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https://www.readbyqxmd.com/read/28525446/training-village-health-workers-in-detection-and-monitoring-of-noncommunicable-diseases-a-low-cost-option-for-rural-areas-facing-the-emerging-health-epidemic
#1
Shyamsundar J Raithatha, Dinesh Kumar, Amee A Amin
Noncommunicable diseases account for 53% of deaths and 44% of disability-adjusted life years lost in India. Village health workers (VHWs) were trained in blood pressure (BP) and blood sugar (BS) measurement and assessed using a checklist. A total of 38 VHWs with a mean age of 44.8 years, schooling of 9.9 years, scored 10.0 (76.9%) for BP and 9.74 (69.6%) for BS. There was no difference in scores for education and age. It is possible to train VHWs in BP and BS measurement and utilize them for screening and monitoring of hypertension and diabetes in a noncommunicable disease care program...
July 2017: Family & Community Health
https://www.readbyqxmd.com/read/28523846/a-novel-rapid-analysis-using-mass-spectrometry-to-evaluate-downstream-refolding-of-recombinant-human-insulin-like-growth-factor-1-mecasermin
#2
Kenichiro Furuki, Toshimasa Toyo'oka, Hideto Yamaguchi
RATIONALE: Mecasermin is used to treat elevated blood sugar as well as growth hormone-resistant Laron-type dwarfism. Mecasermin isolated from inclusion bodies in extracts of E.coli must be refolded to acquire sufficient activity. However, there is no rapid analytical method for monitoring refolding during the purification process. METHODS: We prepared mecasermin drug product, in-process samples during the oxidation of mecasermin, forced-reduced mecasermin, and aerially oxidized mecasermin after forced reduction...
May 19, 2017: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/28521980/sulphated-polysaccharide-isolated-from-sargassum-vulgare-characterization-and-hypolipidemic-effects
#3
Rihab Ben Abdallah Kolsi, Hichem Ben Salah, Neila Jardak, Rim Chaaben, Imed Jribi, Abdelfattah El Feki, Tarak Rebai, Kamel Jamoussi, Noureddine Allouche, Cristophe Blecker, Hafedh Belghith, Karima Belghith
A sulphated polysaccharide from brown algae Sargassum vulgare (SVSP) was extracted and examined with respect to chemical, structural characterization and hypolipidemic effects. SVSP consisted mainly of sulphate and total sugars with low levels of lipids and proteins. Its structure was studied by nuclear magnetic resonance (RMN), gas chromatography-mass spectrometry (GC-MS), infra-red spectroscopic, differential scanning calorimetry and X-ray diffraction analysis. Allowing us therefore to revealed that SVSP was composed of glucose, rhamnose, xylose, galactose, mannose and arabinose with XRD pattern that was typical for a semi-crystalline polymer and complexities of the spectra reflected its homogeneous structure...
August 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28521737/validation-of-the-german-version-of-the-mediterranean-diet-adherence-screener-medas-questionnaire
#4
Katrin Hebestreit, Maryam Yahiaoui-Doktor, Christoph Engel, Walter Vetter, Michael Siniatchkin, Nicole Erickson, Martin Halle, Marion Kiechle, Stephan C Bischoff
BACKGROUND: Health benefits of the Mediterranean Diet (MD) have been shown in different at-risk populations. A German translation of the Mediterranean Diet Adherence Screener (MEDAS) from the PREvención con DIeta MEDiterránea (PREDIMED) consortium was used in the LIBRE study, investigating effects of lifestyle-intervention on women with BRCA1/2 mutations. The purpose of the present study is to validate the MEDAS German version. METHODS: LIBRE is a multicentre (three university hospitals during this pilot phase), unblinded, randomized, controlled clinical trial...
