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https://www.readbyqxmd.com/read/29780410/quantification-of-upper-limb-motor-recovery-and-eeg-power-changes-after-robot-assisted-bilateral-arm-training-in-chronic-stroke-patients-a-prospective-pilot-study
#1
Marialuisa Gandolfi, Emanuela Formaggio, Christian Geroin, Silvia Francesca Storti, Ilaria Boscolo Galazzo, Marta Bortolami, Leopold Saltuari, Alessandro Picelli, Andreas Waldner, Paolo Manganotti, Nicola Smania
Background: Bilateral arm training (BAT) has shown promise in expediting progress toward upper limb recovery in chronic stroke patients, but its neural correlates are poorly understood. Objective: To evaluate changes in upper limb function and EEG power after a robot-assisted BAT in chronic stroke patients. Methods: In a within-subject design, seven right-handed chronic stroke patients with upper limb paresis received 21 sessions (3 days/week) of the robot-assisted BAT...
2018: Neural Plasticity
https://www.readbyqxmd.com/read/29730541/stroke-causes-a-transient-imbalance-of-interhemispheric-information-flow-in-eeg-during-non-rem-sleep
#2
Frederic Zubler, Andrea Seiler, Thomas Horvath, Corinne Roth, Silvia Miano, Christian Rummel, Heidemarie Gast, Lino Nobili, Kaspar A Schindler, Claudio L Bassetti
OBJECTIVE: Large-scale connectivity, especially interhemispheric connections, plays a crucial role for recovery after stroke. Here we used methods from information theory to characterize interhemispheric information flow in wake- and sleep-EEG after cerebral ischemia. METHODS: 34 patients with unilateral ischemic stroke were included. Symbolic Transfer Entropy (STE) was applied between bipolar EEG signals on the left and the right cerebral hemisphere during polysomnographic recordings in the acute phase and 3 months after stroke...
April 17, 2018: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29724661/ifcn-endorsed-practical-guidelines-for-clinical-magnetoencephalography-meg
#3
REVIEW
Riitta Hari, Sylvain Baillet, Gareth Barnes, Richard Burgess, Nina Forss, Joachim Gross, Matti Hämäläinen, Ole Jensen, Ryusuke Kakigi, François Mauguière, Nobukatzu Nakasato, Aina Puce, Gian-Luca Romani, Alfons Schnitzler, Samu Taulu
Magnetoencephalography (MEG) records weak magnetic fields outside the human head and thereby provides millisecond-accurate information about neuronal currents supporting human brain function. MEG and electroencephalography (EEG) are closely related complementary methods and should be interpreted together whenever possible. This manuscript covers the basic physical and physiological principles of MEG and discusses the main aspects of state-of-the-art MEG data analysis. We provide guidelines for best practices of patient preparation, stimulus presentation, MEG data collection and analysis, as well as for MEG interpretation in routine clinical examinations...
April 17, 2018: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29695280/shaping-neuroplasticity-by-using-powered-exoskeletons-in-patients-with-stroke-a-randomized-clinical-trial
#4
Rocco Salvatore Calabrò, Antonino Naro, Margherita Russo, Placido Bramanti, Luigi Carioti, Tina Balletta, Antonio Buda, Alfredo Manuli, Serena Filoni, Alessia Bramanti
BACKGROUND: The use of neurorobotic devices may improve gait recovery by entraining specific brain plasticity mechanisms, which may be a key issue for successful rehabilitation using such approach. We assessed whether the wearable exoskeleton, Ekso™, could get higher gait performance than conventional overground gait training (OGT) in patients with hemiparesis due to stroke in a chronic phase, and foster the recovery of specific brain plasticity mechanisms. METHODS: We enrolled forty patients in a prospective, pre-post, randomized clinical study...
April 25, 2018: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/29614297/eeg-based-neglect-assessment-a-feasibility-study
#5
Aya Khalaf, Jessica Kersey, Safaa Eldeeb, Gazihan Alankus, Emily Grattan, Laura Waterstram, Elizabeth Skidmore, Murat Akcakaya
BACKGROUND: Spatial neglect (SN) is a neuropsychological syndrome that impairs automatic attention orienting to stimuli in the contralesional visual space of stroke patients. SN is commonly assessed using paper and pencil tests. Recently, computerized tests have been proposed to provide a dynamic assessment of SN. However, both paper- and computer-based methods have limitations. NEW METHOD: Electroencephalography (EEG) shows promise for overcoming the limitations of current assessment methods The aim of this work is to introduce an objective passive BCI system that records EEG signals in response to visual stimuli appearing in random locations on a screen with a dynamically changing background...
