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https://www.readbyqxmd.com/read/28546050/shared-decision-making-in-argentina-in-2017
#1
Mariela Barani, Karin Kopitowski, Carolina Carrara, María Victoria Ruiz Yanzi
Argentina is a high-middle income country located in Southern South America with an estimated population of 44 million inhabitants. The epidemiological profile of the population is characterised by an increase of non-communicable diseases. The health system is heterogeneous, fragmented and loosely integrated. There are no unified research agenda or government initiatives encouraging the implementation of and research on Shared Decision-Making (SDM). Progress has been made lately to respect patient autonomy through the enactment of the 'Patients' Rights Act', which expressly enshrines the right of patients to get information as a key element of decision-making...
May 22, 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/28541690/bioactive-glycosides-from-the-twigs-of-litsea-cubeba
#2
Ling-Yan Wang, Ming-Hua Chen, Jiang Wu, Hua Sun, Wei Liu, Yu-Hong Qu, Yan-Cheng Li, Yu-Zhuo Wu, Rui Li, Dan Zhang, Su-Juan Wang, Sheng Lin
The air-dried twigs of Litsea cubeba, a traditional Chinese medicinal tree, afforded 10 new aromatic glycosides (1-10) and 26 known analogues. Their structures were assigned by extensive 1D and 2D NMR experiments, and the absolute configurations were resolved by chemical methods, electronic circular dichroism, specific rotation, and X-ray crystallographic analysis. Compound 4 is the first example of a naturally occurring homoneolignan glucoside. Compounds 4, 6-8, and the known neolignan glucosides (11, 12, and 14) at respective 10 μM concentrations were found to reduce acetaminophen-induced HepG2 cell injury with 30...
May 25, 2017: Journal of Natural Products
https://www.readbyqxmd.com/read/28540549/the-association-between-air-pollutants-and-autism-spectrum-disorders
#3
Chunyan Yang, Weiwei Zhao, Kui Deng, Vanessa Zhou, Xiaohua Zhou, Yan Hou
Autism spectrum disorders are a member of the pervasive developmental disorders (PDDs) that have been increasing dramatically since described by Leo Kanner in 1943. In the past decade, the number of epidemiological publications addressing air pollution exposures and autism has grown correspondingly, but the association is still unclear. Whether air pollutants play a causal role and which substances are related with autism requires further study. We systematically reviewed the literature from 2005 to 2016 in MEDLINE (National Library of Medicine), Web of Science, and PubMed and summarized the association between different air pollutants and autism...
May 24, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28539723/antimicrobial-and-anti-inflammatory-effects-of-ethanol-extract-of-corylopsis-coreana-uyeki-flos
#4
Da-Eon Park, In-Soo Yoon, Jung-Eun Kim, Ji-Hye Seo, Jin-Cheol Yoo, Chun-Sik Bae, Chang-Dai Lee, Dae-Hun Park, Seung-Sik Cho
BACKGROUND: Corylopsis coreana Uyeki (Hamamelidaceae) is a medicinal plant cultivated in Northeast Asia. Previously, we have reported that an ethanol extract of Corylopsis coreana Uyeki flos (ECCF) contains four active compounds with antioxidant activity. OBJECTIVE: The aim of this study was to investigate the antimicrobial spectrum against infectious bacteria and anti-inflammatory effect of ECCF in a mouse model of acute local inflammation. MATERIALS AND METHODS: In vitro antimicrobial susceptibility was evaluated using standard plate assay technique...
April 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28534147/hypothyroidism-in-hospitalized-elderly-patients-a-sign-of-worse-prognosis
#5
N Sforza, J Rosenfarb, R Rujelman, M Rosmarin, E Blanc, C Frigerio, P Fossati, D Caruso, C Faingold, T Meroño, G Brenta
PURPOSE: Overt hypothyroidism has adverse clinical consequences and might worsen prognosis in critically ill elderly patients. However, the difficult interpretation of thyroid function tests (TFT) due to non-thyroidal illness (NTI) has led to discouragement of screening for thyroid dysfunction. Our aim was to determine the prevalence of TFT compatible with hypothyroidism and to study its influence on mortality among hospitalized elderly patients. METHODS: In this prospective study we consecutively included all patients ≥60 years admitted by the Internal Medicine Department to the hospital ward (n = 451) of the Cesar Milstein Hospital in Buenos Aires, Argentina...
