important specifically for an etiologically distinct depression subtype, characterized by resistance to antidepressant medication. However, epidemiological investigations of the relationship of inflammation with depression and psychological distress have failed to acknowledge these developments, which may have resulted in bias or masking of associations driven by the subtype. This may have contributed to inconsistent results in epidemiological studies, and equivocal support for an inflammation-depression link...
July 17, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28726467/the-importance-of-the-neighborhood-in-the-2014-ebola-outbreak-in-the-united-states-distress-worry-and-functioning
#2
Rupa Jose, E Alison Holman, Roxane Cohen Silver
OBJECTIVE: Ebola media coverage directed public attention to potential disease carriers: residents or travelers from West Africa. We investigated the role of neighborhood population factors (i.e., the concentration of West African foreigners, non-West African foreigners, non-Hispanic Blacks) on individual responses to the Ebola outbreak in the United States. The role of these community-level factors in emotional responses to this public health crisis is poorly understood. METHOD: Demographic factors, mental health, and stressful event history, collected as part of an ongoing longitudinal study of residents from 2 metropolitan communities (New York City and Boston, total N = 1,346), were combined with neighborhood data from the U...
July 20, 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/28725969/mastocytosis-from-a-molecular-point-of-view
#3
REVIEW
Daniel Elieh Ali Komi, Todd Rambasek, Stefan Wöhrl
Mast cells (MCs) are physiologically activated by binding of stem cell factor (SCF) to the extracellular domains of the Kit receptor. This binding increases the proliferation and prolongs the survival of normal mature MCs, as well as intensifies the release of mediators. In mastocytosis, somatic mutations of the coding Kit gene cause autocrine dysregulation and lead to constitutive KIT activation even in the absence of its ligand SCF. Clinical symptoms are caused by MC-mediator release and/or infiltration of MCs into tissues...
July 19, 2017: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/28719808/activated-neuro-oxidative-and-neuro-nitrosative-pathways-at-the-end-of-term-are-associated-with-inflammation-and-physio-somatic-and-depression-symptoms-while-predicting-outcome-characteristics-in-mother-and-baby
#4
Chutima Roomruangwong, Decio Sabbatini Barbosa, Andressa Keiko Matsumoto, André de Souza Nogueira, Buranee Kanchanatawan, Sunee Sirivichayakul, André F Carvalho, Sebastien Duleu, Michel Geffard, Estefania Gastaldello Moreira, Michael Maes
OBJECTIVES: To examine oxidative & nitrosative stress (O&NS) biomarkers at the end of term in relation to perinatal affective symptoms, neuro-immune biomarkers and pregnancy-related outcome variables. METHODS: We measured plasma advanced oxidation protein products (AOPP), nitric oxide metabolites (NOx), total radical trapping antioxidant parameter (TRAP), -sulfhydryl (-SH), peroxides (LOOH) and paraoxonase (PON)1 activity in pregnant women with and without prenatal depression and non-pregnant controls...
July 6, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28718346/effect-of-desvenlafaxine-50-mg-and-100-mg-on-energy-and-lassitude-in-patients-with-major-depressive-disorder-a-pooled-analysis
#5
Raymond W Lam, Dalia B Wajsbrot, Ellen Meier, Elizabeth Pappadopulos, Joan A Mackell, Matthieu Boucher
Nine randomized, double-blind, placebo-controlled studies of major depressive disorder were pooled to evaluate the effects of desvenlafaxine 50- and 100-mg/d on energy and lassitude in adults with major depressive disorder ( n=4279). Changes from baseline to endpoint in 17-item Hamilton Rating Scale for Depression (HAM-D17) Work and Activities, Retardation, and Somatic Symptoms General items, HAM-D17 psychomotor retardation factor, and Montgomery-Åsberg Depression Rating Scale Lassitude item were analyzed with a mixed model for repeated measures analysis of variance...
