keyword
https://read.qxmd.com/read/38537147/first-report-of-phytophthora-niederhauserii-causing-root-rot-of-carob-tree-ceratonia-siliqua-l-in-spain
#1
JOURNAL ARTICLE
Carolina Francia, Josep Armengol, Paloma Abad-Campos
Carob tree (Ceratonia siliqua L.) is a crop native to the Mediterranean Basin mainly being used as livestock feed, in pharmaceutical industry, and also a valuable source of human food due to the high dietary fibre and sugar contents. In January 2023, one-year-old 'Duraio' carob trees grafted on 'Rojal' rootstock on pots showing dark brown to necrotic lesions on the secondary roots, decline symptoms and leading to the death of some plants, were detected in a nursery located at the Valencian Community region in Spain...
March 27, 2024: Plant Disease
https://read.qxmd.com/read/38537071/metabolic-tumor-burden-as-a-prognostic-indicator-after-neoadjuvant-chemotherapy-in-pancreatic-cancer
#2
JOURNAL ARTICLE
Woohyung Lee, Minyoung Oh, Jae Seung Kim, Minkyu Sung, Kwangpyo Hong, Bong Jun Kwak, Yejong Park, Eunsung Jun, Ki Byung Song, Dae Wook Hwang, Jae Hoon Lee, Changhoon Yoo, Kyu-Pyo Kim, Inkeun Park, Jae Ho Jeong, Heung-Moon Chang, Baek-Yeol Ryoo, Jung Bok Lee, Song Cheol Kim
BACKGROUND: There is no standardized assessment for evaluating response although neoadjuvant chemotherapy (NAT) is widely accepted for borderline resectable or locally advanced pancreatic cancer (BRPC or LAPC). This study was aimed to evaluate NAT response using positron emission tomography with 2-deoxy-2-[fluorine-18]fluoro-D-glucose (18F-FDG-PET/CT) parameters alongside carbohydrate antigen (CA) 19-9 levels. METHODS: Patients who underwent surgery after NAT for BRPC and LAPC between 2017 and 2021 were identified...
April 3, 2024: International Journal of Surgery
https://read.qxmd.com/read/38536932/crif1-deficiency-induces-foxp3-low-inflammatory-non-suppressive-regulatory-t-cells-thereby-promoting-antitumor-immunity
#3
JOURNAL ARTICLE
Sangsin Lee, Seung Geun Song, Gwanghun Kim, Sehui Kim, Hyun Jung Yoo, Jaemoon Koh, Ye-Ji Kim, Jingwen Tian, Eunji Cho, Youn Soo Choi, Sunghoe Chang, Hyun Mu Shin, Kyeong Cheon Jung, Ji Hoon Kim, Tae Min Kim, Yoon Kyung Jeon, Hye Young Kim, Minho Shong, Ji Hyung Kim, Doo Hyun Chung
Recently identified human FOXP3low CD45RA- inflammatory non-suppressive (INS) cells produce proinflammatory cytokines, exhibit reduced suppressiveness, and promote antitumor immunity unlike conventional regulatory T cells (Tregs ). In spite of their implication in tumors, the mechanism for generation of FOXP3low CD45RA- INS cells in vivo is unclear. We showed that the FOXP3low CD45RA- cells in human tumors demonstrate attenuated expression of CRIF1, a vital mitochondrial regulator. Mice with CRIF1 deficiency in Tregs bore Foxp3low INS-Tregs with mitochondrial dysfunction and metabolic reprograming...
March 29, 2024: Science Advances
https://read.qxmd.com/read/38536909/atom-by-atom-imaging-of-moir%C3%A3-transformations-in-2d-transition-metal-dichalcogenides
#4
JOURNAL ARTICLE
Yichao Zhang, Ji-Hwan Baek, Chia-Hao Lee, Yeonjoon Jung, Seong Chul Hong, Gillian Nolan, Kenji Watanabe, Takashi Taniguchi, Gwan-Hyoung Lee, Pinshane Y Huang
Understanding the atomic-scale mechanisms that govern the structure of interfaces is critical across materials systems but particularly so for two-dimensional (2D) moiré materials. Here, we image, atom-by-atom, the thermally induced structural evolution of twisted bilayer transition metal dichalcogenides using in situ transmission electron microscopy. We observe low-temperature, local conversion of moiré superlattice into nanoscale aligned domains. Unexpectedly, this process occurs by nucleating a new grain within one monolayer, whose crystal orientation is templated by the other...
