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https://www.readbyqxmd.com/read/28325002/radiomic-analysis-of-multi-contrast-brain-mri-for-the-prediction-of-survival-in-patients-with-glioblastoma-multiforme
#1
Ahmad Chaddad, Christian Desrosiers, Matthew Toews
Image texture features are effective at characterizing the microstructure of cancerous tissues. This paper proposes predicting the survival times of glioblastoma multiforme (GBM) patients using texture features extracted in multi-contrast brain MRI images. Texture features are derived locally from contrast enhancement, necrosis and edema regions in T1-weighted post-contrast and fluid-attenuated inversion-recovery (FLAIR) MRIs, based on the gray-level co-occurrence matrix representation. A statistical analysis based on the Kaplan-Meier method and log-rank test is used to identify the texture features related with the overall survival of GBM patients...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324776/microstructural-evolution-of-ti6al4v-in-ultrasonically-assisted-cutting-numerical-modelling-and-experimental-analysis
#2
Wei Bai, Ronglei Sun, Jürgen Leopold, Vadim V Silberschmidt
This paper aims to elucidate the effect of ultrasonically assisted cutting (UAC) on microstructure in a machined surface and a chip of Ti6Al4V alloy. To investigate microstructural evolution, a FE-based cutting model with an enhanced material formulation and temperature dependent material properties was developed. A Johnson-Mehl-Avrami-Kolmogorov (JMAK) model for the Ti6Al4V alloy was employed to simulate dynamic recrystallization and predict a resultant grain size. Due to a specific thermomechanical load in UAC, the distributions of strains, strain rates and temperatures in a workpiece in the machining process were investigated...
March 9, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28324775/investigation-of-the-ultrasonic-attenuation-in-anisotropic-weld-materials-with-finite-element-modeling-and-grain-scale-material-description
#3
P E Lhuillier, B Chassignole, M Oudaa, S O Kerhervé, F Rupin, T Fouquet
A finite element modeling approach of ultrasonic propagation combined with a description of the microstructure at the scale of the grains has been implemented. The simulations seek to determine the contribution of scattering to the ultrasonic attenuation in polycrystalline materials. The approach is applied to anisotropic microstructures exhibiting both elongated grains and transversely isotropic crystallographic texture which can be found in multipass welds. The ultrasonic propagation is computed with the 2D finite element code ATHENA 2D...
March 8, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28324116/thick-prelaminar-tissue-decreases-lamina-cribrosa-visibility
#4
Katie A Lucy, Bo Wang, Joel S Schuman, Richard A Bilonick, Yun Ling, Larry Kagemann, Ian A Sigal, Ireneusz Grulkowski, Jonathan J Liu, James G Fujimoto, Hiroshi Ishikawa, Gadi Wollstein
Purpose: Evaluation of the effect of prelaminar tissue thickness on visualization of the lamina cribrosa (LC) using optical coherence tomography (OCT). Methods: The optic nerve head (ONH) region was scanned using OCT. The quality of visible LC microstructure was assessed subjectively using a grading system and objectively by analyzing the signal intensity of each scan's superpixel components. Manual delineations were made separately and in 3-dimensions quantifying prelaminar tissue thickness, analyzable regions of LC microstructure, and regions with a visible anterior LC (ALC) boundary...
March 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28319652/effect-of-freezing-rate-and-microwave-thawing-on-texture-and-microstructural-properties-of-potato-solanum-tuberosum
#5
David M Phinney, John C Frelka, Anita Wickramasinghe, Dennis R Heldman
Food freezing is a preservation process that works by lowering temperature while simultaneously decreasing water activity. It is accepted that although freezing preserves foods, it generally has a negative effect on textural quality. This research investigated the texture response of potatoes (Solanum tuberosum) as a function of time to freeze (defined as the time for the center temperature to reach -20 °C) and thawing process. Potatoes slices (6 mm) were blanched then frozen in an ethanol/carbon dioxide bath, a pilot scale high velocity air freezer (HVAF) and a still air freezer to achieve various times to freeze...
