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pseudoexfoliation

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https://www.readbyqxmd.com/read/27898579/carotid-arterial-flow-in-pseudoexfoliation-glaucoma-and-its-role-in-diagnosing-the-disease
#1
Burcin Uz, Yasemin Durum, Tolga Kocatürk, Yelda O Dayanir, Volkan Dayanir, Mehmet Bilgen
OBJECTIVE OF THE STUDY: The objective of the study was to investigate the change in carotid arterial flow in pseudoexfoliation glaucoma (XFG) for determining its diagnostic value. MATERIALS AND METHODS: Patients with XFG (N=30) and control subjects (N=22) were recruited. Common carotid artery (CCA) and internal carotid artery of each participant were examined using color Doppler and B-mode ultrasonography. Resistivity index (RI), as a flow parameter of interest, was measured and statistically compared between the 2 groups...
December 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/27892755/association-of-single-nucleotide-polymorphisms-in-non-coding-regions-of-the-tlr4-gene-with-primary-open-angle-glaucoma-in-a-mexican-population
#2
Jose Navarro-Partida, Beatriz Alvarado Castillo, Abril Bernardette Martinez-Rizo, Ramses Rosales-Diaz, Jesus Bernardino Velazquez-Fernandez, Arturo Santos
BACKGROUND: Toll-like receptor 4 (TLR4) non-coding polymorphisms are associated to primary open angle glaucoma (POAG), normal tension glaucoma, and pseudoexfoliation glaucoma. This study was performed to determine whether non-coding single nucleotide polymorphisms (SNPs) in the TLR4 gene contribute to POAG in a Mexican population. MATERIAL AND METHODS: A total of 187 unrelated Mexican patients with POAG and 109 control subjects were included. Allelic, genotypic, and haplotypic diversity was assessed for the non-coding polymorphisms rs11536889, rs1927911, rs12377632, and rs2149356 of the TLR4 gene...
November 28, 2016: Ophthalmic Genetics
https://www.readbyqxmd.com/read/27813193/the-importance-of-and-potential-for-continuous-monitoring-of-intraocular-pressure
#3
REVIEW
Charles W McMonnies
Monitoring intraocular pressure (IOP) is a critically important part of glaucoma management; however, clinical tonometry predominantly involves sitting postures and is unable to detect variations in response to posture changes, muscular effort, deep respirations and during a wide range of activities, such as playing high wind-resistance instruments and wearing swimming goggles in addition to eye touching and rubbing. For example, the usefulness of 24-hour tonometric phasing may be increased, if nocturnal assessments included side and prone sleeping postures rather than being limited to supine posture tonometry...
November 3, 2016: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/27800269/early-postoperative-effects-of-cataract-surgery-on-anterior-segment-parameters-in-primary-open-angle-glaucoma-and-pseudoexfoliation-glaucoma
#4
Ufuk Elgin, Emine Şen, Tülay Şimşek, Kemal Tekin, Pelin Yılmazbaş
OBJECTIVES: To compare the effect of cataract surgery on anterior segment parameters measured by optical biometry in primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (PXG). MATERIALS AND METHODS: Twenty-five eyes of 25 patients with POAG and 29 eyes of 29 patients with PXG who had uncomplicated phacoemulsification and posterior chamber intraocular lens implantation surgery were included to our prospective study. Central corneal thickness (CCT), anterior chamber depth (ACD) and axial length (AL) were measured with an optical biometer preoperatively and at 1 month postoperatively...
June 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/27791246/corneal-higher-order-aberrations-after-phacoemulsification-a-comparison-of-3-different-incision-sizes
#5
Christoph von Sonnleithner, Daniel Pilger, David Homburg, Tobias Brockmann, Necip Torun, Eckart Bertelmann
PURPOSE: To analyze the impact of different incision sizes for phacoemulsification on corneal higher-order aberrations (HOA). METHODS: Patients seeking cataract surgery were randomly assigned to one of the following groups: 1.4 mm with biaxial microincision phacoemulsification (25 eyes), 1.8 mm with coaxial phacoemulsification (27 eyes), and 2.2 mm with coaxial phacoemulsification (62 eyes). Inclusion criteria were a minimum age of 18 years and uncomplicated cataract...
