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https://www.readbyqxmd.com/read/29352419/a-systematic-review-of-interventions-to-follow-up-test-results-pending-at-discharge
#1
Patrick J Darragh, T Bodley, A Orchanian-Cheff, K G Shojania, J L Kwan, P Cram
BACKGROUND: Patients are frequently discharged from the hospital before all test results have been finalized. Thirty to 40% of tests pending at discharge (TPADs) return potentially actionable results that could necessitate change in the patients' management, often unbeknownst to their physicians. Delayed follow-up of TPADs can lead to patient harm. We sought to synthesize the existing literature on interventions intended to improve the management of TPADs, including interventions designed to enhance documentation of TPADs, increase physician awareness when TPAD results finalize post-discharge, decrease adverse events related to missed TPADs, and increase physician satisfaction with TPAD management...
January 19, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29351117/associations-of-comorbid-anxiety-with-medication-adherence-and-psychiatric-symptomatology-in-a-population-of-nonadherent-bipolar-disorder-subjects
#2
Awais Aftab, Jennifer Levin, Michelle Aebi, Chetan Bhat, Martha Sajatovic
This analysis was conducted on baseline data from 178 nonadherent bipolar disorder subjects in a randomized controlled trial. Medication adherence was measured with Tablets Routine Questionnaire as percentage of days with missed doses. Inclusion criteria required at least 20% nonadherence. Medication adherence, symptomatology, and functioning in individuals with and without a comorbid anxiety disorder were compared. There were 78.9% of subjects who had at least one or more current anxiety disorder, with the most common being posttraumatic stress disorder, panic disorder, and generalized anxiety disorder...
January 19, 2018: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/29341066/cerebral-near-infrared-spectroscopy-nirs-for-perioperative-monitoring-of-brain-oxygenation-in-children-and-adults
#3
REVIEW
Yun Yu, Kaiying Zhang, Ling Zhang, Huantao Zong, Lingzhong Meng, Ruquan Han
BACKGROUND: Various techniques have been employed for the early detection of perioperative cerebral ischaemia and hypoxia. Cerebral near-infrared spectroscopy (NIRS) is increasingly used in this clinical scenario to monitor brain oxygenation. However, it is unknown whether perioperative cerebral NIRS monitoring and the subsequent treatment strategies are of benefit to patients. OBJECTIVES: To assess the effects of perioperative cerebral NIRS monitoring and corresponding treatment strategies in adults and children, compared with blinded or no cerebral oxygenation monitoring, or cerebral oxygenation monitoring based on non-NIRS technologies, on the detection of cerebral oxygen desaturation events (CDEs), neurological outcomes, non-neurological outcomes and socioeconomic impact (including cost of hospitalization and length of hospital stay)...
January 17, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29331095/household-food-insecurity-and-its-association-with-morbidity-report-among-school-adolescent-in-jimma-zone-ethiopia
#4
Dessalegn Tamiru, Tefera Belachew
Background Household food insecurity has a substantial contribution to poor health outcomes among young children and adolescents. Food insecurity also affects optimal cognitive development and physiological function of these vulnerable groups. There is a gap of documented data regarding the association of food insecurity and morbidity among school adolescents in Ethiopia. Objective The aim of this study is to assess the interrelationship of household food insecurity and morbidity report among school adolescent in Jimma zone, Ethiopia...
January 13, 2018: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/29330539/missing-value-imputation-approach-for-mass-spectrometry-based-metabolomics-data
#5
Runmin Wei, Jingye Wang, Mingming Su, Erik Jia, Shaoqiu Chen, Tianlu Chen, Yan Ni
Missing values exist widely in mass-spectrometry (MS) based metabolomics data. Various methods have been applied for handling missing values, but the selection can significantly affect following data analyses. Typically, there are three types of missing values, missing not at random (MNAR), missing at random (MAR), and missing completely at random (MCAR). Our study comprehensively compared eight imputation methods (zero, half minimum (HM), mean, median, random forest (RF), singular value decomposition (SVD), k-nearest neighbors (kNN), and quantile regression imputation of left-censored data (QRILC)) for different types of missing values using four metabolomics datasets...