March 20, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28319334/biofunctionalized-plants-as-diverse-biomaterials-for-human-cell-culture
#6
Gianluca Fontana, Joshua Gershlak, Michal Adamski, Jae-Sung Lee, Shion Matsumoto, Hau D Le, Bernard Binder, John Wirth, Glenn Gaudette, William L Murphy
The commercial success of tissue engineering products requires efficacy, cost effectiveness, and the possibility of scaleup. Advances in tissue engineering require increased sophistication in the design of biomaterials, often challenging the current manufacturing techniques. Interestingly, several of the properties that are desirable for biomaterial design are embodied in the structure and function of plants. This study demonstrates that decellularized plant tissues can be used as adaptable scaffolds for culture of human cells...
March 20, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28319274/intraoperative-optical-coherence-tomography-for-soft-tissue-sarcoma-differentiation-and-margin-identification
#7
Kelly J Mesa, Laura E Selmic, Paritosh Pande, Guillermo L Monroy, Jennifer Reagan, Jonathan Samuelson, Elizabeth Driskell, Joanne Li, Marina Marjanovic, Eric J Chaney, Stephen A Boppart
BACKGROUND AND OBJECTIVE: Sarcomas are rare but highly aggressive tumors, and local recurrence after surgical excision can occur in up to 50% cases. Therefore, there is a strong clinical need for accurate tissue differentiation and margin assessment to reduce incomplete resection and local recurrence. The purpose of this study was to investigate the use of optical coherence tomography (OCT) and a novel image texture-based processing algorithm to differentiate sarcoma from muscle and adipose tissue...
March 20, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28319259/label-free-identification-of-the-microstructure-of-rat-spinal-cords-based-on-nonlinear-optical-microscopy
#8
C X Liao, Z Y Wang, Y Zhou, L Q Zhou, X Q Zhu, W G Liu, J X Chen
The spinal cord is a vital link between the brain and the body and mainly comprises neurons, glial cells and nerve fibres. In this work, nonlinear optical (NLO) microscopy based on intrinsic tissue properties was employed to label-freely analyze the cells and matrix in spinal cords at a molecular level. The high-resolution and high-contrast NLO images of unstained spinal cords demonstrate that NLO microscopy has the ability to show the microstructure of white and grey matter including ventral horn, intermediate area, dorsal horns, ventral column, lateral column and dorsal column...
March 20, 2017: Journal of Microscopy
https://www.readbyqxmd.com/read/28318507/usefulness-of-diffusion-tensor-mri-in-the-diagnosis-of-parkinson-variant-of-multiple-system-atrophy-and-parkinson-s-disease-a-valuable-tool-to-differentiate-between-them
#9
B Chen, G Fan, W Sun, X Shang, S Shi, S Wang, G Lv, C Wu
AIM: To evaluate the differences between patients with Parkinson's disease (PD) and Parkinson variant of multiple system atrophy (MSAp) at fractional anisotropy (FA) in the white matter when using the tract-based spatial statistics (TBSS) algorithm to provide objective markers for a differential diagnosis. MATERIALS AND METHODS: Diffusion-tensor imaging (DTI) data were acquired from 18 PD patients, 20 MSAp patients, and 24 healthy controls using a GE 3 T Signa HDx magnetic resonance imaging (MRI) system...
March 16, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28318460/the-effects-of-the-addition-of-dy-nb-and-ga-on-microstructure-and-magnetic-properties-of-nd2fe14b-%C3%AE-fe-nanocomposite-permanent-magnetic-alloys
#10
Kezhi Ren, Xiaohua Tan, Heyun Li, Hui Xu, Ke Han
We study the effects of Dy, Nb, and Ga additions on the microstructure and magnetic properties of Nd2Fe14B/α-Fe nanocomposites. Dy, Nb, and Ga additions inhibit the growth of the soft magnetic α-Fe phase. Dy and Nb additions are able to refine the microstructure, whereas Ga addition plays only a minor role in prohibiting crystal growth. The magnetic properties are sensitive to Dy, Nb, and Ga additions. The Dy-containing alloy enhances the intrinsic coercivity of 872 kA/m because Dy partially replaces Nd, forming (Nd, Dy)2Fe14B...
