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https://www.readbyqxmd.com/read/28211597/data-quality-assurance-and-control-in-cognitive-research-lessons-learned-from-the-predict-hd-study
#1
Holly James Westervelt, Rachel A Bernier, Melanie Faust, Mary Gover, H Jeremy Bockholt, Roland Zschiegner, Jeffrey D Long, Jane S Paulsen
We discuss the strategies employed in data quality control and quality assurance for the cognitive core of Neurobiological Predictors of Huntington's Disease (PREDICT-HD), a long-term observational study of over 1,000 participants with prodromal Huntington disease. In particular, we provide details regarding the training and continual evaluation of cognitive examiners, methods for error corrections, and strategies to minimize errors in the data. We present five important lessons learned to help other researchers avoid certain assumptions that could potentially lead to inaccuracies in their cognitive data...
February 17, 2017: International Journal of Methods in Psychiatric Research
https://www.readbyqxmd.com/read/28211151/phenotypic-distribution-models-corroborate-species-distribution-models-a-shift-in-the-role-and-prevalence-of-a-dominant-prairie-grass-in-response-to-climate-change
#2
Adam B Smith, Jacob Alsdurf, Mary Knapp, Sara G Baer, Loretta C Johnson
Phenotypic variation within species can vary widely across environmental gradients but forecasts of species' responses to environmental change often assume species respond homogenously across their ranges. We compared predictions from species and phenotype distribution models under future climate scenarios for Andropogon gerardii, a widely distributed, dominant grass found throughout the central United States. Phenotype data on aboveground biomass, height, leaf width, and chlorophyll content were obtained from 33 populations spanning a ~1000-km gradient that encompassed the majority of the species' environmental range...
February 17, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28210357/a-survey-of-emergency-medicine-residents-use-of-educational-podcasts
#3
Jeff Riddell, Anand Swaminathan, Monica Lee, Abdiwahab Mohamed, Rob Rogers, Salim R Rezaie
INTRODUCTION: Emergency medicine (EM) educational podcasts have become increasingly popular. Residents spend a greater percentage of their time listening to podcasts than they do using other educational materials. Despite this popularity, research into podcasting in the EM context is sparse. We aimed to determine EM residents' consumption habits, optimal podcast preferences, and motivation for listening to EM podcasts. METHODS: We created a survey and emailed it to EM residents at all levels of training at 12 residencies across the United States from September 2015 to June 2016...
February 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28208990/swiss-ball-versus-mat-exercises-for-core-activation-of-transverse-abdominis-in-recreational-athletes
#4
Prateek Srivastav, Nirmala Nayak, Sudeep Nair, Lobsang Bhuti Sherpa, Diana Dsouza
INTRODUCTION: Core stability is an essential component for improving athletic performance and injury prevention. Exercises on a Swiss ball and on the mat are two different ways of improving core stability. Comparison of these methods can help physiotherapists incorporate the better method for athletic training and rehabilitation. AIM: To compare swiss ball and mat exercises for core stability of transverse abdominis in recreational athletes. MATERIALS AND METHODS: This pilot randomized control trial was performed on a total of 25 recreational athletes...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28207671/a-silver-medal-winner-at-the-13th-world-wu-shu-championship-2015-17-months-after-selective-thoracic-fusion-for-adolescent-idiopathic-scoliosis-a-case-report
#5
Chris Yin Wei Chan, Izzuddin Aziz, Fong Wei Chai, Mun Keong Kwan
STUDY DESIGN: Case report. OBJECTIVE: To report the successful rehabilitation and the training progress of an elite high performance martial art exponent after selective thoracic fusion for Adolescent Idiopathic Scoliosis (AIS). SUMMARY OF BACKGROUND DATA: Posterior spinal fusion for AIS will result in loss of spinal flexibility. The process of rehabilitation after posterior spinal fusion for AIS remains controversial and there are few reports of return to elite sports performance after posterior spinal fusion for AIS...
February 15, 2017: Spine
https://www.readbyqxmd.com/read/28207399/motor-unit-potential-jitter-a-new-measure-of-neuromuscular-transmission-instability
#6
Meena AbdelMaseeh, Daniel Stashuk
OBJECTIVE: A new measure of neuromuscular transmission instability, motor unit potential (MUP) jitter, is introduced. MUP jitter can be estimated quickly using motor unit potential trains (MUPTs) extracted from electromyographic (EMG) signals acquired using conventional clinical equipment and needle EMG electrodiagnostic protocols. The primary motivation for developing MUP jitter is to avoid the technical demands associated with estimating jitter using conventional single fibre EMG techniques...
