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https://www.readbyqxmd.com/read/28820764/severe-case-of-renal-coloboma-syndrome-in-long-term-follow-up
#1
Lise Sels, Werner Dirven, Koenraad Devriendt, Anita Leys
PURPOSE: To characterize the ocular features of a severe case of renal coloboma syndrome in a long-term follow-up. METHODS: Observational case report over a period of 45 years. Examination under anesthesia at the age of 3 months, repeated ophthalmologic examination (age 7, 14, 25, 45 years), fluorescein and indocyanine green angiography, electroretinography, ocular ultrasound, optical coherence tomography, computed tomography scan orbits, and magnetic resonance imaging of the brain...
August 17, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28820753/prevention-of-exposure-keratopathy-in-critically-ill-patients-a-single-center-randomized-pilot-trial-comparing-ocular-lubrication-with-bandage-contact-lenses-and-punctal-plugs
#2
Itai Bendavid, Inbal Avisar, Irena Serov Volach, Amir Sternfeld, Idit Dan Brazis, Lewaa Umar, Yiftach Yassur, Pierre Singer, Jonathan David Cohen
OBJECTIVES: To compare the effectiveness of bandage contact lenses and punctal plugs with ocular lubricants in preventing corneal damage in mechanically ventilated and sedated critically ill patients. DESIGN: Single-center, prospective, randomized, pilot study. SETTING: Sixteen-bed, general ICU at a tertiary academic medical center. PATIENTS: Adults admitted to the ICU and anticipated to require mechanical ventilation and continuous sedation for greater than or equal to 4 days...
August 17, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28820742/spatial-valley-separation-in-strained-graphene-pn-junction
#3
HongYu Tian, Jun Wang
Valleytronics in analogy to spintronics aims to use the electron valley degree of freedom to carry and manipulate information, and one of urgent tasks in this field is to generate valley-polarized electrons. In this work, we propose using the electron focusing effect in a strained graphene pn junction to separate valleys spatially through a beam of valley-unpolarized electrons, since the strain-induced pseudo-gauge potentials are opposite for K and [Formula: see text] valleys and severely affect the trajectories of K and [Formula: see text] electron propagation...
August 18, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28820449/applying-a-consumer-behavior-lens-to-salt-reduction-initiatives
#4
REVIEW
Áine Regan, Monique Potvin Kent, Monique M Raats, Áine McConnon, Patrick Wall, Lise Dubois
Reformulation of food products to reduce salt content has been a central strategy for achieving population level salt reduction. In this paper, we reflect on current reformulation strategies and consider how consumer behavior determines the ultimate success of these strategies. We consider the merits of adopting a 'health by stealth', silent approach to reformulation compared to implementing a communications strategy which draws on labeling initiatives in tandem with reformulation efforts. We end this paper by calling for a multi-actor approach which utilizes co-design, participatory tools to facilitate the involvement of all stakeholders, including, and especially, consumers, in making decisions around how best to achieve population-level salt reduction...
August 18, 2017: Nutrients
https://www.readbyqxmd.com/read/28820227/emergency-management-leadership-in-2030-shaping-the-next-generation-meta-leader
#5
Carol L Cwiak, Ronald Campbell, Matthew G Cassavechia, Chuck Haynes, Lanita A Lloyd, Neil Brockway, George O Navarini, Byron E Piatt, Mary Senger
The complexities, interdependencies, and ambiguity that face next generation emergency management meta-leaders in an ever-evolving global community heighten the expectation and need for competencies that far exceed those common in practice today and necessitate the ability to move seamlessly through the dimensions of meta-leadership (ie, the person, the situation, and connectivity) while utilizing scientific-based evidence, information, resources, processes, and tools. The objective of this effort was to examine the recently developed next generation emergency management competencies through a meta-leadership lens by juxtaposing the competencies and the meta-leadership model...
March 2017: Journal of Emergency Management: JEM
https://www.readbyqxmd.com/read/28820166/commentary-comprehending-haptic-exteriorization-in-intrascleral-haptic-fixation-of-an-intraocular-lens
#6
Priya Narang
No abstract text is available yet for this article.
August 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28820165/extraocular-needle-guided-haptic-insertion-technique-of-scleral-fixation-intraocular-lens-surgeries-x-nit
#7
Prabu Baskaran, Pratyusha Ganne, Sahil Bhandari, Seema Ramakrishnan, Rengaraj Venkatesh, Prashant Gireesh
The most challenging step in sutureless scleral fixation of intraocular lens (SFIOL) is exteriorization of haptics. The conventional handshake technique has a learning curve since it involves intraocular handing over of haptics from one forceps to another. Here, we describe "extraocular needle-guided haptic insertion technique" (X-NIT), a novel technique of exteriorizing haptics that totally eliminates intraocular manipulations. This method involves sequential introduction of two bent 26-gauge needles through the sclera (pars plicata zone) into the eye which are brought out through a sclerocorneal wound...
