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Occupational asthma

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https://www.readbyqxmd.com/read/28431005/occupational-asthma-caused-by-acrylic-compounds-from-shield-surveillance-1989-2014
#1
G I Walters, A S Robertson, V C Moore, P S Burge
Background: Acrylic monomers (acrylates), methacrylates and cyanoacrylates all cause asthma by respiratory sensitization. Occupational inhalation exposures occur across a variety of industries including health care and dental work, beauty, laboratory science, assembly and plastic moulding. Aims: To examine notifications of occupational asthma caused by acrylic compounds from a UK-based regional surveillance scheme, in order to highlight prevalent exposures and trends in presentation...
April 20, 2017: Occupational Medicine
https://www.readbyqxmd.com/read/28425826/lung-function-and-prevalence-of-respiratory-symptoms-in-norwegian-crab-processing-workers
#2
Marte R Thomassen, Lisbeth Aasmoe, Berit E Bang, Tonje Braaten
BACKGROUND: Seafood processing workers have an increased risk of developing occupational asthma. This has not been studied among Norwegian crab processing workers, nor has the respiratory health of exposed workers been compared to a control group. OBJECTIVES: Assessing the impact of working in the crab processing industry on workers' respiratory health. DESIGN: A cross-sectional study of the respiratory health in two types of crab processing workers compared to a control group...
2017: International Journal of Circumpolar Health
https://www.readbyqxmd.com/read/28400946/the-state-of-asthma-epidemiology-an-overview-of-systematic-reviews-and-their-quality
#3
Jon Genuneit, Annina M Seibold, Christian J Apfelbacher, George N Konstantinou, Jennifer J Koplin, Stefania La Grutta, Kirsty Logan, Carsten Flohr, Michael R Perkin
BACKGROUND: Recently, we have published an overview of systematic reviews in allergy epidemiology and identified asthma as the most commonly reviewed allergic disease. Building on this work, we aimed to investigate the quality of systematic reviews in asthma using the AMSTAR checklist and to provide a reference for future, more in-depth assessment of the extent of previous knowledge. METHODS: We included all 307 systematic reviews indexed with asthma, including occupational asthma, and/or wheeze from our previous search in PubMed and EMBASE up to December 2014 for systematic reviews on epidemiological research on allergic diseases...
2017: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/28383629/ip-10-in-occupational-asthma-review-of-the-literature-and-case-control-study
#4
F Ragusa, P Fallahi
OBJECTIVES: T-helper (Th)2 cytokines are thought to mediate most of the allergic inflammatory responses associated with atopic asthma. But the Th1-related chemokine, interferon (IFN)-γ-induced protein 10 (IP-10)/chemokine (C-X-C motif) ligand (CXCL)10, was the predominant chemokine measured during human allergic pulmonary late-phase reaction. Viral infection and allergens can exacerbate asthma by inducing the accumulation of these chemokines and inflammatory cells in the airway. Short-acting β2-adrenoreceptor agonists, budesonide and formoterol (all important relievers in asthma exacerbation), such as vitamin D3, vitamin C, have been shown to inhibit airway cells inflammatory responses by modulating these chemokines...
March 2017: La Clinica Terapeutica
https://www.readbyqxmd.com/read/28378893/characterization-of-a-novel-allergenic-protein-from-the-octocoral-scleronephthya-gracillima-kuekenthal-that-corresponds-to-a-new-gfp-like-family-named-akane
#5
Yuko Kato, Mitsuru Jimbo, Youichi Sakakibara, Reiko Onizuka, Tatsuya Takahashi, Sachiko Matsuhashi, Hajime Mita, Kei Amada, Yukimitsu Imahara, Kimiko Tanabe, Akihisa Toda, Hisao Kamiya
Certain marine organisms have been known to cause allergic reactions among occupational fishermen. We have previously reported that bronchial asthma among the workers engaged in spiny lobster fishing in Japan was caused by octocorals such as Dendronephthya sp. and Scleronephthya gracillima (previously named Alcyonium gracillimum). Now we have found another octocoral, Scleronephthya gracillima (Kuekenthal), which causes the allergic disease in fishermen. The octocoral was characterized as a new green fluorescent protein (GFP)-like family...
