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https://www.readbyqxmd.com/read/28717335/evaluation-of-therapeutic-effectiveness-of-prescribed-medications-in-patients-with-type-2-diabetes-mellitus-findings-from-a-tertiary-care-hospital-lahore-pakistan
#1
Bareera Rana, Allah Bukhsh, Tahir Mehmood Khan, Ammar Sarwar, Muhammad Ovais Omer, Shazia Qasim Jamshed
AIM: The present study was aimed to highlight the current prescribing pattern of oral hypoglycemia in type 2 diabetes mellitus and to evaluate the therapeutic effectiveness of these therapeutic categories in achieving target glycemic control. METHODS: This is a prospective, cross-sectional, observational study of 6 months' duration conducted in a tertiary care hospital of Lahore, Pakistan. RESULTS: The current research recruited 145 patients presented in diabetes management center of a tertiary care hospital in Lahore, Pakistan...
April 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28714405/emerging-targets-to-relieve-fat-stress-induced-liver-diseases-udca-tocotrienol-%C3%AF-3-pufas-and-igy-targeted-npc1l1-cholesterol-transporter
#2
Ji-Young Cha, Jong-Min Park, Ho-Jae Lee, Jin-Sik Bae, Young-Min Han, Byung-Chul Oh, Kwang Hyun Ko, Ki-Baik Hahm
Fat stress-induced liver disease is a hepatic manifestation of metabolic syndrome initiated by excess fat accumulation and encompasses a wide spectrum of diseases from non-alcoholic fatty liver disease to non-alcoholic steatohepatitis, a precursor lesion progressing to more aggressive liver cirrhosis and hepatocellular carcinoma. Although the incidence of these fat stress-induced liver diseases is rapidly increasing worldwide in parallel with the growing epidemics of obesity and metabolic diseases, its exact pathogenesis is not well defined...
July 14, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28706360/osteoporosis-prevention-and-management
#3
Muralidhar V Pai
Osteoporosis, defined by BMD at the hip or lumbar spine that is less than or equal to 2.5 standard deviations below the mean BMD of a young-adult reference population, is the most common bone disease in humans affecting both sexes and all races. It's a silent killer affecting the quality of life due to fractures and postural changes. In osteoporosis there is an imbalance between bone formation and bone resorption in favor of latter. Preventive measures and treatments are available to combat this evil. Counseling is the integral part of prevention as well as treatment of osteoporosis...
August 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/28701081/gut-microbiota-dysbiosis-associated-with-glucose-metabolism-disorders-and-the-metabolic-syndrome-in-older-adults
#4
K Lippert, L Kedenko, L Antonielli, I Kedenko, C Gemeier, M Leitner, A Kautzky-Willer, B Paulweber, E Hackl
Obesity and associated metabolic disorders have become highly prevalent diseases worldwide, and the human gut microbiota, due to its influence on host energy metabolism, has been attributed an important role therein. This pilot study explores host-microbiota relationships in men and women affected by various types of glucose metabolism disorder. Among 20 individuals aged 58 to 71 years with either normal glucose tolerance, prediabetes, or type 2 diabetes mellitus the gut bacterial communities were compared based on barcoded 454 sequencing of 16S rRNA genes amplified from stool samples...
July 13, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28698798/patients-expectations-and-fulfilment-of-expectations-before-and-after-treatment-for-suspected-coronary-artery-disease-assessed-with-a-newly-developed-questionnaire-in-combination-with-established-health-related-quality-of-life-questionnaires
#5
Annika Odell, Angela Bång, Paulin Andréll, Charlotte Widell, Henrik Fryklund, Anders Kallryd, Hans Tygesen, Lars Grip
BACKGROUND: Clinical decision-making is often based on evidence of outcome after a specific treatment. Healthcare providers and patients may, however, have different perceptions and expectations of what to achieve from a certain healthcare measure. AIMS: To evaluate patients' expectations, perceptions and health related quality of life (HRQoL) before a care process including coronary angiography for suspected coronary artery disease and to evaluate the fulfilment of these expectations in relation to established patient reported outcome measures (PROMs) 6 months later...
