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https://www.readbyqxmd.com/read/28430741/utility-of-8%C3%A2-h-and-time-decay-corrected-acquisition-scintigraphy-with-in-vitro-labeled-white-blood-cells-for-the-diagnosis-of-osteoarticular-infection
#1
Edel Noriega Álvarez, Guillermo A Martínez Pimienta, Ana M Benítez Segura, María T Bajén Lázaro, Alba Rodrígez-Gasén, Julio Rodríguez-Rubio Corona, Jaime Mora Salvadó
INTRODUCTION: Except in the spine, labeled white-blood cell scintigraphy (WBCS) with image acquisition up to 24 h is the nuclear medicine test of choice for diagnosing osteoarticular infection. However, distinguishing between inflammation and infection is a challenge. OBJECTIVES: The first aim of this study was to verify earlier research studies that used 4 and 24 h time decay-corrected acquisition (TDCA) to differentiate infection from inflammation. The second aim was to analyze whether 8 h acquisition (1-day protocol) yielded similar results as 20-24 h acquisition...
April 20, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28422833/correction-of-sagittal-imbalance-in-treatment-for-adult-degenerative-scoliosis-with-thoracic-lordosis-and-lumbar-kyphosis-a-case-report
#2
Tao Wang, Hui Wang, Lei Ma, Di Zhang, Wen-Yuan Ding
RATIONALE: Lumbar degenerative scoliosis (LDS) is a common spinal disease for senior citizens. However, LDS accompanied with thoracic lordosis and lumbar kyphosis (LK) is rare in clinic. No reports have reported LDS with thoracic lordosis and LK. PATIENT CONCERNS: A 54-year-old woman just complained about sever back pain without any radiculopathy and neurodeficit of low limb for 2 years, Visual Analogue Scale (VAS) for back pain was 9 points and x-ray showed adult LDS with lordosis angle of 10° from 5th thoracic to 12th thoracic (T5-T12) and LK angle of 20°...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28422797/response-to-the-letter-spinal-implants-can-be-inserted-in-patients-with-deep-spine-infection-results-from-a-large-cohort-study
#3
Hwee Weng Dennis Hey, Nathaniel Li Wen Ng, Chuen-Seng Tan, Dale Fisher, Anupama Vasudevan, Gabriel Ka-Po Liu, Joseph Thambiah, Naresh Kumar, Leok-Lim Lau, Hee-Kit Wong, Paul Anantharajah Tambyah
No abstract text is available yet for this article.
April 18, 2017: Spine
https://www.readbyqxmd.com/read/28410566/biomechanical-effect-of-interspinous-process-distraction-height-after-lumbar-fixation-surgery-an-in-vitro-model
#4
Lin Fu, Jianxiong Ma, Bin Lu, Haobo Jia, Jie Zhao, Mingjie Kuang, Rui Feng, Liyan Xu, Haohao Bai, Lei Sun, Ying Wang, Xinlong Ma
Pedicle screw fixation may induce abnormal activity at adjacent segment and accelerate the degeneration of lumbar vertebrae. Dynamic stabilizers could provide an intermediate solution between conservative treatment and fusion surgery. Lumbar vertebral segment cephalad to instrumented fixation was the most common localization of adjacent segment degeneration. The aim of this study is to explore the use of interspinous process devices in the lumbar vertebral segment cephalad to fixation segment in changing the mechanical distribution and limiting abnormal activity of the spine...
April 1, 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/28408260/evaluation-of-bioabsorbable-multiamino-acid-copolymer-nano-hydroxyapatite-calcium-sulphate-cage-in-a-goat-spine-model
#5
Chunpeng Ren, Yueming Song, Youdi Xue, Xi Yang, Chunguang Zhou
BACKGROUND: Recently, polylactide is the most popular material used to made bioabsorbable cages, but too fast degradation and osteolysis around the cage have been reported in the literature. This study evaluated the fusion effect, biomechanical stability and histological characteristics of a novel bioabsorbable multi-amino acid copolymer/nano-hydroxyapatite/calcium sulphate (MAACP/n-HA/CS) interbody cage in a goat model of anterior cervical discectomy and fusion (ACDF). METHODS: A total of 24 goats underwent C3/C4 discectomy and fusion with three groups of intervertebral implants: MAACP/n-HA/CS cage group (n = 8), titanium cage group (n = 8) and autologous tricortical iliac crest bone group (n = 8)...
