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Cognitive Assessment System

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https://www.readbyqxmd.com/read/29924477/system-neuroscience-past-present-and-future
#1
REVIEW
Giacomo Rizzolatti, Maddalena Fabbri-Destro, Fausto Caruana, Pietro Avanzini
In this review, we discuss first the anatomical and lesion studies that allowed the localization of fundamental functions in the cerebral cortex of primates including humans. Subsequently, we argue that the years from the end of the Second World War until the end of the last century represented the "golden age" of system neuroscience. In this period, the mechanisms-not only the localization-underlying sensory, and in particular visual functions were described, followed by those underlying cognitive functions and housed in temporal, parietal, and premotor areas...
June 20, 2018: CNS Neuroscience & Therapeutics
https://www.readbyqxmd.com/read/29923471/validity-of-a-novel-computerized-screening-test-system-for-mild-cognitive-impairment
#2
Jin-Hyuck Park, Minye Jung, Jongbae Kim, Hae Yean Park, Jung-Ran Kim, Ji-Hyuk Park
ABSTRACTBackground:The mobile screening test system for screening mild cognitive impairment (mSTS-MCI) was developed for clinical use. However, the clinical usefulness of mSTS-MCI to detect elderly with MCI from those who are cognitively healthy has yet to be validated. Moreover, the comparability between this system and traditional screening tests for MCI has not been evaluated. OBJECTIVE: The purpose of this study was to examine the validity and reliability of the mSTS-MCI and confirm the cut-off scores to detect MCI...
June 20, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/29923070/a-systematic-review-and-meta-analysis-of-the-brief-cognitive-assessment-for-multiple-sclerosis-bicams
#3
REVIEW
Freya Corfield, Dawn Langdon
Multiple sclerosis (MS) is a neurological disease of the central nervous system which can lead to a range of severe physical disabilities. A large proportion of those affected will experience cognitive impairment, which is associated with a worse prognosis. Effective assessment of cognition in MS has been problematic due to a lack of suitable scales. The Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) was developed in 2010 as part of an international endeavour to facilitate cognitive assessment...
June 19, 2018: Neurology and Therapy
https://www.readbyqxmd.com/read/29920928/care-complexity-individual-factors-associated-with-hospital-readmission-a-retrospective-cohort-study
#4
Jordi Adamuz, Maribel González-Samartino, Emilio Jiménez-Martínez, Marta Tapia-Pérez, María-Magdalena López-Jiménez, María-José Ruiz-Martínez, Hugo Rodríguez-Fernández, Pilar Delgado-Hito, Maria-Eulàlia Juvé-Udina
PURPOSE: To determine the frequency of care complexity individual factors documented in the nursing assessment and to identify the risk factors associated with hospital readmission within 30 days of hospital discharge. DESIGN: Observational analysis of a retrospective cohort at a 700-bed university hospital in Barcelona, Spain. A total of 16,925 adult patient admissions to a ward or intermediate care units were evaluated from January to December 2016. Most patients were admitted due to cardiocirculatory and respiratory disorders (29...
June 19, 2018: Journal of Nursing Scholarship
https://www.readbyqxmd.com/read/29920330/dna-binding-protein-hmgb1-secreted-by-activated-microglia-promotes-the-apoptosis-of-hippocampal-neurons-in-diabetes-complicated-with-osa
#5
Yu Shi, Xiangyu Guo, Jie Zhang, Hanchi Zhou, Bei Sun, Jing Feng
Type 2 diabetes mellitus (T2DM) complicated with obstructive sleep apnea (OSA) may cause neuronal apoptosis and cognitive deficits, but the underlying mechanisms remain unclear. We aimed to determine the relationship between the activation of microglia and the apoptosis of hippocampal neurons, specifically in terms of high mobility group box-1 (HMGB1), after high glucose (HG) and intermittent hypoxia (IH) exposure. Diabetic KK-Ay mice and non-diabetic C57BL/6J mice (C57 mice) underwent IH or normoxia (control) exposure for 4 weeks...