May 22, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28531789/do-picu-patients-meet-technical-criteria-for-performing-indirect-calorimetry
#6
Megan R Beggs, Gonzalo Garcia Guerra, Bodil M K Larsen
BACKGROUND & AIMS: Indirect calorimetry (IC) is considered gold standard for assessing energy needs of critically ill children as predictive equations and clinical status indicators are often unreliable. Accurate assessment of energy requirements in this vulnerable population is essential given the high risk of over or underfeeding and the consequences thereof. The proportion of patients and patient days in pediatric intensive care (PICU) for which energy expenditure (EE) can be measured using IC is currently unknown...
October 2016: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28529304/sebastian-kneipp-and-the-natural-cure-movement-of-germany-between-naturalism-and-modern-medicine
#7
Youkyung Ko
This study discusses the historical significance of the Natural Cure Movement of Germany, centering on the Kneipp Cure, a form of hydrotherapy practiced by Father Sebastian Kneipp (1821-1897). The Kneipp Cure rested on five main tenets: hydrotherapy, exercise, nutrition, herbalism, and the balance of mind and body. This study illuminates the reception of the Kneipp Cure in the context of the trilateral relationship among the Kneipp Cure, the Natural Cure Movement in general, and modern medicine. The Natural Cure Movement was ideologically based on naturalism, criticizing industrialization and urbanization...
December 2016: Ŭi Sahak
https://www.readbyqxmd.com/read/28524747/health-care-students-at-an-argentinean-school-of-medicine-are-they-well-prepared-to-provide-quality-sexual-and-reproductive-health-services
#8
Belén Provenzano-Castro, Silvia Oizerovich, Babill Stray-Pedersen
OBJECTIVES: The aim of our study was to assess what students of the University of Buenos Aires School of Medicine learn about sexual and reproductive health (SRH) and rights, focusing particularly on their knowledge of accessibility to contraception and abortion legislation. METHODS: In this cross-sectional study, self-administered, anonymous questionnaires were administered to 760 first year students and to 695 final year students from different fields of study (medicine, midwifery, nursing, radiology, nutrition, speech therapy and physiotherapy) between 2011 and 2013...
May 19, 2017: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/28516258/-biomarkers-of-internal-exposure-to-toxicologically-relevant-contaminants-in-food
#9
REVIEW
Klaus Abraham, Bernhard Monien, Alfonso Lampen
The assessment of health risks resulting from the intake of genotoxic carcinogens in food depends essentially on a valid exposure assessment. The reliability of the external exposure estimation is restricted by various factors, e. g. inaccurate data from dietary protocols and variations of food contaminant contents. As an alternative, the individual internal exposure to genotoxic substances may be described by specific biomarkers in different matrices. For example, mercapturic acids formed after glutathione conjugation of electrophilic metabolites can be detected in the urine...
May 17, 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/28512601/anti-nociceptive-and-anti-inflammatory-potentials-of-vernoniaamygdalina-leaf-extract-via-reductions-of-leucocyte-migration-and-lipid-peroxidation
#10
Samuel Adetunji Onasanwo, Oyetola Tolulope Oyebanjo, Abayomi Mayowa Ajayi, Mujeedat Adebukola Olubori
BACKGROUND: Vernonia amygdalina is well known as a medicinal plant in folk medicine as antidiabetic, anthelmintic, antimalarial, laxative/purgative, and expectorant among others. AIM: This study was conducted to investigate the antinociceptive and anti-inflammatory effects of V. amygdalina. MATERIALS AND METHODS: Methanol extract of V. amygdalina leaf (MEVA) was evaluated for antinociceptive effect and possible mechanisms of action in the presence of naloxone (1 mg/kg), atropine (2 mg/kg), and prazosin (1 mg/kg) using acetic acid writhing test in mice...
