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Exposure keratopathy

Ju-Hyang Lee, Orapan Aryasit, Yoon-Duck Kim, Kyung In Woo, Llewellyn Lee, Owen N Johnson
BACKGROUND/AIMS: Surgical treatments for the correction of congenital ptosis with poor levator function, including frontalis suspension or maximal levator resection, remain controversial. We evaluated the postoperative surgical and cosmetic outcomes after maximal levator resection for unilateral congenital ptosis with poor levator function. METHODS: A retrospective, interventional case series was performed. A total of 243 patients with 243 eyelids (210 unilateral and 33 bilateral asymmetric ptosis) who underwent unilateral maximal levator resection were included...
September 6, 2016: British Journal of Ophthalmology
Vijay Kumar Wagh, Wei S Lim, Nikhil C Cascone, A M S Morley
Exposure keratopathy may result in ocular surface dryness, pain, corneal ulceration and loss of vision. Upper eyelid loading is an effective surgical treatment for paralytic lagophthalmos but has been criticised for complications of implant exposure and poor cosmesis. We therefore reviewed the safety and efficacy of our technique of upper eyelid post-septal loading for exposure keratopathy in this context. A retrospective case notes analysis was undertaken of 38 patients who had upper eyelid loading, all with post-septal weight placement, for correction of lagophthalmos...
October 2016: Orbit
Jeffrey D Sharon, Courtney L Kraus, Matthew Ehrenburg, Heather M Weinreich, Howard W Francis
OBJECTIVE: To analyze the rate of corneal complications after lateral skull base surgery, and the relative risk of each potential contributing factor. STUDY DESIGN: Retrospective cohort study. SETTING: Tertiary care center. PATIENTS: Adult patients who had undergone lateral skull base surgery involving an otolaryngologist at our institution from 2007 to 2015. INTERVENTION: None. MAIN OUTCOME MEASURE: Relative risk (RR) for each potential contributing factor to corneal complications...
September 2016: Otology & Neurotology
A Bajor, C P Lang, E Bültmann, C Framme, K Hufendiek
Bacterial orbital cellulitis is a life-threatening infection of the postseptal orbital tissue. It can occur in the context of sinusitis, particularly in children and adolescents. Ocular complications include exposure keratopathy, increased intraocular pressure, occlusion of the central retinal artery or vein and optic neuropathy. Rarely, a subperiosteal abscess can occur, and osteomyelitis can lead to spread of the infection to the cerebrum. A rapid diagnosis and targeted therapy are essential for saving the eye as well as the life of the patient...
June 17, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
Patrick M McNutt, Kaylie M Tuznik, Elliot J Glotfelty, Marian R Nelson, Megan E Lyman, Tracey A Hamilton
Corneal injuries resulting from ocular exposure to sulfur mustard (SM) vapor are the most prevalent chemical warfare injury. Ocular exposures exhibit three distinct, dose-dependent clinical trajectories: complete injury resolution, immediate transition to a chronic injury, or apparent recovery followed by the subsequent development of persistent ocular manifestations. These latter two trajectories include a constellation of corneal symptoms that are collectively known as mustard gas keratopathy (MGK). The etiology of MGK is not understood...
June 2016: Annals of the New York Academy of Sciences
Yao Fu, Chunyi Shao, Wenjuan Lu, Jin Li, Xianqun Fan
AIM: The aim of this study was to evaluate the long-term outcome when a free tarsomarginal graft is used to repair a large congenital coloboma in patients with a Tessier number 10 cleft. MATERIALS AND METHODS: This was a retrospective, interventional case series. The medical records were reviewed for five children (six eyes) diagnosed as having Tessier number 10 cleft with large upper eyelid defects and symblepharon. These children were referred to the Department of Ophthalmology of Shanghai Ninth People's Hospital, between May 2007 and December 2012...
August 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
O Kousha, Z Kousha, J Paddle
No abstract text is available yet for this article.