March 20, 2017: Microscopy and Microanalysis
https://www.readbyqxmd.com/read/28318000/in-situ-observation-of-self-assembly-of-sugars-and-surfactants-from-nanometres-to-microns
#11
Samia Ouhajji, Jasper Landman, Sylvain Prévost, Lingxiang Jiang, Albert P Philipse, Andrei V Petukhov
The hierarchical self-assembly of sugar and surfactant molecules into hollow tubular microstructures was characterized in situ with high resolution small-angle X-ray scattering spanning more than three orders of magnitude of spatial scales. Scattering profiles reveal that aqueous host-guest inclusion complexes self-assemble into multiple equally spaced curved bilayers forming a collection of concentric hollow cylinders. Scattering data can be described by a simple theoretical model of the microtubes. The interlamellar distance was found to be surprisingly large...
March 20, 2017: Soft Matter
https://www.readbyqxmd.com/read/28317904/robust-and-elastic-lunar-and-martian-structures-from-3d-printed-regolith-inks
#12
Adam E Jakus, Katie D Koube, Nicholas R Geisendorfer, Ramille N Shah
Here, we present a comprehensive approach for creating robust, elastic, designer Lunar and Martian regolith simulant (LRS and MRS, respectively) architectures using ambient condition, extrusion-based 3D-printing of regolith simulant inks. The LRS and MRS powders are characterized by distinct, highly inhomogeneous morphologies and sizes, where LRS powder particles are highly irregular and jagged and MRS powder particles are rough, but primarily rounded. The inks are synthesized via simple mixing of evaporant, surfactant, and plasticizer solvents, polylactic-co-glycolic acid (30% by solids volume), and regolith simulant powders (70% by solids volume)...
March 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28317746/effect-of-vaccinium-bracteatum-thunb-leaf-pigment-on-the-thermal-pasting-and-textural-properties-and-microstructure-characterization-of-rice-starch
#13
Yuan Xu, Mingcong Fan, Sumei Zhou, Li Wang, Haifeng Qian, Hui Zhang, Xiguang Qi
In this study, the thermal, pasting and gel textural properties of japonica rice starch (JRS) and glutinous rice starch (GRS) fortified with Vaccinium bracteatum Thunb. leaf pigment (VBTLP) were investigated. The results showed that VBTLP facilitated the gelatinization of JRS and GRS with earlier onsets of onset temperature (To), peak temperature (Tp), conclusion temperature (Tc), and lower values of gelatinization enthalpy (ΔHg), and retrogradation enthalpy (ΔHr), as the VBTLP level increased. For JRS, VBTLP increased the peak viscosity and breakdown, reduced the final viscosity and setback, but for GRS it increased the peak viscosity, final viscosity, breakdown and setback...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28317277/nasicon-bi2o3-composite-electrolyte-for-all-solid-state-lithium-batteries-low-temperature-fabrication-and-conductivity-enhancement
#14
Sang-Don Lee, Kyu-Nam Jung, Hyeongil Kim, Hyun-Seop Shin, Seung-Wan Song, Min-Sik Park, Jong-Won Lee
All-solid-state lithium batteries offer notable advantages over conventional Li-ion batteries with liquid electrolytes in terms of energy density, stability, and safety. To realize this technology, it is critical to develop highly reliable solid-state inorganic electrolytes with high ionic conductivities and acceptable processability. Li1+xAlxTi2-x(PO4)3 (LATP) with a NASICON (Na superionic conductor)-like structure is regarded as a potential solid electrolyte, owing to its high "bulk" conductivity (~10-3 S cm-1) and excellent stability against air and moisture...
March 20, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28317261/diffusion-relaxation-correlation-spectroscopic-imaging-a-multidimensional-approach-for-probing-microstructure
#15
Daeun Kim, Eamon K Doyle, Jessica L Wisnowski, Joong Hee Kim, Justin P Haldar
PURPOSE: To propose and evaluate a novel multidimensional approach for imaging subvoxel tissue compartments called Diffusion-Relaxation Correlation Spectroscopic Imaging. THEORY AND METHODS: Multiexponential modeling of MR diffusion or relaxation data is commonly used to infer the many different microscopic tissue compartments that contribute signal to macroscopic MR imaging voxels. However, multiexponential estimation is known to be difficult and ill-posed. Observing that this ill-posedness is theoretically reduced in higher dimensions, diffusion-relaxation correlation spectroscopic imaging uses a novel multidimensional imaging experiment that jointly encodes diffusion and relaxation information, and then uses a novel constrained reconstruction technique to generate a multidimensional diffusion-relaxation correlation spectrum for every voxel...
