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Age at menarche

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https://www.readbyqxmd.com/read/28738458/-associations-between-season-of-birth-and-age-both-at-menarche-and-at-menopause
#1
J H Si, R R Meng, J Lyu, Y Guo, Z Bian, C Q Yu, L Yang, Y L Tan, P Pei, J S Chen, Z M Chen, L M Li
Objective: To examine the associations between season of birth and factors as age at menarche, age at menopause and reproductive span. Methods: A total of 285 186 female from the China Kadoorie Biobank, with complete data on critical variables and had menarche at 9-18 years old, were included. A total of 132 373 female with natural menopause were included for the analysis on age at menopause and reproductive span. Multiple linear regression models were used to assess the associations of birth season and the age at menarche, menopause, and reproductive span...
July 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28736691/prevalence-and-risk-factors-of-osteoporosis-among-jordanian-postmenopausal-women-attending-the-national-center-for-diabetes-endocrinology-and-genetics-in-jordan
#2
Dana Hyassat, Taghreed Alyan, Hashem Jaddou, Kamel M Ajlouni
To assess the prevalence of osteoporosis and osteopenia among Jordanian postmenopausal women attending the National Center for Diabetes, Endocrinology, and Genetics (NCDEG), and to determine the potential associated risk factors. A cross-sectional study was conducted at (NCDEG) in Amman, Jordan. A total of 1079 Jordanian postmenopausal women aged between 45 and 84 years were included in this study that was conducted during the period between April 2013 and December 2014. All patients underwent bone mineral density measurement through dual-energy X-ray absorptiometry (DEXA) scan...
2017: BioResearch Open Access
https://www.readbyqxmd.com/read/28732505/body-size-in-early-life-and-risk-of-breast-cancer
#3
Md Shajedur Rahman Shawon, Mikael Eriksson, Jingmei Li
BACKGROUND: Body size in early life is inversely associated with adult breast cancer (BC) risk, but it is unclear whether the associations differ by tumor characteristics. METHODS: In a pooled analysis of two Swedish population-based studies consisting of 6731 invasive BC cases and 28,705 age-matched cancer-free controls, we examined the associations between body size in early life and BC risk. Self-reported body sizes at ages 7 and 18 years were collected by a validated nine-level pictogram (aggregated into three categories: small, medium and large)...
July 21, 2017: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/28719421/lifelong-estradiol-exposure-and-risk-of-depressive-symptoms-during-the-transition-to-menopause-and-postmenopause
#4
Wendy K Marsh, Joyce T Bromberger, Sybil L Crawford, Katherine Leung, Howard M Kravitz, John F Randolph, Hadine Joffe, Claudio N Soares
OBJECTIVE: Depression risk increases during the menopausal transition (MT) and initial postmenopausal years-both times of significant fluctuations of estrogen. Research to date provides limited support for the hypothesis that estrogen fluctuations play a role in the greater susceptibility to midlife depression. Importantly, not all women report depressive symptoms during the MT, and recent reports suggest that duration of exposure to estradiol throughout the adult years may also play a role in vulnerability to depression...
July 17, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28716824/secular-trend-of-age-at-menarche-in-chinese-adolescents-born-from-1973-to-2004
#5
Xin Meng, Suyun Li, Wenhou Duan, Yanxin Sun, Chongqi Jia
OBJECTIVES: To estimate secular trend and factors influencing the age at menarche for Chinese girls born from 1973 to 2004. METHODS: Data were collected from the China Health and Nutrition Survey, a prospective open cohort and an ongoing nationwide health and nutrition survey, consisting of 3199 apparently healthy Chinese girls aged 6 to 18 years at entry from 1991 to 2011. Average age at menarche and its 95% confidence interval were estimated by weighted means of Kaplan-Meier survival analysis...
July 18, 2017: Pediatrics
https://www.readbyqxmd.com/read/28710506/obese-versus-normal-weight-late-adolescent-females-have-inferior-trabecular-bone-microarchitecture-a-pilot-case-control-study
#6
Joseph M Kindler, Norman K Pollock, Hannah L Ross, Christopher M Modlesky, Harshvardhan Singh, Emma M Laing, Richard D Lewis
Though still a topic of debate, the position that skeletal health is compromised with obesity has received support in the pediatric and adult literature. The limited data relating specifically to trabecular bone microarchitecture, however, have been relatively inconsistent. The aim of this pilot cross-sectional case-control study was to compare trabecular bone microarchitecture between obese (OB) and normal-weight (NW) late-adolescent females. A secondary aim was to compare diaphyseal cortical bone outcomes between these two groups...
