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Titia F Beek, Peggy T Cohen-Kettenis, Walter P Bouman, Annelou L C de Vries, Thomas D Steensma, Gemma L Witcomb, Jon Arcelus, Christina Richards, Els Elaut, Baudewijntje P C Kreukels
The World Health Organization (WHO) is currently updating the tenth version of their diagnostic tool, the International Classification of Diseases (ICD, WHO, 1992). Changes have been proposed for the diagnosis of Transsexualism (ICD-10) with regard to terminology, placement and content. The aim of this study was to gather the opinions of transgender individuals (and their relatives/partners) and clinicians in the Netherlands, Flanders (Belgium) and the United Kingdom regarding the proposed changes and the clinical applicability and utility of the ICD-11 criteria of 'Gender Incongruence of Adolescence and Adulthood' (GIAA)...
2016: PloS One
Ines Dourado, Luís Augusto V da Silva, Laio Magno, Maycon Lopes, Caio Cerqueira, Adriana Prates, Sandra Brignol, Sarah MacCarthy
Trans persons, including transvestites and transsexual women, show disproportionately high HIV/AIDS rates when compared to the rest of the population. However, few quantitative/qualitative studies have addressed trans persons in Brazil. Thus, a team of researchers from different fields is developing an interdisciplinary research project with the objective of shedding light on living conditions and ways of life among transvestites and transsexual women, while investigating determinant factors for HIV infection, syphilis, and hepatitis B and C...
October 10, 2016: Cadernos de Saúde Pública
Irene Folaron, Monica Lovasz
Retention standards and policies applied to active duty members in the U.S. military who identify as transgender have recently been in evolution. The Secretary of Defense recently released a new directive allowing transgender members to serve openly with the option to transition gender while in active duty, abrogating the old policy disqualifying transgender members from continued service. There is a reasonable expectation that some may pursue medical and surgical options toward gender transition. The clinical pathway for gender transition relies heavily on Mental Health and Endocrinology services...
October 2016: Military Medicine
Giuseppe Loverro, Leonardo Resta, Miriam Dellino, Di Naro Edoardo, Maria Arcangela Cascarano, Matteo Loverro, Salvatore Andrea Mastrolia
OBJECTIVE: Female-to-male transition remains a specific clinical indication for long-term testosterone administration. There is a limited number of studies dealing with the effect of androgen treatment on their female receptive targets (mainly breast and uterus) and the knowledge in this field is scarce and, sometimes, contradictory. MATERIALS AND METHODS: We performed a prospective study including 12 patients aged between 20 years and 32 years, with a diagnosis of gender dysphoria, treated with parenteral testosterone administration before sexual reassignment surgery...
October 2016: Taiwanese Journal of Obstetrics & Gynecology
Alessandra D Fisher, Giovanni Castellini, Jiska Ristori, Helen Casale, Emanuele Cassioli, Carolina Sensi, Egidia Fanni, Anna Maria Letizia Amato, Eva Bettini, Maddalena Mosconi, Davide Dèttore, Valdo Ricca, Mario Maggi
CONTEXT: To date, there are few studies investigating the impact of body changes induced by cross-sex hormonal treatment (CHT) on psychobiological well-being in gender-dysphoric persons (GDs). OBJECTIVE: The objective of the study was to assess whether CHT-related body changes affect psychobiological well-being in GDs. METHODS: A consecutive series of 359 GDs was considered for a cross-sectional section of the study. In addition, 54 GDs were studied in a 2-year follow-up...
October 4, 2016: Journal of Clinical Endocrinology and Metabolism
Paul Neuville, Nicolas Morel-Journel, Delphine Maucourt-Boulch, Alain Ruffion, Philippe Paparel, Jean-Etienne Terrier
INTRODUCTION: The creation of a neophallus is a complex surgery that must meet functional and esthetic requirements. It is a long and demanding surgical process whose final stage consists of the implantation of a rigid or inflatable material that can be used to reproduce an erection. Data in the literature are scarce, with only the pioneering series present, which includes the use of the first devices and techniques. AIM: To report the outcome of patients with phalloplasty after implantation of erectile implants using standardized surgical techniques and the use of recent prosthesis types with or without a vascular graft...
