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Occupational asthma

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https://www.readbyqxmd.com/read/28093530/what-causes-occupational-asthma-in-cleaners
#1
Vicky C Moore, P Sherwood Burge, Alastair S Robertson, Gareth I Walters
No abstract text is available yet for this article.
January 16, 2017: Thorax
https://www.readbyqxmd.com/read/28093332/chitin-and-chitinase-role-in-pathogenicity-allergenicity-and-health
#2
REVIEW
Seema Patel, Arun Goyal
Chitin, a polysaccharide with particular abundance in fungi, nematodes and arthropods is immunogenic. It acts as a threat to other organisms, to tackle which they have been endowed with chitinase enzyme. Even if this enzyme is not present in all organisms, they possess proteins having chitin-binding domain(s) (ChtBD). Many lethal viruses like Ebola, and HCV (Hepatitis C virus) have these domains to manipulate their carriers and target organisms. In keeping with the basic rule of survival, the self-origin (own body component) chitins and chitinases are protective, but that of non-self origin (from other organisms) are detrimental to health...
January 16, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28091866/review-of-diagnostic-challenges-in-occupational-asthma
#3
REVIEW
Jacques A Pralong, Andre Cartier
PURPOSE OF REVIEW: Occupational asthma (OA) is one of the most frequent occupational diseases and its diagnosis is often difficult. This review summarizes its current diagnostic challenges. RECENT FINDINGS: OA is associated with significant health and socio-economic burden. It is underdiagnosed and physicians need to adopt a stepwise approach to confirm the diagnosis. Although early removal from exposure to the offending agent is associated with a better prognosis, physicians should try to confirm the diagnosis of work-related asthma before taking a worker off work...
January 2017: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/28089118/occupational-lung-diseases-from-old-and-novel-exposures-to-effective-preventive-strategies
#4
REVIEW
Paul Cullinan, Xavier Muñoz, Hille Suojalehto, Raymond Agius, Surinder Jindal, Torben Sigsgaard, Anders Blomberg, Denis Charpin, Isabella Annesi-Maesano, Mridu Gulati, Yangho Kim, Arthur L Frank, Metin Akgün, David Fishwick, Rafael E de la Hoz, Subhabrata Moitra
Occupational exposure is an important, global cause of respiratory disease. Unlike many other non-communicable lung diseases, the proximal causes of many occupational lung diseases are well understood and they should be amenable to control with use of established and effective approaches. Therefore, the risks arising from exposure to silica and asbestos are well known, as are the means of their prevention. Although the incidence of occupational lung disease has decreased in many countries, in parts of the world undergoing rapid economic transition and population growth-often with large informal and unregulated workforces-occupational exposures continue to impose a heavy burden of disease...
January 6, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28065800/occupational-asthma-caused-by-sensitization-to-a-cleaning-product-containing-triclosan
#5
Gareth I Walters, Alastair S Robertson, Vicky C Moore, P Sherwood Burge
No abstract text is available yet for this article.
January 5, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28055274/does-the-medical-diagnosis-of-occupational-asthma-coincide-with-the-legal-diagnosis
#6
Zeynep Çelebi Sözener, Ömür Aydın, Yavuz Selim Demirel, Şadan Soyyiğit, Pamir Çerçi, Reşat Kendirlinan, Sevim Bavbek, Gülfem Elif Çelik, Zeynep Mısırlıgil, Betül Ayşe Sin, Arif Keleşoğlu, Dilşad Mungan
Objective The incidence of occupational asthma(OA) is increasing worldwide. In this study, we first aimed to document the rate of diagnosis of OAamong patients who were referred to our clinic from Social Security Institution and factors that affected diagnosis, and secondly, we aimed to assess the consistency of the medical diagnosis and the legal diagnosis. Methods The study involved 132 consecutive patients who were referred to our clinic for evaluation of OA between 2010 and 2015. Detailed workplace history,the tools used in the diagnosis such as peak expiratory flow(PEF) monitoring and bronchial provocation tests and final medical diagnosis were recorded from case files...
January 5, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28035981/potential-inhibitory-influence-of-mirna-210-on-regulatory-t-cells-during-epicutaneous-chemical-sensitization
#7
Carrie Mae Long, Ewa Lukomska, Nikki B Marshall, Ajay Nayak, Stacey E Anderson
Toluene diisocyanate (TDI) is a potent low molecular weight chemical sensitizer and a leading cause of chemical-induced occupational asthma. The regulatory potential of microRNAs (miRNAs) has been recognized in a variety of disease states, including allergic disease; however, the roles of miRNAs in chemical sensitization are largely unknown. In a previous work, increased expression of multiple miRNAs during TDI sensitization was observed and several putative mRNA targets identified for these miRNAs were directly related to regulatory T-cell (Treg) differentiation and function including Foxp3 and Runx3...