July 14, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/28705605/age-of-menarche-is-associated-with-knee-joint-replacement-due-to-primary-osteoarthritis-the-hunt-study-and-the-norwegian-arthroplasty-register
#7
A I Hellevik, L Nordsletten, M B Johnsen, A M Fenstad, O Furnes, K Storheim, J A Zwart, G Flugsrud, A Langhammer
OBJECTIVE: To investigate whether parity, age at menarche, menopausal status, age at menopause, use of oral contraceptives (OC) or use of hormone replacement therapy (HRT) were associated with total knee replacement (TKR) or total hip replacement (THR) due to primary osteoarthritis. METHOD: In a prospective cohort study of 30,289 women from the second and third surveys of the Nord-Trøndelag Health Study, data were linked to the Norwegian Arthroplasty Register (NAR) in order to identify TKR or THR due to primary osteoarthritis...
July 10, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28704413/association-of-insulin-resistance-with-near-peak-bone-mass-in-the-femur-and-lumbar-spine-of-korean-adults-aged-25-35-the-korean-national-health-and-nutrition-examination-survey-2008-2010
#8
Min Soo Choo, Se Rin Choi, Jun Hyun Han, Seong Ho Lee, Young Suk Shim
OBJECTIVE: This study aimed to evaluate the relationship between insulin resistance and the bone mineral density (BMD) of femur and lumbar spine in Korean adults who are expected to exhibit near peak bone mass. METHODS: Data from the Korean National Health and Nutrition Examination Survey 2008-2010 were analyzed. A total of 2,750 participants aged 25-35 years were included. Insulin resistance was assessed using a homeostatic model assessment of insulin resistance (HOMA-IR) and serum fasting insulin...
2017: PloS One
https://www.readbyqxmd.com/read/28701499/breastfeeding-ovulatory-years-and-risk-of-multiple-sclerosis
#9
Annette Langer-Gould, Jessica B Smith, Kerstin Hellwig, Edlin Gonzales, Samantha Haraszti, Corinna Koebnick, Anny Xiang
OBJECTIVE: To determine whether women who breastfeed their infants longer or have fewer ovulatory years are at lower risk of developing multiple sclerosis (MS). METHODS: We recruited women with newly diagnosed MS or its precursor, clinically isolated syndrome (CIS) (n = 397), and matched controls (n = 433) into the MS Sunshine Study from the membership of Kaiser Permanente Southern California. A structured in-person questionnaire was administered to collect the behavioral (pregnancies, breastfeeding, hormonal contraceptive use) and biological (age at menarche and menopause, amenorrhea) factors to make up ovulatory years...
July 12, 2017: Neurology
https://www.readbyqxmd.com/read/28698185/age-at-menarche-and-late-adolescent-adiposity-associated-with-mammographic-density-on-processed-digital-mammograms-in-24-840-women
#10
Stacey E Alexeeff, Nnaemeka Odo, Jafi A Lipson, Ninah Achacoso, Joseph H Rothstein, Martin J Yaffe, Rhea Y Liang, Luana Acton, Valerie McGuire, Alice S Whitmore, Daniel L Rubin, Weiva Sieh, Laurel A Habel
BACKGROUND: High mammographic density is strongly associated with increased breast cancer risk. Some, but not all, risk factors for breast cancer are also associated with higher mammographic density. METHODS: The study cohort (N=24,840) was drawn from the Research Program in Genes, Environment and Health of Kaiser Permanente Northern California and included non-Hispanic white females aged 40-74 years with a full-field digital mammogram (FFDM). Percent density (PD) and dense area (DA) were measured by a radiological technologist using Cumulus...
July 11, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28676131/association-of-age-at-menopause-with-post-menopausal-symptoms-menarche-age-and-other-reproductive-factors-among-rural-females-in-shimla-himachal-pradesh
#11
Krishan Sharma, Mayuk Bansal
This study analysed the association between menopause, menarche and number of live births using cross-sectional primary data for 75 post-menopausal rural women from Shimla in the Indian state of Himachal Pradesh. The mean/median ages at menarche of the 75 women were 14.23/14 years, and those at menopause 45.35/45 years. There were no significant differences in these values between women in the age groups 40-55 and 56-65 years. Age at menopause was found to be significantly associated with age at menarche and maternal age at birth of the first and last child, but not with menopausal symptom severity score...
