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Palak M Majmudar, Felina Kremer, Nisha Chadha
To report a case of recurrent hypotony and choroidal effusion following trabeculectomy. OBSERVATIONS: A 70 year old male with advanced pseudoexfoliation glaucoma in both eyes underwent trabeculectomy in the left eye. Initially intraocular pressure (IOP) was controlled without topical therapy, but dorzolamide-timolol and brimonidine were added when IOP elevated above target. Aqueous suppressant glaucoma medications were thought to cause three episodes of hypotony resolving with discontinuation of these medications...
September 2018: American Journal of Ophthalmology Case Reports
Andreas F Borkenstein, Eva-Maria Borkenstein
Purpose: The purpose of this prospective analysis was to evaluate the patient and surgeon satisfaction levels after using a fully preloaded acrylic, hydrophobic, monofocal "premium" IOL in pseudoexfoliation syndrome. Materials and Methods: 42 eyes of twenty-eight patients with progressed cataract formation and pseudoexfoliation syndrome (PXF) or pseudoexfoliation glaucoma and best corrected distance visual acuity (BCDVA) between 0.30-1.00 logMAR were enrolled...
2018: Journal of Ophthalmology
Numan Eraslan, Ufuk Elgin, Emine Şen, Aytul Kilic, Pelin Yilmazbas
AIM: To investigate the levels of ghrelin (Gh), acylated ghrelin (AGh) and AGh/Gh ratio in the humor aqueous (HA) of cases with pseudoexfoliation syndrome (PXS), pseudoexfoliation glaucoma (PXG), primary open angle glaucoma (POAG) and to compare these with control subjects. METHODS: A prospective examination was made of the total Gh, and AGh levels in HA of 67 patients undergoing cataract surgery. Patients were divided into 4 groups. HA samples were aspirated at the beginning of the surgery, stored at -70°C...
2018: International Journal of Ophthalmology
Mehmet Kaygisiz, Ufuk Elgin, Kemal Tekin, Emine Sen, Pelin Yilmazbas
PURPOSE: To compare the anterior segment parameters of patients with pseudoexfoliation syndrome, patients with pseudoexfoliation glaucoma, and normal subjects. METHODS: This prospective, controlled, comparative study included 150 eyes of 150 patients. The patients were divided into the pseudoexfoliation syndrome group, the pseudoexfoliation glaucoma group, and the control group (50 patients in each group). Axial length, central corneal thickness, aqueous depth, anterior chamber depth, lens thickness, K1 and K2 keratometry values, and white to white distance measurements were obtained by optical biometry and compared between the groups...
April 2018: Arquivos Brasileiros de Oftalmologia
Constantine D Georgakopoulos, Olga E Makri
No abstract text is available yet for this article.
June 2018: Indian Journal of Ophthalmology
Andrei-Alexandru Szigiato, Simrenjeet Sandhu, Gokulan Ratnarajan, Michael W Dorey, Iqbal Ike K Ahmed
OBJECTIVE: To evaluate and compare the surgeon's learning experience with an ab-interno gelatin microstent (XEN-45, Allergan) to other glaucoma surgeries. DESIGN: Cross-sectional survey study. METHODS: All surgeons in Canada who used the gelatin microstent were identified and given an anonymous online survey (FluidSurveys, Survey Monkey) designed to evaluate key factors associated with the device, including prior surgical experience, patient selection criteria, analysis of each surgical step, and postoperative care...
June 2018: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
Ufuk Elgin, Emine Sen, Salih Çolak, Pelin Yılmazbas
PURPOSE: To investigate the outcomes of trabeculectomy with 5-fluorouracil (5-FU) with or without subconjunctival bevacizumab in the surgical management of pseudoexfoliation glaucoma (PXG). METHODS: This retrospective study consisted of 49 cases with PXG who underwent initial trabeculectomy with 5-FU. The cases were divided into two age- and sex-matched groups. In 23 cases, subconjunctival bevacizumab was injected (1.25 mg/0.05 mL) at the end of the surgery and in 26 of them the surgery was performed without bevacizumab...
April 25, 2018: International Ophthalmology
Muhammed Batur, Erbil Seven, Merhamet Tanrıkulu, Selami Ekin, Serek Tekin, Tekin Yasar
OBJECTIVES: It is well-known that pseudoexfoliative material deteriorates iris dilatation function. This material was also found in lung tissue. The aim of the study was to evaluate pulmonary function in patients with pseudoexfoliation. METHODS: This prospective study included 60 pseudoexfoliation syndrome patients without any pulmonary diseases and 52 age- and gender-matched controls without any pulmonary diseases. Patients were asked about their cigarette use and the presence of any systemic diseases such as diabetes mellitus, arterial hypertension and asthma...