August 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28820161/ocular-morbidity-patterns-among-children-in-schools-for-the-blind-in-chennai
#8
M Vs Prakash, S Sivakumar, Ashutosh Dayal, A Chitra, Sudharshini Subramaniam
PURPOSE: To identify the morbidity patterns causing blindness in children attending schools for the blind in Chennai and comparing our data with similar studies done previously. METHODS: A cross-sectional prevalence study was carried out in two schools for the blind in Chennai. Blind schools were visited by a team of ophthalmologists and optometrists. Students with best-corrected visual acuity (BCVA) worse than 3/60 in the better eye were included and relevant history was noted...
August 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28820154/preliminary-validation-of-an-optimized-algorithm-for-intraocular-lens-power-calculation-in-keratoconus
#9
Vicente J Camps, David P Piñero, Esteban Caravaca, Dolores De Fez
PURPOSE: This study aimed to evaluate the theoretical influence on intraocular lens power (PIOL) calculation of the use of keratometric approach for corneal power (Pc) calculation in keratoconus and to develop and validate an algorithm preliminarily to minimize this influence. METHODS: Pcwas calculated theoretically with the classical keratometric approach, the Gaussian equation, and the keratometric approach using a variable keratometric index (nkadj) dependent on r1c(Pkadj)...
August 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28820148/optical-models-for-intraocular-lens-planning-in-keratoconus-a-step-in-the-right-direction-and-more-to-do
#10
EDITORIAL
Rohit Shetty, Abhijit Sinha Roy
No abstract text is available yet for this article.
August 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28820021/e-roster-policy-insights-and-implications-of-codifying-nurse-scheduling
#11
Robert G Drake
Following a decade of dissemination, particularly within the British National Health Service, electronic rostering systems were recently endorsed within the Carter Review. However, electronic rostering necessitates the formal codification of the roster process. This research investigates that codification through the lens of the 'Roster Policy', a formal document specifying the rules and procedures used to prepare staff rosters. This study is based upon analysis of 27 publicly available policies, each approved within a 4-year period from January 2010 to July 2014...
August 1, 2017: Health Informatics Journal
https://www.readbyqxmd.com/read/28819785/assessment-of-the-safety-and-efficacy-of-primary-retropupillary-fixation-of-iris-claw-intraocular-lenses-in-children-with-large-lens-subluxations
#12
Anju Rastogi, Apurva Goray, Prolima Thacker, Kamlesh, Babita
PURPOSE: To evaluate whether retropupillary fixation of the iris-claw intraocular lens (IOL) is a safe and effective treatment option in children with large lens subluxations. METHODS: Fourteen eyes of children between the ages of 8-17 years with lens subluxations more than 7 clock hours underwent pars plana lensectomy-vitrectomy with implantation of the iris-claw IOL in the retropupillary position as a primary procedure. The best corrected visual acuity (BCVA), intraocular pressure (IOP), corneal endothelial count (EC) and the lens position using ultrasound biomicroscopy (UBM) were assessed pre- and postoperatively...
August 17, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28819645/3d-imaging-of-optically-cleared-tissue-using-a-simplified-clarity-method-and-on-chip-microscopy
#13
Yibo Zhang, Yoonjung Shin, Kevin Sung, Sam Yang, Harrison Chen, Hongda Wang, Da Teng, Yair Rivenson, Rajan P Kulkarni, Aydogan Ozcan
High-throughput sectioning and optical imaging of tissue samples using traditional immunohistochemical techniques can be costly and inaccessible in resource-limited areas. We demonstrate three-dimensional (3D) imaging and phenotyping in optically transparent tissue using lens-free holographic on-chip microscopy as a low-cost, simple, and high-throughput alternative to conventional approaches. The tissue sample is passively cleared using a simplified CLARITY method and stained using 3,3'-diaminobenzidine to target cells of interest, enabling bright-field optical imaging and 3D sectioning of thick samples...
August 2017: Science Advances
https://www.readbyqxmd.com/read/28818819/quantifying-human-movement-using-the-movn-smartphone-app-validation-and-field-study
#14
Ralph Maddison, Luke Gemming, Javier Monedero, Linda Bolger, Sarahjane Belton, Johann Issartel, Samantha Marsh, Artur Direito, Madeleine Solenhill, Jinfeng Zhao, Daniel John Exeter, Harshvardhan Vathsangam, Jonathan Charles Rawstorn
BACKGROUND: The use of embedded smartphone sensors offers opportunities to measure physical activity (PA) and human movement. Big data-which includes billions of digital traces-offers scientists a new lens to examine PA in fine-grained detail and allows us to track people's geocoded movement patterns to determine their interaction with the environment. OBJECTIVE: The objective of this study was to examine the validity of the Movn smartphone app (Moving Analytics) for collecting PA and human movement data...
