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https://www.readbyqxmd.com/read/28918412/prediction-of-early-unplanned-intensive-care-unit-readmission-in-a-uk-tertiary-care-hospital-a-cross-sectional-machine-learning-approach
#1
Thomas Desautels, Ritankar Das, Jacob Calvert, Monica Trivedi, Charlotte Summers, David J Wales, Ari Ercole
OBJECTIVES: Unplanned readmissions to the intensive care unit (ICU) are highly undesirable, increasing variance in care, making resource planning difficult and potentially increasing length of stay and mortality in some settings. Identifying patients who are likely to suffer unplanned ICU readmission could reduce the frequency of this adverse event. SETTING: A single academic, tertiary care hospital in the UK. PARTICIPANTS: A set of 3326 ICU episodes collected between October 2014 and August 2016...
September 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/28917644/alpps-as-a-salvage-procedure-after-insufficient-future-liver-remnant-hypertrophy-following-portal-vein-occlusion
#2
Marcelo Enne, Erik Schadde, Bergthór Björnsson, Roberto Hernandez Alejandro, Klaus Steinbruck, Eduardo Viana, Ricardo Robles Campos, Massimo Malago, Pierre-Alain Clavien, Eduardo De Santibanes, Brice Gayet
BACKGROUND: A minimum future liver remnant (FLR) of 30% is required to avoid post hepatectomy liver failure (PHLF). Portal vein occlusion (PVO) is the main strategy to induce hypertrophy of the FLR, but some patients will not reach sufficient FLR hypertrophy to enable resection. Recently ALPPS has emerged as a "Salvage Procedure" for PVO failure. The aim of this study was to report the short term outcomes of ALPPS following PVO failure. METHODS: A retrospective analysis of patients enrolled within the international ALPPS Registry between October 2012 and November 2015 (NCT01924741) was performed...
September 13, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28917602/comparing-inpatient-versus-outpatient-bowel-preparation-in-children-and-adolescents-undergoing-appendicovesicostomy
#3
David L Weatherly, Konrad M Szymanski, Benjamin M Whittam, William E Bennett, Shelly King, Rosalia Misseri, Martin Kaefer, Richard C Rink, Mark P Cain
PURPOSE: The need for mechanical inpatient bowel preparation (IBP) in reconstructive pediatric urology has come under scrutiny, secondary to literature demonstrating little benefit regarding outcomes. Starting in 2013, a majority of patients undergoing reconstructive procedures at our institution no longer underwent IBP. We hypothesized that outpatient bowel preparation (OBP) would reduce length of stay (LOS) without increasing postoperative complications after appendicovesicostomy surgery...
August 26, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28917197/adolescent-socioeconomic-status-and-depressive-symptoms-in-later-life-evidence-from-structural-equation-models
#4
Elizabeth C Pino, Karla Damus, Brian Jack, David Henderson, Snezana Milanovic, Bindu Kalesan
BACKGROUND: The complex association between socioeconomic status (SES) and depressive symptoms is not entirely understood and the existing literature does not address the relationship between early-life SES and later-life depression from a life-course perspective, incorporating mediating events. METHODS: Using data from the Wisconsin Longitudinal Study, we employed structural equation modeling to examine how SES measured at age 18 affects depressive symptoms at age 54 directly and through mediating variables college graduation, marriage, and household income level at age 36...
September 8, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28917063/accuracy-of-preoperative-fine-needle-aspiration-in-diagnosis-of-malignant-parotid-tumors
#5
Hani Z Marzouki, Mohammed A Altabsh, Mohammed O Albakrei, Talal A Al-Khatib, Mazin A Merdad, Nada J Farsi
To determine the diagnostic accuracy of fine needle aspiration (FNA) for detecting malignant parotid tumors. Methods: We conducted a retrospective study of all patients diagnosed with benign or malignant parotid gland tumors in King Abdulaziz University Hospital,  Jeddah, Saudi Arabia, between January 2004 and May 2015. The records of 65 subjects were obtained. Histopathological findings and data from FNA examinations were obtained from medical records. Twenty-three subjects were excluded due to missing FNA, histopathology results or both...
