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https://www.readbyqxmd.com/read/27913972/in-hospital-diagnosis-of-sleep-apnea-in-stroke-patients-using-a-portable-acoustic-device
#1
Clodagh M Ryan, Kelly Wilton, T Douglas Bradley, Hisham Alshaer
PURPOSE: Sleep apnea (SA) is highly prevalent in post-stroke patients. Due to physical disability and relative inaccessibility of polysomnography (PSG) to test for SA, patients with stroke frequently remain undiagnosed and untreated. Portable SA monitoring can facilitate at-home or in-hospital testing for SA. However, portable SA monitoring is not recommended in those with complex medical conditions, such as stroke, due to the lack of validation of portable monitoring in such patients...
December 2, 2016: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/27911316/risk-factors-for-mild-cognitive-impairment-in-german-primary-care-practices
#2
Louis Jacob, Jens Bohlken, Karel Kostev
BACKGROUND: Mild cognitive impairment (MCI) is a common mental disorder affecting around 16% of elderly people without dementia. MCI is considered an intermediate state between normal cognition and dementia. OBJECTIVE: To analyze risk factors for the development of MCI in German primary care practices. METHODS: In total, 3,604 MCI patients and 3,604 controls without MCI were included between January 2010 and December 2015. Several disorders potentially associated with MCI were determined...
December 1, 2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/27893291/association-between-use-of-short-acting-benzodiazepines-and-migraine-occurrence-a-nationwide-population-based-case-control-study
#3
Tomor Harnod, Yu-Chiao Wang, Cheng-Li Lin, Chun-Hung Tseng
AIM: To evaluate the association between using benzodiazepines (BZDs) with short- or long-acting durations and migraine occurrence. METHODS: 9616 subjects aged older than 20 years and newly diagnosed with migraine between 2005 and 2011 comprised the migraine group, and 38464 subjects without migraine comprised the comparison group. The BZDs used in the subjects were dichotomously defined as short-acting (half-life ≤24 h) and long-acting substances. Logistic regression model was used to calculate the odds ratio (OR) of migraine associated with BZD exposure and other diseases...
November 28, 2016: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/27891299/tourette-syndrome-and-comorbid-neuropsychiatric-conditions
#4
REVIEW
Ashutosh Kumar, William Trescher, Debra Byler
Tourette syndrome is a neuropsychiatric condition characterized by both motor and phonic tics over a period of at least 1 year with the onset in childhood or adolescence. Apart from the tics, most of the patients with Tourette syndrome have associated neuropsychiatric comorbidities consisting of attention deficit hyperactivity disorder, obsessive compulsive disorder, rage attacks, sleep issues, depression, and migraine. Patients may also have physical complications directly from violent motor tics which can rarely include cervical myelopathy, arterial dissection, and stroke...
2016: Current Developmental Disorders Reports
https://www.readbyqxmd.com/read/27878815/interventions-to-reduce-cognitive-impairments-following-critical-illness-a-topical-systematic-review
#5
REVIEW
H K Nedergaard, H I Jensen, P Toft
BACKGROUND: Critical illness is associated with cognitive impairments. Effective treatment or prevention has not been established. The aim of this review was to create a systematic summary of the current evidence concerning clinical interventions during intensive care admission to reduce cognitive impairments after discharge. METHODS: Medline, Embase, Cochrane Central, PsycInfo and Cinahl were searched. Inclusion criteria were studies assessing the effect of interventions during intensive care admission on cognitive function in adult patients...
November 22, 2016: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/27852282/effect-of-acupuncture-on-insomnia-following-stroke-study-protocol-for-a-randomized-controlled-trial
#6
Yan Cao, Xuan Yin, Francisca Soto-Aguilar, Yiping Liu, Ping Yin, Junyi Wu, Bochang Zhu, Wentao Li, Lixing Lao, Shifen Xu
BACKGROUND: The incidence, mortality, and prevalence of stroke are high in China. Stroke is commonly associated with insomnia; both insomnia and stroke have been effectively treated with acupuncture for a long time. The aim of this proposed trial is to assess the therapeutic effect of acupuncture on insomnia following stroke. METHODS: This proposed study is a single-center, single-blinded (patient-assessor-blinded), parallel-group randomized controlled trial. We will randomly assign 60 participants with insomnia following stroke into two groups in a 1:1 ratio...
November 16, 2016: Trials
https://www.readbyqxmd.com/read/27823712/sleep-apnea-syndrome-and-patent-foramen-ovale-a-dangerous-association-in-ischemic-stroke
#7
Silvia Tur, Mónica de la Peña, Bárbara Vives, Ana Belén Martínez, Arantza Gorospe, Inés Legarda, Maria José Torres, Carmen Jiménez, Joan B Soriano
BACKGROUND: The coexistence of patent foramen ovale (PFO) and sleep apnea syndrome (SAS) might be related to the pathogenesis of cryptogenic stroke (CS). We aimed to determine the prevalence of SAS in patients with cryptogenic stroke and PFO. METHODS: This is a prospective case-control study in which we included ischemic stroke patients consecutively admitted to our hospital's Acute Stroke Unit. Contrast transcranial Doppler (c-TCD) and sleep polygraphy within the first 72 h after stroke onset were performed to detect PFO and SAS...
