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https://www.readbyqxmd.com/read/29149204/evaluation-of-osseous-integration-of-titanium-orthopedic-screws-with-novel-sla-treatment-in-porcine-model
#1
Tzu-Hsiang Lin, Hsin-Tai Hu, Hsueh-Chun Wang, Meng-Chian Wu, Shu-Wei Wu, Ming-Long Yeh
The success of many endosseous implants in orthopaedic and dental applications depends on the surface characteristics, as they affect osseous integration. Previous investigations indicated that a novel large-grit sand-blasted and acid-etched (SLA) titanium (denoted as SLAffinity-Ti) implant had better bone integration than that of a comparably shaped implant with a plasma-sprayed titanium surface. The purpose of the present investigation was to create a SLAffinity surface on pedicle screws and trauma screws and to compare it with the surfaces of a sand-blasted-only implant and commercial implants in terms of bone integration...
2017: PloS One
https://www.readbyqxmd.com/read/29145437/assessment-of-the-suitability-of-biodegradable-rods-for-use-in-posterior-lumbar-fusion-an-in-vitro-biomechanical-evaluation-and-finite-element-analysis
#2
Fon-Yih Tsuang, Yueh-Ying Hsieh, Yi-Jie Kuo, Chia-Hsien Chen, Feng-Huei Lin, Chen-Sheng Chen, Chang-Jung Chiang
Interbody fusion with posterior instrumentation is a common method for treating lumbar degenerative disc diseases. However, the high rigidity of the fusion construct may produce abnormal stresses at the adjacent segment and lead to adjacent segment degeneration (ASD). As such, biodegradable implants are becoming more popular for use in orthopaedic surgery. These implants offer sufficient stability for fusion but at a reduced stiffness. Tailored to degrade over a specific timeframe, biodegradable implants could potentially mitigate the drawbacks of conventional stiff constructs and reduce the loading on adjacent segments...
2017: PloS One
https://www.readbyqxmd.com/read/29141662/safety-and-tolerability-of-intradiscal-implantation-of-combined-autologous-adipose-derived-mesenchymal-stem-cells-and-hyaluronic-acid-in-patients-with-chronic-discogenic-low-back-pain-1-year-follow-up-of-a-phase-i-study
#3
Hemant Kumar, Doo-Hoe Ha, Eun-Jong Lee, Jun Hee Park, Jeong Hyun Shim, Tae-Keun Ahn, Kyoung-Tae Kim, Alexander E Ropper, Seil Sohn, Chung-Hun Kim, Devang Kashyap Thakor, Soo-Hong Lee, In-Bo Han
BACKGROUND: Adipose tissue-derived mesenchymal stem cells (AT-MSCs) offer potential as a therapeutic option for chronic discogenic low back pain (LBP) because of their immunomodulatory functions and capacity for cartilage differentiation. The goal of this study was to assess the safety and tolerability of a single intradiscal implantation of combined AT-MSCs and hyaluronic acid (HA) derivative in patients with chronic discogenic LBP. METHODS: We performed a single-arm phase I clinical trial with a 12-month follow-up and enrolled 10 eligible chronic LBP patients...
November 15, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/29134016/a-new-species-of-notodiaptomus-from-the-ecuadorian-andes-copepoda-calanoida-diaptomidae
#4
Miguel Alonso, Edinaldo N Dos Santos-Silva, Damià Jaume
Notodiaptomus cannarensissp. n. is described from a reservoir on the Amazonian slope of the Ecuadorian Andes. The new species is unique among diaptomid calanoid copepods in the display of hypertrophied, symmetrical wing-like extensions at each side of the female composite genital somite. Furthermore, it displays a female urosome reduced to only two somites due to the incorporation of abdominal somites III and IV to the composite genital double-somite, and a male right fifth leg with the outer spine of second exopodal segment recurved and implanted proximally on margin...