January 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29329179/should-asymptomatic-men-who-have-sex-with-men-be-screened-for-oropharyngeal-chlamydia-clinical-outcomes-from-a-cross-sectional-study
#6
Jason J Ong, Eric P F Chow, Vesna De Petra, Deborah Williamson, Irene Pelatosis, Ben Howden, Lei Zhang, Marcus Y Chen, Catriona S Bradshaw, Jane Hocking, Christopher K Fairley
OBJECTIVE: To help inform screening guidelines, we estimated the proportion of asymptomatic men who have sex with men (MSM) with oropharyngeal chlamydia. STUDY DESIGN: An audit of asymptomatic MSM attending a sexual health service from March 2015 to April 2016 was conducted. They each had an oropharyngeal swab that was tested for Chlamydia trachomatis by transcription-mediated nucleic acid amplification. In addition, a random sample of 17 swabs that initially tested positive had confirmatory testing to determine the likelihood of true positivity...
February 2018: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29322594/rasagiline-improves-polysomnographic-sleep-parameters-in-patients-with-parkinson-s-disease-a-double-blind-baseline-controlled-trial
#7
Wiebke Schrempf, Mareike Fauser, Miriam Wienecke, Sebastian Brown, Antonia Maaß, Christiana Ossig, Karolin Otto, Moritz D Brandt, Matthias Löhle, Uta Schwanebeck, Xina Graehlert, Heinz Reichmann, Alexander Storch
OBJECTIVE: To study the effects of rasagiline on sleep quality in Parkinson's disease (PD) patients with sleep disturbances. INTRODUCTION: Sleep disorders are common in PD. Rasagiline is widely used in PD patients, but double-blind polysomnographic trials on its effects on sleep disturbances are missing. METHODS: Single-center, double-blind, baseline-controlled investigator-initiated clinical trial of rasagiline 1 mg/day over 8 weeks in PD patients with sleep disturbances...
January 11, 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29321879/space-time-clusters-for-early-detection-of-grizzly-bear-predation
#8
Joseph Kermish-Wells, Alessandro Massolo, Gordon B Stenhouse, Terrence A Larsen, Marco Musiani
Accurate detection and classification of predation events is important to determine predation and consumption rates by predators. However, obtaining this information for large predators is constrained by the speed at which carcasses disappear and the cost of field data collection. To accurately detect predation events, researchers have used GPS collar technology combined with targeted site visits. However, kill sites are often investigated well after the predation event due to limited data retrieval options on GPS collars (VHF or UHF downloading) and to ensure crew safety when working with large predators...
January 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29315168/novel-methods-for-reporting-of-exercise-dose-and-adherence-an-exploratory-analysis
#9
Tormod S Nilsen, Jessica M Scott, Meghan Michalski, Catherine Capaci, Samantha Thomas, James E Herndonx, John Sasso, Neil D Eves, Lee W Jones
PURPOSE: To explore whether methods adapted from oncology pharmacological trials have utility in reporting adherence (tolerability) of exercise treatment in cancer. METHODS: Using a retrospective analysis of a randomized trial, 25 prostate cancer patients received an aerobic training regimen of 72 supervised treadmill walking sessions delivered thrice-weekly between 55% to 100% of exercise capacity for 24 consecutive weeks. Treatment adherence (tolerability) was assessed using conventional (lost to follow up (LTF) and attendance) and exploratory [e...
January 8, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29313873/the-value-of-incorporating-personally-relevant-stimuli-into-consciousness-assessment-with-the-coma-recovery-scale-revised-a-pilot-study
#10
Jonas Stenberg, Alison K Godbolt, Marika C Möller
OBJECTIVE: To explore whether the use of personally relevant stimuli, for some tasks in the Coma Recovery Scale - Revised (CRS-R), generates more responses in patients with prolonged disorders of consciousness compared with neutral stimuli. DESIGN: Multiple single-case design. SUBJECTS: Three patients with prolonged disorders of consciousness recruited from an inpatient department at a regional brain injury rehabilitation clinic in Stockholm, Sweden...