October 2017: Saudi Medical Journal
https://www.readbyqxmd.com/read/28916386/molecular-mechanisms-of-the-r61t-mutation-in-apolipoprotein-e4-a-dynamic-rescue
#6
Benfeard Williams, Marino Convertino, Jhuma Das, Nikolay V Dokholyan
The apolipoprotein E4 (ApoE4) gene is the strongest genetic risk factor for Alzheimer's disease (AD). With respect to the other common isoforms of this protein (ApoE2 and ApoE3), ApoE4 is characterized by lower stability that underlies the formation of a stable interaction between the protein's N- and C-terminal domains. AD-related cellular dysfunctions have been linked to this ApoE4 misfolded state. In this regard, it has been reported that the mutation R61T is able to rescue the deleterious cellular effects of ApoE4 by preventing the formation of the misfolded intermediate state...
September 12, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/28916272/external-validation-of-the-pathologic-nodal-staging-score-for-prostate-cancer-a%C3%A2-population-based-study
#7
Malte Rieken, Luis A Kluth, Christian Seitz, Mohammad Abufaraj, Beat Foerster, Romain Mathieu, Pierre I Karakiewicz, Alexander Bachmann, Alberto Briganti, Morgan Rouprê, Mithat Gönen, Shahrokh F Shariat, Veronika Seebacher
BACKGROUND: We sought to externally validate our pathologic nodal staging score (pNSS) model, which allows for quantification of the likelihood that a pathologically node-negative patient will not have lymph node (LN) metastasis after radical prostatectomy for prostate cancer (PCa) in a population-based cohort. PATIENTS AND METHODS: We analyzed data from 50,598 patients treated with radical prostatectomy and pelvic LN dissection using the Surveillance, Epidemiology, and End Results database...
August 24, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28915864/physical-fitness-and-anthropometric-characteristics-among-adolescents-living-in-urban-or-rural-areas-of-kosovo
#8
Faton Tishukaj, Ismet Shalaj, Masar Gjaka, Besim Ademi, Rrustem Ahmetxhekaj, Norbert Bachl, Harald Tschan, Barbara Wessner
BACKGROUND: High physical fitness levels in childhood and adolescence are associated with positive health-related outcomes later in life. Albeit many researchers investigated rural-urban differences in physical fitness, the outcomes of these studies are inconsistent and data on Kosovo are widely missing. Thus, this study aims to examine anthropometric and physical fitness parameters in 14 to 15 year old Kosovan adolescents living in rural and urban areas. METHODS: Two schools from Pristina (mostly urban population) and two schools in the surrounding villages of the district of Deçan (mostly rural population) were selected...
September 16, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28915847/absence-of-ultrasound-inflammation-in-patients-presenting-with-arthralgia-rules-out-the-development-of-arthritis
#9
Myrthe van der Ven, M van der Veer-Meerkerk, D F Ten Cate, N Rasappu, M R Kok, D Csakvari, J M W Hazes, A H Gerards, J J Luime
BACKGROUND: To decrease the burden of disease of rheumatoid arthritis (RA), patients at risk for RA need to be identified as early as possible, preferably when no clinically apparent synovitis can be detected. Up to now, it has been fairly difficult to identify those patients with arthralgia who develop inflammatory arthritis (IA), but recent studies using ultrasound (US) suggest that earlier detection is possible. We aimed to identify patients with arthralgia developing IA within 1 year using US to detect subclinical synovitis at first consultation...
