keyword
https://read.qxmd.com/read/38537220/incidental-detection-of-synchronous-benign-hepatic-and-splenic-hemangiomas-on-18f-psma-pet-ct
#1
JOURNAL ARTICLE
Mohammed Hussain Alsaleh, Ali Saleh Alkhars, Mohammed Albensaad, Abedallatif Alsharif
A 51-year-old man with biochemical failure after brachytherapy for prostatic adenocarcinoma (PSA 5 μg/L rising to 6.45 μg/L) underwent a PSMA PET/CT scan. The scan revealed focal 18F-PSMA activity at the right apex suggestive of local residual or recurrent disease. In addition, 18F-PSMA images demonstrated 2 focal 18F-PSMA-avid liver and spleen lesions; both lesions were further evaluated by abdominal MRI, and the final radiological diagnosis was synchronous hepatic and splenic hemangiomas.
March 25, 2024: Clinical Nuclear Medicine
https://read.qxmd.com/read/38537180/perfluorobutane-sonazoid-contrast-enhanced-ultrasound-to-diagnose-hepatocellular-carcinoma-a-systematic-review-and-meta-analysis
#2
REVIEW
Yujia Chen, Wenjun Zhu, Yunyun Yi, Huali Cao, Fan Chen, Qinling Zhu
AIM: This meta-analysis aimed to assess the precision of Sonazoid contrast-enhanced ultrasound (CEUS) to distinguish hepatocellular carcinoma (HCC) from focal liver lesions (FLLs). MATERIAL AND METHODS: The Cochrane Library, Embase, PubMed, and Web of Science databases were systematically searched and checked for studies using Sonazoid CEUS to characterize HCC. A comprehensive meta-analysis was conducted, involving data pooling, subgroup analyses, meta-regression, and investigation of publication bias...
February 25, 2024: Medical Ultrasonography
https://read.qxmd.com/read/38515947/diagnostic-and-therapeutic-role-of-endoscopic-ultrasound-in-liver-diseases-a-systematic-review-and-meta-analysis
#3
JOURNAL ARTICLE
Eyad Gadour, Abeer Awad, Zeinab Hassan, Khalid Jebril Shrwani, Bogdan Miutescu, Hussein Hassan Okasha
BACKGROUND: In hepatology, the clinical use of endoscopic ultrasound (EUS) has experienced a notable increase in recent times. These applications range from the diagnosis to the treatment of various liver diseases. Therefore, this systematic review summarizes the evidence for the diagnostic and therapeutic roles of EUS in liver diseases. AIM: To examine and summarize the current available evidence of the possible roles of the EUS in making a suitable diagnosis in liver diseases as well as the therapeutic accuracy and efficacy...
February 21, 2024: World Journal of Gastroenterology: WJG
https://read.qxmd.com/read/38515044/malignancy-diagnosis-of-liver-lesion-in-contrast-enhanced-ultrasound-using-an-end-to-end-method-based-on-deep-learning
#4
JOURNAL ARTICLE
Hongyu Zhou, Jianmin Ding, Yan Zhou, Yandong Wang, Lei Zhao, Cho-Chiang Shih, Jingping Xu, Jianan Wang, Ling Tong, Zhouye Chen, Qizhong Lin, Xiang Jing
BACKGROUND: Contrast-enhanced ultrasound (CEUS) is considered as an efficient tool for focal liver lesion characterization, given it allows real-time scanning and provides dynamic tissue perfusion information. An accurate diagnosis of liver lesions with CEUS requires a precise interpretation of CEUS images. However,it is a highly experience dependent task which requires amount of training and practice. To help improve the constrains, this study aims to develop an end-to-end method based on deep learning to make malignancy diagnosis of liver lesions using CEUS...