September 2016: Sleep Medicine
https://www.readbyqxmd.com/read/27822340/stem-progenitor-cells-and-obstructive-sleep-apnea-syndrome-new-insights-for-clinical-applications
#8
REVIEW
Miruna Mihaela Micheu, Ana-Maria Rosca, Oana-Claudia Deleanu
Obstructive sleep apnea syndrome (OSAS) is a widespread disorder, characterized by recurrent upper airway obstruction during sleep, mostly as a result of complete or partial pharyngeal obstruction. Due to the occurrence of frequent and regular hypoxic events, patients with OSAS are at increased risk of cardiovascular disease, stroke, metabolic disorders, occupational errors, motor vehicle accidents and even death. Thus, OSAS has severe consequences and represents a significant economic burden. However, some of the consequences, as well as their costs can be reduced with appropriate detection and treatment...
October 26, 2016: World Journal of Stem Cells
https://www.readbyqxmd.com/read/27803010/health-consequences-of-shift-work-and-insufficient-sleep
#9
REVIEW
Göran Kecklund, John Axelsson
This review summarises the literature on shift work and its relation to insufficient sleep, chronic diseases, and accidents. It is based on 38 meta-analyses and 24 systematic reviews, with additional narrative reviews and articles used for outlining possible mechanisms by which shift work may cause accidents and adverse health. Evidence shows that the effect of shift work on sleep mainly concerns acute sleep loss in connection with night shifts and early morning shifts. A link also exists between shift work and accidents, type 2 diabetes (relative risk range 1...
November 1, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27754232/os-33-08-obstructive-sleep-apnea-promotes-cardiovascular-risk-in-hypertensive-populations-a-cross-sectional-study
#10
Anping Cai, Ling Wang, Yingling Zhou, Jiyan Chen, Yingqing Feng, Qi Zhong
OBJECTIVE: Current study sought to evaluate the effects of obstructive sleep apnea (OSA) plus hypertension (HTN) on prevalent cardiovascular diseases (CVD). DESIGN AND METHOD: This was a cross-sectional study and a total of 1889 subjects were enrolled. The apnea-hypopnea index (AHI) was measured by polysomnography and OSA degree was classified as mild (AHI 5-14.9) and moderate-severe (AHI ≥ 15), and AHI < 5 was considered no-OSA. Mean and lowest oxyhemoglobin saturation (SaO2) was detected by pulse oximetry...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753975/os-12-02-sleep-apnea-cardiovascular-endpoints-save-study-an-international-randomised-controlled-trial-to-determine-whether-continuous-positive-airways-pressure-treatment-for-obstructive-sleep-apnea-in-patients-with-cv-disease-prevents-secondary-cardiovascular
#11
Craig Anderson, Doug McEvoy, Jiguang Wang
OBJECTIVE: There is uncertainty over whether treatment of obstructive sleep apnea (OSA) can prevent serious cardiovascular (CV) events. DESIGN AND METHOD: SAVE (NCT00738179; ACTRN12608000409370) was designed to determine whether treatment of OSA with CPAP reduces the risk of serious CV events in patients with established CV disease. Participants were centrally randomised to CPAP treatment or usual care between 2008 and 2013,with follow-up completed late 2015 and the results will be announced in August 2016...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753946/os-07-02-differences-in-circadian-blood-pressure-variability-patterns-between-japanese-and-american-treatment-resistant-hypertensive-populations
#12
Kazuomi Kario, Deepak Bhatt, Sandeep Brar, George Bakris
OBJECTIVE: Dynamic changes in 24-hour ambulatory blood pressure (BP) are associated with basal autonomic function and cardiovascular risk. We examined the influence of ethnicity on these parameters by comparing ambulatory BP dynamics in Japanese, African American (AA), and white populations with treatment-resistant hypertension. DESIGN AND METHOD: Both HTN-Japan (N = 41) and SYMPLICITY HTN-3 (N = 384 white and 140 AA) enrolled patients with office systolic BP ≥ 160 mmHg and 24-hour ambulatory systolic BP ≥ 135 mmHg while on ≥3 antihypertensive medications...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753860/me-01-2-assessment-and-treatment-of-morning-hypertension-update
#13
Kazuomi Kario
The essential benefit of the management of hypertension is derived from the blood pressure (BP) lowering per se, indicating the importance of BP throughout 24 hours. Recent guidelines stressed the importance of home BP for the diagnosis and management of hypertension. It is well-known that cardiovascular events occur more frequently in the morning BP levels have been shown to increase during the period from night to early morning. Clinical research using ambulatory BP monitoring (ABPM) or home BP monitoring has clarified that morning BP and BP surge are more closely related to the cardiovascular risk than office BP (Kario et al...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753839/sy-06-3-role-of-surgical-treatment-of-morbid-obesity
#14
Wei-Jei Lee
