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focal liver lesions

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https://www.readbyqxmd.com/read/29133753/transcatheter-arterial-chemoembolization-combined-with-simultaneous-computed-tomography-guided-radiofrequency-ablation-for-large-hepatocellular-carcinomas
#1
Tai-Yang Zuo, Feng-Yong Liu, Mao-Qiang Wang, Xian-Xian Chen
BACKGROUND: Currently, the treatment of large hepatocellular carcinoma (HCC) is still a challenging problem. Transcatheter arterial chemoembolization (TACE) is the main treatment for intermediate end-stage HCC, while it is only a palliative and not a curative treatment due to the existence of residual tumors, and radiofrequency ablation (RFA) has limitations in complete ablation of large HCC. We hypothesized that TACE combined with simultaneous RFA (herein referred to as TACE + RFA) could improve the efficacy and survival of large HCC...
November 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/29133247/contrast-enhanced-ultrasound-identifies-hepatocellular-carcinoma-in-cirrhosis-a-large-multicenter-retrospective-study
#2
Eleonora Terzi, Massimo Iavarone, Maurizio Pompili, Letizia Veronese, Giuseppe Cabibbo, Mirella Fraquelli, Laura Riccardi, Ludovico De Bonis, Angelo Sangiovanni, Simona Leoni, Maria Assunta Zocco, Sandro Rossi, Nicola Alessi, Stephanie R Wilson, Fabio Piscaglia, Alessandro Granito, Veronica Salvatore, Francesco Tovoli, Matteo Angelo Manini, Gian Lodovico Rapaccini, Maria Elena Ainora, Valentina Ravetta, Giorgia Ghittoni, Agostino Ventra, Giuseppe Mogavero
BACKGROUND & AIMS: The use of contrast enhanced ultrasound (CEUS) for the diagnosis of hepatocellular carcinoma (HCC) in cirrhosis was questioned for the risk of false positive diagnosis in case of cholangiocarcinoma. The American College of Radiology has recently released a scheme (CEUS LI-RADS) classifying lesions at risk for HCC investigated by CEUS. Aim of the present study was to validate this LI-RADS scheme for the diagnosis of HCC. METHODS: A total of 1006 nodules in 848 patients with chronic liver disease at risk for HCC collected in 5 Italian centers were retrospectively analyzed...
November 10, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/29120569/abdominal-ultrasound-%C3%A2-the-leading-method-in-duodenal-gist-diagnostics
#3
Sven Bohnec, Ivan Budimir, Davor Hrabar, Nenad Babić, Ivan Budimir, Marko Nikolić, Ivana Pavić
Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the digestive tract and are generally asymptomatic. A 39-year-old female patient was hospitalized in 2012 at Clinical Department of Internal Medicine, Sestre milosrdnice University Hospital Center, for a focal hypodense irregular circular lesion located in segment III of the left hepatic lobe, accidentally found by ultrasonography and verified by computed tomography. The findings were also verified with nuclear magnetic resonance and esophagogastroduodenoscopy...
March 2017: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29110059/differentiating-focal-nodular-hyperplasia-from-hepatocellular-adenoma-is-hepatobiliary-phase-mri-hbp-mri-using-linear-gadolinium-chelates-always-useful
#4
Marion Roux, Frederic Pigneur, Laurence Baranes, Julien Calderaro, Mélanie Chiaradia, Thomas Decaens, Sandrine Kastahian, Anaïs Charles-Nelson, Lambros Tselikas, Charlotte Costentin, Alexis Laurent, Daniel Azoulay, Ariane Mallat, Alain Rahmouni, Alain Luciani
PURPOSE: To assess the value of Hepatobiliary phase MRI (HPB-MRI) to differentiate FNH and HCA, and evaluate its impact on diagnostic accuracy, diagnostic confidence, inter-observer variability, and patient clinical management. METHODS: Forty-nine patients referred for Gd-BOPTA-enhanced MRI were retrospectively included in this IRB-approved study, with a total of 119 lesions-90 FNH and 29 HCA. Two observers separately assessed in 2 distinct randomized reading sessions the performance of MRI with (HBP-MRI) or without (conventional MRI) the use of HBP images...
