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https://www.readbyqxmd.com/read/28329409/spiritual-aspects-of-living-with-infertility-synthesis-of-qualitative-studies
#1
REVIEW
Joana Romeiro, Sílvia Caldeira, Vivienne Brady, Fiona Timmins, Jenny Hall
AIM: To identify the spiritual aspects of patients experiencing infertility and seek a deeper and broader meaning of the involuntary childlessness experience. BACKGROUND: Infertility can be the cause for a spiritual crisis among some couples. Those who endure this involuntary childlessness condition frequently experience contradictory feelings and needs. In this context, core aspects of spirituality such as meaning and purpose in life are often questioned. DESIGN: A review and synthesis of qualitative empirical research was undertaken in order to seek a deeper understanding of the spiritual aspects of patients' experiences of infertility...
March 22, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28326521/anxiety-and-depression-in-women-undergoing-infertility-treatment
#2
Paulina Gdańska, Ewa Drozdowicz-Jastrzębska, Barbara Grzechocińska, Maria Radziwon-Zaleska, Piotr Węgrzyn, Mirosław Wielgoś
Infertility is a significant problem for millions of couples. Recently more attention is being paid to the relationship between infertility treatment with the use of Assisted Reproductive Techniques and the presence of mental disturbances, of which anxiety and depression are the most common. We present a review of recent studies evaluating the influence of anxiety and depression on fertility treatment outcomes and the effect of Assisted Reproductive Techniques treatment on the presence of anxiety and depression among women...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28325120/hydrosalpinx-tubal-surgery-or-in-vitro-fertilisation-an-everlasting-dilemma-nowadays-a-narrative-review
#3
A Daniilidis, D Balaouras, D Chitzios, T Theodoridis, E Assimakopoulos
The decision on how to treat tubal diseases, specifically hydrosalpinx, is a difficult one. Ιt involves surgical, medical, social, emotional and economic factors. This narrative review aims to increase awareness of tubal disease diagnosis and treatment, to compare between tubal surgery and in vitro fertilisation (IVF) for tubal factor infertility, and to investigate the effect of the combination of both. This way, we can be more effective, safe and provide our patients with better treatment results. The review analysed randomised studies, trials and meta-analysis, which give new aspects on the treatment methods for tubal pathology before IVF...
March 21, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28301256/sperm-epigenetics-in-the-study-of-male-fertility-offspring-health-and-potential-clinical-applications
#4
Timothy G Jenkins, Kenneth I Aston, Emma R James, Douglas T Carrell
The mammalian sperm contains a highly unique and specialized epigenetic landscape that offers a great degree of interesting research opportunities. One key discriminating feature of the mature sperm epigenome is that it, in theory, represents both remnant marks used throughout spermatogenesis to generate sperm cells competent to perform their function, but also marks that appear to be useful beyond fertilization. Key questions must be asked about the utility of these marks and the multiple purposes that may be served...
April 2017: Systems Biology in Reproductive Medicine
https://www.readbyqxmd.com/read/28289431/management-issues-of-congenital-adrenal-hyperplasia-during-the-transition-from-pediatric-to-adult-care
#5
REVIEW
Jin-Ho Choi, Han-Wook Yoo
Steroid 21-hydroxylase deficiency is the most prevalent form of congenital adrenal hyperplasia (CAH), accounting for approximately 95% of cases. With the advent of newborn screening and hormone replacement therapy, most children with CAH survive into adulthood. Adolescents and adults with CAH experience a number of complications, including short stature, obesity, infertility, tumor, osteoporosis, and reduced quality of life. Transition from pediatric to adult care and management of long-term complications are challenging for both patients and health-care providers...
February 2017: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/28289071/disorganization-of-the-germ-cell-pool-leads-to-primary-ovarian-insufficiency
#6
Ikko Kawashima, Kazuhiro Kawamura
The mammalian ovary is an organ that controls female germ cell development, storing them and releasing mature oocytes for transporting to the oviduct. During the fetal stage, female germ cells change from a proliferative state to meiosis before forming follicles with the potential for growth of surrounding somatic cells. Understanding of molecular and physiological bases of germ cell development in the fetal ovary contributed not only to the elucidation of genetic disorders in primary ovarian insufficiency (POI), but also advancement of novel treatments for patients with POI...
March 13, 2017: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/28285951/potential-role-of-green-tea-catechins-in-the-management-of-oxidative-stress-associated-infertility
#7
REVIEW
Shubhadeep Roychoudhury, Ashok Agarwal, Gurpriya Virk, Chak-Lam Cho
Reactive oxygen species (ROS) are present in low concentrations in the genital tracts of males and females. Excessive ROS lead to oxidative stress, which damages DNA, lipids and proteins. Such molecular changes result in compromised vitality, increased morphological defects and decreased sperm motility in the male. In the female, oxidative stress interferes with oocyte maturation, and may inhibit in-vitro maturation of the oocyte. Recently, green tea supplementation has been reported to possess properties that may improve the quality of male and female gametes largely due to the ability of catechin polyphenols to quench ROS...
