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https://www.readbyqxmd.com/read/28092724/the-pediatric-rome-iv-criteria-what-s-new
#1
Ilan J N Koppen, Samuel Nurko, Miguel Saps, Carlo Di Lorenzo, Marc A Benninga
Functional gastrointestinal disorders (FGIDs) are common in children of all ages and comprise of a wide range of conditions related to the gastrointestinal tract that cannot be attributed to structural or biochemical abnormalities. FGIDs are diagnosed according to the symptom-based Rome criteria. Areas covered: In 2016, the revised pediatric Rome IV criteria were published, these revised criteria are discussed in this review article. For the youngest age group (neonates/toddlers), the criteria for infant colic have undergone the most notable revisions...
January 16, 2017: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28090490/iron-deficiency-anemia-in-infants-and-toddlers
#2
Eun Young Joo, Keun Young Kim, Dong Hyun Kim, Ji-Eun Lee, Soon Ki Kim
BACKGROUND: In Korea, the prevalence of anemia and iron deficiency anemia (IDA) among older infants and young children remains high. To detect IDA early and to reduce its adverse impact, we assessed the characteristics of infants and young children who had IDA or were at risk of developing IDA, or who exhibited characteristics associated with severe anemia. METHODS: Among the 1,782 IDA-affected children aged 6 months to 18 years who visited the hospital, we retrospectively analyzed the medical records and laboratory data of 1,330 IDA-affected children aged 6-23 months who were diagnosed between 1996 and 2013...
December 2016: Blood Research
https://www.readbyqxmd.com/read/28088692/evaluation-of-motor-and-cognitive-development-among-infants-exposed-to-hiv
#3
Kaitiana Martins da Silva, Cristina Dos Santos Cardoso de Sá, Raquel Carvalho
This study of a prospective and cross-sectional nature compared the motor and cognitive development of HIV-exposed and unexposed infants in their first 18months of age. 40 infants exposed to HIV and antiretroviral therapy (Experimental Group - EG) and 40 unexposed infants (Control Group - CG) participated in the study. They were divided into four age groups of 4, 8, 12 and 18months old, with 10 infants from EG and 10 from CG in each group. The infants were evaluated once on motor and cognitive development by the Bayley Scale of Infant and Toddler Development...
January 12, 2017: Early Human Development
https://www.readbyqxmd.com/read/28079770/neurodevelopmental-outcomes-after-assisted-reproductive-technologies
#4
Jacques Balayla, Odile Sheehy, William D Fraser, Jean R Séguin, Jacquetta Trasler, Patricia Monnier, Andrea A MacLeod, Marie-Noëlle Simard, Gina Muckle, Anick Bérard
OBJECTIVE: To compare children's cognitive, motor, and language development at 2 years of age after assisted reproductive technologies (ARTs) relative to natural conception. METHODS: The 3D-Study (2010-2012) is a prospective cohort study, which sought to improve the understanding among perinatal events, obstetric outcomes, and child development. A total of 2,366 pregnant women were recruited, of whom 278 conceived with ART: ovarian stimulation, intrauterine sperm insemination, in vitro fertilization, intracytoplasmic sperm injection, or in vitro maturation...
January 9, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28076664/sensitization-predicts-asthma-development-among-wheezing-toddlers-in-secondary-healthcare
#5
Nienke A Boersma, Ruud W H Meijneke, Johannes C Kelder, Cornelis K van der Ent, Walter A F Balemans
INTRODUCTION: Some wheezing toddlers develop asthma later in childhood. Sensitization is known to predict asthma in birth cohorts. However, its predictive value in secondary healthcare is uncertain. AIM: This study examines the predictive value of sensitization to inhalant allergens among wheezing toddlers in secondary healthcare for the development of asthma at school age (≥6 years). METHODS: Preschool children (1-3 years) who presented with wheezing in secondary healthcare were screened on asthma at school age with the International Study of Asthma and Allergies in Childhood questionnaire...
