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JOURNAL ARTICLE
Silvia Alberti-Violetti, Gianluca Avallone, Cristiana Colonna, Gianluca Tavoletti, Luigia Venegoni, Valentina Merlo, Stefano Cambiaghi, Angelo V Marzano, Emilio Berti, Riccardo Cavalli
BACKGROUND: Primary cutaneous lymphomas are neoplasms of the immune system with a distinct tropism for the skin and an absence of extracutaneous manifestations at the time of diagnosis. Studies focusing on cutaneous lymphomas in children and adolescents remain scarce and often do not encompass the rare subtypes. OBJECTIVES: To address this knowledge gap by describing the clinical, histological and molecular characteristics of a large group of paediatric patients affected by primary cutaneous lymphoma...
April 23, 2024: Journal of the European Academy of Dermatology and Venereology: JEADV
#2
JOURNAL ARTICLE
Luca Potestio, Cataldo Patruno, Lucia Genco, Giovanni DI Filippo, Maddalena Napolitano
No abstract text is available yet for this article.
April 2024: Italian journal of dermatology and venereology
#3
JOURNAL ARTICLE
Tse-Yuan Liaw
No abstract text is available yet for this article.
April 2024: Italian journal of dermatology and venereology
#4
JOURNAL ARTICLE
Edoardo Mortato, Silvia Baratta, Riccardo Viola, Anna P DE Caro, Francesco Loconsole
No abstract text is available yet for this article.
April 2024: Italian journal of dermatology and venereology
#5
JOURNAL ARTICLE
Dalma Malvaso, Andrea Chiricozzi, Barbara Fossati, Flaminia Antonelli, Ketty Peris
BACKGROUND: Hidradenitis suppurativa (HS) is a debilitating chronic skin disease; its therapeutic approach often requires combined medical and surgical treatment. METHODS: The aim of this study was to assess the efficacy and safety of the surgical approach combined with different pharmacological treatments, evaluating the proportion of patients achieving the hidradenitis suppurativa clinical response (HiSCR), along with the incidence of postoperative complications, and local recurrence...
April 2024: Italian journal of dermatology and venereology
#6
JOURNAL ARTICLE
Valentina Perrone, Silvia Sabatino, Arianna Avitabile, Melania Dovizio, Melania Leogrande, Luca Degli Esposti
BACKGROUND: This real-world analysis aimed at characterizing patients hospitalized for alopecia areata (AA) in Italy, focusing on comorbidities, treatment patterns and the economic burden for disease management. METHODS: Administrative databases of healthcare entities covering 8.9 million residents were retrospectively browsed to include patients of all ages with hospitalization discharge diagnosis for AA from 2010 to 2020. The population was characterized during the year before the first AA-related hospitalization (index-date) and followed-up for all the available successive period...
April 2024: Italian journal of dermatology and venereology
#7
JOURNAL ARTICLE
Beata Bień, Piotr K Krajewski, Jacek C Szepietowski
BACKGROUND: Acne is a chronic inflammatory disease predominantly affecting young people. This study was undertaken to assess the impact of acne in young adults on their major life-changing decisions (MLCD), paying attention to the relationships between major life-changing decisions profile (MLCDP) and Quality of Life (QoL), feeling of stigmatization and acceptance of the disease. METHODS: The study was performed on 213 young people diagnosed with acne. A variety of questionnaires were employed to measure the clinical and psychological aspects of acne...
April 2024: Italian journal of dermatology and venereology
#8
JOURNAL ARTICLE
Federico Bardazzi, Alessandro Pileri, Giacomo Clarizio, Anastasia Pilipenko, Camilla Loi, Lidia Sacchelli, Diego Abbenante
BACKGROUND: Psoriasis (P) and atopic dermatitis (AD) share some common characteristics. The resulting clinical picture with shared manifestations is a new entity called psoriasis dermatitis (PD), atopic psoriasis or psorema. The purpose of this study was to identify the clinical manifestations of this new dermatological condition, focusing on the adult population. METHODS: We recruited adult patients from two outpatient clinics, the "severe psoriasis" and the "adult atopic dermatitis," between January 1st , 2021, and December 31st , 2021...
April 2024: Italian journal of dermatology and venereology
#9
JOURNAL ARTICLE
Giulia Bazzacco, Iris Zalaudek, Enzo Errichetti
INTRODUCTION: Over the few last decades, dermoscopy has become an invaluable and popular imaging technique that complements the diagnostic armamentarium of dermatologists, being employed for both tumors and inflammatory diseases. Whereas distinction between neoplastic and inflammatory lesions is often straightforward based on clinical data, there are some scenarios that may be troublesome, e.g., solitary inflammatory lesions or tumors superimposed to a widespread inflammatory condition that may share macroscopic morphological findings...
