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https://www.readbyqxmd.com/read/28549378/multi-layer-snse-nanoflake-field-effect-transistors-with-low-resistance-au-ohmic-contacts
#1
Sang-Hyeok Cho, Kwanghee Cho, No-Won Park, Soonyong Park, Jung-Hyuk Koh, Sang-Kwon Lee
We report p-type tin monoselenide (SnSe) single crystals, grown in double-sealed quartz ampoules using a modified Bridgman technique at 920 °C. X-ray powder diffraction (XRD) and energy dispersive X-ray spectroscopy (EDX) measurements clearly confirm that the grown SnSe consists of single-crystal SnSe. Electrical transport of multi-layer SnSe nanoflakes, which were prepared by exfoliation from bulk single crystals, was conducted using back-gated field-effect transistor (FET) structures with Au and Ti contacts on SiO2/Si substrates, revealing that multi-layer SnSe nanoflakes exhibit p-type semiconductor characteristics owing to the Sn vacancies on the surfaces of SnSe nanoflakes...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28549296/formation-mechanism-of-%C3%AE-lactalabumin-oleic-acid-complex-characterized-by-2d-correlation-analysis
#2
Yeonju Park, Yeseul Kim, Yujeong Park, Sila Jin, Hoon Hwang, Young Mee Jung
Partially unfolded α-lactalbumin (ALA) forms a complex with oleic acid (OA) that exhibits cytotoxic activity. In this study, for the first time, the pH-induced formation mechanism for ALA/OA complexes with two different molar ratios was investigated at the molecular level. For a deeper understanding of the formation mechanism of the two different ALA/OA complexes with decreasing pH, principal component analysis (PCA) and two-dimensional (2D) correlation spectroscopy were used to examine the pH-dependent IR spectra of ALA/OA complexes...
May 17, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28549289/identifying-the-source-of-zn-in-soils-around-a-zn-smelter-using-pb-isotope-ratios-and-mineralogical-analysis
#3
Soo-Kyung Jeon, Man Jae Kwon, Jung-Seok Yang, Seunghak Lee
The contribution by anthropogenic sources to abnormally high Zn concentrations in soils with naturally abundant Zn was investigated at a contaminated site surrounding a Zn smelter in eastern Korea. Nineteen soil samples were collected within a 2km radius of the smelter, and analyzed for metal concentrations and Pb isotope ratios using an inductively coupled plasma-optical emission spectrometer and -mass spectrometer, respectively. Higher Zn concentrations in locations closer to the smelter implied that the smelter was the source of the Zn pollution...
May 23, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28549070/the-atherogenic-index-of-plasma-and-the-risk-of-mortality-in-incident-dialysis-patients-results-from-a-nationwide-prospective-cohort-in-korea
#4
Mi Jung Lee, Jung Tak Park, Seung Hyeok Han, Yong-Lim Kim, Yon Su Kim, Chul Woo Yang, Nam-Ho Kim, Shin-Wook Kang, Hyung Jong Kim, Tae-Hyun Yoo
BACKGROUND: The atherogenic index of plasma (AIP), which is the logarithmic ratio of triglyceride (TG) to high-density lipoprotein cholesterol (HDL-C), had a linear relationship with clinical outcomes in the general population. However, the association of each lipid profile, TG and HDL-C, with survival was not straightforward in dialysis patients. This non-linear association led us to further investigate the prognostic impact of the AIP in these patients. METHODS: From a nationwide prospective cohort, 1,174 incident dialysis patients were included...
2017: PloS One
https://www.readbyqxmd.com/read/28549014/robot-assisted-versus-laparoscopic-surgery-for-rectal-cancer-a-phase-ii-open-label-prospective-randomized-controlled-trial
#5
Min Jung Kim, Sung Chan Park, Ji Won Park, Hee Jin Chang, Dae Yong Kim, Byung-Ho Nam, Dae Kyung Sohn, Jae Hwan Oh
OBJECTIVE: The phase II randomized controlled trial aimed to compare the outcomes of robot-assisted surgery with those of laparoscopic surgery in the patients with rectal cancer. BACKGROUND: The feasibility of robot-assisted surgery over laparoscopic surgery for rectal cancer has not been established yet. METHODS: Between February 21, 2012 and March 11, 2015, patients with rectal cancer (cT1-3NxM0) were enrolled. Patients were randomized 1:1 to either robot-assisted or laparoscopic surgery, and stratified per sex and administration of preoperative chemoradiotherapy...