July 1, 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/28713089/-peculiarities-of-clinical-psychopathological-phenomenology-of-chronic-neuropathies
#6
Olexandr O Belov, Tetiana P Rysynets, Elena F Shkondina, Iryna S Pototska
INTRODUCTION: The study of psycho-emotional reactions associated with chronic neuropathies, is an important factor of the integrated solution to the problem of treatment and prevention of disorders of the peripheral nervous system. The aim of the research is to study clinical psychopathological phenomenology and personality characteristics of patients suffering from chronic neuropathies. MATERIAL AND METHODS: We examined 115 patients with chronic neuropathies in comparison with 60 healthy persons using a clinical conversation method, shortened multivariable personality questionnaire, The Zung Self-Rating Depression Scale, Spilberger's scale of trait and state anxiety and Symptom Check List-90-Revised questionnaire...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28713080/clinical-and-psychopathological-characteristics-of-the-autoagressive-behavior-in-patients-with-the-first-psychotic-episode-with-considering-circadian-rhythms
#7
Dmytro I Boiko, Lilia V Zhyvotovska, Grigorij T Sonnik, Andrij M Skrypnіkov
INTRODUCTION: The high rate of autoagressive action in patients with psychotic symptoms manifested during the beginning of active psychopharmatherapy, and they are often the reason for psychiatric help. The continuous growth of autoagressive behavior indicates the number of unsolved problems in clinical suicidology. AIM: The aim of this research was to explore the clinical and psychopathological characteristics of the autoagressive behavior in patients with the first psychotic episode with considering circadian rhythms...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28712419/the-relationship-between-childhood-adversities-and-fibromyalgia-in-the-general-population
#8
Aleksi Varinen, Elise Kosunen, Kari Mattila, Tuomas Koskela, Markku Sumanen
BACKGROUND: Fibromyalgia is a syndrome characterized by widespread pain and a variety of somatic symptoms. The international prevalence of fibromyalgia is 2-5%, but its current prevalence in Finland is unclear. Various adversities are linked to the onset of fibromyalgia. However, there is need for more data regarding the association between childhood physical abuse and fibromyalgia. Further, the association of childhood emotional stressors and fibromyalgia is disputed. The aim of the current study is to produce more information about that relationship using data from the Health and Social Support (HeSSup) Study...
August 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28710565/somatic-symptom-severity-among-primary-care-patients-who-are-obese-examining-the-unique-contributions-of-anxiety-sensitivity-discomfort-intolerance-and-health-anxiety
#9
Thomas A Fergus, Christine A Limbers, Jackson O Griggs, Lance P Kelley
Prior research indicates the common presentation of somatic symptoms and obesity in primary care settings, as well as links between obesity and somatic symptoms. Anxiety sensitivity, discomfort intolerance, and health anxiety are three variables relevant to somatic symptoms. How those three variables relate to somatic symptom severity among individuals who are obese and the unique variance accounted for by each variable in somatic symptom severity remains unexamined. Among a large sample of primary care patients who are obese (N = 342), anxiety sensitivity, discomfort intolerance, and health anxiety collectively accounted for 35% of variance in somatic symptom severity beyond the effects of sociodemographic variables, body mass index, medical morbidity, and depression severity...
July 14, 2017: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28709689/psychiatric-reactions-to-continuous-traumatic-stress-a-latent-profile-analysis-of-two-israeli-samples
#10
Liat Itzhaky, Mark Gelkopf, Yafit Levin, Jacob Y Stein, Zahava Solomon
Many individuals worldwide are exposed to continuous traumatic stress (CTS). However, the psychiatric sequela of CTS and the relevance of posttraumatic stress disorder (PTSD) diagnostic criteria in this situation have yet to be determined. Filling this gap, the present study assessed psychiatric reactions to CTS and the relationship between such reactions and functional impairment among two representative samples of adults exposed to ongoing shelling over 6 (n=387) and 9 years (n=468). Assessment included PTSD symptomatology (i...