2017: Open Heart
https://www.readbyqxmd.com/read/28698162/galleria-mellonella-is-low-cost-and-suitable-surrogate-host-for-studying-virulence-of-human-pathogenic-vibrio-cholerae
#6
Habib Bokhari, Amjad Ali, Zobia Noreen, Nicholas Thomson, Brendan W Wren
Vibrio cholerae causes a severe diarrheal disease affecting millions of people worldwide, particularly in low income countries. V. cholerae successfully persist in aquatic environment and its pathogenic strains results in sever enteric disease in humans. This dual life style contributes towards its better survival and persistence inside host gut and in the environment. Alternative animal replacement models are of great value in studying host-pathogen interaction and for quick screening of various pathogenic strains...
July 8, 2017: Gene
https://www.readbyqxmd.com/read/28696041/the-contribution-of-microbial-biotechnology-to-sustainable-development-goals-microbiome-therapies
#7
Paul W O'Toole, Max Paoli
Complex communities of microbes live on and in plants, humans and other animals. These communities are collectively referred to as the microbiota or microbiome. Plants and animals evolved to co-exist with these microbes. In mammals, particular kinds of alteration of the microbiome (dysbiosis) are associated with loss of health, most likely due to loss of microbial metabolites, signalling molecules, or regulators of host pathways. Modern life-style diseases such as Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome (IBS), type 2 diabetes, obesity and metabolic syndrome have been linked to dysbiosis...
July 11, 2017: Microbial Biotechnology
https://www.readbyqxmd.com/read/28691532/is-the-effect-of-coping-styles-disease-specific-relationships-with-emotional-distress-and-quality-of-life-in-acquired-brain-injury-and-multiple-sclerosis
#8
Ingrid Brands, Yvonne Bol, Sven Stapert, Sebastian Köhler, Caroline van Heugten
OBJECTIVE: To investigate the use of coping styles and the relationships linking coping to emotional distress and quality of life in patients with acquired brain injury and multiple sclerosis. METHOD: Cross-sectional cohort study of 143 patients with acquired brain injury and 310 patients with multiple sclerosis in the chronic stage. Quality of life was measured with the Life Satisfaction Questionnaire (LiSat-9), coping styles with the Coping Inventory for Stressful Situations (CISS-T, task-oriented; CISS-E, emotion-oriented; CISS-A, avoidance), emotional distress with the Hospital Anxiety and Depression Scale (HADS)...
July 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28683811/the-prevalence-of-impaired-fasting-glucose-and-undiagnosed-diabetes-mellitus-and-associated-risk-factors-among-adults-living-in-a-rural-koladiba-town-northwest-ethiopia
#9
Abebaw Worede, Shitaye Alemu, Yalemzewod Assefa Gelaw, Molla Abebe
BACKGROUND: Diabetes mellitus is becoming a big public health challenge, particularly in developing countries like Ethiopia. It is a manageable disease if early screening and follow up is made. However, as studies in Ethiopia are limited and unorganized, determining the magnitude of prediabetes and diabetes and identifying associated risk factors is quite essential. METHODS: A community-based, cross-sectional study was conducted from February to April 2015 among adults (aged ≥20 years) in a rural Koladiba town...
July 6, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28679981/compliance-and-problems-with-the-surveillance-program-for-hcc-diagnosis
#10
Jun-Ichi Okano, Yukako Matsuki, Ran Nagahara, Masashi Yamane, Toshiaki Okamoto, Ken-Ichi Miyoshi, Tomomitsu Matono, Kenji Ohyama, Keiko Hosho, Hajime Isomoto
We conducted a multicenter retrospective study for evaluating the background of and diagnostic opportunity for 651 patients with primary hepatocellular carcinoma (HCC). The etiologies were hepatitis B virus (HBV) in 20.0% of patients, hepatitis C virus (HCV) in 36.3%, and non-B non-C (NBNC) in 43.5%. The characteristics of non-alcoholic NBNC HCC patients included low frequency of liver cirrhosis and high frequency of life style-related diseases. The mean diameter of HCC was approximately 4cm. Most patients were diagnosed using ultrasonography and dynamic computed tomography (CT)...
