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Heart valves endocarditis

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https://www.readbyqxmd.com/read/28443984/antifungal-activity-of-caspofungin-in-experimental-infective-endocarditis-caused-by-candida-albicans
#1
Gerardo Becerra Victorio, Lorena Michele Brennan Bourdon, Leonel García Benavides, Selene G Huerta-Olvera, Arturo Plascencia, José Villanueva, Erika Martinez-Lopez, Iván Isidro Hernández-Cañaveral
BACKGROUND: Infective endocarditis is a disease characterised by heart valve lesions, which exhibit extracellular matrix proteins that act as a physical barrier to prevent the passage of antimicrobial agents. The genus Candida has acquired clinical importance given that it is increasingly being isolated from cases of nosocomial infections. OBJECTIVE: To evaluate the activity of caspofungin compared to that of liposomal amphotericin B against Candida albicans in experimental infective endocarditis...
May 2017: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/28417489/management-of-septic-emboli-in-patients-with-infectious-endocarditis
#2
Seyed Hossein Aalaei-Andabili, Tomas Martin, Phillip Hess, Brian Hoh, Meshka Anderson, Charles T Klodell, Thomas M Beaver
BACKGROUND AND AIM: Septic emboli (SE) associated with infectious endocarditis (IE) can result in splenic abscesses and infectious intracranial aneurysms (IIA). We investigated the impact of SE on patient outcomes following surgery for IE. METHOD: From January-2000 to October-2015, all patients with surgical IE (n = 437) were evaluated for incidence and management of SE. RESULTS: Overall SE was found in 46/437 (10.52%) patients (n = 17 spleen, 13 brain, and 16 both)...
April 17, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28415082/p210long-term-outcome-of-primary-mitral-valve-prolapse-results-from-a-population-of-250-patients-referred-to-a-tertiary-cardiovascular-center
#3
V Mecarocci, F Mori
Background: Outcome of Mitral Valve Prolapse (MVP) was controversial for long time. Many studies reported great differences in the incidence of cardiovascular events due, above all, to heterogeneous and small studied populations. Most of theme were also published to late '80 of the last century till early '00. Purpose: To make a contemporary survey on the incidence of cardiovascular events in a selected population of patients affected by primary MVP referred to a tertiary cardiovascular center for the medical and surgical care of valvular heart disease...
December 1, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28414678/what-the-eyes-don-t-see-the-heart-does-grieve-over
#4
M Sciaudone, M Dery
INTRODUCTION: A 71 year old Peruvian woman presented with blurry vision and bilateral eye pain and had evidence of bilateral endophthalmitis on eye examination. Her past medical history was notable for multiple abdominal surgeries within the preceding months, including an incarcerated inguinal hernia repair which required an ileostomy placement, and cholecystitis requiring cholecystostomy tube placement. Over her multiple long hospitalizations, she developed bacteremia and fungemia on several occasions, with organisms including Enterobacter cloacae, Klebsiella pneumoniae, Bacteroides fragilis, Pseudomonas aeruginosa, Enterococcus faecium, and Candida albicans...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28414664/gonococcal-endocarditis-the-gift-that-stops-giving-an-uncommon-presentation-of-a-common-disease
#5
G Olayemi, M Oferczak, A Elagizi, I El-Abbassi, M Eschete, J Crowe
INTRODUCTION: Gonorrhea is the 2nd most common sexually transmitted disease in the US with 800,000 cases of gonorrhea each year. Disseminated gonorrhea infection occurs in 0.5 percent - 3 percent of these patients and is more frequent in woman younger than 40 years of age. CASE: A 36 year old woman with a history of polysubstance abuse presented with 10 day history of feeling generally unwell. At presentation, vitals were remarkable for tachycardia and hypotension...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28410379/new-insights-into-valve-related-intramural-and-intracellular-bacterial-diversity-in-infective-endocarditis
#6
Andreas Oberbach, Nadine Schlichting, Stefan Feder, Stefanie Lehmann, Yvonne Kullnick, Tilo Buschmann, Conny Blumert, Friedemann Horn, Jochen Neuhaus, Ralph Neujahr, Erik Bagaev, Christian Hagl, Maximilian Pichlmaier, Arne Christian Rodloff, Sandra Gräber, Katharina Kirsch, Marcus Sandri, Vivek Kumbhari, Armirhossein Behzadi, Amirali Behzadi, Joao Carlos Correia, Friedrich Wilhelm Mohr, Maik Friedrich
AIMS: In infective endocarditis (IE), a severe inflammatory disease of the endocardium with an unchanged incidence and mortality rate over the past decades, only 1% of the cases have been described as polymicrobial infections based on microbiological approaches. The aim of this study was to identify potential biodiversity of bacterial species from infected native and prosthetic valves. Furthermore, we compared the ultrastructural micro-environments to detect the localization and distribution patterns of pathogens in IE...