Obesity is a pan-endemic health problem in both developed and developing countries, in both western and eastern countries. It increases risk for many common diseases, including type 2 diabetes, dyslipidemia, hypertension, obstructive sleep apnea, heart disease, stroke, asthma, osteoarthritis, cancers and depression etc.. Although the incidence of obesity in Asia is relatively low, Asian patients tend to have similar incidence of obesity related metabolic syndrome at lower BMI level comparing to Caucasians because of central obesity...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753832/sy-04-2-long-term-cvd-risk-prediction-in-low-incidence-european-populations
#15
Giovanni Veronesi
In Italy, the European SCORE Project risk score is the recommended tool for cardiovascular disease risk stratification in the primary prevention setting. Among non-diabetic subjects aged 40 to 64, the model estimates the 10-year probability of death due to cardiovascular disease based on individual's age, total cholesterol, blood pressure and smoking status. A growing body of evidence suggests that in middle-aged adults this stratification may suffer from two major drawbacks. First, mortality risk severely underestimates the global burden of disease incidence...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753673/a-narrative-review-of-how-sleep-related-breathing-disorders-and-cardiovascular-diseases-are-linked-an-update-for-advanced-practice-registered-nurses
#16
Chooza Moon, Cynthia H Phelan, Diane R Lauver, Lisa C Bratzke
PURPOSE/OBJECTIVES: Sleep-related breathing disorders (SRBDs), including obstructive sleep apnea and central sleep apnea, are common among patients with cardiovascular disease (CVD), but clinicians often do not pay enough attention to SRBDs. The purpose of this narrative review is to update advanced practice registered nurses on the literature focusing on the relationship between SRBDs and CVD (eg, hypertension, heart failure, coronary artery disease, arrhythmias, and stroke) and on treatments that can improve SRBDs in patients with CVD...
November 2016: Clinical Nurse Specialist CNS
https://www.readbyqxmd.com/read/27749332/central-poststroke-pain-can-occur-with-normal-sensation
#17
Ajit Kumar, Sanjeev K Bhoi, Jayantee Kalita, Usha K Misra
OBJECTIVE: In view of the paucity of studies on central poststroke pain (CPSP), in this hospital-based prospective study, we evaluated the frequency, the spectrum, imaging, and quantitative sensory testing in a cohort of stroke patients with CPSP. METHODS: Stroke patients who developed CPSP at onset or during follow-up were included. Patients were subjected to clinical evaluation and sensory testing. The severity of stroke was defined by the Modified Rankin Scale and disability by the Barthel Index...
November 2016: Clinical Journal of Pain
https://www.readbyqxmd.com/read/27748200/statins-may-prevent-atherosclerotic-disease-in-osa-patients-without-co-morbidities
#18
Domenico Maurizio Toraldo, Michele De Benedetto, Luana Conte, Francesco De Nuccio
Obstructive sleep apnea (OSA) is characterized by repetitive interruptions of breathing, causing a Chronic Intermittent Hypoxia (CIH) that can be a key step in the development and progression of cardiovascular diseases. Nowadays, in fact, there is scientific evidence showing the close relationship between OSA and atherosclerosis, even in those patients who do not show co-morbidities such as hypertension, diabetes, high levels of low-density lipoprotein (LDL), cigarette smoking and obesity, which normally are able to activate the endothelium...
October 7, 2016: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/27743803/short-sleep-duration-and-health-outcomes-a-systematic-review-meta-analysis-and-meta-regression
#19
Osamu Itani, Maki Jike, Norio Watanabe, Yoshitaka Kaneita
OBJECTIVE: The dose-response of short sleep duration in mortality has been studied, in addition to the incidences of notable health complications and diseases such as diabetes mellitus, hypertension, cardiovascular diseases, stroke, coronary heart diseases, obesity, depression, and dyslipidemia. METHODS: We collected data from prospective cohort studies with follow-ups of one year or more on associations between short sleep duration and the outcomes. For the independent variable, we divided participants at baseline into short sleepers and normal sleepers...
August 26, 2016: Sleep Medicine
https://www.readbyqxmd.com/read/27739821/unified-model-of-brain-tissue-microstructure-dynamically-binds-diffusion-and-osmosis-with-extracellular-space-geometry
#20
Mohsen Yousefnezhad, Morteza Fotouhi, Kaveh Vejdani, Padideh Kamali-Zare
We present a universal model of brain tissue microstructure that dynamically links osmosis and diffusion with geometrical parameters of brain extracellular space (ECS). Our model robustly describes and predicts the nonlinear time dependency of tortuosity (λ=sqrt[D/D^{*}]) changes with very high precision in various media with uniform and nonuniform osmolarity distribution, as demonstrated by previously published experimental data (D = free diffusion coefficient, D^{*} = effective diffusion coefficient). To construct this model, we first developed a multiscale technique for computationally effective modeling of osmolarity in the brain tissue...
September 2016: Physical Review. E
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