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Infections chronic kidney disease

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https://www.readbyqxmd.com/read/28912532/chronic-kidney-disease-is-associated-with-poorer-in-hospital-outcomes-in-patients-hospitalized-with-infections-electronic-record-analysis-from-china
#1
Guobin Su, Hong Xu, Gaetano Marrone, Bengt Lindholm, Zehuai Wen, Xusheng Liu, Juan-Jesus Carrero, Cecilia Stålsby Lundborg
Predominantly based on studies from high-income countries, reduced estimated glomerular filtration rate (eGFR) has been associated with increased risk of infections and infection-related hospitalizations (IRHs). We here explore in-hospital outcomes of IRHs in patients with different kidney function. A total of 6,283 adults, not on renal replacement therapy, with a discharge diagnosis of infection, and with an eGFR 1-12 months before index hospitalization, were included from four hospitals in China. We compared in-hospital outcomes (death, intensive care unit (ICU) admission, length of hospital stay (LOHS) and medical expenses), between patients with and without chronic kidney disease (CKD, defined as eGFR ≤ 60 ml/min per 1...
September 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28910789/end-stage-renal-disease-inflammation-and-cardiovascular-outcomes
#2
Lu Dai, Edyta Golembiewska, Bengt Lindholm, Peter Stenvinkel
Despite marked improvements in renal replacement therapy during the last 30 years, the age-adjusted mortality rate in end-stage renal disease (ESRD) patients is still unacceptably high and comparable to that of many malignancies. Cardiovascular disease (CVD) remains the major cause of morbidity and mortality in ESRD patients. However, traditional risk factors can only partially explain the high premature cardiovascular burden in this population. Nontraditional risk factors, including persistent low-grade inflammation, are critical in the pathogenesis of atherosclerosis, vascular calcification, and other causes of CVD and may also contribute to protein-energy wasting and other complications in chronic kidney disease (CKD) patients...
2017: Contributions to Nephrology
https://www.readbyqxmd.com/read/28906351/prevalence-evolution-and-related-risk-factors-of-kidney-disease-among-spanish-hiv-infected-individuals
#3
Javier Juega-Mariño, Anna Bonjoch, Nuria Pérez-Alvarez, Eugenia Negredo, Beatriu Bayes, Josep Bonet, Buenaventura Clotet, Ramon Romero
Prevalence of kidney disease (KD) is increasing among human immunodeficiency virus (HIV)-infected population. Different factors have been related, varying on different published series.The objectives were to study prevalence of KD in those patients, its evolution, and associated risk factors.An observational cohort study of 1596 HIV-positive patients with cross-sectional data collection in 2008 and 2010 was conducted. We obtained clinical and laboratory markers, and registered previous or current treatment with tenofovir (TDF) and indinavir (IDV)...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28905133/rabbit-risk-score-and-icu-admission-due-to-infection-in-patients-with-rheumatoid-arthritis
#4
Herwig Pieringer, Rainer Hintenberger, Erich Pohanka, Clemens Steinwender, Jens Meier, Franz Gruber, Lorenz Auer-Hackenberg
Rheumatoid arthritis (RA) patients are at increased risk of infection. Aim of the present study was to investigate whether RA patients admitted to an intensive care unit (ICU) due to infection have higher Rheumatoid Arthritis Observation of Biologic Therapy (RABBIT) risk scores compared to control RA patients. Seventy-four RA patients (32.4% male) admitted to an ICU due to infection (from January 2002 to December 2013) and 74 frequency-matched control RA patients (16.2% male) were included in this cross-sectional study...