May 18, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28520705/disparities-in-diabetes-deaths-among-children-and-adolescents-united-states-2000-2014
#5
Sharon Saydah, Giuseppina Imperatore, Yiling Cheng, Linda S Geiss, Ann Albright
Diabetes is a common chronic disease of childhood affecting approximately 200,000 children and adolescents in the United States (1). Children and adolescents with diabetes are at increased risk for death from acute complications of diabetes, including hypoglycemia and diabetic ketoacidosis (2,3); in 2012, CDC reported that during 1968-2009, diabetes mortality among U.S. persons aged ≤19 years declined by 61% (4). CDC observed disparities by race during 1979-2004, with black children and adolescents dying from diabetes at twice the rate of white children and adolescents (5)...
May 19, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28520550/outcomes-that-matter-to-teens-with-type-1-diabetes
#6
Clara Y Ye, Thor C Jeppson, Ellen M Kleinmaus, Harald M Kliems, Jennifer M Schopp, Elizabeth D Cox
Purpose The purpose of the study was to describe outcomes that matter to teens with type 1 diabetes. Understanding outcomes that matter to teens could support successful interventions to improve diabetes self-management. Methods Fifty publicly available posts published in the "teen" sections of 2 major diabetes online forums between 2011 and 2013 were analyzed using qualitative research methods. From each post, content and descriptive data (eg, duration of diabetes and age) were collected. Two members of the research team independently used open coding techniques to identify outcomes (defined as impacts or consequences of type 1 diabetes) and organized them into themes and subthemes...
June 2017: Diabetes Educator
https://www.readbyqxmd.com/read/28516404/screening-for-diabetic-eye-disease-among-samoan-adults-a-pilot-study
#7
V Swetha E Jeganathan, Tim Langford, Lucilla Ah-Ching Sefo, Alex W Hewitt, Nitin Verma
INTRODUCTION: The purpose of this study was to determine the prevalence of diabetic retinopathy in Samoa by piloting a retinal photography screening programme. METHODS: We performed a cross-sectional study of patients with diabetes who presented to the Tupua Tamasese Meaole eye clinic in Apia, Samoa, between May 2011 and September 2011. Study approval was granted by the National Health Service Board of Samoa, the Monash University Human Research Ethics Committee, and the study adhered to the Tenets of the Declaration of Helsinki...
May 17, 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28511436/glycaemic-and-insulin-response-to-equi-quantity-of-selected-common-indian-staples-in-individuals-with-type-2-diabetes-mellitus
#8
Neha V Paharia, Kasturi Sen Ray
INTRODUCTION: Diet therapy is one of the corner stone's in the management of diabetes. Keeping the blood sugar level as close to normal is the main focus of dietary management of diabetes. A typical Indian meal is largely composed of Carbohydrates (CHO). Consumption of staple cereals, forms the major source of CHO in the Indian diet. However, CHO metabolism is seen to be completely deranged in a person with type 2 diabetes. It is necessary to select the cereal which has lower postprandial glycaemic impact for subjects with compromised metabolic status...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28511371/study-of-serum-total-psa-and-free-psa-as-an-oncological-marker-in-breast-tumour
#9
Elteza Tahjiba Jahir, Runi Devi, Bibhuti Bhushan Borthakur
INTRODUCTION: Breast Cancer (BC) cases are rising alarmingly all over the world and India is not an exception. This rising trend is due to an increased age at first child birth, decreased breast feeding, and the changing lifestyle mostly in urban India. With the advent of more sensitive methodologies and research works in this field, it has been suggested that Prostate Specific Antigen (PSA) plays an important role in the pathogenesis of breast cancer besides other established tumour markers...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28510998/new-onset-type-2-diabetes-mellitus-among-patients-receiving-hiv-care-at-newlands-clinic-harare-zimbabwe-retrospective-cohort-analysis
#10
Cleophas Chimbetete, Catrina Mugglin, Tinei Shamu, Bindu Kalesan, Barbara Bertisch, Matthias Egger, Olivia Keiser
OBJECTIVE: To assess the incidence and associated factors of Type 2 Diabetes Mellitus (T2DM) among people living with HIV (PLHIV) in Zimbabwe. METHODS: We analyzed data of all HIV-infected patients older than 16 years who attended Newlands Clinic between March 1, 2004 and April 29, 2015. The clinic considers patients whose random blood sugar is higher than 11.1 mmol/L and which is confirmed by a fasting blood sugar higher than 7.0 mmol/L to have T2DM. T2DM is also diagnosed in symptomatic patients who have a RBS >11...
