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https://www.readbyqxmd.com/read/28938377/long-term-stability-of-keratometry-scheimpflug-derived-true-net-power-and-total-corneal-refractive-power-after-primary-pterygium-excision
#1
Ka Wai Kam, Timothy A Kuan, Michael W Belin, Alvin L Young
PURPOSE: To evaluate long-term changes in mean keratometry, astigmatism, true net power (TNP), and total corneal refractive power (TCRP) of corneas after primary pterygium excision. METHODS: This is a prospective observational series conducted at a tertiary teaching hospital eye center in Hong Kong. A total of 31 eyes of 31 patients with primary pterygium excision were included. Patients with recurrent or double-headed pterygia or a history of corneal scars from previous trauma, infection, or surgery were excluded...
September 21, 2017: Cornea
https://www.readbyqxmd.com/read/28938055/photosynthetic-phenological-variation-may-promote-coexistence-among-co-dominant-tree-species-in-a-madrean-sky-island-mixed-conifer-forest
#2
D L Potts, R L Minor, Z Braun, G A Barron-Gafford
Across much of western North America, forests are predicted to experience a transition from snow- to rain-dominated precipitation regimes due to anthropogenic climate warming. Madrean sky island mixed conifer forests receive a large portion of their precipitation from summertime convective storms and may serve as a lens into the future for snow-dominated forests after prolonged warming. To better understand the linkage between physiological traits, climate variation, and the structure and function of mixed conifer forests, we measured leaf photosynthetic (A) responses to controlled variation in internal CO2 concentration (Ci) to quantify interspecific phenological variation in A/Ci-derived ecophysiological traits among ponderosa pine (Pinus ponderosa Lawson and C...
September 1, 2017: Tree Physiology
https://www.readbyqxmd.com/read/28937685/microrna-26a-and-26b-inhibit-lens-fibrosis-and-cataract-by-negatively-regulating-jagged-1-notch-signaling-pathway
#3
Xiaoyun Chen, Wei Xiao, Weirong Chen, Xialin Liu, Mingxing Wu, Qu Bo, Yan Luo, Shaobi Ye, Yihai Cao, Yizhi Liu
This corrects the article DOI: 10.1038/cdd.2016.152.
September 22, 2017: Cell Death and Differentiation
https://www.readbyqxmd.com/read/28937506/role-of-lens-extraction-and-laser-peripheral-iridotomy-in-treatment-of-glaucoma
#4
Sara Pose-Bazarra, Augusto Azuara-Blanco
PURPOSE OF REVIEW: Lens extraction in people with coexisting cataract and open angle glaucoma is associated with a reduction in intraocular pressure (IOP). In primary angle-closure glaucoma (PACG), lens extraction and laser peripheral iridotomy (LPI) can be used to open the anterior chamber angle, increase the outflow through the trabecular meshwork and reduce the IOP. The present review will summarize the recent available literature regarding the role of both interventions for the treatment of glaucoma...
September 20, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28936986/characterizing-endourologist-learning-curve-during-percutaneous-nephrolithotomy-implications-on-occupational-dose-and-patients
#5
Jacobo Guiu-Souto, Carlos Otero-Martínez, Daniel Pérez-Fentes, Carlos Fernández-Baltar, Juan F Sánchez-García, Camilo García-Freire, Miguel Pombar, Juan Pardo-Montero
In this study we have characterized the learning curve of percutaneous nephrolithotomy procedures over 301 cases for six years. Different surrogate parameters of clinical expertise have been used, such as dose area product, total procedure time, fluoroscopy time and personal equivalent doses. In addition, two different endourologists have been monitored; one of whom was subjected to a specific Radiation Protection training (ICRP 85). Eye lens dose is estimated from thermoluminescent dosimeters. Significant differences are observed between both endourologists, especially in the fluoroscopy time...
