keyword
https://read.qxmd.com/read/38538172/timing-of-complete-multivessel-revascularization-in-patients-presenting-with-non-st-segment-elevation-acute%C3%A2-coronary-syndrome
#21
JOURNAL ARTICLE
Jacob J Elscot, Hala Kakar, Paola Scarparo, Wijnand K den Dekker, Johan Bennett, Carl E Schotborgh, René van der Schaaf, Manel Sabaté, Raúl Moreno, Koen Ameloot, Rutger J van Bommel, Daniele Forlani, Bert Van Reet, Giovanni Esposito, Maurits T Dirksen, Willem P T Ruifrok, Bert R C Everaert, Carlos Van Mieghem, Eduardo Pinar, Fernando Alfonso, Paul Cummins, Mattie Lenzen, Salvatore Brugaletta, Joost Daemen, Eric Boersma, Nicolas M Van Mieghem, Roberto Diletti
BACKGROUND: Complete revascularization of the culprit and all significant nonculprit lesions in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS) and multivessel disease (MVD) reduces major adverse cardiac events, but optimal timing of revascularization remains unclear. OBJECTIVES: This study aims to compare immediate complete revascularization (ICR) and staged complete revascularization (SCR) in patients presenting with NSTE-ACS and MVD...
March 25, 2024: JACC. Cardiovascular Interventions
https://read.qxmd.com/read/38537671/socioeconomic-and-ethnic-disparities-in-the-process-of-care-and-outcomes-among-cancer-patients-with-acute-coronary-syndrome
#22
REVIEW
Mohamed Mohamed, Arjun K Ghosh, Amitava Banerjee, Mamas Mamas
Cancer and acute coronary syndrome (ACS) are the leading causes of morbidity and mortality globally, with many shared risk factors between both conditions. There are several challenges to the management of patients with cancer presenting with ACS due to their higher baseline risk profile, the complexities of their cancer-related therapies and prognosis, and their higher risk of adverse outcomes after ACS. Although previous studies have demonstrated disparities in the care of both cancer and ACS among patients from ethnic minorities and socioeconomic deprivation, there is limited evidence around the magnitude of such disparities specifically in cancer patients presenting with ACS...
March 25, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38537614/correction-to-nationwide-time-trends-in-patients-hospitalized-for-acute-coronary-syndrome-a-worrying-generational-and-social-effect-among-women
#23
(no author information available yet)
No abstract text is available yet for this article.
March 27, 2024: European Journal of Preventive Cardiology
https://read.qxmd.com/read/38534886/drug-drug-interactions-of-fxi-inhibitors-clinical-relevance
#24
REVIEW
Nicola Ferri, Elisa Colombo, Alberto Corsini
Inhibitors of the factor FXI represent a new class of anticoagulant agents that are facing clinical approval for the treatment of acute coronary syndrome (ACS), venous thromboembolism (VTE), and stroke prevention of atrial fibrillation (AF). These new inhibitors include chemical small molecules (asundexian and milvexian), monoclonal antibodies (abelacimab, osocimab, and xisomab), and antisense oligonucleotides (IONIS-FXIRX and fesomersen), and thus, they have very peculiar and different pharmacokinetic and pharmacodynamic properties...
March 21, 2024: Hematology Reports
https://read.qxmd.com/read/38533994/mobile-phone-text-messaging-for-medication-adherence-in-secondary-prevention-of-cardiovascular-disease
#25
REVIEW
Julie Redfern, Qiang Tu, Karice Hyun, Matthew A Hollings, Nashid Hafiz, Clara Zwack, Caroline Free, Pablo Perel, Clara K Chow
BACKGROUND: Cardiovascular diseases (CVDs) are the leading cause of death globally, accounting for almost 18 million deaths annually. People with CVDs have a five times greater chance of suffering a recurrent cardiovascular event than people without known CVDs. Although drug interventions have been shown to be cost-effective in reducing the risk of recurrent cardiovascular events, adherence to medication remains suboptimal. As a scalable and cost-effective approach, mobile phone text messaging presents an opportunity to convey health information, deliver electronic reminders, and encourage behaviour change...
