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https://www.readbyqxmd.com/read/29148894/metabolic-profile-in-patients-with-mild-obstructive-sleep-apnea
#1
Luciana Oliveira E Silva, Thais M Guimarães, Gabriela P Luz, Glaury Coelho, Luciana Badke, Ildonete R Almeida, Aline Millani-Carneiro, Sergio Tufik, Lia Bittencourt, Sonia M Togeiro
BACKGROUND: Mild obstructive sleep apnea (OSA) is a highly prevalent disorder in adults. However, it is not clear whether mild OSA has significant metabolic complications. This study examined the prevalence of metabolic syndrome (MS) in patients with mild OSA compared to control group. METHODS: Adults (18-65 years of age) of both genders with a body mass index (BMI) ≤35 kg/m(2) were included. The mild OSA group comprised of patients with an apnea-hypopnea index (AHI) score of ≥5 but ≤15 events/hr of sleep, independent of other symptoms...
November 17, 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/29146165/preliminary-results-of-arthroscopic-superior-capsule-reconstruction-with-dermal-allograft
#2
Patrick J Denard, Paul C Brady, Christopher R Adams, John M Tokish, Stephen S Burkhart
PURPOSE: The purpose of this study was to evaluate the short-term outcomes of arthroscopic superior capsule reconstruction (SCR) with dermal allograft for the treatment of irreparable massive rotator cuff tears (MRCTs). METHODS: A multicenter study was performed on patients undergoing arthroscopic SCR for irreparable MRCTs. The minimum follow-up was 1 year. Range of motion and functional outcome according to visual analog scale (VAS) pain, American Shoulder and Elbow Surgeons (ASES) score, and subjective shoulder value (SSV) score were assessed preoperatively and at final follow-up...
November 13, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29145741/a-cohort-approach-to-real-time-detection-of-acute-hiv-infections-among-people-who-inject-drugs-in-st-petersburg-russia
#3
Olga Toussova, Andrei Kozlov, Sergei Verevochkin, Kathryn Lancaster, Alla Shaboltas, Alexey Masharsky, Elena Dukhovlinova, William C Miller, Irving Hoffman
OBJECTIVES: To detect acute HIV infections (AHI) in real time among people who inject drugs (PWID) in St. Petersburg, Russia and to test the feasibility of this approach. DESIGN: Prospective cohort study. METHODS: 100 seronegative or acutely HIV-infected at screening PWID were enrolled and followed until the end of the 12 month pilot period. Each participant was evaluated, tested and counseled for HIV monthly. Two HIV tests were used: HIV antibody and HIV RNA PCR...
November 16, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/29129030/effects-of-cpap-and-mandibular-advancement-device-treatment-in-obstructive-sleep-apnea-patients-a-systematic-review-and-meta-analysis
#4
REVIEW
Martha Schwartz, Luis Acosta, Yuan-Lung Hung, Mariela Padilla, Reyes Enciso
The purpose of this review is to conduct a systematic review and meta-analysis comparing the effects of continuous positive airway pressure (CPAP) with a mandibular advancement device (MAD) in improving the quality of life (sleepiness, cognitive, and functional outcomes) in patients diagnosed with obstructive sleep apnea (OSA). Authors identified randomized, placebo-controlled studies from MEDLINE through PubMed, Web of Science, and the Cochrane Library. Studies were assessed for inclusion and exclusion criteria, as well as risk of bias...
November 11, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29121334/pharmacotherapy-of-apnea-by-cannabimimetic-enhancement-the-pace-clinical-trial-effects-of-dronabinol-in-obstructive-sleep-apnea
#5
David W Carley, Bharati Prasad, Kathryn J Reid, Roneil Malkani, Hryar Attarian, Sabra M Abbott, Boris Vern, Hui Xie, Chengbo Yuan, Phyllis Zee
Study Objectives: There remains an important and unmet need for fully effective and acceptable treatments in obstructive sleep apnea (OSA). At present, there are no approved drug treatments. Dronabinol has shown promise for OSA pharmacotherapy in a small dose-escalation pilot study. Here, we present initial findings of the Phase II PACE (Pharmacotherapy of Apnea by Cannabimimetic Enhancement) trial, a fully-blinded parallel groups, placebo-controlled randomized trial of dronabinol in patients with moderate or severe OSA...
