keyword
https://read.qxmd.com/read/38491690/influence-of-donor-or-acceptor-presence-on-excitation-states-in-molecular-chains-nonadiabatic-polaron-approach
#21
JOURNAL ARTICLE
V Matic, Z Ivic, Z Przulj, D Chevizovich
In this paper, we considered a molecular structure that consists of a molecular chain and an additional molecule (donor or acceptor) that can inject (or remove) single excitation (vibron, electron, etc.) onto the molecular chain. We assumed that the excitation forms a self-trapped state due to the interaction with mechanical oscillations of the chain structure elements. We analyzed the energy spectra of the excitation and showed that its state (when it migrates to the molecular chain) has the properties of the nonadiabatic polaron state...
February 2024: Physical Review. E
https://read.qxmd.com/read/38491531/pregnancy-and-obstetric-outcomes-of-dichorionic-triamniotic-triplet-pregnancies-with-selective-foetal-reduction-after-assisted-reproductive-technology
#22
JOURNAL ARTICLE
Shuhua Liu, Qianhua Xu, Dehong Liu, Qiuru Li, Jingyu Qian, Bin Zhang, Xianxia Chen
BACKGROUND: It is generally beneficial and recommended that dichorionic triamniotic (DCTA) triplet pregnancies be reduced to monochorionic (MC) twin or singleton pregnancies after assisted reproductive technology (ART). However, some infertile couples still have a firm desire to retain twins. For this reason, the best foetal reduction strategies need to be available for infertile couples and clinicians. Given that data on the elective reduction of DCTA triplet pregnancies to twin pregnancies are scarce, we investigated the outcomes of elective reduction of DCTA triplet pregnancies through the retrospective analysis of previous data...
March 15, 2024: Reproductive Biology and Endocrinology: RB&E
https://read.qxmd.com/read/38491521/quality-of-life-among-residents-of-gaza-palestine-the-predictive-role-of-mental-distress-fear-of-covid-19-and-social-support
#23
JOURNAL ARTICLE
Suhayla Said Jalala, Guido Veronese, Marwan Diab, Yasser Abu Jamei, Rawya Hamam, Ashraf Kagee
BACKGROUND: Living under siege and deteriorated health, social, educational, and economic conditions and isolation with scarce opportunities to fulfil basic needs and aspirations affect the civil population's mental health and perceived quality of life. In this cross-sectional investigation, we explored the consequences of mental distress, fear of COVID-19, and social support for QoL in the Gaza strip. METHODS: Nine hundred seventy nine (32.9% males; 67.1% females; mean age was 35...
March 15, 2024: BMC Psychology
https://read.qxmd.com/read/38491435/beyond-a-spec-assessing-heterogeneity-in-the-unregulated-opioid-supply
#24
JOURNAL ARTICLE
Lea Gozdzialski, Rebecca Louw, Collin Kielty, Ava Margolese, Eric Poarch, Miriam Sherman, Fred Cameron, Chris Gill, Bruce Wallace, Dennis Hore
BACKGROUND: Drug checking services aim to provide compositional information for the illicit drug supply and are being employed in public health responses to extreme rates of overdose associated with fentanyl within street opioids. The technologies used within these services range from basic qualitative tests, such as immunoassay test strips, to comprehensive quantitative analyses, such as mass spectrometry. In general, there is concern that heterogeneity of a drug mixture adds significant uncertainty when using drug checking results based on a small subsamples...
March 15, 2024: Harm Reduction Journal
https://read.qxmd.com/read/38491427/using-team-based-precision-medicine-to-advance-understanding-of-rare-genetic-brain-disorders
#25
REVIEW
Steven U Walkley, Sophie Molholm, Bryen Jordan, Robert W Marion, Melissa Wasserstein
We describe a multidisciplinary teamwork approach known as "Operation IDD Gene Team" developed by the Rose F. Kennedy Intellectual and Developmental Disabilities Research Center (RFK IDDRC) at the Albert Einstein College of Medicine. This initiative brings families affected by rare genetic diseases that cause intellectual and developmental disability together with physicians, basic scientists, and their trainees. At team meetings, family members share their child's medical and personal history, physicians describe the broader clinical consequences of the condition, and scientists provide accessible tutorials focused on the fundamental biology of relevant genes...