September 22, 2017: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/28936763/sequence-specific-1-h-13-c-and-15-n-resonance-assignments-of-a-cataract-related-variant-g57w-of-human-%C3%AE-s-crystallin
#6
Khandekar Jishan Bari, Shrikant Sharma, Kandala V R Chary
γS-crystallin is a major structural component of the human eye lens, which maintains its stability over the lifetime of an organism with negligible turnover. The G57W mutant of human γS-crystallin (abbreviated hereafter as γS-G57W) is associated with dominant congenital cataracts. In order to provide a structural basis for the ability of γS-G57W causing cataract, we have cloned, overexpressed, isolated and purified the protein. The 2D [(15)N-(1)H]-HSQC spectrum recorded with uniformly (13)C/(15)N-labelled γS-G57W was highly dispersed indicating the protein to adopt an ordered conformation...
September 21, 2017: Biomolecular NMR Assignments
https://www.readbyqxmd.com/read/28936057/unusual-case-of-acute-corneal-hydrops-in-mooren-s-ulcer-treated-with-intracameral-injection-of-perfluoropropane
#7
Manisha Acharya, Abhishek Dave, Umang Mathur
A 15-year-old boy was diagnosed with Mooren's ulcer in the right eye at our cornea clinic. On treatment, he developed acute corneal hydrops, and the vision in the right eye dropped to perception of light. The patient was treated with intracameral injection of perfluoropropane (C3F8) gas which resulted in complete resolution of corneal edema. Contact lens fitting yielded a good visual outcome with a best-corrected visual acuity of 20/80. To the best of our knowledge, this is the only case reporting the occurrence of acute corneal hydrops in a child with Mooren's ulcer...
April 2017: Middle East African Journal of Ophthalmology
https://www.readbyqxmd.com/read/28936050/comparative-evaluation-of-corneal-endothelium-in-patients-with-diabetes-undergoing-phacoemulsification
#8
Pramod K Sahu, Gopal K Das, Sumeet Agrawal, Sabitabh Kumar
PURPOSE: The purpose of this study is to determine if phacoemulsification with posterior chamber foldable intraocular lens implantation has a greater impact on the corneal endothelium of type 2 diabetic patients as compared to nondiabetic controls. MATERIALS AND METHODS: This study compared the corneal endothelial status in sixty patients with diabetes with good glycemic control and sixty nondiabetic controls before and after (1 week, 1 month, 2 month, and 3 month) uneventful phacoemulsification...
April 2017: Middle East African Journal of Ophthalmology
https://www.readbyqxmd.com/read/28936015/looking-through-a-different-lens-examining-the-inequality-mortality-association-in-u-s-counties-using-spatial-panel-models
#9
Tse-Chuan Yang, Stephen A Matthews, Kiwoong Park
Two areas still need further examination in the ecological study of inequality and mortality. First, the evidence for the relationship between income inequality and mortality remains inconclusive, particularly when the analytic unit is small (e.g., county in the U.S.). Second, most previous studies are cross-sectional and are unable to address the recent diverging patterns whereby mortality has decreased and income inequality increased. This study aims to contribute to both topic areas by studying the relationship between inequality and mortality via a spatiotemporal approach that simultaneously considers the spatial structure and the temporal trends of inequality and mortality using county panel data between 1990 and 2010 for the conterminous U...
September 2017: Applied Geography
https://www.readbyqxmd.com/read/28935528/choroidal-thickness-and-axial-length-changes-in-myopic-children-treated-with-orthokeratology
#10
Zhouyue Li, Dongmei Cui, Yin Hu, Sichun Ao, Junwen Zeng, Xiao Yang
PURPOSE: To analyze the change in subfoveal choroidal thickness (SFChT) and its relationship with changes in axial length (AL) in myopic children treated with Orthokeratology (Ortho-k). METHODS: Fifty myopic children participated in this study: 29 subjects were treated with Ortho-k lenses and 21 with single vision distance spectacles. The SFChT and ocular biometrics, including AL, were measured at baseline, one month, and six months after lens wear in both groups...