November 7, 2017: Sleep
https://www.readbyqxmd.com/read/29118860/coronary-flow-reserve-is-impaired-in-patients-with-obstructive-sleep-apnea
#6
Serife Savas Bozbas, Serpil Eroglu, Berna Akinci Ozyurek, Fusun Oner Eyuboglu
STUDY OBJECTIVES: Obstructive sleep apnea (OSA) is common in adult populations. Accumulating data indicate that it is independently associated with a variety of cardiovascular diseases and has prognostic importance in affected cases. In this study, we aimed to evaluate coronary flow reserve (CFR) in patients with OSA and controls. METHODS: Sixty-one patients undergoing an overnight polysomnography were enrolled in this study. Patients with an apnea-hypopnea index (AHI) >5 were accepted as OSA group (n = 45) and those with an AHI <5 were taken as controls (n = 16)...
October 2017: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29117883/admission-criteria-for-children-with-obstructive-sleep-apnea-after-adenotonsillectomy-considerations-for-cost
#7
David F Smith, Charlene P Spiceland, Stacey L Ishman, Branden M Engorn, Christopher Donohue, Paul S Park, James R Benke, Tiffany Frazee, Robert H Brown, Nicholas M Dalesio
STUDY OBJECTIVES: Postoperative respiratory complications (PRCs) are common among children with obstructive sleep apnea (OSA) after adenotonsillectomy. We analyzed postoperative admission guidelines to determine which optimally balanced patient safety and cost. METHODS: Retrospective study of children aged 12 years or younger undergoing adenotonsillectomy for OSA after polysomnography at a tertiary academic care center over 2 years. Demographics, medical history, and hospital course were collected...
November 1, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29115191/risk-factors-for-the-efficacy-of-oral-appliance-for-treating-obstructive-sleep-apnea-a-preliminary-study
#8
Geun-Shin Lee, Hye-Kyoung Kim, Mee-Eun Kim
Objective To identify potential risk factors of response to oral appliance in patients with obstructive sleep apnea (OSA). Methods Fifteen OSA patients were enrolled. Clinical characteristics, cephalometric measurements, and the results of home sleep testing were retrospectively obtained at baseline, and a sleep test was done again at the end of treatment. Results Twelve subjects were responders and three were non-responders. The diastolic blood pressure, minimum pulse rate, SNA (Angle between sella-nasion and nasion-A point), ANB (Anteroposterior maxilla/mandible discrepancy), and facial convexity of non-responders was higher than those of responders...
November 8, 2017: Cranio: the Journal of Craniomandibular Practice
https://www.readbyqxmd.com/read/29113702/mandibular-advancement-for-adult-obstructive-sleep-apnea-a%C3%A2-systematic-review-and-meta-analysis
#9
REVIEW
Michael W Noller, Christian Guilleminault, Christopher J Gouveia, Douglas Mack, Charles Vivian, Jose Abdullatif, Stefano Mangili, Stanley Yung Liu, Soroush Zaghi, Macario Camacho
OBJECTIVES: Patients with mandibular insufficiency can be predisposed to obstructive sleep apnea (OSA). The objective of this study was to systematically review the international literature for mandibular advancement surgeries (MAS) as treatment for adult OSA, and then to perform a meta-analysis. METHODS: Four authors searched five databases from the inception of each database through April 5, 2017. The PRISMA statement was followed. RESULTS: 972 studies were screened, 84 were downloaded, and 11 (57 patients) met criteria...
October 13, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29112823/obstructive-sleep-apnea-during-rapid-eye-movement-sleep-and-cardiovascular-disease
#10
R Nisha Aurora, Ciprian Crainiceanu, Daniel J Gottlieb, Ji Soo Kim, Naresh M Punjabi
BACKGROUND: Obstructive sleep apnea (OSA) during rapid eye movement (REM) sleep is a common disorder. Data on whether OSA that occurs predominantly during REM sleep is associated with health outcomes are limited. The present study examined the association between OSA during REM sleep and a composite cardiovascular endpoint in a community sample with and without prevalent cardiovascular disease. METHODOLOGY: Full montage home polysomnography was conducted as part of the Sleep Heart Health Study...