April 5, 2017: Luminescence: the Journal of Biological and Chemical Luminescence
https://www.readbyqxmd.com/read/28360458/prevalence-and-etiological-profile-of-chronic-obstructive-pulmonary-disease-in-nonsmokers
#6
Tariq Mahmood, Ravindra Kumar Singh, Surya Kant, Amitabh Das Shukla, Alok Chandra, Rajneesh Kumar Srivastava
BACKGROUND: Tobacco smoking has been recognized as the most important risk factor for chronic obstructive pulmonary disease (COPD) for a long time, but recent studies have shown that nonsmokers also contribute to a significant proportion of COPD. This study was performed to find out the proportion of nonsmoker individuals among COPD patients and to determine various etiologies in nonsmoker COPD patients. MATERIALS AND METHODS: This study was an observational cross-sectional study conducted in Department of Pulmonary Medicine, MLN Medical College, Allahabad...
March 2017: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/28359263/parental-exposures-to-occupational-asthmagens-and-risk-of-autism-spectrum-disorder-in-a-danish-population-based-case-control-study
#7
Alison B Singer, Igor Burstyn, Malene Thygesen, Preben Bo Mortensen, M Daniele Fallin, Diana E Schendel
BACKGROUND: Environmental exposures and immune conditions during pregnancy could influence development of autism spectrum disorder (ASD) in offspring. However, few studies have examined immune-triggering exposures in relation to ASD. We evaluated the association between parental workplace exposures to risk factors for asthma ("asthmagens") and ASD. METHODS: We conducted a population-based case-control study in the Danish population using register linkage. Our study population consisted of 11,869 ASD cases and 48,046 controls born from 1993 through 2007...
March 31, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28353494/increased-risk-of-tics-in-children-infected-with-enterovirus-a-nationwide-population-based-study
#8
Jiun-Nong Lin, Cheng-Li Lin, Hung-Rong Yen, Chi-Hui Yang, Chung-Hsu Lai, Hsi-Hsun Lin, Chia-Hung Kao
OBJECTIVE: Both tics and enterovirus (EV) infections are common in children. The association between EV infections and tics has been seldom evaluated. The aim of this study was to evaluate the risk of diagnosed tics after EV infections in children. METHODS: A nationwide retrospective cohort study was conducted to determine the risk of tics after EV infections by analyzing data from the National Health Insurance Research Database in Taiwan. Children aged < 18 years with EV infection during 2000 to 2007 were enrolled...
March 27, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28337093/assessment-of-socioeconomic-status-and-control-of-asthma-in-adults
#9
I A Azeez, M M A Ladipo, O M Ige
BACKGROUND: Asthma is a chronic disease which places considerable economic, social and public health burdens on the society. Education, occupation and income are the most widely used indicators of socioeconomic status (SES). Studies have shown increased asthma hospital admissions for those who are materially deprived and increased asthma severity in low social class groups. The aim of this study is to determine the impact of socioeconomic status on control of asthma in adults. METHOD: The study was a cross-sectional analytical one, conducted over a year at the Medical Outpatient Clinic of the University College Hospital Ibadan...
December 2016: Annals of Ibadan Postgraduate Medicine
https://www.readbyqxmd.com/read/28336744/association-of-respiratory-symptoms-and-asthma-with-occupational-exposures-findings-from-a-population-based-cross-sectional-survey-in-telemark-norway
#10
R Abrahamsen, A K M Fell, M V Svendsen, E Andersson, K Torén, P K Henneberger, J Kongerud
OBJECTIVES: The aim of this study was to estimate the prevalence of respiratory symptoms and physician-diagnosed asthma and assess the impact of current occupational exposure. DESIGN: Cross-sectional analyses of the prevalence of self-reported respiratory health and association with current occupational exposure in a random sample of the general population in Telemark County, Norway. SETTINGS: In 2013, a self-administered questionnaire was mailed to a random sample of the general population, aged 16-50, in Telemark, Norway...
