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https://www.readbyqxmd.com/read/28531871/echinococcosis-mimicking-liver-malignancy-a-case-report
#1
Radek Pohnan, Miroslav Ryska, Vladislav Hytych, Radek Matej, Petr Hrabal, Jiri Pudil
INTRODUCTION: Human Alveolar Echinococcosis - Alveolar Hydatid disease (AE) is an omitted zoonotic infection presenting with focal liver lesions. Cause of AE is a larval stage of Echinococcus multilocularis tapeworms. CASE PRESENTATION: In this report an extraordinary case of a 38 year-old female examined due to 2 liver tumors and 2 pulmonary nodules is described. The patient underwent pulmonary and liver surgery for suspected advanced cholangiocellular carcinoma and surprisingly AE was found...
May 15, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28526606/identification-of-emsox2-a-member-of-the-sox-family-of-transcription-factors-as-a-potential-regulator-of-echinococcus-multilocularis-germinative-cells
#2
Zhe Cheng, Fan Liu, Mengya Dai, Jianjian Wu, Xiu Li, Xinrui Guo, Huimin Tian, Zhijie Heng, Ying Lu, Xiaoli Chai, Yanhai Wang
Larvae of the tapeworm Echinococcus multilocularis cause alveolar echinococcosis (AE), one of the most lethal helminthic infections in humans. The germinative cells, a population of stem cell-like cells, are considered to drive the continuous growth of the metacestodes within the host. The mechanisms and relative molecules controlling the behavior of germinative cells are poorly understood. Sox transcription factors play important roles in maintenance and regulation of stem/progenitor cells. We here describe the identification of a Sox family member in E...
May 17, 2017: International Journal for Parasitology
https://www.readbyqxmd.com/read/28526521/coexistence-of-aspergilloma-and-pulmonary-hydatid-cyst-in-an-immunocompetent-individual
#3
F Aala, H Badali, S Hashemi Fesharaki, M Boroumand, M Sotoudeh Anvari, H Davari, S Agha Kuchak Afshari, S Khodavaisy
Echinococcosis is a zoonotic disease caused by Echinococcus granulosus sensu lato. The liver and lungs are the most commonly sites of infections, but involvements of other organs were also observed. Recently, the coinfection of pulmonary hydatid cyst with aspergilloma has been reported in the literature. Herein, we report a successful treatment of coinfection of cystic echinoccosis with aspergilloma due to Aspergillus flavus in a 34-year-old female. In vitro antifungal susceptibility tests revealed that the MIC values for antifungals employed in this case were posaconazole (0...
May 16, 2017: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/28520724/development-of-a-movement-based-in-vitro-screening-assay-for-the-identification-of-new-anti-cestodal-compounds
#4
Dominic Ritler, Reto Rufener, Heinz Sager, Jacques Bouvier, Andrew Hemphill, Britta Lundström-Stadelmann
Intestinal cestodes are infecting millions of people and livestock worldwide, but treatment is mainly based on one drug: praziquantel. The identification of new anti-cestodal compounds is hampered by the lack of suitable screening assays. It is difficult, or even impossible, to evaluate drugs against adult cestodes in vitro due to the fact that these parasites cannot be cultured in microwell plates, and adult and larval stages in most cases represent different organisms in terms of size, morphology, and metabolic requirements...
May 17, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28507417/molecular-detection-of-taenia-spp-in-dogs-feces-in-zanjan-province-northwest-of-iran
#5
Mohammad Hasan Kohansal, Abbasali Nourian, Ali Haniloo, Asghar Fazaeli
AIM: Echinococcus and Taenia spp. are important but neglected zoonotic helminths of dogs. Dogs as the most relevant definitive hosts harbor several species of Taenia and Echinococcus simultaneously in their gastrointestinal lumen which are morphologically indistinguishable. In this study, we used a multiplex polymerase chain reaction (PCR) method to identify Taeniid infections which seem to be highly distributed in the study region. MATERIALS AND METHODS: A total of 450 dog fecal samples were collected from eight different areas of Zanjan province, northwest of Iran, and examined using a flotation method followed by multiplex PCR for detection and identification of parasites' eggs...