October 27, 2016: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/27782952/evaluation-of-the-macular-choroidal-thickness-using-spectral-optical-coherence-tomography-in-pseudoexfoliation-glaucoma
#6
Hasan A Bayhan, Seray Aslan Bayhan, İzzet Can
No abstract text is available yet for this article.
October 25, 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/27782950/mid-term-clinical-results-of-co2-laser-assisted-sclerectomy-surgery-class-for-open-angle-glaucoma-treatment
#7
Noa Geffen, Michael Mimouni, Mark Sherwood, Ehud I Assia
PURPOSE: To evaluate the efficacy and safety of CO2 Laser-assisted Sclerectomy Surgery (CLASS) in primary and pseudoexfoliative open-angle glaucoma. MATERIALS AND METHODS: Single-arm, open-label study included data from 9 medical centers located in 7 countries. Subjects underwent nonpenetrating CLASS procedure with a CO2 laser system (IOPtiMate). Intraocular pressure (IOP) and number of medications were measured at baseline, 1, 2, 4, and 6 weeks, and 3, 6, 12, 24, and 36 months...
December 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/27755351/klotho-and-endothelin-1-in-pseudoexfoliation-syndrome-and-glaucoma
#8
Mohammad H Ahoor, Amir Ghorbanihaghjo, Rana Sorkhabi, Ali Kiavar
PURPOSE: Klotho is a newly discovered protein that presumably has an important role in the aging process. The goal of this research is to compare the levels of Klotho and Endothelin-1 (ET-1) in the serum and aqueous humor of patients with pseudoexfoliation syndrome (PES) and pseudoexfoliative glaucoma (PEG). PATIENTS AND METHODS: Aqueous humor and serum samples were obtained at the time of cataract surgery from 15 patients with PES, 15 patients with PEG, and 15 control patients...
December 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/27753755/association-of-lysyl-oxidase-like-1-gene-polymorphism-in-turkish-patients-with-pseudoexfoliation-syndrome-and-pseudoexfoliation-glaucoma
#9
Mahmut Asfuroglu, Busranur Cavdarli, Ozlem G Koz, Ahmet A Yarangumeli, Emine Y Ozdemir
PURPOSE: To investigate the genetic association of lysyl oxidase-like 1 (LOXL1) gene polymorphisms in patients with pseudoexfoliation (PEX) syndrome and PEX glaucoma of Turkish descent. METHODS: Three LOXL1 single nucleotide polymorphisms (SNPs) (rs1048661, rs3825942, and rs2165241) were analyzed in 109 Turkish patients (44 patients with PEX syndrome, 65 patients with PEX glaucoma) and 47 healthy subjects. RESULTS: "A" allele of SNP rs3825942 was underrepresented in control group compared with the glaucoma [odds ratio (OR)=4...
October 6, 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/27687899/central-corneal-thickness-changes-in-bevel-up-versus-bevel-down-phacoemulsification-cataract-surgery-study-protocol-for-a-randomised-triple-blind-parallel-group-trial
#10
Soujanya Kaup, Siddharudha Shivalli, Divyalakshmi Ks, Cynthia Arunachalam, Rejitha Chinnu Varghese
INTRODUCTION: Corneal endothelial damage following phacoemulsification is still one of the major concerns of modern day cataract surgery. Although many techniques have been proposed, the risks of posterior capsular rupture and corneal endothelium damage persist. In theory, damage to the corneal endothelium is minimised by delivering the lowest phaco energy only in the direction necessary to emulsify the lens nucleus. Hence, it is believed that the bevel of the needle should be turned towards the nucleus or the nuclear fragment (ie, bevel-down...
