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https://www.readbyqxmd.com/read/29786973/amniotic-fluid-lactic-acid-and-matrix-metalloproteinase-8-levels-at-the-time-of-fetal-surgery-for-a-spine-defect-association-with-subsequent-premature-preterm-rupture-of-membranes
#1
Antonio F Moron, Aikaterini Athanasiou, Mauricio Barbosa, Herbene J Milani, Stephanno G Sarmento, Sergio Cavalheiro, Steven S Witkin
OBJECTIVE: In utero fetal surgery to correct incomplete closure of the spinal cord lessens the extent of permanent damage but is associated with preterm premature rupture of membranes (pPROM). We determined if compounds in amniotic fluid (AF) collected at the time of surgery predicted subsequent development of pPROM. DESIGN: Prospective study. SETTING: Hospitals in Sao Paulo, Brazil. POPULATION: Twenty four consecutive pregnant women at 24-26 weeks gestation seen between February and October 2017 with a singleton pregnancy underwent in utero surgery to correct an open spinal defect in their fetus...
May 22, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29786871/gender-specific-effects-of-selection-for-drinking-in-the-dark-on-the-network-roles-of-coding-and-non-coding-rnas
#2
Ovidiu Dan Iancu, Alex Colville, Beth Wilmot, Robert Searles, Priscila Darakjian, Christina Zheng, Shannon McWeeney, Sunita Kawane, John C Crabbe, Pamela Metten, Denesa Oberbeck, Robert Hitzemann
BACKGROUND: Transcriptional differences between Heterogeneous stock (HS/NPT) mice and High Drinking in the Dark (HDID) selected mouse lines have previously been described based on microarray technology coupled with network based analysis (Iancu et al., 2013b). The network changes were reproducible in two independent selections and largely confined to two distinct network modules; in contrast differential expression appeared more specific to each selected line. The current study extends these results by utilizing RNA-Seq technology, allowing evaluation of the relationship between genetic risk and transcription of non-coding RNA; we additionally evaluate sex-specific transcriptional effects of selection...
May 22, 2018: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29786654/a-comparative-study-of-oral-health-status-between-international-and-japanese-university-student-patients-in-japan
#3
Ai Ohsato, Masanobu Abe, Kazumi Ohkubo, Hidemi Yoshimasu, Liang Zong, Kazuto Hoshi, Tsuyoshi Takato, Shintaro Yanagimoto, Kazuhiko Yamamoto
Background: The number of international students enrolled in universities in Japan is increasing. To provide better oral care services for international students, we have to understand their oral environment and dental health behaviors. However, few studies have investigated the oral health status of international university students. The object of the present study was to clarify the current oral status of international university students. Methods: The subjects were students who visited the dental department at the University of Tokyo's Health Services Center between April 2012 and March 2013...
May 22, 2018: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/29786461/gender-and-diagnostic-impact-on-everyday-technology-use-a-differential-item-functioning-dif-analysis-of-the-everyday-technology-use-questionnaire-etuq
#4
Anders Kottorp, Camilla Malinowsky, Maria Larsson-Lund, Louise Nygård
BACKGROUND: As the use of everyday technology is increasingly important for participation in daily activities, more in-depth knowledge of everyday technology use in relation to diagnosis and gender is needed. The purpose of this study was to investigate the stability of the perceived challenge of a variety of everyday technologies across different samples of varying diagnoses including both males and females. METHODS: This cross-sectional study used 643 data records from clinical and research samples, including persons with dementia or related disorders, acquired brain injury, intellectual disability, various mental or medical disorders, and adults without known diagnoses...
