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Silica dust and FEV1/FVC

Dirk Taeger, Robert McCunney, Ursula Bailer, Kai Barthel, Ulrich Küpper, Thomas Brüning, Peter Morfeld, Rolf Merget
OBJECTIVES: The aim of this study was to assess the health impact of chronic exposure to synthetic amorphous silica (SAS) on nonmalignant respiratory morbidity. METHODS: We used multiple linear and logistic regression models and Monte Carlo multimodel analyses of two exposure scenarios to evaluate the effect of cumulative exposure to inhalable SAS dust on symptoms, spirometry, and chest films in 462 male workers from five German SAS-producing plants. RESULTS: Exposure to SAS was associated with a reduction in forced vital capacity (FVC) in one of the two exposure scenarios but had no effect on forced expiratory volume in 1 second (FEV1) or FEV1/FVC in either exposure scenario...
April 2016: Journal of Occupational and Environmental Medicine
Chiara Costa, Giorgio Ascenti, Emanuele Scribano, Tommaso D'Angelo, Michele Gaeta, Concettina Fenga, Alfredo Blandino, Silvio Mazziotti
PURPOSE: The aim of this article is to correlate the radiological features of pleuro-pulmonary damage caused by inhalation of pumice (an extrusive volcanic rock classified as a non-fibrous, amorphous, complex silicate) with exposure conditions. MATERIALS AND METHODS: 36 subjects employed in the pumice quarries were evaluated for annual follow-up in a preventive medical surveillance program including spirometry, chest CT lasting from 1999 to 2014. They were only male subjects, mean age 56...
January 2016: La Radiologia Medica
Marwan M Draid, Khaled M Ben-Elhaj, Ashraf M Ali, Kendra K Schmid, Shawn G Gibbs
The purpose of this study was to determine the lung impact from working within the Libyan quarry industry, and if the length of work impacted the degree of degradation. Eighty three workers from eight silica quarries in the Nafusa Mountains of Libya opted to participate. These quarries were working the upper cretaceous geological structure. Eighty-five individuals who lived in Gharyan City with no affiliation to quarry operations participated as controls. Spirometry variables evaluated were Forced Vital Capacity (FVC), Forced Expiratory Volume at 1...
May 2015: International Journal of Environmental Research and Public Health
YounMo Cho, JongIn Lee, Min Choi, WonSeon Choi, Jun-Pyo Myong, Hyoung-Ryoul Kim, Jung-Wan Koo
BACKGROUND: Cigarette smoking is known as the most important risk factor of chronic obstructive pulmonary disease (COPD). However, occupational exposure to other substances can result in COPD. CASE REPORT: A 76-year-old man with occupational exposures to mixtures of silica dust, gas, and fumes for 10 years and with a 25 pack-year smoking history was diagnosed with COPD. His computed tomogram scan revealed some hyperinflation with emphysematous change in both upper lobes...
2015: Annals of Occupational and Environmental Medicine
Raquel Aguirre, Lilian Capone, Gabriela Tabaj, Luciana Molinari, Maria Otaola, Silvia Quadrelli
SESSION TYPE: ILD Global Case Report PostersPRESENTED ON: Tuesday, October 23, 2012 at 01:30 PM - 02:30 PMINTRODUCTION: In 1957 Erasmus published the association between silicosis and the development of scleroderma with lung involvement in gold miners → Erasmus syndrome with an incidence ranging from 12 to 42% according to series publishedCASE PRESENTATION: Male patient 40, with a history of systemic scleroderma (Anti SCl 70 (+), anticentromere (-) diagnosed 2007 with lung involvement from diagnosis of the disease, lung function test: FVC: 3...
October 1, 2012: Chest
Maritta S Jaakkola, Penpatra Sripaiboonkij, Jouni J K Jaakkola
PURPOSE: The aims of this study were to investigate the relations of occupational exposures in tile industry to lung function and to evaluate potential interaction between smoking and tile dust exposure containing silica. METHODS: A cross-sectional study of 232 workers (response rate 100%) in a tile factory and 76 office workers (response rate 73%) from four factories in Thailand was conducted in 2006-2007. Participants answered a questionnaire and performed spirometry...