June 29, 2017: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/28707502/appraisal-of-the-psychiatric-diagnostic-screening-questionnaire-in-a-perinatal-cohort-the-apron-study
#11
Brenda Leung, Nicole Letourneau, Katherine Bright, Gerald F Giesbrecht, Henry Ntanda, Lisa Gagnon
BACKGROUND: Depression and anxiety are routinely screened as part of perinatal care. However, other Axis 1 disorders and specific anxiety disorders are less likely to be screened or assessed as part of obstetric care. The objective of this study was to determine whether the Psychiatric Diagnostic Screening Questionnaire (PDSQ) is a potentially useful tool to screen for psychiatric conditions in pregnant and postpartum women in a community setting. METHODS: We compared the prevalence of DSM Axis I disorders obtained on the PDSQ with: (1) the prevalence of these disorders reported in previous studies of pregnant and postpartum women, and (2) scores obtained on the Edinburgh Postpartum Depression Scale (EPDS) and the Symptom Checklist-90-Revised (SCL-90R) anxiety scale...
July 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/28707491/the-effect-of-omega-3-fatty-acid-supplementation-on-premenstrual-syndrome-and-health-related-quality-of-life-a-randomized-clinical-trial
#12
Samira Behboudi-Gandevani, Fatemeh-Zahra Hariri, Lida Moghaddam-Banaem
INTRODUCTION: Most reproductive aged women suffer from somatic and mental disorders prior to menstruation. This study investigated whether omega-3 supplement improved premenstrual symptoms and health-related quality of life among reproductive aged women. METHODS: A multi-center, balanced (1:1), placebo-controlled, parallel-group randomized clinical trial was conducted in an urban academic institution. A sample consisting of 95 Iranian women aged 20-35 years who were suffering from premenstrual symptoms were randomly allocated into two groups...
July 14, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28706562/psychological-health-and-religious-coping-of-ghanaian-women-with-infertility
#13
Mabel Oti-Boadi, Kwaku Oppong Asante
BACKGROUND: Infertility has been shown to have considerable psychological effects on the well-being of couples, especially women. Religion has been found as a resource used by infertile women to cope with their distress. Little research has examined the influence of religious coping on psychological distress among infertile women in Ghana. This study examines the relationship between positive and negative religious coping and psychological health for women with infertility problems in Ghana...
2017: BioPsychoSocial Medicine
https://www.readbyqxmd.com/read/28706503/parental-post-traumatic-stress-disorder-symptoms-are-related-to-successful-aging-in-offspring-of-holocaust-survivors
#14
Amit Shrira, Liat Ayalon, Moshe Bensimon, Ehud Bodner, Tova Rosenbloom, Gal Yadid
A fascinating, yet underexplored, question is whether traumatic events experienced by previous generations affect the aging process of subsequent generations. This question is especially relevant for offspring of Holocaust survivors (OHS), who begin to face the aging process. Some preliminary findings point to greater physical dysfunction among middle-aged OHS, yet the mechanisms behind this dysfunction need further clarification. Therefore, the current studies assess aging OHS using the broad-scoped conceptualization of successful aging, while examining whether offspring successful aging relates to parental post-traumatic stress disorder (PTSD) symptoms and offspring's secondary traumatization symptoms...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28705297/the-diagnosis-and-treatment-of-behavioral-disorders-in-dementia
#15
Torsten Kratz
BACKGROUND: Behavioral disorders such as aggressiveness, agitation, delusions, disinhibition, affect lability, and apathy arise in more than 90% of patients with dementia. Behavioral disorders are a major challenge and the greatest stress factor in everyday life for nursing personnel and for family members caring for the patient. METHODS: This review is based on relevant publications retrieved by a selective literature search in the PubMed, Cochrane Library, and German S3 guideline databases with the search terms "behavioral disorders," "non-cognitive disorders," and "challenging behavior," in conjunction with "dementia" and "behavioral and psychological symptoms of dementia...
