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https://www.readbyqxmd.com/read/29933411/time-trends-in-dyspepsia-and-association-with-h-pylori-and-work-related-stress-an-observational-study-in-white-collar-employees-in-1996-and-2015
#1
Stefanie Braig, Simon Berger, David Rothenbacher, Stefanie Schmid, Thomas Seufferlein, Hermann Brenner, Dietrich Rothenbacher, Harald Gündel
PURPOSE: We aimed to describe time trends in functional dyspepsia and the association of dyspepsia-related factors, Helicobacter pylori (H. pylori) and work-related stress with functional dyspepsia in white collar employees in 1996 and 2015. MATERIALS AND METHODS: Repeat cross-sectional study conducted in 1996 (n = 190, response rate = 76.1) and 2015 (n = 195, response rate = 40.2) within a health insurance company in South-West Germany. Dyspeptic symptoms measured according to the Rome III criteria, effort-reward imbalance and further work- or dyspepsia-related factors were assessed by self-administered questionnaire...
2018: PloS One
https://www.readbyqxmd.com/read/29933282/concussion-symptom-profiles-among-child-adolescent-and-young-adult-athletes
#2
David R Howell, Peter Kriz, Rebekah C Mannix, Tyler Kirchberg, Christina L Master, William P Meehan
OBJECTIVES: (1) To examine how age influences initial symptom presentation following concussion; and (2) to determine whether specific symptom profiles are associated with duration of postconcussion symptoms, and whether they vary by age group. DESIGN: A total of 689 patients (20% children 7-12 years of age, 69% adolescents 13-18 years of age, and 11% young adults 19-30 years of age) were seen and diagnosed with a concussion within 21 days after injury. Patients completed the Post-Concussion Symptom Scale (PCSS) and were followed until they no longer required care...
June 21, 2018: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29928536/the-effect-of-workplace-bullying-perception-on-psychological-symptoms-a-structural-equation-approach
#3
Pınar Duru, Mine Esin Ocaktan, Ümit Çelen, Özlem Örsal
Background: The aims of this study were to determine the extent of workplace bullying perceptions among the employees of a Faculty of Medicine, evaluating the variables considered to be associated, and determining the effect of workplace bullying perceptions on their psychological symptoms evaluated by the Brief Symptom Inventory (BSI). Methods: This cross-sectional study was performed involving 355 (88.75%) employees. Results: Levels of perceived workplace bullying were found to increase with the increasing scores for BSI and BSI sub-dimensions of anxiety, depression, negative self, somatization, and hostility (all p  < 0...
June 2018: Safety and Health At Work
https://www.readbyqxmd.com/read/29927990/ptsd-correlates-with-somatization-in-sexually-abused-children-type-of-abuse-moderates-the-effect-of-ptsd-on-somatization
#4
Seung Min Bae, Jae Myeong Kang, Hyoung Yoon Chang, Woori Han, So Hee Lee
PURPOSE: Somatization is a major post-traumatic symptom in sexually abused children. Thus, the present study aimed to determine the relationship between post-traumatic stress disorder (PTSD) symptoms and somatization, and between intelligence and somatization in child sexual abuse victims and to elucidate whether type of abuse had an effect on the relationship between PTSD symptoms and somatization. METHODS: This study evaluated the somatizations (Child Behavioral Checklist/6-18 [CBCL]), PTSD symptoms (Trauma Symptom Checklist for Children [TSCC]), and intelligence levels of 63 sexually abused children...
2018: PloS One
https://www.readbyqxmd.com/read/29925460/the-symptomatology-of-psychological-trauma-in-the-aftermath-of-war-1945-1980-uk-army-veterans-civilians-and-emergency-responders
#5
Alberta Engelbrecht, Howard Burdett, Maria João Silva, Kamaldeep Bhui, Edgar Jones
BACKGROUND: UK veterans suffering from a psychological or psychiatric illness as a consequence of service in the Second World War were entitled to a war pension. Their case files, which include regular medical assessments, are a valuable resource to investigate the nature, distribution and duration of symptoms. METHODS: A standardised form was used to collect data from pension records of a random sample of 500 UK army veterans from the first presentation in the 1940s until 1980...