May 16, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28509874/evaluation-of-the-mycobactericidal-effect-of-thio-functionalized-carbohydrate-derivatives
#11
Małgorzata Korycka-Machała, Anna Brzostek, Bożena Dziadek, Malwina Kawka, Tomasz Popławski, Zbigniew J Witczak, Jarosław Dziadek
Sugars with heteroatoms other than oxygen have attained considerable importance in glycobiology and in drug design since they are often more stable in blood plasma due to their resistance to enzymes, such as glycosidases, phosphorylases and glycosyltransferases. The replacement of oxygen atoms in sugars with sulfur forms thio-sugars, which are potentially useful for the treatment of diabetes and some bacterial and viral infections. Here, we evaluated the antibacterial activity of thio-functionalized carbohydrate derivatives...
May 16, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28508651/sugar-breathing-glycopolymersomes-for-regulating-glucose-level
#12
Yufen Xiao, Hui Sun, Jianzhong Du
Diabetes mellitus is a chronic, life-threatening illness that affects people of every age and ethnicity. It is a long-suffering pain for those who are affected and must regulate their blood glucose level by frequent subcutaneous injection of insulin every day. Herein, we propose a non-insulin and antidiabetic-drug-free strategy for regulating blood glucose level by a nano-sized "sugar sponge" which is a lectin-bound glycopolymersome capable of regulating glucose due to the dynamic recognition between the lectin and different carbohydrates...
May 16, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28507727/correlation-between-hemoglobin-a1c-and-serum-lipid-profile-in-afghani-patients-with-type-2-diabetes-hemoglobin-a1c-prognosticates-dyslipidemia
#13
Arshad Hussain, Iftikhar Ali, Muhammad Ijaz, Afaq Rahim
BACKGROUND: Patients with type 2 diabetes (T2DM) have an increased prevalence of dyslipidemia, which contributes to their high risk of cardiovascular diseases (CVDs). This study is an attempt to determine the correlation between hemoglobin A1c (HbA1c) and serum lipid profile and to evaluate the importance of HbA1c as an indicator of dyslipidemia in Afghani patients with T2DM. METHODS: A total of 401 Afghani patients with T2DM (men, 175; women, 226; mean age, 51...
April 2017: Therapeutic Advances in Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28507406/evaluation-of-different-agroindustrial-waste-on-the-effect-of-different-carcass-characteristics-and-physiological-and-biochemical-parameters-in-broilers-chicken
#14
Y Sánchez-Roque, Y D C Pérez-Luna, E Pérez-Luna, R Berrones Hernández, S Saldaña-Trinidad
AIM: This study was conducted to evaluate the physiological and biochemical effect in chickens of the Ross breed of a food enriched with agroindustrial waste. MATERIALS AND METHODS: The food is one of the main components of the total cost for the production of chickens. Rations should be formulated to provide the correct balance of energy, protein, amino acids, minerals, vitamins and essential fatty acids, to allow optimal growth and performance. This study was intended to evaluate a natural feed for chicken, made from corn, yucca meal, eggshells, orange peel, soybean meal, salt and garlic, enriched with agroindustrial waste (molasses, milk whey and ferment of coffee)...
April 2017: Veterinary World
https://www.readbyqxmd.com/read/28507365/frequency-and-predictors-of-metabolic-syndrome-in-adolescents-first-year-medical-students-of-a-public-sector-medical-college-quetta-pakistan
#15
Faisal Shahzad, Aiesha Ishaque
Objective: To determine the prevalence of metabolic syndrome in medical students. METHODS: This cross-sectional study was conducted at the Bolan Medical College, Quetta, Pakistan, from August 2015 to January 2016, and comprised healthy first-year medical students. Demographic data was assessed using a self-administered questionnaire. Height, weight and waist circumference were measured along with fasting blood sugar, high-density lipoprotein and triglycerides by using automated biochemistry analyser...