February 2011: International Archives of Occupational and Environmental Health
R I Ehrlich, J E Myers, J M te Water Naude, M L Thompson, G J Churchyard
OBJECTIVE: To estimate exposure-response relationships between respirable dust, respirable quartz and lung function loss in black South African gold miners. METHODS: 520 mineworkers aged >37 years were enrolled in a cross-sectional study. Gravimetric dust measurements were used to calculate cumulative respirable dust and quartz exposures. Excess lung function loss was defined as predicted minus observed forced expiratory volume in one second (FEV(1)) and forced vital capacity (FVC)...
February 2011: Occupational and Environmental Medicine
Shieh-Ching Yang, Yu-Fan Lin
BACKGROUND: Occupational exposure to coalmine dust consisting of coal particles and free silica eventually results in massive lung fibrosis. However, clinical observations of patients with coal workers' pneumoconiosis (CWP) suggest that airway dysfunction may be a predominant feature in the initial development of the disease. METHODS: Forced expirogram, plethysmographic determination of lung volumes, and measurement of respiratory resistance (Rrs) by the forced oscillation technique at 3, 9, and 18 Hz were conducted in a sample of 71 coal miners with simple pneumoconiosis and 36 healthy subjects...
July 2009: Chang Gung Medical Journal
Bhaskar P Chattopadhyay, Satadal Das, Atin Adhikari, Jane Alam
Grain storage depot workers suffer from different respiratory problems after getting the exposure to storage grain dust. Which is a mixture of pesticides, fungi, silica, bacteria, spores, storage mites, animal hairs, pollens etc. The present study was undertaken to evaluate the fungal spore concentration in summer and winter season as well as the pulmonary function status of the workers; studies are limited in our country. In summer and winter seasons, air sampling was done to measure the airborne fungal spore concentration inside the godowns by Rotorod sampler, UK...
June 2007: Industrial Health
Hiroaki Arakawa, Pierre Alain Gevenois, Yoshiaki Saito, Hisao Shida, Viviane De Maertelaer, Hiroshi Morikubo, Mutsuhisa Fujioka
PURPOSE: To prospectively evaluate if findings on paired inspiratory and expiratory thin-section computed tomographic (CT) scans in patients with silicosis correlate with pulmonary function test results. MATERIALS AND METHODS: Institutional review board approval and patient consent were obtained. Thirty-seven men (mean age, 71 years; range, 53-88 years) with silicosis were included. All patients had undergone inspiratory and expiratory thin-section CT and spirometry...
September 2005: Radiology
Ayşin Sakar, Ece Kaya, Pinar Celik, Nurhan Gencer, Orhan Temel, Nesrin Yaman, Levent Sepit, Cetin Aydin Yildirim, Lale Dağyildizi, Evşen Coşkun, Gönül Dinç, Arzu Yorgancioğlu, Arif Hikmet Cimrin
This study is aimed to evaluate the incidence of silicosis and the relation of it with personal and work-related factors among workers exposed to silica in ceramic factory. Workers were evaluated by respiratory symptoms, physical examination, pulmonary function and radiological findings. Occupational and Enviromental Pulmonary Disease Evaluation Questionnaire of the Turkish Thoracic Society Enviromental and Occupational Pulmonary Diseases Working Group was used. 365 of 626 workers had exposure to silica and the rest 261 were concerned as control group...
2005: Tüberküloz Ve Toraks
A R Bahrami, H Mahjub
The study compared lung function among 322 workers in pottery, ceramic, stone-cutter and stone-grinder factories in the west of the Islamic Republic of Iran. Concentrations of silica particles <2 microm were measured in the ambient air of factories. Forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC) were significantly lower in stone-grinders compared with pottery, ceramic or stone-cutter workers and a control group. No difference in lung function was found in pottery and stone-cutter workers with less than 20 years occupation compared with controls...
May 2003: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
Francesco Forastiere, David F Goldsmith, Alessandra Sperati, Elisabetta Rapiti, Maria Miceli, Fulvio Cavariani, Carlo A Perucci
It is well known that male ceramic workers have elevated risks of chronic silicosis. The objective of this study was to assess whether female ceramic workers also have an increased risk of silicosis and whether these women have decreased lung function related to silica exposure. Ceramic workers from Civitacastellana, Italy, were enrolled in health surveillance during the 1970s. A total of 642 women were under surveillance; a respiratory monitoring program was conducted from 1974 to 1987, with follow-up through 1991 that included annual chest radiography and measurement of lung function...
