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https://www.readbyqxmd.com/read/29886211/has-anatomic-complexity-of-abdominal-aortic-aneurysms-undergoing-open-surgical-repair-changed-after-the-introduction-of-endovascular-treatment-systematic-review-and-metanalysis-of-comparative-studies
#1
REVIEW
Nikolaos Kontopodis, Emmanouil Tavlas, Efstratios Georgakarakos, Nikolaos Galanakis, Christos Chronis, Dimitrios Tsetis, Christos V Ioannou
PURPOSE: At a time when endovascular aneurysm repair (EVAR) is increasingly used to treat abdominal aortic aneurysms (AAAs), lesions undergoing open surgical repair (OSR) may present significant differences compared to those treated before wide EVAR availability. We aim to record discrepancies in AAAs surgically treated before and after the introduction of EVAR. METHODS: We conducted a systematic review of the literature and meta-analysis of comparative studies...
June 7, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29803894/impact-of-selective-serotonin-reuptake-inhibitors-ssris-during-pregnancy-and-lactation-a-focus-on-short-and-long-term-vascular-effects
#2
REVIEW
S Zullino, T Simoncini
SSRIs are the first choice for the treatment of mood disorders during pregnancy and lactation. Despite the known side effects, the benefits/risks balance suggests their use. Hypertensive disorders of pregnancy (HDP) and Intrauterine growth restriction (IUGR) are the main vascular effects of these drugs, with mechanisms that involves endothelial dysfunction in feto-placental system. These data are supported by animal models, even if preliminary findings are not yet adequately supported by molecular and clinical data...
May 24, 2018: Vascular Pharmacology
https://www.readbyqxmd.com/read/29777162/hiv-and-vertebral-fractures-a-systematic-review-and-metanalysis
#3
Thales A S H Ilha, Fabio V Comim, Rafaela M Copes, Juliet E Compston, Melissa O Premaor
The survival of HIV-infected patients has increased with the advent of antiretroviral therapy with the emergence of new comorbidities. Vertebral fracture is a manifestation of reduced bone strength and osteoporosis. This study aims to assess the frequency of spine fractures in HIV-positive men and women aged over 18 years. We performed a systematic review of randomized controlled trials, cohort studies, cross-sectional studies, and case-control studies. Studies that evaluated morphometric and/or clinical vertebral fracture were included...
May 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29699781/long-term-follow-up-for-pilonidal-sinus-surgery-a-review-of-literature-with-metanalysis
#4
REVIEW
M Milone, N Velotti, M Manigrasso, P Anoldo, F Milone, G D De Palma
BACKGROUND: Sacrococcygeal pilonidal sinus disease (PSD) is a common chronic inflammation of the natal cleft and presents as an abscess or a chronically discharging, painful sinus tract. The management of chronic PSD is variable, contentious, and problematic. Although many surgical procedures have been tried, the best surgical method remains controversial. The aim of this systematic review with meta-analysis of literature is to provide surgeons an objective instrument of decision through an analysis of recurrence rate of various surgical techniques in a long-term follow-up...
April 23, 2018: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/29602980/placenta-previa-and-placental-abruption-after-assisted-reproductive-technology-in-patients-with-endometriosis-a-systematic-review-and-meta-analysis
#5
Maria Luisa Gasparri, Konstantinos Nirgianakis, Katayoun Taghavi, Andrea Papadia, Michael D Mueller
INTRODUCTION: Recent evidence suggests that assisted reproductive technology (ART) increases the risk of adverse pregnancy outcomes, including placental disorders. Similarly, endometriosis resulted detrimental on placenta previa. However, up to 50% of women with endometriosis suffer from infertility, thus requiring ART. The aim of our metanalysis is to compare women with and without endometriosis undergoing ART in terms of placenta disorders events, to establish if ART itself or endometriosis, as an indication to ART, increases the risk of placenta previa...
March 30, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29367542/insights-from-second-line-treatments-for-idiopathic-dilated-cardiomyopathy
#6
Marco Luciani, Federica Del Monte
BACKGROUND: Dilated cardiomyopathy (DCM) is an independent nosographic entity characterized by left ventricular dilatation and contractile dysfunction leading to heart failure (HF). The idiopathic form of DCM (iDCM) occurs in the absence of coronaropathy or other known causes of DCM. Despite being different from other forms of HF for demographic, clinical, and prognostic features, its current pharmacological treatment does not significantly diverge. METHODS: In this study we performed a Pubmed library search for placebo-controlled clinical investigations and a post-hoc analysis recruiting iDCM from 1985 to 2016...
August 23, 2017: Journal of Cardiovascular Development and Disease
https://www.readbyqxmd.com/read/29241844/efficacy-and-safety-of-routine-aspiration-thrombectomy-during-primary-pci-for-st-segment-elevation-myocardial-infarction-a-meta-analysis-of-large-randomized-controlled-trials
#7
Konstantinos Marmagkiolis, Abdul Hakeem, Mehmet Cilingiroglu, Dmitriy N Feldman, Konstantinos Charitakis
BACKGROUND: Recent randomized controlled trials (RCTs) have questioned the clinical efficacy and safety of routine aspiration thrombectomy (AT) during primary percutaneous coronary intervention (PCI). A systematic synthesis of these randomized data is hence very timely to address this clinical equipoise. METHODS: We performed a meta-analysis of the larger (>150 patients) RCTs that compared AT with only primary PCI. Procedural endpoints were myocardial blush grade (MBG) score of 0 or 1 and ST-segment resolution (STR) >50%...
