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https://www.readbyqxmd.com/read/29136234/non-apnoea-sleep-disorder-increases-the-risk-of-subsequent-female-infertility-a-nationwide-population-based-cohort-study
#1
I-Duo Wang, Yung-Liang Liu, Chung-Kan Peng, Chi-Hsiang Chung, Shan-Yueh Chang, Chang-Huei Tsao, Wu-Chien Chien
Study Objectives: Non-apnoea sleep disorder (NASD) increases the risk of hypertension, type 2 diabetes mellitus (DM), chronic kidney disease (CKD), cardiovascular disease and stroke. However, the risk and the time interval of NASD to female infertility has not been thoroughly understood. Our study aimed to determine whether NASD increases subsequent risk of female infertility. Methods: This study utilized outpatient and inpatient data from the Longitudinal Health Insurance Database (LHID) between 2000 and 2010 in Taiwan...
November 9, 2017: Sleep
https://www.readbyqxmd.com/read/29131369/photobiomodulation-for-traumatic-brain-injury-and-stroke
#2
REVIEW
Michael R Hamblin
There is a notable lack of therapeutic alternatives for what is fast becoming a global epidemic of traumatic brain injury (TBI). Photobiomodulation (PBM) employs red or near-infrared (NIR) light (600-1100nm) to stimulate healing, protect tissue from dying, increase mitochondrial function, improve blood flow, and tissue oxygenation. PBM can also act to reduce swelling, increase antioxidants, decrease inflammation, protect against apoptosis, and modulate microglial activation state. All these mechanisms of action strongly suggest that PBM delivered to the head should be beneficial in cases of both acute and chronic TBI...
November 13, 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/29126756/-vascular-dysfunction-in-obstructive-sleep-apnoea-implication-of-microparticules
#3
REVIEW
W Trzepizur, P Priou, N Meslier, T Urban, M C Martínez, R Andriantsitohaina, F Gagnadoux
Obstructive sleep apnea (OSA) is associated with increased cardiovascular diseases, including myocardial infarction and stroke and promotes cardiovascular risk factors including diabetes and hypertension. OSA has also been proposed to have a direct proatherogenic effects. Recent studies have investigated the role of microparticles (MPs) in the atherogenic process. MPs are small plasma membrane vesicles that can be released by a variety of vascular or blood cells and that contain membrane and cytosolic elements...
November 7, 2017: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/29119068/ischemic-stroke-of-midbrain-and-cerebellum-involving-reticular-activating-system
#4
Waleed Sadiq, Madeeha Subhan
The reticular activating system is the part of the brain that maintains the sleep/wake cycle. Any damage to this region can cause hypersomnolence and drowsiness along with altered sensorium. This case presents a patient with cerebellar and midbrain stroke with infarct of the reticular activating system, leading to hypersomnolence, drowsiness, and altered sensorium.
September 1, 2017: Curēus
https://www.readbyqxmd.com/read/29117882/excessive-daytime-sleepiness-in-acute-ischemic-stroke-association-with-restless-legs-syndrome-diabetes-mellitus-obesity-and-sleep-disordered-breathing
#5
Pavel Šiarnik, Katarína Klobučníková, Pavol Šurda, Matúš Putala, Stanislav Šutovský, Branislav Kollár, Peter Turčáni
STUDY OBJECTIVES: Sleep disorders are frequent in stroke patients. The prevalence of sleep-disordered breathing (SDB), excessive daytime sleepiness (EDS), and restless legs syndrome (RLS) among stroke survivors is up to 91%, 72%, and 15%, respectively. Although the relationship between EDS and SDB is well described, there are insufficient data regarding the association of EDS with RLS. The aim of this study was to explore the association between EDS, SDB, and RLS in acute ischemic stroke...
November 1, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29114090/sleep-preconditioning-and-stroke
#6
Alessandro Pincherle, Marta Pace, Simone Sarasso, Laura Facchin, Jens P Dreier, Claudio L Bassetti
No abstract text is available yet for this article.
