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Spine implants

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https://www.readbyqxmd.com/read/29789873/new-implant-based-technologies-in-the-spine
#1
Dimitrios K Filippiadis, Stefano Marcia, Anthony Ryan, Douglas P Beall, Salvatore Masala, Frederic Deschamps, Alexis Kelekis
Vertebral compression fractures (VCFs) may result in a kyphotic deformity which can cause potential systemic complications secondary to respiratory and gastrointestinal dysfunction. The use of implants in the spine for VCF treatment represents a paradigm shift away from cement injection on its own, aiming to combine the analgesic and stabilizing effect of injecting cement into the vertebral body with vertebral height restoration and kyphotic angle correction. Spine implants which can be used for VCF treatment include stents, jacks, PEEK cages and fracture reduction systems...
May 22, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29780802/exploring-the-potential-of-generative-adversarial-networks-for-synthesizing-radiological-images-of-the-spine-to-be-used-in-in-silico-trials
#2
Fabio Galbusera, Frank Niemeyer, Maike Seyfried, Tito Bassani, Gloria Casaroli, Annette Kienle, Hans-Joachim Wilke
In silico trials recently emerged as a disruptive technology, which may reduce the costs related to the development and marketing approval of novel medical technologies, as well as shortening their time-to-market. In these trials, virtual patients are recruited from a large database and their response to the therapy, such as the implantation of a medical device, is simulated by means of numerical models. In this work, we propose the use of generative adversarial networks to produce synthetic radiological images to be used in in silico trials...
2018: Frontiers in Bioengineering and Biotechnology
https://www.readbyqxmd.com/read/29766758/anti-inflammatory-peptide-attenuates-edema-and-promotes-bmp-2-induced-bone-formation-in-spine-fusion
#3
Juliane D Glaeser, Khosrowdad Salehi, Linda Kanim, Dmitriy Sheyn, Zachary NaPier, Phillip Behrens, Leslie Garcia, Jason M Cuéllar, Hyun W Bae
Recombinant human bone morphogenic protein-2 (BMP-2) loaded absorbable collagen sponges (ACS) have been successfully used to enhance bone formation and to induce spinal fusion in humans. However, side effects, such as soft-tissue edema and inflammation, have been reported. NEMO binding domain peptide (NBD) inhibits activation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), a central regulator of immune response. In this study, we investigated NBD's potential to reduce BMP-2-induced soft-tissue inflammation without affecting BMP-2-mediated spinal fusion in rat...
May 16, 2018: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/29761298/lumbar-muscle-atrophy-caused-by-harness-replacement-in-a-chronic-calf-model-of-total-artificial-heart-implantation
#4
Jamshid H Karimov, Kimberly A Such, Raymond Dessoffy, Kiyotaka Fukamachi
The postoperative care of animals implanted with mechanical circulatory support devices is complex. The standard of care requires continuous monitoring of hemodynamic parameters post implant, wound care, and maintenance of the animal's well-being, but also includes controlling the animal's biomechanics under conditions of continuous restraint and harnessing. In such studies, a harness provides secure fixation of the exteriorized device driveline and pressure lines and aids animal handling (lifting, position adjustment, and assistance with standing up)...
May 14, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29760731/recovery-of-donor-hematopoiesis-after-graft-failure-and-second-hematopoietic-stem-cell-transplantation-with-intraosseous-administration-of-mesenchymal-stromal-cells
#5
Nataliya Petinati, Nina Drize, Natalia Sats, Natalya Risinskaya, Andrey Sudarikov, Michail Drokov, Daria Dubniak, Alina Kraizman, Maria Nareyko, Natalia Popova, Maya Firsova, Larisa Kuzmina, Elena Parovichnikova, Valeriy Savchenko
Multipotent mesenchymal stromal cells (MSCs) participate in the formation of bone marrow niches for hematopoietic stem cells. Donor MSCs can serve as a source of recovery for niches in patients with graft failure (GF) after allogeneic bone marrow (BM) transplantation. Since only few MSCs reach the BM after intravenous injection, MSCs were implanted into the iliac spine. For 8 patients with GF after allo-BMT, another hematopoietic stem cell transplantation with simultaneous implantation of MSCs from their respective donors into cancellous bone was performed...