April 16, 2018: Clinical Respiratory Journal
Niranjan Manoharan, Jennifer L Patnaik, Levi N Bonnell, Jeffrey R SooHoo, Mina B Pantcheva, Malik Y Kahook, Brandie D Wagner, Anne M Lynch, Leonard K Seibold
PURPOSE: To evaluate refractive outcomes after phacoemulsification cataract surgery in patients with glaucoma. SETTING: University of Colorado Health Eye Center, Aurora, Colorado, USA. DESIGN: Retrospective case series. METHODS: The incidence of refractive surprise was evaluated in patients with and without glaucoma after phacoemulsification cataract surgery. Refractive surprise was defined as the difference in spherical equivalent of the refractive target and postoperative refraction in diopters (D)...
March 2018: Journal of Cataract and Refractive Surgery
Anja-Maria Davids, Milena Pahlitzsch, Alexander Boeker, Necip Torun, Eckart Bertelmann, Anna-Karina Maier-Wenzel, Annette Hager, Johannes Gonnermann, Matthias Klamann
PURPOSE: The aim of this study is to assess the intraocular pressure lowering effect and the performance of the glaucoma therapy of the iStent inject in glaucoma patients with uncontrolled intraocular pressure after failed trabeculectomy. METHODS: In this retrospective study, iStent inject implantation (Glaukos Corporation, Laguna Hills, CA, USA) was performed in 22 eyes of 21 subjects suffering from glaucoma (n = 18 primary open angle glaucoma, n = 3 pseudoexfoliation glaucoma, and n = 1 for secondary glaucoma) with an intraocular pressure above target pressure after failed trabeculectomy (mean = 9...
March 1, 2018: European Journal of Ophthalmology
Kemal Tekin, Mehmet Ali Sekeroglu, Hasan Kiziltoprak, Esat Yetkin, Sibel Doguizi, Pelin Yilmazbas
PURPOSE: To perform a comparison of static and dynamic pupillometry measurements in patients with clinically unilateral pseudoexfoliation syndrome (PES) and age-matched controls. METHODS: This prospective cross-sectional study consisted of 38 patients with unilateral PES and 40 control participants. A quantitative pupillometry system was used to evaluate the pupil characteristics of eyes with PES (Group 1), clinically unaffected fellow eyes (Group 2), and healthy eyes (Group 3)...
March 23, 2018: Journal of Glaucoma
Jost B Jonas, Wen Bin Wei, Li Ping Zhu, Liang Xu, Ya Xing Wang
To examine associations between cognitive function and ophthalmological parameters, the population-based Beijing Eye Study examined ophthalmologically and physically 3127 individuals (mean age: 64.2 ± 9.8 years). Using the mini-mental state examination, cognitive function was assessed as cognitive function score (CFS). Mean CFS was 26.3 ± 3.7 (median: 27; range: 2-30). Prevalence of mild (CFS: 23-19), moderate (CFS: 18-10) and severe cognitive dysfunction was 9.6% (95% confidence interval (CI): 8...
March 19, 2018: Scientific Reports
Ilona A Kaczmarek, Marek E Prost, Jaromir Wasyluk
PURPOSE: To evaluate the incidence of and factors associated with intraoperative floppy iris syndrome (IFIS) in patients undergoing cataract phacoemulsification. METHODS: In total, 319 eyes of 319 patients who underwent phacoemulsification with implantation of an intraocular lens (IOL) into the posterior chamber were included in this study. Direct injection of epinephrine into the anterior chamber was performed in all cases. The following patient information was collected: gender, age, axial length of the eye, presence of pseudoexfoliation syndrome, glaucoma, diabetes mellitus, hypertension, current use of medications including alpha1 adrenergic receptor antagonists (alpha1-ARAs), finasteride, and benzodiazepines, duration of intake of alpha1-ARAs and finasteride, and duration of the surgery...