May 25, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28549002/clinical-significance-of-histogram-parameters-on-elastography-in-patients-with-papillary-thyroid-microcarcinomas
#6
Hee Yeun Yoon, Ji Hye Lee, Young Eun Kim, Eun-Kyung Kim, Hee Jung Moon, Jung Hyun Yoon, Vivian Y Park, Jin Young Kwak
OBJECTIVE: The purpose of our study was to determine objective histogram parameters on elastography that could predict poor prognosis factors of conventional papillary thyroid microcarcinomas (PTMCs). METHODS: From September to November in 2012, 79 patients with a diagnosis of PTMCs were included. Mean values of clinicopathologic variables and histogram parameters on elastography were compared between groups with or without poor prognostic factors using the Student t test, χ test, or Fisher exact test...
May 25, 2017: Ultrasound Quarterly
https://www.readbyqxmd.com/read/28548964/the-value-of-phosphohistone-h3-as-a-proliferation-marker-for-evaluating-invasive-breast-cancers-a-comparative-study-with-ki67
#7
Ji-Ye Kim, Hyang Sook Jeong, Taek Chung, Moonsik Kim, Ji Hee Lee, Woo Hee Jung, Ja Seung Koo
BACKGROUND: Established measurements of proliferation in breast cancer are Ki67 and mitotic-activity-index (MAI), with problems in reproducibility and prognostic accuracy. Phosphohistone H3 (PHH3), a relatively novel IHC marker is specific for mitosis with good reproducibility. We hypothesized that PHH3 would be more reproducible and better represent proliferation than Ki67. RESULTS: PHH3 identified easily-missed mitosis by MAI, as demonstrated by upgrading M grade at diagnosis (n = 29/218, evenly distributed)...
May 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/28548948/effect-of-renal-embolization-in-patients-with-synchronous-metastatic-renal-cell-carcinoma-a-retrospective-comparison-of-cytoreductive-nephrectomy-and-systemic-medical-therapy
#8
Sung Han Kim, Jung Kwon Kim, Boram Park, Jungnam Joo, Jae Young Joung, Ho Kyung Seo, Kang Hyun Lee, Jinsoo Chung
OBJECTIVE: To compare survival outcomes for renal embolization (RE) to cytoreductive nephrectomy (CN) and no primary renal treatment (NT) among patients with synchronous metastatic renal cell carcinoma (mRCC) treated using either targeted therapy (TT) or immunotherapy (IT). RESULTS: The median follow-up duration was 81.3 months, with a duration of first-line treatment of 3.5 months. Among the 211 patients, the median PFS and OS were 4.4 and 10.6 months. Specifically for patients receiving TT (124 patients), the PFS and OS were 5...
May 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28548930/comparison-of-treatment-outcome-between-living-donor-liver-transplantation-and-sorafenib-for-patients-with-hepatocellular-carcinoma-beyond-the-milan-criteria
#9
Yuri Cho, Jeong-Hoon Lee, Dong Hyeon Lee, Eun Ju Cho, Su Jong Yu, Nam-Joon Yi, Kwang-Woong Lee, Yoon Jun Kim, Jung-Hwan Yoon, Kyung-Suk Suh
For patients with advanced hepatocellular carcinoma (HCC), sorafenib is the only systemic treatment recommended by international guidelines. We recently reported that HCC patients with a low MoRAL (model to predict tumor recurrence after LDLT) score (≤ 314.8) have excellent treatment outcomes after living-donor liver transplantation (LDLT), even though they are beyond the Milan criteria. In the present study, we investigated whether LDLT offers a better treatment outcome than sorafenib for patients with HCC beyond the Milan criteria according to the MoRAL score...
May 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/28548547/facing-a-health-threat-in-a-complex-information-environment-a-national-representative-survey-examining-american-adults-behavioral-responses-to-the-2009-2010-a-h1n1-pandemic
#10
Leesa Lin, Rachel F McCloud, Minsoo Jung, Kasisomayajula Viswanath
BACKGROUND: Recent A(H1N1) studies suggest that intrapersonal and interpersonal factors may exert influence on people's preventive behaviors for avoiding the flu during pandemics. AIMS: Nonpharmaceutical interventions (NPIs) and vaccinations play key roles in containing disease transmission during a pandemic. We examined how intrapersonal and interpersonal factors influenced adoption of NPIs and vaccine uptake during the A(H1N1) pandemic of 2009. METHOD: The data come from a nationally representative sample survey of 1,569 American adults...