2018: Stem Cells International
https://www.readbyqxmd.com/read/29758566/long-term-results-for-the-bacjac-interspinous-device-in-lumbar-spine-degenerative-disease
#6
Aldo Spallone, Luigi Lavorato, Daniele Belvisi
OBJECTIVE:  To evaluate the long-term results of using the BacJac interspinous device (Pioneer Surgical Technology Inc.) in a series of patients with degenerative lumbar spine disease. METHODS:  Forty-one patients undergoing lumbar surgery with implantation of a BacJac device from 2009 to 2012 were enrolled in the present study. Patients were evaluated using the Oswestry Disability Scale (ODI). RESULTS:  Although all patients showed a significant improvement of the ODI score immediately after surgery, only 41% of patients showed a satisfactory outcome...
May 14, 2018: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/29755233/cervical-lift-up-laminoplasty-with-titanium-basket-plates-after-resection-of-intradural-tumor
#7
Keisuke Shirosaka, Kentaro Naito, Toru Yamagata, Masaki Yoshimura, Kenji Ohata, Toshihiro Takami
Background: Performing cervical laminoplasty after wide laminectomy may be technically demanding. The unique technique of cervical lift-up laminoplasty using titanium basket plates was applied for the reconstruction of cervical laminae after wide laminectomy for the resection of intradural tumors. Materials and Methods: This technical study included 14 cases that could be followed periodically for at least 6 months after surgery. Participants were 8 male and 6 female, with a mean age of 41...
January 2018: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/29755232/augmentation-of-fenestrated-pedicle-screws-with-cement-in-patients-with-osteoporotic-spine
#8
Mahmoud Abousayed, Joseph Gamal Boktor, Ahmed Maher Sultan, Wael Koptan, Yasser El-Miligui
Background: Backing out and failure of pedicle screws in patients with osteoporosis is becoming a big problem due to wide use of these screws nowadays. Purpose: The aim of this study is to evaluate the purchase of fenestrated pedicle screws augmented with cement in patients with osteoporosis. Study Design: This was retrospective observational study. Patients and Methods: From May 2015 to January 2016, 25 patients with a poor bone stock condition underwent posterior fixation by fenestrated pedicle screws and cement augmentation...
January 2018: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/29752555/minimally-invasive-surgery-procedure-in-isthmic-spondylolisthesis
#9
Francesco Ciro Tamburrelli, Maria Concetta Meluzio, Aaron Burrofato, Andrea Perna, Luca Proietti
PURPOSE: The aim of the study was to evaluate the efficacy and safety of the direct lateral approach to the lumbar spine in the treatment of painful isthmic spondylolisthesis in adults. METHODS: Twenty-one patients affected by isthmic spondylolisthesis and treated with extreme lateral interbody fusion and posterior percutaneous pedicle screw fixation were enrolled. All included patients were clinically evaluated with Oswestry Disability Index, SF36 and Visual Scale Anatomy (VAS) for back pain at 1, 3 months and at 1 year...
May 11, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29749048/evaluation-of-projection-and-dual-energy-based-methods-for-metal-artifact-reduction-in-ct-using-a-phantom-study
#10
Zaiyang Long, Michael R Bruesewitz, David R DeLone, Jonathan M Morris, Kimberly K Amrami, Mark C Adkins, Katrina N Glazebrook, James M Kofler, Shuai Leng, Cynthia H McCollough, Joel G Fletcher, Ahmed F Halaweish, Lifeng Yu
OBJECTIVES: Both projection and dual-energy (DE)-based methods have been used for metal artifact reduction (MAR) in CT. The two methods can also be combined. The purpose of this work was to evaluate these three MAR methods using phantom experiments for five types of metal implants. MATERIALS AND METHODS: Five phantoms representing spine, dental, hip, shoulder, and knee were constructed with metal implants. These phantoms were scanned using both single-energy (SE) and DE protocols with matched radiation output...