March 21, 2024: BMC Medical Imaging
https://read.qxmd.com/read/38502435/exploring-the-low-dose-limit-for-focal-hepatic-lesion-detection-with-a-deep-learning-based-ct-reconstruction-algorithm-a-simulation-study-on-patient-images
#5
JOURNAL ARTICLE
Yongchun You, Sihua Zhong, Guozhi Zhang, Yuting Wen, Dian Guo, Wanjiang Li, Zhenlin Li
This study aims to investigate the maximum achievable dose reduction for applying a new deep learning-based reconstruction algorithm, namely the artificial intelligence iterative reconstruction (AIIR), in computed tomography (CT) for hepatic lesion detection. A total of 40 patients with 98 clinically confirmed hepatic lesions were retrospectively included. The mean volume CT dose index was 13.66 ± 1.73 mGy in routine-dose portal venous CT examinations, where the images were originally obtained with hybrid iterative reconstruction (HIR)...
March 19, 2024: J Imaging Inform Med
https://read.qxmd.com/read/38494820/-long-term-complete-response-by-capeox-plus-nivolumab-chemotherapy-for-postoperative-recurrence-of-gastric-cancer-a-case-report
#6
JOURNAL ARTICLE
Shinsuke Katsuyama, Toru Masuzawa, Keijiro Sugimura, Kiminori Yanagisawa, Go Shinke, Mitsuru Kinoshita, Ryo Ikeshima, Masayuki Hiraki, Yoshiaki Ohmura, Taishi Hata, Yutaka Takeda, Kohei Murata
A 73-year-old man underwent upper gastrointestinal endoscopy during a medical check-up that revealed a Type 2 lesion in the anterior wall of the gastric body. The biopsy confirmed tub2. A contrast-enhanced CT scan revealed focal wall thickening and lymphadenopathy in the gastric body. The patient was diagnosed with gastric cancer(M, ante, Type 2, T4aN1M0, Stage ⅢA). Laparotomy total gastrectomy D2 dissection and Roux-en-Y reconstruction were performed. Pathological results were tub1, int, INF b, ly0, v1, pT4aN0M0, pStage ⅡB...
March 2024: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://read.qxmd.com/read/38492004/enhancing-gadoxetic-acid-enhanced-liver-mri-a-synergistic-approach-with-deep-learning-caipirinha-vibe-and-optimized-fat-suppression-techniques
#7
JOURNAL ARTICLE
Hong Wei, Jeong Hee Yoon, Sun Kyung Jeon, Jae Won Choi, Jihyuk Lee, Jae Hyun Kim, Marcel Dominik Nickel, Bin Song, Ting Duan, Jeong Min Lee
OBJECTIVE: To investigate whether a deep learning (DL) controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA)-volumetric interpolated breath-hold examination (VIBE) technique can improve image quality, lesion conspicuity, and lesion detection compared to a standard CAIPIRINHA-VIBE technique in gadoxetic acid-enhanced liver MRI. METHODS: This retrospective single-center study included 168 patients who underwent gadoxetic acid-enhanced liver MRI at 3 T using both standard CAIPIRINHA-VIBE and DL CAIPIRINHA-VIBE techniques on pre-contrast and hepatobiliary phase (HBP) images...
March 16, 2024: European Radiology
https://read.qxmd.com/read/38457851/oa-gan-organ-aware-generative-adversarial-network-for-synthesizing-contrast-enhanced-medical-images
#8
JOURNAL ARTICLE
Yulin Yang, Jing Liu, Gan Zhan, Qingqing Chen, Fang Wang, Yinhao Li, Rahul Kumar Jain, Lanfen Lin, Hongjie Hu, Yen-Wei Chen
Contrast-enhanced computed tomography (CE-CT) images are vital
for clinical diagnosis of focal liver lesions (FLLs). However, the use of CE-CT
images imposes a significant burden on patients due to the injection of contrast
agents and extended shooting. Deep learning-based image synthesis models offer
a promising solution that synthesizes CE-CT images from non-contrasted CT
(NC-CT) images. Unlike natural images, medical image synthesis requires a
specific focus on certain organs or localized regions to ensure accurate diagnosis...
