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https://www.readbyqxmd.com/read/28930853/combined-resection-of-the-right-liver-lobe-and-retrohepatic-inferior-vena-cava-to-treat-hepatic-alveolar-echinococcosis-a-case-report
#1
Lei Du, Ling-Qiang Zhang, Li-Zhao Hou, Li Ren, Hai-Jiu Wang, Xin-Jian Guo, Haining Fan
RATIONALE: Hepatic alveolar echinococcosis (HAE) is a potentially fatal and chronically progressive infestation that is caused by the multivesicular metacestode of Echinococcus multilocularis (EM). HAE behaves like a malignant tumor and has been referred to as "worm cancer." The main treatment method for HAE is surgical resection. PATIENT CONCERNS: We present a 41-year-old Tibetan alveolar echinococcosis (AE) patient with AE lesions invading the right liver lobe and retrohepatic inferior vena cava (RHIVC)...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28929396/prevalence-of-echinococcus-granulosus-taeniasis-in-stray-dogs-in-the-region-of-constantine-north-east-algeria
#2
K Kohil, M C Benchikh El Fegoun, M Gharbi
In North Africa, the domestic dog is regarded as the main reservoir for infection by Echinococcus granulosus of domestic livestock and man. In Algeria, there is very little data on the rate of infestation of dogs, while the prevalence of E. granulosus in the definitive host is a very reliable marker of the potential risk of transmission of cystic tapeworm to humans and livestock. To find out this information, a survey was conducted to assess the prevalence of infection with E. granulosus in stray dogs in the region of Constantine (North-East Algeria)...
September 20, 2017: Bulletin de la Société de Pathologie Exotique
https://www.readbyqxmd.com/read/28919673/immunization-of-sheep-against-echinococcus-granulosus-with-protoscolex-tegumental-surface-antigens
#3
Manouchehr Valizadeh, Behzad Haghpanah, Alireza Badirzadeh, Elham Roointan, Shirzad Fallahi, Saber Raeghi
AIM: Cystic echinococcosis (CE) has potential economic effects to both animal products and human health. A vaccine to protect livestock against CE can be effective in reducing economic costs and increasing the livestock products. Protoscolex tegumental surface antigens (PSTSA) used to induce the production of specific antibodies against Echinococcus granulosus in sheep. The tegumental antigens were extracted from viable protoscolices by solubilization in sterile phosphate-buffered saline containing decanoyl-N-methylglucamine...
August 2017: Veterinary World
https://www.readbyqxmd.com/read/28915832/dogs-as-victims-of-their-own-worms-serodiagnosis-of-canine-alveolar-echinococcosis
#4
C F Frey, N Marreros, S Renneker, L Schmidt, H Sager, B Hentrich, S Milesi, B Gottstein
BACKGROUND: Besides acting as definitive hosts for Echinococcus multilocularis, dogs can become infected by the larval form of this parasite and thereby develop life-threatening alveolar echinococcosis (AE). Although AE is a zoonotic disease, most therapeutic and diagnostic approaches have been developed for human patients. In dogs, AE is typically diagnosed in the advanced stage of the disease when the parasitic mass has already caused abdominal distension. At that stage, complete resection of the parasitic mass is often impossible, leaving a guarded prognosis for the affected dogs...
September 16, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28915831/a-synoptic-overview-of-golden-jackal-parasites-reveals-high-diversity-of-species
#5
REVIEW
Călin Mircea Gherman, Andrei Daniel Mihalca
The golden jackal (Canis aureus) is a species under significant and fast geographic expansion. Various parasites are known from golden jackals across their geographic range, and certain groups can be spread during their expansion, increasing the risk of cross-infection with other carnivores or even humans. The current list of the golden jackal parasites includes 194 species and was compiled on the basis of an extensive literature search published from historical times until April 2017, and is shown herein in synoptic tables followed by critical comments of the various findings...