January 11, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28072957/-a-cross-sectional-survey-on-the-patterns-of-primary-teeth-eruption-in-2-581-children
#6
R X Li, Y Hu
Objective: To investigate the patterns of primary teeth eruption by a cross-sectional survey in 0-40 months old children in Chongqing and to provide normal timetables of tooth eruption that are practical in general physical growth assessment. Method: Data of 2 581 0-40 months old healthy children were collected from January 2014 to January 2016 at Children's Hospital of Chongqing Medical University. General information was recorded by primary child health care doctors, including age, gender, gestation age, birth weight, time and sequence of first primary tooth eruption, number of teeth and age of totally primary teeth emergence...
January 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28068550/toddlers-word-learning-and-transfer-from-electronic-and-print-books
#7
Gabrielle A Strouse, Patricia A Ganea
Transfer from symbolic media to the real world can be difficult for young children. A sample of 73 toddlers aged 17 to 23months were read either an electronic book displayed on a touchscreen device or a traditional print book in which a novel object was paired with a novel label. Toddlers in both conditions learned the label within the context of the book. However, only those who read the traditional format book generalized and transferred the label to other contexts. An older group of 28 toddlers aged 24 to 30months did generalize and transfer from the electronic book...
January 6, 2017: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/28067718/immunogenicity-and-safety-of-a-booster-injection-of-dtap-ipv-hib-pentaxim%C3%A2-administered-concomitantly-with-tetravalent-dengue-vaccine-in-healthy-toddlers-aged-15-to-18-months-in-mexico-a-randomized-trial
#8
Flor Irene Rodriguez Melo, José Juan Renteria Morales, Abiel Homero Mascareñas De Los Santos, Enrique Rivas, Claire Vigne, Fernando Noriega
BACKGROUND: The live, attenuated, tetravalent dengue vaccine (CYD-TDV) is licensed in a number of dengue endemic countries for individuals ≥9 years old. Before integration of any vaccine into childhood vaccination schedules, a lack of immune interference and acceptable safety when co-administered with other recommended vaccines should be demonstrated. METHODS: This randomized, multi-center, Phase III trial was conducted in Mexico. Healthy toddlers (n=732) received a booster dose of a licensed pentavalent combination vaccine (diphtheria, tetanus, acellular pertussis, inactivated polio vaccine, and Haemophilus influenzae type b [DTaP-IPV//Hib]) either concomitantly or sequentially with the second dose of CYD-TDV administered as a 3-dose schedule...
January 6, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28065826/scn2a-p-ala263val-variant-a-phenotype-of-neonatal-seizures-followed-by-paroxysmal-ataxia-in-toddlers
#9
Kathleen Mary Gorman, Mary Dolores King
No abstract text is available yet for this article.
December 8, 2016: Pediatric Neurology
https://www.readbyqxmd.com/read/28065531/corrigendum-to-perceptions-of-food-intake-and-weight-status-among-parents-of-picky-eating-infants-and-toddlers-in-china-a-cross-sectional-study-appetite-108-2017-456-463
#10
Ziyi Li, Klazine van der Horst, Lisa R Edelson-Fries, Kai Yu, Lili You, Yumei Zhang, Gerard Vinyes-Pares, Peiyu Wang, Defu Ma, Xiaoguang Yang, Liqiang Qin, Jiaji Wang
No abstract text is available yet for this article.
March 1, 2017: Appetite
https://www.readbyqxmd.com/read/28064355/population-pharmacokinetic-models-of-lamotrigine-in-different-age-groups-of-chinese-children-with-epilepsy
#11
Zhong-Bin Zhang, Shuang-Min Ji, Ying Han, Li-Li Zang, Ying-Hui Wang, Wei Lu, Li Wang, Ye Wu
PURPOSE: The study aims to establish population pharmacokinetic (PPK) models of lamotrigine (LTG) in different age groups of epileptic children by nonlinear mixed effect modelling(NONMEM), and provide essential tools and theoretical basis for individualised optimal drug dose. METHODS: Cases of 473 epileptic children were divided into infant, toddler and preschool age (≤6 years) (n = 211), school age (6-12 years) (n = 171) and adolescence age (>12 years) (n = 81)...