November 1, 2002: American Journal of Epidemiology
Y H Chen, T N Wu, S H Liou
The purpose of the study was to follow up an earlier observation of pulmonary function among workers employed in firebrick-manufacturing factories. A 2-year follow-up study of pulmonary function among 442 workers in 30 firebrick-manufacturing factories was designed. Excluding 79 workers with a history of other occupational dust exposure, changes in pulmonary function of 291 firebrick workers were compared with pulmonary function in 72 control subjects over a period of 2 years. Baseline pulmonary function values (i...
November 2001: Journal of Occupational and Environmental Medicine
X Wang, E Yano
BACKGROUND: It has been established that occupational exposure to silica dust may cause significant impairment of pulmonary function. To compare the contribution of silicosis and emphysema to pulmonary dysfunction, radiographic signs of silicosis and emphysema in silica exposed workers were analyzed. METHODS: Two hundred and twenty workers exposed to silica working in a Chinese refractory plant were selected as study subjects. Their findings of silicosis and emphysematous changes on radiograph were classified and evaluated...
August 1999: American Journal of Industrial Medicine
P Harber, J Dahlgren, W Bunn, J Lockey, G Chase
Diatomaceous earth is a noncrystalline form of silica; in processing, calcining leads to formation of cristobalite, a form of crystalline silica. Four hundred ninety-two currently employed diatomaceous earth workers in a large mine and processing facility had chest radiographs performed and interpreted by the International Labour Office (ILO) system. Two hundred sixty-seven subjects underwent spirometry testing. Exposure indices for total dust (largely diatomaceous earth) and cristobalite were reconstructed for each individual based upon personnel records...
January 1998: Journal of Occupational and Environmental Medicine
X Wang, E Yano, K Nonaka, M Wang, Z Wang
We conducted a comparative study of pulmonary dysfunction among workers who were exposed to silica, asbestos, or coalmine dust. The results showed that all three groups of dust-exposed workers, even those without radiographic signs of pneumoconiosis, had decreased spirometric parameters and diffusing capacity (DLco) in both nonsmokers and smokers. Pulmonary function was further decreased when pneumoconioses were present in the three groups. In accord with increasing radiographic categories, pulmonary function in the workers with either silicosis or asbestosis was even lower, whereas in those with coal workers' pneumoconiosis (CWP), it changed relatively little...
May 1997: American Journal of Industrial Medicine
D Talini, P L Paggiaro, F Falaschi, L Battolla, M Carrara, M Petrozzino, E Begliomini, C Bartolozzi, C Giuntini
OBJECTIVES: To compare the usefulness of high resolution computed tomography (HRCT) with chest radiography (CR) in the diagnosis and assessment of severity of silicosis. METHODS: 27 workers exposed to silica underwent CR, HRCT, and pulmonary function tests. Two experienced readers independently evaluated CR by International Labour Office classification, and grouped the results into four categories. HRCT categories of nodule profusion and the extent of emphysema were graded on a four point scale; in 20 subjects the percentage distribution of lung densities were measured by HRCT...
April 1995: Occupational and Environmental Medicine
R Bégin, R Filion, G Ostiguy
It has been established that coal pneumoconiosis and confluent silicosis are associated with emphysematous changes in the lungs. In the present study, we addressed the concept of emphysema in simple silicosis and asbestosis and in workers exposed to these minerals without the pneumoconiosis. The study was done on 207 consecutive workers evaluated for possible pneumoconiosis at Québec Workman Compensation Board, who had a radiographic reading of pneumoconiosis in the category 0 or 1 of the ILO scale, and in 5 control subjects...
September 1995: Chest
D H Wegman, J M Peters, M G Boundy, T J Smith
Miners and millers of talc ore, free from asbestos and silica, were examined for respiratory effects. A study of 116 subjects included the modified British Medical Research Council respiratory symptom questionnaire, simple spirometry, chest radiography, and limited examination of the chest. A one-year follow-up evaluation was performed on 103 subjects. Of the 12 subjects whose chest radiographs showed small round or irregular opacities (perfusion 1/0 or greater), five had never smoked cigarettes. Pulmonary function values at the time of the initial study were less than predicted and the rates of loss of FEV1 and FVC greater than expected...
August 1982: British Journal of Industrial Medicine
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