September 15, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28911334/slow-release-praziquantel-for-dogs-presentation-of-a-new-formulation-for-echinococcosis-control
#6
Bin Jiang, Xiao-Nong Zhou, Hao-Bing Zhang, Yi Tao, Le-Le Huo, Ni Liu
BACKGROUND: Echinococcosis is a serious, zoonotic, parasitic disease with worldwide distribution. According to a epidemiological survey in 2012 in China, there are 20,000 infected patients and more than 50 million people at the risk. As the dog is the main, definitive host, the Government of China encourages monthly praziquantel treatment of every dog. However, this is difficult to achieve in geographically challenging areas, such as the Tibetan plateau, where there are also many dogs without owners...
September 15, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28906255/echinococcus-multilocularis-vesicular-fluid-inhibits-activation-and-proliferation-of-natural-killer-cells
#7
Anne-Pauline Bellanger, Valentine Mougey, Jean-Rene Pallandre, Houssein Gbaguidi-Haore, Yann Godet, Laurence Millon
Alveolar echinococcosis is a severe chronic helminthic disease that mimics slow-growing liver cancer. The immune evasion strategy of Echinococcus multilocularis Leuckart, 1863 remains poorly understood. The aim of this study was to investigate in vitro the impact of E. multilocularis vesicular fluid (Em-VF) on peripheral blood mononuclear cells (PBMC) and on natural killer (NK) cells. PBMC and NK cells were exposed to Em-VF (1 µg/ml) during six days. The effect of Em-VF was assessed on CD69, viability and proliferation, and on and transforming growth factor β (TGF-β), interferon γ (IFN-γ), interleukin 17 (IL-17) and interleukin 10, using flow cytometry and ELISA, respectively...
August 25, 2017: Folia Parasitologica
https://www.readbyqxmd.com/read/28902565/molecular-cloning-and-characterization-of-ribosomal-protein-s9-in-echinococcus-granulosus
#8
Limei Wen, Guodong Lü, Shuai Lu, Huijing Gao, Bei Chen, Yunfang Ma, Yuan Yuan, Haibo Zhang, Yunfeng Xiao, Hui Liu, Jun Zhao, Jianhua Wang
Ribosomal protein S9 (RPS9) is an essential functional gene that participate in DNA repair and developmental regulations. A sequence homolog of RPS9 has been found to be upregulated in the protoscoleces (PSCs) of Echinococcus granulosus treated with artemisinin (ART). However, Echinococcus granulosus RPS9 (EgRPS9) has not been identified before. In the present study, the 657 bp cDNA encoding EgRPS9 was cloned. Amino acid sequence analysis showed that EgRPS9 was similar to the RSP9 proteins from Schistosoma japonicum (SjRPS9, 86 %) and Schistosoma mansoni (SmRPS9, 79 %)...
September 13, 2017: Journal of Parasitology
https://www.readbyqxmd.com/read/28902268/cystic-echinococcosis-in-south-america-a-call-for-action
#9
Carlos F Pavletic, Edmundo Larrieu, Eduardo A Guarnera, Natalia Casas, Pilar Irabedra, Ciro Ferreira, Julio Sayes, Cesar M Gavidia, Eduardo Caldas, Michael Laurence Zini Lise, Melody Maxwell, Marcos Arezo, Ana Maria Navarro, Marco A N Vigilato, Ottorino Cosivi, Marcos Espinal, Victor J Del Rio Vilas
Cystic echinococcosis (CE) or hydatidosis, a parasitic zoonosis caused by a cestode of the family Taeniidae, species Echinococcus granulosus, is endemic in Argentina, Chile, Peru, Uruguay, and southern Brazil. This report presents CE figures for these five countries in 2009 - 2014 and proposes indicators to measure national control programs. Nearly 5 000 new CE cases were diagnosed annually in the five countries during the study period. The average case fatality rate was 2.9%, which suggests that CE led to approximately 880 deaths in these countries during the 6-year period...