November 6, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29108077/characterization-of-focal-liver-lesions-using-ceus-and-mri-with-liver-specific-contrast-media-experience-of-a-single-radiologic-center
#5
Lukas Philipp Beyer, Florian Wassermann, Benedikt Pregler, Katharina Michalik, Janine Rennert, Isabel Wiesinger, Christian Stroszczynski, Philipp Wiggermann, Ernst Michael Jung
Aim The purpose of this study was to compare contrast-enhanced ultrasound (CEUS), magnetic resonance imaging (MRI) using liver-specific contrast agent and a combination of both for the characterization of focal liver lesions (FLL). Methods 83 patients with both benign and malignant liver lesions were examined using CEUS and MRI after the intravenous administration of liver-specific contrast media. All patients had inconclusive results from prior imaging examinations. Histopathological specimens could be obtained in 53 patients...
November 6, 2017: Ultraschall in der Medizin
https://www.readbyqxmd.com/read/29105019/texture-specific-bag-of-visual-words-model-and-spatial-cone-matching-based-method-for-the-retrieval-of-focal-liver-lesions-using-multiphase-contrast-enhanced-ct-images
#6
Yingying Xu, Lanfen Lin, Hongjie Hu, Dan Wang, Wenchao Zhu, Jian Wang, Xian-Hua Han, Yen-Wei Chen
PURPOSE: The bag of visual words (BoVW) model is a powerful tool for feature representation that can integrate various handcrafted features like intensity, texture, and spatial information. In this paper, we propose a novel BoVW-based method that incorporates texture and spatial information for the content-based image retrieval to assist radiologists in clinical diagnosis. METHODS: This paper presents a texture-specific BoVW method to represent focal liver lesions (FLLs)...
November 5, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/29103478/liver-investigations-updating-on-us-technique-and-contrast-enhanced-ultrasound-ceus
#7
REVIEW
Valentina Battaglia, Rosa Cervelli
Over the past few years, the cross sectional imaging techniques (Computed Tomography - CT and Magnetic Resonance - MR) have improved, allowing a more efficient study of focal and diffuse liver diseases. Many papers had been published about the results of a routinely clinical use of the dual source/dual energy CT techniques and the use of hepatobiliary contrast agents in MR liver studies. As a consequence, these new improvements have diverted the attention away from the Ultrasound technique and its technical and conceptual evolutions...
November 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/29094174/contrast-enhanced-ultrasound-of-malignant-liver-lesions
#8
Isabelle Durot, Stephanie R Wilson, Jürgen K Willmann
Contrast-enhanced ultrasound (CEUS) is a safe, relatively inexpensive, and widely available imaging technique using dedicated imaging ultrasound sequences and FDA-approved contrast microbubbles that allow detection and characterization of malignant focal liver lesions with high diagnostic accuracy. CEUS provides dynamic real-time imaging with high spatial and temporal capability, allowing for unique contributions to the already established protocols for diagnosing focal liver lesions using CT and MR imaging...
November 1, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29072980/focal-liver-lesions-computer-aided-diagnosis-by-using-contrast-enhanced-us-cine-recordings
#9
Casey N Ta, Yuko Kono, Mohammad Eghtedari, Young Taik Oh, Michelle L Robbin, Richard G Barr, Andrew C Kummel, Robert F Mattrey
Purpose To assess the performance of computer-aided diagnosis (CAD) systems and to determine the dominant ultrasonographic (US) features when classifying benign versus malignant focal liver lesions (FLLs) by using contrast material-enhanced US cine clips. Materials and Methods One hundred six US data sets in all subjects enrolled by three centers from a multicenter trial that included 54 malignant, 51 benign, and one indeterminate FLL were retrospectively analyzed. The 105 benign or malignant lesions were confirmed at histologic examination, contrast-enhanced computed tomography (CT), dynamic contrast-enhanced magnetic resonance (MR) imaging, and/or 6 or more months of clinical follow-up...
October 25, 2017: Radiology
https://www.readbyqxmd.com/read/29068577/which-organ-should-be-considered-a-reference-in-diffusion-weighted-imaging-of-the-abdomen-the-reproducibility-of-adc-measurements-of-the-spleen-and-the-renal-cortex-on-a-1-5t-mr
#10
Aleksander Pawluś, Kinga Szymańska, Mateusz Łasecki, Joanna Bladowska, Dąbrówka Sokołowska-Dąbek, Małgorzata Szumarska-Czech, Krzysztof Kaczorowski, Bartosz D Markiewicz, Krzysztof Dudek, Urszula Zaleska-Dorobisz
BACKGROUND: Diffusion weighted imaging (DWI) is a useful tool for the evaluation of focal lesions in the liver or kidneys, as well as for the diagnosis and assessment of the liver fibrosis process. Some reports show that the spleen and kidneys may serve as reference organs in the staging of liver fibrosis or the evaluation of focal liver lesions. OBJECTIVES: The aim of the study was to determine whether the spleen and renal cortex can be used as reference organs in the DWI technique...
