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https://www.readbyqxmd.com/read/29149796/effectiveness-of-treatment-in-wards-for-patients-with-dementia-and-issues-associated-with-this-treatment-a-prospective-analysis
#1
Shogo Taniguchi, Teruyuki Matsuoka, Takeshi Hikawa, Atsushi Machihara, Keisuke Shibata, Hideki Miki, Hiroshi Shimizu, Jin Narumoto
In order to optimize the treatment in wards for patients with dementia, we investigated predictors of the length of stay in the ward for patients with dementia. A prospective analysis of 72 patients with dementia was conducted in two wards for patients with dementia. Severity of dementia was assessed by the Clinical Dementia Rating, basic activities of daily living were evaluated using the Physical Self-Maintenance Scale, and severity of behavioral and psychological symptoms of dementia and caregiver distress were determined with the Nursing Home version of the Neuropsychiatric Inventory...
January 1, 2017: Dementia
https://www.readbyqxmd.com/read/29149775/lentiviral-vectors-and-adeno-associated-virus-vectors-useful-tools-for-gene-transfer-in-pain-research
#2
REVIEW
Zheng Chen-Xi, Wang Sheng-Ming, Bai Yun-Hu, Luo Ting-Ting, Wang Jia-Qi, Dai Chun-Qiu, Guo Bao-Lin, Luo Shi-Cheng, Wang Dong-Hui, Yang Yan-Ling, Wang Ya-Yun
Pain, especially chronic pain, has always been a heated point in both basic and clinical researches since it puts heavy burdens on both individuals and the whole society. A better understanding of the role of biological molecules and various ionic channels involved in pain can shed light on the mechanism under pain and advocate the development of pain management. Using viral vectors to transfer specific genes at targeted sites is a promising method for both research and clinical applications. Lentiviral vectors and adeno-associated virus (AAV) vectors which allow stable and long-term expression of transgene in non-dividing cells are widely applied in pain research...
November 17, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29149538/psychologic-intimate-partner-violence-and-the-risk-of-intrauterine-growth-restriction-in-rio-de-janeiro
#3
Gustavo Lobato, Michael E Reichenheim, Claudia L Moraes, Fernando M Peixoto-Filho, Lívia S Migowski
OBJECTIVE: To evaluate whether psychologic intimate partner violence (IPV) during pregnancy is a risk factor for intrauterine growth restriction (IUGR). METHODS: The cross-sectional study enrolled 810 randomly selected mothers of infants younger than 5 months attending basic health services in Rio de Janeiro, Brazil, from January to July 2007. Psychologic and physical IPV were evaluated by the Revised Conflict Tactics Scale; IUGR was defined as below the 10th percentile of the Alexander curve...
November 17, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29149501/the-weakly-coordinating-tris-trichlorosilyl-silyl-anion
#4
Marian Olaru, Maxie F Hesse, Elena Rychagova, Sergey Ketkov, Stefan Mebs, Jens Beckmann
Closely following the procedure for the preparation of the base-stabilized dichlorosilylene complex NHCDipp∙SiCl2 by Roesky and Stalke et al. (Angew. Chem. Int. Ed. 2009, 48, 5683-5686), besides the reported by-product [NHCDipp-H+∙∙∙Cl-], few crystals of the salt [NHCDipp-H∙∙∙Cl∙∙∙H-NHCDipp]Si(SiCl3)3 were isolated and characterized by X-ray crystallography (NHCDipp = N,N-di(2,6-isopropylphenyl)-imidazo-2-ylidene). They feature the weakly-coordinating anion Si(SiCl3)3-, which was more rationally obtained in high yields upon deprotonation of conjugate Brønsted acid HSi(SiCl3)3 with NHCDipp or PMP (PMP = 1,2,2,6,6-pentamethylpiperidine)...
