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https://www.readbyqxmd.com/read/29329819/the-effect-of-continuous-positive-airway-pressure-on-spectral-encephalogram-characteristics-in-stroke-patients-with-obstructive-sleep-apnea
#1
Hisham Alshaer, Aditya Pandya, Igor Zivanovic, Carolina Gonzaga Carvalho, Clodagh Ryan
OBJECTIVES: To evaluate if treatment with continuous positive airway pressure (CPAP) compared to usual care in stroke patients with obstructive sleep apnea (OSA) over one month reduces delta and alpha oscillations on quantitative electroencephalography (EEG) in association with improvements in cognitive or functional outcomes. METHODS: Spectral EEG analysis was performed in patients with subacute stroke and OSA randomized to usual care or CPAP treatment from a previous study...
January 9, 2018: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/29317418/home-polygraphic-recording-with-telemedicine-monitoring-for-diagnosis-and-treatment-of-sleep-apnoea-in-stroke-hopes-study-study-protocol-for-a-single-blind-randomised-controlled-trial
#2
Stefan Thomas Kotzian, Angela Schwarzinger, Sandra Haider, Bernd Saletu, Josef Spatt, Michael Timothy Saletu
INTRODUCTION: Meta-analyses report that more than 50% of patients who had a stroke suffer from moderate to severe sleep apnoea (SA), with adherence rates to positive airway pressure (PAP) therapy of only 30%. The primary objective of this study is to determine whether PAP adherence in patients who had a stroke with obstructive sleep apnoea (OSA) can be improved by a PAP training strategy during inhospital rehabilitation combined with a telemedicine monitoring system after discharge. Further objectives are (1) to compare the validity of a non-attended level-III polygraphy with that of a level-II polysomnography (PSG) in the diagnosis of SA, (2) to compare the validity of an apnoea-hypopnoea index (AHI) yielded by the PAP device with that obtained during PSG, (3) to determine changes in nocturnal systolic blood pressure (BP) due to PAP therapy with the pulse transit time (PTT) method and (4) to assess the impact of telemonitored PAP therapy on neurorehabilitation outcome parameters...
January 9, 2018: BMJ Open
https://www.readbyqxmd.com/read/29306892/association-of-body-flexibility-and-carotid-atherosclerosis-in-japanese-middle-aged-men-a-cross-sectional-study
#3
Masataka Suwa, Takayuki Imoto, Akira Kida, Takashi Yokochi, Mitsunori Iwase, Kenji Kozawa
OBJECTIVE: This study examined the associations of body flexibility with carotid arterial remodelling, including intima-media thickness (IMT) and plaque formation in middle-aged men. METHODS: The subjects of this cross-sectional study included 1354 Japanese men aged 35-59 years without histories of stroke or cardiac diseases. The arm extensibility test, which can estimate flexibility of the upper extremity (composed of shoulder external rotation and forearm supination), and the sit-and-reach test were performed...
January 5, 2018: BMJ Open
https://www.readbyqxmd.com/read/29299387/codeine-is-associated-with-poor-prognosis-in-acute-stroke
#4
Stian T Ryste, Bernt A Engelsen, Halvor Naess
Background: The aim of this study was to investigate how the use of analgesics, sleeping drugs, and sedatives relates to prognosis and complications in stroke patients in the acute care phase (≤48 hr) after a stroke. Materials and Methods: Patients with ischemic stroke, hemorrhagic stroke, and transient ischemic attack were included. The study is based on gathering of data on medication from 921 patient records belonging to patients included in the Bergen NORSTROKE registry, 12...
December 2017: Brain and Behavior
https://www.readbyqxmd.com/read/29288630/a-review-of-women-s-neurology
#5
REVIEW
M Angela O'Neal
The concern about what is best practice when caring for women with neurologic disease is a common clinical scenario. Therefore, knowledge about women's health issues and their intersection with neurologic disorders is imperative. This review will discuss the appropriate gender based considerations in epilepsy, multiple sclerosis, migraine, autoimmune disease, sleep, stroke and paraneoplastic disorders.