January 9, 2018: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29302316/can-cash-break-the-cycle-of-educational-risks-for-young-children-in-high-hiv-affected-communities-a-cross-sectional-study-in-south-africa-and-malawi
#11
Lorraine Sherr, Mark Tomlinson, Ana Macedo, Sarah Skeen, Imca Sifra Hensels, Lucie Dale Cluver
Background: Household cash grants are associated with beneficial outcomes; enhanced if provided in combination with care. Objectives: This study describes the impact of cash grants and parenting quality on 854 children aged 5-15 (South African and Malawi) on educational outcomes including enrolment, regular attendance, correct class for age and school progress (controlling for cognitive performance). Consecutive attenders at randomly selected Community based organisations were recruited...
December 2017: Journal of Global Health
https://www.readbyqxmd.com/read/29300814/body-mass-index-and-20-specific-cancers-re-analyses-of-dose-response-meta-analyses-of-observational-studies
#12
E K Choi, H B Park, K H Lee, J H Park, M Eisenhut, H J van der Vliet, G Kim, J I Shin
Background: Objectives were to provide an overview and understand the strength of evidence and extent of potential biases and validity of claimed associations between Body Mass Index (BMI) and risk of developing cancer. Methods: We performed an umbrella review and comprehensively re-analysed the data of dose-response meta-analyses on associations between BMI and risk of 20-specific cancers (bladder, brain, breast, colonic, rectal, endometrial, gallbladder, gastric, leukemia, liver, lung, melanoma, multiple myeloma, non-Hodgkins lymphoma, oesophagus, ovarian, pancreatic, prostate, renal, thyroid) by adding big data or missed individual studies...
December 28, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29298749/importance-of-active-participation-in-obesity-management-through-mobile-health-care-programs-substudy-of-a-randomized-controlled-trial
#13
Bumjo Oh, Ga-Hye Yi, Min Kyu Han, Jong Seung Kim, Chang Hee Lee, Belong Cho, Hee Cheol Kang
BACKGROUND: Due to the prevalence of the westernized dietary pattern and lack of physical activity, the numbers of overweight or obese individuals are increasing, resulting in a growing health burden because of various related diseases. A lifestyle modification approach has additional advantages compared with pharmacological therapies or bariatric surgery. In our randomized controlled trial conducted in 2015, we successfully used a ubiquitous health care (SmartCare) service for patients with metabolic syndrome to achieve a significant weight loss effect...
January 3, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29294986/individual-and-institutional-predictors-of-ipv-sv-screening-in-college-health-centers
#14
Melissa A Sutherland, Heidi Collins Fantasia, M Katherine Hutchinson, Jennifer Katz
Intimate partner violence (IPV) and sexual violence (SV) are significant public health issues for women, particularly for college women. IPV and SV have been associated with numerous adverse health consequences and involvement in unhealthy behaviors. Given the health risks and high rates of IPV/SV among college women, it is important to understand and promote screening in this population. The purpose of this study was to examine college women's experiences with IPV/SV screening at college health centers and identify individual and institutional characteristics associated with screening...
November 1, 2017: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29283207/hard-tissue-volume-stability-of-guided-bone-regeneration-during-the-healing-stage-in-the-anterior-maxilla-a-clinical-and-radiographic-study
#15
Xi Jiang, Yu Zhang, Ping Di, Ye Lin
BACKGROUND: Guided bone regeneration (GBR) is currently the most widely used technique to reconstruct localized peri-implant bone defects. OBJECTIVES: To evaluate hard tissue volume stability during the healing stage of GBR with particulate bone graft and resorbable collagen membrane. MATERIALS AND METHODS: Twenty-eight patients who were missing a single maxillary incisor and required implant placement combined with GBR were randomly assigned to 2 groups: submerged (n = 14) and transmucosal (n = 14) healing groups...
