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JAMA diagnostic test interpretation

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September 2014: Clinical Chemistry
Peter Mazzone, Nancy Obuchowski, Tarek Mekhail, Moulay Meziane, Muzaffar Ahmad
Two recent studies of computed tomography (CT) as a screening test for lung cancer have heightened debate about this topic. Although the International Early Lung Cancer Action Program investigators (N Engl J Med 2006; 355:1763-1771) concluded that annual CT screening can detect lung cancer that is curable, Bach et al (JAMA 2007; 297:953-961) concluded that it may not meaningfully reduce the risk of advanced lung cancer or death from lung cancer. We feel that questions remain about the degree of reduction in lung cancer-specific mortality, the potential morbidity caused by screening, the appropriate group to screen, and the cost-effectiveness of screening...
June 2007: Cleveland Clinic Journal of Medicine
M J Alberts, G Hademenos, R E Latchaw, A Jagoda, J R Marler, M R Mayberg, R D Starke, H W Todd, K M Viste, M Girgus, T Shephard, M Emr, P Shwayder, M D Walker
OBJECTIVE: To develop recommendations for the establishment and operation of primary stroke centers as an approach to improve the medical care of patients with stroke. PARTICIPANTS: Members of the Brain Attack Coalition (BAC), a multidisciplinary group of representatives from major professional organizations involved with delivering stroke care. Supplemental input was obtained from other experts involved in acute stroke care. EVIDENCE: A review of literature published from 1966 to March 2000 was performed using MEDLINE...
June 21, 2000: JAMA: the Journal of the American Medical Association
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