November 17, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/29149486/discovery-of-vg-and-vgr-gene-expression-profiles-related-to-host-plant-suitability-of-spodoptera-exigua
#5
Jing Zhao, Yang Sun, Liubin Xiao, Yongan Tan, Yiping Jiang, Lixin Bai
BACKGROUND: Spodoptera exigua, a worldwide phytophagous pest, causes considerable economic agricultural losses. Understanding the relationship between its fecundity and host plant is a basic and important component of early forecasting of beet armyworm. However, little is known about the molecular mechanism by which distinct hosts affect S. exigua fecundity. RESULTS: In this study, the key parameters of S. exigua grown on distinct hosts were investigated; host plants could be ranked as lettuce >shallot > tomato > celery in their order of suitability...
November 17, 2017: Pest Management Science
https://www.readbyqxmd.com/read/29149485/factors-influencing-the-delivery-of-the-fundamentals-of-care-perceptions-of-nurses-nursing-leaders-and-healthcare-consumers
#6
Tiffany Conroy
AIM AND OBJECTIVES: To explore the factors described by nurses and consumer representatives influencing the delivery of the fundamentals of care. BACKGROUND: An ongoing challenge facing nursing is ensuring the 'basics' or fundamentals of care are delivered optimally. The way nurses and patients perceive the delivery of the fundamentals of care, had not been explored. Once identified, the factors that promote the delivery of the fundamentals of care may be facilitated ...
November 17, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29149471/polyaniline-derived-n-doped-carbon-coated-cobalt-phosphide-nanoparticles-deposited-on-n-doped-graphene-as-an-efficient-electrocatalyst-for-hydrogen-evolution-reaction
#7
Jingwen Ma, Min Wang, Guangyu Lei, Guoliang Zhang, Fengbao Zhang, Wenchao Peng, Xiaobin Fan, Yang Li
The development of highly efficient and durable non-noble metal electrocatalysts for the hydrogen evolution reaction (HER) is significant for clean and renewable energy research. This work reports the synthesis of N-doped graphene nanosheets supported N-doped carbon coated cobalt phosphide (CoP) nanoparticles via a pyrolysis and a subsequent phosphating process by using polyaniline. The obtained electrocatalyst exhibits excellent electrochemical activity for HER with a small overpotential of -135 mV at 10 mA cm(-2) and a low Tafel slope of 59...
November 17, 2017: Small
https://www.readbyqxmd.com/read/29149422/interrelationships-among-hydrogen-permeation-physiochemical-properties-and-early-adsorption-abilities-of-titanium
#8
Fang Jia, Lei Zhou, Wangxi Wu
This study aimed to investigate if the titanium samples with low hydrogen permeation which treated with a novel etching combination: phosphoric acid and sodium fluoride could influence the surface physiochemical properties and early adsorption ability. Titanium samples were treated with three different concentrations of the new formula, as groups A, B and C, and treated with the traditional etching formula, as group T. Zeta potential, contact angle, X-ray photoelectron spectroscopy (XPS) and fibronectin (FN)/vitronectin (VN) adsorption of Sprague-Dawley (SD) rat tibial osteotomies in the initial 30min and MG-63 adsorption in the initial 24 h were detected...
November 17, 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/29149377/multi-patch-and-multi-group-epidemic-models-a-new-framework
#9
Derdei Bichara, Abderrahman Iggidr
We develop a multi-patch and multi-group model that captures the dynamics of an infectious disease when the host is structured into an arbitrary number of groups and interacts into an arbitrary number of patches where the infection takes place. In this framework, we model host mobility that depends on its epidemiological status, by a Lagrangian approach. This framework is applied to a general SEIRS model and the basic reproduction number [Formula: see text] is derived. The effects of heterogeneity in groups, patches and mobility patterns on [Formula: see text] and disease prevalence are explored...