March 8, 2024: Biomedical Physics & Engineering Express
https://read.qxmd.com/read/38456971/artificial-intelligence-based-volumetric-assessment-of-the-bone-marrow-metabolic-activity-in-18-f-fdg-pet-ct-predicts-survival-in-multiple-myeloma
#9
JOURNAL ARTICLE
Christos Sachpekidis, Olof Enqvist, Johannes Ulén, Annette Kopp-Schneider, Leyun Pan, Elias K Mai, Marina Hajiyianni, Maximilian Merz, Marc S Raab, Anna Jauch, Hartmut Goldschmidt, Lars Edenbrandt, Antonia Dimitrakopoulou-Strauss
PURPOSE: Multiple myeloma (MM) is a highly heterogeneous disease with wide variations in patient outcome. [18 F]FDG PET/CT can provide prognostic information in MM, but it is hampered by issues regarding standardization of scan interpretation. Our group has recently demonstrated the feasibility of automated, volumetric assessment of bone marrow (BM) metabolic activity on PET/CT using a novel artificial intelligence (AI)-based tool. Accordingly, the aim of the current study is to investigate the prognostic role of whole-body calculations of BM metabolism in patients with newly diagnosed MM using this AI tool...
March 8, 2024: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/38447522/arterial-embolization-of-focal-nodular-hyperplasia-of-the-liver-a-case-report
#10
Hiba Ben Hassine, Mohamed Ali Chaouch, Maissa Jallali, Hanen Zenati, Besma Gafsi, Faouzi Noomen
INTRODUCTION AND IMPORTANCE: Focal nodular hyperplasia (FNH) is a benign liver lesion that can pose diagnostic and management dilemmas, especially when distinguishing it from other hypervascular hepatic lesions. The benign nature of FNH often makes conservative management a priority; however, intervention may be necessary in symptomatic cases or when diagnostic uncertainty exists. CASE PRESENTATION: A 19-year-old male presenting with abdominal pain, found to have a large 25 cm FNH lesion in the right lobe of the liver...
March 5, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38444652/benign-paediatric-liver-tumours-the-radiological-maze-demystified
#11
JOURNAL ARTICLE
Poonam Sherwani, Devasenathipathy Kandasamy, Raju Sharma, Prabudh Goel, Manisha Jana, Nellai Krishnan
UNLABELLED: The trajectory from the clinical identification of a benign liver mass to establishing a precise diagnosis is perplexing and arduous. Related contributory factors are that such lesions are encountered infrequently and that there is a nonavailability of dedicated paediatric radiologists in the developing world. The objective of this study was to review the spectrum of benign liver lesions in children and their typical imaging features. Cross-sectional imaging of all paediatric patients (< 18 years) with liver lesions (single and multiple) performed in the institute from 01 January 2018 to 01 January 2019 as well as those acquired at outside institutions and referred to the institute for management was included...
2024: SA journal of radiology
https://read.qxmd.com/read/38439817/rare-benign-focal-lesions-of-the-liver-report-of-2-cases-and-literature-review
#12
JOURNAL ARTICLE
Kristína Cmarková, Lenka Nosáková, Miroslav Pindura, Martin Vojtko, Peter Bánovčin, Juraj Miklušica
INTRODUCTION: Benign lesions of the liver are very common findings, usually randomly discovered, especially during examinations for other indications. The frequent use of imaging modalities may be responsible for the statistical increase in the incidence of these findings. CASE PRESENTATION: In this publication, we present the cases of 2 female patients with benign liver lesions, the occurrence of which is considered rare, and only a few dozen cases have been described worldwide...
