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https://www.readbyqxmd.com/read/28534002/purposeful-engagement-healthy-aging-and-the-brain
#1
Carol D Ryff, Aaron S Heller, Stacey M Schaefer, Carien van Reekum, Richard J Davidson
PURPOSE OF REVIEW: Research on psychological well-being in later life has identified strengths and vulnerabilities that occur with aging. We review the conceptual and philosophical foundations of a eudaimonic model of well-being and its empirical translation into six key dimensions of positive functioning. We also consider its implications for health, broadly defined. RECENT FINDINGS: Numerous findings from national longitudinal samples of U.S. adults are described...
December 2016: Current Behavioral Neuroscience Reports
https://www.readbyqxmd.com/read/28523254/effect-of-feelings-of-guilt-and-shame-on-life-quality-of-women-in-menopause
#2
Pelin Zivdir, Rabia Sohbet
OBJECTIVES: Current study was conducted between September 2014 and January 2015 in Gaziantep proviency Şehitkamil town Şirinevler district. Purpose of the study is to measure changes experienced, point of view on menopause, and life style of women who are older than 40, living in said district, and within post-menopause and how these factors effected their feelings of guilt and shame. METHODS: Out of universe consisting of 800 women, 500 participants have joined the study...
April 2017: Journal of Menopausal Medicine
https://www.readbyqxmd.com/read/28511414/a-community-based-study-on-pelvic-inflammatory-disease-in-postmenopausal-females-microbiological-spectrum-and-socio-demographic-correlates
#3
Samreen Khan, M Athar Ansari, Shaista M Vasenwala, Zehra Mohsin
INTRODUCTION: Pelvic Inflammatory Disease (PID) is a common and serious complication of sexually transmitted diseases in young women but is rarely diagnosed in the postmenopausal women. Very few studies have been done regarding post-menopausal PID. AIM: To determine the burden of PID, associated micro-organisms, pathophysiology and risk factors among post-menopausal women of the community. MATERIALS AND METHODS: A cross-sectional study was conducted among 530 post-menopausal women in the registered field practice areas of the JN Medical College and Hospital, Aligarh, Uttar Pradesh, India...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28510803/occupational-and-life-style-factors-acquired-mutagenicity-in-agric-workers-of-northeastern-brazil
#4
Tatiana Vieira Souza Chaves, Muhammad Torequl Islam, Manoel Odoríco de Moraes, Marcus Vinícius Oliveira Barros de Alencar, Débora Cássia Vieira Gomes, Rodrigo Mendes de Carvalho, Sharbel Weider Maluf, Fabrício Pires de Moura do Amaral, Márcia Fernanda Correia Jardim Paz, Gilberto Santos Cerqueira, Hercília Maria Lins Rolim, João Marcelo de Castro E Sousa, Ana Amélia de Carvalho Melo-Cavalcante, Maria Elisabete Amaral de Moraes
Pesticides are a complex mixture of chemicals used to protect crops from a number of pests and diseases. They have been considered as potential mutagenic agents. This study aims at evaluation of the mutagenic effect of pesticide exposure to agricultural workers through chromosomal aberrations (CA) and micronucleus (MN) assay in peripheral blood lymphocytes and oral mucosal cells, respectively. The exposed group was consisted with 97 farmers, while the control (un-exposed) group consisted of 55. The results showed a significant (p < 0...
May 16, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28502807/augmenting-brain-metabolism-to-increase-macro-and-chaperone-mediated-autophagy-for-decreasing-neuronal-proteotoxicity-and-aging
#5
REVIEW
Ben Loos, Daniel J Klionsky, Esther Wong
Accumulation of toxic protein aggregates in the nerve cells is a hallmark of neuronal diseases and brain aging. Mechanisms to enhance neuronal surveillance to improve neuronal proteostasis have a direct impact on promoting neuronal health and forestalling age-related decline in brain function. Autophagy is a lysosomal degradative pathway pivotal for neuronal protein quality control. Different types of autophagic mechanisms participate in protein handling in neurons. Macroautophagy targets misfolded and aggregated proteins in autophagic vesicles to the lysosomes for destruction, while chaperone-mediated autophagy (CMA) degrades specific soluble cytosolic proteins delivered to the lysosomes by chaperones...
