keyword
MENU ▼
Read by QxMD icon Read
search

cyto

keyword
https://www.readbyqxmd.com/read/28915439/alpha-mangostin-suppresses-interleukin-1%C3%AE-induced-apoptosis-in-rat-chondrocytes-by-inhibiting-the-nf-%C3%AE%C2%BAb-signaling-pathway-and-delays-the-progression-of-osteoarthritis-in-a-rat-model
#1
Tianlong Pan, Rong Chen, Dengying Wu, Ningyu Cai, Xuchao Shi, Bin Li, Jun Pan
Osteoarthritis (OA) is a chronic degenerative joint disease that is characterized by progressive joint dysfunction and pain. Apoptosis and catabolism in chondrocytes play critical roles in the development of OA. Alpha-Mangostin (α-MG), one of the main components of the mangosteen, has been reported to have anti-apoptotic, anti-inflammatory and antioxidant effects. We investigated the therapeutic effects of α-MG on OA through experiments on rat chondrocytes in vitro and in a rat model of OA induced by destabilization of the medial meniscus (DMM)...
September 12, 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/28913933/diagnostic-accuracy-of-fnac-and-cyto-histopathological-correlation-in-testicular-and-paratesticular-mass-lesions
#2
A D Singh, F A Wani, S Bhardwaj
OBJECTIVE: FNAC has a definitive role and has proved extremely useful in diagnosis of testicular and paratesticular mass lesions. In view of the dearth of literature of studies involving large cohorts of patients, the present study describes at length the detailed cytological evaluation of testicular and paratesticular mass lesions. METHODS: Our study consisted of 85 cases in 5-year retrospective and 1-year prospective analyses carried out in the Department of Pathology, Government Medical College, Jammu...
September 15, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/28913847/incidence-malignancy-rates-of-diagnoses-and-cyto-histological-correlations-in-the-new-italian-reporting-system-for-thyroid-cytology-an-institutional-experience
#3
P Straccia, A Santoro, E D Rossi, C Brunelli, C Mosseri, T Musarra, A Pontecorvi, C P Lombardi, G Fadda
OBJECTIVE: FNA biopsy is considered as the most accurate method for the selection of patients with thyroid nodules that need for surgery or for the wait and see management. The aim of the present study is to clarify the risk of malignancy for the cytological data classified according to the 2014 Italian reporting system. METHODS: We report a retrospective analysis of 4043 patients in our institution's experience during the period April 2014 through December 2016 with the Italian reporting system for thyroid cytology...
September 15, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/28895594/determination-of-spectral-markers-of-cytotoxicity-and-genotoxicity-using-in-vitro-raman-microspectroscopy-cellular-responses-to-polyamidoamine-dendrimer-exposure
#4
Esen Efeoglu, Alan Casey, Hugh J Byrne
Although consumer exposure to nanomaterials is ever increasing, with potential increased applications in areas such as drug and/or gene delivery, contrast agents and diagnosis, the determination of the cyto- and geno-toxic effects of nanomaterials on human health and the environment still remains challenging. Although many techniques have been established and adapted to determine the cytotoxicity and genotoxicity of nano-sized materials, these techniques remain limited by the number of assays required, total cost, and use of labels and they struggle to explain the underlying interaction mechanisms...
September 12, 2017: Analyst
https://www.readbyqxmd.com/read/28893919/antigen-localisation-influences-the-magnitude-and-kinetics-of-the-endogenous-adaptive-immune-response-to-recombinant-salmonella-vaccines
#5
Yanina R Sevastsyanovich, David R Withers, Claire L Marriott, Faye C Morris, Timothy J Wells, Douglas F Browning, Irene Beriotto, Ewan Ross, Hossam Omar Ali, Catherine A Wardius, Adam F Cunningham, Ian R Henderson, Amanda E Rossiter
The use of recombinant attenuated Salmonella vaccine (RASV) strains is a promising strategy to present heterologous antigens to the mammalian immune system to induce both cellular and humoral immune responses. However, studies on RASV development differ in where heterologous antigens are expressed and localised within the bacterium and it is unclear how antigen localisation modulates the immune response. Previously, we exploited the plasmid-encoded toxin (Pet) autotransporter system for accumulation of heterologous antigens in the cell culture supernatant...
