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Sex evolution

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https://www.readbyqxmd.com/read/29228267/the-effects-of-sex-biased-gene-expression-and-x-linkage-on-rates-of-sequence-evolution-in-drosophila
#1
José Luis Campos, Keira Johnston, Brian Charlesworth
A faster rate of adaptive evolution of X-linked genes compared with autosomal genes (the faster-X effect) can be caused by the fixation of recessive or partially recessive advantageous mutations. This effect should be largest for advantageous mutations that affect only male fitness, and least for mutations that affect only female fitness. We tested these predictions in Drosophila melanogaster by using coding and functionally significant non-coding sequences of genes with different levels of sex-biased expression...
December 8, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/29227268/characteristics-of-west-syndrome-in-georgia-preliminary-results-of-the-prospective-study
#2
A Kvernadze, N Tatishvili, T Kipiani, G Lomidze
West syndrome hasn't been thoroughly investigated in Georgia. The purposes of our study were a) to assess the clinical and etiological peculiarities of West syndrome, based on MRI data and its relation to the long-term outcome; b) to assess the evolution of West syndrome and its relation to patient characteristics; c) to compare the efficacies of treatments with ACTH and antiepileptic drugs (AEDs); d) to evaluate the neuropsychological outcome after 12 and 24 months and their early predictors. We evaluated 31 patients (17 male, 14 female) with infantile spasms...
November 2017: Georgian Medical News
https://www.readbyqxmd.com/read/29225770/sex-determination-mode-does-not-affect-body-or-genital-development-of-the-central-bearded-dragon-pogona-vitticeps
#3
Sarah L Whiteley, Clare E Holleley, Wendy A Ruscoe, Meghan Castelli, Darryl L Whitehead, Juan Lei, Arthur Georges, Vera Weisbecker
Background: The development of male- or female-specific phenotypes in squamates is typically controlled by either temperature-dependent sex determination (TSD) or chromosome-based genetic sex determination (GSD). However, while sex determination is a major switch in individual phenotypic development, it is unknownhow evolutionary transitions between GSD and TSD might impact on the evolution of squamate phenotypes, particularly the fast-evolving and diverse genitalia. Here, we take the unique opportunity of studying the impact of both sex determination mechanisms on the embryological development of the central bearded dragon (Pogona vitticeps)...
2017: EvoDevo
https://www.readbyqxmd.com/read/29222702/molecular-insights-into-the-non-recombining-nature-of-the-spinach-male-determining-region
#4
Tomohiro Kudoh, Mitsuhiko Takahashi, Takayuki Osabe, Atsushi Toyoda, Hideki Hirakawa, Yutaka Suzuki, Nobuko Ohmido, Yasuyuki Onodera
Spinach (Spinacia oleracea L.) is a dioecious plant with male heterogametic sex determination and homomorphic sex chromosomes (XY). The dioecism is utilized for producing commercial hybrid seeds, and hence understanding the molecular-genetic basis of the species' sex determining locus is an important issue for spinach breeding. In this study, seven dominant DNA markers were shown to completely co-segregate with the male-determining gene in segregating spinach populations comprising > 1500 plants. In addition, these seven dominant DNA markers were completely associated with the male-determining gene in over 100 spinach germplasm accessions and cultivars...
December 8, 2017: Molecular Genetics and Genomics: MGG
https://www.readbyqxmd.com/read/29221495/bivariate-longitudinal-data-analysis-a-case-of-hypertensive-patients-at-felege-hiwot-referral-hospital-bahir-dar-ethiopia
#5
Demeke Lakew Workie, Dereje Tesfaye Zike, Haile Mekonnen Fenta
OBJECTIVE: Longitudinal data are often collected to study the evolution of biomedical markers. The study of the joint evolution of response variables concerning hypertension over time was the aim of this paper. A hospital based retrospective data were collected from September 2014 to August 2015 to identify factors that affect hypertensive. The joint mixed effect model with unstructured covariance was fitted. A total of 172 patients screened for antihypertensive drugs treated were longitudinally considered from Felege Hiwot referral...