March 31, 2018: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/29602853/association-between-refill-adherence-to-lipid-lowering-medications-and-the-risk-of-cardiovascular-disease-and-mortality-in-swedish-patients-with-type-2-diabetes-mellitus-a-nationwide-cohort-study
#6
Sofia Axia Karlsson, Christel Hero, Ann-Marie Svensson, Stefan Franzén, Mervete Miftaraj, Soffia Gudbjörnsdottir, Katarina Eeg-Olofsson, Björn Eliasson, Karolina Andersson Sundell
OBJECTIVES: To analyse the association between refill adherence to lipid-lowering medications, and the risk of cardiovascular disease (CVD) and mortality in patients with type 2 diabetes mellitus. DESIGN: Cohort study. SETTING: National population-based cohort of Swedish patients with type 2 diabetes mellitus. PARTICIPANTS: 86 568 patients aged ≥18 years, registered with type 2 diabetes mellitus in the Swedish National Diabetes Register, who filled at least one prescription for lipid-lowering medication use during 2007-2010, 87% for primary prevention...
March 30, 2018: BMJ Open
https://www.readbyqxmd.com/read/29602053/eeg-findings-and-outcomes-of-continuous-video-eeg-monitoring-started-prior-to-initiation-of-seizure-treatment-in-the-perinatal-stroke
#7
José R Castro Conde, Itziar Quintero Fuentes, Candelaria González Campo, Alejandro Jiménez Sosa, Beatriz Reyes Millán, Sergio Hernández Expósito
BACKGROUND: To analyze the findings in the background EEG activity of infants who suffered perinatal stroke. METHODS: Eleven neonates born 2009-2014 diagnosed of ischemic stroke by MRI (three of them with multistroke) underwent continuous video-EEG monitoring. Visual and spectral (power spectrum and coherence) analyses of the background EEG was performed in three moments: 1) Onset of EEG recording (prior to initiate seizure treatment), 2) Post-ictal epoch (1-2 h after the last seizure), and 3) one-two days after seizure control...
March 27, 2018: Early Human Development
https://www.readbyqxmd.com/read/29588974/seizures-electroencephalographic-abnormalities-and-outcome-of-ischemic-stroke-patients
#8
Carla Bentes, Ana Rita Peralta, Hugo Martins, Carlos Casimiro, Carlos Morgado, Ana Catarina Franco, Pedro Viana, Ana Catarina Fonseca, Ruth Geraldes, Patrícia Canhão, Teresa Pinho E Melo, Teresa Paiva, José M Ferro
Objective: Seizures and electroencephalographic (EEG) abnormalities have been associated with unfavorable stroke functional outcome. However, this association may depend on clinical and imaging stroke severity. We set out to analyze whether epileptic seizures and early EEG abnormalities are predictors of stroke outcome after adjustment for age and clinical/imaging infarct severity. Methods: A prospective study was made on consecutive and previously independent acute stroke patients with a National Institutes of Health Stroke Scale (NIHSS) score ≥ 4 on admission and an acute anterior circulation ischemic lesion on brain imaging...
December 2017: Epilepsia Open
https://www.readbyqxmd.com/read/29588227/resting-state-functional-connectivity-predicts-the-ability-to-adapt-to-robot-mediated-force-fields
#9
Irene Faiman, Sara Pizzamiglio, Duncan L Turner
Motor deficits are common outcomes of neurological conditions such as stroke. In order to design personalised motor rehabilitation programmes such as robot-assisted therapy, it would be advantageous to predict how a patient might respond to such treatment. Spontaneous neural activity has been observed to predict differences in the ability to learn a new motor behaviour in both healthy and stroke populations. This study investigated whether spontaneous resting-state functional connectivity could predict the degree of motor adaptation of right (dominant) upper limb reaching in response to a robot-mediated force field...
