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https://www.readbyqxmd.com/read/28812230/simulation-of-left-ventricular-dynamics-using-a-low-order-mathematical-model
#1
Michael J Moulton, Brian D Hong, Timothy W Secomb
The eventual goal of this study is to develop methods for estimating dynamic stresses in the left ventricle (LV) that could be used on-line in clinical settings, based on routinely available measurements. Toward this goal, a low-order theoretical model is presented, in which LV shape is represented using a small number of parameters, allowing rapid computational simulations of LV dynamics. The LV is represented as a thick-walled prolate spheroid containing helical muscle fibers with nonlinear passive and time-dependent active contractile properties...
August 15, 2017: Cardiovascular Engineering and Technology
https://www.readbyqxmd.com/read/28811785/estimation-of-body-fat-in-pakistani-adult-a-comparison-of-equations-based-upon-skinfold-thickness-measurements
#2
Hafeeza Naz, Kinza Mushtaq, Bilal Azeem Butt, Khadija Irfan Khawaja
OBJECTIVE: To compare three different body fats estimation equations using skin fold measurements with bioelectrical impedance analysis. METHODS: A total of 130 subjects were included from Department of Endocrinology and Metabolism, Services Hospital, Lahore from 1(st) April 2016 to 30(th) Sep. 2016. The triceps, biceps, subscapular, chest, thigh, abdominal, suprailiac skinfold thickness of the subjects was measured with skin-fold calipers (Harpenden) on non-dominant side...
May 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28810943/language-barrier-as-a-risk-factor-for-injuries-from-patient-violence-among-direct-care-workers-in-home-settings-findings-from-a-u-s-national-sample
#3
Ha Do Byon, Shijun Zhu, George Unick, Carla Storr, Jane Lipscomb
This study explored potential risk factors for injuries from patient violence among direct care workers in U.S. homes (DCWHs). A national probability sample of 3,377 DCWHs including home health and personal care aides was analyzed using complex sample analysis and generalized estimating equation. Injury from violence was defined as a workrelated injury sustained by aggression, violence, or abuse that was reported to the agency, required medical attention or resulted in absenteeism from work. An association between suffering an injury from patient violence and having a language barrier with patients was noted (OR = 4...
August 15, 2017: Violence and Victims
https://www.readbyqxmd.com/read/28810783/self-consistent-calculation-of-protein-folding-pathways
#4
S Orioli, S A Beccara, P Faccioli
We introduce an iterative algorithm to efficiently simulate protein folding and other conformational transitions, using state-of-the-art all-atom force fields. Starting from the Langevin equation, we obtain a self-consistent stochastic equation of motion, which directly yields the reaction pathways. From the solution of this set of equations we derive a stochastic estimate of the reaction coordinate. We validate this approach against the results of plain MD simulations of the folding of a small protein, which were performed on the Anton supercomputer...
August 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28810127/medicaid-prior-authorization-and-opioid-medication-abuse-and-overdose
#5
Gerald Cochran, Adam J Gordon, Walid F Gellad, Chung-Chou H Chang, Wei-Hsuan Lo-Ciganic, Carroline Lobo, Evan Cole, Winfred Frazier, Ping Zheng, David Kelley, Julie M Donohue
OBJECTIVES: The US opioid medication epidemic has resulted in serious health consequences for patients. Formulary management tools adopted by payers, specifically prior authorization (PA) policies, may lower the rates of opioid medication abuse and overdose. We compared rates of opioid abuse and overdose among enrollees in plans that varied in their use of PA from "High PA" (ie, required PA for 17 to 74 opioids), with "Low PA" (ie, required PA for 1 opioid), and "No PA" policies for opioid medications...
May 1, 2017: American Journal of Managed Care
https://www.readbyqxmd.com/read/28809923/generalized-structural-equations-improve-sexual-selection-analyses
#6
Sonia Lombardi, Giacomo Santini, Giovanni Maria Marchetti, Stefano Focardi
Sexual selection is an intense evolutionary force, which operates through competition for the access to breeding resources. There are many cases where male copulatory success is highly asymmetric, and few males are able to sire most females. Two main hypotheses were proposed to explain this asymmetry: "female choice" and "male dominance". The literature reports contrasting results. This variability may reflect actual differences among studied populations, but it may also be generated by methodological differences and statistical shortcomings in data analysis...
2017: PloS One
https://www.readbyqxmd.com/read/28809793/the-degree-of-temporal-synchronization-of-the-pulse-oscillations-from-a-gain-switched-multimode-semiconductor-laser
#7
Kenji Wada, Naoaki Kitagawa, Tetsuya Matsuyama
Langevin noise leads to inhibition of the temporal synchronization of the pulse oscillations from a gain-switched multimode semiconductor laser, resulting in the power reduction in optical beat detection. In this paper, the degree of the temporal synchronization of the pulse oscillations was examined by numerically estimating the output energy in THz time-domain spectroscopy (THz-TDS) using multimode semiconductor laser rate equations that include Langevin noise. The degree was estimated to be 95.5% from the ratio of the averaged THz-TDS output energy for the case where Langevin noise was included to that for when Langevin noise was excluded...