2017: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
https://www.readbyqxmd.com/read/28677522/population-engagement-and-consultation-at-the-local-level-thailand-experience
#11
Weerasak Putthasri, Nanoot Mathurapote, Orapan Srisookwattana
The World Health Organization handbook on Strategizing National Health in the 21st Century has emphasized the importance of the process of population consultation on needs and expectations. According to Thailand National Health Act 2007, three innovative social tools for participatory healthy public policy process were proposed, i.e., health assembly, health impact assessment and health system statute (charter). In practice, population consultation process is required in the process of the tools implementation...
2017: World Health & Population
https://www.readbyqxmd.com/read/28676037/challenges-and-outcomes-of-haemodialysis-among-patients-presenting-with-kidney-diseases-in-dodoma-tanzania
#12
Alfred J Meremo, David P Ngilangwa, Masumbuko Y Mwashambwa, Matobogolo B Masalu, Janet Kapinga, Rehema Tagalile, Issa Sabi
BACKGROUND: Kidney Diseases contribute a significant proportion to the global burden of non-communicable diseases. Haemodialysis services as the main modality of renal replacement therapy in most resource limited countries is only available in few cities and at higher costs. The aim of this study was to determine the challenges and outcomes of patients who were on haemodialysis at the University of Dodoma (UDOM) haemodialysis unit in Tanzania. METHODS: In this retrospective study; we reviewed haemodialysis registers and charts of 116 patients dialyzed from January 2013 to June 2015 at The UDOM haemodialysis unit...
July 4, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28666025/comparison-of-the-cba-h-and-sf-36-for-the-screening-of-the-psychological-and-behavioural-variables-in-chronic-dialysis-patients
#13
Concetta De Pasquale, Daniela Conti, Maria Luisa Pistorio, Pasquale Fatuzzo, Massimiliano Veroux, Santo Di Nuovo
The aim of the study was to perform an analysis of the emotional reactions, perception of stressful life and behavioural changes related to Haemodialysis (HD) in order to identify those variables that can improve lifestyle and the adherence to treatment. Some psychometric assessment, such as the Cognitive Behavioural Assessment, Hospital Form, (CBA-H) and the Health Survey (SF-36), which provides two indexes: the Physical Component Score (PCS) and the Mental Component Score (MCS), are suitable to assess a patient's psychological and behavioural style and their health-related quality of life...
2017: PloS One
https://www.readbyqxmd.com/read/28661907/behavioural-interventions-for-life-style-diseases-where-are-we-now
#14
Mohan Isaac, Winfried Rief
No abstract text is available yet for this article.
June 28, 2017: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/28659548/pathogenicity-of-enterococci
#15
Yasuyoshi Ike
Enterococci belong to the group of lactic acid bacteria (LAB), and inhabit the gastrointestinal tracts of a wide variety of animals from insects and to human, and the commensal organism in humans and animals. The commensal/probiotic role of enterococci has evolved through thousands of years in mutual coexistence. Enterococcus have many favorable traits that have been appreciated in food fermentation and preservation, and many serve as probiotics to promote health. While lactobacillus have been shown to confer numerous benefits on and often regarded as health bringing organisms, enterococci have become more recognized as emerging human pathogens in recent years...