March 29, 2024: Science Advances
https://read.qxmd.com/read/38536087/-peptostreptococcus-equinus-sp-nov-isolated-from-horse-faeces
#5
JOURNAL ARTICLE
Hye Su Jung, Jeong Ui Yun, Mi-Ja Jung, Hye Seon Song, Yeon Bee Kim, Yujin Kim, Min Ji Lee, Jisu Lee, Che Ok Jeon, Seong Woon Roh, Tae Woong Whon, Joon-Gyu Kim, Se Hee Lee
A Gram-stain-positive, non-spore-forming, and obligate anaerobic bacteria designated strain CBA3647T was isolated from a horse faecal sample in Jeju, Republic of Korea. Phylogenetic analysis based on 16S rRNA gene sequences showed that strain CBA3647T formed a distinct phyletic lineage from closely related species within the genus Peptostreptococcus . Based on comparative analysis of 16S rRNA gene sequences, Peptostreptococcus anaerobius ATCC 27337T is most closely related to strain CBA3647T with a 16S rRNA gene similarity of 98...
March 2024: International Journal of Systematic and Evolutionary Microbiology
https://read.qxmd.com/read/38535908/associations-between-urinary-mercury-cadmium-concentrations-and-anthropometric-features-in-korean-children
#6
JOURNAL ARTICLE
Min Won Shin, Hyo-Bin Kim, Ahreum Kwon, Mi Jung Park, Shin-Hye Kim
Investigating the impact of urinary mercury and cadmium on anthropometric parameters in Korean children is crucial amid growing concerns about heavy metal exposure and childhood growth. Using data from the Korean National Environmental Health Survey (2015-2017), we assessed age- and sex-specific associations of urinary mercury and cadmium with height and body mass index (BMI) z-scores in 1458 children aged 3-5 (n = 571) and 6-11 years (n = 887). Overall, 5.0% had stunted height (3-5 years: 6.9%, 6-11 years: 3...
February 24, 2024: Toxics
https://read.qxmd.com/read/38535651/energy-storage-performance-of-electrode-materials-derived-from-manganese-metal-organic-frameworks
#7
JOURNAL ARTICLE
Gyeongbeom Ryoo, Seon Kyung Kim, Do Kyung Lee, Young-Jin Kim, Yoon Soo Han, Kyung-Hye Jung
Metal-organic frameworks (MOFs) are porous materials assembled using metal and organic linkers, showing a high specific surface area and a tunable pore size. Large portions of metal open sites in MOFs can be exposed to electrolyte ions, meaning they have high potential to be used as electrode materials in energy storage devices such as supercapacitors. Also, they can be easily converted into porous metal oxides by heat treatment. In this study, we obtained high energy storage performance by preparing electrode materials through applying heat treatment to manganese MOFs (Mn-MOFs) under air...
March 11, 2024: Nanomaterials
https://read.qxmd.com/read/38535468/induction-of-autophagy-by-extract-from-corydalis-heterocarpa-for-skin-anti-aging
#8
JOURNAL ARTICLE
Kyeong Eun Yang, Soo-Bin Nam, Ga-Eun Lee, Gabsik Yang, Mee-Hyun Lee, Geul Bang, Jung Hoon Choi, Yong-Yeon Cho, Cheol-Jung Lee
The extracts of Corydalis heterocarpa , a salt-tolerant plant, exhibit diverse physiological properties, including anti-inflammatory, anticancer, and antiadipogenic effects. However, the anti-aging effects of C. heterocarpa extract (CHE) on human skin cells have not yet been investigated. In the present study, we determined that CHE inhibited senescence-associated β-galactosidase (SA-β-gal)-stained senescent human dermal fibroblasts (HDFs). Furthermore, CHE markedly suppressed the expression of major regulatory proteins involved in senescence, including p53, p21, and caveolin-1...
