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Soultana Meditskou, Panagiotis Mylonakis, Dimitrios Giannoglou, Thomas Zegkos, Efstathios Pagourelias, Nikolaos Protonotarios, Georgios K Efthimiadis, Haralambos Karvounis
No abstract text is available yet for this article.
November 1, 2016: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
Finja Jockenhöfer, Katharina Herberger, Jörg Schaller, Katja Christina Hohaus, Maren Stoffels-Weindorf, Philipp Al Ghazal, Matthias Augustin, Joachim Dissemond
EINLEITUNG: Das Pyoderma gangraenosum (PG) ist eine seltene, inflammatorische destruktiv-ulzerierende neutrophile Erkrankung mit weitgehend unklarer Pathophysiologie. MATERIAL UND METHODIK: In dieser Studie wurden die potenziell relevanten Kofaktoren und Begleiterkrankungen von Patienten mit PG aus drei dermatologischen Wundzentren in Deutschland differenziert ausgewertet. ERGEBNISSE: Von den insgesamt 121 analysierten Patienten waren Frauen (66,9 %) häufiger betroffen als Männer...
October 2016: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
Markus Zutt, Hagen Rudolph, Kjell Matthias Kaune, Werner Wosniok, Ulrich Gärtner, Rainer Linke
HINTERGRUND: Kardiale Komorbiditäten bei Patienten mit Psoriasis stehen seit Jahren im Fokus. Ziel dieser Arbeit war es, im Rahmen einer Pilotstudie die Myokardszintigraphie als mögliche Früherkennungsmethode zu evaluieren. PATIENTEN UND METHODIK: Es wurden bei insgesamt 50 kardial asymptomatischen Patienten mit einer Psoriasis der Haut verschiedene Begleiterkrankungen erfasst. Dabei kam zur Erkennung von kardialem Risiko/ belastungsinduzierter Ischämie die Myokardszintigraphie zum Einsatz...
October 2016: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
Clarissa Schulze Zur Wiesch, Anne Lautenbach, Jens Aberle
Indication for bariatric or metabolic surgery depends primarily on body mass index. Recent study results however suggest, that other markers are more reliable predictors of metabolic success. A revision of indication criteria is therefore necessary especially for surgical therapy of type 2 diabetes mellitus. Postoperative management should include screening for postbariatric hypoglycemia and bone density. Furthermore psychologic surveillance is recommended.
September 2016: Deutsche Medizinische Wochenschrift
Finja Jockenhöfer, Knut Kröger, Joachim Klode, Regina Renner, Cornelia Erfurt-Berge, Joachim Dissemond
HINTERGRUND: Die Necrobiosis lipoidica (NL) ist eine seltene, granulomatöse inflammatorische Erkrankung der Haut unklarer Pathophysiologie mit potentieller Assoziation zum Diabetes mellitus. Weitere relevante Kofaktoren und Komorbiditäten wurden bislang kontrovers diskutiert. PATIENTEN UND METHODIK: Differenziert ausgewertet wurden die Diagnosis-related-Groups (DRG)-Daten aller Patienten, die 2012 stationär in Deutschland behandelt und mit der Haupt- und Nebendiagnose NL kodiert wurden...
March 2016: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
Sandra Haider, Thomas Lamprecht, Daniel Dick, Christian Lackinger
Physical inactivity is one of the major risk factors for people to become overweight or obese. To achieve a substantial health benefit, adults should do at least 150 min of moderate or 75 min of high intensity aerobic activity per week and additionally they should do muscle strengthening exercises. This recommendation represents the lower limit and not the optimum. To loose body weight a significantly higher level of physical activity is required. Exercise programs can play an important part to reach the required level of health-enhancing physical activity...