September 14, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28904934/comparison-of-complications-of-arteriovenous-fistula-with-permanent-catheter-in-hemodialysis-patients-a-six-month-follow-up
#5
Ali Momeni, Saeed Mardani, Maryam Kabiri, Masoud Amiri
BACKGROUND: Arteriovenous fistula (AVF), permanent catheter (PC), and vascular graft are three vascular access types used for hemodialysis procedure. Due to insufficient reliable information on the comparison between AVF and PC, this study was conducted to compare AVF and PC regarding dialysis adequacy. MATERIALS AND METHODS: This prospective study was carried out from March, 2013 to September, 2013. In this study, 76 hemodialysis patients were enrolled and assigned to two unequal groups of AVF and PC...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28904744/clinical-and-surgical-characteristics-of-infected-diabetic-foot-ulcers-in-a-tertiary-hospital-of-mexico
#6
Estrella Cervantes-García, Paz María Salazar-Schettino
Background: The objective of this study was to determine the clinical and surgical characteristics of diabetic foot ulcers in a tertiary level hospital in Mexico. Methods: We performed a longitudinal, descriptive study from July, 2012 to August, 2015 on a sample composed of 100 patients with type 2 diabetes mellitus and infected diabetic foot ulcers. We analyzed socio-demographic variables, comorbidities, characteristics of ulcers, and the applied treatment. Results: We found that the most affected areas were the forefoot (48%) and the plantar region (55%) of the foot...
2017: Diabetic Foot & Ankle
https://www.readbyqxmd.com/read/28904436/strongyloid-hyperinfection-in-a-patient-with-immunocompromised-chronic-kidney-disease
#7
S Hedau, V P Reddy, S D Mondhe, J V Devana
Strongyloid hyperinfection is seen in immunocompromised individuals with underlying lung disease. The use of immunosuppressive drugs is an important risk factor. We report a case of IgA nephropathy with crescent, started on glucocorticoid and mycophenolate mofetil. He presented with bilateral lung opacities with breathlessness. As the breathlessness was not improving, despite adequate ultrafiltration, bronchoscopy was done. Bronchoalveolar lavage fluid examination showed the presence of strongyloid larvae, which was later demonstrated in stool also...
September 2017: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/28904428/collapsing-glomerulopathy-a-troublemaker-for-the-renal-allograft-lessons-learnt
#8
K V Kanodia, A V Vanikar, L K Nigam, R D Patel, K S Suthar, H V Patel, H L Trivedi
Collapsing glomerulopathy (CG) is a well-recognized distinct morphological pattern of proliferative parenchymal injury leading to rapid graft failure. We conducted a single-center retrospective study to evaluate the prevalence, clinicopathological features, and prognosis of CG in renal transplant recepient. We analyzed 2518 renal allograft biopsies performed from 2007 to 2015 and correlated their clinicopathological features. The prevalence of CG was 0.83% (21 out of 2518) of allograft biopsies with a higher prevalence of 1...
September 2017: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/28903867/detection-accuracy-of-renibacterium-salmoninarum-in-chinook-salmon-oncorhynchus-tshawytscha-walbaum-from-non-lethally-collected-samples-effects-of-exposure-route-and-disease-severity
#9
Carolyn A Richards, Cheryl A Murphy, Travis O Brenden, Thomas P Loch, Mohamed Faisal
Bacterial kidney disease (BKD), caused by Renibacterium salmoninarum, threatens salmonid populations throughout the Northern hemisphere. Many fishery regulatory authorities require ongoing disease monitoring in hatcheries and spawning runs prior to gamete collection to prevent BKD outbreaks and spread. According to diagnostic protocols of the American Fisheries Society-Fish Health Section, monitoring for R. salmoninarum generally consists of lethal sampling of visceral organs from fish. However, non-lethal sampling would be preferable, especially for valuable broodstock or endangered species...
September 15, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28903508/effect-of-paritaprevir-ritonavir-ombitasvir-dasabuvir-and-ledipasvir-sofosbuvir-regimens-on-survival-compared-with-untreated-hepatitis-c-virus-infected-persons-results-from-erchives
#10
Adeel Ajwad Butt, Peng Yan, Tracey G Simon, Abdul-Badi Abou-Samra
Background: Interferon-based regimens are associated with a substantial survival benefit for persons infected with hepatitis C virus (HCV). Survival data with direct-acting antiviral agents are not available. We conducted this study to quantify the effect of paritaprevir/ritonavir, ombitasvir, dasabuvir (PrOD) and ledipasvir/sofosbuvir (LDV/SOF) regimens upon mortality. Methods: In the Electronically Retrieved Cohort of HCV Infected Veterans (ERCHIVES), a well-established national cohort of HCV-infected Veterans, we identified HCV-infected persons initiated on PrOD or LDV/SOF, excluding those with human immunodeficiency virus, hepatitis B surface antigen positivity, hepatocellular carcinoma, or missing HCV RNA or FIB-4 scores...