August 21, 2017: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28900448/scolicidal-agents-for-protoscolices-of-echinococcus-granulosus-hydatid-cyst-review-of-literature
#10
REVIEW
Seyedeh Maryam Sharafi, Raheleh Rafiei Sefiddashti, Behnam Sanei, Morteza Yousefi, Hossein Yousofi Darani
Hydatid cyst is the larval stage of dog tape worm Echinococcus granulosus. Protoscolices are parasite larvae that develop into adult worms in the final host intestine. During surgical treatment of human hydatidsosis spillage of live protoscolices is the major cause of hydatidosis recurrence. To prevent this problem scolicidal agent such as hypertonic salt are used to kill the protoscolices that may disseminate into the patient's tissues during surgery. However, they may have some unacceptable side effects. To find scolicidal agents with high efficacy, the effect of different compounds on protoscolices of hydatid cyst in vitro has been reviewed...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/28898797/scarless-surgery-for-a-huge-liver-cyst-a-case-report
#11
Hiroyuki Kashiwagi, Jun Kawachi, Naoko Isogai, Masanori Ishii, Katsunori Miyake, Rai Shimoyama, Ryota Fukai, Hidemitsu Ogino
INTRODUCTION: Symptomatic or complicated liver cysts sometimes require surgical intervention and laparoscopic fenestration is the definitive treatment for these cysts. We performed minimally invasive surgery, hybrid natural orifice transluminal endoscopic surgery (NOTES) without scarring, for a huge liver cyst. PRESENTATION OF CASE: An 82-year-old female presented with a month-long history of right upper abdominal pain. We diagnosed her condition as a huge liver cyst by morphological studies...
September 1, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28894716/seroprevalence-of-igg-antibodies-against-echinococcus-granulosus-by-elisa-method-using-recombinant-agb-in-lorestan-province-western-iran
#12
Vahid Fallah Omrani, Soheila Rouhani, Bahram Kazemi, Seyyed Javad Seyyedtabaei, Farnaz Kheirandish, Maysam Rezapour
BACKGROUND: Cystic echinococcosis (CE) is a zoonotic disease with global prevalence, which causes considerable health problems and economic losses throughout the world. The aim of this study was to assess the seroepidemiology of CE in Doroud City, Lorestan Province, Iran, considered a neglected endemic location. METHODS: An ELISA was performed using recombinant AgB from Apr to Jul 2015 in Lorestan Province, Western Iran. The commercial Hydatidosis IgG ELISA kit (Vircell SL, Granada, Spain) was used to confirm the obtained results...
August 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28894272/t-cell-tolerance-and-exhaustion-in-the-clearance-of-echinococcus-multilocularis-role-of-inoculum-size-in-a-quantitative-hepatic-experimental-model
#13
Chuanshan Zhang, Yingmei Shao, Shuting Yang, Xiaojuan Bi, Liang Li, Hui Wang, Ning Yang, Zhide Li, Cheng Sun, Liang Li, Guodong Lü, Tuerganaili Aji, Dominique A Vuitton, Renyong Lin, Hao Wen
The local immune mechanisms responsible for either self-healing or sustained chronic infection are not clear, in the development of E. multilocularis larvae. Here, we developed a suitable experimental model that mimics naturally infected livers, according to the parasite load. We demonstrated that local cellular immunity and fibrogenesis are actually protective and fully able to limit metacestode growth in the liver of low or medium dose-infected mice (LDG or MDG), or even to clear it, while impairment of cellular immunity is followed by a more rapid and severe course of the disease in high dose-infected mice (HDG)...
September 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28893673/extracorporeal-membrane-oxygenation-ecmo-as-salvage-treatment-for-pulmonary-echinococcus-granulosus-infection-with-acute-cyst-rupture
#14
Sören L Becker, Sebastian Fähndrich, Franziska C Trudzinski, Barbara Gärtner, Frank Langer, Torben K Becker, Robert Bals, Philipp M Lepper, Christian Lensch
Extracorporeal membrane oxygenation (ECMO) has been successfully used for the treatment of patients with respiratory failure due to severe infections. Though rare, parasites can also cause severe pulmonary disease. Tapeworms of the genus Echinococcus give rise to the development of cystic structures in the liver, lungs and other organs. Acute cyst rupture leads to potentially life-threatening infection, and affected patients may deteriorate rapidly. We describe the case of a young woman from Bulgaria who was admitted to hospital with severe dyspnoea, progressive chest pain and haemoptysis...