February 9, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28203055/resident-surgeon-efficiency-in-femtosecond-laser-assisted-cataract-surgery
#7
Andrew C Pittner, Brian R Sullivan
PURPOSE: Comparison of resident surgeon performance efficiencies in femtosecond laser-assisted cataract surgery (FLACS) versus conventional phacoemulsification. PATIENTS AND METHODS: A retrospective cohort study was conducted on consecutive patients undergoing phacoemulsification cataract surgery performed by senior ophthalmology residents under the supervision of 1 attending physician during a 9-month period in a large Veterans Affairs medical center. Medical records were reviewed for demographic information, preoperative nucleus grade, femtosecond laser pretreatment, operative procedure times, total operating room times, and surgical complications...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28198354/noise-robust-unsupervised-spike-sorting-based-on-discriminative-subspace-learning-with-outlier-handling
#8
Mohammad Reza Keshtkaran, Zhi Yang
OBJECTIVE: Spike sorting is a fundamental preprocessing step for many neuroscience studies which rely on the analysis of spike trains. Most of the feature extraction and dimensionality reduction techniques that have been used for spike sorting give a projection subspace which is not necessarily the most discriminative one. Therefore, the clusters which appear inherently separable in some discriminative subspace may overlap if projected using conventional feature extraction approaches leading to a poor sorting accuracy especially when the noise level is high...
February 15, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28198152/discovery-of-cdc25a-lead-inhibitors-with-novel-chemotype-by-virtual-screening-application-of-pharmacophore-modeling-based-on-training-set-with-unique-limited-components
#9
Yushu Ge, Qianqian Han, Wenxiu Duan, Jiaqi Zhang, Kai Chen, Jiajia Wan, Yi Liu, Dan Liu
Cdc25 phosphatase has been studied as an attractive target for cancer therapy. Multiple pharmacophore models with unique core features of classic quinone inhibitors and novel inhibitors were used to discover novel lead inhibitor. 21 compounds with qualified physical properties were screened out from Maybridge hitfinderTM database containing 14400 compounds by pharmacophore models. 4 compounds inhibit the Cdc25A activity more than 50% at concentration of 100 μM. Among them, compound KM10389 (N-(2-((furan-2-ylmethyl)thio)ethyl)-2-((4-hydroxy-6-propylpyrimidin-2-yl)thio)acetamide) shows high enzyme inhibition activity with IC₅₀ of 7...
February 14, 2017: ChemMedChem
https://www.readbyqxmd.com/read/28195970/reduction-of-physiological-strain-under-a-hot-and-humid-environment-by-a-hybrid-cooling-vest
#10
Albert P C Chan, Y Yang, Francis K W Wong, Michael C H Yam, Del P Wong, W F Song
Cooling treatment is regarded as one of good practices to provide safe training conditions to athletic trainers in the hot environment. The present study aimed to investigate whether wearing a commercial lightweight and portable hybrid cooling vest that combines air ventilation fans with frozen gel packs was an effective means to reduce participants' body heat strain. In this within-subject repeated measures study, 10 male volunteers participated in two heat-stress trials (one with the cooling vest - COOL condition, and another without - CON condition, in a randomized order) inside a climatic chamber with a controlled ambient temperature 33 °C and relative humidity (RH) 75% on an experimental day...
February 8, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28194734/physical-and-physiological-profiles-of-brazilian-jiu-jitsu-athletes-a-systematic-review
#11
REVIEW
Leonardo Vidal Andreato, Francisco Javier Díaz Lara, Alexandro Andrade, Braulio Henrique Magnani Branco
BACKGROUND: Brazilian jiu-jitsu is a grappling combat sport that has intermittency as its core element; in other words, actions of high, moderate and low intensity are interspersed during matches, requiring a high level of conditioning to support optimal levels of performance for the total match time. The athletes perform from four to six matches during a day of competition, and this number may increase if the open-class competition, which is held parallel to the competition by weight class, is considered...
December 2017: Sports Medicine—Open
https://www.readbyqxmd.com/read/28193553/an-investigation-of-reactivity-effect-due-to-inadvertent-filling-of-the-irradiation-channels-with-water-in-nirr-1-nigeria-research-reactor-1
#12
U Iliyasu, Y V Ibrahim, Sadiq Umar, S A Agbo, Y Jibrin
Investigation of reactivity variation due to flooding of the irradiation channels of Nigeria Research Reactor (NIRR-1) a low power miniature neutron source reactor (MNSR) located at the Centre for Energy Research and Training, Ahmadu Bello University, Zaria Nigeria using the MCNP code for High Enrich Uranium (HEU) and Low Enrich Uranium (LEU) core has been simulated in this present study. In this work, the excess reactivity worth of flooding HEU core for 1 inner, 2 inner, 3 inner, 4 inner and all inner are 0...
February 9, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28193106/improving-end-of-life-care-knowledge-among-senior-baccalaureate-nursing-students
#13
Toni L Glover, Cynthia Garvan, Rose M Nealis, Sandra W Citty, David J Derrico
OBJECTIVE: It is imperative that nurses are proficient and comfortable providing care to patients at the end of life. Recent studies show that nurses' knowledge of end-of-life care is less than optimal. Effective, evidence-based methods to infuse palliative and end-of-life care education into the undergraduate nursing curriculum are needed. METHODS: A descriptive pre- and postassessment evaluating senior nursing students' acquisition of knowledge on end-of-life care after attending the End-of-Life Nursing Education Consortium (ELNEC) core course was conducted...