March 15, 2024: Journal of Neurodevelopmental Disorders
https://read.qxmd.com/read/38491291/characterizing-the-immune-response-to-myocardial-infarction-in-pigs
#26
JOURNAL ARTICLE
Florian Schnitter, Franziska Stangl, Elisabeth Noeske, Maya Bille, Anja Stadtmüller, Niklas Vogt, Florian Sicklinger, Florian Leuschner, Anna Frey, Laura Schreiber, Stefan Frantz, Niklas Beyersdorf, Gustavo Ramos, Nadine Gladow, Ulrich Hofmann
Though myocardial infarction (MI) in pigs is a well-established translational large animal model, it has not yet been widely used for immunotherapy studies, and a comprehensive description of the immune response to MI in this species is lacking. We induced MI in Landrace pigs by balloon occlusion of the left anterior descending artery over 90 min. Within 14 days, the necrotic myocardium was progressively replaced by scar tissue with involvement of myofibroblasts. We characterized the immune response in the heart ex vivo by (immuno)histology, flow cytometry, and RNA sequencing of myocardial tissue on days 3, 7, and 14 after MI...
March 15, 2024: Basic Research in Cardiology
https://read.qxmd.com/read/38491242/integrated-biomarker-responses-in-wild-populations-of-the-intertidal-sea-anemone-bunodosoma-zamponii-living-under-different-anthropogenic-pressures
#27
JOURNAL ARTICLE
Nicolas D Vazquez, Andrea C Crupkin, Melisa A Chierichetti, Fabián H Acuña, Karina S B Miglioranza
Bunodosoma zamponii is the most abundant anemone in Mar del Plata (Buenos Aires, Argentina). Given that the presence of persistent organic pollutants (organochlorine pesticides and PCBs) and the organophosphate pesticide chlorpyrifos has recently been reported in this species, two wild populations living under different anthropogenic pressures were studied and compared regarding basic aspects of their ecology and physiological response to oxidative stress. A population from an impacted site (Las Delicias, LD) and another from a reference site (Punta Cantera, PC) were monitored seasonally (spring, summer, autumn, and winter), for one year...
March 16, 2024: Environmental Science and Pollution Research International
https://read.qxmd.com/read/38491224/-r-0-may-not-tell-us-everything-transient-disease-dynamics-of-some-sir-models-over-patchy-environments
#28
JOURNAL ARTICLE
Ao Li, Xingfu Zou
This paper examines the short-term or transient dynamics of SIR infectious disease models in patch environments. We employ reactivity of an equilibrium and amplification rates, concepts from ecology, to analyze how dispersals/travels between patches, spatial heterogeneity, and other disease-related parameters impact short-term dynamics. Our findings reveal that in certain scenarios, due to the impact of spatial heterogeneity and the dispersals, the short-term disease dynamics over a patch environment may disagree with the long-term disease dynamics that is typically reflected by the basic reproduction number...
March 15, 2024: Bulletin of Mathematical Biology
https://read.qxmd.com/read/38491217/viral-infection-dynamics-with-immune-chemokines-and-ctl-mobility-modulated-by-the-infected-cell-density
#29
JOURNAL ARTICLE
Hongying Shu, Hai-Yang Jin, Xiang-Sheng Wang, Jianhong Wu
We study a viral infection model incorporating both cell-to-cell infection and immune chemokines. Based on experimental results in the literature, we make a standing assumption that the cytotoxic T lymphocytes (CTL) will move toward the location with more infected cells, while the diffusion rate of CTL is a decreasing function of the density of infected cells. We first establish the global existence and ultimate boundedness of the solution via a priori energy estimates. We then define the basic reproduction number of viral infection <mml:math xmlns:mml="https://www...
March 15, 2024: Journal of Mathematical Biology
https://read.qxmd.com/read/38491105/dynamic-constitutive-identification-of-concrete-based-on-improved-dung-beetle-algorithm-to-optimize-long-short-term-memory-model
#30
JOURNAL ARTICLE
Ping Li, Haonan Zhao, Jiming Gu, Shiwei Duan
In order to improve the accuracy of concrete dynamic principal identification, a concrete dynamic principal identification model based on Improved Dung Beetle Algorithm (IDBO) optimized Long Short-Term Memory (LSTM) network is proposed. Firstly, the apparent stress-strain curves of concrete containing damage evolution were measured by Split Hopkinson Pressure Bar (SHPB) test to decouple and separate the damage and rheology, and this system was modeled by using LSTM network. Secondly, for the problem of low convergence accuracy and easy to fall into local optimum of Dung Beetle Algorithm (DBO), the greedy lens imaging reverse learning initialization population strategy, the embedded curve adaptive weighting factor and the PID control optimal solution perturbation strategy are introduced, and the superiority of IDBO algorithm is proved through the comparison of optimization test with DBO, Harris Hawk Optimization Algorithm, Gray Wolf Algorithm, and Fruit Fly Algorithm and the combination of LSTM is built to construct the IDBO-LSTM dynamic homeostasis identification model...