March 8, 2024: Marine Drugs
https://read.qxmd.com/read/38535449/the-role-of-sargahydroquinoic-acid-and-sargachromenol-in-the-anti-inflammatory-effect-of-sargassum-yezoense
#9
JOURNAL ARTICLE
Yena Park, Lei Cao, Suhyeon Baek, Seungjin Jeong, Hyun Jung Yun, Mi-Bo Kim, Sang Gil Lee
The anti-inflammatory effect of the ethanol extract of Sargassum yezoense and its fractions were investigated in this study. The ethanol extract exhibited a strong anti-inflammatory effect on lipopolysaccharide-stimulated RAW 264.7 macrophages and effectively suppressed the M1 polarization of murine bone-marrow-derived macrophages stimulated by lipopolysaccharides and IFN-γ (interferon-gamma). Through a liquid-liquid extraction process, five fractions (n-hexane, chloroform, ethyl acetate, butanol, and aqueous) were acquired...
February 26, 2024: Marine Drugs
https://read.qxmd.com/read/38535337/chemical-composition-and-nutritional-value-of-royal-jelly-samples-obtained-from-honey-bee-apis-mellifera-hives-fed-on-oak-and-rapeseed-pollen-patties
#10
JOURNAL ARTICLE
Sampat Ghosh, Chuleui Jung
Young workers, i.e., nurse honey bees, synthesize and secrete royal jelly to feed the brood and queen. Since royal jelly is a protein-rich substance, the quality of royal jelly may be influenced by the consumption of feed with varying protein content. We tested whether honey bee ( Apis mellifera ) colonies compensates for the nutritional quality to produce royal jelly by feeding different pollen patties made of oak or rapeseed pollen. After harvesting royal jelly, we examined the chemical composition including proximate nutrients, amino acids, proteins, fatty acids, and minerals of royal jelly samples obtained from two treatments...
February 21, 2024: Insects
https://read.qxmd.com/read/38535105/echocardiographic-fluoroscopic-fusion-imaging-improves-interventionalists-learning-curve-for-percutaneous-left-atrial-appendage-closure-initial-single-center-retrospective-observations
#11
JOURNAL ARTICLE
Dominika Kanschik, Houtan Heidari, Kathrin Klein, Amin Polzin, Verena Veulemans, Jürgen Leick, Malte Kelm, Christian Jung, Tobias Zeus, Shazia Afzal
Due to the complex and variable anatomy of the left atrial appendage, percutaneous left atrial appendage closure (LAAC) can be challenging. In this study, we investigated the impact of fusion imaging (FI) on the LAAC learning curve of two interventionalists. The first interventionalist (IC 1) was initially trained without FI and continued his training with FI. The second interventionalist (IC 2) performed all procedures with FI. We compared the first 36 procedures without FI of IC 1 (group 1) with his next 36 interventions with FI (group 2)...
February 29, 2024: Journal of Cardiovascular Development and Disease
https://read.qxmd.com/read/38534984/clinical-research-into-central-nervous-system-inflammatory-demyelinating-diseases-related-to-covid-19-vaccines
#12
JOURNAL ARTICLE
Mei-Yun Cheng, Hsuan-Chen Ho, Jung-Lung Hsu, Yi Wang, Linyi Chen, Siew-Na Lim, Ming-Feng Liao, Long-Sun Ro
Various vaccines have been developed in response to the SARS-CoV-2 pandemic, and the safety of vaccines has become an important issue. COVID-19 vaccine-related central nervous system inflammatory demyelinating diseases (CNS IDDs) have been reported recently. We present one case of AstraZeneca vaccine-related myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease and a literature review of another 78 patients published from January 2020 to October 2022. Patients were divided into three vaccine types (viral vector, mRNA, and inactivated vaccines) for further analyses...