June 21, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29920958/ultrahigh-risk-for-developing-psychosis-and-psychotic-personality-organization
#6
Mark van der Gaag, Liesbeth Eurelings-Bontekoe, Helga Ising, David van den Berg
AIMS: Childhood adversities combined with unsafe parenting may disturb personality development. This study investigated whether psychotic personality organization as defined by Kernberg and assessed with de Dutch Short Form of the MMPI (DSFM) is more prevalent in ultrahigh risk (UHR) for psychosis compared with non-psychotic psychiatric control patients (NPPC). METHODS: A total of 73 UHR and 119 NPPC patients were assessed with the DSFM and the Comprehensive Assessment of at Risk Mental States (CAARMS)...
June 19, 2018: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29914406/management-of-patients-with-persistent-medically-unexplained-symptoms-a-descriptive-study
#7
Kate Sitnikova, Rinske Pret-Oskam, Sandra M A Dijkstra-Kersten, Stephanie S Leone, Harm W J van Marwijk, Henriëtte E van der Horst, Johannes C van der Wouden
BACKGROUND: In 2013 the Dutch guideline for management of medically unexplained symptoms (MUS) was published. The aim of this study is to assess medical care for patients with persistent MUS as recorded in their electronic medical records, to investigate if this is in line with the national guideline for persistent MUS and whether there are changes in care over time. METHODS: We conducted an observational study of adult primary care patients with MUS. Routinely recorded health care data were extracted from electronic medical records of patients participating in an ongoing randomised controlled trial in 30 general practices in the Netherlands...
June 18, 2018: BMC Family Practice
https://www.readbyqxmd.com/read/29914310/dietary-patterns-in-relation-with-psychosomatic-complaints-profile-results-from-sepahan-study-among-a-large-sample-of-general-adults
#8
Fahimeh Haghighatdoost, Awat Feizi, Ahmad Esmaeilzadeh, Ammar Hassanzadeh Keshteli, Hamidreza Roohafza, Hamid Afshar, Peyman Adibi
OBJECTIVE: Although dietary patterns have been evaluated in relation to psychological disorders, their associations with psychosomatic complaints are unclear. We investigated relations of dietary patterns with psychosomatic complaints profiles. METHODS: In this cross-sectional study, a total of 3363 adults were included. Dietary intakes and psychosomatic complaints were assessed using self-administered Persian validated questionnaires. Dietary patterns and psychosomatic symptom profiles were identified using exploratory factor analysis...
June 18, 2018: Nutritional Neuroscience
https://www.readbyqxmd.com/read/29913921/applying-dialectical-behavior-therapy-to-chronic-pain-a-case-study
#9
Steven J Linton
Background and aims Chronic pain patients often present with a host of psychological and somatic problems and are unable to work despite receiving traditional pain management. For example, it is common that patients with persistent pain also suffer from a variety of anxiety and depressive symptoms. Indeed, the regulation of emotions may be one important factor that is associated with the development of persistent pain. Dialectical behavior therapy, a form of cognitive-behavioral therapy, focuses on emotion regulation and has successfully addressed other complex problems...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29912465/prevalence-and-pattern-of-psychosocial-disorders-among-caregivers-of-hiv-infected-children-in-enugu-south-eastern-nigeria
#10
I F Ogbonna, I J Emodi, A N Ikefuna, N C Ojinnaka
Background: Nigeria has the highest burden of paediatric HIV in the world. HIV infection may result in significant life stressors, on both the infected children and their caregivers. Methods: This included a hospital-based cross-sectional and comparative study. Subjects and controls who met the inclusion criteria were enrolled consecutively. Their socio-demographic variables were obtained and GHQ-28 was used to assess their psychosocial status. Results: A total of 154 caregivers of HIV-infected children (subjects) and 154 caregivers of HIV-negative children (controls) were enrolled into this study...
