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https://www.readbyqxmd.com/read/29233761/the-new-digit-tourniquet-forgetmenot%C3%A2
#1
J J Hidalgo Díaz, L Muresan, S Touchal, N Bahlouli, P Liverneaux, S Facca
BACKGROUND: Digit tourniquets are widely used in the operating room and even more often in the emergency department to allow the exploration of injuries. A rolled surgical glove finger or silicone catheter placed at the base of the digit is a common method. However, rolled glove tourniquets are easily forgotten under the dressing and may then cause ischaemia, which may require amputation. Silicone catheters are expensive single-use devices that may fail to provide effective exsanguination and must be removed by cutting, which may result in skin lesions...
December 9, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29224659/bronchial-artery-embolization-for-the-treatment-of-acute-hemoptysis
#2
M Cody O'Dell, Anne E Gill, C Matthew Hawkins
Massive hemoptysis is a life-threatening condition often defined as coughing up 300-600mL of blood in 24 hours in an adult, or >8mL/kg in 24 hours in a child. Although the definition is controversial, one should view massive hemoptysis as any volume of expectorated blood that can cause respiratory failure. This is because mortality in the setting of hemoptysis is usually associated with asphyxiation, rather than exsanguination. Massive hemoptysis accounts for only about 5% of cases of hemoptysis, but when treated conservatively, has a reported mortality rate between 50% and 85%...
December 2017: Techniques in Vascular and Interventional Radiology
https://www.readbyqxmd.com/read/29206488/structural-and-functional-evidence-for-the-scaffolding-effect-of-alveolar-blood-vessels
#3
Barry C Gibney, Willi L Wagner, Alexandra B Ysasi, Janeil M Belle, Akira Tsuda, Maximilian Ackermann, Steven J Mentzer
A contribution of pulmonary blood distension to alveolar opening was first proposed more than 100 years ago. To investigate the contribution of blood distension to lung mechanics, we studied control mice (normal perfusion), mice after exsanguination (absent perfusion) and mice after varying degrees of parenchymal resection (supra-normal perfusion). On inflation, mean tracheal pressures were higher in the bloodless mouse (4.0 ± 2.5 cm H2O); however, there was minimal difference between conditions on deflation (0...
December 5, 2017: Experimental Lung Research
https://www.readbyqxmd.com/read/29202212/nebulized-heparin-attenuates-pulmonary-coagulopathy-and-inflammation-through-alveolar-macrophages-in-a-rat-model-of-acute-lung-injury
#4
Laura Chimenti, Marta Camprubí-Rimblas, Raquel Guillamat-Prats, Maria Nieves Gomez, Jessica Tijero, Lluis Blanch, Antonio Artigas
Objective Alveolar macrophages play a key role in the development and resolution of acute respiratory distress syndrome (ARDS), modulating the inflammatory response and the coagulation cascade in lungs. Anti-coagulants may be helpful in the treatment of ARDS. This study investigated the effects of nebulized heparin on the role of alveolar macrophages in limiting lung coagulation and inflammatory response in an animal model of acute lung injury (ALI). Methods Rats were randomized to four experimental groups...
November 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/29198777/the-cyclin-dependent-kinase-2-cdk2-mediates-hematopoiesis-through-g1-to-s-transition-in-chinese-mitten-crab-eriocheir-sinensis
#5
Bin Yang, Yunke Jia, Zhihao Jia, Weilin Wang, Xiaorui Song, Yannan Li, Qilin Yi, Lingling Wang, Linsheng Song
Cyclin-dependent kinases (CDKs), a family of cell cycle-related serine/threonine kinases, participate in various biological processes, and play crucial roles in the innate immunity. In the present study, a CDK2 (designed as EsCDK2) with a serine/threonine protein kinase catalytic domain was identified from Chinese mitten crab (Eriocheir sinensis). The full-length cDNA sequence of EsCDK2 was of 2405 bp with an open reading frame (ORF) of 909 bp. EsCDK2 shared 66%-81% sequence similarities with previously identified CDK2s...
November 30, 2017: Developmental and Comparative Immunology
https://www.readbyqxmd.com/read/29197762/lamb-loin-tenderness-is-not-associated-with-plasma-indicators-of-pre-slaughter-stress
#6
S M Stewart, P McGilchrist, G E Gardner, D W Pethick
The purpose of this study was to test if associations exist between plasma indicators of acute and chronic stress and lamb loin Warner Bratzler Shear Force (WBSF). Blood was collected at exsanguination from 2877 lambs from the Meat and Livestock Genetic Research flock with a suite of indicators analysed. Loin (M. longissimus lumborum) WBSF was measured after 5days aging. Plasma indicators of stress did not relate to WBSF, however a positive association was found between WBSF and kill order, indicating that immediate pre-slaughter factors may be causing reduced tenderness in lamb...