December 27, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/29286590/the-association-between-sleep-apnea-and-suicidal-thought-and-behavior-an-analysis-of-national-survey-data
#6
Todd M Bishop, Lisham Ashrafioun, Wilfred R Pigeon
OBJECTIVE: Sleep disturbances have been associated with increased risk for suicidal thought and behavior. The literature in regard to sleep and suicide, however, has focused predominantly on generalized sleep disturbance or insomnia. The purpose of the current study is to examine relationships among sleep apnea and suicidal thought and behavior using a nationally representative sample. METHODS: We conducted a secondary analysis of 2014 data from the National Survey on Drug Use and Health...
December 19, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29276708/association-between-sleep-patterns-and-health-in-families-with-exceptional-longevity
#7
Lavy Klein, Tina Gao, Nir Barzilai, Sofiya Milman
Background: Sleep patterns such as longer sleep duration or napping are associated with poor health outcomes. Although centenarians and their offspring demonstrate a delayed onset of age-related diseases, it is not known whether they have healthier sleep patterns or are protected against the negative effects of sleep disturbances. Methods: Data on sleep patterns and health history were collected from Ashkenazi Jewish subjects of the Longevity Genes Project using standardized questionnaires...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/29275335/association-of-obstructive-sleep-apnoea-with-the-risk-of-vascular-outcomes-and-all-cause-mortality-a-meta-analysis
#8
Chengjuan Xie, Ruolin Zhu, Yanghua Tian, Kai Wang
OBJECTIVE: This study aimed to conduct a meta-analysis to explore and summarise the evidence regarding the association between obstructive sleep apnoea (OSA) and the subsequent risk of vascular outcomes and all-cause mortality. METHODS: Electronic databases PubMed, Embase and the Cochrane Library were searched to identify studies conducted through May 2016. Prospective cohort studies that reported effect estimates with 95% CIs of major adverse cardiac events (MACEs), coronary heart disease (CHD), stroke, cardiac death, all-cause mortality and heart failure for different levels versus the lowest level of OSA were included...
December 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/29274045/overwork-accelerates-thrombotic-reaction-implications-for-the-pathogenesis-of-karoshi
#9
Kazunori Otsui, Junichiro Yamamoto, Nobutaka Inoue
Work-related stressors are potential causes of cardiovascular diseases (CVDs) and stroke; however, the pathophysiological mechanisms by which occupational stress induces and exacerbates CVDs remain unclear. The global thrombosis test (GTT) is a novel in vitro assay for evaluating both thrombotic reactions and subsequent thrombolysis. The time required to form an occlusive thrombus with the GTT, called as the occlusion time (OT), and the time to lyse the thrombus, the lysis time (LT), are markers of thrombotic and thrombolytic reactions, respectively...
December 22, 2017: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/29259576/obstructive-sleep-apnea-phenotypes-and-markers-of-vascular-disease-a-review
#10
REVIEW
Alberto R Ramos, Pedro Figueredo, Shirin Shafazand, Alejandro D Chediak, Alexandre R Abreu, Salim I Dib, Carlos Torre, Douglas M Wallace
Obstructive sleep apnea (OSA) is a chronic and heterogeneous disorder that leads to early mortality, stroke, and cardiovascular disease (CVD). OSA is defined by the apnea-hypopnea index, which is an index of OSA severity that combines apneas (pauses in breathing) and hypopneas (partial obstructions in breathing) associated with hypoxemia. Yet, other sleep metrics (i.e., oxygen nadir, arousal frequency), along with clinical symptoms and molecular markers could be better predictors of stroke and CVD outcomes in OSA...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29258470/health-and-healthcare-disparities-among-u-s-women-and-men-at-the-intersection-of-sexual-orientation-and-race-ethnicity-a-nationally-representative-cross-sectional-study
#11
Mai-Han Trinh, Madina Agénor, S Bryn Austin, Chandra L Jackson
BACKGROUND: Research has shown that sexual minorities (SMs) (e.g. lesbian, gay, and bisexual individuals), compared to their heterosexual counterparts, may engage in riskier health behaviors, are at higher risk of some adverse health outcomes, and are more likely to experience reduced health care access and utilization. However, few studies have examined how the interplay between race and sexual orientation impacts a range of health measures in a nationally representative sample of the U...