November 7, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29112823/obstructive-sleep-apnea-during-rapid-eye-movement-sleep-and-cardiovascular-disease
#7
R Nisha Aurora, Ciprian Crainiceanu, Daniel J Gottlieb, Ji Soo Kim, Naresh M Punjabi
BACKGROUND: Obstructive sleep apnea (OSA) during rapid eye movement (REM) sleep is a common disorder. Data on whether OSA that occurs predominantly during REM sleep is associated with health outcomes are limited. The present study examined the association between OSA during REM sleep and a composite cardiovascular endpoint in a community sample with and without prevalent cardiovascular disease. METHODOLOGY: Full montage home polysomnography was conducted as part of the Sleep Heart Health Study...
November 7, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29109195/sleep-apnea-and-cardiovascular-disease-lessons-from-recent-trials-and-need-for-team-science
#8
REVIEW
Luciano F Drager, R Doug McEvoy, Ferran Barbe, Geraldo Lorenzi-Filho, Susan Redline
Emerging research highlights the complex interrelationships between sleep-disordered breathing and cardiovascular disease, presenting clinical and research opportunities as well as challenges. Patients presenting to cardiology clinics have a high prevalence of obstructive and central sleep apnea associated with Cheyne-Stokes respiration. Multiple mechanisms have been identified by which sleep disturbances adversely affect cardiovascular structure and function. Epidemiological research indicates that obstructive sleep apnea is associated with increases in the incidence and progression of coronary heart disease, heart failure, stroke, and atrial fibrillation...
November 7, 2017: Circulation
https://www.readbyqxmd.com/read/29108611/positive-airway-pressure-therapy-for-hyperventilatory-central-sleep%C3%A2-apnea-idiopathic-heart-failure-cerebrovascular-disease-and-high-altitude
#9
REVIEW
Shahrokh Javaheri, Lee K Brown
Central sleep apnea (CSA) and Hunter-Cheyne-Stokes breathing (HCSB) are caused by failure of the pontomedullary pacemaker generating breathing rhythm. CSA/HCSB may complicate several disorders causing recurrent arousals and desaturations. Common causes of CSA in adults are congestive heart failure, stroke, and chronic use of opioids; opioids have hypoventilatory effects. Diagnosis and treatment of hyperventilatory CSA may improve quality of life, and, when associated with heart failure or cerebrovascular disease, reduce morbidity and perhaps mortality...
December 2017: Sleep Medicine Clinics
https://www.readbyqxmd.com/read/29107556/-blood-pressure-and-sleep-apnoea-hypopnoea-syndrome-in-workers-stop-bang-test-versus-epworth-test
#10
M T Vicente-Herrero, L Capdevila-García, M C Bellido-Cambrón, M V Ramírez-Iñiguez de la Torre, S Lladosa-Marco
INTRODUCTION: OSAHS is associated with an increased risk of cardiovascular disease and stroke. Arterial hypertension is a key risk factor to consider due to its impact on health. METHOD: Cross-sectional study carried out on Spanish public service workers. The nocturnal apnoea risk using the Epworth and STOP-Bang questionnaires and their influence on the mean values of blood pressure are assessed. RESULTS: The detection of OSAHS using the Epworth test and, particularly with the STOP-Bang shows a significant relationship with the mean values of blood pressure, with differences between both questionnaires...
October 26, 2017: Hipertensión y Riesgo Vascular
https://www.readbyqxmd.com/read/29106402/selective-neuronal-lapses-precede-human-cognitive-lapses-following-sleep-deprivation
#11
Yuval Nir, Thomas Andrillon, Amit Marmelshtein, Nanthia Suthana, Chiara Cirelli, Giulio Tononi, Itzhak Fried
Sleep deprivation is a major source of morbidity with widespread health effects, including increased risk of hypertension, diabetes, obesity, heart attack, and stroke. Moreover, sleep deprivation brings about vehicle accidents and medical errors and is therefore an urgent topic of investigation. During sleep deprivation, homeostatic and circadian processes interact to build up sleep pressure, which results in slow behavioral performance (cognitive lapses) typically attributed to attentional thalamic and frontoparietal circuits, but the underlying mechanisms remain unclear...