2017: PloS One
https://www.readbyqxmd.com/read/28407841/cardiovascular-comorbidity-in-inflammatory-rheumatological-conditions
#7
Jürgen Braun, Klaus Krüger, Bernhard Manger, Matthias Schneider, Christof Specker, Hans Joachim Trappe
BACKGROUND: Approximately 1.5 million adults in Germany suffer from an inflammatory rheumatological condition. The most common among these are rheumatoid arthritis and spondyloarthritis-above all axial spondyloarthritis, including ankylosing spondylitis (Bekhterev's disease) and psoriatic arthritis. These systemic inflammatory diseases often affect the heart as well. METHODS: This review is based on pertinent articles retrieved by a selective literature search, on current European guidelines, and on the authors' clinical experience...
March 24, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/28405096/cardiac-rehabilitation-for-a-skydiver-after-aortic-valve-replacement-for-pure-aortic-regurgitation-and-resection-of-the-ascending-aorta-complicated-by-active-infective-endocarditis-and-heart-block-requiring-a-pacemaker
#8
Tonja R Solomon, Sandra DeJong, Tim Bilbrey, Pasquale Carbone, Mark Campbell, Robert D Parker, Alessandra Lira, Diogo Amarante, Jeffrey M Schussler, Jenny Adams
A professional skydiver underwent aortic valve and ascending aorta replacement complicated by infective endocarditis with root abscess and pacemaker implantation. He then enrolled in the Baylor Heart and Vascular Hospital cardiac rehabilitation (CR) program as part of its specificity of testing and exercise training facility. He performed specific skydiving cardiovascular and muscular strength tests at the beginning and the end of the CR program. His pacemaker was interrogated to ascertain any arrhythmias or lead displacement over the course of the CR program...
April 2017: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/28403058/multiorgan-involvement-confounding-the-diagnosis-of-bartonella-henselae-infective-endocarditis-in-children-with-congenital-heart-disease
#9
Christopher P Ouellette, Sarita Joshi, Karen Texter, Preeti Jaggi
Two children with congenital heart disease status post surgical correction presented with prolonged constitutional symptoms, hepatosplenomegaly and pancytopenia. Concern for malignancy prompted bone marrow biopsies that were without evidence thereof. In case 1, echocardiography identified a multilobulated vegetation on the conduit valve. In case 2, transthoracic, transesophageal and intracardiac echocardiography were performed and were without evidence of cardiac vegetations; however, pulmonic emboli raised concern for infective endocarditis...
May 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28390740/a-predictive-model-for-early-mortality-after-surgical-treatment-of-heart-valve-or-prosthesis-infective-endocarditis-the-endoscore
#10
Michele Di Mauro, Guglielmo Mario Actis Dato, Fabio Barili, Sandro Gelsomino, Pasquale Santè, Alessandro Della Corte, Antonio Carrozza, Ester Della Ratta, Diego Cugola, Lorenzo Galletti, Roger Devotini, Riccardo Casabona, Francesco Santini, Antonio Salsano, Roberto Scrofani, Carlo Antona, Luca Botta, Claudio Russo, Samuel Mancuso, Mauro Rinaldi, Carlo De Vincentiis, Andrea Biondi, Cesare Beghi, Giangiuseppe Cappabianca, Vincenzo Tarzia, Gino Gerosa, Michele De Bonis, Alberto Pozzoli, Francesco Nicolini, Filippo Benassi, Francesco Rosato, Elena Grasso, Ugolino Livi, Sponga Sandro, Davide Pacini, Roberto Di Bartolomeo, Andrea De Martino, Uberto Bortolotti, Francesco Onorati, Giuseppe Faggian, Roberto Lorusso, Enrico Vizzardi, Gabriele Di Giammarco, Daniele Marinelli, Emmanuel Villa, Giovanni Troise, Marco Picichè, Francesco Musumeci, Domenico Paparella, Vito Margari, Francesco Tritto, Girolamo Damiani, Giuseppe Scrascia, Salvatore Zaccaria, Attilio Renzulli, Giuseppe Serraino, Giovanni Mariscalco, Daniele Maselli, Massimiliano Foschi, Alessandro Parolari, Giannantonio Nappi
BACKGROUND: The aim of this large retrospective study was to provide a logistic risk model along an additive score to predict early mortality after surgical treatment of patients with heart valve or prosthesis infective endocarditis (IE). METHODS: From 2000 to 2015, 2715 patients with native valve endocarditis (NVE) or prosthesis valve endocarditis (PVE) were operated on in 26 Italian Cardiac Surgery Centers. The relationship between early mortality and covariates was evaluated with logistic mixed effect models...