March 19, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28315984/thermomechanical-method-for-cement-extraction-in-revision-arthroplasty
#16
M Ghanem, A Koenig, F Dehn, C-E Heyde, C Josten
BACKGROUND: In joint revision surgery, bone cement extraction remains a major challenge which even today has not seen a satisfactory solution yet. We studied in an experimental setting the impact of heat sources on the mechanical properties and microstructure of bone cement and determined the glass transition temperature (T G) of bone cement. As a result, it would be possible to establish a thermomechanical method which makes use of the structural and material-specific property changes inherent in bone cement at elevated temperatures...
March 18, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28315820/evaluating-differential-nuclear-dna-yield-rates-and-osteocyte-numbers-among-human-bone-tissue-types-a-synchrotron-radiation-micro-ct-approach
#17
Janna M Andronowski, Amy Z Mundorff, Isaac V Pratt, Jon M Davoren, David M L Cooper
Molecular human identification has conventionally focused on DNA sampling from dense, weight-bearing cortical bone tissue, typically from femora or tibiae. A comparison of skeletal elements from three contemporary individuals demonstrated that elements with high quantities of cancellous bone yielded nuclear DNA at the highest rates, suggesting that preferentially sampling cortical bone may be suboptimal (Mundorff & Davoren, 2014). Despite these findings, the reason for the differential DNA yields between cortical and cancellous bone tissues remains unknown...
March 6, 2017: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/28315601/quantitative-characterization-of-enzyme-adsorption-and-hydrolytic-performance-for-ultrafine-grinding-pretreated-corn-stover
#18
Haiyan Zhang, Longjian Chen, Junbao Li, Minsheng Lu, Lujia Han
Quantitative analysis of enzyme adsorption and hydrolysis were performed for sieve-based grinding corn stover (SGCS) and ultrafine grinding corn stover (UGCS)(1) with different enzyme consumptions. The UGCS presented significantly higher enzyme adsorption quantity (5.15mg/g for UGCS, 1.33mg/g for SGCS), higher glucose yield (49.75% for UGCS, 28.75% for SGCS) under 20FPU/g and higher binding enzyme proportion (41.32% for UGCS, 10.64% for SGCS under 5FPU/g) which can be attributed to the more accessible microstructure properties...
March 6, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28315460/classification-and-characterization-of-periventricular-and-deep-white-matter-hyperintensities-on-mri-a-study-in-older-adults
#19
REVIEW
Ludovica Griffanti, Mark Jenkinson, Sana Suri, X X, Abda Mahmood, Nicola Filippini, Claire E Sexton, Anya Topiwala, Charlotte Allan, Mika Kivimäki, Archana Singh-Manoux, Klaus P Ebmeier, Clare E Mackay, Giovanna Zamboni
White matter hyperintensities (WMH) are frequently divided into periventricular (PWMH) and deep (DWMH), and the two classes have been associated with different cognitive, microstructural, and clinical correlates. However, although this distinction is widely used in visual ratings scales, how to best anatomically define the two classes is still disputed. In fact, the methods used to define PWMH and DWMH vary significantly between studies, making results difficult to compare. The purpose of this study was twofold: first, to compare four current criteria used to define PWMH and DWMH in a cohort of healthy older adults (mean age: 69...
March 14, 2017: NeuroImage
https://www.readbyqxmd.com/read/28314242/quercitrin-attenuates-osteoporosis-in-ovariectomized-rats-by-regulating-mitogen-activated-protein-kinase-mapk-signaling-pathways
#20
Li-Zhi Xing, Huai-Jun Ni, Yu-Ling Wang
MAPK signaling pathways are crucial in regulating osteogenesis, a genetic disorder affecting the bones. Quercitrin, a type of flavonoid, is widely distributed in nature and involved in many pharmacological activities. But its osteoprotective functions and mechanism in osteoporosis are far from being understood clearly. In this paper, the MAPK upregulation was observed in the ovariectomy-induced bone loss. Quercitrin was found to downregulate MAPK signaling pathways and prevent the ovariectomy-induced deterioration of bone mineral density (BMD), trabecular microstructure, and bone mechanical characteristics...
March 13, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
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