November 7, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29112186/connection-between-bone-remodeling-and-inflammatory-markers-in-obstructive-sleep-apnea-in-relation-to-disease-severity
#11
Barbara Bromińska, Ewa Cyrańska-Chyrek, Barbara Kuźnar-Kamińska, Magdalena Kostrzewska, Hanna Winiarska, Nadia Sawicka-Gutaj, Ariadna Zybek-Kocik, Aleksandra Hernik, Elżbieta Wrotkowska, Zbigniew Krasiński, Marek Ruchała, Halina Batura-Gabryel
INTRODUCTION    There is growing evidence that obstructive sleep apnea (OSA) influences both bone metabolism and structure. Chitinase-3-like protein 1 (YKL-40) is a novel inflammatory and remodeling marker, which was shown to increase in OSA. YKL-40 can probably alter the bone turnover.   OBJECTIVES    Assessment of a possible interplay between YKL-40 and bone turnover markers in patients with different stages of OSA. Evaluation of the relation among bone mass, OSA severity, and YKL-40 level. PATIENTS AND METHODS    The study is based on 72 male OSA patients divided into three groups according to disease severity using apnea-hypopnea index (AHI): OSA 1 n = 18 (5 ≤ AHI < 15), OSA 2 n = 25 (15 ≤ AHI < 30), OSA 3 n = 29 (AHI ≥ 30)...
November 7, 2017: Polish Archives of Internal Medicine
https://www.readbyqxmd.com/read/29109068/obstructive-sleep-apnea-in-women-study-of-speech-and-craniofacial-characteristics
#12
Marina Tyan, Fernando Espinoza-Cuadros, Rubén Fernández Pozo, Doroteo Toledano, Eduardo Lopez Gonzalo, Jose Daniel Alcazar Ramirez, Luis Alfonso Hernandez Gomez
BACKGROUND: Obstructive sleep apnea (OSA) is a common sleep disorder characterized by frequent cessation of breathing lasting 10 seconds or longer. The diagnosis of OSA is performed through an expensive procedure, which requires an overnight stay at the hospital. This has led to several proposals based on the analysis of patients' facial images and speech recordings as an attempt to develop simpler and cheaper methods to diagnose OSA. OBJECTIVE: The objective of this study was to analyze possible relationships between OSA and speech and facial features on a female population and whether these possible connections may be affected by the specific clinical characteristics in OSA population and, more specifically, to explore how the connection between OSA and speech and facial features can be affected by gender...
November 6, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29108917/subcranial-and-orthognathic-surgery-for-obstructive-sleep-apnea-in-achondroplasia
#13
Srinivas M Susarla, Gerhard S Mundinger, Hitesh Kapadia, Mark Fisher, James Smartt, Christopher Derderian, Amir Dorafshar, Richard A Hopper
PURPOSE: Obstructive sleep apnea (OSA) is a common problem in patients with achondroplasia. The purpose of this study was to assess changes in airway volumes following various degrees of facial skeletal advancement. METHODS: This was a retrospective evaluation of patients with achondroplasia who underwent facial skeletal advancement for obstructive sleep apnea. Patients were treated with either an isolated Le Fort III distraction (LF3) or Le Fort II distraction with or without subsequent Le Fort I and bilateral sagittal split osteotomies (LF2 ± LF1/BSSO)...
October 5, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29106880/utility-of-screening-questionnaire-and-polysomnography-to-predict-postoperative-outcomes-in-children
#14
Hiromi Kako, Jennifer Tripi, Hina Walia, Dmitry Tumin, Mark Splaingard, Kris R Jatana, Joseph D Tobias, Vidya T Raman
INTRODUCTION: The prevalence of pediatric obstructive sleep apnea (OSA) has increased concurrently with the increasing prevalence of obesity. We have previously validated a short questionnaire predicting the occurrence of OSA on polysomnography (PSG). This follow-up study assessed the utility of the questionnaire in predicting postoperative outcomes. METHODS: Children undergoing surgery and completing a sleep study were prospectively screened for OSA using a short questionnaire...
November 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29105336/sleep-quality-and-quality-of-life-in-patients-with-moderate-to-very-severe-copd
#15
Buket Akinci, Gökşen Kuran Aslan, Esen Kiyan
INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is highly associated with Obstructive Sleep Apnea (OSA). Poor sleep quality found related with decreased quality of life in COPD patients but no study assessed this relationship on the basis of nocturnal sleep parameters. OBJECTIVES: The aim of this study is to explore relationships between sleep quality, daytime sleepiness, and quality of life in moderate to very severe COPD patients with and without sleep apnea assessed objectively and compare sleep quality, quality of life and daytime sleepiness in COPD patients with and without sleep apnea...