February 27, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28280854/deficiency-in-sperm-egg-protein-interaction-as-a-major-cause-of-fertilization-failure
#8
REVIEW
Soudabeh Sabetian, Mohd Shahir Shamsir
Complete elucidation of fertilization process at molecular level is one of the unresolved challenges in sexual reproduction studies, and understanding the molecular mechanism is crucial in overcoming difficulties in infertility and unsuccessful in vitro fertilization. Sperm-oocyte interaction is one of the most remarkable events in fertilization process, and deficiency in protein-protein interactions which mediate this interaction is a major cause of unexplained infertility. Due to detection of how the various defects of sperm-oocyte interaction can affect fertilization failure, different experimental methods have been applied...
March 9, 2017: Journal of Membrane Biology
https://www.readbyqxmd.com/read/28280794/the-putative-effects-of-d-aspartic-acid-on-blood-testosterone-levels-a-systematic-review
#9
REVIEW
Farzad Roshanzamir, Seyyed Morteza Safavi
BACKGROUND: D-Aspartic acid (D-Asp) is in invertebrate and vertebrate neuroendocrine tissues, where it carries out important physiological functions. Recently, it has been reported that D-Asp is involved in the synthesis and release of testosterone and is assumed can be used as a testosterone booster for infertile men, and by athletes to increase muscle mass and strength. OBJECTIVE: The aim of this review is to summarize available evidence related to the effects of D-Asp on serum testosterone levels...
January 2017: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/28278534/transcription-and-splicing-factor-tdp-43-role-in-regulation-of-gene-expression-in-testis
#10
Prabhakara P Reddi
TDP-43 (TAR DNA binding Protein of 43 kD) is a transcription factor and RNA-binding protein with diverse functions. We cloned TDP-43 from the mouse testis in a screen for promoter-binding proteins and showed that it functions as a transcriptional repressor. TDP-43 plays a role in maintaining the precise pattern of spatiotemporal expression of the spermatid-specific Acrv1 gene during spermatogenesis by facilitating RNA polymerase II pausing at the promoter. We also showed that TDP-43 plays a partial role in preventing somatic cell expression of the Acrv1 gene by acting as an insulator-binding protein...
March 2017: Seminars in Reproductive Medicine
https://www.readbyqxmd.com/read/28278530/developmental-origins-of-hypothalamic-cells-controlling-reproduction
#11
Matthew Joseph Biehl, Lori Therese Raetzman
The hypothalamus-pituitary-gonadal (HPG) axis is the most critical modulator of reproductive function. Genetic or environmental insults to the HPG axis during developmental windows can persist into adulthood, and processes such as gonadal hormone synthesis, timing of puberty, and fertility can be affected. At the level of the hypothalamus, multiple regions develop at different times and are under the control of a concert of signaling pathways and transcription factors required for their patterning and maturation...
March 2017: Seminars in Reproductive Medicine
https://www.readbyqxmd.com/read/28277873/periodontal-disease-and-women-s-health
#12
Francesco Martelli, Maria Luisa Brandi, Marialaura Martelli, Piero Nobili, Enzo Medico, Maria Luisa Martelli
BACKGROUND: Periodontal disease (PD) is a multifactorial inflammatory condition in which inappropriate interaction between the host immune response and specific groups of bacterial pathogens leads to destruction of connective and bone tissues supporting the tooth. Dissemination of pathogens, toxins, and immune-complexes from and to periodontal lesions is at the basis of the increasingly recognized association between PD and various systemic diseases (SDs). Considering the growing attention of the medical community to "gender medicine", this review focuses on the association between PD and six systemic conditions heavily impacting women's health, with the aim of providing evidence in support of a joint effort between physicians and dentists to improve clinical management of these conditions...
February 20, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28270953/top-cited-articles-in-urology-from-turkey
#13
Tümay İpekçi, Mustafa Yüksel, Ahmet Tunçkıran
OBJECTIVE: Citation is the name given for a scientific publication in order to be used as a reference by another publication. In this study, we reviewed the most frequently cited publications in urology from Turkey. Although the number of citations is not completely definitive on its own, it shows the importance and effect of the publication. Besides the number of citations directly determines the impact factor of the journals and this factor is generally used in the evaluation of the quality and importance of the journal...
March 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28266237/frozen-embryo-transfer-cycles-in-women-with-deep-endometriosis
#14
George Queiroz Vaz, Alessandra Viviane Evangelista, Maria Cecilia Almeida Cardoso, Paulo Gallo, Maria Cecilia Erthal, Marco Aurelio Pinho Oliveira
OBJECTIVE: To compare the transfer pregnancy rates with frozen embryos from patients with deep endometriosis and non-endometriosis patients. METHODS: We conducted a retrospective cohort study of review of medical records of 181 women aged 18-40 years, undergoing transfer of frozen embryos into a fertility center. The data collected was from January 2007 to December 2013. RESULTS: Regarding the patients with endometriosis, there was no statistical difference in proportion to compare polycystic ovarian syndrome, male factor, tubal factor and unexplained infertility...