September 15, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28915414/evaluation-of-surgical-decision-making-and-resulting-outcome-in-patients-with-highly-eloquent-glioblastoma-results-of-a-multicenter-assessment
#10
Jan Coburger, Mirjam Renovanz, Oliver Ganslandt, Florian Ringel, Christian Rainer Wirtz, Javier Segovia von Riehm
INTRODUCTION: Treatment of glioblastoma(GB) patients amenable only for a subtotal resection(STR) is controversial. Since outcome of patients is affected by surgical management, our aim was to assess surgical decision making and resulting outcome in patients with highly eloquent GBs. PATIENTS AND METHODS: We retrospectively assessed GB patients with intended sub-total resection (STR) or stereotactic biopsy (STX) of 3 neurooncological centers operated between 2008 and 2013...
September 8, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28915223/quality-measures-a-stakeholder-analysis
#11
Marianne Baernholdt, Nancy Dunton, Ronda G Hughes, Patricia W Stone, Kathleen M White
For quality measures, confusion and discontentment have increased, as availability of electronic data and data collection tools has expanded. We examined current issues with quality measures across 4 stakeholder groups: developers, regulators/endorsers, data collectors, and consumer advocates. There are missing quality measures, issues with data quality and purpose, questionable usability of electronic health records, and an increased measurement burden and cost. Policymakers, administrators, health care professionals, and consumers need to collaborate on measure development and selection...
September 14, 2017: Journal of Nursing Care Quality
https://www.readbyqxmd.com/read/28914787/a-sparse-dictionary-learning-based-adaptive-patch-inpainting-method-for-thick-clouds-removal-from-high-spatial-resolution-remote-sensing-imagery
#12
Fan Meng, Xiaomei Yang, Chenghu Zhou, Zhi Li
Cloud cover is inevitable in optical remote sensing (RS) imagery on account of the influence of observation conditions, which limits the availability of RS data. Therefore, it is of great significance to be able to reconstruct the cloud-contaminated ground information. This paper presents a sparse dictionary learning-based image inpainting method for adaptively recovering the missing information corrupted by thick clouds patch-by-patch. A feature dictionary was learned from exemplars in the cloud-free regions, which was later utilized to infer the missing patches via sparse representation...
September 15, 2017: Sensors
https://www.readbyqxmd.com/read/28914621/ce-original-research-exploring-how-nursing-schools-handle-student-errors-and-near-misses
#13
Joanne Disch, Jane Barnsteiner, Susan Connor, Fabiana Brogren
This study, part 1 of a two-part series, reports survey findings that indicate areas for improvement. ABSTRACT: Background: Little attention has been paid to how nursing students learn about quality and safety, and to the tools and policies that guide nursing schools in helping students respond to errors and near misses. PURPOSE: This study sought to determine whether prelicensure nursing programs have a policy for reporting and following up on student clinical errors and near misses, a tool for such reporting, a tool or process (or both) for identifying trends, strategies for follow-up with students after errors and near misses, and strategies for follow-up with clinical agencies and individual faculty members...
September 13, 2017: American Journal of Nursing
https://www.readbyqxmd.com/read/28914122/improving-health-in-prisons-from-evidence-to-policy-to-implementation-experiences-from-the-uk
#14
Jane Leaman, Anna Amelia Richards, Lynn Emslie, Eamonn Joseph O'Moore
Purpose The purpose of this paper is to understand the components of a high-quality prison healthcare system and the impact, ten-years on, of the transfer of accountability in England, from a justice ministry to a health ministry. Design/methodology/approach A rapid the evidence review was undertaken, which included a review of 82 papers and qualitative interviews with key informants. The concepts and themes identified were summarised and analysed through a framework analysis, designed to improve population outcomes and address health inequalities...
September 11, 2017: International Journal of Prisoner Health
https://www.readbyqxmd.com/read/28913951/rapid-response-team-patients-triaged-to-remain-on-ward-despite-deranged-vital-signs-missed-opportunities
#15
J Tirkkonen, T Kontula, S Hoppu
BACKGROUND: Rapid response teams (RRTs) triage most patients to stay on ward, even though some of them have deranged vital signs according to RRTs themselves. We investigated the prevalence and outcome of this RRT patient cohort. METHODS: A prospective observational study was conducted in a Finnish tertiary referral centre, Tampere University Hospital. Data on RRT activations were collected between 1 May 2012 and 30 April 2015. Vital signs of patients triaged to stay on ward without treatment limitations were classified according to objective RRT trigger criteria observed during the reviews...