April 10, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28402086/the-effect-of-increased-microporosity-on-bone-formation-within-silicate-substituted-scaffolds-in-an-ovine-posterolateral-spinal-fusion-model
#6
Melanie Jean Coathup, Gordon William Blunn, Charlie Campion, Chih-Yuan Ho, Karin Angela Hing
This study compared the bone forming capacity of the same formulation of silicate-substituted bone graft substitute materials with different microporosity in an instrumented posterolateral spinal fusion ovine model. Materials with a strut porosity of (i) 22.5% (SiCaP) or (ii) 36.0% (SiCaP(+)) were packed along either side of the spine. Bone apposition rates, % new bone formation, % bone-implant contact, and % graft resorption were quantified at 8, 12, and 24 weeks post surgery. Computed Tomography (CT) was used to grade the formation of fusion bridges between vertebrae...
May 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28399557/radiological-results-and-clinical-patient-outcome-after-implantation-of-a-hydraulic-expandable-vertebral-body-replacement-following-traumatic-vertebral-fractures-in-the-thoracic-and-lumbar-spine-a-3-year-follow-up
#7
Michael Kreinest, Dorothee Schmahl, Paul A Grützner, Stefan Matschke
STUDY DESIGN: A prospective monocentric study. OBJECTIVE: The aim of the current study was the analysis of patient outcome and radiological results 3 years after implantation of a hydraulic expandable vertebral body replacement (VBR) system. SUMMARY OF BACKGROUND DATA: Around 70% to 90% of all traumatic spinal fractures are located in the thoracic and lumbar spine. Dorso-ventral stabilization is a frequently used procedure in traumatic vertebral body fracture treatment...
April 15, 2017: Spine
https://www.readbyqxmd.com/read/28399544/intrawound-tobramycin-powder-eradicates-surgical-wound-contamination-an-in-vivo-rabbit-study
#8
Joseph L Laratta, Jamal N Shillingford, Nathan Hardy, Joseph M Lombardi, Comron Saifi, Alexander Romanov, Lawrence G Lenke, Ronald A Lehman, K Daniel Riew
STUDY DESIGN: Therapeutic anti-infective trial in rabbitsOBJECTIVE.: The purpose of the present study was to assess the efficacy of intrawound tobramycin powder in terms of eradicating a known bacterial contamination in an Escherichia coli infected rabbit spinal implantation model. SUMMARY OF BACKGROUND DATA: Implant-associated surgical site infections (SSI) remain a dreaded complication of spinal surgery. Currently, over 30% of all spine SSIs are secondary to gram-negative bacteria...
April 10, 2017: Spine
https://www.readbyqxmd.com/read/28399050/veptr-are-we-reducing-respiratory-assistance-requirements
#9
Sarah B Nossov, Evan Curatolo, Robert M Campbell, Oscar H Mayer, Sumeet Garg, Patrick J Cahill
BACKGROUND: The assisted ventilation rating (AVR) indicates the degree of external respiratory support required in children with thoracic insufficiency syndrome (TIS) and early onset scoliosis. For skeletally immature patients with TIS, the vertical expandable prosthetic titanium rib (VEPTR) device can be used to improve lung volume and growth. We hypothesized that patients who underwent early thoracic reconstruction by VEPTR treatment had an improved respiratory status. METHODS: Preoperative and postoperative AVR ratings were prospectively collected in a multicenter study group and compared with determine change after VEPTR treatment...
April 10, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28394747/risk-and-protective-factors-associated-with-surgical-infections-among-spine-patients
#10
REVIEW
Alyssa G Blood, Melanie F Sandoval, Evalina Burger, Katherine Halverson-Carpenter
BACKGROUND: The purpose of the study was to identify patient-specific and procedure-specific risk and protective factors associated with post-operative surgical site infections (SSIs) among surgical spine patients. METHODS: CINAHL, PubMed, Ovid, Medline, and EBSCO databases were searched for articles within the past 10 years (January 2003-March 2015). The keywords and combinations used in the search included: Spine surgery, post-operative infection, risk factors, orthopedic infections...