March 20, 2024: Diseases (Basel)
https://read.qxmd.com/read/38534731/dual-immunoglobulin-domain-containing-cell-adhesion-molecule-increases-early-in-renal-tubular-cell-injury-and-plays-anti-inflammatory-role
#13
JOURNAL ARTICLE
Jin Han, Ju-Min Yook, Se-Hyun Oh, Yu Kyung Chung, Hee-Yeon Jung, Ji-Young Choi, Jang-Hee Cho, Sun-Hee Park, Chan-Duck Kim, Yong-Lim Kim, Seungwoo Han, Jeong-Hoon Lim
Dual immunoglobulin domain-containing cell adhesion molecule (DICAM) is a type I transmembrane protein that presents in various cells including renal tubular cells. This study evaluated the expression and protective role of DICAM in renal tubular cell injury. HK-2 cells were incubated and treated with lipopolysaccharide (LPS, 30 μg/mL) or hydrogen peroxide (H2 O2 , 100 μM) for 24 h. To investigate the effect of the gene silencing of DICAM, small interfering RNA of DICAM was used. Additionally, to explain its role in cellular response to injury, DICAM was overexpressed using an adenoviral vector...
February 26, 2024: Current Issues in Molecular Biology
https://read.qxmd.com/read/38534693/intrapulmonary-and-systemic-pharmacokinetics-of-colistin-following-nebulization-of-low-dose-colistimethate-sodium-in-patients-with-ventilator-associated-pneumonia-caused-by-carbapenem-resistant-acinetobacter-baumannii
#14
JOURNAL ARTICLE
Dong-Hwan Lee, Shin-Young Kim, Yong-Kyun Kim, So-Young Jung, Ji-Hoon Jang, Hang-Jea Jang, Jae-Ha Lee
Colistimethate sodium (CMS) nebulization is associated with reduced systemic toxicity compared to intravenous injection, with potentially enhanced clinical efficacy. This study aimed to assess the pharmacokinetic (PK) properties of colistin during low-dose CMS nebulization in patients with ventilator-associated pneumonia (VAP) caused by carbapenem-resistant Acinetobacter baumannii . A nonlinear mixed-effects modeling approach was applied to develop population PK models for colistin in both epithelial lining fluid (ELF) and plasma...
March 14, 2024: Antibiotics
https://read.qxmd.com/read/38534600/fibrin-based-hydrogels-with-reactive-amphiphilic-copolymers-for-mechanical-adjustments-allow-for-capillary-formation-in-2d-and-3d-environments
#15
JOURNAL ARTICLE
Svenja Wein, Carina Schemmer, Miriam Aischa Al Enezy-Ulbrich, Shannon Anna Jung, Stephan Rütten, Mark Kühnel, Danny Jonigk, Wilhelm Jahnen-Dechent, Andrij Pich, Sabine Neuss
This study focuses on enhancing controllable fibrin-based hydrogels for tissue engineering, addressing existing weaknesses. By integrating a novel copolymer, we improved the foundation for cell-based angiogenesis with adaptable structural features. Tissue engineering often faces challenges like waste disposal and nutrient supply beyond the 200 µm diffusion limit. Angiogenesis breaks through this limitation, allowing the construction of larger constructs. Our innovative scaffold combination significantly boosts angiogenesis, resulting in longer branches and more capillary network junctions...
March 6, 2024: Gels
https://read.qxmd.com/read/38534522/does-deep-squat-quality-affect-the-propulsion-of-baseball-throwing
#16
JOURNAL ARTICLE
Wei-Hsuan Lin, Tsung-Yu Huang, Shu-Wei Chen, Joseph Hamill, Jung-Tang Kung, Wen-Tzu Tang
This study investigates the influence of the quality of the "deep squat" movement, adapted from the Functional Movement Screen (FMS) system, on the lower extremity movement pattern during baseball throwing, and its potential impact on throwing performance and propulsion efficiency. Twenty-two baseball players were recruited and categorized into two groups: 13 in the high-score squat group (HSS) and 9 in the low-score squat group (LSS), based on their deep squat screening results. This research explored disparities in ball velocity, propulsion efficiency, propulsion ground reaction force (GRF) characteristics, and throwing kinematics between these two groups...