May 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28507358/effect-of-citrullus-colocynthis-aqueous-seed-extract-on-beta-cell-regeneration-and-intra-islet-vasculature-in-alloxan-induced-diabetic-male-albino-rats
#16
Alia Amin, Mohammad Tahir, Khalid Pervez Lone
OBJECTIVE: To observe the effect of Citrullus colocynthis on beta cell regeneration and intra-islet vasculature. METHODS: This experimental study was conducted at the University of Health Sciences, Lahore, Pakistan, from February 2013 to January 2014. It comprised male wistar rats weighing 100-150gand aged 6-8 weeks. The animals were divided into 6 groups. Group A1 served as control. Diabetes was induced in groups A2, B2 and C2 using single intravenous injection of 50mg/kg of alloxan...
May 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28504654/sugar-makes-neutrophils-rage-linking-diabetes-associated-hyperglycemia-to-thrombocytosis-and-platelet-reactivity
#17
Robert H Lee, Wolfgang Bergmeier
Diabetes mellitus is associated with an increased risk for cardiovascular disease, but the link between hyperglycemia and atherothrombotic disease is not completely understood. Patients with diabetes often show hyporesponsiveness to antiplatelet therapies, and it has been suggested that hyperreactive reticulated platelets underlie this altered therapeutic response. In this issue of the JCI, Kraakman et al. uncover a previously unknown link between hyperglycemia and enhanced platelet production and reactivity...
May 15, 2017: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28503791/blood-glucose-and-insulin-concentrations-after-octreotide-administration-in-horses-with-insulin-dysregulation
#18
N Frank, P Hermida, A Sanchez-Londoño, R Singh, C M Gradil, C K Uricchio
BACKGROUND: Octreotide is a somatostatin analog that suppresses insulin secretion. HYPOTHESIS: We hypothesized that octreotide would suppress insulin concentrations in horses and that normal (N) horses and those with insulin dysregulation (ID) would differ significantly in their plasma glucose and insulin responses to administration of octreotide. ANIMALS: Twelve horses, N = 5, ID = 7. METHODS: Prospective study. An oral sugar test was performed to assign horses to N and ID groups...
May 15, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28503281/effect-of-septimeb-tm-as-a-new-natural-extract-on-severe-sepsis-a-randomized-clinical-trial
#19
Alieh Pourdast, Maryam Sanaei, Sirous Jafari, Mostafa Mohammadi, Hossein Khalili, Gita Shafiee, Zeinab Ahadi, Mahsa Rostami, Saba Alizad, Ramin Heshmat, Minoo Mohraz
BACKGROUND: Septimeb as a herbal medicine has regulatory effects on inflammation. This study set to evaluate the effects of Septimeb among patients with sepsis on inflammatory biomarkers and survival rate. METHODS: In this randomized clinical trial, 51 patients with sepsis from the ICU and medical ward of Imam Khomeini Hospital were divided into two groups: Septimeb (n=25) and control group (n=26). In the control group, the patients received a standard treatment only for 7 days, while Septimeb group received Septimeb (6cc vial with 500cc serum glucose infusion 5% daily for one to two hours) plus standard treatment of sepsis for 7 days...
2017: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/28502385/the-effects-of-blood-glucose-regulation-on-tear-function-tests-in-diabetic-patients
#20
S Kan, U Acar, M Kizilgul, E Beyazyildiz, A B Cankaya, O Ozcelik, M Ozbek
PURPOSE: To investigate whether blood glucose regulation in patients with diabetes mellitus (DM) has an influence on the ocular surface disease index (OSDI) score and tear function tests such as tear film osmolarity (TFO), tear break-up time (TBUT) and Schirmer tests. METHODS: Fifty diabetic patients with a fasting blood glucose (FBG) level greater than 200mg/dL and HbA1c level greater than 10% were recruited for this prospective study. All of the patients underwent a detailed ophthalmic examination including OSDI questionnaire, TFO test, TBUT test and Schirmer test initially...
May 11, 2017: Journal Français D'ophtalmologie
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