May 22, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29786140/gender-differences-in-the-association-of-periodontitis-and-type-2-diabetes
#5
Ying Liu, Yang Yu, Jeffrey C Nickel, Laura R Iwasaki, Peipei Duan, Melanie Simmer-Beck, Laura Brown
AIMS: THE OBJECTIVE WAS TO INVESTIGATE IF GENDER DIFFERENCES EXIST IN THE ASSOCIATIONS BETWEEN PERIODONTITIS AND TYPE 2 DIABETES. DISPROPORTIONATE DISPARITIES BY GENDER WERE FOUND TO EXIST IN RATES OF BOTH PERIODONTITIS AND DIABETES WITH RESPECT TO DEMOGRAPHICS AND BEHAVIOURAL PREDICTORS THAT CANNOT BE EXPLAINED SOLELY BY THE WELL-ESTABLISHED ASSOCIATION BETWEEN THESE TWO DISEASES. MATERIALS AND METHODS: MULTIPLE DATASETS WERE EXTRACTED FROM THE NATIONAL HEALTH AND NUTRITION EXAMINATION SURVEY (NHANES) 2009-2014, WHICH USED A STRATIFIED MULTISTAGE PROBABILITY SAMPLING TO OBTAIN SAMPLES FROM ALL CIVILIAN NON-INSTITUTIONALISED PEOPLE IN THE USA...
May 22, 2018: International Dental Journal
https://www.readbyqxmd.com/read/29786041/fixation-versus-excision-of-osteochondral-fractures-after-patellar-dislocations-in-adolescent-patients-a-retrospective-cohort-study
#6
Hui Kang, Jian Li, Xu-Xu Chen, Tao Wang, Shi-Chang Liu, Hong-Chuan Li
Background: Patellar dislocation is one of the most common knee injuries in the adolescent population. It is often combined with osteochondral fracture. The purpose of this study was to compare the outcomes between fixation and excision of osteochondral fractures not involving the bearing surface in adolescent patients with patellar dislocations. Methods: Patients who underwent surgery for osteochondral fracture following patellar dislocation in our institution from 2007 to 2014 were retrospectively evaluated...
June 5, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29785965/inflammatory-bowel-disease-increases-the-risk-of-parkinson-s-disease-a-danish-nationwide-cohort-study-1977-2014
#7
Marie Villumsen, Susana Aznar, Bente Pakkenberg, Tine Jess, Tomasz Brudek
OBJECTIVE: Intestinal inflammation has been suggested to play a role in development of Parkinson's disease (PD) and multiple system atrophy (MSA). To test the hypothesis that IBD is associated with risk of PD and MSA, we performed a nationwide population-based cohort study. DESIGN: The cohort consisted of all individuals diagnosed with IBD in Denmark during 1977-2014 (n=76 477) and non-IBD individuals from the general population, who were comparable in terms of gender, age and vital status (n=7 548 259)...
May 21, 2018: Gut
https://www.readbyqxmd.com/read/29785935/the-impact-of-dysphonic-voices-on-children-s-comprehension-of-spoken-language
#8
Johnny C-H Chui, Estella P-M Ma
BACKGROUND: This study investigated the effect of teachers' dysphonic voices on children's listening comprehension. METHODS: One hundred thirty-four grade three and four students were recruited from local primary schools in Hong Kong. They were required to listen to six passages, three in Cantonese and three in English, which were either read in normal, mildly dysphonic, or severely dysphonic voices. The students were required to complete six multiple-choice comprehension questions upon listening to each passage...
May 18, 2018: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29785696/case-matched-comparison-of-long-term-functional-and-quality-of-life-outcomes-following-laparoscopic-versus-open-ileal-pouch-anal-anastomosis
#9
Olga A Lavryk, Luca Stocchi, Jean H Ashburn, Meagan Costedio, Emre Gorgun, Tracy L Hull, Hermann Kessler, Conor P Delaney
BACKGROUND: Laparoscopic ileal pouch-anal anastomosis (IPAA) is associated with recovery benefits when compared with open IPAA. There is limited data on long-term quality of life and functional outcomes, which this study aimed to assess. METHODS: An IRB-approved, prospectively maintained database was queried to identify patients undergoing laparoscopic IPAA (L), case-matched with open IPAA (O) based on age ± 5 years, gender, body mass index (BMI) ± 5 kg/m2 , diagnosis, date of surgery ± 3 years, stapled/handsewn anastomosis, omission of diverting loop ileostomy and length of follow-up ± 3 years...