2024: Case Reports in Gastroenterology
https://read.qxmd.com/read/38432117/disseminated-phaeohyphomycosis-due-to-cladophialophora-bantiana-in-an-immunocompetent-child
#13
Aakash Mahesan, Abin Sheref Mohammed, Gautam Kamila, Prashant Jauhari, Biswaroop Chakrabarty, Sumanta Das, Prasenjit Das, Vaishali Suri, Sudesh Gourav, Immaculata Xess, Atin Kumar, Sheffali Gulati
A 3-year-old boy presented with acute headache, vomiting and right focal clonic seizures without history of fever, joint pain or altered sensorium. Neuroimaging showed multifocal contrast enhancing lesions with significant perilesional edema. CECT chest and abdomen showed multiple variable sized nodules in the lungs and hypodense lesion in liver with mesenteric lymphadenopathy. There was persistent eosinophilia with maximum upto 35 %. Liver biopsy and brain biopsy revealed Cladophialophora bantiana. He was treated with IV liposomal amphotericin and voriconazole for 6 weeks with repeat neuroimaging showing more than 50 % resolution of the intracranial lesions...
February 24, 2024: Journal de Mycologie Médicale
https://read.qxmd.com/read/38415116/a-convenient-and-reproducible-protocol-for-acquisition-of-the-hepatocyte-phase-for-liver-function-impaired-patients-in-gadoxetic-acid-disodium-enhanced-magnetic-resonance-imaging
#14
JOURNAL ARTICLE
Chao Wang, Wei-Rong Sun, Ning Wu, Zhuang Zhang, Lai-Xing Zhang, Wan-Qing Yi, Xiao-Dong Yuan
BACKGROUND: The hepatocyte phase (HCP) in gadoxetic acid disodium (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) plays an important role in the detection and characterization of liver lesions, treatment planning, and liver function evaluation. However, the imaging protocol is complicated and time-consuming. This cross-sectional study aimed to develop a convenient and reproducible protocol for the HCP acquisition in Gd-EOB-DTPA-enhanced MRI. METHODS: A total of 107 patients were prospectively included and assigned to three groups based on Child-Pugh (CP) classification, with 37, 40, and 30 in the non-cirrhosis, CP A, and CP B groups, respectively...
February 1, 2024: Quantitative Imaging in Medicine and Surgery
https://read.qxmd.com/read/38412903/transthyretin-derived-amyloid-attr-and-sarcoidosis-does-attr-deposition-cause-a-granulomatous-inflammatory-response-in-older-adults-with-sarcoidosis
#15
JOURNAL ARTICLE
Shojiro Ichimata, Yukiko Hata, Kazuhiro Nomoto, Naoki Nishida
This study aimed to assess the frequency and association between transthyretin-derived (ATTR) amyloidosis and sarcoidosis in a large autopsy cohort including many cases of sudden cardiac death (SCD). We identified 73 sporadic ATTR amyloidosis cases and 11 sarcoidosis cases, among which we found two cases with concomitant ATTR amyloidosis and sarcoidosis (2.4% of all cases; 2.7% within the sporadic ATTR group). The first case involved a 92-year-old man who experienced SCD. In this patient's heart, we observed ATTR deposition and noncaseating epithelioid granulomas consistent with sarcoidosis...
February 25, 2024: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://read.qxmd.com/read/38411871/liver-imaging-and-pregnancy-what-to-expect-when-your-patient-is-expecting
#16
REVIEW
Giorgia Porrello, Roberto Cannella, Jacques Bernuau, Antoine Agman, Giuseppe Brancatelli, Marco Dioguardi Burgio, Valérie Vilgrain
Liver diseases in pregnancy can be specific to gestation or only coincidental. In the latter case, the diagnosis can be difficult. Rapid diagnosis of maternal-fetal emergencies and situations requiring specialized interventions are crucial to preserve the maternal liver and guarantee materno-fetal survival. While detailed questioning of the patient and a clinical examination are highly important, imaging is often essential to reach a diagnosis of these liver diseases and lesions. Three groups of liver diseases may be observed during pregnancy: (1) diseases related to pregnancy: intrahepatic cholestasis of pregnancy, pre-eclampsia, eclampsia, hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome, and acute fatty liver of pregnancy; (2) liver diseases that are more frequent during or exacerbated by pregnancy: acute herpes simplex hepatitis, Budd-Chiari syndrome, hemorrhagic hereditary telangiectasia, hepatocellular adenoma, portal vein thrombosis, and cholelithiasis; (3) coincidental conditions, including acute hepatitis, incidental focal liver lesions, metabolic dysfunction-associated steatotic liver disease, cirrhosis, hepatocellular carcinoma, liver abscesses and parasitosis, and liver transplantation...