March 15, 2024: Scientific Reports
https://read.qxmd.com/read/38491094/the-neuroanatomy-of-developmental-language-disorder-a-systematic-review-and-meta-analysis
#31
JOURNAL ARTICLE
Michael T Ullman, Gillian M Clark, Mariel Y Pullman, Jarrett T Lovelett, Elizabeth I Pierpont, Xiong Jiang, Peter E Turkeltaub
Developmental language disorder (DLD) is a common neurodevelopmental disorder with adverse impacts that continue into adulthood. However, its neural bases remain unclear. Here we address this gap by systematically identifying and quantitatively synthesizing neuroanatomical studies of DLD using co-localization likelihood estimation, a recently developed neuroanatomical meta-analytic technique. Analyses of structural brain data (22 peer-reviewed papers, 577 participants) revealed highly consistent anomalies only in the basal ganglia (100% of participant groups in which this structure was examined, weighted by group sample sizes; 99...
March 15, 2024: Nature Human Behaviour
https://read.qxmd.com/read/38491031/transcriptomic-profiling-of-poa-pratensis-l-under-treatment-of-various-phytohormones
#32
JOURNAL ARTICLE
Chen Meng, Xiaomei Peng, Yu Zhang, García-Caparrós Pedro, Yumeng Li, Yanni Zhang, Yuanwen Duan, Xudong Sun
Poa pratensis L. (Poaceae) is a valuable grass across the north hemisphere, inhabiting diverse environments with wide altitudinal span, where ubiquitous various kinds of stresses. Phytohormones would be helpful to improve tolerance to abiotic and biotic stresses, but the responses of transcriptome regulation of P. pratensis to exogenous phytohormones application remain unclear. In this study, we explored the alteration of plant physiological responses by the application of phytohormones. Aiming to achieve this knowledge, we got full-length transcriptome data 42...
March 15, 2024: Scientific Data
https://read.qxmd.com/read/38490997/rhesus-infant-nervous-temperament-predicts-peri-adolescent-central-amygdala-metabolism-behavioral-inhibition-measured-by-a-machine-learning-approach
#33
JOURNAL ARTICLE
D Holley, L J Campos, C M Drzewiecki, Y Zhang, J P Capitanio, A S Fox
Anxiety disorders affect millions of people worldwide and impair health, happiness, and productivity on a massive scale. Developmental research points to a connection between early-life behavioral inhibition and the eventual development of these disorders. Our group has previously shown that measures of behavioral inhibition in young rhesus monkeys (Macaca mulatta) predict anxiety-like behavior later in life. In recent years, clinical and basic researchers have implicated the central extended amygdala (EAc)-a neuroanatomical concept that includes the central nucleus of the amygdala (Ce) and the bed nucleus of the stria terminalis (BST)-as a key neural substrate for the expression of anxious and inhibited behavior...
March 15, 2024: Translational Psychiatry
https://read.qxmd.com/read/38490974/impact-of-weekday-on-short-term-surgical-outcomes-after-lumbar-fusion-surgery
#34
JOURNAL ARTICLE
Jeremy C Heard, Teeto Ezeonu, Yunsoo Lee, Rajkishen Narayanan, Tariq Issa, Cordero McCall, Yoni Dulitzki, Dylan Resnick, Jeffrey Zucker, Alexander Shaer, Mark Kurd, Alan S Hilibrand, Alexander R Vaccaro, Christopher K Kepler, Gregory D Schroeder, Jose A Canseco
STUDY DESIGN: Retrospective cohort study. OBJECTIVE: The purpose of this study is to investigate whether weekday lumbar spine fusion surgery has an impact on surgical and inpatient physical therapy (PT) outcomes. SUMMARY OF BACKGROUND DATA: Timing of surgery has been implicated as a factor that may impact outcomes after spine surgery. Previous literature suggests that there may be an adverse effect to having surgery on the weekend. METHODS: All patients ≥18 years who underwent primary lumbar spinal fusion from 2014 to 2020 were retrospectively identified...
March 12, 2024: Clinical Spine Surgery
https://read.qxmd.com/read/38490848/nationwide-study-on-open-tibial-fractures-in-the-netherlands-incidence-demographics-and-level-of-hospital-care
#35
JOURNAL ARTICLE
M P Noorlander-Borgdorff, A Şekercan, D A Young-Afat, M Bouman, M Botman, G F Giannakópoulos
OBJECTIVES: Open tibial fractures are relatively common injuries following traffic accidents. The vulnerability of the soft tissues surrounding the tibia increases the susceptibility to complications, including infection and nonunion. To minimize complications, a multidisciplinary, timely approach is crucial. To date, the Dutch incidence and level of hospital treatment remain unknown due to a lack of condition-specific nationwide registries. This study aimed to estimate the incidence and management of open tibial fractures in the Netherlands, providing essential information for public health policymaking and guideline development...
