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https://www.readbyqxmd.com/read/29755269/inflammatory-myofibroblastic-tumor-of-the-orbit-a-clinico-pathological-study-of-25-cases
#1
Diego Strianese, Fausto Tranfa, Marialuisa Finelli, Adriana Iuliano, Stefania Staibano, Giuseppe Mariniello
Background: Inflammatory myofibroblastic tumor (IMT) is a rare entity characterized by the presence of myofibroblasts and inflammatory cells within a fibrous stroma, which typically occurs in children or young adults. The IMT is considered generally a benign lesion, although about 20% of cases may experience recurrence, and most rarely develop metastasis. Herein, we present the largest series of primary orbital IMT ever reported. Patients and methods: The clinical records of 25 patients, collected between the 1995 and 2015, with biopsy-proven diagnosis of orbital IMT were retrospectively reviewed to determine demographic, clinical, radiologic and pathological features, management, and outcome...
January 2018: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/29710187/prevalence-and-severity-of-high-blood-pressure-among-children-based-on-the-2017-american-academy-of-pediatrics-guidelines
#2
Atul K Sharma, Daniel L Metzger, Celia J Rodd
Importance: Based on the new 2017 blood pressure guidelines, the prevalence of high blood pressure (BP) among adults has increased from 32% to 46%. Based on new norms and diagnostic thresholds that better align with adult definitions, new clinical practice guidelines were also published for children. The American Academy of Pediatrics clinical practice guidelines for the management of elevated BP in children replace the 2004 fourth report from the National, Heart, Lung, and Blood Institute...
April 23, 2018: JAMA Pediatrics
https://www.readbyqxmd.com/read/29705181/-natural-progression-of-premature-pubarche-and-underlying-diseases
#3
María Luisa Sancho Rodríguez, Gloria Bueno Lozano, José Ignacio Labarta Aizpún, Antonio de Arriba Muñoz
INTRODUCTION: Premature pubarche (PP) is generally thought to be a benign condition, but it can also be the first sign of underlying disease. OBJECTIVE: To analyse the aetiology and the evolution of the anthropometric, analytical and metabolic risk parameters of a group of patients with PP. MATERIAL AND METHODS: A descriptive and analytical retrospective study of 92 patients affected by PP. Anthropometry, analyses, bone age and indicators of lipid metabolism were all evaluated...
April 25, 2018: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/29680824/dash-score-and-subsequent-risk-of-coronary-artery-disease-the-findings-from-million-veteran-program
#4
Luc Djoussé, Yuk-Lam Ho, Xuan-Mai T Nguyen, David R Gagnon, Peter W F Wilson, Kelly Cho, J Michael Gaziano
BACKGROUND: While adherence to healthful dietary patterns has been associated with a lower risk of coronary artery disease (CAD) in the general population, limited data are available among US veterans. We tested the hypothesis that adherence to Dietary Approach to Stop Hypertension (DASH) food pattern is associated with a lower risk of developing CAD among veterans. METHODS AND RESULTS: We analyzed data on 153 802 participants of the Million Veteran Program enrolled between 2011 and 2016...
April 21, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29675756/nodular-macroregenerative-tissue-as-a-pattern-of-regeneration-in-cholangiopathic-disorders
#5
Preston Roberts, Andrew T Trout, Jonathan R Dillman
BACKGROUND: Published case series have described central hepatic macroregenerative nodules or masses as a common feature of Alagille syndrome. Our experience suggests this regenerative pattern can be seen more generally in cholangiopathic disorders. OBJECTIVE: To define the frequency of central regenerative tissue in Alagille syndrome and other cholangiopathic disorders and to describe the typical appearance of such regenerative tissue. MATERIALS AND METHODS: We conducted a retrospective study of CT and MR imaging performed in children and young adults with cholangiopathic disorders between January 2000 and June 2016...