November 23, 2017: Meat Science
https://www.readbyqxmd.com/read/29183321/effects-of-controlled-hypoxemia-or-hypovolemia-on-global-and-intestinal-oxygenation-and-perfusion-in-isoflurane-anesthetized-horses-receiving-an-alpha-2-agonist-infusion
#7
Klaus Hopster, Liza Wittenberg-Voges, Florian Geburek, Charlotte Hopster-Iversen, Sabine B R Kästner
BACKGROUND: Aim of this prospective experimental study was to assess effects of systemic hypoxemia and hypovolemia on global and gastrointestinal oxygenation and perfusion in anesthetized horses. Therefore, we anesthetized twelve systemically healthy warmblood horses using either xylazine or dexmedetomidine for premedication and midazolam and ketamine for induction. Anesthesia was maintained using isoflurane in oxygen with either xylazine or dexmedetomidine and horses were ventilated to normocapnia...
November 28, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29170169/thoracic-aortic-transection-resulting-in-a-type-b-dissection-following-blunt-trauma
#8
Lance Fogleman, Terrell Caffery, Jeffrey Gruner, Danielle Tatum
A 39-year-old man sustained an acute grade III aortic injury resulting in a type B aortic dissection in the setting of severe traumatic brain injury, cervical spine injury and multiple orthopaedic injuries following a motorcycle crash. The patient underwent an emergent thoracic endovascular aortic repair, complicated by a thoracic pseudoaneurysm rupture and ongoing exsanguination from a persistent type 1 endoleak. Additional stent grafts were required to gain control of the endoleak. The patient ultimately progressed to brain death post procedure in the intensive care unit...
November 23, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29150890/suspended-animation-the-past-present-and-future-of-major-cardiothoracic-trauma
#9
REVIEW
Syed Mohiyaddin, Prakash Nanjaiah, Ahmed O Saad, Metesh N Acharya, Tanveer A Khan, Rhodri H Davies, Saeed Ashraf
About 50% of the trauma victims die at the scene mostly because of exsanguinating haemorrhage. Most trials of resuscitation fail in face of the ongoing bleeding. Ongoing research/studies to save these victims by inducing rapid hypothermia using cardiopulmonary bypass as an emergency initial measure along with delayed resuscitation show improved outcomes. A comprehensive review of this research and analysis of studies showed that rapid induction of hypothermia within 5 min of cardiac arrest is associated with better survival and improved neurological outcome...
November 18, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29150225/nondisplaced-pubic-ramus-fracture-associated-with-exsanguination-and-death
#10
Chana Rich, James Rayner, Neha Raukar
We present a case of an elderly man who sustained non-displaced fractures through the right superior and inferior pubic rami after a fall from standing and had a tragic outcome. While minimally displaced pubic ramus fractures are typically stable and require only symptomatic treatment, there have been reports, such as this one, of low-energy pubic rami fractures resulting in massive hemorrhage. Despite aggressive resuscitation and embolization of the right obturator artery, our patient ultimately died during his hospitalization...
November 14, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29134171/endoscopic-endonasal-repair-of-internal-carotid-artery-injury-during-endoscopic-endonasal-surgery
#11
Irit Duek, Gill E Sviri, Moran Amit, Ziv Gil
Background  Injury to the cavernous portion of the internal carotid artery (ICA) during endoscopic skull base surgery is a well-recognized rare complication that can be associated with high rates of morbidity and mortality. Many techniques have been suggested to manage ICA injury with varying degrees of success. Objectives  We provide a detailed technical description of an operative technique for endoscopic management of carotid artery injury. Methods  A case of ICA injury during endoscopic skull base surgery is presented...
October 2017: Journal of Neurological Surgery Reports
https://www.readbyqxmd.com/read/29122112/prehospital-transfusion-for-gastrointestinal-bleeding
#12
Maile E Parker, Mohammad A Khasawneh, Cornelius A Thiels, Kathleen S Berns, James R Stubbs, Donald H Jenkins, Scott P Zietlow, Martin D Zielinski
OBJECTIVE: Gastrointestinal (GI) bleeding is a common medical emergency with significant morbidity and mortality. Many patients are coagulopathic, which may perpetuate bleeding. Remote damage control resuscitation, including early correction of coagulopathy and anemia, may benefit exsanguinating patients with GI bleeding. METHODS: We conducted a retrospective review of patients with acute GI bleeding who received packed red blood cells (pRBC) and/or plasma during transportation to our institution between 2010 and 2014...
November 2017: Air Medical Journal
https://www.readbyqxmd.com/read/29108049/body-fat-of-stock-type-horses-predicted-by-rump-fat-thickness-and-deuterium-oxide-dilution-and-validated-by-near-infrared-spectroscopy-of-dissected-tissues
#13
E N Ferjak, C A Cavinder, D D Burnett, C Mc Argo, T T N Dinh
Body condition score and percent body fat (BF; %) of horses are positively correlated with reproductive efficiency and are indicative of metabolic issues. However, BF in horses may be poorly predicted because current procedures are either subjective or dependent on one anatomical location. Therefore, the objectives of the current study were to compare 2 methods of predicting BF using rump fat thickness (RFT) and deuterium oxide (DO) dilution with actual tissue fat analysis by near-infrared spectroscopy (NIRS) in stock-type horses and to identify the relationship between BF and BCS...