April 2017: Veterinary World
https://www.readbyqxmd.com/read/28507413/prevalence-of-echinococcosis-and-taenia-hydatigena-cysticercosis-in-slaughtered-small-ruminants-at-the-livestock-wildlife-interface-areas-of-ngorongoro-tanzania
#6
M B Miran, A A Kasuku, E S Swai
AIM: Echinococcosis or hydatidosis (due to the larval stage of Echinococcus spp.) and cysticercosis (due to the larval stage of Taenia hydatigena) pose a significant economic losses due to slaughter condemnation and risk to public health in developing countries such as Tanzania where sanitation is poor and people live in close proximity with each other and with animals. This study was conducted to determine the prevalence of and to identify the predisposing factors for echinococcosis and cysticercosis in sheep and goats at three slaughter slabs located in the livestock-wildlife interface areas of Ngorongoro, Tanzania...
April 2017: Veterinary World
https://www.readbyqxmd.com/read/28503283/cryptogenic-hepatitis-simulating-cyst-rupture-and-hydatid-jaundice-in-a-patient-with-preexisting-asymptomatic-hydatid-cyst
#7
Ulas Aday, Cuneyt Kayaalp, Murat Kapan
BACKGROUND: Rupture into the biliary ducts is the most frequent complication of hydatid liver disease. In endemic areas of Echinococcus granulosus, development of jaundice in a patient with liver cyst is initially suspected to have hydatid cyst. CASE PRESENTATION: A 48 year-old woman with history of asymptomatic hydatid liver cysts was admitted to the emergency department with right upper quadrant abdominal pain, increased levels of liver enzymes, bilirubin and alkaline phosphatase and the initial clinical diagnosis was the hydatid cyst rupture into the bile ducts...
2017: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/28499031/primary-echinococcus-infection-of-the-heart-a-rare-type-of-cystic-echinococcosis
#8
T N C Padmanabhan, K V K Kumar, Mohammed Sadiq Azam, Anil Kumar Bilolikar
No abstract text is available yet for this article.
May 12, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28494818/is-there-echinococcosis-in-west-africa-a-refugee-from-niger-with-a-liver-cyst
#9
Andrea Angheben, Mara Mariconti, Monica Degani, Maria Gobbo, Loredana Palvarini, Federico Gobbi, Enrico Brunetti, Francesca Tamarozzi
BACKGROUND: Italy is presently facing an increase in immigration from sub-Saharan Africa through the Mediterranean Sea. Case reports of human cystic echinococcosis (CE) have been reported from most sub-Saharan countries. Therefore, an increase in the number of patients with CE coming from these areas in the Italian and European centers for infectious diseases is expected. Unfortunately, the epidemiology of CE in sub-Saharan countries is poorly known, which makes clinical suspicion and diagnosis of such infection difficult in patients coming from these areas...
May 11, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28492796/a-concomitant-intramyocardial-and-pulmonary-hydatid-cyst-a-rare-case-report
#10
Harsh Sateesh Seth, Prashant Mishra, Jayant V Khandekar, Chaitanya Raut, Chandan Kumar Ray Mohapatra, Ganesh Kumar K Ammannaya
Cardiac hydatid cyst is an uncommon but potentially fatal disease. In cystic Echinococcus humans are an accidental host. Liver and lungs are the most frequently involved organs. Herein a unique case of intramyocardial hydatid cyst of left ventricle along with pulmonary hydatid cyst in a 38-year-old lady is reported. Surgical removal of the cardiac hydatid cyst was done with the aid of cardiopulmonary bypass followed by removal of pulmonary hydatid cyst.
March 2017: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28484564/hydatid-cysts-in-the-right-temporalis-muscle-an-exceptional-clinical-scenario
#11
Sanjeev Attry, Raghavendra Nayak, S K Saha, S N Ghosh
Hydatid diseases is a parasitic infestation of human and herbivorous animals caused by a cestode, Echinococcus granulosus, which resides in the intestine of definitive hosts like dogs and some wild carnivores like foxes. Liver and lung are commonly involved organs and involvement of muscles and bones is very unusual. Hydatid cyst of the temporalis muscle is extremely rare, even in the countries where echinococcal infestation is endemic. We report a case of 23-year-old female patient with a cystic swelling in the right temporalis muscle which turned out to be hydatid cysts...