August 17, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28818546/glecaprevir-plus-pibrentasvir-for-chronic-hepatitis-c-virus-genotype-1-2-4-5-or-6-infection-in-adults-with-compensated-cirrhosis-expedition-1-a-single-arm-open-label-multicentre-phase-3-trial
#15
Xavier Forns, Samuel S Lee, Joaquin Valdes, Sabela Lens, Reem Ghalib, Humberto Aguilar, Franco Felizarta, Tarek Hassanein, Holger Hinrichsen, Diego Rincon, Rosa Morillas, Stefan Zeuzem, Yves Horsmans, David R Nelson, Yao Yu, Preethi Krishnan, Chih-Wei Lin, Jens J Kort, Federico J Mensa
BACKGROUND: The once-daily, ribavirin-free, pangenotypic, direct-acting antiviral regimen, glecaprevir coformulated with pibrentasvir, has shown high rates of sustained virological response in phase 2 and 3 studies. We aimed to assess the efficacy and safety of 12 weeks of coformulated glecaprevir and pibrentasvir in patients with hepatitis C virus (HCV) infection and compensated cirrhosis. METHODS: We did this single-arm, open-label, multicentre phase 3 study at 40 sites in Belgium, Canada, Germany, South Africa, Spain, and the USA...
August 14, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28818393/the-modulation-of-the-phosphorylation-status-of-nkcc1-in-organ-cultured-bovine-lenses-implications-for-the-regulation-of-fiber-cell-and-overall-lens-volume
#16
Irene Vorontsova, Paul J Donaldson, Zhiying Kong, Chiharu Wickremesinghe, Leo Lam, Julie C Lim
In this study we have used an antibody that specifically detects the phosphorylation status of the Sodium/Potassium/2 Chloride Cotransporter (NKCC1) to study whether the activity of NKCC1 can be regulated in organ cultured bovine lenses. Western blotting was first used to confirm the expression of NKCC1, phosphorylated NKCC1 (NKCC1-P) and the regulatory kinases WNK/SPAK and phosphatases PP1/PP2A in bovine lenses at the protein level. Changes to NKCC1-P status were then assessed by organ culturing bovine lenses in either isotonic, hypertonic or hypotonic solutions in the presence or absence of the NKCC inhibitor, bumetanide, or phosphatase inhibitors okadaic acid and calyculin A...
August 14, 2017: Experimental Eye Research
https://www.readbyqxmd.com/read/28817733/changing-patterns-of-cataract-services-in-north-west-nigeria-2005-2016
#17
Nasiru Muhammad, Mohammed Dantani Adamu, Mpyet Caleb, Nuhu Mohammed Maishanu, Aliyu Mohammed Jabo, Muhammad Mansur Rabiu, Covadonga Bascaran, Sunday Isiyaku, Allen Foster
PURPOSE: This study was conducted to assess the impact of the eye care programme on cataract blindness and cataract surgical services in Sokoto, Nigeria over a 12 year period 2005-2016. METHODS: Data from the 2005 population based cross-sectional study of blindness in Sokoto state was re-analysed to obtain baseline estimates of the prevalence of cataract blindness and cataract surgical coverage for persons 50 years and over in Wurno health zone. A population based survey of a representative sample of persons 50 years and over in Wurno health zone was conducted in July 2016...
2017: PloS One
https://www.readbyqxmd.com/read/28817556/risk-behaviors-for-contact-lens-related-eye-infections-among-adults-and-adolescents-united-states-2016
#18
Jennifer R Cope, Sarah A Collier, Hannah Nethercut, Jefferson M Jones, Kirsten Yates, Jonathan S Yoder
Contact lens-related eye infections, which can lead to serious outcomes, including blindness, are associated with several risk factors, including sleeping in lenses, exposing lenses to water, not adhering to replacement schedules, and reusing disinfecting solution (1). In some studies, adolescent and young adult contact lens wearers have been reported to be more likely than older adult contact lens wearers to develop eye infections (2,3) and more likely to have poor contact lens hygiene practices (2). In 2015, CDC reported the number and demographics of adult contact lens wearers in the United States to define the population at risk for contact lens-related eye infections (4); however, this estimate did not include adolescents...
August 18, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28817377/the-sustainable-professor
#19
Elizabeth S Haswell
Responsible agricultural practices provide a useful lens through which to consider the lives and careers of researchers.
August 17, 2017: ELife
https://www.readbyqxmd.com/read/28816867/peripheral-refraction-and-aberration-profiles-with-multifocal-lenses
#20
Cathleen Fedtke, Klaus Ehrmann, Varghese Thomas, Ravi C Bakaraju
SIGNIFICANCE: The amount of central or peripheral myopic shift, as induced by different multifocal contact lenses when viewing objects at distance or near, may provide insights on the potential efficacy for slowing eye growth. PURPOSE: The present study aims to compare peripheral refraction and higher-order aberration profiles of four multifocal contact lenses with a single vision control lens. METHODS: Thirty-five myopes (age 21.2 ± 2.1 years) completed the trial, of whom 16 wore Air Optix Aqua and Proclear Multifocal Distance and Near (group 1, spherical equivalent: -2...
August 14, 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
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