May 11, 2017: Progress in Neurobiology
https://www.readbyqxmd.com/read/28493226/-etiology-and-pathophysiology-of-fibromyalgia-syndrome-updated-guidelines-2017-overview-of-systematic-review-articles-and-overview-of-studies-on-small-fiber-neuropathy-in-fms-subgroups
#6
N Üçeyler, M Burgmer, E Friedel, W Greiner, F Petzke, M Sarholz, M Schiltenwolf, A Winkelmann, C Sommer, W Häuser
BACKGROUND: The regular update of the guidelines on fibromyalgia syndrome, AWMF number 145/004, was planned for April 2017. METHODS: The guidelines were developed by 13 scientific societies and 2 patient self-help organizations coordinated by the German Pain Society. Working groups (n =8) with a total of 42 members were formed balanced with respect to gender, medical expertise, position in the medical or scientific hierarchy and potential conflicts of interest...
May 10, 2017: Der Schmerz
https://www.readbyqxmd.com/read/28480615/food-allergy-and-attitudes-to-close-interpersonal-relationships-an-exploratory-study-on-attachment
#7
Laura Polloni, Sami Schiff, Emilia Ferruzza, Francesca Lazzarotto, Roberta Bonaguro, Alice Toniolo, Nicolò Celegato, Muraro Antonella
BACKGROUND: Food allergy is a common immunological disease that includes potentially fatal reactions. It impacts considerably on patients' social life including close interpersonal relationships. Attachment theory provides a theoretical framework to evaluate the quality of close interpersonal relationships in chronic disorders. Attachment insecurity, mainly characterized by attachment avoidance, has been found in a variety of health conditions, but still needs to be investigated in food allergy...
May 8, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28479531/-structural-brain-development-in-healthy-children-and-adolescents
#8
Izumi Matsudaira, Ryuta Kawashima, Yasuyuki Taki
Brain maturation progresses throughout childhood into adolescence. Investigating the mechanism of brain development during these periods in healthy people is necessary for some clinical purposes. For example, these mechanisms are needed to investigate the mechanism of impaired brain maturation in neurodevelopmental disorders-such as autism spectrum disorders or attention-deficit hyper disorder-and improve early prevention of psychiatric or neurodegenerative diseases like depression or Alzheimer's disease. Voxel-based morphometry (VBM) is an effective way to analyze brain magnetic resonance images (MRI) of children and adolescents, as the brain structures of children and adolescents vary widely depending on their age, sex, and several other factors...
May 2017: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/28470370/high-dosage-of-a-fixed-combination-oxycodone-naloxone-prolonged-release-efficacy-and-tolerability-in-patients-with-chronic-cancer-pain
#9
Francesco Amato, Silvia Ceniti, Sergio Mameli, Giovanni M Pisanu, Renato Vellucci, Vincenzo Palmieri, Leonardo Consoletti, Dorotea Magaldi, Paolo Notaro, Claudio Marcassa
PURPOSE: Opioids are associated with side effects in the treatment of moderate-to-severe chronic cancer pain. Oral combination of opioid agonist-antagonist oxycodone-naloxone (OXN-PR) attenuates gastrointestinal side effects; however, evidence on high-dose OXN-PR treatment is scant. This study evaluates the efficacy and tolerability of high-dose OXN-PR in chronic cancer pain. PATIENTS AND METHODS: This was a multicenter, prospective 60-day observation on consecutive cancer patients with uncontrolled moderate-severe chronic pain or intolerant to other analgesics, who were switched at entry visit (T0) to OXN-PR ≥80 mg daily...
May 3, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28467327/presbiphonya
#10
Caterina Bruzzi, Daria Salsi, Domenico Minghetti, Maurizio Negri, Delfo Casolino, Michele Sessa
AIM: This article attempts to describe the aging process of the vocal folds and the main features of the aged voice. BACKGROUND: In the world ageing population era, aging diseases and aging disorders are crucial. Voice disorders (presbyphonia) are common in the elderly and have a significant impact on communication and quality of life. Some of these disorders depend on the vocal folds, which consist of an extracellular matrix (ECM), fibrous proteins, interstitial proteins, and glycosaminoglycans...