December 12, 2017: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/29241310/indocyanine-green-fluorescence-guided-sentinel-lymph-node-identification-in-urologic-cancers-a-systematic-review-and-meta-analysis
#8
Fouad Aoun, Simone Albisinni, Marc Zanaty, Toufic Hassan, Gunter Janetschek, Roland van Velthoven
INTRODUCTION: To date, bilateral pelvic lymph node dissection (PLND) represents the most accurate and reliable staging procedure for the detection of lymph node invasion in prostate cancer and bladder cancer. However, the procedure is not devoid of complications. In this field, Indocyanine green fluorescence-guided sentinel lymph node (SLN) identification is an emerging and promising technique, as accurate staging of urologic cancer could be enhanced by a thorough evaluation of the sentinel lymph nodes...
December 14, 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/29205995/volume-and-health-outcomes-evidence-from-systematic-reviews-and-from-evaluation-of-italian-hospital-data
#9
Laura Amato, Danilo Fusco, Anna Acampora, Katia Bontempi, Alessandro Cesare Rosa, Paola Colais, Fabio Cruciani, Mariangela D'Ovidio, Francesca Mataloni, Silvia Minozzi, Zuzana Mitrova, Luigi Pinnarelli, Rosella Saulle, Salvatore Soldati, Chiara Sorge, Simona Vecchi, Martina Ventura, Marina Davoli
BACKGROUND Improving quality and effectiveness of healthcare is one of the priorities of health policies. Hospital or physician volume represents a measurable variable with an impact on effectiveness of healthcare. An Italian law calls for the definition of «qualitative, structural, technological, and quantitative standards of hospital care». There is a need for an evaluation of the available scientific evidence in order to identify qualitative, structural, technological, and quantitative standards of hospital care, including the volume of care above or below which the public and private hospitals may be accredited (or not) to provide specific healthcare interventions...
September 2017: Epidemiologia e Prevenzione
https://www.readbyqxmd.com/read/29090356/ilm-peeling-in-nontractional-diabetic-macular-edema-review-and-metanalysis
#10
REVIEW
M Rinaldi, R dell'Omo, F Morescalchi, F Semeraro, E Gambicorti, F Cacciatore, F Chiosi, C Costagliola
PURPOSE: To evaluate the effect of internal limiting membrane (ILM) peeling during vitrectomy for nontractional diabetic macular edema. METHODS: PUBMED, MEDLINE and CENTRAL were reviewed using the following terms (or combination of terms): diabetic macular edema, nontractional diabetic macular edema, internal limiting membrane peeling, vitrectomy, Müller cells. Randomized and nonrandomized studies were included. The eligible studies compared anatomical and functional outcomes of vitrectomy with or without ILM peeling for tractional and nontractional diabetic macular edema...
October 31, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28967439/new-evidence-in-one-lung-ventilation
#11
H Meleiro, I Correia, P Charco Mora
Mechanical ventilation in thoracic surgery has undergone significant changes in recent years due to the implementation of the protective ventilation. This review will analyze recent ventilatory strategies in one-lung ventilation. A MEDLINE research was performed using Mesh term "One-Lung Ventilation" including randomized clinical trials, metanalysis, reviews and systematic reviews published in the last 6 years. Search was performed on 21st March 2017. A total of 75 articles were initially found. After title and abstract review 14 articles were included...
March 2018: Revista Española de Anestesiología y Reanimación
https://www.readbyqxmd.com/read/28671281/water-status-and-must-composition-in-grapevine-cv-chardonnay-with-different-soils-and-topography-and-a-mini-meta-analysis-of-the-%C3%AE-13-c-water-potentials-correlation
#12
Luca Brillante, Olivier Mathieu, Jean Lévêque, Cornelis van Leeuwen, Benjamin Bois
BACKGROUND: The measurement of carbon isotopic discrimination in grape sugars at harvest (δ13 C) is an integrated assessment of water status during ripening. It is an efficient alternative to assess variability in the field and discriminate between management zones in precision viticulture, but further work is needed to completely understand the signal. RESULTS: This work, spanning over 3 years, performed in a hillslope toposequence in Burgundy, delineates the relationships between main soil properties (gravel amount, slope, texture) and the grapevine water status assessed by δ13 C...
January 2018: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28379923/serum-markers-of-necrotizing-enterocolitis-a-systematic-review
#13
Gianluca Terrin, Laura Stronati, Salvatore Cucchiara, Mario De Curtis
OBJECTIVE: The aim of the study was to systematically review the diagnostic utility of serum biomarkers for the diagnosis of necrotizing enterocolitis (NEC). METHODS: We conducted an electronic and manual search of the available evidence. We included studies reporting data on the diagnostic accuracy of "serum" biomarkers for the diagnosis of NEC, available until January 2016. RESULTS: We selected 22 studies from the 1296 articles retrieved...