April 17, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29911576/symptoms-disabilities-and-life-satisfaction-five-years-after-whiplash-injuries
#11
Johan Styrke, Peter Sojka, Ulf Björnstig, Britt-Marie Stålnacke
Background Chronic whiplash-associated disorders (WADs) are often associated with social functioning problems and decreased ability to perform previous activities. This may lead to decreased life satisfaction, which is insufficiently studied in the context of whiplash injuries. Symptoms included in chronic WAD are similar to symptoms frequently reported by persons who have sustained mild traumatic brain injury (MTBI)/concussion. In cases of MTBI, the severity and number of symptoms have been suggested to have a diagnostic value...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29908030/cutaneous-involvement-in-an-8-year-old-boy-with-ras-associated-autoimmune-leucoproliferative-disorder-rald
#12
A Giacaman, A Bauzá Alonso, J A Salinas Sanz, J L Dapena Díaz, R Ramos Asensio, L Ferrés Ramis, M A Durán Pastor, A Martín-Santiago
Ras-associated autoimmune leucoproliferative disorder (RALD) is a nonmalignant syndrome associated with somatic KRAS mutations. We report a patient with RALD and cutaneous lesions, the first such case reported, to our knowledge. An 8-year-old boy presented with erythematous plaques on his face and body, along with lymphadenopathies and spleen enlargement without systemic symptoms. An increased number of monocytes were found in skin biopsy, peripheral blood and bone marrow (BM). Juvenile myelomonocytic leukaemia (JMML) was suspected...
June 16, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29905966/chromosomally-integrated-human-herpesvirus-6-in-the-japanese-population
#13
Hiroki Miura, Yoshiki Kawamura, Fumihiko Hattori, Kei Kozawa, Masaru Ihira, Tamae Ohye, Hiroki Kurahashi, Tetsushi Yoshikawa
OBJECTIVES: To elucidate an incidence and virological findings of chromosomally integrated human herpesvirus 6 (ciHHV-6) in Japanese population and analyzed an association between ciHHV-6 and a clinical manifestation of exanthema subitum (ES). METHODS: Real-time PCR was performed to determine HHV-6 DNA loads in 2347 cord blood samples from healthy neonates (cohort A), febrile children less than 5 years old (cohort B), and hematopoietic cell transplant recipients (cohort C)...
June 15, 2018: Journal of Medical Virology
https://www.readbyqxmd.com/read/29905621/early-life-somatic-complaints-longitudinal-associations-with-maternal-and-child-psychopathology
#14
Melissa L Engel, Dominika A Winiarski, Brooke L Reidy, Patricia A Brennan
OBJECTIVE: Somatic complaints, often associated with concurrent and future internalizing symptoms and disorders in adult samples, were examined longitudinally from preschool to school age in a sample of children at an increased familial risk for psychopathology. The behavioral correlates and sex differences of somatic complaints and the persistence of these complaints across early childhood were examined. METHOD: A longitudinal sample of 185 mothers completed a laboratory visit when children were preschool aged and an online follow-up when children were school aged...
June 13, 2018: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/29904161/from-exome-analysis-in-idiopathic-azoospermia-to-the-identification-of-a-high-risk-subgroup-for-occult-fanconi-anemia
#15
Csilla Krausz, Antoni Riera-Escamilla, Chiara Chianese, Daniel Moreno-Mendoza, Elisabet Ars, Osvaldo Rajmil, Roser Pujol, Massimo Bogliolo, Ignacio Blanco, Ines Rodríguez, Isabel Badell, Eduard Ruiz-Castañé, Jordi Surrallés
PURPOSE: In about 10% of patients affected by Fanconi anemia (FA) the diagnosis is delayed until adulthood, and the presenting symptom in these "occult" FA cases is often a solid cancer and cancer treatment-related toxicity. Highly predictive clinical parameter(s) for diagnosing such an adult-onset cases are missing. METHODS: (1) Exome sequencing (ES), (2) Sanger sequencing of FANCA, (3) diepoxybutane (DEB)-induced chromosome breakage test. RESULTS: ES identified a pathogenic homozygous FANCA variant in a patient affected by Sertoli cell-only syndrome (SCOS) and in his azoospermic brother...
June 14, 2018: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/29902052/-loneliness-predicts-self-reported-cold-symptoms-after-a-viral-challenge-correction-to-leroy-et-al-2017
#16
(no author information available yet)
Reports an error in "Loneliness predicts self-reported cold symptoms after a viral challenge" by Angie S. LeRoy, Kyle W. Murdock, Lisa M. Jaremka, Asad Loya and Christopher P. Fagundes ( Health Psychology , 2017[May], Vol 36[5], 512-520). The erratum reports the following acknowledgments that were partially omitted from the author note: Data used in this article were collected by the Laboratory for the Study of Stress, Immunity, and Disease. The data were accessed via the Common Cold Project website...