March 27, 2024: Cochrane Database of Systematic Reviews
https://read.qxmd.com/read/38533983/risk-of-death-and-cardiovascular-events-in-asian-patients-with-atrial-fibrillation-and-chronic-obstructive-pulmonary-disease-a-report-from-the-prospective-aphrs-registry
#26
JOURNAL ARTICLE
Tommaso Bucci, Giulio Francesco Romiti, Alena Shantsila, Wee-Siong Teo, Hyung-Wook Park, Wataru Shimizu, Bernadette Corica, Marco Proietti, Hung-Fat Tse, Tze-Fan Chao, Frederick Frost, Gregory Y H Lip
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is associated with an increased risk of adverse events in patients with atrial fibrillation (AF); however, few data are available on this topic in Asian populations. METHODS AND RESULTS: Prospective observational study conducted on patients with AF enrolled in the Asia-Pacific Heart Rhythm Society (APHRS) AF Registry. The diagnosis of COPD was based on data reported in the case report form by the investigators...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533174/impact-of-temperature-and-atmospheric-pressure-on-hospitalizations-of-patients-presenting-with-acute-coronary-syndrome
#27
JOURNAL ARTICLE
Naltin Shuka, Andri Cabeli, Leonard Simoni, Mirald Gina, Ledjana Kondi, Edvin Dado
AIM:  This study aims to investigate the impact of temperature and atmospheric pressure on hospitalizations of patients with acute coronary syndrome (ACS). MATERIALS AND METHODS: This is a retrospective, observational, analytical study conducted in a single center, University Hospital Center "Mother Teresa," Tirana, Albania, in the period January-December 2018. This study included 1,165 patients with ACS, who performed urgent coronary angiography, from January 2018 to December 2018...
February 2024: Curēus
https://read.qxmd.com/read/38532820/incidence-and-predictors-of-acute-coronary-syndrome-in-patients-on-maintenance-hemodialysis-a-prospective-cohort-study
#28
JOURNAL ARTICLE
Ju-Yin Hsu, Chih-Kuo Lee, Shou-Yung Chaung, Chi-Hung Cheng, Li-Pei Dai, Mu-Yang Hsieh, Chung-Wei Yang, Chih-Cheng Wu
BACKGROUND: Cardiovascular diseases are the leading cause of death among patients on hemodialysis, with approximately 40% of the cardiovascular deaths linked to acute coronary syndrome. We aimed to investigate the incidence and risk factors of acute coronary syndrome in patients undergoing hemodialysis. METHODS: Patients undergoing hemodialysis were prospectively enrolled from January 2018. Data regarding hospitalization due to acute coronary syndrome were collected at 3-month intervals through December 31, 2021...
March 2024: Acta Cardiologica Sinica
https://read.qxmd.com/read/38532263/diagnostic-and-prognostic-value-of-cardiac-troponins-in-emergency-department-patients-presenting-after-a-fall-a-prospective-multicenter-study
#29
JOURNAL ARTICLE
Tanguy Espejo, Lukas Terhalle, Alexandra Malinovska, Henk B Riedel, Laura Arntz, Livia Hafner, Karen Delport-Lehnen, Joanna Zuppinger, Nicolas Geigy, Jörg Leuppi, Rajan Somasundaram, Roland Bingisser, Christian H Nickel
BACKGROUND: Emergency department (ED) presentations after a ground-level fall (GLF) are common. Falls were suggested to be another possible presenting feature of a myocardial infarction (MI), as unrecognized MIs are common in older adults. Elevated high-sensitivity cardiac troponin (hs-cTn) concentrations could help determine the etiology of a GLF in ED. We investigated the prevalence of both MI and elevated high-sensitivity cardiac troponin T (hs-cTnT) and I (hs-cTnI), as well as the diagnostic accuracy of hs-cTnT and hs-cTnI regarding MI, and their prognostic value in older ED patients presenting after a GLF...
March 26, 2024: Academic Emergency Medicine
https://read.qxmd.com/read/38529950/european-practices-on-antithrombotic-management-during-percutaneous-mechanical-circulatory-support-in-adults-a-survey-of-the-association-for-acute-cardiovascular-care-acvc-of-the-esc-and-the-european-branch-of-the-extracorporeal-life-support-organization-euroelso
#30
JOURNAL ARTICLE
Charlotte J Van Edom, Justyna Swol, Thomas Castelein, Mario Gramegna, Kurt Huber, Sergio Leonardi, Thomas Mueller, Federico Pappalardo, Susanna Price, Hannah Schaubroeck, Benedikt Schrage, Guido Tavazzi, Leen Vercaemst, Pascal Vranckx, Christophe Vandenbriele
BACKGROUND: Bleeding and thrombotic complications compromise outcomes in patients undergoing percutaneous mechanical circulatory support (pMCS) with veno-arterial extracorporeal membrane oxygenation (V-A ECMO) and/or microaxial flow pumps like the Impella™. Antithrombotic practices are an important determinant of the coagulopathic risk, but standardization in the antithrombotic management during pMCS is lacking. This survey outlines European practices in antithrombotic management in adults on pMCS, making an initial effort to standardize practices, inform future trials, and enhance outcomes...