June 16, 2018: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/29917225/psychological-treatments-for-adults-and-children-with-epilepsy-evidence-based-recommendations-by-the-international-league-against-epilepsy-psychology-task-force
#6
Rosa Michaelis, Venus Tang, Laura H Goldstein, Markus Reuber, William Curt LaFrance, Tobias Lundgren, Avani C Modi, Janelle L Wagner
Given the significant impact that psychosocial factors and epilepsy treatments can have on the health-related quality of life (HRQOL) of individuals with epilepsy and their families, there is great clinical interest in the role of psychological evaluation and treatments to improve HRQOL and comorbidities. Therefore, the International League Against Epilepsy (ILAE) charged the Psychology Task Force with the development of recommendations for clinical care based on evaluation of the evidence from their recent Cochrane review of psychological treatments in individuals with epilepsy...
June 19, 2018: Epilepsia
https://www.readbyqxmd.com/read/29915949/dietary-supplements-and-fatigue-in-patients-with-breast-cancer-a-systematic-review
#7
REVIEW
Paula Tâmara Vieira Teixeira Pereira, Andréa Dias Reis, Renata Rodrigues Diniz, Franciléia Andrade Lima, Richard Diego Leite, Mayara Cristina Pinto da Silva, Rosane Nassar Meireles Guerra, Érica Brandão de Moraes Vieira, João Batista Santos Garcia
PURPOSE: Cancer-related fatigue (CRF) is defined as a distressing, persistent, and subjective sense of physical or emotional and/or cognitive exhaustion. The treatment of CRF includes pharmacological and non-pharmacological therapies; dietary strategies with promising results have also been used. This study aimed to identify dietary supplements that improve fatigue in patients with breast cancer. METHODS: A systematic review of the literature was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement...
June 18, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29915582/imbalance-of-circulating-t-h-17-and-regulatory-t-cells-in-alzheimer-s-disease-a-case-control-study
#8
Timo Jan Oberstein, Lava Taha, Philipp Spitzer, Janina Hellstern, Martin Herrmann, Johannes Kornhuber, Juan Manuel Maler
The neuropathological hallmarks of Alzheimer's disease (AD), i.e., neuritic plaques and neurofibrillary tangles, consist of beta amyloid peptides (Aβ) and hyperphosphorylated Tau. These are accompanied by reactive microglia and astrocytes in the vicinity of the neuritic plaques and by changes to the peripheral immune system, e.g., an increase of the pro-inflammatory cytokines IL-1β, IL-6, and TNF-α in the peripheral blood. To address a potential involvement of peripheral T helper cell (Th ) subsets in AD, we conducted a case control study with 54 individuals with AD dementia ( n  = 14), with mild cognitive impairment (MCI) due to AD (MCIAD , n  = 14), with MCI unlikely due to AD (MCIother , n  = 13), and controls without cognitive impairment (controls, n  = 13)...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29914023/amyloid-mediated-cholinergic-dysfunction-in-motor-impairment-related-to-alzheimer-s-disease
#9
Tommaso Schirinzi, Francesco Di Lorenzo, Giulia Maria Sancesario, Giulia Di Lazzaro, Viviana Ponzo, Antonio Pisani, Nicola Biagio Mercuri, Giacomo Koch, Alessandro Martorana
BACKGROUND: Although motor disturbances parallel the course of dementia, worsening both quality of life and social costs, the pathogenesis remains still unclear. OBJECTIVE: Through the combination of cerebrospinal fluid (CSF) biomarkers assessment and transcranial magnetic stimulation (TMS) protocols, here we provided a cross-sectional study to understand pathogenic mechanisms of Alzheimer's disease (AD)-related early motor disturbances. METHODS: The motor phenotype, as defined with Unified Parkinson's Disease Rating Scale (UPDRS) part 2-3, Rating Scale for Gait Evaluation in Cognitive Deterioration (RSEGCD) and Tinetti scale, together with CSF profile of amyloid-β 42 (Aβ42), total-tau, and phosphorylated-tau were determined in 37 AD patients and compared to 18 patients with vascular dementia (VaD)...