September 29, 2016: Journal of Sexual Medicine
Tim C van de Grift, Baudewijntje P C Kreukels, Lian Elfering, Müjde Özer, Mark-Bram Bouman, Marlon E Buncamper, Jan Maerten Smit, Margriet G Mullender
INTRODUCTION: Transmen are generally dissatisfied with their breasts and often opt for mastectomy. However, little is known about the specific effects of this procedure on this group's body image. AIM: To prospectively assess the effect of mastectomy on the body image of transmen, including cognitive, emotional, and behavioral aspects. METHODS: During a 10-month period, all transmen applying for mastectomy were invited to participate in this study...
September 22, 2016: Journal of Sexual Medicine
Inas A Mazen
This article reviews the literature on intersexuality (disorders of sex development [DSD]) and transsexuality in Egypt. Egypt's resources for the diagnosis and treatment of rare conditions, such as DSD and transsexualism, are quite limited. The birth of a child with a DSD is likely to be stressful, especially in regard to decisions on gender assignment, and genital abnormalities are associated with stigma and shame. Gender assignment may be biased toward the male gender, because female infertility precludes marriage and female gender adversely affects employment prospects and inheritance...
September 20, 2016: Archives of Sexual Behavior
Shahryar Cohanzad
OBJECTIVE: To introduce a postoperative protocol to optimize the final size of the penis in patients undergoing metoidioplasty. PATIENTS AND METHODS: Fourteen patients with the mean age of 29.3 years (8-40 ± 11.7), ten female transsexuals (46 xx karyotype) and four with 5-alpha-reductase deficiency syndrome (5ARDS) who had undergone extensive metoidioplasty entered a penile improvement protocol (PIP) between 2007 and 2015 at a specialized clinic in a general hospital in Tehran, Iran...
September 19, 2016: Aesthetic Plastic Surgery
M S Irwig, K Childs, A B Hancock
There is sparse prospective data on the effects of testosterone therapy on the voices of transgender men (also referred to as trans men or female-to-male transsexuals). Our aim was to investigate the timing and degree of voice deepening over 12 months among an ethnically diverse sample of transgender men. This was a prospective 12-month study at an academic outpatient endocrinology clinic and speech and voice center. The participants were seven transgender men naïve to testosterone therapy. All patients received two voice assessments at baseline and one assessment at 3, 6, 9, and 12 months while on intramuscular testosterone esters...
September 19, 2016: Andrology
Andrew S Lea
In 1966, the Johns Hopkins University School of Medicine became the first American medical institution to perform sex reassignment surgeries. This article interrogates the relationship between the emergence of this clinical therapy in the United States and the changing medical understandings of the contemporaneous condition it was intended to address - 'transsexualism.' I argue that, during the mid-to-late twentieth century, therapeutic practices and theories about the etiology of transsexualism were mutually constitutive...
September 2016: Endeavour
Shane D Morrison, Afaaf Shakir, Krishna S Vyas, Johanna Kirby, Curtis N Crane, Gordon K Lee
BACKGROUND: Acquired or congenital absence of the penis can lead to severe physical limitations and psychological outcomes. Phallic reconstruction can restore various functional aspects of the penis and reduce psychosocial sequelae. Moreover, some female-to-male transsexuals desire creation of a phallus as part of their gender transition. Because of the complexity of phalloplasty, there is not an ideal technique for every patient. This review sets out to identify and critically appraise the current literature on phalloplasty techniques and outcomes...
September 2016: Plastic and Reconstructive Surgery
Georgia Dacakis, Jennifer M Oates, Jacinta M Douglas
OBJECTIVES: The Transsexual Voice Questionnaire (TVQ(MtF)) is a population-specific self-report tool designed to capture the perceptions of male-to-female transsexual women (MtF women) regarding their vocal functioning and the voice-related impact on their everyday life. The aim of this study was to further the psychometric evaluation of the TVQ(MtF) by examining its construct validity and confirming its reliability. STUDY DESIGN: This is a prospective validity and reliability study...
August 8, 2016: Journal of Voice: Official Journal of the Voice Foundation
Sam Winter, Griet De Cuypere, Jamison Green, Robert Kane, Gail Knudson
ICD-11 (the eleventh edition of the World Health Organization International Statistical Classification of Diseases and Related Health Problems) is due for approval in 2018. For transgender health care, the most important proposals for ICD-11 are as follows: (1) the five ICD-10 diagnoses (most notably Transsexualism and Gender Identity Disorder of Childhood) currently in Chapter 5 (Mental and Behavioural Disorders) will be replaced by two Gender Incongruence diagnoses, one of Adolescence and Adulthood and the other of Childhood (GIC), and (2) these two diagnoses will be located in a new chapter provisionally named Conditions Related to Sexual Health...