May 21, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29785679/drooling-in-parkinson-s-disease-evidence-of-a-role-for-divided-attention
#10
Hannah Reynolds, Nick Miller, Richard Walker
Drooling is a frequently reported symptom in Parkinson's Disease (PD) with significant psychosocial impact and negative health consequences including silent aspiration of saliva with the associated risk of respiratory infections. It is suggested that in PD drooling is associated with inefficient oropharyngeal swallowing which reduces the effective clearance of saliva rather than hyper-salivation. This is compounded by unintended mouth opening and flexed posture increasing anterior loss of saliva. It is reported to occur most frequently during cognitively distracting concurrent tasks suggesting an impact from divided attention in a dual-task situation...
May 21, 2018: Dysphagia
https://www.readbyqxmd.com/read/29785581/anti-jc-virus-antibody-sera-positivity-and-index-value-among-patients-with-multiple-sclerosis-may-be-correlated-with-age-sex-and-area-of-residence
#11
Sogol Koolaji, Narges Sistany Allahabadi, Arash Ahmadi, Sharareh Eskandarieh, Abdorreza Naser Moghadasi, Amir Reza Azimi, Mohammad Ali Sahraian
Anti-JC virus (JCV) antibody index is the predictive factor of progressive multifocal leukoencephalopathy (PML) for multiple sclerosis (MS) patients treating with natalizumab. The aim of this study is to evaluate the prevalence of anti-JCV antibody positivity and index among Iranian patients who are the candidate for natalizumab and its correlation with their demographic data and previous therapies. A cross-sectional design was assessed for receiving anti-JCV antibody test results between January 2014 and December 2016...
May 21, 2018: Journal of Neurovirology
https://www.readbyqxmd.com/read/29785580/a-comprehensive-review-and-meta-analysis-of-risk-factors-for-statin-induced-myopathy
#12
REVIEW
Khoa A Nguyen, Lang Li, Deshun Lu, Aida Yazdanparast, Lei Wang, Rolf P Kreutz, Elizabeth C Whipple, Titus K Schleyer
PURPOSE: To aid prescribers in assessing a patient's risk for statin-induced myopathy (SIM), we performed a comprehensive review of currently known risk factors and calculated aggregated odds ratios for each risk factor through a meta-analysis. METHODS: This meta-analysis was done through four phases: (1) Identification of the relevant primary literature; (2) abstract screening using inclusion and exclusion criteria; (3) detailed review and data extraction; and (4) synthesis and statistical analysis...
May 22, 2018: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29785272/abdominal-obesity-in-type-1-diabetes-associated-with-gender-cardiovascular-risk-factors-and-complications-and-difficulties-achieving-treatment-targets-a-cross-sectional-study-at-a-secondary-care-diabetes-clinic
#13
Eva O Melin, Hans O Thulesius, Magnus Hillman, Mona Landin-Olsson, Maria Thunander
Background: Abdominal obesity is linked to cardiovascular diseases in type 1 diabetes (T1D). The primary aim was to explore associations between abdominal obesity and cardiovascular complications, metabolic and inflammatory factors. The secondary aim was to explore whether achieved recommended treatment targets differed between the obese and non-obese participants. Methods: Cross sectional study of 284 T1D patients (age 18-59 years, men 56%), consecutively recruited from one secondary care specialist diabetes clinic in Sweden...
2018: BMC Obesity
https://www.readbyqxmd.com/read/29785200/comparative-study-on-knowledge-about-autism-spectrum-disorder-among-paediatric-and-psychiatric-nurses-in-public-hospitals-in-kumasi-ghana
#14
Wireko-Gyebi Sampson, Ashiagbor Emelia Sandra
Background: Despite the existence of autism spectrum disorder in Ghana, few studies have provided the necessary information on the phenomenon. These studies have mostly focused on speech and language therapy for children and modification of classroom environment for children with autism spectrum disorder. This approach has resulted in a paucity of knowledge on nurse's knowledge of autism spectrum disorder in Ghana. Objective: The study sought to assess the knowledge of paediatric and psychiatric on autism spectrum disorder...