December 19, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29250279/baseline-demographics-safety-and-patient-acceptance-of-an-insertable-cardiac-monitor-for-atrial-fibrillation-screening-the-reveal-af-study
#12
Sergio Conti, James A Reiffel, Bernard J Gersh, Peter R Kowey, Rolf Wachter, Jonathan L Halperin, Rachelle E Kaplon, Erika Pouliot, Atul Verma
Given the high prevalence and risk of stroke associated with atrial fibrillation (AF), detection strategies have important public health implications. The ongoing prospective, single-arm, open-label, multicenter REVEAL AF trial is evaluating the incidence of previously undetected AF using an insertable cardiac monitor (ICM) in patients without prior AF or device implantation, but who could be at risk for AF due to their demographic characteristics, +/- non-specific but compatible symptoms. Enrollment required an elevated AF risk profile defined as CHADS2≥3 or CHADS2=2 plus one or more of the following: coronary artery disease, renal impairment, sleep apnea or chronic obstructive pulmonary disease...
February 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29247523/impact-of-obstructive-sleep-apnea-on-cardiovascular-outcomes-in-patients-with-acute-symptomatic-pulmonary-embolism-rationale-and-methodology-for-the-pope-study
#13
Eva Mañas, Esther Barbero, Diana Chiluiza, Aldara García, Raquel Morillo, Deisy Barrios, Miguel Ángel Martínez-García, Alicia Albalat, Irene Cano, David Jiménez
In normotensive patients with acute symptomatic pulmonary embolism (PE), the effect of undiagnosed obstructive sleep apnea (OSA) on cardiovascular (CV) outcomes lacks clarity. The Prognostic Significance of Obstructive Sleep Apnea in Patients With Acute Symptomatic Pulmonary Embolism (POPE) study is a multicenter, observational study designed to prospectively assess the prognostic significance of concomitant OSA in hemodynamically stable outpatients with acute symptomatic PE. Adult patients with acute stable PE are eligible...
December 16, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/29236821/the-critical-influence-of-nocturnal-breathing-complaints-on-the-quality-of-sleep-after-stroke-the-pittsburgh-sleep-quality-index-and-stop-bang
#14
Giuliano da Paz Oliveira, Eliana Regina Lottemberg Vago, Gilmar Fernandes do Prado, Fernando Morgadinho Santos Coelho
In stroke patients particularly, many factors, such as sleep-related respiratory disturbances, can impair sleep. Cheap and easy-to-use tools have been created to identify sleep quality and sleep disturbances in patients after stroke. This study described the scores of the sleep apnea screening questionnaire - STOP-BANG - in patients after a stroke, and correlated the findings with sleep quality measured by the Pittsburgh Sleep Quality Index (PSQI). The scores of the STOP-BANG and PSQI were 4.3 ± 1.8 and 76 ± 3...
November 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/29235430/prevalence-and-risk-factors-for-delirium-diagnosis-in-patients-followed-in-general-practices-in-germany
#15
Jens Bohlken, Karel Kostev
BACKGROUND: The aim of this study is to identify the prevalence and risk factors of documented delirium in general practices in Germany. METHODS: The present study includes 2,194 patients over the age of 65 years with delirium and 2,194 controls without delirium from a sample of 6,180,042 patients from 1,262 general practices. Multivariate logistic regression models were fitted with delirium as a dependent variable and other disorders and drugs as potential predictors...