December 28, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29247102/influence-of-overstated-abstract-conclusions-on-clinicians-a-web-based-randomised-controlled-trial
#16
Kiyomi Shinohara, Takuya Aoki, Ryuhei So, Yasushi Tsujimoto, Aya M Suganuma, Morito Kise, Toshi A Furukawa
OBJECTIVES: To investigate whether overstatements in abstract conclusions influence primary care physicians' evaluations when they read reports of randomised controlled trials (RCTs) DESIGN: RCT setting: This study was a parallel-group randomised controlled survey, conducted online while masking the study hypothesis. PARTICIPANTS: Volunteers were recruited from members of the Japan Primary Care Association in January 2017. We sent email invitations to 7040 primary care physicians...
December 14, 2017: BMJ Open
https://www.readbyqxmd.com/read/29246883/causes-and-consequences-of-missing-health-related-quality-of-life-assessments-in-patients-who-undergo-mechanical-circulatory-support-implantation-insights-from-intermacs-interagency-registry-for-mechanically-assisted-circulatory-support
#17
REVIEW
Kathleen L Grady, Philip G Jones, Adin Cristian-Andrei, David C Naftel, Susan Myers, Mary Amanda Dew, Katharine Idrissi, Gerdi Weidner, Sherri A Wissman, James K Kirklin, John A Spertus
BACKGROUND: Missing health-related quality of life (HRQOL) data in longitudinal studies can reduce precision and power and bias results. Using INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support), we sought to identify factors associated with missing HRQOL data, examine the impact of these factors on estimated HRQOL assuming missing at random missingness, and perform sensitivity analyses to examine missing not at random (MNAR) missingness because of illness severity...
December 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/29243007/comparison-of-telephone-and-televideo-modes-for-delivery-of-genetic-counseling-a-randomized-trial
#18
Corrine I Voils, Vickie L Venne, Hollis Weidenbacher, Nina Sperber, Santanu Datta
Telephone and televideo have yielded equivalent patient satisfaction and psychosocial outcomes when compared to in-person genetic counseling, yet little is known about how they compare to one another. In this randomized controlled trial, veterans received genetic counseling via telephone or traveled to a clinic to participate via encrypted televideo. Knowledge and visit satisfaction were assessed 2 weeks later. Travel time, mileage, and out-of-pocket costs were calculated for videoconferencing. Qualitative interviews were conducted with patients and counselors to assess acceptability...
December 15, 2017: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/29239740/hyperthyroxinemia-is-positively-associated-with-prevalent-and-incident-type-2-diabetes-mellitus-in-two-population-based-samples-from-northeast-germany-and-denmark
#19
T Ittermann, S Schipf, M Dörr, B H Thuesen, T Jørgensen, H Völzke, M R P Markus
BACKGROUND AND AIMS: A potential causal relationship between thyroid function and type 2 diabetes mellitus is currently under debate, but the current state of research is limited. Our aim was to investigate the association of thyroid hormone levels with prevalent and incident type 2 diabetes mellitus (T2DM) in two representative studies. METHODS AND RESULTS: Analyses are based on data from the Study of Health in Pomerania (SHIP), a German population based cohort with 4308 individuals at baseline and 3300 individuals at a five-year follow-up, and from INTER99, a Danish population-based randomized controlled trial with 6784 individuals at baseline and 4516 individuals at the five-year-follow-up...
October 25, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29235664/an-observer-blinded-randomised-controlled-pilot-trial-comparing-localised-immersion-psoralen-ultraviolet-a-puva-with-localised-narrowband-ultraviolet-b-nbuvb-for-the-treatment-of-palmar-hand-eczema
#20
D Brass, T Fouweather, D D Stocken, C Macdonald, J Wilkinson, J Lloyd, P M Farr, N J Reynolds, P J Hampton
BACKGROUND: Hand eczema is a common inflammatory dermatosis that causes significant patient morbidity. Symptoms such as pain, itch and localised swelling contribute to disruption of activities of daily living, lack of sleep, and missed days from work. The aetiology is often multifactorial. Previous studies comparing psoralen ultraviolet A (PUVA) and narrowband ultraviolet B (NBUVB) have been small, non-randomised and retrospective. OBJECTIVES: To conduct an observer blinded randomized controlled pilot study using validated scoring criteria to compare immersion PUVA with NBUVB for the treatment of chronic hand eczema unresponsive to topical steroids...
December 13, 2017: British Journal of Dermatology
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