March 26, 2024: European Heart Journal. Acute Cardiovascular Care
https://read.qxmd.com/read/38529334/stress-hyperglycemia-and-poor-outcomes-in-patients-with-st-elevation-myocardial-infarction-a-systematic-review-and-meta-analysis
#31
Abdul Hakim Alkatiri, Nurul Qalby, Idar Mappangara, Ahmad Taufik F Zainal, Maarten J Cramer, Pieter A Doevendans, Andriany Qanitha
BACKGROUND: Hyperglycemia, characterized by elevated blood glucose levels, is frequently observed in patients with acute coronary syndrome, including ST-elevation myocardial infarction (STEMI). There are conflicting sources regarding the relationship between hyperglycemia and outcomes in STEMI patients. We aimed to compile evidence to assess the association between hyperglycemia and adverse outcomes. METHODS: We conducted a comprehensive search for articles on PubMed and Embase using search strategies which yielded 4,061 articles...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38528542/association-of-sodium-glucose-cotransporter-2-inhibitors-with-risk-of-major-adverse-cardiovascular-events-in-type-2-diabetes-patients-with-acute-coronary-syndrome-a-propensity-score%C3%A2-matched-analysis
#32
JOURNAL ARTICLE
Tao Liu, Zeyuan Fan, Bing Xiao, Chang He, Shicong Wang
BACKGROUND: This study aimed to investigate the association of sodium-glucose cotransporter 2 inhibitors (SGLT2i) use with cardiovascular (CV) clinical outcomes in type 2 diabetes (T2D) patients with acute coronary syndrome (ACS). METHODS: Data of T2D patients hospitalized for ACS at Civil Aviation General Hospital from January 2019 to December 2022 were collected. Based on SGLT2i use or not, patients were stratified as SGLT2i group and SGLT2i-free group. A 1:1 nearest-neighbor propensity score-matched (PSM) was performed to adjust for the confounding factors and facilitate the robust comparisons between groups...
March 25, 2024: Cardiovascular Diabetology
https://read.qxmd.com/read/38526859/telomerase-activity-and-htert-gene-expression-in-patients-with-acute-coronary-syndrome-and-stable-coronary-artery-disease
#33
JOURNAL ARTICLE
Mehmet Kilinc, Oguz Kilic, Mucahit Secme, Cihan Ilyas Sevgican, Ibrahim Oguz, Hande Senol, Yavuz Dodurga, Gokay Nar, Ismail Dogu Kilic
BACKGROUND: In this study, we aimed to examine the telomerase activity and hTERT gene expression in patients with acute coronary syndrome (ACS) and those with stable coronary artery disease (SCAD) and compare the results to controls. Additionally, we compared overall mortality rates relative to the telomerase activity. METHODS: A total of 211 patients (78 ACS and 71 SCAD patients) were included in the study. The telomerase concentration was measured by ELISA and used to determine telomerase activity...
2024: Bratislavské Lekárske Listy
https://read.qxmd.com/read/38526603/global-longitudinal-strain-in-long-term-risk-prediction-after-acute-coronary-syndrome-an-investigation-of-added-prognostic-value-to-ejection-fraction
#34
JOURNAL ARTICLE
Joel Lenell, Bertil Lindahl, David Erlinge, Tomas Jernberg, Jonas Spaak, Tomasz Baron
AIMS: This study aimed to investigate the additional value of global longitudinal strain (GLS) on top of left ventricular ejection fraction (LVEF) in long-term risk prediction of combined death and heart failure (HF) re-hospitalization after acute coronary syndrome (ACS). METHOD AND RESULTS: This retrospective study included patients admitted with ACS between 2008 and 2014 from the three participating university hospitals. LVEF and GLS were assessed at a core lab from images acquired during the index hospital stay...
March 25, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38526359/-ten-questions-about-myocardial-infarction-with-non-obstructed-coronary-arteries
#35
JOURNAL ARTICLE
Giuseppe Ciliberti, Luca Bergamaschi, Pasquale Paolisso, Filippo Zilio, Carmine Pizzi
The term "MINOCA" refers to myocardial infarction with non-obstructed coronary arteries and has been used to define acute myocardial infarction with no angiographic evidence of significant epicardial coronary artery stenosis. Patients with MINOCA represent a rather heterogeneous group of acute coronary syndrome, and this may account for the wide variation in the incidence of MINOCA in different studies. Several pathogenic mechanisms have been suggested to underlie MINOCA, but the condition continues to represent a diagnostic and therapeutic challenge for the cardiologist...
