Özlem Özdemir, Baha Zengel, Yaşar Yildiz, Basak Oyan Uluç, Devrim Cabuk, Ercan Ozden, Derya Kivrak Salim, Semra Paydas, Atakan Demir, Omer Diker, Kezban Nur Pilanci, Özlem Uysal Sönmez, Sezai Vatansever, Izzet Dogan, Ahmet Gulmez, Burcu Cakar, Pinar Gursoy, Mahmut Emre Yildirim, Murat Ayhan, Nuri Karadurmus, Musa Baris Aykan, Gökcen Tugba Cevik, Teoman Sakalar, Ilhan Hacibekiroglu, Burcu Belen Gülbagci, Murat Dincer, Duygu Bayir Garbioglu, Yasemin Kemal, Erdinc Nayir, Halil Taskaynatan, Mesut Yilmaz, Okan Avci, Murat Sari, Ezgi Coban, Muhammed Mustafa Atci, Selin Aktürk Esen, Tugba Akin Telli, Fatih Karatas, Ali Inal, Hacer Demir, Nurhan Onal Kalkan, Cengiz Yilmaz, Funda Tasli, Ahmet Alacacioglu
In our study, we aimed to evaluate the pathological response rates and side effect profile of adding pertuzumab to the treatment of HER2+ locally advanced, inflammatory, or early-stage breast cancer. This study was conducted by the Turkish Oncology Group (TOG) with data collected from 32 centers. Our study was multicentric, and a total of 364 patients were included. The median age of the patients was 49 years (18-85 years). Two hundred fifteen (60%) of the cases were hormone receptor/HER2+ positive(ER+ or PR+, or both), and 149 (40%) of them were HER2-rich (ER and PR negative)...
August 1, 2022: Anti-cancer Drugs