March 24, 2018: NeuroImage
https://www.readbyqxmd.com/read/29580905/-management-of-epilepsia-in-older
#10
Agathe Alberti, Benjamin Thomas, Cécile Marchal
Epilepsy increases in frequency with age, above 60, with consequences in terms of independence. Stroke and dementia are the most frequent etiologies. Clinical diagnostic of epileptic seizure is challenging at this age, and a clinical algorithm is proposed. Sleep EEG during one hour seems to be the most useful exam. Interictal and critical discharges can be seen during sleep in dementia ; relation between hyperexcitability and evolution of cognition has to be precised in this pathology. In a therapeutical point of view, it is necessary to bear in mind the pharmacological consequences of aging, polytherapies, and the frequency of adverse events in this age group...
March 2018: La Presse Médicale
https://www.readbyqxmd.com/read/29564192/herpes-simplex-virus-encephalitis-atypical-presentation-as-a-right-middle-cerebral-artery-stroke
#11
Maria Shoaib, Jacqueline J Kraus, Muhammad T Khan
Herpes simplex virus encephalitis (HSVE) is a medical emergency associated with high mortality and morbidity. Definitive diagnosis is established by history, clinical examination, neuroimaging studies, supportive electroencephalogram (EEG) findings, and cerebrospinal fluid (CSF) analysis. We report a case of HSVE presenting as a stroke mimic in a 76-year-old female with a history of atrial fibrillation on warfarin. She was admitted to our medical intensive care unit with intermittent fever, lethargy, and new onset left-sided hemiparesis...
January 15, 2018: Curēus
https://www.readbyqxmd.com/read/29547472/clinical-and-electrographic-correlates-of-bilateral-independent-periodic-discharges
#12
Brin Freund, James J Gugger, Alexandra Reynolds, William O Tatum, Jan Claassen, Peter W Kaplan
PURPOSE: Periodic discharges (PDs) are EEG patterns denoting brain dysfunction and ictal tendency. Their exact meaning regarding etiology and outcomes is not well known. In particular, bilateral independent PDs (BIPDs) are poorly described. METHODS: We performed a retrospective, multicenter study evaluating neuroimaging, epileptic, clinical, and EEG correlates of BIPDs. RESULTS: Twenty-five patients studied with a mean Glasgow Coma Scale 6...
May 2018: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/29545211/ling-yang-gou-teng-decoction-prevents-vascular-dementia-through-inhibiting-oxidative-stress-induced-neurovascular-coupling-dysfunction
#13
Xin Zhao, Jinyu Liu, Shijun Yang, Dandan Song, Chen Wang, Chen Chen, Xiaoya Li, Qiuting Wang, Shasha Ge, Runmei Yang, Xiuhua Liu, Yulin Lin, Dayong Cai
ETHNOPHARMACOLOGICAL RELEVANCE: Vascular dementia (VaD) is the common cognitive disorder derived mainly from lacunar stroke (LS). The oxidative stress induced neurovascular coupling (NVC) dysfunction involves in the pathogenesis of VaD. Currently, there is no specific drug for VaD. Ling-Yang-Gou-Teng -Decoction (LG), a well-known traditional Chinese formula, has been used for preventing VaD in clinic. AIM OF THE STUDY: In this study, we aimed to investigate the underlying mechanism of LG on VaD in rats...
March 13, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29532955/electrophysiological-changes-in-poststroke-subjects-with-depressed-mood-a-quantitative-eeg-study
#14
REVIEW
Chunfang Wang, Yuanyuan Chen, Changcheng Sun, Ying Zhang, Dong Ming, Jingang Du
BACKGROUND: We aimed to explore the electrophysiological changes in poststroke subjects with depressed mood. METHODS: Resting-state electroencephalogram (EEG) signals of 16 electrodes in 35 poststroke depressed, 24 poststroke nondepressed, and 35 age-matched healthy control subjects were analyzed by means of spectral power analysis, a quantitative EEG measurement of different frequency bands. The relationship among depressed mood, functional status, lesion side, and poststroke time was assessed by using variance and Spearman correlation analysis...