March 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/28332418/asthma-status-is-an-independent-risk-factor-for-herpes-zoster-in-children-a-population-based-cohort-study
#11
Su-Jing Chen, Kuang-Hua Huang, Wen-Chen Tsai, Cheng-Li Lin, Yih-Dih Cheng, Chang-Ching Wei
The literature regarding the effects of childhood asthma on the risk of herpes zoster (HZ) is very limited. The aim of this study is to investigate the risks of children developing HZ with asthma. From the National Health Insurance Research Database, a total of 600,891 children were enrolled in this study between 2000 and 2007. The children were matched by age, gender, level of urbanization, and parental occupation. All subjects were followed until the end of 2008. A Cox model was used to estimate the association of asthma on the risk of HZ...
March 23, 2017: Annals of Medicine
https://www.readbyqxmd.com/read/28331347/environmental-triggers-and-avoidance-in-the-management-of-asthma
#12
REVIEW
Clarisse Gautier, Denis Charpin
Identifying asthma triggers forms the basis of environmental secondary prevention. These triggers may be allergenic or nonallergenic. Allergenic triggers include indoor allergens, such as house dust mites (HDMs), molds, pets, cockroaches, and rodents, and outdoor allergens, such as pollens and molds. Clinical observations provide support for the role of HDM exposure as a trigger, although avoidance studies provide conflicting results. Molds and their metabolic products are now considered to be triggers of asthma attacks...
2017: Journal of Asthma and Allergy
https://www.readbyqxmd.com/read/28317175/occupational-respiratory-allergy-in-peach-crop-workers
#13
Remedios Pérez-Calderón, M Ángeles Gonzalo-Garijo, Francisco José Rodríguez-Velasco, Silvia Sánchez-Vega, Borja Bartolomé-Zavala
BACKGROUND: Occupational respiratory diseases in workers of peach tree crops have been reported punctually and have been associated with sensitization to proteins present in both pollen and leaf tree. We report the study of 37 workers with respiratory symptoms related to occupational exposure to peach trees. METHODS: Prick tests and specific IgE determinations were performed with extracts from leaves and branches of peach tree. Immunodetection in leaf extract was realized by SDS-PAGE-immunoblotting with patient sera and rabbit serum anti-Pru p 3...
March 20, 2017: Allergy
https://www.readbyqxmd.com/read/28314756/predicting-occupational-asthma-and-rhinitis-in-bakery-workers-referred-for-clinical-evaluation
#14
Badri Sadat Jonaid, Jos Rooyackers, Erik Stigter, Lützen Portengen, Esmeralda Krop, Dick Heederik
BACKGROUND: Occupational allergic diseases are a major problem in some workplaces like in the baking industry. Diagnostic rules have been used in surveillance but not yet in the occupational respiratory clinic. OBJECTIVE: To develop diagnostic models predicting baker's asthma and rhinitis among bakery workers at high risk of sensitisation to bakery allergens referred to a specialised clinic. METHODS: As part of a medical surveillance programme, clinical evaluation was performed on 436 referred Dutch bakery workers at high risk for sensitisation to bakery allergens...
March 17, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28299723/mold-and-human-health-a-reality-check
#15
REVIEW
Andrea T Borchers, Christopher Chang, M Eric Gershwin
There are possibly millions of mold species on earth. The vast majority of these mold spores live in harmony with humans, rarely causing disease. The rare species that does cause disease does so by triggering allergies or asthma, or may be involved in hypersensitivity diseases such as allergic bronchopulmonary aspergillosis or allergic fungal sinusitis. Other hypersensitivity diseases include those related to occupational or domiciliary exposures to certain mold species, as in the case of Pigeon Breeder's disease, Farmer's lung, or humidifier fever...