July 5, 2017: Journal of Biosocial Science
https://www.readbyqxmd.com/read/28672280/molecular-screening-of-mkrn3-dlk1-and-kcnk9-genes-in-girls-with-idiopathic-central-precocious-puberty
#12
Anna Grandone, Carlo Capristo, Grazia Cirillo, Marcella Sasso, Giuseppina Rosaria Umano, Michela Mariani, Emanuele Miraglia Del Giudice, Laura Perrone
BACKGROUND: Mutations in the imprinted gene MKRN3 have been described as a common genetic cause of idiopathic central precocious puberty (CPP), in particular in familial cases. However, the exact prevalence of mutations is unknown. Single nucleotide polymorphisms in 2 other imprinted genes, DLK1 and KCNK9, have been associated with age at menarche. We investigated the prevalence of mutations in MKRN3, DLK1, and KCNK9 genes in a cohort of girls with idiopathic CPP. METHODS: MKRN3, DLK1, and KCNK9 coding regions were sequenced in 60 girls with idiopathic CPP (familial in 23 cases)...
July 3, 2017: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/28670784/gene-environment-interactions-involving-functional-variants-results-from-the-breast-cancer-association-consortium
#13
Myrto Barrdahl, Anja Rudolph, John L Hopper, Melissa C Southey, Annegien Broeks, Peter A Fasching, Matthias W Beckmann, Manuela Gago-Dominguez, J Esteban Castelao, Pascal Guénel, Thérèse Truong, Stig E Bojesen, Susan M Gapstur, Mia M Gaudet, Hermann Brenner, Volker Arndt, Hiltrud Brauch, Ute Hamann, Arto Mannermaa, Diether Lambrechts, Lynn Jongen, Dieter Flesch-Janys, Kathrin Thoene, Fergus J Couch, Graham G Giles, Jacques Simard, Mark S Goldberg, Jonine Figueroa, Kyriaki Michailidou, Manjeet K Bolla, Joe Dennis, Qin Wang, Ursula Eilber, Sabine Behrens, Kamila Czene, Per Hall, Angela Cox, Simon Cross, Anthony Swerdlow, Minouk J Schoemaker, Alison M Dunning, Rudolf Kaaks, Paul D P Pharoah, Marjanka Schmidt, Montserrat Garcia-Closas, Douglas F Easton, Roger L Milne, Jenny Chang-Claude
Investigating the most likely causal variants identified by fine-mapping analyses may improve the power to detect gene-environment interactions. We assessed the interplay between 70 SNPs identified by genetic fine-scale mapping of susceptibility loci and 11 epidemiological breast cancer risk factors in relation to breast cancer. Analyses were conducted on up to 58,573 subjects (26,968 cases, 31,605 controls) from the Breast Cancer Association Consortium (BCAC), in one of the largest studies of its kind. Analyses were carried out separately for estrogen receptor positive (ER+) and estrogen receptor negative (ER-) disease...
July 3, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28669518/impact-of-interaction-between-ppar-alpha-and-ppar-gamma-on-breast-cancer-risk-in-the-chinese-han-population
#14
Xiong Lianggeng, Liang Baiwu, Bai Maoshu, Liu Jiming, Li Youshan
BACKGROUND: Several studies have been conducted to investigate the association of the peroxisome proliferator-activated receptor (PPAR) alpha (PPAR A) and PPAR gamma (PPAR G) polymorphism and breast cancer (BC) risk, but the results were inconsistent, and, until now, no study focused on the impact of gene-gene interactions between PPAR A and PPAR G on BC risk; thus, the aim of this study was to investigate the impact of interaction between PPAR A and PPAR G on BC risk in the Chinese Han population...
October 19, 2016: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28661938/age-at-pubertal-onset-in-girls-and-tobacco-smoke-exposure-during-pre-and-post-natal-susceptibility-windows
#15
Gayle C Windham, Raymond Lum, Robert Voss, Mary Wolff, Susan M Pinney, Susan L Teteilbaum, Connie S Sosnoff, Dina Dobraca, Frank Biro, Robert A Hiatt, Louise C Greenspan, Maida Galvez, Lawrence H Kushi
BACKGROUND: Tobacco smoke contains known hormonally active chemicals and reproductive toxicants. Several studies have examined prenatal maternal smoking and offspring age at menarche, but few examined earlier pubertal markers, nor accounted for exposure during childhood. Our objective was to examine pre- and post-natal smoke exposure in relation to timing of early pubertal events. METHODS: An ethnically diverse cohort of 1239 girls was enrolled at age 6-8 years for a longitudinal study of puberty at three U...