November 17, 2017: Journal of Mathematical Biology
https://www.readbyqxmd.com/read/29149359/-preclinical-and-intrahospital-management-of-mass-casualties-and-terrorist-incidents
#10
REVIEW
A Franke, D Bieler, B Friemert, E Kollig, S Flohe
Due to the recent terrorist attacks in Paris, Brussels, Ansbach, Munich, Berlin and more recently Manchester and London, terrorism is realized as a present threat to our society and social life, as well as a challenge for the health care system. Without fueling anxiety, there is a need for sensitization to this subject and to familiarize all concerned with the special kind of terrorist attack-related injuries, the operational priorities and tactics and the individual basic principles of preclinical and hospital care...
October 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/29149335/liberty-in-health-care-a-comparative-study-between-hong-kong-and-mainland-china
#11
Jingxian Wu, Ying Mao
This essay contends that individual liberty, understood as the permissibility of making choices about one's own health care in support of one's own good and the good of one's family utilizing private resources, is central to the moral foundations of a health care system. Such individual freedoms are important not only because they often support more efficient and effective health care services, but because they permit individuals to fulfill important moral duties. A comparative study of the health care systems in Hong Kong and mainland China is utilized to illustrate the conceptual and moral concerns at stake...
November 15, 2017: Journal of Medicine and Philosophy
https://www.readbyqxmd.com/read/29149325/the-iuphar-bps-guide-to-pharmacology-in-2018-updates-and-expansion-to-encompass-the-new-guide-to-immunopharmacology
#12
Simon D Harding, Joanna L Sharman, Elena Faccenda, Chris Southan, Adam J Pawson, Sam Ireland, Alasdair J G Gray, Liam Bruce, Stephen P H Alexander, Stephen Anderton, Clare Bryant, Anthony P Davenport, Christian Doerig, Doriano Fabbro, Francesca Levi-Schaffer, Michael Spedding, Jamie A Davies
The IUPHAR/BPS Guide to PHARMACOLOGY (GtoPdb, www.guidetopharmacology.org) and its precursor IUPHAR-DB, have captured expert-curated interactions between targets and ligands from selected papers in pharmacology and drug discovery since 2003. This resource continues to be developed in conjunction with the International Union of Basic and Clinical Pharmacology (IUPHAR) and the British Pharmacological Society (BPS). As previously described, our unique model of content selection and quality control is based on 96 target-class subcommittees comprising 512 scientists collaborating with in-house curators...
November 15, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29149264/sim3c-simulation-of-hi-c-and-meta3c-proximity-ligation-sequencing-technologies
#13
Matthew Z DeMaere, Aaron E Darling
Background: Chromosome conformation capture (3C) and Hi-C DNA sequencing methods have rapidly advanced our understanding of the spatial organization of genomes and metagenomes. Many variants of these protocols have been developed, each with their own strengths. Currently there is no systematic means for simulating sequence data from this family of sequencing protocols, potentially hindering the advancement of algorithms to exploit this new datatype. Findings: We describe a computational simulator that, given simple parameters and reference genome sequences, will simulate Hi-C sequencing on those sequences...
November 15, 2017: GigaScience
https://www.readbyqxmd.com/read/29149235/isolated-complexes-of-the-amino-acid-arginine-with-polyether-and-polyamine-macrocycles-the-role-of-proton-transfer
#14
Juan Ramón Avilés-Moreno, Giel Berden, Jos Oomens, Bruno Martínez-Haya
The distinct basicity of the guanidinium side-group of arginine (Arg) sustains specific interactions involved in essential biochemical processes. The sensing of arginine is therefore key in modern biotechnology and bioanalysis. In this context, the development of molecular receptors based on crown ether building blocks has demonstrated great potential. We investigate the complexes formed by arginine with two benchmark macrocycles, 12-crown-4 (1,4,7,10-tetraoxacyclododecane) and its N-substituted analog cyclen (1,4,7,10-tetraazacyclododecane)...