April 2024: Giornale Italiano di Cardiologia
https://read.qxmd.com/read/38525068/value-of-absolute-eosinophil-count-in-patients-with-acute-coronary-syndrome-undergoing-percutaneous-coronary-intervention
#36
JOURNAL ARTICLE
Yufei Wang, Xiaoteng Ma, Zhiqiang Yang, Qiuxuan Li, Yujie Zhou, Fei Gao, Zhijian Wang
BACKGROUND AND AIMS: Elevated eosinophils typically indicate hypersensitive inflammation; however, their involvement in cardiovascular events remains incompletely understood. We investigated the association between the absolute eosinophil count (AEC) and major adverse cardiovascular and cerebrovascular events (MACCEs) in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI). Additionally, we determine whether the integration of AEC with the SYNTAX II score could improve predictive ability...
2024: International Journal of General Medicine
https://read.qxmd.com/read/38524515/significant-risk-factors-for-intensive-care-unit-acquired-weakness-a-processing-strategy-based-on-repeated-machine-learning
#37
JOURNAL ARTICLE
Ling Wang, Deng-Yan Long
BACKGROUND: Intensive care unit-acquired weakness (ICU-AW) is a common complication that significantly impacts the patient's recovery process, even leading to adverse outcomes. Currently, there is a lack of effective preventive measures. AIM: To identify significant risk factors for ICU-AW through iterative machine learning techniques and offer recommendations for its prevention and treatment. METHODS: Patients were categorized into ICU-AW and non-ICU-AW groups on the 14th day post-ICU admission...
March 6, 2024: World Journal of Clinical Cases
https://read.qxmd.com/read/38524235/associations-between-inflammatory-and-angiogenic-proteomic-biomarkers-and-cardiovascular-events-and-mortality-in-relation-to-kidney-function
#38
JOURNAL ARTICLE
Barbara Salzinger, Kristina Lundwall, Marie Evans, Josefin Mörtberg, Håkan Wallén, Tomas Jernberg, Thomas Kahan, Pia Lundman, Per Tornvall, David Erlinge, Bertil Lindahl, Tomasz Baron, Melinda Rezeli, Jonas Spaak, Stefan H Jacobson
BACKGROUND: The links between chronic kidney disease (CKD) and the high burden of cardiovascular disease remain unclear. We aimed to explore the association between selected inflammatory and angiogenic biomarkers, kidney function and long-term outcome in patients with an acute coronary syndrome (ACS) and to test the hypothesis that CKD status modifies this association. METHODS: A total of 1293 ACS patients hospitalized between 2008 and 2015 were followed until 31 December 2017...
March 2024: Clinical Kidney Journal
https://read.qxmd.com/read/38524096/severity-of-coronary-artery-disease-by-friesinger-score-among-women-with-acute-coronary-syndrome-in-a-tertiary-care-hospital-in-bangladesh
#39
JOURNAL ARTICLE
Ayesha Siddika, Fazila-Tun-Nesa Malik, Md Kalimuddin, Nahidul Hasan, Nazir Ahmed, Mohammad Badiuzzaman, Dhiman Banik, Tawfiq S Huq, Mir Ishraquzzaman, Faria Rahman
BACKGROUND: The chance of coronary artery disease (CAD) is much higher in women who have gone through menopause than in those who have not, owing to hormonal defense against atherosclerosis. More advanced CAD and several comorbidities were observed in postmenopausal women. Nevertheless, there is a paucity of information comparing the angiographic severity of acute coronary syndrome (ACS) in premenopausal and postmenopausal women of different ages. This research sought to determine the Friesinger score's use in evaluating the degree of CAD in premenopausal and postmenopausal women with ACS...
February 2024: Curēus
https://read.qxmd.com/read/38524037/altered-mental-status-in-the-setting-of-thrombotic-thrombocytopenic-purpura-ttp-and-spontaneous-coronary-artery-dissection-scad-a-case-report-and-literature-review
#40
Esmirna Perez, Nehemias Guevara, Jordan Smith, Ricardo Velasquez
Altered mental status (AMS) is a common condition encountered in daily practice. Finding the cause is essential for treatment, but sometimes this may be challenging. Spontaneous coronary artery dissection (SCAD) is frequently underdiagnosed and is a potentially fatal cause of acute coronary syndrome. Clinical presentation depends on the extent of SCAD, ranging from unstable angina to sudden death. AMS has not been reported with this condition, but it may be possible in hypoperfusion states. Thrombotic thrombocytopenic purpura (TTP) is part of the microangiopathic hemolytic anemia (MAHA) spectrum, presenting with AMS as the cardinal symptom...
February 2024: Curēus
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