November 4, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29102064/modified-z-palatoplasty-with-one-layer-closure-in-one-stage-multilevel-surgery-for-severe-obstructive-sleep-apnea
#16
Ethan I Huang, Chia-Ling Kuo, Yu-Ting Chou, Yu-Ching Lin, Shu-Yi Huang
OBJECTIVE: The meticulous two-layer closure is a step to complete the modified Z-palatoplasty, which has been reported to serve as an effective element in multilevel sleep surgery for patients with severe obstructive sleep apnea, especially with Friedman anatomical stages II and III diseases. A single layer closure-the suture closure as originally described in uvulopalatopharyngoplasty by Fujita et al., is an alternative of the two-layer closure, featured by simplicity while its efficacy has not been completely proved in patients with severe obstructive sleep apnea...
October 25, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29101760/sexual-dysfunction-in-premenopausal-women-with-obstructive-sleep-apnea
#17
Zahide Yilmaz, Pinar Bekdik Sirinocak, Bekir Voyvoda, Levent Ozcan
PURPOSE: Sexual functions in the males with obstructive sleep apnea syndrome (OSAS) have been well investigated in the literature; however sexual functions in the premenopausal women with OSAS have been studied to a lesser extent. MATERIALS AND METHODS: The study included 22 premenopausal women diagnosed as OSAS by the polysomnographic (PSG) evaluation. The control group included 13 premenopausal women suspected of sleep-relatedrespiratory disorder, but whose PSG tests were determined to be normal...
November 4, 2017: Urology Journal
https://www.readbyqxmd.com/read/29098288/hypoglossal-nerve-stimulation-in-adolescents-with-down-syndrome-and-obstructive-sleep-apnea
#18
Gillian R Diercks, Carissa Wentland, Donald Keamy, Thomas Bernard Kinane, Brian Skotko, Vanessa de Guzman, Ellen Grealish, John Dobrowski, Ryan Soose, Christopher J Hartnick
Importance: Obstructive sleep apnea (OSA) affects up to 60% of children with Down syndrome (DS) and may persist in half of patients after adenotonsillectomy. Children with DS who have persistent OSA often do not tolerate treatment with positive pressure airway support devices or tracheotomy for their residual moderate to severe OSA. The hypoglossal nerve stimulator is an implantable device that delivers an electrical impulse to anterior branches of the hypoglossal nerve in response to respiratory variation, resulting in tongue base protrusion that alleviates upper airway obstruction in adults...
November 2, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29096240/features-of-continuous-glycemic-profile-and-glycemic-variability-in-patients-with-obstructive-sleep-apnea-syndrome
#19
Chao-Sheng Peng, Yue-An Cao, Yu-Hong Tian, Wen-Luo Zhang, Jing Xia, Lu Yang
AIMS: To investigate glycemic variability (GV) in Obstructive Sleep Apnea Syndrome (OSAS) patients by monitoring continuous blood glucose profile. METHODS: OSAS group (n=86) and normal control group (n=40) were included. Continuous blood glucose was monitored. The relationship of GV, insulin resistance index (IRI) and the respiratory disturbance index (AHI) were analyzed. RESULTS: The daily average blood glucose level was significantly higher in the OSAS patients than in the control group (6...
August 20, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29094076/friedman-tongue-position-and-cone-beam-computed-tomography-in-patients-with-obstructive-sleep-apnea
#20
Rebecca Harvey, Louise O'Brien, Sharon Aronovich, Anita Shelgikar, Paul Hoff, John Palmisano, Jeffrey Stanley
Objective: Evaluate the correlation between Friedman Tongue Position (FTP) and airway cephalometrics in patients with obstructive sleep apnea (OSA). Study Design: Retrospective review of adult patients with OSA undergoing Cone Beam Computed Tomography (CBCT). Methods: Collected data included age, sex, body mass index, apnea hypopnea index, FTP, and airway cephalometric parameters. Data analyses were performed using ANOVA, dichotomous t-testing, and linear regression...
October 2017: Laryngoscope Investigative Otolaryngology
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