April 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28509774/the-role-of-the-anaesthesiologist-in-air-ambulance-medicine
#11
Stephen J M Sollid, Marius Rehn
PURPOSE OF REVIEW: The care administered on air ambulances has become increasing complex. This has led to a discussion among experts as to whether air ambulance travel should be manned by physicians. This review provides evidence in support of anaesthesiologists being the physician-leaders in air ambulance medicine, because of their training in advanced airway management, critical care, and resuscitation. RECENT FINDINGS: Successful prehospital care requires the ability to perform a complex set of advanced diagnostics and interventions...
May 13, 2017: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/28505393/the-science-behind-one-health-at-the-interface-of-humans-animals-and-the-environment
#12
Michael P Murtaugh, Clifford J Steer, Srinand Sreevatsan, Ned Patterson, Shaun Kennedy, P Sriramarao
Humans face a grand quality-of-life challenge as growing demands for resources for an ever-expanding population threaten the existence of wildlife populations, degrade land, and pollute air and water. Public investment and policy decisions that will shape future interactions of humans, animals, and the environment need scientific input to help find common ground for durable and sustainable success. The Second International Conference on One Medicine One Science brought together a broad range of scientists, trainees, regulatory authorities, and health experts from 34 countries to inform and discuss the human impacts of air quality; the complexities of water quality, access, and conflicts; the opportunities and uncertainties in precision medicine; and the role of science communication in health policy formulation...
May 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/28503417/indoor-outdoor-not-voluptuary-habit-pollution-and-sleep-disordered-breathing-in-children-a-systematic-review
#13
Laura Tenero, Giorgio Piacentini, Luana Nosetti, Emma Gasperi, Michele Piazza, Marco Zaffanello
BACKGROUND: Exposure to environmental pollutants is advocated to be a major risk factor, with increased morbidity and mortality in humans due to acute and chronic airway inflammation. The aim of the present review is to show the literature research regarding the link between the sleep-disordered breathing and exposure to indoor/outdoor pollution in children. We hypothesized that environmental air pollution can play a role in childhood sleep-disordered breathing. METHODS: We conducted an electronic search in Medline (with PubMed interface), Scopus and the ISI Web of Science using the keywords "sleep" or "sleep apnea" or "sleep disordered breathing" and "pollution" and "children" in "Title/Abstract/Keywords", with language restriction (non-English paper) and no date limitation to present...
April 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28502428/non-proximate-mass-spectrometry-using-a-heated-1-m-long-ptfe-tube-and-an-air-tight-apci-ion-source
#14
Dilshadbek T Usmanov, Kenzo Hiraoka, Hiroshi Wada, Masaya Matsumura, Sachiyo Sanada-Morimura, Hiroshi Nonami, Shinichi Yamabe
Direct and rapid trace-level gas analysis is highly needed in various fields such as safety and security, quality control, food analysis, and forensic medicine. In many cases, the real samples are bulky and are not accessible to the space-limited ion source of the mass spectrometer. In order to circumvent this problem, we developed an airtight atmospheric-pressure chemical ionization (APCI) ion source equipped with a flexible 1-m-long, 2-mm-i.d. PTFE sniffing tube. The ambient air bearing sample gas was sucked into the heated PTFE tube (130 °C) and was transported to the air-tight ion source without using any extra pumping system or a Venturi device...
June 22, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28495845/edmund-goodwyn-and-the-first-description-of-diving-bradycardia
#15
Jose L Vega
Diving bradycardia is a primordial oxygen-conserving reflex by which the heart rate of air-breathing vertebrates, including humans, slows down in response to water immersion. Its discovery is attributed to Paul Bert whose seminal observation was published in 1870 as part of a series of experiments that examined physiological adaptations to asphyxia in ducks and other animals. However, Edmund Goodwyn, a British physician who studied medicine at the University of Edinburgh had already published descriptions of this reflex in his doctoral thesis, which was originally published in Latin in 1786, and again in English in 1788...