September 18, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28935513/non-invasive-tryptophan-fluorescence-measurements-as-a-novel-method-of-grading-cataract
#11
Jesper Høiberg Erichsen, Aurore Mensah, Line Kessel
Development of non-invasive treatments for cataract calls for a sensitive diagnostic assay. We conducted a study to test whether the ratio of folded tryptophan to non-tryptophan fluorescence emission (F-factor) may be used for grading cataracts in human lenses. The F-factor was measured on aspirated lens material from eyes undergoing femtosecond laser assisted cataract surgery (FLACS) and was compared to a preoperative optical grading of cataract using Scheimpflug imaging. The preoperative optical grading allocated the cataracts to 1 of 4 categories according to the density of the cataract...
September 18, 2017: Experimental Eye Research
https://www.readbyqxmd.com/read/28935373/human-alpha-a-crystallin-missing-n-terminal-domain-poorly-complexes-with-filensin-and-phakinin
#12
Jose M Chaves, Ratna Gupta, Kiran Srivastava, Om Srivastava
The aim of this study was to determine relative importance of N-terminal domain and C-terminal extension of αA-crystallin during their in vitro complex formation with phakinin and filensin (the two lens-specific intermediate filament [IF] proteins). Cloned phakinin, filensin and vimentin were purified under a denaturing conditions by consecutive DEAE-cellulose-, hydroxyapatite- and Sephadex G-75-column chromatographic methods. WTαA-crystallin, αA-NT (N-terminal domain [residue number 1-63])-deleted and αA-CT (C-terminal terminal extension [residue number 140-173]-deleted), were cloned in pET 100 TOPO vector, expressed in BL-21 (DE3) cells using 1% IPTG, and purified using a Ni(2+)-affinity column...
September 18, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28935363/seagrass-ecosystem-trajectory-depends-on-the-relative-timescales-of-resistance-recovery-and-disturbance
#13
Katherine R O'Brien, Michelle Waycott, Paul Maxwell, Gary A Kendrick, James W Udy, Angus J P Ferguson, Kieryn Kilminster, Peter Scanes, Len J McKenzie, Kathryn McMahon, Matthew P Adams, Jimena Samper-Villarreal, Catherine Collier, Mitchell Lyons, Peter J Mumby, Lynda Radke, Marjolijn J A Christianen, William C Dennison
Seagrass ecosystems are inherently dynamic, responding to environmental change across a range of scales. Habitat requirements of seagrass are well defined, but less is known about their ability to resist disturbance. Specific means of recovery after loss are particularly difficult to quantify. Here we assess the resistance and recovery capacity of 12 seagrass genera. We document four classic trajectories of degradation and recovery for seagrass ecosystems, illustrated with examples from around the world. Recovery can be rapid once conditions improve, but seagrass absence at landscape scales may persist for many decades, perpetuated by feedbacks and/or lack of seed or plant propagules to initiate recovery...
September 18, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28934326/the-effect-of-electronic-health-record-software-design-on-resident-documentation-and-compliance-with-evidence-based-medicine
#14
Yasaira Rodriguez Torres, Jordan Huang, Melanie Mihlstin, Mark S Juzych, Heidi Kromrei, Frank S Hwang
This study aimed to determine the role of electronic health record software in resident education by evaluating documentation of 30 elements extracted from the American Academy of Ophthalmology Dry Eye Syndrome Preferred Practice Pattern. The Kresge Eye Institute transitioned to using electronic health record software in June 2013. We evaluated the charts of 331 patients examined in the resident ophthalmology clinic between September 1, 2011, and March 31, 2014, for an initial evaluation for dry eye syndrome...
2017: PloS One
https://www.readbyqxmd.com/read/28933966/mobile-laser-indirect-ophthalmoscope-for-the-induction-of-choroidal-neovascularization-in-a-mouse-model
#15
Dov Weinberger, Elite Bor-Shavit, Tilda Barliya, Mor Dahbash, Opher Kinrot, Dan D Gaton, Yael Nisgav, Tami Livnat
PURPOSE: This study aims to evaluate and standardize the reliability of a mobile laser indirect ophthalmoscope in the induction of choroidal neovascularization (CNV) in a mouse model. MATERIALS & METHODS: A diode laser indirect ophthalmoscope was used to induce CNV in pigmented male C57BL/6J mice. Standardization of spot size and laser intensity was determined using different aspheric lenses with increasing laser intensities applied around the optic disc. Development of CNV was evaluated 1, 5, and 14 days post laser application using fluorescein angiography (FA), histology, and choroidal flat mounts stained for the endothelial marker CD31 and FITC-dextran...