December 8, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29215911/weird-animals-sex-and-genome-evolution
#6
Jennifer A Marshall Graves
Making my career in Australia exposed me to the tyranny of distance, but it gave me opportunities to study our unique native fauna. Distantly related animal species present genetic variation that we can use to explore the most fundamental biological structures and processes. I have compared chromosomes and genomes of kangaroos and platypus, tiger snakes and emus, devils (Tasmanian) and dragons (lizards). I particularly love the challenges posed by sex chromosomes, which, apart from determining sex, provide stunning examples of epigenetic control and break all the evolutionary rules that we currently understand...
December 7, 2017: Annual Review of Animal Biosciences
https://www.readbyqxmd.com/read/29213179/on-the-role-of-body-size-brain-size-and-eye-size-in-visual-acuity
#7
Alberto Corral-López, Maddi Garate-Olaizola, Severine D Buechel, Niclas Kolm, Alexander Kotrschal
Abstract: The visual system is highly variable across species, and such variability is a key factor influencing animal behavior. Variation in the visual system, for instance, can influence the outcome of learning tasks when visual stimuli are used. We illustrate this issue in guppies (Poecilia reticulata) artificially selected for large and small relative brain size with pronounced behavioral differences in learning experiments and mate choice tests. We performed a study of the visual system by quantifying eye size and optomotor response of large-brained and small-brained guppies...
2017: Behavioral Ecology and Sociobiology
https://www.readbyqxmd.com/read/29209956/cross-sex-genetic-correlation-does-not-extend-to-sexual-size-dimorphism-in-spiders
#8
Eva Turk, Matjaž Kuntner, Simona Kralj-Fišer
Males and females are often subjected to different selection pressures for homologous traits, resulting in sex-specific optima. Because organismal attributes usually share their genetic architectures, sex-specific selection may lead to intralocus sexual conflict. Evolution of sexual dimorphism may resolve this conflict, depending on the degree of cross-sex genetic correlation (r MF) and the strength of sex-specific selection. In theory, high r MF implies that sexes largely share the genetic base for a given trait and are consequently sexually monomorphic, while low r MF indicates a sex-specific genetic base and sexual dimorphism...
December 5, 2017: Die Naturwissenschaften
https://www.readbyqxmd.com/read/29209243/love-influences-reproductive-success-in-humans
#9
Piotr Sorokowski, Agnieszka Sorokowska, Marina Butovskaya, Maciej Karwowski, Agata Groyecka, Bogdan Wojciszke, Bogusław Pawłowski
As love seems to be universal, researchers have attempted to find its biological basis. However, no studies till date have shown its direct association with reproductive success, which is broadly known to be a good measure of fitness. Here, we show links between love, as defined by the Sternberg Triangular Theory of Love, and reproductive success among the Hadza-traditional hunter-gatherer population. We found that commitment and reproductive success were positively and consistently related in both sexes, with number of children showing negative and positive associations with intimacy and passion, respectively, only among women...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29208949/cooperation-and-the-evolution-of-hunter-gatherer-storytelling
#10
Daniel Smith, Philip Schlaepfer, Katie Major, Mark Dyble, Abigail E Page, James Thompson, Nikhil Chaudhary, Gul Deniz Salali, Ruth Mace, Leonora Astete, Marilyn Ngales, Lucio Vinicius, Andrea Bamberg Migliano
Storytelling is a human universal. From gathering around the camp-fire telling tales of ancestors to watching the latest television box-set, humans are inveterate producers and consumers of stories. Despite its ubiquity, little attention has been given to understanding the function and evolution of storytelling. Here we explore the impact of storytelling on hunter-gatherer cooperative behaviour and the individual-level fitness benefits to being a skilled storyteller. Stories told by the Agta, a Filipino hunter-gatherer population, convey messages relevant to coordinating behaviour in a foraging ecology, such as cooperation, sex equality and egalitarianism...