September 8, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28876584/hydatid-disease-in-south-africa-is-it-a-different-disease-in-patients-with-hiv-co-infection
#15
C Kloppers, K Couzens-Bohlin, M Bernon, S Burmeister, S Beningfield, U Kotze, J Krige, E Jonas
BACKGROUND: Echinococcus granulosus remains a clinical problem in rural sheep-farming communities, with HIV co-infection often seen in patients from endemic regions. METHOD: Data from a prospective database was used to identify patients with and without HIV co-infection that underwent surgery for hepatic hydatid disease between 2012 and 2017. Clinical presentation, preoperative intervention, surgical treatment, postoperative mortality and morbidity are reported according to the Accordion severity score...
September 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28876418/a-conventional-pcr-for-differentiating-common-taeniid-species-of-dogs-based-on-in-silico-microsatellite-analysis
#16
Saeedeh Shamsaddini, Mohammad Ali Mohammadi, Seyed Reza Mirbadie, Sima Rostami, Mansoureh Dehghani, Balal Sadeghi, Majid Fasihi Harandi
Canine taeniids are among the major tapeworms with remarkable medical and economic significance. Reliable diagnosis and differentiation of dog taeniids using simple and sensitive tools are of paramount importance for establishing an efficient surveillance system. Microsatellites as abundant unique tandem repeats of short DNA motifs are useful genetic markers for molecular epidemiological studies. The purpose of the present study was to find a primer pair for rapid differentiation of major tapeworms of dogs, Taenia hydatigena, T...
September 4, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28874087/systematic-investigations-of-gene-effects-on-both-topologies-and-supports-an-echinococcus-illustration
#17
Christophe Guyeux, Stéphane Chrétien, Nathalie M-L Côté, Jacques M Bahi
In this paper, we propose a high performance computing toolbox implementing efficient statistical methods for the study of phylogenies. This toolbox, which implements logit models and LASSO-type penalties, gives a way to better understand, measure, and compare the impact of each gene on a global phylogeny. As an application, we study the Echinococcus phylogeny, which is often considered as a particularly difficult example. Mitochondrial and nuclear genomes (19 coding sequences) of nine Echinococcus species are considered in order to investigate the molecular phylogeny of this genus...
August 16, 2017: Journal of Bioinformatics and Computational Biology
https://www.readbyqxmd.com/read/28870244/review-of-echinococcus-and-echinococcosis-part-a-edited-by-r-c-andrew-thompson-alan-j-lymbery-and-peter-deplazes
#18
Akira Ito
Thompson RCA, Deplazes P, Lymbery AJ, Editors. Echinococcus and Echinococcosis, Part A. Volume 95, Advances in Parasitology 95. Academic Press; 2017. 525 pages, ISBN 978-0-12-8114711 (hardcover); 9780128114728 (eBook).
September 4, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28859963/in-vitro-effects-of-amino-alcohols-on-echinococcus-granulosus
#19
Congshan Liu, Jianhai Yin, Jian Xue, Yi Tao, Wei Hu, Haobing Zhang
Cystic echinococcosis is a globally distributed zoonotic disease, which is caused by the larval stage of Echinococcosus granulosus sensu lato. The chemotherapy of the disease is limited to the use of benzimidazoles. Recently, mefloquine and its analogues, aminoalcohol-carbazole, and some amino alcohol derivatives were reported to display inhibitory effects on parasites. Here, the activities of 130 amino alcohol compounds against E. granulosus were tested on protoscoleces and germinal cells at a concentration of 20μg/ml over a period of three days...
August 28, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28842127/mechanistic-insights-into-eggst1-a-mu-class-glutathione-s-transferase-from-the-cestode-parasite-echinococcus-granulosus
#20
Paula Arbildi, Lucía Turell, Verónica López, Beatriz Alvarez, Verónica Fernández
Glutathione transferases (GSTs) comprise a major detoxification system in helminth parasites, displaying both catalytic and non-catalytic activities. The kinetic mechanism of these enzymes is complex and depends on the isoenzyme which is being analyzed. Here, we characterized the kinetic mechanism of rEgGST1, a recombinant form of a cytosolic GST from Echinococcus granulosus (EgGST1), which is related to the Mu-class of mammalian enzymes, using the canonical substrates glutathione (GSH) and 1-chloro-2,4-dinitrobenzene (CDNB)...
August 30, 2017: Archives of Biochemistry and Biophysics
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