April 19, 2018: Pediatric Radiology
https://www.readbyqxmd.com/read/29605025/fewer-thromboembolic-events-after-implementation-of-a-venous-thromboembolism-risk-stratification-tool
#6
Florence E Turrentine, Min-Woong Sohn, Susan L Wilson, Crockett Stanley, Wendy Novicoff, Robert G Sawyer, Michael D Williams
BACKGROUND: Deep venous thrombosis and pulmonary embolus are leading preventable causes of death after surgery. Venous thromboembolism (VTE) prophylaxis management guidelines, with evidenced-based recommendations, are available in the literature. However, over 40% of "at-risk" surgical patients fail to receive appropriate VTE prophylaxis. Decision support-based interventions to reduce venous thromboembolic events were explored. METHODS: A venous thromboembolic risk stratification tool embedded in the electronic medical record, Epic, linking risk category to venous thromboembolic prophylaxis order sets was created, implemented, and analyzed for general surgery patients...
May 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29577222/-establishment-of-comprehensive-prediction-model-of-acute-gastrointestinal-injury-classification-of-critically-ill-patients
#7
Yan Wang, Jianrong Wang, Weiwei Liu, Guangliang Zhang
OBJECTIVE: To develop the comprehensive prediction model of acute gastrointestinal injury (AGI) grades of critically ill patients. METHODS: From April 2015 to November 2015, the binary channel gastrointestinal sounds (GIS) monitor system which has been developed and verified by the research group was used to gather and analyze the GIS of 60 consecutive critically ill patients who were admitted in Critical Care Medicine of Chinese PLA General Hospital. Also, the AGI grades (Grande I(-IIII(, the higher the level, the heavier the gastrointestinal dysfunction) were evaluated...
March 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29564032/postmastectomy-breast-reconstruction-with-the-totally-autologous-latissimus-dorsi-flap-in-the-thin-small-breasted-woman-give-it-more-thought
#8
Fawz Kazzazi, Rosanna C Ching, Charles M Malata
Introduction: Thin women have fewer autologous tissue breast reconstructive options than their higher body mass index counterparts-due to a lack of adequate donor sites. They are therefore usually offered expander/implant techniques. The total autologous latissimus dorsi flap is generally used in "well-padded" individuals, as they have enough fat on their back on which a completely autologous reconstruction could be based. When implant-based reconstruction is contraindicated (for instance due to planned adjuvant radiotherapy) or unacceptable to the patient, the total autologous latissimus dorsi flap can provide adequate tissue volume by utilizing the additional back fat deposits even in the thin, small-breasted patient...
2018: Eplasty
https://www.readbyqxmd.com/read/29506824/single-site-robotic-cholecystectomy-and-robotics-training-should-we-start-in-the-junior-years
#9
Reed I Ayabe, Aaron B Parrish, Christine E Dauphine, Danielle M Hari, Junko J Ozao-Choy
BACKGROUND: It has become increasingly important to expose surgical residents to robotic surgery as its applications continue to expand. Single-site robotic cholecystectomy (SSRC) is an excellent introductory case to robotics. Resident involvement in SSRC is known to be feasible. Here, we sought to determine whether it is safe to introduce SSRC to junior residents. MATERIALS AND METHODS: A total of 98 SSRC cases were performed by general surgery residents between August 2015 and August 2016...
April 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29490971/sex-differences-in-the-association-between-measures-of-general-and-central-adiposity-and-the-risk-of-myocardial-infarction-results-from-the-uk-biobank
#10
Sanne A E Peters, Sophie H Bots, Mark Woodward
BACKGROUND: There are substantial differences in the distribution of adipose tissue between women and men. We assessed the sex-specific relationships and their differences between measures of general and central adiposity and the risk of incident myocardial infarction (MI). METHODS AND RESULTS: Between 2006 and 2010, the UK Biobank recruited over 500 000 participants aged 40 to 69 years across the United Kingdom. During 7 years of follow-up, 5710 cases of MI (28% women) were recorded among 265 988 women and 213 622 men without a history of cardiovascular disease at baseline...