April 4, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28390684/comparison-of-outcome-of-possible-versus-definite-infective-endocarditis-involving-native-heart-valves
#11
Lauriane Pericart, Anne Bernard, Thierry Bourguignon, Louis Bernard, Denis Angoulvant, Nicolas Clementy, Dominique Babuty, Laurent Fauchier
There are very few data on the prognosis of possible versus definite infective endocarditis (IE). We studied data from 365 consecutive patients with IE involving native heart valve seen in an academic institution from 1990 to 2012. Patients were classified according to the modified Duke criteria for IE: patients with possible IE (n = 101, 28%) and those with definite IE (n = 264, 72%). Patients with possible IE were older than those with definite IE (66 ± 15 vs 62 ± 16, p = 0.05). A causative microorganism was identified in 66% of patients with possible IE versus all patients with definite IE (p <0...
March 16, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28373788/infective-endocarditis-with-atypical-clinical-feature-and-relapse-by-abiotrophia-defectiva
#12
Ilkay Bozkurt, Metin Coksevim, Idris Bugra Cerik, Okan Gulel, Esra Tanyel, Hakan Leblebicioglu
A case of infective endocarditis caused by an uncommon agent Abiotrophia defectiva with atypical manifestations is presented. A 42-year-old woman previously had rheumatic heart disease, presented with the symptoms of fever and chills that resolved within 3 days under antibiotherapy. She was diagnosed with endocarditis due to A. defectiva. Despite culture-directed antibiotics being administered in the first admission, her symptoms and also blood culture growth relapsed 3 weeks later. She was successfully treated with antimicrobial therapy and surgical intervention including aorta and mitral valve replacement...
April 2017: Journal of the Saudi Heart Association
https://www.readbyqxmd.com/read/28372481/staphylococcal-versus-streptococcal-infective-endocarditis-in-a-tertiary-hospital-in-belgium-epidemiology-clinical-characteristics-and-outcome
#13
Jean Cyr Yombi, Sandra Nyota Yuma, Agnes Pasquet, Parla Astarci, Annie Robert, Hector Villalobos Rodriguez
Infective endocarditis (IE) is a rare but serious illness associated with a high mortality. Staphylococcus spp and Streptococcus spp are the most frequent causative pathogens. In this study, we compared the epidemiology, clinical characteristics and outcomes of patients with Staphylococcal and Streptococcal IE in a tertiary hospital. Using our institutional database 'Medical Explorer', we collected all cases of IE retrospectively between January 2005 and December 2010 at the Cliniques Universitaires Saint Luc and then focused on Staphylococcal and Streptococcal IE...
April 4, 2017: Acta Clinica Belgica
https://www.readbyqxmd.com/read/28369288/rapid-deployment-aortic-valve-replacement-for-severe-aortic-stenosis-1-year-outcomes-in-150-patients%C3%A2
#14
Alexis Theron, Eleonore Ravis, Dominique Grisoli, Nicolas Jaussaud, Pierre Morera, Pascal Candolfi, Jana Boleckova, David Lagier, Cecile Amanatiou, Lyna Messous, Vlad Gariboldi, Frederic Collart
OBJECTIVES: This study aimed to evaluate the safety and effectiveness of rapid-deployment aortic valve replacement (RDAVR) for severe aortic stenosis (AS). METHODS: All consecutive patients with severe AS who underwent RDAVR with the EDWARDS INTUITY bioprosthesis were prospectively included in a single-centre, cohort study between July 2012 and April 2015. Clinical examination and transthoracic echocardiography were performed preoperatively and at 1-month and 1-year follow-up...