December 5, 2017: Nature Communications
https://www.readbyqxmd.com/read/29207942/a-reconstruction-of-sexual-modes-throughout-animal-evolution
#11
Daniel A Sasson, Joseph F Ryan
BACKGROUND: Although most extant animals have separate sexes, simultaneous hermaphrodites can be found in lineages throughout the animal kingdom. However, the sexual modes of key ancestral nodes including the last common ancestor (LCA) of all animals remain unclear. Without these data, it is difficult to infer the reproductive-state transitions that occurred early in animal evolution, and thus a broad understanding of the evolution of animal reproduction remains elusive. In this study, we use a composite phylogeny from four previously published studies, two alternative topologies (ctenophores or sponges as sister to the rest of animals), and multiple phylogenetic approaches to conduct the most extensive analysis to date of the evolution of animal sexual modes...
December 6, 2017: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/29205083/a-multifactorial-investigation-of-captive-gorillas-intraspecific-gestural-laterality
#12
Jacques Prieur, Simone Pika, Stéphanie Barbu, Catherine Blois-Heulin
Multifactorial investigations of intraspecific laterality of primates' gestural communication aim to shed light on factors that underlie the evolutionary origins of human handedness and language. This study assesses gorillas' intraspecific gestural laterality considering the effect of various factors related to gestural characteristics, interactional context and sociodemographic characteristics of signaller and recipient. Our question was: which factors influence gorillas' gestural laterality? We studied laterality in three captive groups of gorillas (N = 35) focusing on their most frequent gesture types (N = 16)...
December 5, 2017: Laterality
https://www.readbyqxmd.com/read/29202694/alternative-patterns-of-sex-chromosome-differentiation-in-aedes-aegypti-l
#13
Corey L Campbell, Laura B Dickson, Saul Lozano-Fuentes, Punita Juneja, Francis M Jiggins, William C Black
BACKGROUND: Some populations of West African Aedes aegypti, the dengue and zika vector, are reproductively incompatible; our earlier study showed that divergence and rearrangements of genes on chromosome 1, which bears the sex locus (M), may be involved. We also previously described a proposed cryptic subspecies SenAae (PK10, Senegal) that had many more high inter-sex FST genes on chromosome 1 than did Ae.aegypti aegypti (Aaa, Pai Lom, Thailand). The current work more thoroughly explores the significance of those findings...
December 4, 2017: BMC Genomics
https://www.readbyqxmd.com/read/29197933/impact-of-low-dose-steroids-on-hba1c-levels-and-development-of-pre-diabetes-and-nodat-in-non-diabetic-renal-transplant-recipients-on-long-term-follow-up
#14
F P Tillmann, M Schmitz, L C Rump, I Quack
BACKGROUND: This study aimed to evaluate the impact of 5 mg of prednisolone/day on HbA1c levels and its association with the development of pre-diabetes and new-onset diabetes mellitus (NODAT) in non-diabetic first renal transplant recipients on long-term follow-up. METHODS: Four hundred patients were analysed on an average of 4.1 ± 3.0 years after successful transplantation: 96 (24%) were steroid-free and 304 (76%) treated with 5 mg of prednisolone/day combined with cyclosporine A (CsA) or tacrolimus (Tac) as part of their immunosuppressive protocol...
December 2, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/29197555/temperature-vs-estrogen-induced-sex-determination-in-caiman-latirostris-embryos-both-females-but-with-different-expression-patterns-of-key-molecules-involved-in-ovarian-development
#15
Canesini Guillermina, Stoker Cora, H Galoppo Germán, L Durando Milena, V Tschopp María, H Luque Enrique, M Muñoz-de-Toro Mónica, G Ramos Jorge
Caiman latirostris is a species with temperature dependent sex determination (TSD), which implies that the incubation temperature of the eggs is the main factor that determines the sex during a thermo-sensitive period (TSP). However, estrogens play a critical role in this process. The administration of 17β-estradiol (E2) previous to TSP overrides the effects of male incubation temperature, producing phenotypic females. This effect has been defined as sex reversal or estrogen-induced sex determination (E2SD)...
November 29, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/29194059/self-reported-mild-traumatic-brain-injuries-in-relation-to-rumination-and-depressive-symptoms-moderating-role-of-sex-differences-and-a-brain-derived-neurotrophic-factor-gene-polymorphism
#16
Robert L Gabrys, Kaylyn Dixon, Matthew R Holahan, Hymie Anisman
OBJECTIVE: Mild traumatic brain injuries (mTBIs) have frequently been associated with the emergence and persistence of depressive symptoms. However, the factors which contribute to the increased risk for depression after these head injuries remain unclear. Accordingly, we examined the relationship between frequency of self-reported mTBIs and current symptoms of depression and the mediating role of rumination and cognitive flexibility. We also examined whether these relations were moderated by sex differences and the presence of the Val66Met polymorphism in a gene coding for brain-derived neurotrophic factor (BDNF)...