September 15, 2017: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/28913899/genotyping-by-sequencing-through-transcriptomics-implementation-in-a-range-of-crop-species-with-varying-reproductive-habits-and-ploidy-levels
#16
Michelle M Malmberg, Luke W Pembleton, Rebecca C Baillie, Michelle C Drayton, Shimna Sudheesh, Sukhjiwan Kaur, Hiroshi Shinozuka, Preeti Verma, German C Spangenberg, Hans D Daetwyler, John W Forster, Noel O I Cogan
The application of genomics in crops has the ability to significantly improve genetic gain for agriculture. Many marker-dense tools have been developed but few have seen broad adoption in plant genomics due to issues of significant variations of genome size, levels of ploidy, single nucleotide polymorphism (SNP) frequency and reproductive habit. When combined with limited breeding activities, small research communities and scant sequence resources, the suitability of popular systems is often sub-optimal and routinely fails to effectively balance cost-effectiveness and sample throughput...
September 15, 2017: Plant Biotechnology Journal
https://www.readbyqxmd.com/read/28913876/an-assessment-of-participant-described-interprofessional-oral-health-referral-systems-across-rurality
#17
Sean G Boynes, Abigail Lauer, Mark Deutchman, Amy B Martin
PURPOSE: As a means to identify and quantify oral health interprofessional collaborative practice (IPP), we examined participant-described medical-to-dental (M2D) referral networks and how they function across rurality. METHODS: We conducted a cross-sectional survey on the appraisal of IPP referral systems in 2016. Secondarily, we examined if rural health clinics (RHCs) have different experiences with M2D referrals compared to other practice types. Independent variables included geographic and organizational indicators, referral system attributes, and respondent characteristics...
September 15, 2017: Journal of Rural Health
https://www.readbyqxmd.com/read/28912480/genome-wide-rad-sequencing-data-provide-unprecedented-resolution-of-the-phylogeny-of-temperate-bamboos-poaceae-bambusoideae
#18
Xueqin Wang, Xiaying Ye, Lei Zhao, Dezhu Li, Zhenhua Guo, Huifu Zhuang
The temperate bamboos (tribe Arundinarieae, Poaceae) are strongly supported as monophyly in recent molecular studies, but taxonomic delineation and phylogenetic relationships within the tribe lack resolution. Here, we sampled 39 species (36 temperate bamboos and 3 outgroups) for restriction-site associated DNA sequencing (RAD-seq) with an emphasis on Phyllostachys clade and related clades. Using the largest data matrix for the bamboos to date, we were able to infer phylogenetic relationships with unparalleled resolution...
September 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28912350/reply-to-nash-color-terms-are-lost-despite-missing-data
#19
Claire Bowern, Hannah J Haynie
No abstract text is available yet for this article.
September 14, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28912195/associations-between-participation-in-organised-physical-activity-in-the-school-or-community-outside-school-hours-and-neighbourhood-play-with-child-physical-activity-and-sedentary-time-a-cross-sectional-analysis-of-primary-school-aged-children-from-the-uk
#20
Russell Jago, Corrie Macdonald-Wallis, Emma Solomon-Moore, Janice L Thompson, Debbie A Lawlor, Simon J Sebire
OBJECTIVES: To assess the extent to which participation in organised physical activity in the school or community outside school hours and neighbourhood play was associated with children's physical activity and sedentary time. DESIGN: Cross-sectional study. SETTING: Children were recruited from 47 state-funded primary schools in South West England. PARTICIPANTS: 1223 children aged 8-9 years old. OUTCOME MEASURES: Accelerometer-assessed moderate-to-vigorous-intensity physical activity (MVPA) and sedentary time...
September 14, 2017: BMJ Open
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