March 23, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28365430/old-antimicrobials-and-gram-positive-cocci-through-the-example-of-infective-endocarditis-and-bone-and-joint-infections
#15
Piseth Seng, Sophie Amrane, Matthieu Million, Andreas Stein
The management of some serious infections such as infective endocarditis (IE) and bone and joint infections (BJIs) caused by Gram-positive cocci (GPC) is complex and requires great responsiveness and effective antimicrobials with high bioavailability in heart valves or bone tissues. Treatment of these infections requires the use of a higher dosage that may result in increased toxicity or the use of new promising antimicrobials to control the infection. However, use of these new antimicrobials could still bring about new toxicity and resistance...
March 29, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28348945/infective-endocarditis-in-a-patient-with-celiac-disease-after-central-venous-catheter-insertion
#16
Murtaza Sundhu, Suryanarayan Mohapatra, Salome Arobelidze, Parveen Gundelly, Anil Kumar Changarath Vijayan
There is an increasing incidence of infective endocarditis secondary to central venous catheters, which is termed as 'healthcare-associated infective endocarditis'. There is an increased risk of getting infective endocarditis in conditions with malnutrition and also if the tip of the central venous catheter is deep in the right atrium close to the tricuspid valve. We present a case of 31-year-old female who had all these risk factors. She was admitted to the hospital for the work up of the weight loss and was diagnosed with celiac disease...
February 13, 2017: Curēus
https://www.readbyqxmd.com/read/28344611/percutaneous-pulmonary-valve-implantation-state-of-the-art-and-polish-experience
#17
REVIEW
Elżbieta K Biernacka, Witold Rużyłło, Marcin Demkow
Percutaneous pulmonary valve implantation (PPVI) is a relatively new method of treating patients with right ventricular outflow tract (RVOT) dysfunction after surgical repair of congenital heart disease. Since its introduction in 2000 by Bonhoeffer, more than ten thousand PPVI procedures have been performed worldwide. Indications for PPVI have been adapted from those accepted for surgical intervention. Two types of valves are being used: Melody Medtronic available in diameters 16 mm and 18 mm and the family of Edwards SAPIEN valves 23, 26 and 29...
2017: Postępy W Kardiologii Interwencyjnej, Advances in Interventional Cardiology
https://www.readbyqxmd.com/read/28341191/-bacillus-cereus-endocarditis-and-a-probable-cutaneous-gateway
#18
S Soudet, C Becquart, F Dezoteux, K Faure, D Staumont-Salle, E Delaporte
BACKGROUND: Bacillus cereus is a ubiquitous telluric organism. B. cereus endocarditis is a rare condition seen mostly in prosthetic heart valves and among intravenous drug users. We report a new case of a patient without risk factors and with a good clinical outcome not requiring valve replacement. CASE REPORT: In October 2014, a 50-year-old woman was referred to the dermatology department of Lille University Hospital for lower-limb wounds developing 6 months earlier...
January 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/28335795/gemella-morbillorum-endocarditis-of-pulmonary-valve-a-case-report
#19
Dan Li, Zhicheng Zhu, Xiaomei Zheng, Weitie Wang, Rihao Xu, Kexiang Liu
BACKGROUND: Pulmonary valve infective endocarditis is a rare finding for endocarditis. Infective endocarditis caused by Gemella morbillorum remains a scanty occurrence. CASE PRESENTATION: This is a case reported of a 28-year-old Chinese male with endocarditis caused by pulmonary valve infection of Gemella morbillorum associated with congenital ventricular septal defect, atrial septal defect and double-chambered right ventricle. The patient presented with fever, shortness of breath, progressively worsening exertional fatigue, dyspnea and weight loss for 3 months...
March 23, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28335676/physiopathological-approach-to-infective-endocarditis-in-chronic-hemodialysis-patients-left-heart-versus-right-heart-involvement
#20
Yassamine Bentata
Infectious endocarditis (IE), a complication that is both cardiac and infectious, occurs frequently and is associated with a heavy burden of morbidity and mortality in chronic hemodialysis patients (CHD). About 2-6% of chronic hemodialysis patients develop IE and the incidence is 50-60 times higher among CHD patients than in the general population. The left heart is the most frequent location of IE in CHD and the different published series report a prevalence of left valve involvement varying from 80% to 100%...
November 2017: Renal Failure
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