March 2016: Wiener Medizinische Wochenschrift
Christoffer Gebhardt, Ramtin Lichtenberger, Jochen Utikal
HINTERGRUND UND ZIELE: Die Bestimmung der S100B-Serumkonzentration ist eine Standardmethode zur Überwachung von Patienten mit fortgeschrittenem malignem Melanom zur Unterscheidung zwischen progressiver und nicht progressiver Krankheit. Falsch-positive Befunde verursachen unnötiges Leid bei den Patienten und führen zu einem Anstieg kostspieliger Diagnosen. Aus diesem Grund analysierten wir beschriebene Begleitkrankheiten als mögliche Quellen überschüssiger S100B-Freisetzung. PATIENTENUND METHODEN: In einer single-center-Studie wurde die Serumkonzentration von S100B in 2...
February 2016: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
Yan-Hong Liang, Jun Zhu, Ding-Rong Zhong, Dong-Yan Hou, Gui-Ling Ma, Zhi-Yong Zhang, Lin Zhang
BACKGROUND: The principal aim of this study was to investigate the clinical, epidemiological and pathologic features for a series of 79 cases of adipositas cordis sudden death. METHODS: We analyzed clinical and autopsy pathological features of 79 patients (43 females and 36 males) with adipositas cordis who died suddenly between 1975 and 2010. Data were extracted from China National Knowledge Infrastructure and Wan Fang Database. RESULTS: The average age of the 79 cases was 36...
2015: International Journal of Clinical and Experimental Pathology
C Stroh, R Weiner, S Wolff, C Knoll, M de Zwaan, T Manger, Kompetenzzentrum Adipositas
BACKGROUND: The current situation in obesity and metabolic surgery since January 2005 has been investigated with the help of the quality assurance study on surgical therapy for obesity = German Bariatric Surgery Registry (GBSR). The data were acquired and analysed in cooperation with the Institute for Quality Assurance in Surgical Medicine at the Otto-von-Guericke University. METHODS: Data acquisition was done with the help of an online database. On a voluntary basis, all obesity and metabolic surgical interventions since 2005 have been recorded...
June 2015: Zentralblatt Für Chirurgie
R K Chilukoti, A Giese, W Malenke, G Homuth, A Bukowska, A Goette, S B Felix, J Kanaan, H-G Wollert, K Evert, S Verheule, P Jais, S N Hatem, U Lendeckel, C Wolke
PURPOSE: Atrial fibrillation (AF) has been associated with increased volumes of epicardial fat and atrial adipocyte accumulation. Underlying mechanisms are not well understood. This study aims to identify rapid atrial pacing (RAP)/AF-dependent changes in atrial adipocyte/adipositas-related gene expression (AARE). METHODS: Right atrial (RA) and adjacent epicardial adipose tissue (EAT) samples were obtained from 26 patients; 13 with AF, 13 in sinus rhythm (SR). Left atrial (LA) samples were obtained from 9 pigs (5 RAP, 4 sham-operated controls)...
2015: International Journal of Cardiology
Marion Flechtner-Mors, Hannelore Neuhauser, Thomas Reinehr, Hans-Peter Roost, Susanna Wiegand, Wolfgang Siegfried, Karl Zwiauer, Esther Molz, Reinhard W Holl
The aim of this study was to determine the prevalence of hypertension in overweight or obese pediatric subjects using different national or international references, which are based either on the entire population or on normal weight children only: 188 centers from Germany, Austria, and Switzerland participated in the Adipositas Patienten Verlaufsbeobachtung initiative. Data from 57,915 children aged 6 to 18 years who are overweight or obese were used to determine the prevalence of prehypertension and hypertension based on Second Task Force, European pooled data, Fourth Report all and Fourth Report nonoverweight, or German Health Interview and Examination Survey for Children and Adolescents (KiGGS) references...
June 1, 2015: American Journal of Cardiology
K A Polyzos, D F J Ketelhuth
Coronary heart disease and stroke, the deadliest forms of cardiovascular disease (CVD), are mainly caused by atherosclerosis, a chronic inflammatory disease of the artery wall driven by maladaptive immune responses in the vessel wall. Various risk factors for CVD influence this pathogenic process, including diabetes mellitus, hypertension, dyslipidaemia, and obesity. Indoleamine 2,3-dioxygenase (IDO), an enzyme catalyzing the rate-limiting step in the kynurenine pathway of tryptophan degradation, is strongly induced by inflammation in several tissues, including the artery wall...