August 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29061130/-18-f-fdg-pet-ct-helps-differentiate-autoimmune-pancreatitis-from-pancreatic-cancer
#11
Jian Zhang, Guorong Jia, Changjing Zuo, Ningyang Jia, Hui Wang
BACKGROUND: (18)F-FDG PET/CT could satisfactorily show pancreatic and extra-pancreatic lesions in AIP, which can be mistaken for pancreatic cancer (PC). This study aimed to identify (18)F-FDG PET/CT findings that might differentiate AIP from PC. METHODS: FDG-PET/CT findings of 26 AIP and 40 PC patients were reviewed. Pancreatic and extra-pancreatic lesions related findings, including maximum standardized uptake values (SUVmax) and patterns of FDG uptake, were identified and compared...
October 23, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29055931/congenital-shunts-of-the-portal-venous-system-case-series-of-uncommon-shunts
#12
Liliana Santos, Susana Nobre, Nadia Laezza, Catarina Cunha, Isabel Gonçalves, Maria F Lopes
BACKGROUND AND AIMS: Congenital shunts of the portal venous system are rare entities that can present in children with clinical heterogeneity. To evaluate the clinical course of children with uncommon shunts presenting to our institution and examine the available literature on this topic. Medical records of children with rare forms of congenital shunts were retrospectively reviewed for demographics, symptoms, management, and outcome between 2003 and 2016. RESULTS: Three female patients with congenital shunts, including a congenital mesenterico-portal Rex shunt (n = 1) and congenital portosystemic shunts (CPSS) (n = 2), were referred for surgical evaluation between ages 4 and 9...
October 16, 2017: Annals of Hepatology
https://www.readbyqxmd.com/read/29054942/primary-hepatic-hemangioendothelioma-in-a-patient-with-budd-chiari-syndrome
#13
Preet Mukesh Shah, Vijay Waman Dhakre, Aabha Nagral
A 36-year-old woman was diagnosed with compensated cirrhosis of liver secondary to Budd-Chiari syndrome (BCS) and had undergone stenting of a thrombosed left hepatic vein. Eight months later, she presented with jaundice and right upper quadrant pain. CT revealed multiple focal lesions in the liver, which on biopsy proved to be hepatic hemangioendothelioma (HHE). Her liver disease and ascites progressively increased. Four months later, magnetic resonance cholangiopancreatography showed an advanced stage of HHE with infiltration of the common bile duct and vascular invasion with a blocked stent, with metastasis to the spleen and dorsolumbar vertebrae...
October 19, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29051991/radiation-induced-liver-injury-mimicking-liver-metastases-on-fdg-pet-ct-after-chemoradiotherapy-for-esophageal-cancer-a%C3%A2-retrospective-study-and-literature-review
#14
Francine E M Voncken, Berthe M P Aleman, Jolanda M van Dieren, Cecile Grootscholten, Ferry Lalezari, Johanna W van Sandick, Jeffrey D Steinberg, Erik Vegt
BACKGROUND: For esophageal cancer patients treated with neoadjuvant chemoradiotherapy (nCRT), restaging using F‑18-fluorodeoxyglucose (FDG) positron emission tomography computed tomography (PET-CT) following nCRT can detect interval metastases, including liver metastases, in almost 10% of patients. However, in clinical practice, focal FDG liver uptake, unrelated to liver metastases, is observed after chemoradiotherapy. This radiation-induced liver injury (RILI) can potentially lead to overstaging...
October 19, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/29029443/quantitative-evaluation-of-gd-eob-dtpa-uptake-in-focal-liver-lesions-by-using-t1-mapping-differences-between-hepatocellular-carcinoma-hepatic-focal-nodular-hyperplasia-and-cavernous-hemangioma
#15
Zhenpeng Peng, Chang Li, Tao Chan, Huasong Cai, Yanji Luo, Zhi Dong, Zi-Ping Li, Shi-Ting Feng
OBJECTIVES: To investigate the difference of T1 relaxation time on Gd-EOB-DTPA-enhanced MRI in hepatocellular carcinoma (HCC), hepatic focal nodular hyperplasia (FNH) and cavernous hemangioma of liver (CHL), and to quantitatively evaluate the uptake of Gd-EOB-DTPA in these three focal liver lesions (FLLs). RESULTS: The T1P of CHL was significantly higher than those of HCC and FNH (P < 0.05). Reduction of T1 relaxation time on hepatobiliary phase could be observed in all three types of lesions...