June 28, 2017: Epidemiology
https://www.readbyqxmd.com/read/28660685/studying-the-relationship-between-a-woman-s-reproductive-lifespan-and-age-at-menarche-using-a-bayesian-multivariate-structured-additive-distributional-regression-model
#16
Elisa Duarte, Bruno de Sousa, Carmen Cadarso-Suárez, Nadja Klein, Thomas Kneib, Vítor Rodrigues
Studies addressing breast cancer risk factors have been looking at trends relative to age at menarche and menopause. These studies point to a downward trend of age at menarche and an upward trend for age at menopause, meaning an increase of a woman's reproductive lifespan cycle. In addition to studying the effect of the year of birth on the expectation of age at menarche and a woman's reproductive lifespan, it is important to understand how a woman's cohort affects the correlation between these two variables...
June 29, 2017: Biometrical Journal. Biometrische Zeitschrift
https://www.readbyqxmd.com/read/28656365/bone-mineral-density-in-vocational-and-professional-ballet-dancers
#17
T Amorim, Y Koutedakis, A Nevill, M Wyon, J Maia, J C Machado, F Marques, G S Metsios, A D Flouris, N Adubeiro, L Nogueira, L Dimitriou
According to existing literature, bone health in ballet dancers is controversial. We have verified that, compared to controls, young female and male vocational ballet dancers have lower bone mineral density (BMD) at both impact and non-impact sites, whereas female professional ballet dancers have lower BMD only at non-impact sites. INTRODUCTION: The aims of this study were to (a) assess bone mineral density (BMD) in vocational (VBD) and professional (PBD) ballet dancers and (b) investigate its association with body mass (BM), fat mass (FM), lean mass (LM), maturation and menarche...
June 27, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28654008/exposure-to-perfluorinated-alkyl-substances-and-health-outcomes-in-children-a-systematic-review-of-the-epidemiologic-literature
#18
Kristen M Rappazzo, Evan Coffman, Erin P Hines
Perfluoroalkyl substances (PFAS), chemicals used to make products stain and stick resistant, have been linked to health effects in adults and adverse birth outcomes. A growing body of literature also addresses health effects in children exposed to PFAS. This review summarizes the epidemiologic evidence for relationships between prenatal and/or childhood exposure to PFAS and health outcomes in children as well as to provide a risk of bias analysis of the literature. A systematic review was performed by searching PubMed for studies on PFAS and child health outcomes...
June 27, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28645184/early-menarche-and-menstrual-problems-are-associated-with-sleep-disturbance-in-a-large-sample-of-chinese-adolescent-girls
#19
Xianchen Liu, Hua Chen, Zhen-Zhen Liu, Fang Fan, Cun-Xian Jia
Study Objectives: Little is known about the association between menstruation and sleep disturbance in adolescent girls. This study examined sleep duration, insomnia symptoms, and sleep quality in relation to age at menarche and menstrual problems in a large sample of Chinese adolescent girls. Methods: This report represents the baseline data of an ongoing longitudinal study of the Shandong Adolescent Behavior & Health Cohort (SABHC) in Shandong, China. 5,800 12 to 18-year-old girls (mean age= 15...
June 22, 2017: Sleep
https://www.readbyqxmd.com/read/28643020/association-between-lifestyle-menstrual-reproductive-history-and-histological-factors-and-risk-of-breast-cancer-in-women-biopsied-for-benign-breast-disease
#20
Rhonda Arthur, Yihong Wang, Kenny Ye, Andrew G Glass, Mindy Ginsberg, Olivier Loudig, Thomas Rohan
PURPOSE: Women with benign breast disease (BBD) have an increased risk of subsequent breast cancer. However, whether conventional breast cancer risk factors influence risk of breast cancer among women with BBD is unclear. In this study, we investigated the associations of lifestyle, menstrual/reproductive, and histological factors with risk of breast cancer among women biopsied for BBD. METHODS: We conducted a case-control study, nested within a cohort of 15,395 women biopsied for BBD at Kaiser Permanente Northwest between 1971 and 2006...
June 22, 2017: Breast Cancer Research and Treatment
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