September 11, 2017: Infection and Immunity
https://www.readbyqxmd.com/read/28887297/defining-optimal-triage-strategies-for-hrhpv-screen-positive-women-an-evaluation-of-hpv-16-18-genotyping-cytology-and-p16-ki-67-cyto-immunochemistry
#6
Grazyna A Stanczuk, Gwen J Baxter, Heather Currie, William Forson, James R Lawrence, Kate Cuschieri, Allan Wilson, Lynne Patterson, Lynn Govan, Janice Black, Tim Palmer, Marc Arbyn
BACKGROUND: Several options for the triage of high-risk HPV screen positive (hrHPV+) women were assessed. METHODS: This study incorporated CIN2+ cases and controls, all of whom tested hrHPV+ and whose results of liquid-based cytology (LBC), HPV16/18 genotyping and p16/Ki67 cyto-immunochemistry were available. Sensitivity and specificity for the CIN2+ of these triage tests were evaluated. RESULTS: Absolute sensitivities of HPV 16/18 typing, LBC and p16/Ki-67 cyto-immunochemistry for CIN2+ detection were 61...
September 8, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28886142/effects-of-ozone-exposure-on-human-epithelial-adenocarcinoma-and-normal-fibroblasts-cells
#7
Anna Poma, Sabrina Colafarina, Eleonora Aruffo, Osvaldo Zarivi, Antonella Bonfigli, Sebastiano Di Bucchianico, Piero Di Carlo
Previous studies show variable ozone cytotoxicity and genotoxicity in cell cultures, laboratory animals and humans directly exposed to tropospheric ozone. The aim of this study was therefore to investigate and compare the cyto and genotoxic effects of ozone using adenocarcinoma human alveolar basal epithelial cells A549 and normal human fibroblasts Hs27. A cell culture chamber with controlled atmosphere (a simulation reactor) was built to inject a flow of 120 ppb of ozone, which is two times the threshold value for the protection of human health, fixed by the EU legislation...
2017: PloS One
https://www.readbyqxmd.com/read/28883894/epigenetic-regulation-of-inflammation-in-localized-aggressive-periodontitis
#8
L M Shaddox, A F Mullersman, H Huang, S M Wallet, T Langaee, I Aukhil
BACKGROUND: We have previously demonstrated a Toll-like receptor (TLR)-mediated hyper-responsive phenotype in our cohort of localized aggressive periodontitis (LAP) individuals. However, mechanisms related to this phenotype are still not clear in the literature. The objective of this cross-sectional study is to examine the role of epigenetic regulation, specifically DNA methylation status of genes in the TLR pathway in this cohort. Peripheral blood was collected from 20 LAP patients and 20 healthy unrelated controls...
2017: Clinical Epigenetics
https://www.readbyqxmd.com/read/28878629/higher-arc-nucleus-to-cytoplasm-ratio-during-sleep-in-the-superficial-layers-of-the-mouse-cortex
#9
Sakiko Honjoh, Luisa de Vivo, Hiroyuki Okuno, Haruhiko Bito, Giulio Tononi, Chiara Cirelli
The activity-regulated cytoskeleton associated protein Arc is strongly and quickly upregulated by neuronal activity, synaptic potentiation and learning. Arc entry in the synapse is followed by the endocytosis of glutamatergic AMPA receptors (AMPARs), and its nuclear accumulation has been shown in vitro to result in a small decline in the transcription of the GluA1 subunit of AMPARs. Since these effects result in a decline in synaptic strength, we asked whether a change in Arc dynamics may temporally correlate with sleep-dependent GluA1 down-regulation...
2017: Frontiers in Neural Circuits
https://www.readbyqxmd.com/read/28877668/de-novo-assembly-of-phlomis-purpurea-after-challenging-with-phytophthora-cinnamomi
#10
Aladje Baldé, Dina Neves, Francisco J García-Breijo, Maria Salomé Pais, Alfredo Cravador
BACKGROUND: Phlomis plants are a source of biological active substances with potential applications in the control of phytopathogens. Phlomis purpurea (Lamiaceae) is autochthonous of southern Iberian Peninsula and Morocco and was found to be resistant to Phytophthora cinnamomi. Phlomis purpurea has revealed antagonistic effect in the rhizosphere of Quercus suber and Q. ilex against P. cinnamomi. Phlomis purpurea roots produce bioactive compounds exhibiting antitumor and anti-Phytophthora activities with potential to protect susceptible plants...