November 21, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29192334/putative-independent-evolutionary-reversals-from-genotypic-to-temperature-dependent-sex-determination-are-associated-with-accelerated-evolution-of-sex-determining-genes-in-turtles
#17
Robert Literman, Alexandria Burrett, Basanta Bista, Nicole Valenzuela
The evolutionary lability of sex-determining mechanisms across the tree of life is well recognized, yet the extent of molecular changes that accompany these repeated transitions remain obscure. Most turtles retain the ancestral temperature-dependent sex determination (TSD) from which multiple transitions to genotypic sex determination (GSD) occurred independently, and two contrasting hypotheses posit the existence or absence of reversals back to TSD. Here we examined the molecular evolution of the coding regions of a set of gene regulators involved in gonadal development in turtles and several other vertebrates...
December 1, 2017: Journal of Molecular Evolution
https://www.readbyqxmd.com/read/29187926/-management-of-moderate-and-severe-dysthyroid-orbitopathy-about-22-cases
#18
Nadia Daldoul, Leila Knani, Faten Gatfaoui, Hechmi Mahjoub
Our study aimed to describe the therapeutic management of moderate and severe dysthyroid orbitopathies and to evaluate the factors associated with optic neuropathy as well as the prognostic factors of poor visual outcome using a statistical analysis. We conducted a retrospective study of 22 patients presenting with moderate to severe dysthyroid orbitopathy in at least one eye and hospitalized in the Department of Ophthalmology at the University Hospital Farhat Hached, Sousse over the period from 1998 to 2015...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/29185614/permanent-pacing-after-transcatheter-aortic-valve-implantation-incidence-predictors-and-evolution-of-left-ventricular-function
#19
Cláudio Monteiro, Andres Di Leoni Ferrari, Paulo Ricardo Avancini Caramori, Luiz Antonio Ferreira Carvalho, Dimytri Alexandre de Alvim Siqueira, Luiz Eduardo Koenig São Thiago, Marco Perin, Valter C de Lima, Enio Guérios, Fabio Sandoli De Brito
BACKGROUND: Transcatheter aortic valve implantation (TAVI) is a well-established procedure; however, atrioventricular block requiring permanent pacemaker implantation (PPI) is a common complication. OBJECTIVES: To determine the incidence, predictors and clinical outcomes of PPI after TAVI, focusing on how PPI affects left ventricular ejection fraction (LVEF) after TAVI. METHODS: The Brazilian Multicenter TAVI Registry included 819 patients submitted to TAVI due to severe aortic stenosis from 22 centers from January/2008 to January/2015...
November 27, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/29183018/cytogenetic-characterization-of-a-population-of-acanthodactylus-lineomaculatus-dum%C3%A3-ril-and-bibron-1839-reptilia-lacertidae-from-southwestern-morocco-and-insights-into-sex-chromosome-evolution
#20
Massimo Giovannotti, Paola Nisi Cerioni, Tahar Slimani, Andrea Splendiani, Alessio Paoletti, Adnane Fawzi, Ettore Olmo, Vincenzo Caputo Barucchi
Acanthodactylus lineomaculatus is now regarded as an ecotype of A. erythrurus with which it has been recently synonymized. Despite the wide range of A. erythrurus, karyological data for this species are scarce and limited to classical cytogenetic studies carried out in individuals from only 2 locations (central Spain and Spanish enclave of Melilla on the northwestern Mediterranean Moroccan coast). Here, for the first time, we cytogenetically characterized individuals of A. lineomaculatus from the southwestern Moroccan Atlantic coast with the aim to increase the karyological knowledge of this wide-ranging species and to assess if any chromosomal changes can be found in this ecotype in comparison to other populations of this species...
November 29, 2017: Cytogenetic and Genome Research
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