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https://www.readbyqxmd.com/read/29032067/a-rare-case-of-gestational-choriocarcinoma-presenting-as-cornual-ectopic-pregnancy
#1
Vanessa Han, Stephen Kaye
BACKGROUND: Choriocarcinoma associated with cornual pregnancy is extremely rare. To our knowledge, only three other cases have been reported in the literature. CASE: A 38-year-old woman was found to have a left cornual ectopic pregnancy on ultrasound after presenting with abdominal pain, irregular vaginal bleeding, and a positive pregnancy test. Laparoscopy confirmed the diagnosis and she underwent total abdominal hysterectomy. Three weeks later, she presented with vaginal bleeding...
October 11, 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29031177/giant-gastric-lipoma-presenting-as-gi-bleed-enucleation-or-resection
#2
Salah Termos, Ossama Reslan, Omar Alqabandi, Abdullah AlDuwaisan, Saud Al-Subaie, Khalifa Alyatama, Mohammad Alali, Ahmad AlSaleh
INTRODUCTION: Gastric lipomas are unusual benign lesions and account for less than 1% of all tumours of the stomach and 5% of all gastrointestinal lipomas (Thompson et al.2003; Fernandez et al. 1983 [1,2]). Although predominantly asymptomatic and indolent; they may present with gastric outlet obstruction and upper gastrointestinal (GI) bleeding owing to size and ulceration. Only a few cases have been reported, presenting large in size with massive GI bleeding (Alcalde Escribano et al...
October 6, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29024839/hepatic-artery-aneurysm-causing-gastrointestinal-haemorrhage-case-report-and-literature-review
#3
Saulius Palubinskas, Simon Ladefoged Rasmussen
INTRODUCTION: True hepatic artery aneurysms (HAAs) are rare, and when complicated by gastrointestinal haemorrhage, it becomes an even rarer disease entity. The mortality is high and imaging may fail to provide the diagnosis. We present a case of a true hepatic artery aneurysm complicated by a fistula to the duodenum which was first recognised during surgery. PRESENTATION OF CASE: A 77-year-old man presented with upper gastrointestinal haemorrhage. Upper endoscopy revealed an ulceration in the duodenal bulb, which was refractory to endoscopic treatment...
October 4, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29021249/prescribing-ppis
#4
(no author information available yet)
Proton pump inhibitors (PPIs) are widely prescribed and many people remain on them for years. In some, there may be good justification for long-term use; for example, in those with oesophageal stricture, Barrett's oesophagus or a history of a bleeding gastrointestinal ulcer, or to provide gastroprotection in those at high risk of gastrointestinal complications from taking NSAIDs. However, PPIs are often not used in line with clinical guidelines.(1,2) In addition, there are concerns that many people take them for long periods to manage less serious conditions (e...
October 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28992159/compliance-with-accreditation-and-recommended-hospital-care-a-danish-nationwide-population-based-study
#5
Anne Mette Falstie-Jensen, Søren Bie Bogh, Erik Hollnagel, Søren Paaske Johnsen
Objective: To examine the association between compliance with accreditation and recommended hospital care. Design: A Danish nationwide population-based follow-up study based on data from six national, clinical quality registries between November 2009 and December 2012. Setting: Public, non-psychiatric Danish hospitals. Participants: Patients with acute stroke, chronic obstructive pulmonary disease, diabetes, heart failure, hip fracture and bleeding/perforated ulcers...
October 1, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28991993/use-of-the-spectrophotometric-color-method-for-the-determination-of-the-age-of-skin-lesions-on-the-pig-carcass-and-its-relationship-with-gene-expression-and-histological-and-histochemical-parameters
#6
M Vitali, S Conte, M Lessard, K Deschêne, M O Benoit-Biancamano, C Celeste, G Martelli, L Sardi, F Guay, L Faucitano
The presence of lesions on the pig carcass is an indicator of poor animal welfare and has economic impact as it downgrades the carcass value. The assessment of the age of lesions on the carcass may help identify risk factors and ultimately prevent their occurrence. The aim of this study was to assess the age of lesions on pig carcasses through spectrophotometric color evaluation and to relate the results with gene expression and histological and histochemical parameters. A total of 96 barrows were mixed 4 times over 3 d before slaughter and 80 lesions were selected after skin lesion observations to define 4 age categories: < 7 h (T1), 7-25 h (T2), 25-30 h (T3), and 49-54 h (T4)...