May 10, 2018: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/29747017/a-novel-association-between-intrathecal-drug-administration-and-arachnoiditis-ossificans
#11
Max Ward, Antonios Mammis, Maureen T Barry, Robert F Heary
We present a case of delayed progression of adhesive arachnoiditis to arachnoiditis ossificans (AO) in a patient being treated with a high dose polypharmaceutical intrathecal regimen. The patient is a 39-year-old Caucasian male who was implanted with an intrathecal pump in 2006 to control severe low back pain and administered intrathecal pain medication for a period of 10 years. In 2016, he developed new onset radicular pain and worsened sensation in his lower extremities. A CT scan of the lumbar spine at that time demonstrated profound calcification of the arachnoid consistent with a diagnosis of AO...
May 7, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29744453/studies-on-the-cytocompatibility-mechanical-and-antimicrobial-properties-of-3d-printed-poly-methyl-methacrylate-beads
#12
David K Mills, Uday Jammalamadaka, Karthik Tappa, Jeffery Weisman
Osteomyelitis is typically a bacterial infection (usually from Staphylococcus) or, more rarely, a fungal infection of the bone. It can occur in any bone in the body, but it most often affects the long bones (leg and arm), vertebral (spine), and bones of the foot. Microbial success in osteomyelitis is due to their ability to form biofilms which inhibit the wound healing process and increases resistance to anti-infective agents. Also, biofilms do not allow easy penetration of antibiotics into their matrix making clinical treatment a challenge...
June 2018: Bioactive Materials
https://www.readbyqxmd.com/read/29740675/biomechanical-advantages-of-supplemental-accessory-and-satellite-rods-with-and-without-interbody-cages-implantation-for-the-stabilization-of-pedicle-subtraction-osteotomy
#13
Luigi La Barbera, Marco Brayda-Bruno, Christian Liebsch, Tomaso Villa, Andrea Luca, Fabio Galbusera, Hans-Joachim Wilke
PURPOSE: To investigate the effect of anterior interbody cages, accessory and satellite rods usage on primary stability and rod strains for PSO stabilization. METHODS: Seven human cadaveric spine segments (T12-S1) underwent PSO at L4 with posterior fixation from L2 to S1. In vitro flexibility tests were performed under pure moments in flexion/extension (FE), lateral bending (LB) and axial rotation (AR) to determine the range of motion, while measuring the strains on the primary rods with strain gauge rosettes...
May 8, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29736803/titanium-granules-pre-treated-with-hydrogen-peroxide-inhibit-growth-of-bacteria-associated-with-post-operative-infections-in-spine-surgery
#14
Acke Ohlin, Emma Mattsson, Matthias Mörgelin, Julia R Davies, Gunnel Svensäter, Stéphane Corvec, Pentti Tengvall, Kristian Riesbeck
PURPOSE: Post-operative infections are relatively common after posterior spine surgery, and there are several observations reflecting different infection complications related to various metals implanted. Here, we selected an array of different bacterial species that are often found in infections associated with orthopaedic implants and tested for inhibition by hydrogen peroxide-treated titanium (Ti-peroxy). METHODS: To study the possibility of using Ti-peroxy as an antimicrobial prophylaxis, we developed a protocol for standardized susceptibility testing of bacteria...
May 7, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29735145/growth-friendly-surgery-is-effective-at-treating-early-onset-scoliosis-associated-with-goldenhar-syndrome
#15
Braydon Connell, Jonathan J Oore, Joshua M Pahys, George H Thompson, Tricia St Hilaire, Tara Flynn, Ron El-Hawary
OBJECTIVE: To evaluate the radiographic results and complications of growth-friendly (GF) surgery in the treatment of early-onset scoliosis (EOS) associated with Goldenhar syndrome. BACKGROUND: Goldenhar syndrome has been associated with spinal deformity, which may be progressive. Efficacy and complication rate of GF treatment has not been reported for this population of patients with EOS. METHODS: Patients with Goldenhar syndrome and EOS with two years' follow-up were identified from two international multicenter EOS databases...