December 27, 2016: Genes
https://www.readbyqxmd.com/read/28003835/a-citizen-science-study-documents-environmental-exposures-and-asthma-prevalence-in-two-communities
#8
Samantha Eiffert, Yomi Noibi, Stephen Vesper, Jonathan Downs, Florence Fulk, Juanita Wallace, Melanie Pearson, Andrea Winquist
A citizen-science study was conducted in two low-income, flood-prone communities in Atlanta, Georgia, in order to document environmental exposures and the prevalence of occupant asthma. Teams consisting of a public-health graduate student and a resident from one of the two communities administered a questionnaire, inspected residences for mold growth, and collected a dust sample for quantifying mold contamination. The dust samples were analyzed for the 36 molds that make up the Environmental Relative Moldiness Index (ERMI)...
2016: Journal of Environmental and Public Health
https://www.readbyqxmd.com/read/28001013/management-and-prevention-of-occupational-asthma
#9
Susan M Tarlo
Occupational asthma is a potential preventable form of asthma. This review of diagnosis, management and prevention focuses mainly on publications from the past three years. Early suspicion of the diagnosis is essential for a timely diagnosis and management and the possibility may first be raised by the patient or may need to be elicited by careful history from the health care provider. Objective diagnostic steps are needed, as have been detailed in consensus statements and guidelines. A combination of tests is often needed for diagnosis and these are most easily obtained while the patient is still employed...
December 20, 2016: Minerva Medica
https://www.readbyqxmd.com/read/27988995/socio-economic-status-and-quality-of-life-in-children-with-chronic-disease-a-systematic-review
#10
REVIEW
Madeleine S Didsbury, Siah Kim, Meredith M Medway, Allison Tong, Steven J McTaggart, Amanda M Walker, Sarah White, Fiona E Mackie, Tonya Kara, Jonathan C Craig, Germaine Wong
Reduced quality of life (QoL) is a known consequence of chronic disease in children, and this association may be more evident in those who are socio-economically disadvantaged. The aims of this systematic review were to assess the association between socio-economic disadvantage and QoL among children with chronic disease, and to identify the specific socio-economic factors that are most influential. MEDLINE, Embase and PsycINFO were searched to March 2015. Observational studies that reported the association between at least one measure of social disadvantage in caregivers and at least one QoL measure in children and young people (age 2-21 years) with a debilitating non-communicable childhood disease (asthma, chronic kidney disease, type 1 diabetes mellitus and epilepsy) were eligible...
December 2016: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/27965314/how-voter-turnout-varies-between-different-chronic-conditions-a-population-based-register-study
#11
Reijo Sund, Hannu Lahtinen, Hanna Wass, Mikko Mattila, Pekka Martikainen
BACKGROUND: While poor self-rated health is known to decrease an individual's propensity to vote, disaggregation of the components of health on turnout has thus far received only little attention. This study deepens on the understanding of such relationships by examining the association between chronic diseases and voting. METHODS: The study uses an individual-level register-based data set that contains an 11% random sample of the entire electorate in the 1999 Finnish parliamentary elections...
December 13, 2016: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/27930478/prospective-impact-of-psychiatric-disorders-on-employment-status-and-health-care-use-in-patients-investigated-for-occupational-asthma
#12
Kim L Lavoie, Helene Favreau, Nicola J Paine, Catherine Lemière, Maryann Joseph, Avril Gagnon-Chauvin, André Cartier, Simon L Bacon
OBJECTIVE: We previously reported high rates (34%) of psychiatric disorders (PSY) in patients evaluated for occupational asthma (OA). We determined the impact of PSY on employment status and health care use 12 to 18 months later. METHODS: One hundred ninety-six patients underwent clinical and psychiatric interviews on the day of their OA evaluation. Patients were re-contacted 12to 18 months later to assess employment status and health care use. RESULTS: Results indicated that patients with a PSY at baseline were less likely to be employed (adjusted odds ratio = 2...
December 2016: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/27924719/quantification-of-obeche-wood-allergen-development-of-a-sensitive-sandwich-elisa-for-occupational-exposure-assessment
#13
S Kespohl, P Campo, E Zahradnik, S Maryska, A Aranda-Guerrero, J Rodriguez, T Brüning, M Raulf
Obeche wood is a prominent cause of allergic occupational asthma. To reduce the risk of immunoglobulin E (IgE)-mediated sensitization it is important to assess airborne obeche wood allergen concentrations at exposed workplaces. Therefore, a highly sensitive obeche wood allergen immunoassay was developed and applicability was proven on airborne passive dust samples in Spanish wood workshops. Obeche wood sandwich enzyme-linked immunosorbent assay (ELISA) polyclonal antibodies (pAbs) were developed. Test specificity was verified by different wood and mold extracts...