2018: Clinical Practice and Epidemiology in Mental Health: CP & EMH
https://www.readbyqxmd.com/read/29785097/inter-gender-differences-of-balance-indicators-in-persons-60-90-years-of-age
#15
Ewa Puszczalowska-Lizis, Przemyslaw Bujas, Slawomir Jandzis, Jaroslaw Omorczyk, Marek Zak
Introduction: Precision of movements responsible for maintaining balance deteriorates with age due to natural involutionary processes, thus prompting a research question whether the values of gender-related stability indicators might differ significantly among the study subjects over 60 years of age. Methods: The study group comprised 136 seniors (89 women, 47 men; aged 60-90 years). The CQ-Stab 2P 2-platform posturograph was used as the main research device, whereas the Mann-Whitney U -test was used to evaluate the gender-related differences in the average level of variables...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29784970/association-of-blood-pressure-with-fasting-blood-glucose-levels-in-northeast-china-a-cross-sectional-study
#16
Yaogai Lv, Yan Yao, Junsen Ye, Xin Guo, Jing Dou, Li Shen, Anning Zhang, Zhiqiang Xue, Yaqin Yu, Lina Jin
Hypertension and diabetes mellitus (DM) have become major public health issues, and previous studies have shown that there is an association between hypertension and DM. However, there is a lack of detailed information about this association. This study aimed to explore how different blood pressure (BP) levels were associated with fasting blood glucose (FBG) levels. A cross-sectional survey with adults aged 18 to 79 years was conducted in Jilin Province, China in 2012. Lambda-mu-sigma (LMS) was used to preliminarily explore the associations of BP with FBG...
May 21, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29784116/gendered-mechanisms-underlie-the-relation-between-pubertal-timing-and-adult-depressive-symptoms
#17
Adriene M Beltz
PURPOSE: Sex differences in depression emerge in adolescence, in concert with puberty. Off-time maturers, especially early-maturing girls, report more depressive symptoms than their same-sex peers. Recent evidence shows that these pubertal timing effects persist into adulthood, but the underlying mechanisms are unclear. METHODS: Participants were 318 young adults (201 women, 117 men) who rated their depressive symptoms in the past 2 weeks and provided valid retrospective reports of their pubertal timing...
June 2018: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/29784112/technology-based-interventions-to-reduce-sexually-transmitted-infections-and-unintended-pregnancy-among-youth
#18
REVIEW
Laura Widman, Jacqueline Nesi, Kristyn Kamke, Sophia Choukas-Bradley, J L Stewart
PURPOSE: Technology-based interventions to promote sexual health have proliferated in recent years, yet their efficacy among youth has not been meta-analyzed. This study synthesizes the literature on technology-based sexual health interventions among youth. METHODS: Studies were included if they (1) sampled youth ages 13-24; (2) utilized technology-based platforms; (3) measured condom use or abstinence as outcomes; (4) evaluated program effects with experimental or quasi-experimental designs; and (5) were published in English...
June 2018: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/29784045/occupational-risk-factors-for-idiopathic-pulmonary-fibrosis-in-southern-europe-a-case-control-study
#19
Giulia Paolocci, Ilenia Folletti, Kjell Torén, Magnus Ekström, Marco Dell'Omo, Giacomo Muzi, Nicola Murgia
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive fibrosing interstitial pneumonia of unknown cause associated with the histopathologic and/or radiologic pattern of usual interstitial pneumonia (UIP). Occupational risk factors have been proposed to be associated with UIP. The aim of this case-control study is to evaluate the relationship between UIP pattern and occupational exposure in Southern Europe. METHODS: Sixty nine cases with a UIP radiological pattern at CT-scan were selected from a clinical database of the University Hospital of Perugia, Umbria, between January 2010 and December 2013...
May 21, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29783764/intensity-of-multilingual-language-use-predicts-cognitive-performance-in-some-multilingual-older-adults
#20
Anna Pot, Merel Keijzer, Kees de Bot
Cognitive advantages for bilinguals have inconsistently been observed in different populations, with different operationalisations of bilingualism, cognitive performance, and the process by which language control transfers to cognitive control. This calls for studies investigating which aspects of multilingualism drive a cognitive advantage, in which populations and under which conditions. This study reports on two cognitive tasks coupled with an extensive background questionnaire on health, wellbeing, personality, language knowledge and language use, administered to 387 older adults in the northern Netherlands, a small but highly multilingual area...
May 19, 2018: Brain Sciences
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