September 6, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28871510/cyto-histology-in-net-what-is-necessary-today-and-what-is-the-future
#11
REVIEW
Frediano Inzani, Gianluigi Petrone, Guido Fadda, Guido Rindi
The carcinoid as originally described is part of the relatively large family of neuroendocrine neoplasia found in almost every organ. Historical reasons back their current definitions. Neuroendocrine cancer is most frequently observed in the lung and the digestive tract. In the lung is defined as carcinoid (typical and atypical) for well differentiated, low to intermediate grade, and small cell and large cell neuroendocrine carcinoma for poorly differentiated, high grade. In the digestive system are respectively defined as neuroendocrine tumor (NET) and neuroendocrine carcinoma (NEC) of small and large cell types...
September 5, 2017: Reviews in Endocrine & Metabolic Disorders
https://www.readbyqxmd.com/read/28856781/cellular-apoptosis-and-cardiac-dysfunction-in-stz-induced-diabetic-rats-attenuated-by-anthocyanins-via-activation-of-igfi-r-pi3k-akt-survival-signaling
#12
Yin-Tso Liu, Pei-Chen Huang, Guei-Jane Wang, Ming-Jen Fan, Marthandam Asokan Shibu, Vijaya Padma Viswanadha, Yi-Lin Lin, Chao-Hung Lai, Yu-Feng Chen, Hung-En Liao, Chih-Yang Huang
Anthocyanins are known cyto-protective agents against various stress conditions. In this study cardio-protective effect of anthocyanins from black rice against diabetic mellitus (DM) was evaluated using a streptozotocin (STZ)-induced DM rat model. Five-week-old male Wistar rats were administered with STZ (55 mg kg(-1) , IP) to induce DM; rats in the treatment group received 250 mg oral anthocyanin/kg/day during the 4-week treatment period. DM and the control rats received normal saline through oral gavage...
August 30, 2017: Environmental Toxicology
https://www.readbyqxmd.com/read/28855837/in-vitro-cytotoxicity-and-cellular-uptake-studies-of-luminescent-functionalized-core-shell-nanospheres
#13
Anees A Ansari, T N Hasan, N A Syed, J P Labis, Ali A Alshatwi
Monodispersed luminescent functionalized core-shell nanospheres (LFCSNs) were successfully synthesized and investigated for their cyto-toxic effect on human liver hepatocellular carcinoma cell line (HepG2 cells) by adopting MTT, DNA Ladder, TUNEL assay and qPCR based gene expressions through mRNA quantifications. The TUNEL and DNA ladder assays suggested an insignificant apoptosis in HepG2 cells due to the LFCSNs treatment. Further, the qPCR results also show that the mRNA expressions of cell cycle checkpoint gene p53 and apoptosis related gene (caspase-9) was up-regulated, while the antiapoptotic gene BCl-2 and apoptosis related genes FADD and CAS-3 (apoptosis effecter gene) were down-regulated in the LFCSNs treated cells...
September 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/28854750/antioxidant-and-anti-inflammatory-properties-of-chicken-egg-vitelline-membrane-hydrolysates
#14
Dillon Lee, Fatemeh Bamdad, Kevin Khey, Hoon H Sunwoo
Vitelline membrane (VM) is a multilayered structure that surrounds the egg yolk serving to separate the yolk and the white. Due to its poor solubility in aqueous-based media, VM proteins and their biological properties have not been fully defined. In the current study, VM was hydrolyzed using different enzymes under the optimum hydrolysis conditions. Antioxidant and anti-inflammatory properties were evaluated in chemical and cellular models. Flavourzyme- and trypsin-treated samples showed the highest radical scavenging and ferric ion reducing effect (31% and 20 μM of Trolox equivalents/mg, respectively)...