November 6, 2017: Nature Medicine
https://www.readbyqxmd.com/read/29094912/recurrent-ischemic-stroke-strategies-for-prevention
#12
Rupal Oza, Kristen Rundell, Miriam Garcellano
Recurrent strokes make up almost 25% of the nearly 800,000 strokes that occur annually in the United States. Risk factors for ischemic stroke include hypertension, diabetes mellitus, hyperlipidemia, sleep apnea, and obesity. Lifestyle modifications, including tobacco cessation, decreased alcohol use, and increased physical activity, are also important in the management of patients with a history of stroke or transient ischemic attack. Antiplatelet therapy is recommended to reduce the risk of recurrent ischemic stroke...
October 1, 2017: American Family Physician
https://www.readbyqxmd.com/read/29080583/prediabetes-beyond-the-borderline
#13
REVIEW
Mara Lynn Wilson
Prediabetes is a complex multifactorial metabolic disorder that extends beyond glucose control. Current studies have found that microvascular disease (neuropathy, nephropathy, and retinopathy), macrovascular disease (stroke, coronary artery disease, and peripheral vascular disease), periodontal disease, cognitive dysfunction, blood pressure changes, obstructive sleep apnea, low testosterone level, fatty liver disease, and cancer are some of conditions that are present with the onset of glycemic dysregulation...
December 2017: Nursing Clinics of North America
https://www.readbyqxmd.com/read/29078781/physical-chronic-conditions-multimorbidity-and-sedentary-behavior-amongst-middle-aged-and-older-adults-in-six-low-and-middle-income-countries
#14
Davy Vancampfort, Brendon Stubbs, Ai Koyanagi
BACKGROUND: Sedentary behavior (SB) is, irrespective of a person's physical activity levels, associated with a wide range of deleterious outcomes such as diabetes, stroke and associated premature mortality. There are no nationally representative, multi-national, population-based studies investigating the relationship between SB, chronic conditions, and physical multimorbidity (i.e., two or more chronic physical conditions). Thus, this cross-sectional study aimed to assess the association between chronic conditions, physical multimorbidity and SB among community-dwelling adults in six low- and middle-income countries (LMICs)...
October 27, 2017: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/29074066/dysphagia-and-obstructive-sleep-apnea-in-acute-first-ever-ischemic-stroke
#15
Anna Losurdo, Valerio Brunetti, Aldobrando Broccolini, Pietro Caliandro, Giovanni Frisullo, Roberta Morosetti, Fabio Pilato, Paolo Profice, Nadia Mariagrazia Giannantoni, Maria Luisa Sacchetti, Elisa Testani, Catello Vollono, Giacomo Della Marca
BACKGROUND: Obstructive sleep apnea (OSA) and dysphagia are common in acute stroke and are both associated with increased risk of complications and worse prognosis. The aims of the present study were (1) to evaluate the prevalence of OSA and dysphagia in patients with acute, first-ever, ischemic stroke; (2) to investigate their clinical correlates; and (3) to verify if these conditions are associated in acute ischemic stroke. METHODS: We enrolled a cohort of 140 consecutive patients with acute-onset (<48 hours), first-ever ischemic stroke...
October 23, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29072062/morpho-functional-cardiovascular-adaptation-in-hypertensive-patients-two-dimensional-speckle-tracking-echocardiographic-study
#16
Ines P Monte, Chiara DI Benedetto, Filippo A Atanasio, Valentina Losi, Salvatore Licciardi, Corrado Tamburino
BACKGROUND: Twenty-four-hour Blood Pressure (BP) variability is an important predictor of organ damage and cardiovascular events. Although epidemiological data are widely based on evaluation of office (Clinic) BP, 24-hour Ambulatory BP monitoring (ABPM) accurately assess the severity of hypertension to predict cardiovascular events in hypertensive patients, because it more accurately reflects BP load on heart and blood vessels. Conventional transthoracic echocardiography (TTE), such as M-mode and two-dimensional (2D), and more advanced techniques, such as tissue Doppler imaging (TDI) and speckle tracking echocardiography (STE), are used to identify pathological changes of the hypertensive heart disease...