May 2018: Spine Deformity
https://www.readbyqxmd.com/read/29735144/construct-levels-to-anchored-levels-ratio-and-rod-diameter-are-associated-with-implant-related-complications-in-traditional-growing-rods
#16
Pooria Hosseini, Behrooz A Akbarnia, Stacie Nguyen, Jeff Pawelek, John Emans, Peter F Sturm, Paul D Sponseller
INTRODUCTION: In addition to patient characteristics, consideration of length of construct to number of anchored levels ratio and rod diameter should be a part of preoperative planning to minimize implant-related complications (IRCs). IRCs including rod breakage, anchor dislodgement, and pullout are among the most common adverse events in traditional growing rods (TGRs). The current study hypothesized that anchor type and configuration are associated with IRC. METHODS: Patients with (1) age ≤10 years at surgery; (2) spine-based dual TGR; (3) minimum 2-year follow-up; and (4) available imaging...
May 2018: Spine Deformity
https://www.readbyqxmd.com/read/29735140/surgeon-survey-shows-no-adverse-events-with-mri-in-patients-with-magnetically-controlled-growing-rods-mcgrs
#17
Regina P Woon, Lindsay M Andras, Hilali Noordeen, Stephen Morris, John Hutchinson, Suken A Shah, Jeff Pawelek, Charles E Johnston, David L Skaggs
STUDY DESIGN: Surgeon survey. OBJECTIVES: To determine if magnetic resonance imaging (MRI) following implantation of magnetically controlled growing rods (MCGRs) is associated with any adverse events. SUMMARY OF BACKGROUND DATA: Magnetically controlled growing rods have been shown to reduce the need for repeated surgical procedures and improve costs when compared to traditional growing rods, but concerns about MRI compatibility exist. MRIs are often clinically indicated in the EOS population...
May 2018: Spine Deformity
https://www.readbyqxmd.com/read/29733080/erratum-to-composite-peek-carbon-fiber-implants-can-increase-the-effectiveness-of-radiotherapy-in-the-management-of-spine-tumors
#18
(no author information available yet)
[This corrects the article DOI: 10.21037/jss.2017.06.20.].
March 2018: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29732428/minimum-ten-year-follow-up-of-spinal-stenosis-with-degenerative-spondylolisthesis-treated-with-decompression-and-dynamic-stabilization
#19
Kotryna Veresciagina, Arne Mehrkens, Stefan Schären, Bernhard Jeanneret
Background: The Dynesys system remains the most widely implanted posterior non-fusion pedicle screw system. Various study designs used in investigations with good to excellent short- and mid-term results have been reported in the current literature. However, there is a lack of information concerning long-term outcomes following treatment for spinal stenosis with degenerative spondylolisthesis. Methods: The aim of our study was twofold. Firstly, to assess whether the dynamic stabilization in situ with the Dynesys System without bone grafting provides enough stability to prevent progression of spondylolisthesis and secondarily to maintain significant clinical improvement in a long-term follow-up (FU)...
March 2018: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29726795/complication-rates-for-preexisting-baclofen-pumps-and-ventricular-shunts-following-scoliosis-correction-a-preliminary-study
#20
Jonathan Dallas, Katherine D Sborov, Bradley S Guidry, Silky Chotai, Christopher M Bonfield
OBJECTIVE Many patients undergoing spinal fusion for neuromuscular scoliosis have preexisting neurosurgical implants, including ventricular shunts (VSs) for hydrocephalus and baclofen pumps (BPs) for spastic cerebral palsy. Recent studies have discussed a possible increase in implant complication rates following spinal fusion, but published data are inconclusive. The authors therefore, sought to investigate: 1) the rate of implant complications following fusion, 2) possible causes of these complications, and 3) factors that place patients at higher risk for implant-related complications...
May 4, 2018: Journal of Neurosurgery. Pediatrics
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