2016: Journal of Toxicology and Environmental Health. Part A
https://www.readbyqxmd.com/read/27918221/neutrophilic-inflammation-in-asthma-mechanisms-and-therapeutic-considerations
#14
Hun Soo Chang, Tae-Hyeong Lee, Ji Ae Jun, Ae Rin Baek, Jong-Sook Park, So-My Koo, Yang-Ki Kim, Ho Sung Lee, Choon-Sik Park
Neutrophilic airway inflammation represents a pathologically distinct form of asthma and frequently appears in symptomatic adulthood asthmatics. However, clinical impacts and mechanisms of the neutrophilic inflammation have not been thoroughly evaluated up to date. Areas covered: Currently, distinct clinical manifestations, triggers, and molecular mechanisms of the neutrophilic inflammation (namely Toll-like receptor, Th1, Th17, inflammasome) are under investigation in asthma. Furthermore, possible role of the neutrophilic inflammation is being investigated in respect to the airway remodeling...
January 2017: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/27906909/asthma-among-employed-adults-by-industry-and-occupation-21-states-2013
#15
Katelynn E Dodd, Jacek M Mazurek
Workers in various industries and occupations are at risk for work-related asthma* (1). Data from the 2006-2007 adult Behavioral Risk Factor Surveillance System (BRFSS) Asthma Call-back Survey (ACBS), an in-depth asthma survey conducted with respondents who report an asthma diagnosis, from 33 states indicated that up to 48% of adult current asthma might be related to work and could therefore potentially be prevented (2). Identification of the industries and occupations with increased prevalence of asthma might inform work-related asthma intervention and prevention efforts...
December 2, 2016: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/27901009/occupational-asthma-caused-by-inhalable-royal-jelly-and-its-cross-reactivity-with-honeybee-venom
#16
Li-Sha Li, Kai Guan
No abstract text is available yet for this article.
2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27883240/diagnosing-occupational-asthma
#17
REVIEW
O Vandenplas, H Suojalehto, P Cullinan
Making an accurate diagnosis of occupational asthma (OA) is, generally, important. The condition has not only significant health consequences for affected workers, but also substantial socio-economic impacts for workers, their employers and wider society. Missing a diagnosis of OA may lead to continued exposure to a causative agent and progressive worsening of disease; conversely, diagnosing OA when it is not present may lead to inappropriate removal from exposure and unnecessary financial and social consequences...
January 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27875341/occupational-asthma-diagnostic-challenges-and-management-dilemmas
#18
Vrinda Trivedi, Dinesh R Apala, Vivek N Iyer
PURPOSE OF REVIEW: Work-related asthma encompasses both sensitizer-induced and irritant-induced occupational asthma as well as work-exacerbated asthma. This review summarizes current diagnostic and management strategies for occupational asthma. RECENT FINDINGS: Occupational asthma is the most common occupational lung disease in the industrialized world. Over 400 agents have been described to cause occupational asthma. Specific inhalation challenge is often considered the reference method for diagnosis of occupational asthma but specific inhalation challenge as well as other diagnostic tests all generate false positive or false negative results...
November 21, 2016: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/27866540/-the-study-of-the-eosinophil-cd34-progenitor-cells-differentiation-mechanism-of-model-rats-with-occupational-asthma-and-the-intervention-of-warm-and-tonifying-kidney-yang-decoction
#19
Z Y Hu, Y M Jia, S J Wang, J Y Han, T Yu
Objective: To investigate the mechanism of CD34(+) progenitor cell differentiation in rat by observing the change relations between the eosinophils (EOS) and the content of Eotaxin and IL-5 in blood and the CD34(+)/CCR3(+), CD34(+)/IL-5Rα+ in bone marrow after occupational asthma (OA) model rats are simulated, and to observe the effect of WTKYD Trraitional Chinese Medicine intervention. Methods: A total of 40 healthy male SD model rats (200~250 g weight) were randomly divided into model contrast Group, prednisone acetate intervention Group, WTKYD+1/2 prednisone acetate intervention Group and WTKYD intervention Group, 10 in each group, and set a Group for blank contrast...
September 20, 2016: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/27862135/determinants-of-disinfectant-use-among-nurses-in-u-s-healthcare-facilities
#20
Orianne Dumas, Aleta S Wiley, Paul K Henneberger, Frank E Speizer, Jan-Paul Zock, Raphaëlle Varraso, Nicole Le Moual, Krislyn M Boggs, Carlos A Camargo
BACKGROUND: Disinfectant use among healthcare workers has been associated with respiratory disorders, especially asthma. We aimed to describe disinfectants used by U.S. nurses, and to investigate qualitative and quantitative differences according to workplace characteristics and region. METHODS: Disinfectant use was assessed by questionnaire in 8,851 nurses. Hospital characteristics were obtained from the American Hospital Association database. RESULTS: Working in a hospital was associated with higher disinfectant use (OR: 2...
January 2017: American Journal of Industrial Medicine
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