September 21, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28933191/dementia-friendly-initiatives-a-state-of-the-science-review
#16
Catherine A Hebert, Kezia Scales
Background Dementia friendly initiatives share similarities with the age-friendly movement in a focus on active engagement and creating a good quality of life for older adults. Dementia friendly initiatives offer a welcoming optimistic narrative in dementia studies by embracing dignity, empowerment, and autonomy to enable well-being throughout the dementia trajectory. Purpose The purpose of this review is to explore the current science of dementia friendly initiatives, identify gaps, and inform future research...
January 1, 2017: Dementia
https://www.readbyqxmd.com/read/28933042/anterior-chamber-changes-after-implantable-collamer-lens-implantation-in-high-myopia-using-pentacam-a-prospective-study
#17
Mohamed Nagy Elmohamady, Walid Abdelghaffar
INTRODUCTION: The objective of this study was to evaluate the changes of the anterior chamber (AC) of the eye after implantable Collamer lens (ICL) implantation in high myopia by using the Pentacam. METHODS: The prospective study included 34 high myopic patients (34 eyes). All patients were treated with Visian implantable Collamer lens (ICL) (Staar Surgical Co.) implantation. The Pentacam (Oculus) was used for all cases preoperatively and 1, 3 and 6 months postoperatively...
September 20, 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28932387/peak-nasal-inspiratory-flow-as-outcome-for-provocation-studies-in-allergen-exposure-chambers-a-ga-2-len-study
#18
Georg Boelke, Uwe Berger, Karl-Christian Bergmann, Carsten Bindslev-Jensen, Jean Bousquet, Julia Gildemeister, Marek Jutel, Oliver Pfaar, Torsten Sehlinger, Torsten Zuberbier
BACKGROUND: The GA(2)LEN chamber has been developed as a novel mobile allergen exposure chamber (AEC) allowing standardized multicenter trials in allergy. Hitherto, subjective nasal symptom scores have been the most often used outcome parameter, but in standardized modern trials objective parameters are preferred. Despite its practicability, the objective parameter peak nasal inspiratory flow (PNIF) has been rarely used for allergy trials in the setting of allergen exposure chambers. This study aims to evaluate PNIF as an outcome parameter for provocation studies in AECs...
2017: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/28932340/contact-lenses-for-keratoconus-current-practice
#19
Marilita M Moschos, Eirini Nitoda, Panagiotis Georgoudis, Miltos Balidis, Eleftherios Karageorgiadis, Nikos Kozeis
BACKGROUND: Keratoconus is a chronic, bilateral, usuallly asymmetrical, non-inflammatory, ectatic disorder, being characterized by progressive steepening, thinning and apical scarring of the cornea. Initially, the patient is asymptomatic, but the visual acuity gradually decreases, resulting in significant vision loss due to the development of irregular astigmatism, myopia, corneal thinning and scarring. The classic treatment of visual rehabilitation in keratoconus is based on spectacles and contact lenses (CLs)...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28932335/cataract-surgery-in-patients-with-keratoconus-pearls-and-pitfalls
#20
F Aiello, Q J Nasser, C Nucci, R I Angunawela, Z Gatzioufas, V Maurino
BACKGROUND: Keratoconus (KC) is a common ectatic disorder resulting in progressive corneal thinning and irregular astigmatism. It has been observed that patients affected by KC are more likely to develop lens opacities earlier compared to non-keratoconic patients. OBJECTIVE: Intraocular lens (IOL) selection and refractive outcome prediction are among a number of factors that can make cataract surgery in keratoconic patients challenging. Accurate biometry is often difficult to obtain due to unreliable K measurements and lack of dedicated biometric formulae...
2017: Open Ophthalmology Journal
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