December 2015: Intensive Care Medicine Experimental
Dejan M Rašić, Miroslav Knežević, Tatjana Terzić, Gordana Vlajković
A 66-year-old man developed a slowly enlarging, bilateral, painless, periorbital and orbital swelling with ptosis, non-axial proptosis, chemosis, exposure keratopathy and decreased vision in both eyes. He had fever, night sweats, and weight loss (B-symptoms), along with lymphadenopathy and elevated serum lactate dehydrogenase, with no prior history of lymphoma. A transpalpebral incisional biopsy revealed a rare case of mantle cell lymphoma of blastoid variant, stage IVB. The main immunophenotype characteristics were cyclin D1 +, CD5 +, CD10 -, CD23 -, Bcl-6 -/+, and a high (up to 80%) Ki-67 proliferation index...
May 30, 2016: Survey of Ophthalmology
Christopher M Stewart, Lee Teak Tan, David Johnson, Jonathan H Norris
Reconstruction of full thickness, total upper eyelid defects represents a significant challenge in terms of recreating an upper eyelid which has acceptable cosmesis and a degree of dynamic function. Options include bridging, eyelid-sharing techniques (e.g., Cutler-Beard), or nonbridging techniques such as an anterior lamella-based flap combined with a posterior lamella free graft or a "sandwich flap." The success of these techniques depends on the size of the defect, postoperative cosmesis and whether or not the upper eyelid still has a degree of dynamic function to avoid ptosis and exposure keratopathy...
July 2016: Ophthalmic Plastic and Reconstructive Surgery
Adil Belmokhtar, Rajae Daoudi
No abstract text is available yet for this article.
2016: Pan African Medical Journal
Jasdeep S Chahal, Martin Heur, Gloria B Chiu
OBJECTIVES: To investigate the utility of Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) scleral lenses in patients with exposure keratopathy, with outcomes based on changes in visual acuity, visual function, and corneal staining. METHODS: A retrospective interventional case series of patients evaluated and treated from September 2009 through June 2014 at a single multi-specialty institutional practice. Eighteen of 29 patients with exposure keratoconjunctivitis, lagophthalmos, ectropion, or lid retraction, referred to USC Eye Institute after failing conventional therapies completed PROSE scleral lens fitting and were included in the study...
May 11, 2016: Eye & Contact Lens
Selam Yekta Sendul, Burcu Dirim, Mehmet Demir, Zeynep Acar, Atilla Gokce Demir, Ali Olgun, Semra Tiryaki, Cemile Ucgul, Dilek Guven
BACKGROUND: The purpose of this study was to evaluate the results of tarsoaponeurectomy in patients with unsuccessful results after repetitive surgery or who developed post-traumatic blepharoptosis. METHODS: The files of 107 patients (136 eyes) on whom surgery was performed between January 2010 and December 2014 due to blepharoptosis were scanned retrospectively. Among these patients, the files and operational notes of eight patients who underwent surgery through the method of tarsoaponeurectomy were examined in detail...
2016: BMC Ophthalmology
Oludolapo Sherifat Katibi, Feyiyemi Grace Adepoju, Benedict Oluwasesan Olorunsola, Samuel Kolade Ernest, Kehinde Fasasi Monsudi
BACKGROUND: Snake envenomation is a major public health problem of the Savannah regions of West Africa. Ocular manifestations of snakebites are rare with few reports documenting blindness as a complication. OBJECTIVE: To highlight an unusual manifestation of snake bites and its attendant problems. METHODS: A report of scalp haematoma and blindness in a 10 year old child presenting 2 weeks after a snake bite (presumably carpet viper) is a rare manifestation...
September 2015: African Health Sciences
Yuqiu Zhang, Hong Cao, Tong Lin, Lan Gong
The aim of the study was to observe the effect of different artificial tears on healing the drug-induced keratopathy. To this aim, 64 rabbits received topical administration of 0.01% benzalkonium chloride to establish models and were divided into four groups. The control group received ocular saline solution (Saline), while the others were treated with Refresh Plus® (RF), Hycosan® (H) and Systane® Ultra (SU). Surface abnormalities were examined daily using slit-lamp. Fluorescein staining, histopathological and transmission electron microscopic (TEM) examination were performed at day 0, 2 weeks, and 1 and 2 months...