March 13, 2018: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29515363/fast-recognition-of-bci-inefficient-users-using-physiological-features-from-eeg-signals-a-screening-study-of-stroke-patients
#15
Xiaokang Shu, Shugeng Chen, Lin Yao, Xinjun Sheng, Dingguo Zhang, Ning Jiang, Jie Jia, Xiangyang Zhu
Motor imagery (MI) based brain-computer interface (BCI) has been developed as an alternative therapy for stroke rehabilitation. However, experimental evidence demonstrates that a significant portion (10-50%) of subjects are BCI-inefficient users (accuracy less than 70%). Thus, predicting BCI performance prior to clinical BCI usage would facilitate the selection of suitable end-users and improve the efficiency of stroke rehabilitation. In the current study, we proposed two physiological variables, i.e., laterality index (LI) and cortical activation strength (CAS), to predict MI-BCI performance...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29510399/contralesional-brain-activity-in-acute-ischemic-stroke
#16
Ruud C Van Kaam, Michel J A M van Putten, Sarah E Vermeer, Jeannette Hofmeijer
BACKGROUND: The noninjured, contralateral hemisphere is increasingly acknowledged in the process of recovery from acute ischemic stroke. We estimated the value of conventional electroencephalography (EEG) recordings for identifying contralateral hemisphere involvement in relation to functional recovery. METHODS: We analyzed 2-min epochs from 21 electrode EEG registrations of 18 patients with acute hemispheric ischemic stroke and compared with 18 age-matched controls...
2018: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/29484389/mtor-is-involved-in-stroke-induced-seizures-and-the-anti-seizure-effect-of-mild-hypothermia
#17
Guo-Shuai Yang, Xiao-Yan Zhou, Xue-Fang An, Xuan-Jun Liu, Yan-Jun Zhang, Dan Yu
Stroke is considered an underlying etiology of the development of seizures. Stroke leads to glucose and oxygen deficiency in neurons, resulting in brain dysfunction and injury. Mild hypothermia is a therapeutic strategy to inhibit stroke‑induced seizures, which may be associated with the regulation of energy metabolism of the brain. Mammalian target of rapamycin (mTOR) signaling and solute carrier family 2, facilitated glucose transporter member (GLUT)‑1 are critical for energy metabolism. Furthermore, mTOR overactivation and GLUT‑1 deficiency are associated with genetically acquired seizures...
April 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29481376/neural-decoding-of-robot-assisted-gait-during-rehabilitation-after-stroke
#18
Jose L Contreras-Vidal, Magdo Bortole, Fangshi Zhu, Kevin Nathan, Anusha Venkatakrishnan, Gerard E Francisco, Rogelio Soto, Jose L Pons
OBJECTIVE: Advancements in robot-assisted gait rehabilitation and brain-machine interfaces (BMI) may enhance stroke physiotherapy by engaging patients while providing information about robot-induced cortical adaptations. We investigate the feasibility of decoding walking from brain activity in stroke survivors during therapy using a powered exoskeleton integrated with an electroencephalography (EEG)-based BMI. DESIGN: The H2 powered exoskeleton was designed for overground gait training with actuated hip, knee and ankle joints...
February 23, 2018: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/29472849/eeg-based-brain-computer-interfaces-for-communication-and-rehabilitation-of-people-with-motor-impairment-a-novel-approach-of-the-21-st-century
#19
REVIEW
Ioulietta Lazarou, Spiros Nikolopoulos, Panagiotis C Petrantonakis, Ioannis Kompatsiaris, Magda Tsolaki
People with severe neurological impairments face many challenges in sensorimotor functions and communication with the environment; therefore they have increased demand for advanced, adaptive and personalized rehabilitation. During the last several decades, numerous studies have developed brain-computer interfaces (BCIs) with the goals ranging from providing means of communication to functional rehabilitation. Here we review the research on non-invasive, electroencephalography (EEG)-based BCI systems for communication and rehabilitation...
2018: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29465895/-clinical-neurophysiological-methods-in-diagnosis-and-treatment-of-cerebrovascular-diseases
#20
REVIEW
Ildikó Nagy, Dániel Fabó
Neurophysiological methods are gaining ground in the diagnosis and therapy of cerebrovascular disease. While the role of the EEG (electroencephalography) in the diagnosis of post-stroke epilepsy is constant, quantitative EEG para-meters, as new indicators of early efficiency after thrombolysis or in prognosis of patient's condition have proved their effectiveness in several clinical studies. In intensive care units, continuous EEG monitoring of critically ill patients became part of neurointenzive care protocols...
January 30, 2018: Ideggyógyászati Szemle
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