September 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28990239/tacrolimus-therapy-for-dermal-arteritis-of-the-nasal-philtrum-refractory-to-surgery-and-anti-inflammatory-therapy-doxycycline-niacinamide-and-topical-fluocinolone-in-a-dog
#7
Frane Banovic, Carmen Jerry, Elizabeth Howerth
BACKGROUND: Dermal arteritis of the nasal philtrum is a rarely reported condition commonly affecting large breed dogs. OBJECTIVE: To describe the effective treatment of nasal philtrum arteritis with topical tacrolimus in one dog. ANIMAL: A 9-year-old, intact male German shorthair pointer dog was presented with well-demarcated deep erythematous ulcers targeting exclusively the skin of the nasal philtrum, accompanied by frequent series of haemorrhage...
October 8, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28990095/kangfuxin-promotes-apoptosis-of-gastric-cancer-cells-through-activating-er%C3%A2-stress-and-autophagy
#8
Pian-Pian Chen, Xiu-Ying Ma, Qian Lin, He-Lin Xu, Hong-Xue Shi, Hong-Yu Zhang, Jian Xiao, Fu-Neng Geng, Ying-Zheng Zhao
Gastric cancer is a leading cause of cancer‑associated mortality worldwide. In studies on the mechanisms of antigastric cancer drugs, autophagy and endoplasmic reticulum (ER) stress have been demonstrated to serve an active role in gastric cancer. The organic extract of Periplaneta americana (also termed American Cockroach), which is named Kangfuxin (KFX) in China, has been used clinically as a traditional Chinese medicine against disorders, including stomach bleeding, gastric ulcers, tuberculosis, burns and trauma...
October 4, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28988197/vonoprazan-prevents-ulcer-recurrence-during-long-term-nsaid-therapy-randomised-lansoprazole-controlled-non-inferiority-and-single-blind-extension-study
#9
Yuji Mizokami, Kazunori Oda, Nobuo Funao, Akira Nishimura, Satoshi Soen, Takashi Kawai, Kiyoshi Ashida, Kentaro Sugano
OBJECTIVE: To assess the non-inferiority of vonoprazan to lansoprazole for secondary prevention of non-steroidal anti-inflammatory drug (NSAID)-induced peptic ulcer (PU) and the safety of vonoprazan during extended use. DESIGN: A phase 3, 24-week, multicenter, randomised, double-blind (DB), active-controlled study, followed by a phase 3, ≥28 week, multicenter, single-blind, parallel-group extension study (EXT) in outpatients (n=642) receiving long-term NSAID therapy who are at risk of PU recurrence...
October 7, 2017: Gut
https://www.readbyqxmd.com/read/28984029/cervicopectoral-flap-as-an-adequate-decision-for-advanced-ameloblastic-carcinoma
#10
I Lozev, I Pidakev, J C Cardoso, U Wollina, G Tchernev
Management of advanced head and neck cancers are often complicated by challenging anatomy, complex reconstructions and long surgical procedures (1). The leading clinical manifestations of patients with ameloblastic carcinomas are large, often painless and rapidly growing mass, swelling, paresthesis, mucosal ulceration, bleeding and tooth mobility (2,3). The tumor may arise from preexistent cysts or develop de novo (2). This article is protected by copyright. All rights reserved.
October 6, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28983850/topical-administration-of-ibuprofen-for-injured-athletes-considerations-formulations-and-comparison-to-oral-delivery
#11
REVIEW
Martin Anthony Christopher Manoukian, Christopher William Migdal, Amode Ravindra Tembhekar, Jerad Alexander Harris, Charles DeMesa
Non-steroidal anti-inflammatory drugs (NSAIDs) are a class of drugs commonly used to treat both the acute and chronic injuries sustained by athletes during training and competition. In many parts of the world, NSAIDs can be purchased over-the-counter and used without any physician oversight. However, the chronic nature of overuse injuries requires NSAIDs to be taken orally for an extended period of time. As a result, they can have significant adverse effects on athletes, namely gastrointestinal (GI), renal, and cardiovascular damage...