2017: ZooKeys
https://www.readbyqxmd.com/read/29129354/surgical-management-and-outcomes-of-patients-with-bone-metastases-in-germ-cell-tumors-a-case-series
#5
Alessandro Nini, Marcus Konieczny, Christian Winter, Achim Lusch, Rüdiger Krauspe, Peter Albers
OBJECTIVE: To report perioperative and oncological outcomes of patients with nodal and bone involvement treated with postchemotherapy retroperitoneal lymph node dissection (PC-RPLND) and simultaneous bone resection (BR). PATIENTS AND METHODS: Between 2008 and 2016, 14 consecutive unselected TC patients with nodal and bone involvement underwent PC-RPLND and BR. Surgery was performed together with orthopedic surgeons. Standard PC-RPLNDs were performed in 4 patients...
November 9, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/29125823/failure-of-an-expandable-cage-plate-cervical-vertebral-body-replacement-case-report-of-a-device-related-complication
#6
Klemens Trieb, Stephan Koch
Instabilities of the cervical spine after complete or incomplete corpectomy may be the result from resection due to stenosis induced myelopathy, tumors, infections or fractures. In this article, we report a 49-year-old female patient after surgical decompression and stabilization at C5/7 with permanent cervicobrachialgia due to cervical stenosis at C5/7. Corpectomy of C6 and stabilization of C5/7 were performed with a combination of cage and plate. At an outpatient control 16 months after reoperation, the patient complained of neck pain, while the control X-ray showed a fracture of the implant...
December 2017: Eklem Hastalıkları Ve Cerrahisi, Joint Diseases & related Surgery
https://www.readbyqxmd.com/read/29113764/effect-of-two-level-pedicle-screw-fixation-with-different-rod-materials-on-lumbar-spine-a-finite-element-study
#7
Jayanta Kumar Biswas, Masud Rana, Santanu Majumder, Santanu Kumar Karmakar, Amit Roychowdhury
BACKGROUND: Pedicle-screw-rod fixation system is very popular surgical remedy for degenerative disc disease. It is important to observe load vs. spinal motion characteristic for better understanding of clinical problems and treatment of spinal instability associated with low-back pain. OBJECTIVE: The objective of this study is to understand the effect [range of motion (ROM) and intervertebral foramen height] of pedicle-screw fixation with three rod materials on lumbar spine under three physiological loading conditions...
November 4, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/29110219/reduction-and-fixation-of-displaced-u-shaped-sacral-fractures-using-lumbopelvic-fixation-technical-recommendations
#8
Stefan Piltz, Bianka Rubenbauer, Wolfgang Böcker, Heiko Trentzsch
PURPOSE: U-shaped sacral fractures are extremely rare injuries that usually occur as a result of falls from considerable heights. Almost all treatment methods described to date aim solely at stabilizing the fracture but do not contribute to supporting the reduction of such fractures. Using existing implants the purpose of this study is to present a surgical technique that facilitates both the reduction and the stabilization of these injuries. The presented technique was evaluated in a series of three cases...
November 6, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29105787/kinematic-behavior-of-a-novel-pedicle-screw-rod-fixation-system-for-the-canine-lumbosacral-joint
#9
Claudia Zindl, Alan S Litsky, Noel Fitzpatrick, Matthew J Allen
OBJECTIVE: To determine the biomechanical behavior of a novel distraction-stabilization system, consisting of an intervertebral distraction bolt, polyaxial screws, and connecting rods, in the canine lumbosacral spine. STUDY DESIGN: Biomechanical study. SAMPLE POPULATION: Cadaveric canine lumbosacral spines (L4-Cd3) (N = 8). METHODS: Cadaveric lumbosacral spines were harvested, stripped of musculature, mounted on a 4-point bending jig, and tested in extension, flexion, and lateral bending using nondestructive compressive axial loads (0-150 N)...
November 6, 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/29105592/biologic-annulus-fibrosus-repair-a-review-of-preclinical-in-vivo-investigations
#10
Stephen Rogers Sloan, Marianne Lintz, Ibrahim Hussain, Roger Härtl, Lawrence J Bonassar
Lower back pain, the leading cause of workplace absences and disability, is often attributed to intervertebral disc (IVD) degeneration in which nucleus pulposus (NP) herniates through lesions in the annulus fibrosus (AF) and impinges on the spinal cord and surrounding nerves. Surgeons remove extruded NP via discectomy when indicated by local/radicular pain supported by radiographic evidence, however current interventions do not alter the underlying disease or seal the AF. The reported rates of recurrent herniation or pain following discectomy cases range from 5-25%, which has pushed spine research in recent years towards annular repair and closure strategies...