September 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28902234/monitoring-of-post-vaccination-anti-hbs-titles-vaccine-in-children-and-adolescents-in-the-pre-dialysis-of-chronic-kidney-disease
#11
Nathália Cristina Pereira da Costa, Mônica Ribeiro Canhestro, Cristina Maria Bouissou Morais Soares, Juliana Scudilio Rodrigues
Introduction: Bacterial or viral diseases are one of the major causes of death in patients with chronic kidney disease (CKD). These patients show a quantitative reduction of levels of antibodies over time. Among the infectious diseases that affect CKD patients, stands out hepatitis B (HB). Immunization and control of antibodies levels against the hepatitis B surface antigen (anti-HBs) are ways to prevent the HB infection in this population. Patients with anti-HBs levels ≥10 IU/ml are considered adequate responders, whereas those with anti-HBs levels ≥ 100 IU/ml are considered excellent responders...
August 28, 2017: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/28898114/diagnostic-challenges-of-kidney-diseases-in-hiv-infected-patients
#12
Robin Chazot, Elisabeth Botelho-Nevers, Anne Frésard, Nicolas Maillard, Christophe Mariat, Frédéric Lucht, Amandine Gagneux-Brunon
Chronic kidney disease (CKD) is a prevalent comorbidity in persons living with HIV infection (PLWH) associated with an increase in cardiovascular morbidity and all-cause mortality. Furthermore, early diagnosis of CKD is difficult in PLWH. Areas covered: We reviewed the main diagnostic tools for CKD in PLWH, and discussed their strengths and limits. We performed a literature search on Pubmed to identify reviews and clinical trials dealing with attractive kidney biomarkers of CKD in PLWH, with the following key words: "HIV AND kidney", "HIV AND Kidney biomarkers", "CKD AND Kidney biomarkers"...
September 12, 2017: Expert Review of Anti-infective Therapy
https://www.readbyqxmd.com/read/28890502/close-monitoring-of-egfr-should-be-performed-in-hiv-infected-patients-aged-over-37-years
#13
Chutatip Limkunakul, Palakorn Srinithiwat, Busaraporn Lochinda, Kittisak Sawanyawisuth
Chronic kidney disease (CKD) has been shown to be a poor prognostic factor in HIV patients. This study aimed to find risk factors in HIV-infected patients with early decline renal function or less than 90 ml/min/1.73m(2). The study was retrospective conducted at Chonprathan Hospital, Thailand. The inclusion criteria were HIV-infected adult patients who were treated at the hospital's HIV clinic and whose eGFR levels at the first visit had been evaluated. Eligible patients were categorized by eGFR level at 90 ml/min/1...
September 11, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28888425/prevalence-and-incidence-of-urinary-tract-and-genital-infections-among-patients-with-and-without-type-2-diabetes
#14
Gregory A Nichols, Kimberly G Brodovicz, Teresa M Kimes, Anouk Déruaz-Luyet, Dorothee B Bartels
OBJECTIVE: Epidemiological data on genitourinary infections (GUIs) comparing patients with and without type 2 diabetes (T2DM) is scant. We aimed to estimate the incidence of urinary tract infections (UTIs), genital infections (GIs), or any GUI in total and stratified by history of GUI and sex. RESEARCH DESIGN AND METHODS: We identified 39,295 patients in the Kaiser Permanente Northwest health plan with T2DM and an equal number of age and sex matched patients without diabetes...
August 3, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28885079/a-review-of-renal-disease-in-children-with-hiv-infection
#15
Ankur Kumar Jindal, Karalanglin Tiewsoh, Rakesh Kumar Pilania
Human immunodeficiency virus (HIV) infection continues to be a leading cause of morbidity and mortality. HIV-infected individuals are now surviving for a relatively longer period and this is because of easy accessibility to antiretroviral therapy these days. As a result, chronic disease-related complications are now being recognized more often. Kidney disease in HIV-infected children can vary from glomerular to tubular-interstitial involvement. We searched the database to identify various kidney diseases seen in HIV-infected children...