September 1, 2017: Poultry Science
https://www.readbyqxmd.com/read/28852760/an-aptamer-bio-barcode-abc-assay-using-spr-rnase-h-and-probes-with-rna-and-gold-nanorods-for-anti-cancer-drug-screening
#15
Jacky Fong-Chuen Loo, Chengbin Yang, Hing Lun Tsang, Pui Man Lau, Ken-Tye Yong, Ho Pui Ho, Siu Kai Kong
With modifications to an ultra-sensitive bio-barcode (BBC) assay, we have developed a next generation aptamer-based bio-barcode (ABC) assay to detect cytochrome-c (Cyto-c), a cell death marker released from cancer cells, for anti-cancer drug screening. An aptamer is a short single-stranded DNA selected from a synthetic DNA library that is capable of binding to its target with high affinity and specificity based on its unique DNA sequence and 3D structure after folding. Similar to the BBC assay, Cyto-c is captured by a micro-magnetic particle (MMP) coated with capturing antibodies (Ab) and an aptamer specifically against Cyto-c to form sandwich structures ([MMP-Ab]-[Cyto-c]-[Aptamer])...
August 30, 2017: Analyst
https://www.readbyqxmd.com/read/28851322/portable-oct-assisted-surgical-treatment-of-intracorneal-pre-descemet-epithelial-cyst-a-case-report
#16
Sang Woo Kim, Eung Kweon Kim
BACKGROUND: Intracorneal epithelial cysts are a rare clinical condition that can occur anywhere in the corneal tissue; however, they appear most commonly in the stroma. They are sometimes challenging to treat because of their location, depth, and visual outcomes. Herein, we report a pre-Descemet epithelial cyst that was successfully treated surgically, with guidance from Fourier-domain optical coherence tomography (FD-OCT). CASE PRESENTATION: This interventional case report presents a patient with gradually decreasing vision caused by a pre-Descemet epithelial cyst...
August 29, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28844457/exposure-to-crack-cocaine-causes-adverse-effects-on-marine-mussels-perna-perna
#17
L A Maranho, M K Fontes, A S S Kamimura, C R Nobre, B B Moreno, F H Pusceddu, F S Cortez, D T Lebre, J R Marques, D M S Abessa, D A Ribeiro, C D S Pereira
Our study aimed to evaluate crack cocaine effects in different life stages of the marine mussel Perna perna. For this purpose, fertilization rate, embryo-larval development, lysosomal membrane stability and DNA strand breaks were assessed. Effect concentrations in gametes and in larval development were found after 1h (IC50=23.53mg·L(-1)) and 48h (IC50=16.31mg·L(-1)), respectively. The highest tested concentration showing no acute toxicity (NOEC) was 10mg·L(-1), while the lowest observed effect concentration (LOEC) was 20mg·L(-1)...
August 22, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28837272/corrigendum-to-quantification-methods-for-human-and-large-animal-leukocytes-using-dna-dyes-by-flow-cytometry-doi-10-1002-cyto-a-22874-cytometry-part-a-2016-89a-6-565-574
#18
(no author information available yet)
No abstract text is available yet for this article.
August 2017: Cytometry. Part A: the Journal of the International Society for Analytical Cytology
https://www.readbyqxmd.com/read/28837271/cyto-2017-award-recipients
#19
(no author information available yet)
No abstract text is available yet for this article.
August 2017: Cytometry. Part A: the Journal of the International Society for Analytical Cytology
https://www.readbyqxmd.com/read/28835616/leukocytic-toll-like-receptor-2-deficiency-preserves-cardiac-function-and-reduces-fibrosis-in-sustained-pressure-overload
#20
Jiong-Wei Wang, Magda S C Fontes, Xiaoyuan Wang, Suet Yen Chong, Elise L Kessler, Ya-Nan Zhang, Judith J de Haan, Fatih Arslan, Saskia C A de Jager, Leo Timmers, Toon A B van Veen, Carolyn S P Lam, Dominique P V de Kleijn
An involement of Toll-like receptor 2 (TLR2) has been established in cardiac dysfunction after acute myocardial infarction; however, its role in chronic pressure overload is unclear. We sought to evaluate the role of TLR2 in cardiac hypertrophy, fibrosis and dysfunction in sustained pressure overload. We induced pressure overload via transverse aortic constriction (TAC) in TLR2(-/-) and wild type (WT) mice, and followed temporal changes over 8 weeks. Despite similar increases in heart weight, left ventricular (LV) ejection fraction (EF) and diastolic function (mitral E/A ratio) were preserved in TLR2(-/-) mice but impaired in WT mice following TAC...
August 23, 2017: Scientific Reports
keyword
keyword
55331
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"