April 2017: Surgical Infections
https://www.readbyqxmd.com/read/28391382/insufficient-stability-of-pedicle-screws-in-osteoporotic-vertebrae-biomechanical-correlation-of-bone-mineral-density-and-pedicle-screw-fixation-strength
#11
Lukas Weiser, Gerd Huber, Kay Sellenschloh, Lennart Viezens, Klaus Püschel, Michael M Morlock, Wolfgang Lehmann
PURPOSE: Loosening of pedicle screws is one major complication of posterior spinal stabilisation, especially in the patients with osteoporosis. Augmentation of pedicle screws with cement or lengthening of the instrumentation is widely used to improve implant stability in these patients. However, it is still unclear from which value of bone mineral density (BMD) the stability of pedicle screws is insufficient and an additional stabilisation should be performed. The aim of this study was to investigate the correlation of bone mineral density and pedicle screw fatigue strength as well as to define a threshold value for BMD below which an additional stabilisation is recommended...
April 8, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28391381/osseointegration-improves-bone-implant-interface-of-pedicle-screws-in-the-growing-spine-a-biomechanical-and-histological-study-using-an-in-vivo-immature-porcine-model
#12
Kanako Shiba, Hiroshi Taneichi, Takashi Namikawa, Satoshi Inami, Daisaku Takeuchi, Yutaka Nohara
PURPOSE: Implant failure is a frequent complication in corrective surgery for early onset scoliosis, since considerable forces are acting on small and fragile vertebrae. Osseointegration showing biomechanical and histological improvement in bone-implant interface (BII) after dental implant placement has been well investigated. However, there are no studies regarding osseointegration in immature vertebral bone. The purpose was to evaluate the timecourse of biomechanical and histological changes at BII after pedicle screw placement using in vivo immature porcine model...
April 8, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28388735/a-novel-anterior-trans-pedicular-screw-artificial-vertebral-body-system-for-lower-cervical-spine-fixation-a-finite-element-study
#13
Weidong Wu, Chun Chen, Jinpei Ning, Pei-Dong Sun, Jinyuan Zhang, Changfu Wu, Zhenyu Bi, Jihong Fan, Xianliang Lai, Jun Ouyang
Objective A finite element model was used to compare the biomechanical properties of a novel anterior trans-pedicular screw artificial vertebral body system (AVBS) with a conventional anterior screw plate system (ASPS) for fixation in the lower cervical spine. Methods A model of the intact cervical spine (C3-C7) was established. AVBS or ASPS constructs were implanted between C4 and C6. The models were loaded in three-dimensional motion. The Von Mises stress distribution in the internal fixators was evaluated, as well as the range of motion (ROM) and facet joint force...
April 7, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28387616/long-term-clinical-and-radiographic-outcomes-of-the-prestige-lp-artificial-cervical-disc-replacement-at-2-levels-results-from-a-prospective-randomized-controlled-clinical-trial
#14
Todd H Lanman, J Kenneth Burkus, Randall G Dryer, Matthew F Gornet, Jeffrey McConnell, Scott D Hodges
OBJECTIVE The aim of this study was to assess long-term clinical safety and effectiveness in patients undergoing anterior cervical surgery using the Prestige LP artificial disc replacement (ADR) prosthesis to treat degenerative cervical spine disease at 2 adjacent levels compared with anterior cervical discectomy and fusion (ACDF). METHODS A prospective, randomized, controlled, multicenter FDA-approved clinical trial was conducted at 30 US centers, comparing the low-profile titanium ceramic composite-based Prestige LP ADR (n = 209) at 2 levels with ACDF (n = 188)...
April 7, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28378073/kinematics-of-cervical-segments-c5-c6-in-axial-rotation-before-and-after-total-disc-arthroplasty
#15
Martin Michael Wachowski, Jan Weiland, Markus Wagner, Riccardo Gezzi, Dietmar Kubein-Meesenburg, Hans Nägerl
PURPOSE: The kinematical properties of C5/C6 segments in axial rotation are evaluated before and after total disc arthroplasty (TDA) with PRESTIGE(®)-and BRYAN(®) Cervical Disc (Medtronic) under flexion/extension as parameters and compared with those of C3/C4. METHODS: Eight human segments were stimulated by triangularly varying, axially directed torque (T z(t)) under compressing static axial preloads. Using a 6D-measuring device with high resolution, the response of segmental motion was characterized by the instantaneous helical axis (IHA)...