October 25, 2017: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/29072001/-randomized-controlled-clinical-trials-of-eye-acupuncture-therapy-for-patients-with-post-stroke-insomnia
#17
Lu-Yang Liu, Peng-Qin Wang
OBJECTIVE: To observe the therapeutic effect of eye-acupuncture therapy for post-stroke insomnia. METHODS: Sixty patients (45-70 years in age) with post-stroke insomnia were randomized into eye-acupuncture group and routine acupuncture (body acupuncture) group (30 cases in each). Patients of the eye-acupuncture group were treated by acupuncture stimulation of bilateral Shangjiao (Upper-energizer) and Xin (Heart) regions and those of the routine acupuncture group treated by acupuncture stimulation of Baihui (GV 20), Sishencong (EX-HN 1), Anmian (EX-HN 16), etc...
February 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29069399/a-meta-analysis-of-continuous-positive-airway-pressure-therapy-in-prevention-of-cardiovascular-events-in-patients-with-obstructive-sleep-apnoea
#18
Safi U Khan, Crystal A Duran, Hammad Rahman, Manidhar Lekkala, Muhammad A Saleem, Edo Kaluski
Aims: To assess whether continuous positive airway pressure (CPAP) therapy reduces major adverse cardiovascular events (MACE) in patients with moderate-to-severe obstructive sleep apnoea (OSA). Methods and results: A total of 235 articles were recovered using MEDLINE, EMBASE and Cochrane library (inception-December 2016) and references contained in the identified articles. Seven randomized controlled trials (RCTs) were selected for final analysis. Analysis of 4268 patients demonstrated non-significant 26% relative risk reduction in MACE with CPAP [risk ratio (RR) 0...
October 24, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29065961/nocturnal-desaturation-is-associated-with-neurological-deterioration-following-ischemic-stroke-a-retrospective-observational-study
#19
Tae Jung Kim, Sang-Bae Ko, Han-Gil Jeong, Chi Kyung Kim, Yerim Kim, Kiwoong Nam, Heejung Mo, Sang Joon An, H Alex Choi, Byung-Woo Yoon
STUDY OBJECTIVES: The mechanism of early neurological deterioration (END) in patients with stroke remains unclear. We assessed the relationship between nocturnal oxygen desaturation (NOD) in the stroke unit (SU) and END, especially occurring at nighttime, following acute stroke. METHODS: A retrospective analysis was performed on a total of 276 patients with ischemic stroke who were admitted to the SU between July 2013 and June 2015. The oxygen desaturation index was calculated from pulse oximetry data sampled every 1 minute during 9 hours on the first night (10:00 pm to 7:00 am) after admission, and NOD was defined as oxygen desaturation index ≥ 5 events/h...
October 18, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29065956/distinct-patterns-of-hyperpnea-during-cheyne-stokes-respiration-implication-for-cardiac-function-in-patients-with-heart-failure
#20
Elisa Perger, Toru Inami, Owen D Lyons, Hisham Alshaer, Stephanie Smith, John S Floras, Alexander G Logan, Michael Arzt, Joaquin Duran Cantolla, Diego Delgado, Michael Fitzpatrick, John Fleetham, Takatoshi Kasai, R John Kimoff, Richard S T Leung, Geraldo Lorenzi Filho, Pierre Mayer, Lisa Mielniczuk, Debra L Morrison, Gianfranco Parati, Sairam Parthasarathy, Stefania Redolfi, Clodagh M Ryan, Frederic Series, George A Tomlinson, Anna Woo, T Douglas Bradley
STUDY OBJECTIVES: In heart failure (HF), we observed two patterns of hyperpnea during Cheyne-Stokes respiration with central sleep apnea (CSR-CSA): a positive pattern where end-expiratory lung volume remains at or above functional residual capacity, and a negative pattern where it falls below functional residual capacity. We hypothesized the negative pattern is associated with worse HF. METHODS: Patients with HF underwent polysomnography. During CSR-CSA, hyperpnea, apnea-hyperpnea cycle, and lung to finger circulation times (LFCT) were measured...
October 18, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
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