April 28, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/28458695/the-prevalence-of-low-physical-activity-in-an-urban-population-and-its-relationship-with-other-cardiovascular-risk-factors-findings-of-a-community-based-study-kercadrs-in-southeast-of-iran
#11
Hamid Najafipour, Mansoor Moazenzadeh, Mahdi Afshari, Hamid Reza Nasri, Mohammad Khaksari, Afsaneh Forood, Ali Mirzazadeh
BACKGROUND: The low physical activity (LPA) more or less affects every community. Because of high prevalence of cardiovascular diseases in Iran and their relationship with LPA, this study aimed to measure precisely the epidemic size of LPA and determine its relationship with six other coronary artery disease (CAD) risk factors among an urban population aged 15 to 75 years in Kerman, Iran. METHODS: Using household survey, 5895 adults were randomly recruited through single-stage cluster sampling from 250 postal codes...
September 2016: ARYA Atherosclerosis
https://www.readbyqxmd.com/read/28446527/the-value-of-different-aspects-of-person-centred-care-a-series-of-discrete-choice-experiments-in-people-with-long-term-conditions
#12
Christopher D Burton, Vikki A Entwistle, Alison M Elliott, Nicolas Krucien, Terry Porteous, Mandy Ryan
OBJECTIVE: To measure the value the patients place on different aspects of person-centred care. DESIGN: We systematically identified four attributes of person-centred care. We then measured their value to 923 people with either chronic pain or chronic lung disease over three discrete choice experiments (DCEs) about services to support self-management. We calculated the value of each attribute for all respondents and identified groups of people with similar preferences using latent class modelling...
April 26, 2017: BMJ Open
https://www.readbyqxmd.com/read/28438430/validation-of-simplified-indian-diabetes-risk-score-for-screening-undiagnosed-diabetes-in-an-urban-setting-of-haryana
#13
Meena Rajput, Dinesh Garg, Rajesh Rajput
BACKGROUND AND OBJECTIVES: Identification of at risk individuals using simple screening tools like Indian Diabetes Risk Score (IDRS) and appropriate life style interventions could greatly help in preventing or delaying the onset of diabetes and thus reducing the burden of disease. MATERIAL AND METHOD: 450 individuals >20years who consented to participate were selected randomly from three anganwadis of urban area of Rohtak city. Demographic characteristics and anthropometric measurements such as weight, height and waist circumference were taken...
April 2, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28437144/framingham-risk-score-and-estimated-10-year-cardiovascular-disease-risk-reduction-by-a-short-term-yoga-based-life-style-intervention
#14
Rashmi Yadav, Raj Kumar Yadav, Kumar Sarvottam, Ritesh Netam
OBJECTIVE: The aim of this study was to evaluate the efficacy of a short-term yoga-based life-style intervention program in lowering Framingham Risk Score (FRS) and estimated 10-year cardiovascular risk. METHODS: This was a single-arm, pre-post interventional study including data from a historical cohort with low to moderate risk for cardiovascular disease (CVD). It was conducted in a tertiary-care hospital. Participants with low (0 or 1 CVD risk factors) to moderately high risk (10-year risk between 10% and 20% and two or more CVD risk factors) were included...
February 16, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28436706/tobacco-use-and-attachment-style-in-appalachia
#15
Mary Heath Wise, Florence Weierbach, Yan Cao, Ken Phillips
Tobacco has been recognized as the number one cause of preventable death in America and results in almost 5.2 million years of potential life lost each year. The use of tobacco products is highly correlated with pulmonary disease, cardiovascular disease, and other forms of chronic illness in America. New tobacco products are trending in the tobacco market such as the water pipe/hookah and e-cigarettes. With e-cigarettes and other newer forms of tobacco on the rise, it is important to look at the underlying factors for using all kinds of tobacco products as a means of prevention...