November 17, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29149127/percutaneous-nephrostomy-infusion-nursing-considerations-for-treatment-of-upper-urinary-tract-urothelial-carcinoma
#15
Eryn Draganski, Ellen Sterman, Kathy Morris
An intrarenal approach using a percutaneous nephrostomy tube is a novel method to deliver chemotherapy and biotherapy to patients with upper urinary tract urothelial carcinoma. A paucity of evidence exists regarding basic nursing implications for this unique treatment option. This column will provide suggested guidelines to administer intrarenal treatment via a percutanous nephrostomy tube.
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December 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/29149120/genomics-education-knowledge-of-nurses-across-the-profession-and-integration-into-practice
#16
Lisa B Aiello
BACKGROUND: Since the completion of the Human Genome Project in 2003, the implications of genetics and genomics for health and illness have become clearer. All nurses, at all levels and across all specialties, must have a basic understanding of genetics and genomics to provide appropriate care. 
. OBJECTIVES: This article provides an overview of the integration of genetics and genomics into nursing education, as well as continued barriers to nursing knowledge of genetics and genomics...
December 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/29149064/who-participates-in-the-great-shakeout-why-audience-segmentation-is-the-future-of-disaster-preparedness-campaigns
#17
Rachel M Adams, Beth Karlin, David P Eisenman, Johanna Blakley, Deborah Glik
Background: In 2008, the Southern California Earthquake Center in collaboration with the U.S. Geological Survey Earthquake Hazards Program launched the first annual Great ShakeOut, the largest earthquake preparedness drill in the history of the United States. Materials and Methods: We collected online survey data from 2052 campaign registrants to assess how people participated, whether audience segments shared behavioral patterns, and whether these segments were associated with five social cognitive factors targeted by the ShakeOut campaign...
November 17, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29149024/the-role-of-the-mammalian-prion-protein-in-the-control-of-sleep
#18
REVIEW
Amber Roguski, Andrew C Gill
Sleep disruption is a prevalent clinical feature in many neurodegenerative disorders, including human prion diseases where it can be the defining dysfunction, as in the case of the "eponymous" fatal familial insomnia, or an early-stage symptom as in certain types of Creutzfeldt-Jakob disease. It is important to establish the role of the cellular prion protein (PrP(C)), the key molecule involved in prion pathogenesis, within the sleep-wake system in order to understand fully the mechanisms underlying its contribution to both healthy circadian rhythmicity and sleep dysfunction during disease...
November 17, 2017: Pathogens
https://www.readbyqxmd.com/read/29148788/temperature-dependent-empirical-parameters-for-polarity-in-choline-chloride-based-deep-eutectic-solvents
#19
Arun Valvi, Jyoti Dutta, Shraeddha Tiwari
Deep eutectic solvents have emerged as a promising and economically viable alternative to address our need for environmentally benign media. Efficient utilization of deep eutectic solvents in various fields will require adequate knowledge about their physicochemical properties. In this work, independent polarity scales pertaining to solvent polarizability, dipolarity, acidity and basicity have been determined for some commonly used deep eutectic solvents based on choline chloride. The three eutectic mixtures selected for the study include reline (1:2 mixture of choline chloride and urea), ethaline (1:2 mixture of choline chloride and ethylene glycol) and glyceline (1:2 mixture of choline chloride and glycerol)...
November 17, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/29148396/multiple-reassorted-viruses-as-cause-of-highly-pathogenic-avian-influenza-a-h5n8-virus-epidemic-the-netherlands-2016
#20
Nancy Beerens, Rene Heutink, Saskia A Bergervoet, Frank Harders, Alex Bossers, Guus Koch
In 2016, an epidemic of highly pathogenic avian influenza A virus subtype H5N8 in the Netherlands caused mass deaths among wild birds, and several commercial poultry farms and captive bird holdings were affected. We performed complete genome sequencing to study the relationship between the wild bird and poultry viruses. Phylogenetic analysis showed that the viruses are related to H5 clade 2.3.4.4 viruses detected in Russia in May 2016 but contained novel polymerase basic 2 and nucleoprotein gene segments and 2 different variants of the polymerase acidic segment...
December 2017: Emerging Infectious Diseases
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