September 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/29028279/liver-elastography-malignancy-prediction-lemp-score-for-noninvasive-characterization-of-focal-liver-lesions
#16
Ivica Grgurevic, Tomislav Bokun, Nermin N Salkic, Boris Brkljacic, Mirjana Vukelić-Markovic, Tajana Stoos-Veic, Gorana Aralica, Mislav Rakic, Tajana Filipec-Kanizaj, Annalisa Berzigotti
BACKGROUND & AIMS: To analyse elastographic characteristics of focal liver lesions (FLL)s and diagnostic performance of real-time two-dimensional shear-wave elastography (RT-2D-SWE) in order to differentiate benign and malignant FLLs. PATIENTS AND METHODS: Consecutive patients diagnosed with FLL by abdominal ultrasound (US) underwent RT-2D-SWE of FLL and non-infiltrated liver by intercostal approach over the right liver lobe. The nature of FLL was determined by diagnostic work-up, including at least one contrast-enhanced imaging modality (MDCT/MRI), check-up of target organs when metastatic disease was suspected and FLL biopsy in inconclusive cases...
October 13, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/29023148/nonstandardized-terminology-to-describe-focal-liver-lesions-in-patients-at-risk-for-hepatocellular-carcinoma-implications-regarding-clinical-communication
#17
Michael T Corwin, Andrew Y Lee, Ghaneh Fananapazir, Thomas W Loehfelm, Souvik Sarkar, Claude B Sirlin
OBJECTIVE: The purpose of this study is to determine the correlation between malignancy risk of focal liver observations in patients at risk for hepatocellular carcinoma (HCC) implied by phrases used in nonstructured radiology reports with the risk inferred by hepatologists. MATERIALS AND METHODS: We performed a retrospective review of nonstructured radiology reports issued before Liver Imaging and Reporting Data System (LI-RADS) adoption from four-phase liver CT examinations of patients at risk for HCC...
October 12, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29019750/contrast-enhanced-us-assessment-of-focal-liver-lesions-in-children
#18
Sudha A Anupindi, David M Biko, Aikaterini Ntoulia, Laura Poznick, Trudy A Morgan, Kassa Darge, Susan J Back
Ultrasonography (US) is often the first line of imaging for the examination of children suspected of having liver lesions. However, gray-scale US with color Doppler imaging has limitations. The use of US contrast agents has recently been approved by the U.S. Food and Drug Administration (FDA). Compared with other imaging modalities, contrast material-enhanced US (CEUS) enables the assessment of contrast enhancement patterns with a higher temporal resolution and is therefore becoming a valuable alternative imaging technique...
October 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28990224/evaluation-of-haematological-serum-biochemical-and-histopathological-parameters-of-growing-rabbits-fed-amaranthus-dubius
#19
E Molina, P González-Redondo, R Moreno-Rojas, K Montero-Quintero, N Chirinos-Quintero, A Sánchez-Urdaneta
Amaranthus dubius is an alternative source of fibre and protein for the feed formulation for growing rabbits, although its effects on their health status are yet unknown. Therefore, this study aimed to evaluate the effects of three dietary levels (0, 160 and 320 g/kg) of A. dubius on haematological, serum biochemical and histopathological parameters of fattening rabbits. One hundred and thirteen New Zealand White rabbits were fed ad libitum from weaning (35 days) to slaughter (87 days). The health status of the animals was monitored, and mortality was recorded...
October 8, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28989564/diffusion-weighted-magnetic-resonance-imaging-of-liver-principles-clinical-applications-and-recent-updates
#20
REVIEW
Anuradha Shenoy-Bhangle, Vinit Baliyan, Hamed Kordbacheh, Alexander R Guimaraes, Avinash Kambadakone
Diffusion-weighted imaging (DWI), a functional imaging technique exploiting the Brownian motion of water molecules, is increasingly shown to have value in various oncological and non-oncological applications. Factors such as the ease of acquisition and ability to obtain functional information in the absence of intravenous contrast, especially in patients with abnormal renal function, have contributed to the growing interest in exploring clinical applications of DWI. In the liver, DWI demonstrates a gamut of clinical applications ranging from detecting focal liver lesions to monitoring response in patients undergoing serial follow-up after loco-regional and systemic therapies...
September 18, 2017: World Journal of Hepatology
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