April 4, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28377865/regional-variations-in-shear-strength-and-density-of-the-human-thoracic-vertebral-endplate-and-trabecular-bone
#16
Fred Xavier, Julio J Jauregui, Nathan Cornish, Rebecca Jason-Rousseau, Dipal Chatterjee, Gavriel Feuer, Westley Hayes, Bhaveen H Kapadia, John N Carter, Hiroyuki Yoshihara, Subrata Saha
BACKGROUND: Previous studies investigated the overall mechanical strength of the vertebral body; however, limited information is available on the biomechanical properties of different regions within the vertebral endplate and cancellous bone. In addition, the correlation between mechanical strength and various density measurements has not been studied yet. METHODS: Thoracic (T10) vertebrae were harvested from fifteen human cadaveric spines (average age: 77 years old)...
2017: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/28374128/cage-deviation-in-the-subaxial-cervical-spine-in-relation-to-implant-position-in-the-sagittal-plane
#17
Klaus Christian Mende, Sven Oliver Eicker, Friedrich Weber
Subsidence of interbody cages is a frequently observed and relevant complication in anterior cervical discectomy and fusion (ACDF). Only a handful of studies concentrated on the modality of subsidence and its clinical impact. We performed a retrospective analysis of ACDF patients from 2004 to 2010. Numeric analog scale (NAS) score pre-op and post-op, Oswestry Disability Index (ODI) on x-rays, endplate (EP) and cage dimensions, implant position, lordotic/kyphotic subsidence patterns (>5°), and cervical alignment were recorded...
April 4, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28373080/is-a-gradual-reduction-of-stiffness-on-top-of-posterior-instrumentation-possible-with-a-suitable-proximal-implant-a-biomechanical-study
#18
Tobias Lange, Werner Schmoelz, Georg Gosheger, Martin Eichinger, Christian H Heinrichs, Albert Schulze Bövingloh, Tobias L Schulte
BACKGROUND CONTEXT: Proximal junctional kyphosis (PJK) is a challenging complication after rigid posterior instrumentation (RI) of the spine. Several risk factors have been described in literature so far, including the rigidity of the cranial aspect of the implant. PURPOSE: The aim of this biomechanical study was to compare different proximal implants designed to gradually reduce the stiffness between the instrumented and non-instrumented spine. STUDY DESIGN/SETTING: This is a biomechanical study...
March 31, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28370724/clinical-paresthesia-atlas-illustrates-likelihood-of-coverage-based-on-spinal-cord-stimulator-electrode-location
#19
Alexander Taghva, Edward Karst, Paul Underwood
OBJECTIVE: Concordant paresthesia coverage is an independent predictor of pain relief following spinal cord stimulation (SCS). Using aggregate data, our objective is to produce a map of paresthesia coverage as a function of electrode location in SCS. METHODS: This retrospective analysis used x-rays, SCS programming data, and paresthesia coverage maps from the EMPOWER registry of SCS implants for chronic neuropathic pain. Spinal level of dorsal column stimulation was determined by x-ray adjudication and active cathodes in patient programs...
March 28, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28368989/intraoperative-computed-tomography-versus-3d-c-arm-imaging-for-navigated-spinal-instrumentation
#20
Nils Hecht, Hadya Yassin, Marcus Czabanka, Bettina Föhre, Klaus Arden, Thomas Liebig, Peter Vajkoczy
STUDY DESIGN: A prospective case-series study and a retrospective analysis of historical patients for comparison of data. OBJECTIVE: To compare accuracy and limitations of intraoperative computed tomography (iCT)- versus 3D C-arm-based spinal navigation for posterior pedicle screw implantation. SUMMARY OF BACKGROUND DATA: Despite the higher accuracy of navigated compared to non-navigated pedicle screw implantation, it remains a matter of debate whether the use of iCT imaging may further benefit navigated spinal instrumentation compared to more commonly used isocentric 3D C-arm imaging...
March 31, 2017: Spine
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