March 16, 2017: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/28286155/diagnostic-accuracy-of-inflammatory-markers-for-diagnosing-occupational-asthma
#16
Geneviève Racine, Roberto Castano, André Cartier, Catherine Lemiere
BACKGROUND: The assessment of airway responsiveness and inflammation is key to the investigation of occupational asthma (OA). OBJECTIVE: We sought to assess and compare the diagnostic accuracies of the blood and sputum eosinophil counts and the methacholine challenge for the diagnosis of OA. METHODS: We conducted a retrospective study assessing 618 patients who underwent specific inhalation challenges (SICs) for symptoms suggestive of OA between 2000 and 2015...
March 9, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28276782/respiratory-symptoms-and-lung-function-in-relation-to-wood-dust-and-monoterpene-exposure-in-the-wood-pellet-industry
#17
Håkan Löfstedt, Katja Hagström, Ing-Liss Bryngelsson, Mats Holmström, Anna Rask-Andersen
INTRODUCTION: Wood pellets are used as a source of renewable energy for heating purposes. Common exposures are wood dust and monoterpenes, which are known to be hazardous for the airways. The purpose of this study was to study the effect of occupational exposure on respiratory health in wood pellet workers. MATERIALS AND METHODS: Thirty-nine men working with wood pellet production at six plants were investigated with a questionnaire, medical examination, allergy screening, spirometry, and nasal peak expiratory flow (nasal PEF)...
March 1, 2017: Upsala Journal of Medical Sciences
https://www.readbyqxmd.com/read/28274809/behaviour-of-chemical-respiratory-allergens-in-novel-predictive-methods-for-skin-sensitisation
#18
David Basketter, Alan Poole, Ian Kimber
Asthma resulting from sensitisation of the respiratory tract to chemicals is an important occupational health issue, presenting many toxicological challenges. Most importantly there are no recognised predictive methods for respiratory allergens. Nevertheless, it has been found that all known chemical respiratory allergens elicit positive responses in assays for skin sensitising chemicals. Thus, chemicals failing to induce a positive response in skin sensitisation assays such as the local lymph node assay (LLNA) lack not only skin sensitising activity, but also the potential to cause respiratory sensitisation...
March 6, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/28270447/specific-inhalation-challenge-the-relationship-between-response-clinical-variables-and-lung-function
#19
Chunshao Hu, Maria-Jesus Cruz, Iñigo Ojanguren, Miquel de Homdedeu, Francisco-Javier Gonzalez-Barcala, Xavier Munoz
INTRODUCTION: The specific inhalation challenge (SIC) is considered the gold standard for the diagnosis of occupational asthma (OA). However, its use is not standardised, and the intensity of exposure is regulated empirically. The aim of this study was to identify clinical variables and/or pulmonary function variables able to predict the scale of patients' response to SIC. MATERIAL AND METHODS: All patients who underwent SIC at our centre between 2005 and 2013 were studied...
March 7, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28268255/association-of-migraine-with-asthma-risk-a-retrospective-population-based-cohort-study
#20
Yi-Hao Peng, Kuan-Fei Chen, Wei-Chih Liao, Te-Chun Hsia, Hsuan-Ju Chen, Ming-Chien Yin, Wen-Chao Ho
BACKGROUND: Both migraine and asthma are common health problems in the general population. However, the association between these two disorders is yet to be fully explored. OBJECTIVE: We examined whether adult patients with migraine are at a higher risk of asthma development. METHODS: We used data retrieved from the National Health Insurance Research Database in Taiwan to conduct this nationwide population-based cohort study. We identified 6647 patients aged 20-60 years who were newly diagnosed with migraine between 2000 and 2005 for the migraine group and identified 26 588 patients without migraine for the nonmigraine group...
March 7, 2017: Clinical Respiratory Journal
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