February 28, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29455347/a-prospective-comparative-study-of-hip-resurfacing-arthroplasty-and-large-diameter-head-metal-on-metal-total-hip-arthroplasty-in-younger-patients-a-minimum-of-five-year-follow-up
#11
Ran Tao, Fan Liu, Ya-Ke Liu, Yue Lu, Hua Xu, Yi Cao, Zhen-Yu Zhou, Wei Wang
INTRODUCTION: Both hip resurfacing arthroplasty (HRA) and large-diameter head metal-on-metal total hip arthroplasty (LDH MoM THA) are generally used for young and active patients. A number of comparative studies of HRA and total hip arthroplasty have been published in the literature. However, studies that have compared HRA with LDH MoM THA are rare. The purpose of this study is to compare the mid-term results of HRA with those of LDH MoM THA in young patients. PATIENTS AND METHODS: Between 2007 and 2011, 68 patients were enrolled in the study and randomized into two groups: HRA group (28 hips) and LDH MoM THA group (40 hips)...
February 18, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29422485/is-the-word-osteoporosis-a-reason-for-kinesiophobia
#12
Zafer Gunendi, Dilek Eker, Duygu Tecer, Belgin Karaoglan
BACKGROUND: Osteoporosis is a systemic skeletal disease that causes weakening of the bones which increases the risk of fractures. Especially hip fractures lead to substantial physical, psychological, social and economic burden both for the patients and the governments. Excercises and physically active life style are essential preventive and therapeutic approaches for osteoporosis. Kinesiophobia is an irrational fear of movement due to the belief of susceptibility to injury. It is associated with lower levels of physical activity...
February 7, 2018: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29344082/implementing-guidelines-on-physical-health-in-the-acute-mental-health-setting-a-quality-improvement-approach
#13
Stuart Green, Ed Beveridge, Liz Evans, Jenny Trite, Sandra Jayacodi, Rachel Evered, Caroline Parker, Luca Polledri, Emily Tabb, John Green, Anton Manickam, Joanna Williams, Rebecca Deere, Bill Tiplady
Background: In the UK, life expectancy for people living with a serious mental illness, such as schizophrenia and bipolar disorder, is reduced by 15-20 years compared with the general population. In recent years, evidence based guidelines/policies designed to improve their physical health have been published, yet a gap remains between recommendations and practice. This case study describes how guidelines to support physical health were implemented using a quality improvement approach...
2018: International Journal of Mental Health Systems
https://www.readbyqxmd.com/read/29335910/duration-and-magnitude-of-postoperative-risk-of-venous-thromboembolism-after-planned-inguinal-hernia-repair-in-men-a-population-based-cohort-study
#14
D J Humes, A Abdul-Sultan, A J Walker, J F Ludvigsson, J West
PURPOSE: Little is known regarding the magnitude and timing of the risk of VTE following inguinal hernia surgery. We aimed to determine the absolute and relative rates of venous thromboembolism (VTE) following planned inguinal hernia repair. METHODS: We analysed male adults with a first inguinal hernia repair with no prior record of VTE from the Clinical Practice Research Datalink, linked to the Hospital Episode Statistics (2001-2011). Crude rates and adjusted hazard ratios (HR) of the first VTE were calculated using Cox regression analysis to compare specific time periods following the surgery compared to the general population...
January 15, 2018: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/29331994/acl-and-meniscal-injuries-increase-the-risk-of-primary-total-knee-replacement-for-osteoarthritis-a-matched-case-control-study-using-the-clinical-practice-research-datalink-cprd
#15
Tanvir Khan, Abtin Alvand, Daniel Prieto-Alhambra, David J Culliford, Andrew Judge, William F Jackson, Brigitte E Scammell, Nigel K Arden, Andrew James Price
OBJECTIVES: The aim of this study was to investigate whether ACL injury (ACLi) or meniscal injury increases the risk of end-stage osteoarthritis (OA) resulting in total knee replacement (TKR). METHODS: A matched case-control study of all TKRs performed in the UK between January 1990 and July 2011 and recorded in the Clinical Practice Research Datalink (CPRD) was undertaken. The CPRD contains longitudinal data on approximately 3.6 million patients. Two controls were selected for each case of TKR, matched on age, sex and general practitioner location as a proxy for socioeconomic status...