July 2018: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/29900567/somatic-symptoms-of-anxiety-and-suicide-ideation-among-treatment-seeking-youth-with-anxiety-disorders
#17
Erika A Crawford, Taylor A Burke, David Siegel, Shari Jager-Hyman, Lauren B Alloy, Philip C Kendall
OBJECTIVE: The severity of anxiety, in general, has been associated with suicide ideation (SI) among youth, but research has yet to examine the specific anxiety symptoms that may contribute to SI among youth. This study examined the severity of specific anxiety symptom clusters (i.e., tense/restless, somatic/autonomic symptoms, humiliation/rejection, performing in public, separation anxiety, perfectionism, and anxious coping) and SI in youth who met diagnostic criteria for an anxiety disorder...
June 14, 2018: Suicide & Life-threatening Behavior
https://www.readbyqxmd.com/read/29899452/targeted-therapy-in-patients-with-pik3ca-related-overgrowth-syndrome
#18
Quitterie Venot, Thomas Blanc, Smail Hadj Rabia, Laureline Berteloot, Sophia Ladraa, Jean-Paul Duong, Estelle Blanc, Simon C Johnson, Clément Hoguin, Olivia Boccara, Sabine Sarnacki, Nathalie Boddaert, Stephanie Pannier, Frank Martinez, Sato Magassa, Junna Yamaguchi, Bertrand Knebelmann, Pierre Merville, Nicolas Grenier, Dominique Joly, Valérie Cormier-Daire, Caroline Michot, Christine Bole-Feysot, Arnaud Picard, Véronique Soupre, Stanislas Lyonnet, Jeremy Sadoine, Lotfi Slimani, Catherine Chaussain, Cécile Laroche-Raynaud, Laurent Guibaud, Christine Broissand, Jeanne Amiel, Christophe Legendre, Fabiola Terzi, Guillaume Canaud
CLOVES syndrome (congenital lipomatous overgrowth, vascular malformations, epidermal naevi, scoliosis/skeletal and spinal syndrome) is a genetic disorder that results from somatic, mosaic gain-of-function mutations of the PIK3CA gene, and belongs to the spectrum of PIK3CA-related overgrowth syndromes (PROS). This rare condition has no specific treatment and a poor survival rate. Here, we describe a postnatal mouse model of PROS/CLOVES that partially recapitulates the human disease, and demonstrate the efficacy of BYL719, an inhibitor of PIK3CA, in preventing and improving organ dysfunction...
June 13, 2018: Nature
https://www.readbyqxmd.com/read/29899299/parent-attributions-of-ambiguous-symptoms-in-their-children-a-preliminary-measure-validation-in-parents-of-children-with-chronic-pain
#19
Lauren C Heathcote, Sara E Williams, Allison M Smith, Christine B Sieberg, Laura E Simons
How parents attribute cause to their child&rsquo;s physical symptoms is likely important in understanding how the parent responds to the child, as well as the child&rsquo;s health outcomes, especially within the context of chronic illness. Here, we adapt the Symptom Interpretation Questionnaire for parent report (SIQ-PR) and provide preliminary validation in a sample of parents of children with chronic pain ( N = 311). Confirmatory factor analysis revealed that the SIQ-PR structure is consistent with the original measure, with three distinct attribution types: psychological (emotional/affective), somatic (illness/disease), and environmental (situational/transient) causes...
June 13, 2018: Children
https://www.readbyqxmd.com/read/29896052/somatic-symptoms-of-depression-and-anxiety-in-people-with-multiple-sclerosis
#20
Salene M W Jones, Rana Salem, Dagmar Amtmann
Background: People with multiple sclerosis (MS) are at increased risk for depression and anxiety. The symptoms of MS are often similar to the somatic or physical symptoms of depression and anxiety (fatigue, trouble concentrating). This study examined whether MS symptoms and effects biased the assessment of somatic symptoms of anxiety and depression. Methods: People with MS (n = 513) completed a survey about MS symptoms, treatments, and distress. The Patient Health Questionnaire-9 assessed depression, and the patient-report version of the Primary Care Evaluation of Mental Disorders assessed anxiety...
May 2018: International Journal of MS Care
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