October 5, 2017: Sports Medicine—Open
https://www.readbyqxmd.com/read/28983161/etiological-and-endoscopic-profile-of-middle-aged-and-elderly-patients-with-upper-gastrointestinal-bleeding-in-a-tertiary-care-hospital-in-north-india-a-retrospective-analysis
#12
Pranav Mahajan, Vijant Singh Chandail
BACKGROUND: Upper gastrointestinal (GI) bleeding is a common medical emergency associated with significant morbidity and mortality. The clinical presentation depends on the amount and location of hemorrhage and the endoscopic profile varies according to different etiology. At present, there are limited epidemiological data on upper GI bleed and associated mortality from India, especially in the middle and elderly age group, which has a higher incidence and mortality from this disease...
July 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28979009/scrub-typhus-an-emerging-threat
#13
Sayantani Chakraborty, Nilendu Sarma
Scrub typhus is caused by Orientia tsutsugamushi (formerly Rickettsia) and is transmitted to humans by an arthropod vector of the Trombiculidae family (Leptotrombidium deliense and L. akamushi). It is the most common re-emerging Rickettsial infection in India and many other South East Asian countries. In fact, scrub typhus is confined geographically to the Asia Pacific region, a billion people are at risk and nearly a million cases are reported every year. Scrub typhus appears particularly to be distributed in the tsutsugamushi triangle which is distributed over a very wide area of 13 million km(2) bound by Japan in the east, through China, the Philippines, tropical Australia in the south, and west through India, Pakistan, possibly to Tibet to Afghanistan, and southern parts of the USSR in the north...
September 2017: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/28960035/lactate-parameters-predict-clinical-outcomes-in-patients-with-nonvariceal-upper-gastrointestinal-bleeding
#14
Seung Hoon Lee, Yang Won Min, Joohwan Bae, Hyuk Lee, Byung Hoon Min, Jun Haeng Lee, Poong Lyul Rhee, Jae J Kim
The predictive role of lactate in patients with nonvariceal upper gastrointestinal bleeding (NVUGIB) has been suggested. This study evaluated several lactate parameters in terms of predicting outcomes of bleeding patients and sought to establish a new scoring model by combining lactate parameters and the AIMS65 score. A total of 114 patients with NVUGIB who underwent serum lactate level testing at least twice and endoscopic hemostasis within 24 hours after admission were retrospectively analyzed. The associations between five lactate parameters and clinical outcomes were evaluated and the predictive power of lactate parameter combined AIMS65s (L-AIMS65s) and AIMS56 scoring was compared...
November 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28951427/an-unexpected-complication-following-uterine-artery-embolisation
#15
Sarah Peters, Michelle Wise, Brendan Buckley
A 35-year-old nulliparous woman underwent uterine artery embolisation (UAE) for heavy menstrual bleeding and anaemia due to fibroids, refractive to medical and surgical treatment.Bilateral UAE was performed after cephazolin prophylaxis and analgesia. Postoperatively, pain and abdominal bloating were prominent. Symptoms were initially treated as postembolisation syndrome, and analgesia was escalated. By the third day, pain was worsening and the woman developed marked tachypnoea and tachycardia, with raised inflammatory markers and lactate...
September 26, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28943978/impact-of-targeted-educational-interventions-on-appropriateness-of-stress-ulcer-prophylaxis-in-critically-ill-adults
#16
Drayton A Hammond, Catherine A Killingsworth, Jacob T Painter, Rose E Pennick, Kshitij Chatterjee, Bradley Boye, Nikhil Meena
BACKGROUND: Acid suppression therapy (AST) is routinely used in critically ill patients to prevent stress-related mucosal bleeding (SRMB). OBJECTIVE: Our objective was to determine the impact of a structured educational intervention on AST used for prevention of SRMB on appropriateness of AST. METHODS: A single-center, retrospective, cohort study of appropriate use of AST in critically ill patients admitted to the medical intensive care unit (ICU) at an academic medical center between January to June of 2014 (no intervention) and January to June of 2015 (intervention) was conducted...