October 2016: Archives of Sexual Behavior
Hannes Sigurjonsson, Johan Rinder, Ebba K Lindqvist, Filip Farnebo, T Kalle Lundgren
BACKGROUND: Gender reassignment surgery due to transsexualism (International Classification of Diseases, Tenth Revision: F64.0) is a procedure becoming increasingly common worldwide as a result of a significant increase in diagnostic incidence. Several methods have been described for this complex surgery, but no internationally agreed upon gold standard exists, in particular with regard to which methods allow for creating a sufficient neovaginal depth. METHODS: We use a 2-stage technique using solely penile skin for creating a neovaginal cavity and present the long-term outcome in terms of measured neovaginal depth...
June 2016: Plastic and Reconstructive Surgery. Global Open
Silke Van Damme, Marjan Cosyns, Sofie Deman, Zoë Van den Eede, John Van Borsel
OBJECTIVES: This study aimed to review the evidence of the effectiveness of pitch-raising surgery performed in male-to-female transsexuals. METHODS: A search for studies was performed in PubMed, Web of Science, Science Direct, EBSCOhost, Google Scholar, and the references in retrieved manuscripts, using as keywords "transsexual" or "transgender" combined with terms related to voice surgery. We included eight studies using cricothyroid approximation, six studies using anterior glottal web formation, and six studies using other surgery types or a combination of surgical techniques, leading to 20 studies in total...
July 28, 2016: Journal of Voice: Official Journal of the Voice Foundation
Anna Martha Vaitses Fontanari, Angelo Brandelli Costa, Bianca Aguiar, Cíntia Tusset, Tahiana Andreazza, Maiko Schneider, Eduarda Dias da Rosa, Bianca Machado Borba Soll, Karine Schwarz, Dhiordan Cardoso da Silva, André Oliveira Borba, Andressa Mueller, Raffael Massuda, Maria Inês Rodrigues Lobato
Serum BDNF levels are significantly decreased in transsexual Brazilian women when compared to cis-sexual men. Since transsexual men are also exposed to chronic social stress and have a high prevalence of associated psychopathologies, it is plausible to inquire if BDNF serum levels are altered in transsexual men as well. Therefore, our objective was to evaluate differences in BDNF serum level of transsexual men when compared to cis-sexual men and women. Our sample comprises 27 transsexual men, 31 cis-sexual women and 30 cis-sexual men recruited between 2011 and 2015...
September 6, 2016: Neuroscience Letters
Michele J Eliason, Asa Radix, Jane A McElroy, Samantha Garbers, Suzanne G Haynes
BACKGROUND: Terminology related to sexuality and gender is constantly evolving, and multiple factors are at play when individuals answer questions on surveys. METHODS: We examined patterns of responding to the National Health Interview Survey (NHIS) sexual identity questions in a multisite health intervention study for lesbian and bisexual women aged 40 to 84 years. RESULTS: Of 376 participants, 80% (n = 301) chose "lesbian or gay," 13% (n = 49) selected "bisexual," 7% (n = 25) indicated "something else," and 1 participant chose "don't know the answer...
July 7, 2016: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
Maciej Misołek, Ewa Niebudek-Bogusz, Joanna Morawska, Bogusława Orecka, Wojciech Ścierski, Grażyna Lisowska
The paper presents a case study of a transsexual patient who underwent a voice pitch elevation surgery performed in Poland for the first time. The human voice is a reflection of the working of hormones and human psyche. This fact is of particular importance in transsexualism, a disorder consisting in incongruence between the individual's biological sex and their identified gender. For many transsexual people, especially of the MTF (male to female) type, who have undergone hormonal and surgical sex change, the voice still presents a major problem, causing difficulties in everyday life...
2016: Endokrynologia Polska
Hyung-Tae Kim
OBJECTIVES/HYPOTHESIS: Voice feminization has been developed with various surgical techniques to increase voice pitch. The purpose of this study was to evaluate 12 years of experience using a new endoscopical surgical technique, vocal fold shortening and retrodisplacement of the anterior commissure (VFSRAC) and retraining the voice pattern performed in female patients with androphonia or male-to-female transsexuals. STUDY DESIGN: Retrospective study. METHODS: A retrospective study was performed on 362 patients who underwent VFSRAC (34 with androphonia, eight with androgenital syndrome, four with aplastic anemia treated with androgens, three with pseudohermaphroditism, and 313 male-to-female [MTF] transsexuals) and phonatory pattern rehabilitation between 2003 and 2014...
June 21, 2016: Laryngoscope
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