2015: Hämostaseologie
Dirk Bareiss, Michael Dickenmann, Felix Burkhalter
The prevalence of CKD increases with old age. The increase of risk factors for the development of CKD such as hypertension, diabetes and adipositas is essentially responsible for this. For the treating physician it is therefore important to diagnose CKD early to slow its progression. Physiological aging of the kidney is responsible for the development of functional impairments in the elderly. Electrolyte disorders and hemodynamically caused perfusion deficits are more frequent in old age and are often caused by medication...
December 10, 2014: Praxis
Christian Muschitz, Roland Kocijan, Christina Marterer, Arastoo Rahbar Nia, Gabriela Katharina Muschitz, Heinrich Resch, Peter Pietschmann
CONTEXT: The role of sclerostin as a key regulator of bone formation remains unknown after Roux-en-Y gastric bypass (RYGB) or laparoscopic sleeve gastrectomy (SG). OBJECTIVES: The study objectives were evaluation of sclerostin and Dickkopf-1 (DKK-1) serum levels after surgery and correlations with bone turnover markers (P1NP, CTX), parathyroid hormone (iPTH) and areal bone mineral density (BMD), changes at total body, lumbar spine and total hip. DESIGN AND SETTING: This was a prospective observational single-center two-arm study in premenopausal women with acute adipositas over 24 months...
March 2015: Journal of Clinical Endocrinology and Metabolism
Peter Kovacs
No abstract text is available yet for this article.
September 2014: Deutsche Medizinische Wochenschrift
C Stroh, R Weiner, S Wolff, C Knoll, T Manger
BACKGROUND: Increasing numbers of interventions for obesity and metabolic surgery have led to an increase of primary bariatric operations as well as redo operations and revisional surgery after various primary bariatric procedures. Evidence-based guidelines for indications and choice of procedure for revisional surgery do not currently exist. AIM: The spectrum of various revisional and redo operations following standard operative procedures for obesity and metabolic surgery is presented based on current data from the German bariatric surgery registry (GBSR, German nationwide survey on quality assurance in bariatric surgery) and a literature search...
April 2015: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
C Stroh, B Wilhelm, R Weiner, K Ludwig, F Benedix, C Knoll, H Lippert, T Manger, Kompetenznetz Adipositas
BACKGROUND: Since January 2005, the situation of metabolic and obesity surgery in Germany has been constantly evaluated by the German Bariatric Surgery Registry (GBSR). Data registration is performed using an internet online database with prospective data collection. All registered data were analysed in cooperation with the Institute of Quality Assurance at the Otto-von-Guericke University Magdeburg. METHODS: Data collection includes primary and revision/redo-procedures...
February 2016: Zentralblatt Für Chirurgie
Marion Flechtner-Mors, Susanna Wiegand, Ines Gellhaus, Heidi Siefken-Kaletka, Kurt Widhalm, Thomas Reinehr, Hans-Peter Roost, Georg Leipold, Ulrike Hoffmeister, Reinhard W Holl
OBJECTIVE: The aim of the study was to analyze the adherence to current guidelines for co-morbidity screening in overweight and obese pediatric patients participating in the Adipositas-Patienten-Verlaufsdokumentation (APV) initiative in three German-speaking countries. METHODS: APV database: 181 centers from Germany, Austria and Switzerland, specialized in obesity care, contributed standardized, anonymous data of medical examinations from 65,397 patients performed between 2000 and 2010...
2013: Obesity Facts
Nadine A Binai, Gert Carra, Johannes Löwer, Roswitha Löwer, Silja Wessler
In postmenopausal women, adipositas represents a serious risk factor for cancer development and progression. White adipose tissue secretes the 16 kDa hormone leptin which plays a key role in the regulation of appetite and metabolism. An increasing number of reports indicate that leptin also interferes with signal transduction pathways implicated in the development of breast cancer. In our previous study, we identified the estrogen receptor alpha (ERα) as a relevant enhancer of leptin-induced signal transduction leading to transactivation of signal transducer and activator of transcription 3 (Stat3)...
October 2013: Endocrine
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