July 2017: Pharmacy Practice
https://www.readbyqxmd.com/read/28943549/extramedullary-gastric-relapse-at-the-time-of-bone-marrow-relapse-of-acute-lymphoblastic-leukemia-after-allogeneic-bone-marrow-transplantation
#17
Kazuhiko Ikeuchi, Noriko Doki, Akinari Takao, Tsunekazu Hishima, Yuta Yamada, Tatsuya Konishi, Akihito Nagata, Toshiaki Takezaki, Satoshi Kaito, Shuhei Kurosawa, Masahiro Sakaguchi, Kaito Harada, Shunichiro Yasuda, Kosuke Yoshioka, Kyoko Watakabe-Inamoto, Aiko Igarashi, Yuho Najima, Hideharu Muto, Takeshi Kobayashi, Kazuhiko Kakihana, Hisashi Sakamaki, Kazuteru Ohashi
Extramedullary relapse (EMR) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is relatively rare. The most commonly reported sites in acute lymphoblastic leukemia (ALL) patients after allo-HSCT are soft tissue and the central nervous system, and the gastrointestinal system is an uncommon site. We herein report a unique case with massive hematemesis resulting from gastrointestinal relapse of ALL after allo-HSCT. Upper gastrointestinal endoscopy showed bleeding from a 1.5-cm submucosal tumorous lesion with central ulceration on the anterior wall of the stomach...
September 25, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28935474/superselective-embolization-for-arterial-upper-gastrointestinal-bleeding-using-n-butyl-cyanoacrylate-a-single-center-experience-in-152-patients
#18
Saebeom Hur, Hwan Jun Jae, Hyukjoon Lee, Myungsu Lee, Hyo-Cheol Kim, Jin Wook Chung
PURPOSE: To evaluate 30-day safety and efficacy of superselective embolization for arterial upper gastrointestinal bleeding (UGIB) using N-butyl cyanoacrylate (NBCA). MATERIALS AND METHODS: This single-center retrospective 10-year study included 152 consecutive patients with UGIB (gastric, n = 74; duodenal, n = 78) who underwent embolization with NBCA for angiographically positive arterial bleeding. The primary endpoint was clinical success rate defined as achievement of hemostasis without rebleeding or UGIB-related mortality within 30 days after embolization...
September 19, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28935445/-usefulness-of-small-bowel-capsule-endoscopy-in-gastrointestinal-bleeding
#19
Chloé Leandri, Benoit Bordacahar, Sophie Ribiere, Ammar Oudjit, Marie-Anne Guillaumot, Bertrand Brieau, Frédéric Prat, Vered Abitbol, Stanislas Chaussade, Romain Coriat
In France, upper gastrointestinal haemorrhages have an estimated annual incidence of 143 cases per 100,000 inhabitants. Classically, two types of digestive hemorrhage are described: acute and chronic digestive hemorrhages. Upper endoscopy is carried out in case of hematemesis or melena. It requires that the patient has been fasting for at least 6hours for solids and 3hours for liquids. The main etiologies of hemorrhagic hemorrhage of the origin are the vascular abnormalities, inflammatory or drug-induced ulcerations, intestinal tumors, Meckel's diverticulum, and Dieulafoy ulcer...
September 18, 2017: La Presse Médicale
https://www.readbyqxmd.com/read/28932555/does-bioglue-contribute-to-anastomotic-pseudoaneurysm-after-thoracic-aortic-surgery
#20
Wei-Guo Ma, Bulat A Ziganshin, Chang-Fa Guo, Mohammad A Zafar, Richard S Sieller, Maryann Tranquilli, John A Elefteriades
BACKGROUND: Although bovine serum albumin-glutaraldehyde glue (BioGlue®) has been successfully used as a hemostatic adjunct in aortic surgical procedures, there are reports that it may lead to anastomotic pseudoaneurysm formation. We seek to examine if the use of BioGlue is associated with a high incidence of anastomotic pseudoaneurysm formation following surgical repair of thoracic aortic disease. METHODS: We reviewed the medical records and follow-up computed tomography (CT) scans of patients from 2001 to 2015 in whom BioGlue was used during surgical repair of thoracic aortic disease to detect postoperative anastomotic pseudoaneurysm formation...
August 2017: Journal of Thoracic Disease
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