January 7, 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28063312/concentrations-of-short-and-medium-chain-chlorinated-paraffins-in-indoor-dusts-from-malls-in-china-implications-for-human-exposure
#12
Leimeng Shi, Yuan Gao, Haijun Zhang, Ningbo Geng, Jiazhi Xu, Faqiang Zhan, Yuwen Ni, Xiaohong Hou, Jiping Chen
Levels and distribution of short- and medium-chain chlorinated paraffins (SCCPs and MCCPs) were measured in indoor dusts from malls in China. The concentrations of SCCPs and MCCPs in dustfalls from a building material mall ranged from 6.0 to 361.4 μg g(-1) and from 5.0 to 285.9 μg g(-1), respectively. Much heavier contamination was found in central air conditioner filter (CACF) dusts from a newly opened shopping mall, with SCCP concentrations of 114.7-707.0 μg g(-1) and MCCP concentrations of 89.0-1082...
January 2, 2017: Chemosphere
https://www.readbyqxmd.com/read/28062515/joint-attention-and-brain-functional-connectivity-in-infants-and-toddlers
#13
Adam T Eggebrecht, Jed T Elison, Eric Feczko, Alexandre Todorov, Jason J Wolff, Sridhar Kandala, Chloe M Adams, Abraham Z Snyder, John D Lewis, Annette M Estes, Lonnie Zwaigenbaum, Kelly N Botteron, Robert C McKinstry, John N Constantino, Alan Evans, Heather C Hazlett, Stephen Dager, Sarah J Paterson, Robert T Schultz, Martin A Styner, Guido Gerig, Samir Das, Penelope Kostopoulos, Bradley L Schlaggar, Steven E Petersen, Joseph Piven, John R Pruett
Initiating joint attention (IJA), the behavioral instigation of coordinated focus of 2 people on an object, emerges over the first 2 years of life and supports social-communicative functioning related to the healthy development of aspects of language, empathy, and theory of mind. Deficits in IJA provide strong early indicators for autism spectrum disorder, and therapies targeting joint attention have shown tremendous promise. However, the brain systems underlying IJA in early childhood are poorly understood, due in part to significant methodological challenges in imaging localized brain function that supports social behaviors during the first 2 years of life...
January 6, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28062427/novel-sleep-management-method-in-a-toddler-displaying-fear-and-trauma-the-boss-of-my-sleep-book
#14
Sarah Blunden
Sleep problems in toddlers occur in ∼40% of children and increase the likelihood of postnatal depression. Most sleep training in toddlers requires contact with a trained professional, and requires a parent to ignore their child's cries, causing distress to many children and parents, increasing attrition and leaving families untreated and at risk. This case study reports success in significantly ameliorating sleep reluctance and bedtime fears in a sleep disturbed toddler with a history of trauma. It uses a novel use of bedtime behaviour management with some positive reinforcement techniques, called the Boss of My Sleep book: a non-cry, online (thus readily and cheaply available without a trained professional) sleep intervention...
January 6, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28060048/a-randomized-controlled-trial-to-evaluate-a-potential-hepatitis-b-booster-vaccination-strategy-using-combined-hepatitis-a-and-b-vaccine
#15
Fangjun Li, Yuansheng Hu, Youming Zhou, Lixin Chen, Wei Xia, Yufei Song, Zhengliang Tan, Lidong Gao, Zhong Yang, Gang Zeng, Xing Han
BACKGROUND: Booster doses could play a major role in those no responders or low responders to primary hepatitis B vaccine. Planed time point for hepatitis A vaccination in China provides a good opportunity to carry out hepatitis B booster dose by using combined hepatitis A and B vaccine. METHOD: A randomized, double blinded clinical trial was conducted to compare the immunogenicity and safety of toddlers 18-24 months of age receiving three different vaccination regimens: either two doses of inactivated hepatitis A vaccine (group 1), or one dose inactivated hepatitis A vaccine plus one dose combined hepatitis A and B vaccine (group 2), or two doses of combined hepatitis A and B vaccine (group 3) respectively...
January 3, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28058243/assessment-of-perfluorooctane-sulfonate-and-perfluorooctanoic-acid-exposure-through-fish-consumption-in-italy
#16
Andrea Barbarossa, Teresa Gazzotti, Federica Farabegoli, Francesca R Mancini, Elisa Zironi, Luca Busani, Giampiero Pagliuca
Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are pollutants of anthropic origin with possible side effects on human health. Diet, and in particular fish and seafood, is considered the major intake pathway for humans. The present study investigated the levels of perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) contamination in twenty-five samples of fresh fillet of five widely consumed fish species purchased from large retailers in Italy, to be used for an estimation of the Italian population exposure to these contaminants...