May 1, 2017: Health Education & Behavior: the Official Publication of the Society for Public Health Education
https://www.readbyqxmd.com/read/28548306/zanthoxylum-avicennae-extract-enhances-gsk-3%C3%AE-to-attenuate-%C3%AE-catenin-via-phosphatase-2a-to-block-metastatic-effects-of-ha22t-cells-and-hepatocellular-carcinoma-xenografted-nude-mice
#11
Hsi-Chin Wu, Ing-Shiow Lay, Marthandam Asokan Shibu, Tsung-Jung Ho, Shiu-Min Cheng, Chih-Hao Lin, Tran Duc Dung, Long-Bin Jeng, Vijaya Padma Viswanadha, Chih-Yang Huang
Hepatocellular carcinoma (HCC) metastasis is often associated with the activation of Wnt/β-catenin signaling pathway. Zanthoxylum avicennae (Ying Bu Bo, YBB), a traditional herb with hepatoprotective effect, has been proven to inhibit human HCC in in vivo models however, the in vitro and in vivo effect of YBB on tumor metastasis is not clear yet. To determine whether YBB could inhibit HA22T human HCC cell by acting on β-catenin metastatic signaling in vitro and in vivo, HA22T cells were treated with different concentrations of YBB extracts (YBBE) and analyzed by Immunofluorescence staining assay, western blot analysis, siRNA mediated gene knock-down assays and co-immunoprecipitation assay...
May 26, 2017: Environmental Toxicology
https://www.readbyqxmd.com/read/28548087/the-distinct-metabolic-phenotype-of-lung-squamous-cell-carcinoma-defines-selective-vulnerability-to-glycolytic-inhibition
#12
Justin Goodwin, Michael L Neugent, Shin Yup Lee, Joshua H Choe, Hyunsung Choi, Dana M R Jenkins, Robin J Ruthenborg, Maddox W Robinson, Ji Yun Jeong, Masaki Wake, Hajime Abe, Norihiko Takeda, Hiroko Endo, Masahiro Inoue, Zhenyu Xuan, Hyuntae Yoo, Min Chen, Jung-Mo Ahn, John D Minna, Kristi L Helke, Pankaj K Singh, David B Shackelford, Jung-Whan Kim
Adenocarcinoma (ADC) and squamous cell carcinoma (SqCC) are the two predominant subtypes of non-small cell lung cancer (NSCLC) and are distinct in their histological, molecular and clinical presentation. However, metabolic signatures specific to individual NSCLC subtypes remain unknown. Here, we perform an integrative analysis of human NSCLC tumour samples, patient-derived xenografts, murine model of NSCLC, NSCLC cell lines and The Cancer Genome Atlas (TCGA) and reveal a markedly elevated expression of the GLUT1 glucose transporter in lung SqCC, which augments glucose uptake and glycolytic flux...
May 26, 2017: Nature Communications
https://www.readbyqxmd.com/read/28548050/reversible-crystalline-amorphous-phase-transformation-in-si-nanosheets-with-lithi-delithiation
#13
Jeong Min Park, Jae-Hyun Cho, Jung Hoon Ha, Hae-Sik Kim, Sung-Wook Kim, Jaejun Lee, Kyung Yoon Chung, Byung-Won Cho, Heon-Jin Choi
Silicon (Si) has a large theoretical capacity of 4200 mAhg(-1) and has great potential as a high-performance anode material for Li ion batteries (LIBs). Meanwhile, nanostructures can exploit the potential of Si and, accordingly, many zero-dimensional (0D) and one-dimensional (1D) Si nanostructures have been studied. Herein, we report on two-dimensional (2D) Si nanostructures, Si nanosheets (SiNSs), as anodes for LIBs. These 2D Si nanostructures, with a thickness as low 5 nm and widths of several micrometers, show reversible crystalline-amorphous phase transformations with the lithi-/delithiation by the dimensionality of morphology and large surface area...
May 26, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28547882/re-adjusting-the-cut-off-score-of-the-korean-version-of-the-childhood-autism-rating-scale-for-high-functioning-individuals-with-autism-spectrum-disorder
#14
Hyuk-Jin Kwon, Hee-Jeong Yoo, Joo-Hyun Kim, Dong-Hyun Noh, Hyun-Jung Sunwoo, Ye Seul Jeon, Sang-Youn Lee, Ye-Ul Jo, Gui-Young Bong
AIM: The current cut-off score of the Korean version of the Childhood Autism Rating Scale(K-CARS) does not seem sensitive enough to precisely diagnose high-functioning autism. The aim of this study was to identify the optimal cut-off score of K-CARS for diagnosing high-functioning individuals with Autism Spectrum Disorders(ASD). METHODS: A total of 329 participants were assessed by the Korean versions of the Autism Diagnostic Interview - Revised (K-ADI-R), Autism Diagnostic Observation Schedule (K-ADOS), and K-CARS...