September 29, 2016: BMJ Open
https://www.readbyqxmd.com/read/27686470/risk-factors-for-return-to-the-operating-room-after-resident-performed-cataract-surgery
#11
Shivali A Menda, Todd H Driver, Alexandra E Neiman, Seth Blumberg, Ayman Naseri, Jay M Stewart
OBJECTIVE: Investigate risk factors for unplanned return to the operating room after resident-performed cataract surgery. DESIGN: Retrospective case-control study. SETTING: Institutional. METHODS: Study population: All patients with reoperation within 90 days of resident-performed phacoemulsification were matched to four control eyes which had surgery within 30 days of the reoperation at the same institution. OBSERVATION PROCEDURE: Billing codes were used to identify all patients who underwent resident-performed intended phacoemulsification with intraocular lens placement from January 2005 to December 2010...
September 29, 2016: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/27636593/transscleral-selective-laser-trabeculoplasty-without-a-gonioscopy-lens
#12
Noa Geffen, Shay Ofir, Avner Belkin, Fani Segev, Yaniv Barkana, Audrey Kaplan Messas, Ehud I Assia, Michael Belkin
PURPOSE OF THE STUDY: The purpose of the study was to investigate results of selective laser trabeculoplasty (SLT) performed directly on the sclera without a gonioscopy lens. DESIGN: Interventional case series, prospective, randomized, masked, controlled clinical trial. METHODS: Setting: Meir Medical Center, Kfar-Saba, Israel. STUDY POPULATION: Adults with uncontrolled primary open angle or pseudoexfoliation glaucoma randomized into 2 groups...
September 15, 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/27621588/risk-factors-for-corneal-endothelial-cell-loss-by-cataract-surgery-in-eyes-with-pseudoexfoliation-syndrome
#13
Yumi Hasegawa, Ryohei Nejima, Yosai Mori, Toshihiro Sakisaka, Keiichiro Minami, Kazunori Miyata, Tetsuro Oshika
PURPOSE: The aim of this study was to investigate the factors associated with decreases in corneal endothelial cell density (ECD) resulting from cataract surgery in eyes with pseudoexfoliation syndrome (PEX). METHODS: The clinical records of 78 eyes of 78 patients with PEX who had undergone cataract surgery were reviewed. ECD was measured preoperatively and at 3 months postoperatively with specular microscopy. Multiple regression analysis was used to assess the factors that were significantly related to the rate of ECD loss...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27599212/evaluation-of-vitrectomy-and-reimplantation-following-late-dislocation-of-the-intraocular-lens-capsular-bag-complex-a-3-years-follow-up-study
#14
Manuel F Bande, Irina García-Garcés, Laura Paniagua, Francisco Ruiz-Oliva, Antonio Piñeiro, Maria Jose Blanco-Teijeiro
OBJECTIVES: To study the predisposition factors for dislocation of the intraocular lens (IOL)-capsular bag complex and analyze the results of subsequent reimplantation surgery. METHODS: The exclusion criteria were complicated cataract surgery and minor dislocations that appeared in the first year after cataract surgery. Thirty-six months of monitoring of the reimplantation surgery was required. The primary measurements of results were factors concerning dislocation, the interval between cataract surgery and dislocation, and postoperative complications...
September 2, 2016: Retina
https://www.readbyqxmd.com/read/27599175/patterns-of-retinal-nerve-fiber-layer-loss-in-different-subtypes-of-open-angle-glaucoma-using-spectral-domain-optical-coherence-tomography
#15
Neda Baniasadi, Eleftherios I Paschalis, Mahdi Haghzadeh, Pallavi Ojha, Tobias Elze, Mufeed Mahd, Teresa C Chen
PURPOSE OF THE STUDY: The purpose of the study was to determine whether there are different patterns of retinal nerve fiber layer (RNFL) thinning as measured by spectral domain optical coherence tomography (SD-OCT) for 4 subtypes of open angle glaucoma (OAG): primary OAG (POAG), normal tension glaucoma (NTG), pseudoexfoliation glaucoma (PXG), and pigmentary glaucoma (PDG) and to compare them with normal controls. MATERIALS AND METHODS: SD-OCT RNFL thickness values were measured for 4 quadrants and for 4 sectors (ie, superior-nasal, superior-temporal, inferior-nasal, and inferior-temporal)...