June 30, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/28705210/transcutaneous-electrical-stimulation-of-somatic-afferent-nerves-in-the-foot-relieved-symptoms-related-to-postoperative-bladder-spasms
#16
Chanjuan Zhang, Zhiying Xiao, Xiulin Zhang, Liqiang Guo, Wendong Sun, Changfeng Tai, Zhaoqun Jiang, Yuqiang Liu
BACKGROUND: Bladder spasm is a common side effect of urological surgery. Main treatment modalities include opioids or anticholinergic medication; however, bladder spasms still occur even after these interventions. Recent studies indicate that transcutaneous stimulation of the foot can result in 50% increase in bladder capacity in healthy adults, and inhibit bladder detrusor overactivity in spinal cord injured patients. In this study, we examined the effects of transcutaneous electrical stimulation of the foot on bladder spasms related symptoms...
July 13, 2017: BMC Urology
https://www.readbyqxmd.com/read/28702757/mental-distress-factors-and-exercise-capacity-in-patients-with-coronary-artery-disease-attending-cardiac-rehabilitation-program
#17
Nijole Kazukauskiene, Julius Burkauskas, Jurate Macijauskiene, Inga Duoneliene, Vaidute Gelziniene, Vilija Jakumaite, Julija Brozaitiene
PURPOSE: There is still insufficient data on mental distress factors contributing to exercise capacity (EC) improvement before and after cardiac rehabilitation (CR) in patients with coronary artery disease (CAD). The aim of our study was to evaluate the associations between various mental distress factors and EC before and after exercise-based CR (EBCR). METHODS: Over 12 months, 223 CAD patients (70% men, mean age 58 ± 9 years) were evaluated for socio-demographic, clinical, and mental distress symptoms as measured by the Hospital Anxiety and Depression scale (HADS), Beck Depression Inventory-II (BDI-II), and Spielberger State-Trait Anxiety Inventory (STAI)...
July 12, 2017: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28700701/development-and-validation-of-the-maugeri-sleep-quality-and-distress-inventory-masqudi-17
#18
Elisa Morrone, Cinzia Sguazzin, Giorgio Bertolotti, Andrea Giordano, Alberto Braghiroli, Gian Luigi Balestroni, Raffaele Manni, Luigi Ferini Strambi, Vincenza Castronovo, Marco Zucconi, Fabrizio De Carli, Eleonora Pinna, Marcella Ottonello, Ines Giorgi, Michele Terzaghi, Sara Marelli, Francesco Fanfulla
OBJECTIVES: The aim of this study was to develop and validate a questionnaire designed to measure the impact of sleep impairment on emotional distress in patients with various sleep disorders. METHODS: Five experts created an item data-bank pertaining to sleep-related psychological symptoms and somatic perceptions. Fifty patients in two focus groups examined each item for: a) word clarity (indicating any ambiguity of interpretation) and b) appropriateness for the target population...
2017: PloS One
https://www.readbyqxmd.com/read/28696624/-it-all-started-with-a-simple-symptom-and-then%C3%A2-basic-palliative-medical-tools-for-primary-care-physicians
#19
Christophe Dulong De Rosnay, Tony Tai, Olivier Pasche
The treatment of symptoms in palliative care is of primary importance, though this in itself is not sufficient for the relief of all aspects of a patient's suffering. Pain, dyspnea, or anxiety cannot be reduced to a single somatic characteristic, the psychological implications and the consequences on the patient's daily life being of paramount importance. A respect with regard to certain basic principles, and a full knowledge of the main therapeutic approaches available, allow for a better initial management of the symptoms...
November 2, 2016: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28695806/illness-attribution-of-outpatients-with-multiple-somatic-symptoms-in-peking-union-medical-college-hospital
#20
Tao Li, Xia Hong, Nana Xiong, Jing Jiang, Xiayuan Sun, Liming Zhu, Guoqing Tian, Jing Wei
Objective To explore the characteristics of illness attribution of outpatients with multiple somatic symptoms in Peking Union Medical College Hospital. Methods It was a cross-sectional study conducted from March to October,2012. A total of 150 outpatients were recruited from the departments of Gastroenterology,Traditional Chinese Medicine and Psychological Medicine by convenience sampling. Somatic symptom scale of the Patient Health Questionnaire (PHQ-15) was used to screening each patient in the waiting list...
June 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
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