October 2016: Drug and Chemical Toxicology
Alice Y Matoba, Jeff R Peterson, Kirk R Wilhelmus
PURPOSE: To describe dendritiform keratopathy associated with exposure to polyquaternium-1, a common preservative found in contact lens solutions and tear replacement products. DESIGN: Case series. PARTICIPANTS: Sixteen patients who demonstrated dendritiform keratopathy during topical ophthalmic exposure to polyquaternium-1. METHODS: Records were reviewed of all patients diagnosed with dendritiform keratopathy between 1999 and 2014 who had documented exposure to contact lens care disinfecting solutions or artificial tear solutions containing polyquaternium-1...
March 2016: Ophthalmology
Sudarshan Khokhar, Bhagabat Nayak, Bharat Patil, Milind Devidas Changole, Gautam Sinha, Reetika Sharma, Lipika Nayak
A 17-year-old male presented with gradual painless diminution of vision since childhood. Slit lamp examination revealed both eyes having congenital cataract. Right eye lens aspiration was performed but was uneventful, and he prepared for left eye surgery after 7 days. Immediately after giving a peribulbar block, a complete akinesia, tight eyelids, and stony hard eyeball was noted. An abaxial proptosis of 7 mm was noted. Lateral canthotomy and inferior cantholysis were done and proptosis reduced to 5 mm. Bleeding time-clotting time was normal...
2015: International Medical Case Reports Journal
Eric Feinstein, Aisha S Traish, Vinay Aakalu, Iris S Kassem
We describe a rare case of an infant who was born with multiple congenital anomalies, including the absence of eyelids. This patient had many dysmorphic features consistent with a severe phenotype of ablepharon-macrostomia syndrome (AMS) including a fish-like appearance of the mouth, rudimentary ears, absence of body hair, thin skin, absent nipples, abdominal distension, and genital abnormalities. Upon presentation, there was severe exposure keratopathy causing large bilateral sterile ulcers culminating in corneal melting of both eyes...
September 2015: Case Reports in Ophthalmology
Chris Y Wu, Victor M Elner, Alon Kahana
Thyroid eye disease (TED) usually has mild manifestations in pediatric patients, and orbital decompression is rarely necessarily. The authors present the clinical course of 3 pediatric patients age 16 or younger at the time of decompression surgery with severe orbitopathy. Case 1 is a 9-year-old prepubertal Asian-American female with Graves' disease and TED who underwent balanced decompression for compressive optic neuropathy. Case 2 is a 14-year-old Caucasian female with Graves' disease and TED who underwent balanced decompression for compressive optic neuropathy, stretch optic neuropathy, and globe subluxation...
October 30, 2015: Ophthalmic Plastic and Reconstructive Surgery
M Porubanova, A Sharashidze, J Hornova, A Gerinec
Infantile capillary haemangioma (IH) is the most common congenital vascular tumor of childhood and infancy. Although the majority of these lesions regress spontaneously, many of children with IH particularly in the periocular or orbital region need treatment. Ocular indications for treatment include obstruction of the visual axis or high degrees of astigmatism causing amblyopia, exposure keratopathy secondary to proptosis or compressive optic neuropathy. Our purpose was to assess the effectiveness and tolerance of beta-blockers (BB), propranolol and metoprolol, in the treatment of these lesions...
2015: Neoplasma
Shani S Reich, Robert C Null, Peter J Timoney, Jason A Sokol
PURPOSE: To assess current members of the American Society of Ophthalmic Plastic and Reconstructive Surgery (ASOPRS) regarding preference in surgical techniques for orbital decompression in Graves' disease. METHODS: A 10-question web-based, anonymous survey was distributed to oculoplastic surgeons utilizing the ASOPRS listserv. The questions addressed the number of years of experience performing orbital decompression surgery, preferred surgical techniques, and whether orbital decompression was performed in collaboration with an ENT surgeon...
September 30, 2015: Ophthalmic Plastic and Reconstructive Surgery
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