January 13, 2018: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/29305685/frontoethmoidal-encephalocele-clinical-presentation-diagnosis-treatment-and-complications-in-400-cases
#16
Muhammad Arifin, Wihasto Suryaningtyas, Abdul Hafid Bajamal
PURPOSE: The purpose of this study is to review a large series of frontoethmoidal encephalocele (FEE) regarding their clinical presentation, the progressiveness of the mass volume, the skin stigmata as well as its surgical approach and post-surgical complications. METHOD: Records of all FEE patients treated in Soetomo General Hospital, Surabaya, and Charity Foundation Program from 2008 to 2015 were reviewed. Detailed patient's demography, clinical findings, radiology results, operative procedures, and complications were documented...
January 5, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29297977/the-association-between-idiopathic-thrombocytopenic-purpura-and-cardiovascular-disease-a-retrospective-cohort-study
#17
J S Chandan, T Thomas, S Lee, T Marshall, B Willis, K Nirantharakumar, P Gill
Essentials We estimated the cardiovascular risk of patients with idiopathic thrombocytopenic purpura (ITP). The risk of cardiovascular disease was 38% higher in ITP patients compared with controls. Among the ITP patients, splenectomy was associated with higher cardiovascular disease. Clinicians should consider cardiovascular risk when managing ITP patients. SUMMARY: Background Idiopathic thrombocytopenic purpura (ITP) is classically characterized by a transient or persistent decrease of platelet count...
March 2018: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/29228958/sero-prevalence-risk-factors-and-distribution-of-sheep-and-goat-pox-in-amhara-region-ethiopia
#18
Tsegaw Fentie, Nigusie Fenta, Samson Leta, Wassie Molla, Birhanu Ayele, Yechale Teshome, Seleshe Nigatu, Ashenafi Assefa
BACKGROUND: Sheep pox and goat pox are contagious viral diseases of sheep and goats, respectively. The diseases result in substantial economic losses due to decreased milk and meat production, damage to hides and wool, and possible trade restriction. A study was undertaken in Amhara region of Ethiopia. A cross-sectional study design was used to estimate the sero-prevalence and identify associated risk factors, while retrospective study design was used to assess the temporal and spatial distribution of the disease...
December 11, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29158232/development-and-validation-of-qdiabetes-2018-risk-prediction-algorithm-to-estimate-future-risk-of-type-2-diabetes-cohort-study
#19
Julia Hippisley-Cox, Carol Coupland
Objectives  To derive and validate updated QDiabetes-2018 prediction algorithms to estimate the 10 year risk of type 2 diabetes in men and women, taking account of potential new risk factors, and to compare their performance with current approaches. Design  Prospective open cohort study. Setting  Routinely collected data from 1457 general practices in England contributing to the QResearch database: 1094 were used to develop the scores and a separate set of 363 were used to validate the scores. Participants  11...
November 20, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29156253/exploring-the-impact-of-using-measured-or-estimated-values-for-height-and-weight-on-the-relationship-between-bmi-and-acute-hospital-mortality
#20
Anne P Toft-Petersen, Jerome Wulff, David A Harrison, Marlies Ostermann, Mike Margarson, Kathryn M Rowan, Deborah Dawson
PURPOSE: Studies have demonstrated an association between height and weight and mortality among patients in the Intensive Care Unit (ICU) and the optimal body mass index (BMI) might be well above the optimal values in the general population. Most of these studies have relied on estimated values, the validity of which is not known. MATERIAL AND METHODS: Admissions to adult general ICUs from 1 April 2009 to 31 March 2016 in the Case Mix Programme (CMP) Database were described by height and weight assessment methods (measured or estimated)...
April 2018: Journal of Critical Care
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