November 4, 2017: Tissue Engineering. Part B, Reviews
https://www.readbyqxmd.com/read/29099409/cost-effectiveness-of-primary-and-revision-surgery-for-adult-spinal-deformity
#11
Tina Raman, Suresh K Nayar, Shuiqing Liu, Skolasky L Richard, Khaled M Kebaish
STUDY DESIGN: Retrospective comparative study. OBJECTIVE: The purpose of this study is to compare functional outcomes, hospital resource utilization, and spine-related costs during 2 years in patients who had undergone primary or revision surgery for adult spinal deformity (ASD). SUMMARY OF BACKGROUND DATA: After surgery for ASD, patients may require revision for pseudarthrosis, implant complications, or deformity progression. Data evaluating cost-effectiveness of primary and, in particular, revision surgery, for ASD are sparse...
November 2, 2017: Spine
https://www.readbyqxmd.com/read/29093793/review-of-cortical-bone-trajectory-evidence-of-a-new-technique
#12
REVIEW
Juan Delgado-Fernandez, Maria Ángeles García-Pallero, Guillermo Blasco, Paloma Pulido-Rivas, Rafael G Sola
This article summarizes recent evidence on the cortical bone trajectory (CBT) obtained from published anatomical, biomechanical, and clinical studies. CBT was proposed by Santoni in 2009 as a new trajectory that can improve the fixation of pedicle screws in response to screw loosening in osteoporotic patients. Recently, research interest has been growing with increasing numbers of published series and frequent reports of new applications. We performed an online database search using the terms "cortical bone trajectory," "pedicle screw," "CBT spine," "CBT fixation," "MISS CBT," and "traditional trajectory...
October 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/29093783/the-skipped-segment-screw-construct-an-alternative-to-conventional-lateral-mass-fixation-biomechanical-analysis-in-a-porcine-cervical-spine-model
#13
Kedar Prashant Padhye, Yuvaraja Murugan, Raunak Milton, N Arunai Nambi Raj, Kenny Samuel David
Study Design: Cadaveric biomechanical study. Purpose: We compared the "skipped segment screw" (SSS) construct with the conventional "all segment screw" (ASS) construct for cervical spine fixation in six degrees of freedom in terms of the range of motion (ROM). Overview of Literature: Currently, no clear guidelines are available in the literature for the configuration of lateral mass (LM) screwrod fixation for cervical spine stabilization. Most surgeons tend to insert screws bilaterally at all segments from C3 to C6 with the assumption that implants at every level will provide maximum stability...
October 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/29090368/changes-in-the-midpalatal-and-pterygopalatine-sutures-induced-by-micro-implant-supported-skeletal-expander-analyzed-with-a-novel-3d-method-based-on-cbct-imaging
#14
Daniele Cantarella, Ramon Dominguez-Mompell, Sanjay M Mallya, Christoph Moschik, Hsin Chuan Pan, Joseph Miller, Won Moon
BACKGROUND: Mini-implant-assisted rapid palatal expansion (MARPE) appliances have been developed with the aim to enhance the orthopedic effect induced by rapid maxillary expansion (RME). Maxillary Skeletal Expander (MSE) is a particular type of MARPE appliance characterized by the presence of four mini-implants positioned in the posterior part of the palate with bi-cortical engagement. The aim of the present study is to evaluate the MSE effects on the midpalatal and pterygopalatine sutures in late adolescents, using high-resolution CBCT...
November 1, 2017: Progress in Orthodontics
https://www.readbyqxmd.com/read/29076467/-analysis-of-the-results-of-total-cervical-disc-arthroplasty-using-a-m6-c-prosthesis-a-multicenter-study
#15
V A Byval'tsev, A A Kalinin, I A Stepanov, Yu Ya Pestryakov, V V Shepelev
Cervical spondylosis and intervertebral disc (IVD) degeneration are the most common cause for compression of the spinal cord and/or its roots. Total IVD arthroplasty, as a modern alternative to surgical treatment of IVD degeneration, is gaining popularity in many neurosurgical clinics around the world. Aim - the study aim was to conduct a multicenter analysis of cervical spine arthroplasty with an IVD prosthesis M6-C ('Spinal Kinetics', USA). MATERIAL AND METHODS: The study included 112 patients (77 males and 35 females)...