October 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/29100664/tyrosine-hydroxylase-in-the-ventral-tegmental-area-of-rams-with-high-or-low-libido-a-role-for-dopamine
#14
A C Kramer, A J Mirto, K J Austin, C E Roselli, B M Alexander
Dopamine synthesis in the ventral tegmental area (VTA) is necessary for the reinforcement of sexual behavior. The objective of this study determined if sexual stimuli initiates reward, and whether reward is attenuated in sexually inactive rams. Sexually active rams were exposed to urine from estrous (n=4) or ovariectomized (n=3) ewes with inactive rams (n=3) exposed to urine from estrous ewes. Following exposure, rams were exsanguinated and brains perfused. Alternating sections of the VTA were stained for Fos related antigens (FRA), tyrosine hydroxylase, and dopamine beta-hydroxylase activity...
October 31, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/29095714/current-trends-in-the-management-of-hemodynamically-unstable-pelvic-ring-injuries
#15
Philip F Stahel, Clay C Burlew, Ernest E Moore
PURPOSE OF REVIEW: Complex traumatic pelvic ring disruptions are associated with a high mortality rate due to associated retroperitoneal hemorrhage, traumatic-hemorrhagic shock, and postinjury coagulopathy. The present review provides an update on current management strategies to improve survival rates form hemodynamically unstable pelvic ring injuries. RECENT FINDINGS: Recently published international consensus guidelines have attempted to standardize the classification of hemodynamically unstable pelvic ring injuries and provided classification-based management algorithms for acute resuscitation and pelvic ring stabilization...
December 2017: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/29084351/arterial-perfusion-a-useful-technique-for-evaluating-incised-wounds
#16
Neil E I Langlois, Roger W Byard
A 54-year-old woman was found deceased with incised wounds of both sides of her neck and both wrists. Postmortem CT scanning revealed air in the heart and in the dural veins in continuity with air in the right jugular vein. Death was due to incised wounds of the wrist and neck with blood loss and air embolism. The manner of death was suicide. At autopsy, perfusion of the thoracic ascending aorta produced a fine stream of water emanating from an incised wound of the right ulnar artery with no significant leakage of water from the wound of the left wrist...
October 30, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/29076325/a-shark-attack-treated-in-a-tertiary-care-centre-case-report-and-review-of-the-literature
#17
Melissa Roy, Mathew Plant, Laura Snell
Although uncommon, shark attacks can lead to devastating outcomes for victims. Surgeons also face unique challenges during operative management such as exsanguination, shock, specific injury patterns and infections. This case report presents the management of a 39-year-old previously healthy female attacked by a shark while on vacation in Mexico. The patient sustained severe injuries to her left arm and her left thigh. She was transferred to a Canadian institution after ambiguous operative management in Mexico and presented with no clear antibiotic coverage and a Volkman's contracture of the left upper extremity...
October 27, 2017: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/29071249/determination-of-plasmatic-cortisol-for-evaluation-of-animal-welfare-during-slaughter
#18
Edmondo Ceci, Patrizia Marchetti, Giorgio Samoilis, Stefano Sportelli, Rocco Roma, Roberta Barrasso, Giuseppina Tantillo, Giancarlo Bozzo
The plasmatic cortisol levels of 60 eight-month-old calves (Charolais breed) were measured as stress indicators resulting from two types of slaughter: traditional and religious rite. The plasmatic cortisol levels were evaluated during three different stages of their productive life: during growth, after transport and during slaughter. The thirty calves slaughtered after stunning showed plasmatic cortisol values of 4.85±3.2; 36.36±12.2 and 45.08±14.1 nmol/L, during growth, in the slaughterhouse stables and during exsanguination, respectively...
August 16, 2017: Italian Journal of Food Safety
https://www.readbyqxmd.com/read/29067785/pre-hospital-transfusion-of-red-blood-cells-in-civilian-trauma-patients
#19
M Rehn, A E Weaver, S Eshelby, J Røislien, D J Lockey
INTRODUCTION: The current management of severely injured patients includes damage control resuscitation strategies that minimise the use of crystalloids and emphasise earlier transfusion of red blood cells (RBC) to prevent coagulopathy. In 2012, London's air ambulance (LAA) became the first UK civilian pre-hospital service to routinely carry RBC to the trauma scene. OBJECTIVE: To investigate the effect of pre-hospital RBC transfusion (phRTx) on overall blood product consumption...
October 24, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/29042740/arteriovenous-malformation-of-face
#20
Ashok Kumar, Meenu Mittal, Dhirendra Srivastava, Vipul Jaetli, Sunil Chaudhary
Arteriovenous malformations (AVMs) are rare congenital vascular malformations accounting only 1.5% of all vascular anomalies with 50% occurrence in the oral and maxillofacial region. It usually results from birth defects of the vasculature. A literature search revealed only few case reports of AVMs in the facial region. Lack of meticulous diagnosis, scarcity of knowledge, and paucity of literature can result in their exsanguinations leading to fatal hemorrhagic incidents after various dental procedures such as tooth extraction, surgical intervention, puncture wound, or blunt injury in involved area...
July 2017: Contemporary Clinical Dentistry
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