January 1, 2017: American Journal of Hospice & Palliative Care
https://www.readbyqxmd.com/read/28184954/-learning-how-to-learn-for-specialist-further-education
#14
G Breuer, B Lütcke, M St Pierre, S Hüttl
The world of medicine is becoming from year to year more complex. This necessitates efficient learning processes, which incorporate the principles of adult education but with unchanged periods of further education. The subject matter must be processed, organized, visualized, networked and comprehended. The learning process should be voluntary and self-driven with the aim of learning the profession and becoming an expert in a specialist field. Learning is an individual process. Despite this, the constantly cited learning styles are nowadays more controversial...
February 2017: Der Anaesthesist
https://www.readbyqxmd.com/read/28184318/training-in-quality-improvement-for-the-next-generation-of-psychiatrists
#15
Elizabeth Ewins, Rob Macpherson, Geoff van der Linden, Stephen Arnott
Quality improvement (QI) projects have been shown to positively influence patient care. They provide opportunities for trainees to present and publish their work locally and nationally, and to gain valuable leadership and management experience. We describe a pilot project to engage in QI trainees across a National Health Service trust and a school of psychiatry. After the first year of this programme over half of psychiatry trainees in the school (58% of core trainees and 47% of advanced trainees) are participating in 28 individual QI projects and QI project methodology is to become embedded in the core psychiatry training course...
February 2017: BJPsych Bulletin
https://www.readbyqxmd.com/read/28183810/systematic-review-of-the-effective-components-of-psychosocial-interventions-delivered-by-care-home-staff-to-people-with-dementia
#16
Penny Rapaport, Gill Livingston, Joanna Murray, Aasiya Mulla, Claudia Cooper
OBJECTIVES: This review aims to understand what elements of psychosocial interventions are associated with improved outcomes for people with dementia to inform implementation in care homes. DESIGN: A systematic review of qualitative and quantitative intervention studies was undertaken. ELIGIBILITY CRITERIA FOR INCLUDED STUDIES: We included primary research studies evaluating psychosocial interventions that trained care home staff to deliver a specific intervention or that sought to change how staff delivered care to residents with dementia and reported staff and resident qualitative or quantitative outcomes...
February 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28181968/service-learning-in-public-health-exploring-the-benefit-to-host-agencies-in-cdc-s-public-health-associate-program
#17
Corinne J Wigington, Robyn K Sobelson, Heather L Duncan, Andrea C Young
The "learn by doing" approach to training is common in the public health field and is a core component of service-learning programs. Trainee satisfaction, learning, and application of learning have been studied. What is less understood is the perspective of the agencies that host trainees. This study aimed to identify whether and how the Centers for Disease Control and Prevention's Public Health Associate Program (PHAP) adds value to the agencies that host trainees during 2-year field assignments. An exploratory, qualitative study design consisting of 9 semistructured telephone interviews with PHAP host agency supervisors was used...
February 8, 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/28181684/exercise-based-cardiac-rehabilitation-for-adults-with-atrial-fibrillation
#18
REVIEW
Signe S Risom, Ann-Dorthe Zwisler, Pernille P Johansen, Kirstine L Sibilitz, Jane Lindschou, Christian Gluud, Rod S Taylor, Jesper H Svendsen, Selina K Berg
BACKGROUND: Exercise-based cardiac rehabilitation may benefit adults with atrial fibrillation or those who had been treated for atrial fibrillation. Atrial fibrillation is caused by multiple micro re-entry circuits within the atrial tissue, which result in chaotic rapid activity in the atria. OBJECTIVES: To assess the benefits and harms of exercise-based rehabilitation programmes, alone or with another intervention, compared with no-exercise training controls in adults who currently have AF, or have been treated for AF...
February 9, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28181348/can-algorithmically-assessed-mri-features-predict-which-patients-with-a-preoperative-diagnosis-of-ductal-carcinoma-in-situ-are-upstaged-to-invasive-breast-cancer
#19
Michael R Harowicz, Ashirbani Saha, Lars J Grimm, P Kelly Marcom, Jeffrey R Marks, E Shelley Hwang, Maciej A Mazurowski
PURPOSE: To assess the ability of algorithmically assessed magnetic resonance imaging (MRI) features to predict the likelihood of upstaging to invasive cancer in newly diagnosed ductal carcinoma in situ (DCIS). MATERIALS AND METHODS: We identified 131 patients at our institution from 2000-2014 with a core needle biopsy-confirmed diagnosis of pure DCIS, a 1.5 or 3T preoperative bilateral breast MRI with nonfat-saturated T1 -weighted MRI sequences, no preoperative therapy before breast MRI, and no prior history of breast cancer...
February 9, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28180130/empowering-education-a-new-model-for-in-service-training-of-nursing-staff
#20
Mahmud Chaghari, Mohsen Saffari, Abbas Ebadi, Ahmad Ameryoun
INTRODUCTION: In-service training of nurses plays an indispensable role in improving the quality of inpatient care. Need to enhance the effectiveness of in-service training of nurses is an inevitable requirement. This study attempted to design a new optimal model for in-service training of nurses. METHODS: This qualitative study was conducted in two stages during 2015-2016. In the first stage, the Grounded Theory was adopted to explore the process of training 35 participating nurses...
January 2017: Journal of Advances in Medical Education & Professionalism
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