October 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/27588268/nitric-oxide-and-tumour-necrosis-factor-alpha-in-the-process-of-pseudoexfoliation-glaucoma
#16
Tatjana S Sarenac Vulovic, Sladjana M Pavlovic, Vladimir Lj Jakovljevic, Katarina B Janicijevic, Nemanja S Zdravkovic
AIM: To establish the role of nitric oxide (NO), ascorbic acid and tumour necrosis factor-α (TNF-α) in the pathogenesis of pseudoexfoliation glaucoma (XFG). METHODS: Our study included 120 patients who were referred for cataract surgery. All patients were divided into four groups according to clinical findings: XFG, early and late pseudoexfoliation syndrome (XFS), and cataract (without pseudoexfoliation). Serum and aqueous humour levels of the ascorbic acid, NO and TNF-α were measured...
2016: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/27588267/optic-disc-area-in-different-types-of-glaucoma
#17
Oya Tekeli, Esra Savku, Ahmed Abdullayev
AIM: To evaluate the possible relationship of optic disc area with retina nerve fiber layer in different glaucoma subtypes. METHODS: One eye each was chosen from 45 patients with ocular hypertension, 45 patients with primary open angle glaucoma, 45 patients with pseudoexfoliation glaucoma and 45 healthy controls followed in our hospital. The records of the patients were reviewed retrospectively. Optic disc area and circumpapillary retina nerve fiber layer measurements were obtained using optical coherence tomography...
2016: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/27580950/central-corneal-thickness-in-newly-diagnosed-glaucoma-patients-in-south-west-ethiopia-a-cross-sectional-study
#18
Kumale Tolesa, Girum W Gessesse
BACKGROUND: Reports of central corneal thickness (CCT) among glaucoma patients, particularly for pseudoexfoliative glaucoma (PXG) and Primary Angle Closure Glaucoma (PACG) are scarce in the Sub-Saharan African (SSA) population. The aim of this study is to evaluate CCT in black patients with newly diagnosed glaucoma and ocular hypertension (OHT) in South West Ethiopia. METHODS: This was a prospective study undertaken with an ultrasonic pachymeter from June 2014 to February 2015 in Jimma University Specialized Hospital...
2016: BMC Ophthalmology
https://www.readbyqxmd.com/read/27569700/intraocular-lens-dislocation-in-pseudoexfoliation-a-systematic-review-and-meta-analysis
#19
Pedro Vazquez-Ferreiro, Francisco J Carrera-Hueso, Narjis Fikri-Benbrahim, Lidia Barreiro-Rodriguez, Marta Diaz-Rey, María Auxiliadora Ramón Barrios
PURPOSE: To evaluate the impact of pseudoexfoliation syndrome on intraocular lens (IOL) dislocation after phacoemulsification cataract surgery and explore possible associations related to surgical technique. METHODS: We systematically searched the MEDLINE, Embase, Web of Science, Cochrane, and Lilacs databases and grey literature sources and identified (on March 1, 2016) 14 cohort and case-control studies comparing IOL dislocation in patients with and without pseudoexfoliation syndrome who had undergone phacoemulsification...
August 29, 2016: Acta Ophthalmologica
https://www.readbyqxmd.com/read/27552510/scanning-electron-microscopy-evaluation-of-an-ex-press-mini-glaucoma-shunt-after-explantation
#20
Daniele Tognetto, Paolo Cecchini, Rossella D'Aloisio, Odilla Vattovani, Gianluca Turco
We report a case of an explanted stainless steel miniature glaucoma drainage device (EX-PRESS) implanted under a scleral flap for pseudoexfoliation open-angle glaucoma surgical treatment. The glaucoma shunt was implanted in a 75-year-old white man with medically refractive glaucoma. Cataract surgery was performed simultaneously. After 2 years, the shunt extruded through the scleral flap and the conjunctiva and it was, therefore, explanted. Scanning electron microscopy images of the EX-PRESS mini glaucoma shunt were acquired to verify the patency of the device lumen and the presence of fibrosis or cellular adhesion on the device...
August 22, 2016: Journal of Glaucoma
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