Nuvigil

No abstract text is available yet for this article.

No abstract text is available yet for this article.

OBJECTIVE: West Nile Virus (WNV) may evolve into West Nile Encephalitis (WNE) in older individuals. Most of these WNE seniors do not survive. The long-term outcome profiles of those who do survive WNE have not been well studied. This poster will serve as a follow-up to a 2014 INS poster presentation poster of a 74 year-old Caucasian male who was recovering from WNE. Medicare reimburses time-limited rehabilitation services, and many of this individual's lower-level functions were rehabilitated via several months of inpatient and outpatient rehabilitation...

Modafinil, in its two clinical formulations (Provigil(®) and Nuvigil(®)), is a widely prescribed wake-promoting therapeutic agent. It binds competitively to the cell-membrane dopamine (DA) transporter and is dependent on catecholaminergic (dopaminergic and adrenergic) signaling for its wake-promoting effects. The clinical spectrum of effects for modafinil is distinct from the effects seen with other catecholaminergic agents. Relative to other commonly used agents that act through catecholaminergic mechanisms, modafinil has a relatively low abuse potential, produces wakefulness with an attenuated compensatory sleep recovery thereafter, and does not ameliorate cataplexy in narcolepsy...

BACKGROUND: Armodafinil (Nuvigil(®), Cephalon, Inc., Frazer, PA, USA), the longer-lasting isomer of racemic modafinil, is a nonamphetamine, wakefulness-promoting medication. In patients with excessive sleepiness associated with shift work disorder, treated obstructive sleep apnoea, or narcolepsy, armodafinil has been found to improve wakefulness throughout the shift or day. In addition, while not approved for this indication, armodafinil has been found to improve excessive sleepiness associated with jet-lag disorder...

No abstract text is available yet for this article.

No abstract text is available yet for this article.