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https://www.readbyqxmd.com/read/28815099/enabling-comprehension-of-patient-subgroups-and-characteristics-in-large-bipartite-networks-implications-for-precision-medicine
#1
Suresh K Bhavnani, Tianlong Chen, Archana Ayyaswamy, Shyam Visweswaran, Gowtham Bellala, Divekar Rohit, Bassler Kevin E
A primary goal of precision medicine is to identify patient subgroups based on their characteristics (e.g., comorbidities or genes) with the goal of designing more targeted interventions. While network visualization methods such as Fruchterman-Reingold have been used to successfully identify such patient subgroups in small to medium sized data sets, they often fail to reveal comprehensible visual patterns in large and dense networks despite having significant clustering. We therefore developed an algorithm called ExplodeLayout, which exploits the existence of significant clusters in bipartite networks to automatically "explode" a traditional network layout with the goal of separating overlapping clusters, while at the same time preserving key network topological properties that are critical for the comprehension of patient subgroups...
2017: AMIA Summits on Translational Science Proceedings
https://www.readbyqxmd.com/read/28811042/understanding-readmissions-in-children-undergoing-surgery-a-pediatric-nsqip-analysis
#2
Afif N Kulaylat, Dorothy V Rocourt, Anthony Y Tsai, Kathryn L Martin, Brett W Engbrecht, Mary C Santos, Robert E Cilley, Christopher S Hollenbeak, Peter W Dillon
BACKGROUND: Readmission is increasingly being utilized as an important clinical outcome and measure of hospital quality. Our aim was to delineate rates, risk factors, and reasons for unplanned readmission in pediatric surgery. MATERIALS AND METHODS: Retrospective review of pediatric patients (n=130,274) undergoing surgery (2013-2014) at hospitals enrolled in the Pediatric National Surgical Quality Improvement Program (NSQIP-P) was performed. Logistic regression was used to model factors associated with unplanned 30-day readmission...
July 31, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28807692/community-use-of-physical-and-occupational-therapy-after-stroke-and-risk-of-hospital-readmission
#3
Janet K Freburger, Dongmei Li, Erin P Fraher
OBJECTIVES: To determine whether receipt of therapy and number and timing of therapy visits decreased hospital readmission risk in stroke survivors discharged home. DESIGN: Retrospective cohort analysis of Medicare claims (2010-2013). SETTING: Acute care hospital and community. PARTICIPANTS: Patients hospitalized for stroke who were discharged home and survived the first 30 days (N=23,413; mean [SD] age of 77.6 [7.5] years)...
August 11, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28805175/outcomes-of-a-psycho-education-and-monitoring-programme-to-prevent-compulsory-admission-to-psychiatric-inpatient-care-a-randomised-controlled-trial
#4
B Lay, W Kawohl, W Rössler
BACKGROUND: There is a need for interventions that effectively reduce compulsory admission to psychiatry. We conducted a randomised controlled trial to investigate whether an innovative intervention programme prevents compulsory re-admission in people with serious mental illness. METHODS: The programme addresses primarily patients' self-management skills. It consists of individualised psychoeducation focusing on behaviours prior to and during illness-related crises, crisis cards and, after discharge from the psychiatric hospital, a 24-month preventive monitoring...
August 14, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28802542/the-impact-of-intravenous-alteplase-on-long-term-patient-survival-the-georgia-coverdell-acute-stroke-registry-s-experience
#5
Moges S Ido, Michael R Frankel, Ike S Okosun, Richard B Rothenberg
INTRODUCTION: Intravenous alteplase reduces disability and improves functionality among acute ischemic stroke patients. Two decades after its approval, only a small fraction of patients get the treatment, and demonstrating its impact on mortality may make a strong case for its wider use. This study assessed the impact of thrombolytic treatment by alteplase on 1-year mortality and readmission among acute ischemic stroke patients. METHOD: The 2008-2013 Georgia Coverdell Acute Stroke Registry data were linked with the 2008-2013 hospital discharge and the 2008-2014 death data in Georgia...
