Alejandra Rojas, John Shen, Fátima Cardozo, Cynthia Bernal, Oliver Caballero, Sara Ping, Autum Key, Ali Haider, Yvalena de Guillén, Patricia Langjahr, Maria Eugenia Acosta, Laura Aria, Laura Mendoza, Malvina Páez, Marta Von-Horoch, Patricia Luraschi, Sandra Cabral, María Cecilia Sánchez, Aurelia Torres, Benjamin A Pinsky, Anne Piantadosi, Jesse J Waggoner
In 2019-2020, dengue virus (DENV) type 4 emerged to cause the largest DENV outbreak in Paraguay's history. This study sought to characterize dengue relative to other acute illness cases and use phylogenetic analysis to understand the outbreak's origin. Individuals with an acute illness (≤7 days) were enrolled and tested for DENV nonstructural protein 1 (NS1) and viral RNA by real-time RT-PCR. Near-complete genome sequences were obtained from 62 DENV-4 positive samples. From January 2019 to March 2020, 799 participants were enrolled: 253 dengue (14 severe dengue, 5...
January 25, 2024: Viruses