March 3, 2024: Injury
https://read.qxmd.com/read/38490779/inhaled-nitroglycerin-for-pulmonary-edema-in-air-medical-services-a-retrospective-pilot-study
#36
JOURNAL ARTICLE
Abigail Polzin, Eric D Curtis, Eric Rupe, Hilla I Sang
OBJECTIVE: The use of traditional inhaled pulmonary vasodilators, such as nitric oxide, to treat symptomatic pulmonary edema is not practical in the air medical or prehospital environment because of difficulty with administration. A hospital-based critical care air medical transport service initiated a pilot study to investigate the use of inhaled nitroglycerin (iNTG) as an alternative pulmonary vasodilator. METHODS: For this pilot study, iNTG was administered using a jet nebulizer setup and concentrated nitroglycerin, both of which are widely available in acute care settings...
2024: Air Medical Journal
https://read.qxmd.com/read/38490773/association-of-geographic-distance-and-hospital-characteristics-with-use-of-interhospital-transfer-by-air-a-multicenter-retrospective-study
#37
JOURNAL ARTICLE
Bennett H Lane, David J Rea, Adam L Gottula, Andrew D Cathers, Ryan M Ziegler, Andrew J Latimer, Kyle R Danielson, B Jason Theiling, Craig M Froehle, William R Hinckley
OBJECTIVE: Interhospital transfer by air (IHTA) represents the majority of helicopter air ambulance transports in the United States, but the evaluation of what factors are associated with utilization has been limited. We aimed to assess the association of geographic distance and hospital characteristics (including patient volume) with the use of IHTA. METHODS: This was a multicenter, retrospective study of helicopter flight request data from 2018 provided by a convenience sample of 4 critical care transport medicine programs in 3 US census regions...
2024: Air Medical Journal
https://read.qxmd.com/read/38490743/alpha-and-beta-oscillations-differentially-support-word-production-in-a-rule-switching-task
#38
JOURNAL ARTICLE
Ioanna Zioga, Ying Joey Zhou, Hugo Weissbart, Andrea E Martin, Saskia Haegens
Research into the role of brain oscillations in basic perceptual and cognitive functions has suggested the alpha rhythm reflects functional inhibition while the beta rhythm reflects neural ensemble (re)activation. However, little is known regarding the generalization of these proposed fundamental operations to linguistic processes, such as speech comprehension and production. Here, we recorded magnetoencephalography (MEG) in participants performing a novel rule-switching paradigm. Specifically, Dutch native speakers had to produce an alternative exemplar from the same category or a feature of a given target word embedded in spoken sentences (e...
March 15, 2024: ENeuro
https://read.qxmd.com/read/38490735/clinical-implementation-of-automated-o-2-titration-in-a-tertiary-care-hospital
#39
JOURNAL ARTICLE
Pierre-Alexandre Bouchard, Geneviève Parent-Racine, Cassiopée Paradis-Gagnon, Mathieu Simon, Yves Lacasse, François Lellouche, François Maltais
Background: When treating acute respiratory failure, both hypoxemia and hyperoxemia should be avoided. SpO2 should be monitored closely and O2 flows adjusted accordingly. Achieving this goal might be easier with automated O2 titration compared to manual titration of fixed-flow O2 We evaluated the feasibility of using an automated O2 titration device in subjects treated for acute hypoxemic respiratory failure in a tertiary care hospital. Methods: Healthcare workers received education and training about oxygen therapy and were familiarized with an automated O2 titration device (FreeO2, Oxynov, Quebec City, Canada)...
March 15, 2024: Respiratory Care
https://read.qxmd.com/read/38490365/congenital-anosmia-and-facial-emotion-recognition
#40
JOURNAL ARTICLE
James Drummond, Adarsh Makdani, Ralph Pawling, Susannah C Walker
Major functions of the olfactory system include guiding ingestion and avoidance of environmental hazards. People with anosmia report reliance on others, for example to check the edibility of food, as their primary coping strategy. Facial expressions are a major source of non-verbal social information that can be used to guide approach and avoidance behaviour. Thus, it is of interest to explore whether a life-long absence of the sense of smell heightens sensitivity to others' facial emotions, particularly those depicting threat...
March 13, 2024: Physiology & Behavior
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