February 27, 2024: Insights Into Imaging
https://read.qxmd.com/read/38406064/primary-invasive-ductal-carcinoma-of-the-breast-occurring-in-a-patient-with-a-history-of-hepatocellular-carcinoma-developing-from-focal-nodular-hyperplasia-a-case-report-and-literature-review
#17
Krizia-Ivana T Udquim, Nghi B Lam, Ellery Altshuler, Rick Y Lin
The risk of developing another primary malignancy after an initial liver cancer diagnosis is rare, and the management of multiple primary cancers is not typically discussed. Focal nodular hyperplasia (FNH) is considered a benign tumor, but there have been cases reported that describe hepatocellular carcinoma (HCC) arising from or within FNH. Here, we report a woman in her 70s who had a longstanding history of FNH, later found to be HCC upon resection, who also developed invasive ductal carcinoma. She had no family history of cancer and no genetic testing results were available...
January 2024: Curēus
https://read.qxmd.com/read/38391343/primary-hepatic-leiomyosarcoma-masquerading-as-focal-nodular-hyperplasia-of-liver-a-wolf-in-sheep-s-clothing
#18
JOURNAL ARTICLE
Ranajoy Ghosh, Aniket Halder, Ranjit K Nim, Sukanta Ray, Uttara Chatterjee
Primary hepatic leiomyosarcoma is a rare hepatic malignancy which requires exclusion of other primary site of origin. Clinical presentation and imaging of this tumor is nonspecific and mimics many other hepatic neoplasms. A 62-year-old female patient presents here with right hepatic mass with insidious onset and radiological features favoring a benign solid lesion suggestive of focal nodular hyperplasia. On right hepatectomy, an encapsulated mass identified about 11 cm in maximum dimension with pushing margin and central scar-like area...
July 19, 2023: Indian Journal of Pathology & Microbiology
https://read.qxmd.com/read/38360548/relationship-between-observation-time-and-detection-rate-of-focal-lesions-in-esophagogastroduodenoscopy-a-single-center-retrospective-study
#19
JOURNAL ARTICLE
Li Dong, Xiaodan Zhang, Yuting Xuan, Peiling Xiong, Yumei Ning, Bing Zhang, Fan Wang, Qiu Zhao, Jun Fang
BACKGROUND: Current studies have shown that longer observation time can improve neoplastic detection rate. This study aimed to clarify whether endoscopists with longer observation times can detect more focal lesions. METHODS: Based on the mean examination time for Esophagogastroduodenoscopy (EGD) without biopsy, endoscopists were divided into fast and slow groups, and the detection rate of focal lesions was compared between the two groups. Univariate analysis, multivariate analysis and restricted cubic spline were used to explore the factors of focal lesion detection rate...
February 15, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38350630/development-evaluation-and-overview-of-standardized-training-phantoms-for-abdominal-ultrasound-guided-interventions
#20
JOURNAL ARTICLE
Max Seitzinger, Franziska Gnatzy, Sabine Kern, Ralf Steinhausen, Jana Klammer, Tobias Schlosser, Valentin Blank, Thomas Karlas
PURPOSE: Ultrasound (US) represents the primary approach for abdominal diagnosis and is regularly used to guide diagnostic and therapeutic interventions (INVUS). Due to possible serious INVUS complications, structured training concepts are required. Phantoms can facilitate teaching, but their use is currently restricted by complex manufacturing and short durability of the materials. Hence, the aim of this study was the development and evaluation of an optimized abdominal INVUS phantom...
February 13, 2024: Ultraschall in der Medizin
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