August 15, 2017: Materials
https://www.readbyqxmd.com/read/28809681/a-prototype-therapy-system-for-transcutaneous-application-of-boiling-histotripsy
#8
Adam D Maxwell, Petr V Yuldashev, Wayne Kreider, Tatiana D Khokhlova, George R Schade, Timothy L Hall, Oleg A Sapozhnikov, Michael R Bailey, Vera A Khokhlova
Boiling histotripsy is a method of focused ultrasound surgery that noninvasively applies millisecond-length pulses with high-amplitude shock fronts to generate liquefied lesions in tissue. Such a technique requires unique outputs compared to a focused ultrasound thermal therapy apparatus, particularly to achieve high in situ pressure levels through intervening tissue. This article describes the design and characterization of a system capable of producing the necessary pressure to transcutaneously administer boiling histotripsy therapy through clinically relevant overlying tissue paths using pulses with duration up to 10 ms...
August 14, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28809035/nurse-staffing-patterns-and-patient-experience-of-care-an-empirical-analysis-of-u-s-hospitals
#9
Eva-Maria Oppel, Gary J Young
OBJECTIVE: To examine the relationship between nurse staffing patterns and patients' experience of care in hospitals with a particular focus on staffing flexibility. DATA SOURCES/STUDY SETTING: The study sample comprised U.S. general hospitals between 2010 and 2012. Nurse staffing data came from the American Hospital Association Annual Survey, and patient experience data came from the Medicare Hospital Consumer Assessment of Healthcare Providers and Systems. STUDY DESIGN: An observational research design was used entailing a pooled, cross-sectional data set...
August 14, 2017: Health Services Research
https://www.readbyqxmd.com/read/28806430/a-randomized-controlled-trial-of-mastication-with-complete-dentures-made-by-a-conventional-or-an-abbreviated-technique
#10
Cristiane Machado Mengatto, Gustavo Hauber Gameiro, Mario Brondani, C Peter Owen, Michael I MacEntee
PURPOSE: The aim of this randomized clinical trial was to test the hypothesis that there are no statistically significant differences after 3 and 6 months in masticatory performance or chewing ability of people with new complete dentures made by an abbreviated or a conventional technique. MATERIALS AND METHODS: The trial included 20 edentulous participants at a dental school in Brazil assigned randomly to receive dentures made by either a conventional technique involving six clinical sessions or by an abbreviated technique involving three clinical sessions...
August 14, 2017: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/28806425/impact-of-different-surgeons-on-dental-implant-failure
#11
Bruno Ramos Chrcanovic, Jenö Kisch, Tomas Albrektsson, Ann Wennerberg
PURPOSE: To assess the influence of several factors on the prevalence of dental implant failure, with special consideration of the placement of implants by different dental surgeons. MATERIALS AND METHODS: This retrospective study is based on 2,670 patients who received 10,096 implants at one specialist clinic. Only the data of patients and implants treated by surgeons who had inserted a minimum of 200 implants at the clinic were included. Kaplan-Meier curves were stratified with respect to the individual surgeon...
August 14, 2017: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/28805929/the-impact-of-training-strategies-on-the-accuracy-of-genomic-predictors-in-united-states-red-angus-cattle
#12
J Lee, S D Kachman, M L Spangler
Genomic selection (GS) has become an integral part of genetic evaluation methodology and has been applied to all major livestock species, including beef and dairy cattle, pigs, and chickens. Significant contributions in increased accuracy of selection decisions have been clearly illustrated in dairy cattle after practical application of GS. In the majority of U.S. beef cattle breeds, similar efforts have also been made to increase the accuracy of genetic merit estimates through the inclusion of genomic information into routine genetic evaluations using a variety of methods...
August 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28805912/prediction-of-fecal-nitrogen-and-phosphorus-excretion-for-chinese-holstein-lactating-dairy-cows
#13
Q B Qu, P Yang, R Zhao, S L Zhi, Z W Zhai, F F Ding, K Q Zhang
Mathematical models for predicting nitrogen and phosphorus excretion play a key role in manure application and environment monitoring. An analysis for prediction of fecal nitrogen (FN, g/d) and fecal phosphorus (FP, g/d) excretion for Chinese Holstein lactating dairy cows was conducted using a data set from 15 dairy farms in northern China. The whole independent-variable data set, obtained with questionnaires, consisted of 110 sets of average diet nutrient compositions, including DMI (kg/d), CP content (% DM), OM intake (OMI, kg/d), nitrogen intake (NI, g/d), and phosphorus intake (PI, g/d), and animal characteristics, including average days in milk (DIM, d), average milk yield (MY, kg/d), and average BW (kg)...