March 17, 2018: International Ophthalmology
Ken Hayashi, Motoaki Yoshida, Tatsuhiko Sato, Shin-Ichi Manabe, Koichi Yoshimura
PURPOSE: To examine whether intraocular pressure (IOP) increases immediately after cataract surgery in eyes with pseudoexfoliation (PXF) syndrome and to assess whether orally administered acetazolamide can prevent the IOP elevation. SETTING: Hayashi Eye Hospital, Fukuoka, Japan. DESIGN: Prospective case series. METHODS: Patients with PXF syndrome scheduled for phacoemulsification were randomly assigned to 1 of 3 groups: (1) oral acetazolamide administered 1 hour preoperatively (preoperative administration group), (2) administered 3 hours postoperatively (postoperative administration group), and (3) not administered (no administration group)...
February 2018: Journal of Cataract and Refractive Surgery
Ross Lynds, Brock Hansen, Preston H Blomquist, V Vinod Mootha
PURPOSE: To examine the outcomes of resident-performed manual small-incision cataract surgery (SICS) in an urban academic setting. SETTING: Parkland Memorial Hospital, Dallas, Texas, USA. DESIGN: Retrospective case series. METHODS: Manual SICS was used only in selected cases for which phacoemulsification was expected to be difficult, namely for mature or brunescent cataracts, traumatic cataracts, and pseudoexfoliation syndrome or other causes of zonular weakness...
January 2018: Journal of Cataract and Refractive Surgery
Weng Hon Lee, Adrian Tey, Kevin Gales, Hardeep Singh Mudhar, Francisco C Figueiredo
AIM: To describe a cohort of patients with irreversible unilateral bullous keratopathy (BK) of undetermined aetiology. METHOD: Retrospective, single-centre case series in a tertiary corneal referral centre. RESULTS: Eleven consecutive patients (nine females; mean age 71.7 years) presented from 1999 to 2009 with acute onset unilateral visual loss. At presentation, the best-corrected visual acuity of the affected eyes was 6/9 or worse with mean central corneal thickness (CCT) of 684 (SD 66) μm...
February 26, 2018: British Journal of Ophthalmology
Sana' Muhsen
Purpose: Glaucoma is a progressive optic neuropathy and a leading cause of blindness. Neural losses from glaucoma are irreversible, and so the aim of glaucoma treatment is to slow progression and minimize the risk of further damage. Visual loss post filtration surgery in patients with advanced glaucomatous optic nerve damage is a rare but dreaded complication. Functional improvement is not expected. We report the case of a patient who experienced a significant loss of vision following glaucoma surgery that was followed by late visual recovery...
June 2018: American Journal of Ophthalmology Case Reports
Praveen Venkatesha Sastry, Anuj Kumar Singal
Aim. To study the outcome of cataract surgery in eyes with pseudoexfoliation without signs of glaucoma. Methods. This prospective study was done over nine months on patients with pseudoexfoliation undergoing small incision cataract surgery. Only patients with normal intraocular pressure (Central Corneal Thickness Corrected), normal cup disc ratio and open angles were included. Patients on anti-glaucoma medication were excluded. Patients underwent surgery performed by a single senior surgeon. Intraoperative and postoperative day (POD) 1 findings were noted...
July 2017: Romanian Journal of Ophthalmology
Anselm Jünemann, Robert Rejdak, Bettina Hohberger
Endothelial dysfunction and vascular dysregulation play a role in the multifactorial pathogenesis of glaucomatous optic nerve atrophy. Hyperhomocysteinemia is a risk factor for endothelial dysfunction and is associated with primary open-angle glaucoma as well as secondary open-angle glaucoma in the pseudoexfoliation syndrome. This paper reviews the literature on the association between homocysteine metabolism and glaucomatous disease and explains the possible role of hyperhomocysteinemia in the pathogenesis and progression of glaucoma...
February 2018: Klinische Monatsblätter Für Augenheilkunde
Jin Soo A Song, Jayme Vianna, Lesya Shuba, Paul Rafuse, Marcelo Nicolela
OBJECTIVE: Laser trabeculoplasty effectively reduces intraocular pressure (IOP) in primary open angle glaucoma, with argon laser trabeculoplasty (ALT) and selective laser trabeculoplasty (SLT) showing equivalent outcomes. However, it is unclear which laser modality is more effective in pseudoexfoliation (PXE) glaucoma. This study aims to compare the effectiveness of ALT and SLT in PXE glaucoma. DESIGN: Retrospective cohort study. METHODS: A chart review evaluating patients diagnosed with PXE glaucoma and treated with laser trabeculoplasty from 2005-2015...
February 2018: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
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