March 7, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28265850/a-general-description-for-chinese-medicine-in-treating-premature-ovarian-failure
#15
Jing Lin, Xue-Lian Li, Hui Song, Qian Li, Ming-Yan Wang, Xue-Min Qiu, Da-Jin Li, Ling Wang
Premature ovarian failure (POF) is a kind of gynecological disease that causes amenorrhea, infertility, menopause and urogenital symptoms. Currently hormone replacement therapy (HRT) is the most popular choice for women with POF to get rid of menopausal syndrome. However, as the popularization of Chinese herbs made Chinese medicine (CM) shine new lights, physicians are able to treat POF with both meno-herbs and integrated therapy. HRT has its own indications and contraindications. For example, unexplained vaginal bleeding, acute liver damage, liver dysfunction, vascular embolization, and breast cancer are all contraindications of HRT, and CM is taken by more physicians as an adjuvant therapy...
February 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28265313/cryptorchidism-a-practical-review-for-all-community-healthcare-providers
#16
REVIEW
Luis H Braga, Armando J Lorenzo
Cryptorchidism is one of the most common congenital anomalies of the male genitalia, occurring in 1% of boys by the age of one year. Even though the etiology of cryptorchidism is multifactorial, management has evolved with the clear recognition that hormonal treatment is not effective and surgery between 6-18 months of age leads to better testicular outcomes. Diagnostic laparoscopy is considered the standard approach for management of non-palpable testes, and can be combined with one or two-stage orchidopexy, with up to 80-90% success rates...
January 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28264433/the-effect-of-low-carbohydrate-diets-on-fertility-hormones-and-outcomes-in-overweight-and-obese-women-a-systematic-review
#17
Melanie McGrice, Judi Porter
(1) Background: Medical interventions including assisted reproductive technologies have improved fertility outcomes for many sub-fertile couples. Increasing research interest has investigated the effect of low carbohydrate diets, with or without energy restriction. We aimed to systematically review the published literature to determine the extent to which low carbohydrate diets can affect fertility outcomes; (2) Methods: The review protocol was registered prospectively with Prospective Register for Systematic Reviews (registration number CRD42016042669) and followed Preferred Reporting Items For Systematic Reviews and Meta-Analyses guidelines...
February 27, 2017: Nutrients
https://www.readbyqxmd.com/read/28261842/sperm-rna-preparation-for-transcriptomic-analysis-review-of-the-techniques-and-personal-experience
#18
S El Fekih, M-H Nguyen, A Perrin, D Beauvillard, F Morel, A Saad, H Ben Ali, M De Braekeleer
In the last 10 years, several approaches, including microarrays, have been applied to investigate sperm transcript levels. However, success using microarray profiling is highly dependent of the quality of the RNA obtained. Therefore, the development of methods that deliver highly purified and intact RNA is of utmost importance. The three steps used to achieve this goal, purification of spermatozoa, RNA extraction and evaluation of RNA quality, are reviewed. Following that review and preliminary experiments, we processed sperm samples from seven normozoospermic men with a combination of gradient centrifugation and somatic cell lysis...
March 6, 2017: Andrologia
https://www.readbyqxmd.com/read/28260557/the-influence-of-in-vitro-fertilization-and-embryo-culture-on-the-embryo-epigenetic-constituents-and-the-possible-consequences-in-the-bovine-model
#19
M-A Sirard
Medically assisted reproductive technologies, such as in vitro embryo production, are increasingly being used to palliate infertility. Eggs are produced following a hormonal regimen that stimulates the ovaries to produce a large number of oocytes. Collected oocytes are then fertilized in vitro and allowed to develop in vitro until they are either frozen or transferred to mothers. There are controversial reports on the adverse impacts of these technologies on early embryos and their potential long-term effects...
March 6, 2017: Journal of Developmental Origins of Health and Disease
https://www.readbyqxmd.com/read/28259808/the-effect-of-oral-phosphodiesterase-5-inhibitors-on-sperm-parameters-a-meta-analysis-and-systematic-review
#20
Ping Tan, Liangren Liu, Shiyou Wei, Zhuang Tang, Lu Yang, Qiang Wei
OBJECTIVE: To perform a systematic review and meta-analysis to evaluate the effect of phosphodiesterase-5 (PDE5) inhibitors on sperm parameters. METHODS: A systematic literature search was performed. Mean value and its standard deviation (mean ± standard deviation) were used to perform quantitative analysis. Statistic heterogeneity scores were assessed with the standard Cochran Q test and I(2) statistic. All statistical analyses were conducted by RevMan 5.3...
March 1, 2017: Urology
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