May 26, 2017: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28547816/three-component-aminoalkylations-yielding-dihydronaphthoxazine-based-sirtuin-inhibitors-scaffold-modification-and-exploration-of-space-for-polar-side-chains
#15
Steffen Vojacek, Katja Beese, Zayan Alhalabi, Sören Swyter, Anja Bodtke, Carola Schulzke, Manfred Jung, Wolfgang Sippl, Andreas Link
Nonpolar derivatives of heterocyclic aromatic screening hits like the non-selective sirtuin inhibitor splitomicin tend to be poorly soluble in biological fluids. Unlike sp(3) -rich natural products, flat aromatic compounds are prone to stacking and often difficult to optimize into leads with activity in cellular systems. The aim of this work was to identify anchor points for the introduction of sp(3) -rich fragments with polar functional groups into the newly discovered active (IC50  = 5 μM) but nonpolar scaffold 1,2-dihydro-3H-naphth[1,2-e][1,3]oxazine-3-thione by a molecular modeling approach...
May 26, 2017: Archiv der Pharmazie
https://www.readbyqxmd.com/read/28547766/local-release-of-vegf-using-fiber-mats-enables-effective-transplantation-of-layered-cardiomyocyte-sheets
#16
Kenichi Nagase, Yuhei Nagumo, Miri Kim, Hee-Jung Kim, Hei-Won Kyung, Hye-Jin Chung, Hidekazu Sekine, Tatsuya Shimizu, Hideko Kanazawa, Teruo Okano, Seung-Jin Lee, Masayuki Yamato
Cell sheet transplantation is a key tissue engineering technology. A vascular endothelial growth factor (VEGF)-releasing fiber mat is developed for the transplantation of multilayered cardiomyocyte sheets. Poly(vinyl alcohol) fiber mats bearing poly(lactic-co-glycolic acid) nanoparticles that incorporate VEGF are fabricated using electrospinning and electrospray methods. Six-layered cardiomyocyte sheets are transplanted with a VEGF-releasing mat into athymic rats. After two weeks, these sheets produce thicker cardiomyocyte layers compared with controls lacking a VEGF-releasing mat, and incorporate larger-diameter blood vessels containing erythrocytes...
May 26, 2017: Macromolecular Bioscience
https://www.readbyqxmd.com/read/28547764/visibility-of-focal-liver-lesions-comparison-between-kupffer-phase-of-ceus-with-sonazoid-and-hepatobiliary-phase-of-gadoxetic-acid-enhanced-mri
#17
Woo Young Yang, Hee Sun Park, Young Jun Kim, Mi Hye Yu, Sung Il Jung, Hae Jeong Jeon
BACKGROUND: To investigate the agreement between Kupffer phase of Sonazoid contrast-enhanced sonography (CEUS) and hepatobiliary phase of gadoxetic acid-enhanced MRI in the evaluation of focal liver lesions (FLLs). METHODS: One hundred fifty-four FLLs in 154 patients who underwent both Sonazoid CEUS and gadoxetic acid-enhanced liver MRI were included in this retrospective study. FLL visibility on the Kupffer-phase images was graded as one (invisible or isoenhancing), two (vaguely visible or vaguely hypoenhancing), or three (clearly visible or clearly hypoenhancing), and that on the hepatobiliary-phase images of MRI was graded as one (invisible or hyper/isointense), two (vaguely visible or weakly hypointense), or three (clearly visible or strongly hypointense)...
May 26, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28546988/erratum-to-epidemiology-of-burn-injuries-in-nepal-a-systemic-review
#18
Sanjib Tripathee, Surendra Jung Basnet
[This corrects the article DOI: 10.1186/s41038-017-0075-y.].
2017: Burns and trauma
https://www.readbyqxmd.com/read/28546637/proximity-effect-induced-transport-properties-between-mbe-grown-bi1-xsbx-2se3-topological-insulators-and-magnetic-insulator-cofe2o4
#19
Shun-Yu Huang, Cheong-Wei Chong, Yi Tung, Tzu-Chin Chen, Ki-Chi Wu, Min-Kai Lee, Jung-Chun-Andrew Huang, Z Li, H Qiu
In this study, we investigate the proximity effect in topological insulator (TI) and magnetic insulator bilayer system. (Bi1-xSbx)2Se3/CoFe2O4 (CFO) heterostructure was fabricated using molecular beam epitaxy and pulsed laser deposition system respectively. As revealed from the magnetoresistance measurement, the weak anti-localization (WAL) is strongly suppressed by proximity effect in (Bi1-xSbx)2Se3/CFO interface. Modified Hikama-Larkin-Nagaoka equation was used to fit the WAL results so that the size of surface state gap can be extracted successfully...
May 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28546561/dysregulation-of-gut-microbiota-and-chronic-inflammatory-disease-from-epithelial-defense-to-host-immunity
#20
EDITORIAL
Jung Hee Koh, Wan-Uk Kim
No abstract text is available yet for this article.
May 26, 2017: Experimental & Molecular Medicine
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