September 20, 2016: Italian Journal of Food Safety
https://www.readbyqxmd.com/read/28042897/early-childhood-predictors-of-severe-youth-violence-in-low-income-male-adolescents
#17
Stephanie L Sitnick, Daniel S Shaw, Chelsea M Weaver, Elizabeth C Shelleby, Daniel E Choe, Julia D Reuben, Mary Gilliam, Emily B Winslow, Lindsay Taraban
Using a cohort of 310 low-income male adolescents living in an urban community and followed prospectively from 18 months through adolescence (ages 15-18 years), the current study examined whether individual, family, and community risk factors from ages 18 to 42 months were associated with adolescents' violent behavior, as indexed by juvenile petitions. Results of multivariate analyses indicated that although family income was the only factor to discriminate those with no arrest record from those with nonviolent arrests, rejecting parenting, child oppositional behavior, emotion regulation, and minority status during the toddler period contributed unique variance in distinguishing male adolescents arrested for violent behavior compared to those never arrested and those arrested for nonviolent behavior...
January 2017: Child Development
https://www.readbyqxmd.com/read/28042661/associations-between-early-maternal-depressive-symptom-trajectories-and-toddlers-felt-security-at-18-months-are-boys-and-girls-at-differential-risk
#18
Marjorie Beeghly, Ty Partridge, Ed Tronick, Maria Muzik, Mahya Rahimian Mashhadi, Jordan L Boeve, Jessica L Irwin
The goal of this study was to evaluate whether there are sex differences in children's vulnerability to caregiving risk, as indexed by trajectories of maternal depressive symptoms assessed from 2 to 18 months' postpartum, and children's rated attachment security in toddlerhood, adjusting for maternal social support and demographic risk. Analyses utilized longitudinal data collected for 182 African American mother-child dyads from economically diverse backgrounds. Participants were recruited at the time of the child's birth and followed to 18 months' postpartum...
January 2017: Infant Mental Health Journal
https://www.readbyqxmd.com/read/28035545/dtap5-hb-ipv-hib-vaccine-vaxelis-%C3%A2-a-review-of-its-use-in-primary-and-booster-vaccination
#19
Yahiya Y Syed
Vaxelis(®) is a fully liquid, ready-to-use, hexavalent vaccine approved in the EU for primary and booster vaccination in infants and toddlers from the age of 6 weeks against diphtheria, tetanus, pertussis, hepatitis B, poliomyelitis, and invasive diseases caused by Haemophilus influenzae type b (Hib). It contains diphtheria and tetanus toxoids, five acellular pertussis antigens, recombinant hepatitis B virus surface antigen produced in the yeast, Saccharomyces cerevisiae, inactivated poliovirus, and the Hib polysaccharide (polyribosylribitol phosphate) conjugated to the outer membrane protein complex of Neisseria meningitidis...
December 29, 2016: Paediatric Drugs
https://www.readbyqxmd.com/read/28030526/long-term-immunogenicity-of-a-single-dose-of-japanese-encephalitis-chimeric-virus-vaccine-in-toddlers-and-booster-response-5-years-after-primary-immunization
#20
Pope Kosalaraksa, Veerachai Watanaveeradej, Chitsanu Pancharoen, Maria Rosario Capeding, Emmanuel Feroldi, Alain Bouckenooghe
BACKGROUND: Japanese encephalitis (JE) is an important mosquito-borne viral disease that is endemic in Asia, Western Pacific countries, and Northern Australia. Although there is no antiviral treatment, vaccination is effective in preventing this disease. METHODS: We followed a cohort of 596 children for 5 years after primary vaccination at 12-18 months of age with JE chimeric virus vaccine (JE-CV; IMOJEV) in a multicenter, phase III trial in Thailand and the Philippines to assess antibody persistence and safety...
December 27, 2016: Pediatric Infectious Disease Journal
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