April 2024: Italian journal of dermatology and venereology
#10
JOURNAL ARTICLE
Luana A Nurla, Ana-Maria Forsea
Every year in Europe over 150,000 new cases of melanoma are reported and over 25,000 lives are lost to this tumor. Incidence has been rising rapidly, faster than for any other cancer, and it is expected to continue to do so in most regions. Mortality also crept up, decades-long, with only few very recent exceptions. Thus, melanoma remains a public health problem that will not go away soon, nor easy. Some notable progress has been made in the last decade in the fight against this tumor. Registration and reporting for skin cancers improved across Europe...
April 2024: Italian journal of dermatology and venereology
#11
JOURNAL ARTICLE
Clio Dessinioti, Konstantinos Liopyris, Alexander J Stratigos
The assessment of patients with a lesion raising the suspicion of an invasive cutaneous squamous cell carcinoma (cSCC) is a frequent clinical scenario. The management of patients with cSCC is a multistep approach, starting with the correct diagnosis. The two main diagnostic goals are to differentiate from other possible diagnoses and correctly recognize the lesion as cSCC, and then to determine the tumor spread (perform staging), that is if the patient has a common primary cSCC or a locally advanced cSCC, or a metastatic cSCC (with in-transit, regional lymph nodal, or rarely distant metastasis)...
April 2024: Italian journal of dermatology and venereology
#12
JOURNAL ARTICLE
Luca Stingeni, Leonardo Bianchi, Elena S Caroppo, Anna Belloni Fortina, Francesca Caroppo, Monica Corazza, Alessandro Borghi, Rosella Gallo, Ilaria Trave, Silvia M Ferrucci, Andrea Beretta, Fabrizio Guarneri, Emanuela Martina, Maddalena Napolitano, Mario DE Lucia, Cataldo Patruno, Luigi Bennardo, Paolo Romita, Caterina Foti, Marta Tramontana, Rossella Marietti, Giuseppe Argenziano, Katharina Hansel
Allergic contact dermatitis (ACD) is a common inflammatory skin disease caused by delayed hypersensitivity to chemical and biotic contact allergens. ACD significantly affects the patients' quality of life negatively impacting both occupational and non-occupational settings. Patch testing is the gold standard diagnostic in vivo test to precise the ACD etiology and to correctly perform prevention. According to the Italian Medicines Agency (AIFA) legislative decree no. 178 of 29th May 1991, allergens are defined as medicines and therefore they are subject to strict regulation...
April 2024: Italian journal of dermatology and venereology
#13
J Riera-Monroig, R A Feltes-Ochoa, I Quiles-Melero, A Martin-Gorgojo
Over the past few years, venereal or sexually transmitted infections (STIs) have been on the rise worldwide requiring additional specialized monographic consultations to specifically treat STIs. Therefore, the Spanish Academy of Dermatology and Venereology (AEDV) Research Working Group on STIs and HIV has drafted this document with the necessary requirements in terms of infrastructure, personnel, technology, specific materials for sample collection, and needs for current therapeutic options. Strict emphasis is placed on the protection of patient privacy...
April 20, 2024: Actas Dermo-sifiliográficas
#14
Diogo de Sousa, Pedro Garrido, Daniel Nunes, Carlos Lemos, João Borges-Costa
Human immunodeficiency virus (HIV) transmission remains an important health issue, with a high burden that is felt across the world. This work aims to analyze the demographic, clinical, and laboratory characteristics of newly diagnosed patients with HIV in a Department of Dermatology and Venereology. A retrospective observational study was conducted from all health records of newly diagnosed patients with HIV from a Dermatology unit from January 2011 through December 2020. A total of 134 patients with new HIV diagnoses were included in the analysis...
April 20, 2024: Actas Dermo-sifiliográficas
#15
JOURNAL ARTICLE
N Marsidi, R Ottevanger, Y E Demir, S van Beugen, J J Goeman, R E Genders
BACKGROUND: Knowledge of the psychosocial impact of facial skin surgery on patients can help improve counselling strategies. OBJECTIVES: The objective was to measure the psychological impact of facial skin cancer surgery on patients over a 1-year period. Secondary objective was to measure the difference between Mohs micrographic surgery (MMS) and conventional excision (CE) on these parameters. METHODS: This observational survey study was conducted between March 2019 and July 2020...