December 13, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/29231496/-acupuncture-combined-with-auricular-point-sticking-therapy-for-post-stroke-depression-a-randomized-controlled-trial
#16
Lin Zhang, Yan Zhong, Shulin Quan, Yehui Liu, Xuehui Shi, Zhenguang Li, Jingjing Wang
OBJECTIVE: To observe the clinical effects of acupuncture combined with auricular point sticking based on the western medication for post stroke depression (PSD). METHODS: Sixty patients with PSD were randomly assigned into an acupuncture plus auricular application group (a combination group) and a medication group, 30 cases in each one. 20 mg paroxetine hydrochloride was prescribed orally in the medication group, once a day for continuous 8 weeks. Based on the above treatment, 30-minute acupuncture was used in the combination group for 8 weeks at Baihui (GV 20), Sishencong (EX-HN 1), Shenting (GV 24), Yintang (GV 29), Shenmen (HT 7), Neiguan (PC 6), Taichong (LR 3), Hegu (LI 4), Zusanli (ST 36), Sanyinjiao (SP 6) and Fenglong (ST 40), once the other day and three times a week...
June 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29222290/chronic-organ-failure-in-adult-sickle-cell-disease
#17
REVIEW
Elliott Vichinsky
Sickle cell disease is now a chronic adult illness characterized by progressive multiorgan failure, particularly involving the brain and kidney. The etiology is multifactorial; it includes hemolysis and nitric oxide deficiency. As patients age, most experience neurologic insult. Twenty-five percent of older adults have had a clinical stroke and at least half of the population have had a silent infarct, cortical atrophy, and neurocognitive impairment. Periodic screening with neuroimaging and neurocognitive testing is recommended...
December 8, 2017: Hematology—the Education Program of the American Society of Hematology
https://www.readbyqxmd.com/read/29221777/prevalence-of-sleep-apnea-at-the-acute-phase-of-ischemic-stroke-with%C3%A2-or-without-thrombolysis
#18
Jaana K Huhtakangas, Juha Huhtakangas, Risto Bloigu, Tarja Saaresranta
OBJECTIVE: The aim of the study was to compare the prevalence, type, and severity of sleep apnea during the acute phase of ischemic stroke among patients either receiving or not receiving thrombolysis. METHODS: We recruited 246 consecutive adult ischemic stroke patients. Patients underwent cardiorespiratory sleep study with portable three-channel device during the first 48 h after the symptom onset of ischemic stroke. RESULTS: We enrolled 110 (65...
December 2017: Sleep Medicine
https://www.readbyqxmd.com/read/29201813/risk-factors-and-functional-impact-of-medical-complications-in-stroke
#19
Bo-Ram Kim, Jongmin Lee, Min Kyun Sohn, Deog Young Kim, Sam-Gyu Lee, Yong-Il Shin, Gyung-Jae Oh, Yang-Soo Lee, Min Cheol Joo, Eun Young Han, Yun-Hee Kim
Objective: To determine the incidence and risk factors for medical complications in Korean patients suffering from stroke and the impact of such complications on post-stroke functional outcomes. Methods: We assessed patients enrolled in a prospective cohort study. All recruited patients had suffered a first acute stroke episode and been admitted to nine university hospitals in Korea between August 2012 and June 2015. We analyzed patient and stroke characteristics, comorbidities, prevalence of post-stroke medical complications, and functional outcomes at time of discharge and 3, 6, and 12 months after stroke onset...
October 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29198297/sleep-apnea-in-patients-hospitalized-with-acute-ischemic-stroke-underrecognition-and-associated-clinical-outcomes
#20
Nura Festic, David Alejos, Vikas Bansal, Lesia Mooney, Paul A Fredrickson, Pablo R Castillo, Emir Festic
STUDY OBJECTIVES: To evaluate clinical recognition of sleep apnea and related outcomes in patients hospitalized with acute ischemic stroke. METHODS: A retrospective study of all patients hospitalized with acute ischemic stroke from April 2008 to December 2014. The primary predictor and outcome variables were sleep apnea and hospital mortality, respectively. Secondary outcomes were mechanical ventilation, hospital length of stay, and the survivor's functional level by the modified Rankin scale...
November 29, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
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