August 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28805429/the-effect-of-scopolamine-on-matching-behavior-and-the-estimation-of-relative-reward-magnitude
#14
Matthew I Leon, Vanessa Rodriguez-Barrera, Aldo Amaya
We investigated the behavioral effects of scopolamine on rats that bar pressed for trains of electrically stimulating pulses under concurrent variable interval schedules of reward. For the first half of the session (30 min) a 1:4 ratio in the programmed number of stimulation trains delivered at each option was in effect. At the start of the second half of the session, an unsignaled reversal in the relative train number (4:1) occurred. We tracked the relative magnitude of reward estimated for each contiguous pair of reinforced visits to competing options...
August 14, 2017: Behavioral Neuroscience
https://www.readbyqxmd.com/read/28805191/presenting-a-new-kinetic-model-for-methanol-to-light-olefins-reactions-over-a-hierarchical-sapo-34-catalyst-using-the-langmuir-hinshelwood-hougen-watson-mechanism
#15
Mohammad Javad Azarhoosh, Rouein Halladj, Sima Askari
In this study, a new kinetic model for methanol to light olefins (MTO) reactions over a hierarchical SAPO-34 catalyst using the Langmuir-Hinshelwood-Hougen-Watson mechanism was presented and the kinetic parameters was obtained using genetic algorithm (GA) and genetic programming (GP). Several kinetic models for the MTO reactions, have been presented. However, due to the complexity of the reactions, most reactions are considered lumped and elementary, which cannot be deemed a completely accurate kinetic model of the process...
August 14, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28804697/evaluation-of-satellite-and-reanalysis-based-global-net-surface-energy-flux-and-uncertainty-estimates
#16
Chunlei Liu, Richard P Allan, Michael Mayer, Patrick Hyder, Norman G Loeb, Chris D Roberts, Maria Valdivieso, John M Edwards, Pier-Luigi Vidale
The net surface energy flux is central to the climate system yet observational limitations lead to substantial uncertainty. A combination of satellite-derived radiative fluxes at the top of atmosphere adjusted using the latest estimation of the net heat uptake of the Earth system, and the atmospheric energy tendencies and transports from the ERA-Interim reanalysis are used to estimate surface energy flux globally. To consider snowmelt and improve regional realism, land surface fluxes are adjusted through a simple energy balance approach at each grid point...
June 27, 2017: Journal of Geophysical Research. Atmospheres: JGR
https://www.readbyqxmd.com/read/28804470/evaluating-fit-indices-for-multivariate-t-based-structural-equation-modeling-with-data-contamination
#17
Mark H C Lai, Jiaqi Zhang
In conventional structural equation modeling (SEM), with the presence of even a tiny amount of data contamination due to outliers or influential observations, normal-theory maximum likelihood (ML-Normal) is not efficient and can be severely biased. The multivariate-t-based SEM, which recently got implemented in Mplus as an approach for mixture modeling, represents a robust estimation alternative to downweigh the impact of outliers and influential observations. To our knowledge, the use of maximum likelihood estimation with a multivariate-t model (ML-t) to handle outliers has not been shown in SEM literature...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28804240/dual-method-use-among-postpartum-hiv-infected-and-hiv-uninfected-malawian-women-a-prospective-cohort-study
#18
Dawn M Kopp, Jennifer H Tang, Gretchen S Stuart, William C Miller, Michele S O'Shea, Mina C Hosseinipour, Phylos Bonongwe, Mwawi Mwale, Nora E Rosenberg
Dual method use, use of condoms plus another effective contraceptive method, is important in settings with high rates of unintended pregnancy and HIV infection. We evaluated the association of HIV status with dual method use in a cohort of postpartum women. Women completed baseline surveys in the postpartum ward and telephone surveys about contraceptive use 3, 6, and 12 months later. Nonpregnant women who completed at least one follow-up survey were eligible for this secondary analysis. Prevalence ratios were calculated using generalized estimating equations...
2017: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28803856/bioenergetic-costs-and-state-influence-distance-perception
#19
David Francis Hunt, Heidi B N Hunt, Justin H Park
Bioenergetic resources and states have been found to influence visual perception, with greater expected energy expenditure being associated with perceptions of greater distances and steeper slopes. Here we tested whether resting metabolic rate (RMR), which can serve as a proxy for the bioenergetic costs of completing physical activity, is positively correlated with perceived distance. We also tested whether temporarily depleting bioenergetic resources through exercise would result in greater perceived distance...
August 10, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28803840/development-and-validation-of-risk-equations-for-complications-of-type-2-diabetes-recode-using-individual-participant-data-from-randomised-trials
#20
Sanjay Basu, Jeremy B Sussman, Seth A Berkowitz, Rodney A Hayward, John S Yudkin
BACKGROUND: In view of substantial mis-estimation of risks of diabetes complications using existing equations, we sought to develop updated Risk Equations for Complications Of type 2 Diabetes (RECODe). METHODS: To develop and validate these risk equations, we used data from the Action to Control Cardiovascular Risk in Diabetes study (ACCORD, n=9635; 2001-09) and validated the equations for microvascular events using data from the Diabetes Prevention Program Outcomes Study (DPPOS, n=1018; 1996-2001), and for cardiovascular events using data from the Action for Health in Diabetes (Look AHEAD, n=4760; 2001-12)...
August 10, 2017: Lancet Diabetes & Endocrinology
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