April 22, 2024: Journal of the European Academy of Dermatology and Venereology: JEADV
#16
JOURNAL ARTICLE
Hannah Wecker, Stefanie Ziehfreund, Sebastian Sitaru, Emma K Johansson, Jesper Elberling, Anaïs Doll, Electra Nicolaidou, Emanuele Scala, Michael J Boffa, Lea Schmidt, Mariusz Sikora, Tiago Torres, Pavel V Chernyshov, Alexander Zink
BACKGROUND: The complexity, high prevalence, and substantial personal and socioeconomic burden collectively render atopic dermatitis (AD) a major public health concern. Using crowdsourced Internet data has the potential to provide unique insights into this concern, as demonstrated by several previous studies. However, a comprehensive comparison across European countries remains lacking. OBJECTIVES: The study aimed to investigate AD-related web searches across Europe to assess spatiotemporal variations and associations between disease-related and external factors...
April 20, 2024: Journal of the European Academy of Dermatology and Venereology: JEADV
#17
JOURNAL ARTICLE
Hsin-Hui Hsu, Huei-Jing Wang, Yng Sun, Cheng-Che Lan
No abstract text is available yet for this article.
April 18, 2024: Italian journal of dermatology and venereology
#18
JOURNAL ARTICLE
Alessandro Borghi, Fabrizio Guarneri, Lucrezia Pacetti, Irene Donelli, Natale Schettini, Daniela Ravara, Leda Montesi, Monica Corazza
BACKGROUND: The pathophysiology of sensitive skin is largely unknown and no univocal data on the role of the epidermal barrier impairment have been identified. The aim of this study was to assess whether subjects with or without sensitive skin differ for some biophysical skin parameters, which reflect skin barrier integrity or skin hyperactivity. METHODS: This observational, cross-sectional study included adult volunteers not affected with chronic inflammatory skin diseases who attended the Unit of Dermatology and the Center of Cosmetology of the University of Ferrara, Ferrara, Italy, between March 2021 and November 2022...
April 18, 2024: Italian journal of dermatology and venereology
#19
JOURNAL ARTICLE
Lihong Wen, Zhexiang Fan, Weichang Huang, Yong Miao, Jiarui Zhang, Bingcheng Liu, Decong Zhu, Damao Dai, Jiaxian Zhang, Demengjie Le, Yufan Zhang, Qian Qu, Zhiqi Hu, Ruosi Chen
BACKGROUND: Depletion or permanent quiescence of the hair follicle stem cell (HFSC) pool underlies pathogenesis in androgenetic alopecia (AGA). Reactivation of quiescent HFSCs is considered an efficient treatment strategy for hair loss. The retinoic acid (RA) is critical to ensure stem cell homeostasis and function. However, little is known about whether RA regulates HFSC homeostasis. We aimed to investigate the impact of RA on HFSC homeostasis and the underlying mechanisms, in order to provide new potential targets for medical therapies of AGA...
April 17, 2024: Journal of the European Academy of Dermatology and Venereology: JEADV
#20
JOURNAL ARTICLE
Qianwen Li, Zhi Yang, Kaili Chen, Ming Zhao, Hai Long, Yueming Deng, Haoran Hu, Chen Jia, Meiyu Wu, Zhidan Zhao, Huan Zhu, Suqing Zhou, Mingming Zhao, Pengpeng Cao, Shengnan Zhou, Yang Song, Guishao Tang, Juan Liu, Jiao Jiang, Wei Liao, Wenhui Zhou, Bingyi Yang, Feng Xiong, Suhan Zhang, Xiaofei Gao, Yiqun Jiang, Wei Zhang, Bo Zhang, Yan-Ling He, Liwei Ran, Chunlei Zhang, Wenting Wu, Quzong Suolang, Hanhuan Luo, Xiaojing Kang, Caoying Wu, Hongzhong Jin, Lei Chen, Qing Guo, Guangji Gui, Shanshan Li, Henan Si, Shuping Guo, Hong-Ye Liu, Xiguang Liu, Guo-Zhang Ma, Danqi Deng, Limei Yuan, Jianyun Lu, Jinrong Zeng, Xian Jiang, Xiaoyan Lyu, Liuqing Chen, Bin Hu, Juan Tao, Yuhao Liu, Gang Wang, Guannan Zhu, Zhirong Yao, Qianyue Xu, Bin Yang, Yu Wang, Yan Ding, Xianxu Yang, Hu Kai, Haijing Wu, Qianjin Lu
BACKGROUND: Lupus erythematosus (LE) is a spectrum of autoimmune diseases. Due to the complexity of cutaneous LE (CLE), clinical skin image-based artificial intelligence is still experiencing difficulties in distinguishing subtypes of LE. OBJECTIVES: We aim to develop a multimodal deep learning system (MMDLS) for human-AI collaboration in diagnosis of LE subtypes. METHODS: This is a multi-centre study based on 25 institutions across China to assist in diagnosis of LE subtypes, other eight similar skin diseases and healthy subjects...
April 15, 2024: Journal of the European Academy of Dermatology and Venereology: JEADV
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