2017: Nihon Saikingaku Zasshi. Japanese Journal of Bacteriology
https://www.readbyqxmd.com/read/28657472/evaluating-the-effects-of-exercise-on-cognitive-function-in-hypertensive-and-diabetic-patients-using-the-mental-test-and-training-system
#16
Robson Bonoto Teixeira, João Carlos Bouzas Marins, Paulo Roberto Santos Amorim, Israel Teoldo, Rocío Cupeiro, Marcelo Odilon Cabral de Andrade, Yuri de Lucas Xavier Martins, Pollyana de Rezende Castilho, Daniel Demétrio Magalhães, András Palotás, Luciana Moreira Lima
OBJECTIVES: Systemic arterial hypertension (SAH) and diabetes mellitus (DM) are important risk factors for developing cognitive impairment. General life-style changes including physical training are known to reduce elevated blood pressure and sugar levels, as well as improve mental health. The objective of this study was to evaluate whether supervised physical exercise enhances the cognitive status of patients with chronic diseases. METHODS: Volunteers with SAH, DM or SAH + DM participated in either aerobic or resistance training during a period of 12 weeks...
June 28, 2017: World Journal of Biological Psychiatry
https://www.readbyqxmd.com/read/28651010/macrophages-but-not-neutrophils-are-critical-for-proliferation-of-burkholderia-cenocepacia-and-ensuing-host-damaging-inflammation
#17
Jennifer Mesureur, Joana R Feliciano, Nelly Wagner, Margarida C Gomes, Lili Zhang, Monica Blanco-Gonzalez, Michiel van der Vaart, David O'Callaghan, Annemarie H Meijer, Annette C Vergunst
Bacteria of the Burkholderia cepacia complex (Bcc) can cause devastating pulmonary infections in cystic fibrosis (CF) patients, yet the precise mechanisms underlying inflammation, recurrent exacerbations and transition from chronic stages to acute infection and septicemia are not known. Bcc bacteria are generally believed to have a predominant extracellular biofilm life style in infected CF lungs, similar to Pseudomonas aeruginosa, but this has been challenged by clinical observations which show Bcc bacteria predominantly in macrophages...
June 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28647714/the-burden-of-multiple-sclerosis-and-patients-coping-strategies
#18
Lorena Lorefice, Giuseppe Fenu, Jessica Frau, Giancarlo Coghe, Maria Giovanna Marrosu, Eleonora Cocco
OBJECTIVES: Multiple sclerosis (MS) is a chronic disease that mainly affects young people. Patients with MS experience several emotional responses to changed perceptions of themselves and manage this situation in ways focused on controlling the overall burden of disease. This present study aimed to evaluate differences between patients with MS and healthy controls (HCs) in coping styles, identifying the MS clinical features that influence adaptive responses. METHODS: Patients with MS, according to the McDonald 2010 criteria, and HCs were recruited...
June 24, 2017: BMJ Supportive & Palliative Care
https://www.readbyqxmd.com/read/28646833/the-use-of-fruit-extracts-for-production-of-apple-chips-with-enhanced-antioxidant-activity
#19
Tomasz Tarko, Aleksandra Duda-Chodak, Dorota Semik-Szczurak
Background: Style and pace of life make consumers more willing to reach for snack products. This group of processed food includes, among others, fruit chips. Due to the increasing incidence of diseases associated with the excessive exposure to free radicals foods enriched with antioxidant compounds, eg. polyphenols, can be introduced into the sale. Objective: The aim of the study was to use the fruit extracts for the production of apple chips with enhanced antioxidant activity...
2017: Roczniki Państwowego Zakładu Higieny
https://www.readbyqxmd.com/read/28646832/diet-for-women-with-irritable-bowel-syndrome-a-preliminary-study
#20
Diana Wasiluk, Lucyna Ostrowska, Ewa Stefańska, Agnieszka Janke, Grażyna Jurkowska
Background: Irritable Bowel Syndrome (IBS) is one of the most frequent digestive system diseases, of various medical signs. It is assumed that proper life style, including appropriate, rational diet is a factor helpful for treating such a disorder. Objective: The purpose of this paper was to assess the selected dietary habits, and to evaluate the nutritional value of daily food rations for patients with a mixed type of Irritable Bowel Syndrome. Material and Methods: The questionnaire survey involved a group of 32 women suffering from a mixed type of Irritable Bowel Syndrome (The Rome III Diagnostic Criteria were used to diagnose the disease)...
2017: Roczniki Państwowego Zakładu Higieny
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