March 2, 2024: Bioengineering
https://read.qxmd.com/read/38534515/managing-vascular-pedicle-exposure-in-free-tissue-transfer-using-a-reprocessed-micronized-dermal-substitute-in-lower-extremity-reconstructions
#17
JOURNAL ARTICLE
Daheui Kim, Jun Hyeok Lee, Min Suk Park, Ma Rhip Ahn, Daiwon Jun, Jung Ho Lee
Lower extremity reconstruction is challenging because of its intricate anatomy and dynamic biomechanics. Although microsurgical free tissue transfer offers pivotal solutions to limited local tissue availability, vascular pedicle exposure after free tissue transfer is common. We evaluated a novel method of managing pedicle exposure after free tissue transfer using a reprocessed micronized dermal substitute. Ten patients who underwent lower-extremity reconstruction using free tissue transfer and micronized dermal substitute between January and December 2023 were retrospectively reviewed...
February 28, 2024: Bioengineering
https://read.qxmd.com/read/38534485/reliable-off-resonance-correction-in-high-field-cardiac-mri-using-autonomous-cardiac-b-0-segmentation-with-dual-modality-deep-neural-networks
#18
JOURNAL ARTICLE
Xinqi Li, Yuheng Huang, Archana Malagi, Chia-Chi Yang, Ghazal Yoosefian, Li-Ting Huang, Eric Tang, Chang Gao, Fei Han, Xiaoming Bi, Min-Chi Ku, Hsin-Jung Yang, Hui Han
B0 field inhomogeneity is a long-lasting issue for Cardiac MRI (CMR) in high-field (3T and above) scanners. The inhomogeneous B0 fields can lead to corrupted image quality, prolonged scan time, and false diagnosis. B0 shimming is the most straightforward way to improve the B0 homogeneity. However, today's standard cardiac shimming protocol requires manual selection of a shim volume, which often falsely includes regions with large B0 deviation (e.g., liver, fat, and chest wall). The flawed shim field compromises the reliability of high-field CMR protocols, which significantly reduces the scan efficiency and hinders its wider clinical adoption...
February 23, 2024: Bioengineering
https://read.qxmd.com/read/38534236/one-step-detection-of-vancomycin-in-whole-blood-using-the-lateral-flow-immunoassay
#19
JOURNAL ARTICLE
Yugyung Jung, Seonjong Kim, Min-Gon Kim, Young-Eun Lee, Myung-Geun Shin, Sung Yang
Vancomycin (VAN) is an effective antibiotic against Gram-positive bacteria and the first-line therapy to prevent and treat methicillin-resistant Staphylococcus aureus (MRSA) and severe infections. However, low concentrations of VAN can result in resistant strains. High doses of VAN can cause nephrotoxicity and ototoxicity; thus, VAN is a representative drug for which drug monitoring is recommended. Several methods have been proposed to detect VAN. Among them, lateral flow immunoassays (LFIAs) have advantages, such as simple and user-friendly operation, low sample volume requirement, and cost effectiveness...
February 29, 2024: Biosensors
https://read.qxmd.com/read/38534086/unstable-vancouver-b1-periprosthetic-femoral-fracture-fixation-a-biomechanical-comparison-between-a-novel-c-shaped-memory-alloy-implant-and-cerclage-wiring
#20
JOURNAL ARTICLE
Seog-Hyun Oh, Yu-Sung Suh, Emmanuel Eghan-Acquah, Kollerov Mikhail Yurevich, Sung-Hun Won, Min Jung Baek, Sung-Jae Lee, Sung-Woo Choi
BACKGROUND: To compare the biomechanical stability of a novel, C-shaped nickel-titanium shape memory alloy (SMA) implant (C-clip) with traditional cerclage wiring in the fixation of a Vancouver B1 (VB1) periprosthetic femoral fracture (PFF). METHODS: In total, 18 synthetic femoral fracture models were constructed to obtain unstable VB1 fracture with an oblique fracture line 8 cm below the lesser trochanter. For each model, the distal portion was repaired using a 10-hole locking plate and four distal bi-cortical screws...
March 2024: Journal of International Medical Research
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