May 11, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28494303/hemocompatibility-of-inhaled-environmental-nanoparticles-potential-use-of-in-vitro-testing
#16
REVIEW
Eleonore Fröhlich
Hemocompatibility testing is an important part in the evaluation of nano-based medicines. However, it is not systematically used for the assessment of environmental particles since they do not come in contact with blood immediately. Studies on human exposure to air-borne particles and pulmonary exposure of rodents have reported alterations in blood physiology. It is not clear, whether these effects are majorly caused by tissue inflammation or translocated particles in blood. This review addresses the question, if in vitro hemocompatibility testing could help in the risk evaluation of inhaled particles...
April 27, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28486083/progress-in-mass-spectrometry-based-proteomics-in-hypoxia-related-diseases-and-high-altitude-medicine
#17
Zhiqi Gao, Gang Luo, Bing Ni
Human migration, influenced by social conflict and natural disasters as well as global climate change, has become recognized as a major "planetary force." It has also brought to the forefront, new specialties of integrative biology-such as high-altitude medicine-and the impact of hitherto understudied environmental factors on human pathophysiology in these new geographical settings. For people migrating to or living in high-altitude regions, environmental hypoxia is a primary challenge. Decreased partial pressure of oxygen in environmental air, caused by lower barometric pressure, puts living organisms in a hypoxic state...
May 9, 2017: Omics: a Journal of Integrative Biology
https://www.readbyqxmd.com/read/28481316/phytochemical-profiles-and-antimicrobial-activities-of-allium-cepa-red-cv-and-a-sativum-subjected-to-different-drying-methods-a-comparative-ms-based-metabolomics
#18
Mohamed A Farag, Sara E Ali, Rashad H Hodaya, Hesham R El-Seedi, Haider N Sultani, Annegret Laub, Tarek F Eissa, Fouad O F Abou-Zaid, Ludger A Wessjohann
Plants of the Allium genus produce sulphur compounds that give them a characteristic (alliaceous) flavour and mediate for their medicinal use. In this study, the chemical composition and antimicrobial properties of Allium cepa red cv. and A. sativum in the context of three different drying processes were assessed using metabolomics. Bulbs were dried using either microwave, air drying, or freeze drying and further subjected to chemical analysis of their composition of volatile and non-volatile metabolites. Volatiles were collected using solid phase micro-extraction (SPME) coupled to gas chromatography-mass spectrometry (GC/MS) with 42 identified volatiles including 30 sulphur compounds, four nitriles, three aromatics, and three esters...
May 8, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28474553/metal-complex-peptide-conjugates-how-to-modulate-bioactivity-of-metal-containing-compounds-by-the-attachment-to-peptides
#19
Ines Neundorf
During the last years the interest in combining the features of metal-containing molecules with biomolecules, particularly peptides, has more and more increased. Large series of new innovative organometallic compounds, as well as potent coordination complexes have been designed and, especially in medicinal chemistry, the library of bioactive compounds was excessively expanded by the introduction of metal complexes. The research foci are divers and not limited to e.g. the development of therapeutics with anti-proliferative or antibacterial activity, or the design of novel biosensors useful for pharmaceutical applications...
May 4, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28468295/chemical-comparison-of-two-drying-methods-of-mountain-cultivated-ginseng-by-uplc-qtof-ms-ms-and-multivariate-statistical-analysis
#20
Xin-Fang Xu, Shu-Ya Xu, Ying Zhang, Hui Zhang, Meng-Nan Liu, Huan Liu, Yan Gao, Xue Xue, Hui Xiong, Rui-Chao Lin, Xiang-Ri Li
In traditional Chinese medicine practice, drying method is an essential factor to influence the components of Chinese medicinal herbs. In this study, an ultra-performance liquid chromatography quadrupole time-of-flight tandem mass spectrometry (UPLC-QTOF-MS/MS)-based approach was used to compare the content of chemical compounds of mountain cultivated ginseng that had been natural air dried (LX-P) and vacuum freeze-dried (LX-L). Multivariate statistical analysis such as principal component analysis (PCA) and supervised orthogonal partial least squared discrimination analysis (OPLS-DA) were used to select the influential components of different samples...
April 30, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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