July 31, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28801217/evaluation-of-unplanned-hospital-readmissions-after-major-urologic-inpatient-surgery-in-the-era-of-accountable-care
#6
Benjamin V Stone, Matthew R Cohn, Nicholas M Donin, Michael Schulster, James S Wysock, Danil V Makarov, Marc A Bjurlin
OBJECTIVE: To provide a multi-institutional analysis of clinical factors predicting unplanned hospital readmission after major inpatient urologic surgery. MATERIALS AND METHODS: The American College of Surgeons National Surgical Quality Improvement Program (NSQIP) is a risk-adjusted data collection mechanism for analyzing clinical outcomes data including 30-day perioperative readmissions and complications. We identified 23,108 patients who underwent major inpatient urologic surgery from 2011 to 2012...
August 8, 2017: Urology
https://www.readbyqxmd.com/read/28801110/risk-factors-for-30-day-readmission-in-patients-with-congestive-heart-failure
#7
Katelin A Mirkin, Laura M Enomoto, Gregory M Caputo, Christopher S Hollenbeak
BACKGROUND: Risk of readmission is elevated in patients congestive heart failure (CHF), and clinical decision makers need to better understand risk factors for 30-day readmissions. OBJECTIVE: To identify risk factors for readmission in patients with CHF. METHODS: We studied all admissions for patients with CHF during 2011 using a statewide discharge data set from Pennsylvania. The primary outcome was readmission to any Pennsylvania hospital within 30 days of discharge...
August 8, 2017: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/28800719/total-ankle-arthroplasty-comparing-perioperative-outcomes-when-performed-at-an-orthopaedic-specialty-hospital-versus-an-academic-teaching-hospital
#8
David M Beck, Eric M Padegimas, David I Pedowitz, Steven M Raikin
BACKGROUND: The number of total ankle arthroplasties (TAAs) performed in the United States has risen significantly in recent years, as has utilization of orthopaedic specialty hospital (OSH) to treat healthy patients undergoing elective surgery. The purpose of this study was to compare postoperative outcomes following TAA at an OSH when compared with a matching population of patients undergoing TAA at an academic teaching hospital (ATH). METHODS: We identified all TAA from January 2014 to December 2014 at the OSH and January 2010 to January 2016 at the ATH...
August 1, 2017: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/28792149/short-term-outcomes-of-laparoscopic-greater-curvature-plication-and-laparoscopic-sleeve-gastrectomy-in-patients-with-a-body-mass-index-of-30-to-35-kg-m%C3%A2
#9
Yeon Ho Park, Seong Min Kim
PURPOSE: The aim of this study was the compare the midterm outcomes of laparoscopic greater curvature plication (LGCP) and laparoscopic sleeve gastrectomy (LSG) in obese patients with a body mass index (BMI) of 30 to 35 kg/m². MATERIALS AND METHODS: This single center, retrospective review of prospectively collected data was conducted for obese patients that underwent LGCP or LSG from March 2013 to February 2016. These two patient groups were compared in terms of demographics, perioperative outcomes, weight loss [percent excess weight loss (%EWL)], comorbidity resolution, and immediate and long-term complications...
September 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/28789801/early-ambulation-after-grafting-of-lower-extremity-burns
#10
J P Gawaziuk, B Peters, S Logsetty
OBJECTIVE: Early ambulation of lower extremity burns that undergo a skin graft may help to avoid some of the complications associated with immobilization. Despite recent evidence supporting early ambulation, post-operative immobilization following lower extremity skin grafting is still a common practice. The purpose of this study was to retrospectively assess the outcomes of lower extremity skin graft cases dressed with a multi-layer compression bandage who were ambulated in the immediate post-operative period...