2017: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
https://www.readbyqxmd.com/read/29059193/safe-corridor-for-the-implantation-of-thoracolumbar-pedicle-screws-in-growing-pigs-a-morphometric-study
#16
Thibaut Cachon, Paul Pillard, Thierry Odent, Claude Carozzo, Eric Viguier
The pig spine is widely used as a large animal model for preclinical research in human medicine to test new spinal implants and surgical procedures. Among them, pedicle screw is one of the most common method of fixation of those implants. However, the pedicle of the porcine vertebra is not as well defined and not as large as the pedicle of the human vertebra. Therefore, the position of the screw should be adapted to the pig and not merely transposed based on the literature on humans. The purpose of this study is to determine the characteristics of the optimum implantation corridors for pedicle screws in the thoracolumbar spine of piglets of different ages using computed tomography (CT) and to determine the size and length of these corridors in pigs of different ages...
2017: PloS One
https://www.readbyqxmd.com/read/29059123/implant-density-at-the-apex-is-more-important-than-overall-implant-density-for-3d-correction-in-thoracic-adolescent-idiopathic-scoliosis-using-rod-derotation-and-en-bloc-vertebral-derotation-technique
#17
Alexandre Delikaris, Xiaoyu Wang, Laure Boyer, A Noelle Larson, Charles G T Ledonio, Carl-Eric Aubin
STUDY DESIGN: Biomechanical analysis of 3D correction and bone-screw forces through numerical simulations of scoliosis instrumentation with different pedicle screw patterns. OBJECTIVE: To analyze the effect of different screw densities and distributions on 3D correction and bone-screw forces in adolescent idiopathic scoliosis (AIS) instrumentation. SUMMARY OF BACKGROUND DATA: Instrumentation constructs with various numbers of pedicle screws and patterns have been proposed for thoracic AIS instrumentation...
October 20, 2017: Spine
https://www.readbyqxmd.com/read/29058045/anterior-cervical-discectomy-and-fusion-review-and-update-for-radiologists
#18
REVIEW
Kimia Khalatbari Kani, Felix S Chew
OBJECTIVES: The goals of this article are to describe the various types of interbody grafts and anterior cervical plating systems, techniques for optimizing evaluation of cervical spine metallic implants on CT and MR imaging, expected appearance and complications of ACDF on postoperative imaging and imaging assessment of fusion. Optimization for optimizing metal induced artifacts. CONCLUSION: Currently, ACDF is the most commonly performed surgical procedure for degenerative cervical spine disease...
October 23, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/29057355/systematic-review-of-3d-printing-in-spinal-surgery-the-current-state-of-play
#19
REVIEW
Ben Wilcox, Ralph J Mobbs, Ai-Min Wu, Kevin Phan
Three-dimensional printing (3DP), also known as "Additive Manufacturing", is a rapidly growing industry, particularly in the area of spinal surgery. Given the complex anatomy of the spine and delicate nature of surrounding structures, 3DP has the potential to aid surgical planning and procedural accuracy. We perform a systematic review of current literature on the applications of 3DP in spinal surgery. Six electronic databases were searched for original published studies reporting cases or outcomes for 3DP surgical models, guides or implants for spinal surgery...
September 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29057346/corpectomy-and-expandable-cage-replacement-versus-third-generation-percutaneous-augmentation-system-in-case-of-vertebra-plana-rationale-and-recommendations
#20
Daniele Vanni, Andrea Pantalone, Vincenzo Magliani, Vincenzo Salini, Pedro Berjano
BACKGROUND: To evaluate the role of third generation percutaneous vertebral augmentation systems (Spine Jack(®)) as alternative to the corpectomies and expandable cages replacement (X-Core(®) Adjustable VBR System) in the treatment of vertebra plana (VP) as complication of the osteoporosis vertebral fracture (OVF). METHODS: Spine Jack(®) is a new device for mechanical kyphoplasty (MK). It is a titanium implant designed to restore the height of the vertebral body in OVF, primary or secondary bone tumors, or traumatic fractures...
September 2017: Journal of Spine Surgery (Hong Kong)
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