April 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28480835/case-series-study-of-hepatic-echinococcal-cysts-in-serbia-viability-of-scolices-seropositivity-and-epidemiological-characteristics
#12
I Colovic Calovski, A Barac, Z Golubovic, A Karamarkovic, S Mitrovic, M Milicevic, M Cvetkovic, A M Dzamic
Cystic echinococcosis (CE) is an endemic helminthic disease caused by infection with Echinococcus granulosus metacestodes. Although CE is endemic in the Balkan region, the exact epidemiology remains unknown. We conducted a case-series study with the aim of evaluating the correlation between seropositivity, socio-epidemiological data, pre-operative treatment with albendazole and viability of protoscolices in human hepatic hydatid cysts. Consecutive patients with hepatic CE underwent surgery to extract E. granulosis cysts...
May 8, 2017: Journal of Helminthology
https://www.readbyqxmd.com/read/28464914/efficacy-of-radiotherapy-for-the-treatment-of-cystic-echinococcosis-in-naturally-infected-sheep
#13
Rui Mao, Wen-Bao Zhang, Hong-Zhi Qi, Tao Jiang, Ge Wu, Peng-Fei Lu, Abudula Ainiwaer, Ge Shang, Lin Xu, Jie Hao, Xi Shou, Hai-Tao Li, Jun Li, Song-An Zhang, Yong-Xing Bao, Hao Wen
BACKGROUND: Radiotherapy is commonly used to treat cancers. To date, there has been no study focusing on the effects of radiotherapy on hydatid disease in large animals. In this study, we aim to investigate the efficiency and safety of radiotherapy for treating hydatid disease caused by Echinococcus granulosus in naturally infected sheep. METHODS: Ultrasound was used to screen naturally infected sheep in an echinococcosis endemic area in Xinjiang, China. A computer tomography (CT) scan confirmed the presence of hydatid cysts...
May 3, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28463568/the-enzymatic-and-structural-basis-for-inhibition-of-echinococcus-granulosus-thioredoxin-glutathione-reductase-by-gold-i
#14
Gustavo Salinas, Wei Gao, Yang Wang, Mariana Bonilla, Long Yu, Andrei Novikov, Veridiana G Virginio, Henrique Ferreira, Marisol Vieites, Vadim N Gladyshev, Dinorah Gambino, Shaodong Dai
AIMS: New drugs are needed to treat flatworm infections that cause severe human diseases such as schistosomiasis. The unique flatworm enzyme thioredoxin glutathione reductase (TGR), structurally different from the human enzyme, is a key drug target. Structural studies of the flatworm Echinococcus granulosus TGR, free and complexed with AuI-MPO, a novel gold inhibitor, together with inhibition assays were performed. RESULTS: AuI-MPO is a potent TGR inhibitor that achieves 75% inhibition at a 1:1 TGR:Au ratio and efficiently kills E...
May 2, 2017: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/28459017/cystic-echinococcosis-a-neglected-disease-at-usual-and-unusual-locations
#15
Soma Sarkar, Himansu Roy, Puranjay Saha, Mallika Sengupta, Krisnendu Sarder, Manideepa Sengupta
Echinococcus granulosus causes a zoonotic infection called cystic echinococcosis (CE) or more commonly known as hydatid disease. Although the two most common locations of hydatid cyst are liver and lung, it may also appear in other parts of the body. Clinical presentation of the hydatid disease depends on the site and size of the lesion. A retrospective study was done in Medical College and Hospital, Kolkata, from January 2012 to June 2014, to find the site of involvement, distribution, clinical features, history of contact, mode of presentation, laboratory diagnosis, and treatment modalities of the cases of hydatid cyst...