August 5, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28782104/emergency-department-visits-hospitalizations-and-readmissions-of-patients-with-a-peritonsillar-abscess
#11
Romaine F Johnson
OBJECTIVES: To determine the demographics and treatment outcomes of patients with a peritonsillar abscess (PTA) and to provide guidance for treatment options. METHODS: The 2012 National Emergency Department Database, 2012 National Inpatient Sample, and 2013 Nationwide Readmissions Database were used to analyze patients with a PTA who presented to emergency departments (ED), were admitted and/or readmitted to hospitals in the United States. Outcomes were used to create a decision model to compare initial medical versus surgical management...
August 7, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28772083/pilot-study-of-a-palliative-care-and-medical-oncology-co-rounding-model-for-advanced-cancer-inpatients-in-a-tertiary-hospital-in-singapore
#12
Grace Meijuan Yang, Ravindran Kanesvaran, Shirlyn Hui-Shan Neo, Alethea Chung Pheng Yee, Susan Dale Block, Yin Bun Cheung
OBJECTIVE: Our aim was to obtain initial estimates of the effect of a palliative care and medical oncology co-rounding model on hospital length of stay, proportion of patients reviewed by specialist palliative care (SPC), and proportion of patients who were readmitted within 7 and 30 days of hospital discharge. BACKGROUND: Earlier timing of palliative care improves patient outcomes, but current consultative models of palliative care service delivery are not feasible for widespread implementation...
August 3, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28771405/pediatric-readmissions-after-hospitalizations-for-lower-respiratory-infections
#13
Mari M Nakamura, Alan M Zaslavsky, Sara L Toomey, Carter R Petty, Maria C Bryant, Alexandra T Geanacopoulos, Ashish K Jha, Mark A Schuster
BACKGROUND AND OBJECTIVE: Lower respiratory infections (LRIs) are among the most common reasons for pediatric hospitalization and among the diagnoses with the highest number of readmissions. Characterizing LRI readmissions would help guide efforts to prevent them. We assessed variation in pediatric LRI readmission rates, risk factors for readmission, and readmission diagnoses. METHODS: We analyzed 2008-2009 Medicaid Analytic eXtract data for patients <18 years of age in 26 states...
August 2017: Pediatrics
https://www.readbyqxmd.com/read/28770132/congenital-duodenal-obstruction-situs-inversus-totalis-and-gastric-perforation-in-a-neonate
#14
Rajat Piplani, Samir K Acharya, Deepak Bagga
We report a rare case of incomplete congenital duodenal obstruction (Type 1 duodenal atresia) in association with situs inversus totalis presenting with gastric perforation in a neonate. The infantogram was suggestive of perforation with air under diaphragm along with dextrocardia. On exploration, a pin point perforation at fundus near lesser curvature along with situs inversus was noted. Primary closure of gastric perforation was done. Patient was then discharged on full breast feeds but was readmitted with intolerance to feeds and recurrent bilious vomiting...
April 2017: Journal of Neonatal Surgery
https://www.readbyqxmd.com/read/28768329/national-readmission-patterns-of-isolated-splenic-injuries-based-on-initial-management-strategy
#15
Graeme M Rosenberg, Lisa Knowlton, Charlotte Rajasingh, Yingie Weng, Paul M Maggio, David A Spain, Kristan L Staudenmayer
Importance: Options for managing splenic injuries have evolved with a focus on nonoperative management. Long-term outcomes, such as readmissions and delayed splenectomy rate, are not well understood. Objective: To describe the natural history of isolated splenic injuries in the United States and determine whether patterns of readmission were influenced by management strategy. Design, Setting, and Participants: The Healthcare Cost and Utilization Project's Nationwide Readmission Database is an all-payer, all-ages, longitudinal administrative database that provides data on more than 35 million weighted US discharges yearly...