December 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27971814/a-network-metanalysis-to-compare-biologic-agents-in-the-treatment-of-non-radiographic-axial-spondyloarthritis
#14
A Migliore
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27908252/the-combination-of-new-immunotherapy-and-radiotherapy-a-n-ew-potential-treatment-for-locally-advanced-non-small-cell-lung-cancer
#15
REVIEW
Paola C Sacco, Paolo Maione, Cesare Guida, Cesare Gridelli
Lung cancer is the main reason of cancer death worldwide. About 30% of non-small-cell lung cancer (NSCLC) cases are diagnosed with locally advanced disease (stage III). This is a mixed population including patients who have far more extensive and bulky disease than others. Management of these patients continue to be a challenge; frequently, patients have both local recurrence and distant metastases in this stage and the prognosis is very poor with a 5-year overall survival estimated between 3% and 7% for inoperable disease...
2017: Current Clinical Pharmacology
https://www.readbyqxmd.com/read/27859830/fast-evaluation-and-monitoring-of-ingenol-mebutate-treatment-of-multiple-basal-cell-carcinomas-by-in-vivo-hand-held-reflectance-confocal-microscopy
#16
LETTER
E Manubens, A Barreiro, A Bennassar, S Podlipnik, N Moreno, P Iglesias, J Malvehy, S Puig
No abstract text is available yet for this article.
November 11, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27733159/moderate-intensity-statin-therapy-seems-ineffective-in-primary-cardiovascular-prevention-in-patients-with-type-2-diabetes-complicated-by-nephropathy-a-multicenter-prospective-8-years-follow-up-study
#17
MULTICENTER STUDY
Ferdinando Carlo Sasso, Nadia Lascar, Antonella Ascione, Ornella Carbonara, Luca De Nicola, Roberto Minutolo, Teresa Salvatore, Maria Rosaria Rizzo, Plinio Cirillo, Giuseppe Paolisso, Raffaele Marfella
BACKGROUND: Although numerous studies and metanalysis have shown the beneficial effect of statin therapy in CVD secondary prevention, there is still controversy such the use of statins for primary CVD prevention in patients with DM. The purpose of this study was to evaluate the occurrence of total major adverse cardio-vascular events (MACE) in a cohort of patients with type 2 diabetes complicated by nephropathy treated with statins, in order to verify real life effect of statin on CVD primary prevention...
October 13, 2016: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/27496262/amiodarone-or-lidocaine-for-cardiac-arrest-a-systematic-review-and-meta-analysis
#18
REVIEW
F Sanfilippo, C Corredor, C Santonocito, G Panarello, A Arcadipane, G Ristagno, T Pellis
BACKGROUND: Guidelines for treatment of out-of-hospital cardiac arrest (OOH-CA) with shockable rhythm recommend amiodarone, while lidocaine may be used if amiodarone is not available. Recent underpowered evidence suggests that amiodarone, lidocaine or placebo are equivalent with respect to survival at hospital discharge, but amiodarone and lidocaine showed higher hospital admission rates. We undertook a systematic review and meta-analysis to assess efficacy of amiodarone vs lidocaine vs placebo...
October 2016: Resuscitation
https://www.readbyqxmd.com/read/27404944/clinical-features-and-complications-of-the-hla-b27-associated-acute-anterior-uveitis-a-metanalysis
#19
REVIEW
Enzo Maria D'Ambrosio, Maurizio La Cava, Paolo Tortorella, Magda Gharbiya, Michelangelo Campanella, Ludovico Iannetti
In this article, we report a literature-based metanalysis we have conducted to outline the clinical features of the HLA-B27 Acute Anterior Uveitis (AAU). The examined material was based on observational studies in which participants were affected by Acute Anterior Uveitis and divided into HLA B27+ and HLA B27-. We performed a search on articles with the words "HLA B27 uveitis" dated before May 2014. Among these, 29 articles were selected for a second review. After a further evaluation, 22 articles were analyzed...
2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/27374048/cardiac-rehabilitation-is-safe-and-effective-also-in-the-elderly-but-don-t-forget-about-drugs
#20
Donatella Del Sindaco, Maria Denitza Tinti, Giovanni Pulignano, Stefano Tolone, Giovanni Minardi, Massimo Uguccioni, Antonio Lax
In the setting of heart failure (HF) pharmacotherapy demonstrates a quantifiable improvement in exercise tolerance also in HF with preserved ejection fraction (HFpEF). For patients with HFpEF, often older, with higher prevalence of hypertension, diabetes mellitus, atrial fibrillation and other comorbidities, endpoints such as quality of life and functional capacity may be more clinically relevant. However several study show as the use of ACE-I and B-blocker were lesser than expected. Beta-blocker therapy is the keystone of pharmacotherapy of HF patients and exercise training is the essential core of rehabilitation programs, it is important to elucidate the relationship between these therapies...
June 22, 2016: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
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