April 24, 2017: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/28427561/molecular-targets-of-ascochlorin-and-its-derivatives-for-cancer-therapy
#16
Jason Chua Min-Wen, Benjamin Chua Yan-Jiang, Srishti Mishra, Xiaoyun Dai, Junji Magae, Ng Shyh-Chang, Alan Prem Kumar, Gautam Sethi
Cancer is an extremely complex disease comprising of a multitude of characteristic hallmarks that continue to evolve with time. At the genomic level, random mutations leading to deregulation of diverse oncogenic signal transduction cascades and polymorphisms coupled with environmental as well as life style-related factors are major causative agent contributing to chemoresistance and the failure of conventional therapies as well as molecular targeted agents. Hence, there is an urgent need to identify novel alternative therapies based on alternative medicines to combat this dreaded disease...
2017: Advances in Protein Chemistry and Structural Biology
https://www.readbyqxmd.com/read/28422120/trends-of-increases-in-potential-risk-factors-and-prevalence-rates-of-diabetes-mellitus-in-thailand
#17
REVIEW
V Chavasit, W Kriengsinyos, J Photi, K Tontisirin
Over the past three decades, undernutrition in Thailand has drastically reduced by over seven times. However, since 1995 the number of patients afflicted with non-communicable diseases, such as diabetes mellitus, has rapidly increased, even among the young. Unhealthy life styles due to urbanization are a major reason for this increase. Less physical activity and low consumption of fruits and vegetables, as well as high consumption of added free sugar, are common. Every year, the Thai people increase their consumption of energy from fat and protein, while lowering their intake of energy from complex carbohydrates...
April 19, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28417609/action-plans-and-coping-strategies-in-elderly-copd-patients-influence-the-result-of-pulmonary-rehabilitation-an-observational-study
#18
Patrizia Russo, Giulia Prinzi, Aliaksei Kisialou, Vittorio Cardaci, Emanuele Stirpe, Vittoria Conti, Massimo Fini, Stefano Bonassi
BACKGROUND: COPD management needs a comprehensive assessment of clinical features (symptoms severity, co-morbidities) together with life-style, behavioural, socio-economic and multi-omics parameters. Among the other issues, psycho-cognitive assessment plays a critical role. Coping strategies are used to manage psychological stress. AIM: To evaluate the association between coping strategies and outcome of Pulmonary Rehabilitation (PR). DESIGN: Observational study...
April 14, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28409233/effects-of-a%C3%A2-web-based-follow-up-intervention-on-self-efficacy-in-obesity-treatment-for-women
#19
Sonja Rader, Thomas Ernst Dorner, Rudolf Schoberberger, Hilde Wolf
Obesity is a chronic disease requiring long-term care. The purpose of the current study was the evaluation of a web-based intervention (WBI), subsequent to an initial face to face life style treatment. In a randomized trial, 84 women received an introduction phase (4 months) and a training phase (2 months) where one group was trained in using WBI whereas the other arm received a printed manual (PMI). During the self-monitoring phase (6 months) participants either used the WBI or the PMI for follow-up support...
April 13, 2017: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/28397944/prevalence-of-vitamin-d-deficiency-and-its-associated-factors-in-three-regions-of-saudi-arabia
#20
Ibrahim M Kaddam, Adnan M Al-Shaikh, Bahaa A Abaalkhail, Khalid S Asseri, Yousef M Al-Saleh, Ali A Al-Qarni, Ahmed M Al-Shuaibi, Waleed G Tamimi, Abdelmoneim M Mukhtar
To measure prevalence of vitamin D deficiency in Saudi Arabia, unveil the life style, nutritional habits and status, as well as identify the potential risk factors. Method: A school-based survey targeting Saudi school students and employees was conducted during the  period from 2013 to 2014 using multistage cluster random sample in Central, Western and Eastern regions. The prevalence of vitamin D deficiency and difference between various population subgroups were calculated. Logistic regression analysis was used to determine the predictors of potential risk factors...
April 2017: Saudi Medical Journal
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