August 2, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28768254/intracorporeal-versus-extracorporeal-anastomoses-following-laparoscopic-right-colectomy-in-obese-patients-a-case-matched-study
#16
Andrea Vignali, Ugo Elmore, Maria Lemma, Giovanni Guarnieri, Giovanni Radaelli, Riccardo Rosati
BACKGROUND/AIMS: To compare short- and long-term outcomes of intracorporeal anastomosis (IA) versus extracorporeal anastomosis (EA) in obese (body mass index >30 kg/m2) patients. PATIENTS AND METHODS: Sixty-four consecutive obese patients who underwent laparoscopic (LPS) right colectomy with IA were matched with 64 patients who underwent LPS right colectomy with EA. Intraoperative variables, short-term outcomes, readmission rates, and morbidity and mortality rates were analyzed along with long-term outcomes...
August 3, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28760355/decreasing-readmissions-by-focusing-on-complications-and-underlying-reasons
#17
Cigdem Benlice, Dilara Seyidova-Khoshknabi, Luca Stocchi, Tracy Hull, Scott Steele, Emre Gorgun
BACKGROUND: To analyze demographics and outcomes of patients focusing on 30-day readmission status and identify procedure-specific risk factors. METHODS: Patients undergoing abdominal colorectal surgery (2011-2013) were identified Demographics and outcomes including in-hospital complications were compared based on readmission status. RESULTS: A total of 6637 patients were identified with a mean age of 51.2(±17.1) years. Seven hundred and seventy five(11...
July 21, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28759896/an-analysis-of-diagnoses-that-drive-readmission-what-can-we-learn-from-the-hospitals-in-southern-new-england-with-the-highest-and-lowest-readmission-performance
#18
Blake Morphis, Rouba Youssef, Rebekah Gardner, Elizabeth M Goldberg
T Background: The Hospital Readmission Reduction Program was instituted by the Centers for Medicare & Medicaid Services in 2012 to incentivize hospitals to reduce readmissions. OBJECTIVE: To examine the most common diagnoses driving readmissions among fee-for-service Medicare beneficiaries in the hospitals with the highest and lowest readmission performance in Southern New England from 2014 to 2016. METHODS: This is a retrospective observational study using publicly available Hospital Compare data and Medicare Part A claims data...
August 1, 2017: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/28753813/hospital-readmissions-after-urological-surgical-procedures-in-france-a-nationwide-cohort-study-over-3-years
#19
Quentin Manach, Morgan Rouprêt, Jeanne Reboul-Marty, Sarah J Drouin, Cyrille Guillot-Tantay, Xavier Matillon, Jérome Parra, Pierre Mozer, Marc-Oliver Bitker, Jérémie H Lefèvre, Véronique Phé
BACKGROUND: Identifying the predictive factors for hospital readmission is required to target preventive measures. OBJECTIVE: To assess the rate of surgical readmissions after a urological procedure and the risk factors associated with readmission. DESIGN, SETTING, AND PARTICIPANTS: Data from all hospitalizations between January 2010 and November 2012 in France, regarding planned urological surgeries, were retrieved from the national medical database...
June 16, 2017: European Urology Focus
https://www.readbyqxmd.com/read/28753778/the-fate-of-radical-cystectomy-patients-after-hospital-discharge-understanding-the-black-box-of-the-pre-readmission-interval
#20
Naveen Krishnan, Benjamin Li, Bruce L Jacobs, Sapan N Ambani, Tudor Borza, Chang He, Brent K Hollenbeck, Todd Morgan, Khaled S Hafez, Alon Z Weizer, Jeffrey S Montgomery, Cheryl T Lee, Opal Lesse, Mariel S Lavieri, Jonathan E Helm, Ted A Skolarus
BACKGROUND: Radical cystectomy has one of the highest 30-d hospital readmission rates but circumstances leading to readmission remain poorly understood. OBJECTIVE: To examine the postdischarge period and better understand hospital readmission after radical cystectomy. DESIGN, SETTING, AND PARTICIPANTS: We conducted a retrospective cohort study of patients treated with radical cystectomy for bladder cancer from 2005 to 2012 using our institutional database...
August 4, 2016: European Urology Focus
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