September 8, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28884961/bartonellosis-in-chronic-kidney-disease-an-unrecognized-and-unsuspected-diagnosis
#16
REVIEW
Fateme Shamekhi Amiri
Systemic cat scratch disease or bartonellosis is a clinical entity caused by Bartonella henselae, which manifests with necrotizing granulomas in visceral organs. The cat flea, Ctenocephalides felis, is the vector responsible for horizontal transmission of the disease from cat to cat, and its bite can also infect humans. In immunocompromised patients including chronic kidney disease and renal transplant recipients, it can cause persistent and disseminated cat scratch disease. The aim of this paper is to perform a systematic review of the studies that have addressed the diagnostic methods of cat scratch disease in chronic kidney disease and renal transplant recipients...
September 8, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28882930/renal-scar-formation-and-kidney-function-following-antibiotic-treated-murine-pyelonephritis
#17
Patrick D Olson, Lisa K McLellan, Alice Liu, Kelleigh L Briden, Kristin M Tiemann, Allyssa L Daugherty, Keith A Hruska, David A Hunstad
We present a new preclinical model to study treatment, resolution, and sequelae of severe ascending pyelonephritis. Urinary tract infection (UTI), primarily caused by uropathogenic Escherichia coli (UPEC), is a common disease in children. Severe pyelonephritis is the primary cause of acquired renal scarring in childhood, which may eventually lead to hypertension and chronic kidney disease in a small but important fraction of patients. Preclinical modeling of UTI utilizes almost exclusively females, which (in most mouse strains) exhibit inherent resistance to severe ascending kidney infection; consequently, no existing preclinical model has assessed the consequences of recovery from pyelonephritis following antibiotic treatment...
September 7, 2017: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/28882641/clinical-factors-influencing-mortality-risk-in-hospital-acquired-sepsis
#18
Cristina López-Mestanza, David Andaluz-Ojeda, Juan Ramón Gómez-López, Jesús F Bermejo Martín
BACKGROUND: Identification of factors that confer an increased risk of mortality in hospital acquired sepsis (HAS) is necessary to help prevent, and improve the outcome of, this condition. AIM: To evaluate the clinical characteristics and factors associated with mortality in patients with HAS. METHODS: Retrospective study of patients with HAS in a major Spanish Hospital from 2011 to 2015. Data from adults receiving any of the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes associated with sepsis were collected...
September 4, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28879600/infections-and-the-kidney-a-tale-from-the-tropics
#19
Nivedita Kamath, Arpana Iyengar
Tropical infections are caused by a variety of bacteria, viruses and parasitic organisms across varying geographical regions and are more often reported in adults than in children. Most of the infections are acute, presenting as a febrile illness with involvement of multiple organ systems, including the kidney. The gamut of renal manifestations extends from asymptomatic urinary abnormalities to acute kidney injury and-albeit rarely-chronic kidney disease. Tropical infections can involve the glomerular, tubulointerstitial and vascular compartments of the kidney...
September 6, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28879483/molecular-characterization-of-acanthamoeba-strains-isolated-from-the-oral-cavity-of-hemodialysis-patients-in-iran
#20
Maryam Niyyati, Zahra Arab-Mazar, Zohreh Lasjerdi, Jacob Lorenzo-Morales, Adel Espotin, Davood Yadegarynia, Latif Gachkar, Sara Rahmati Roodsari
Free-living amoebae (FLA) of the genus Acanthamoeba are opportunistic pathogenic agents able to cause life-threatening infections in immunosuppressed patients. Chronic kidney disease impairs adaptive and innate immunity. Thus, patients with chronic kidney disease are prone to opportunistic infections by potentially pathogenic FLA. Therefore, in the present study, the investigation of Acanthamoeba genotypes isolated from the oral cavity of hemodialysis patients of reference hospitals in Iran was aimed, using both morphology and molecular (sequence-based analysis) tools...
September 6, 2017: Parasitology Research
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