January 2017: Tropical Parasitology
https://www.readbyqxmd.com/read/28457048/asymptomatic-presentation-of-large-cardiac-hydatid
#16
Amey Beedkar, Rohan Parikh, Pradeep Deshmukh
Hydatid cyst is a tissue parasitic infection caused by tapeworm Echinococcus granulosus. Common location for hydatid cysts are the liver (65%) and the lungs (25%). Cardiac hydatid cyst is seen rarely, occurring in about 0.5-2% of all cases of hydatid disease. We present this case of 45 years female who presented with short duration of dry cough and atypical chest pain. Chest X ray showed cardiomegaly with round bulge at the right heart border and curvilinear calcification in left upper abdomen in the region of spleen...
February 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28456662/new-mitogenome-and-nuclear-evidence-on-the-phylogeny-and-taxonomy-of-the-highly-zoonotic-tapeworm-echinococcus-granulosus-sensu-stricto
#17
Liina Kinkar, Teivi Laurimäe, Mitra Sharbatkhori, Hossein Mirhendi, Eshrat Beigom Kia, Francisco Ponce-Gordo, Vanessa Andresiuk, Sami Simsek, Antti Lavikainen, Malik Irshadullah, Gérald Umhang, Myriam Oudni-M'rad, Gerardo Acosta-Jamett, Steffen Rehbein, Urmas Saarma
Cystic echinococcosis, a zoonotic disease caused by Echinococcus granulosus sensu lato (s. l.), is a significant global public health concern. Echinococcus granulosus s. l. is currently divided into numerous genotypes (G1-G8 and G10) of which G1-G3 are the most frequently implicated genotypes in human infections. Although it has been suggested that G1-G3 could be regarded as a distinct species E. granulosus sensu stricto (s. s.), the evidence to support this is inconclusive. Most importantly, data from nuclear DNA that provide means to investigate the exchange of genetic material between G1-G3 is lacking as none of the published nuclear DNA studies have explicitly included G2 or G3...
April 27, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/28456598/two-haplotype-clusters-of-echinococcus-granulosus-sensu-stricto-in-northern-iraq-kurdistan-region-support-the-hypothesis-of-a-parasite-cradle-in-the-middle-east
#18
Zuber Ismael Hassan, Azad Abdullah Meerkhan, Belgees Boufana, Abdullah A Hama, Bayram Dawod Ahmed, Wijdan Mohammed Salih Mero, Serra Orsten, Maria Interisano, Edoardo Pozio, Adriano Casulli
Human cystic echinococcosis (CE) caused by Echinococcus granulosus s.s. is a major public health problem in Iraqi Kurdistan with a reported surgical incidence of 6.3 per 100,000 Arbil inhabitants. A total of 125 Echinococcus isolates retrieved from sheep, goats and cattle were used in this study. Our aim was to determine species/genotypes infecting livestock in Iraqi Kurdistan and examine intraspecific variation and population structure of Echinococcus granulosus s.s. in this region and relate it to that of other regions worldwide...
April 27, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28448863/multi-sited-hydatid-cystic-disease-with-muscular-involvement-in-a-young-female-a-case-report-from-syria
#19
Hazem Aljasem, Mohammad Almess, Monzer Bakgagi
INTRODUCTION: Hydatidosis is a unique disease caused by a tapeworm called Echinococcus granulosus. Musculoskeletal involvement with hydatid cystic disease accounts for less than 5% of all cases. The main purpose of this study is to present a case of multi-sited hydatid cystic disease and how to manage it. PRESENTATION OF CASE: Here we present a case of 14-year-old girl complained of a gradually enlarging mass on her left shoulder with a final diagnosis of triple-sited hydatid cystic disease including the right lung, the left trapezius muscle and the liver...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28443998/-detection-of-stool-antigens-of-echinococcus-granulosus-in-dogs-belonging-to-slaughterhouse-workers-and-offal-merchants-in-metropolitan-lima
#20
Veronika Merino, Néstor Falcón, Noelia Morel, Gualberto González
Objective: To demonstrate the presence of Echinoccocus granulosus in the definitive host in the city of Lima, Perú, by detecting parasite antigens in the stool of dogs belonging to offal handlers and merchants in authorized slaughterhouses in Metropolitan Lima. Methods: Stool samples were collected from 58 dogs and examined using the coproELISA technique for the detection of secretory/excretory antigens of E. granulosus. A survey was conducted to obtain information on pet feeding and handling practices...
April 20, 2017: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
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