June 8, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29913821/cognitive-modulation-of-experimental-pain-at-spinal-and-cortical-levels
#10
Mie Hviid Simonsen, Jakob Bredal Jensen, Ole Kæseler Andersen, Laura Petrini, Line Lindhardt Egsgaard, Carsten Dahl Mørch
Background/aims Descending modulation of the nociceptive system has proven to be pronounced in healthy humans. The descending modulation can be activated by rather distinct methods such as strong tonic painful stimulation or changes in the cognitive state. The extent of descending modulation on spinal pain processing remains unclear. Therefore, we assessed simultaneous cognitive modulation of spinal and cortical processing of experimental pain. Methods Painful (1.7 × pain threshold (PT)) and non-painful (0...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913743/somatocognitive-therapy-in-the-management-of-chronic-gynaecological-pain-a-review-of-the-historical-background-and-results-of-a-current-approach
#11
Gro Killi Haugstad, Unni Kirste, Siv Leganger, Elin Haakonsen, Tor S Haugstad
Historic background and development of our somatocognitive approach Mensendieck physiotherapy of the Oslo School is a tradition of physiotherapy founded by the American physician Bess Mensendieck, a contemporary and fellow student of Sigmund Freud at the Paris School of Neurology. It builds on the principles of functional anatomy and the theories of motor learning. We have further developed the theory and practice from this physiotherapy tradition, challenged by the enormous load of patients with longstanding, incapacitating pain on western health care systems, by seeking to incorporate inspirational ideas from body oriented dynamic psychotherapy and cognitive psychotherapy...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913734/understanding-the-link-between-depression-and-pain
#12
Steven J Linton, Sofia Bergbom
Background and aims Patients seeking care for a pain problem very often also report symptoms of depression.In fact, depression is associated with the development of chronic pain as well as poor treatment results. Yet, the mechanisms by which depression and pain impact upon one another are not clear. This paper provides a critical review of the literature with the aim of shedding light on the relationship between pain and depression. Further, we introduce the Örebro Behavioral Emotion Regulation Model which may stimulate understanding in addition to research...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913733/psychophysiological-responses-to-pain-stimulation-and-cognitive-tasks-in-female-temporomandibular-disorder-patients
#13
Christine Mohn, Olav Vassend, Stein Knardahl
Background and purpose Psychophysiological factors may contribute to the development of temporomandibular disorders (TMD). Both local orofacial and systemic responses have been investigated. However, most studies have concentrated on physiological responding during cognitive challenges, while responses during painful tasks may be highly relevant for the development of chronic pain conditions. Moreover, the relationship between experimental challenges and physiological responding may be influenced by affective responses during the experimental tasks, an issue not often considered in the literature...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29911970/large-scale-network-integration-in-the-human-brain-tracks-temporal-fluctuations-in-memory-encoding-performance
#14
Ruedeerat Keerativittayayut, Ryuta Aoki, Mitra Taghizadeh Sarabi, Koji Jimura, Kiyoshi Nakahara
Although activation/deactivation of specific brain regions have been shown to be predictive of successful memory encoding, the relationship between time-varying large-scale brain networks and fluctuations of memory encoding performance remains unclear. Here we investigated time-varying functional connectivity patterns across the human brain in periods of 30-40 s, which have recently been implicated in various cognitive functions. During functional magnetic resonance imaging, participants performed a memory encoding task, and their performance was assessed with a subsequent surprise memory test...
June 18, 2018: ELife
https://www.readbyqxmd.com/read/29909483/understanding-patient-reported-outcome-measures-in-huntington-disease-at-what-point-is-cognitive-impairment-related-to-poor-measurement-reliability
#15
N E Carlozzi, S Schilling, A L Kratz, J S Paulsen, S Frank, J C Stout
PURPOSE: Symptom progression in Huntington disease (HD) is associated with cognitive decline which may interfere with the self-report of symptoms. Unfortunately, data to support or refute the psychometric reliability of patient-reported outcomes (PROs) as HD progresses are limited. This is problematic given that PROs are increasingly recognized as important measures of efficacy for new treatments. METHODS: We examined PRO data from the HDQLIFE Measurement System (Speech Difficulties; Swallowing Difficulties; Chorea) in 509 individuals with premanifest, early-stage, or late-stage HD...
June 16, 2018: Quality of Life Research
https://www.readbyqxmd.com/read/29909057/study-design-and-protocol-for-a-culturally-adapted-cognitive-behavioral-stress-and-self-management-intervention-for-localized-prostate-cancer-the-encuentros-de-salud-study
#16
Frank J Penedo, Michael H Antoni, Patricia I Moreno, Lara Traeger, Dolores Perdomo, Jason Dahn, Gregory E Miller, Steve Cole, Julian Orjuela, Edgar Pizarro, Betina Yanez
Almost 2.8 million men in the U.S. are living with prostate cancer (PC), accounting for 40% of all male cancer survivors. Men diagnosed with prostate cancer may experience chronic and debilitating treatment side effects, including sexual and urinary dysfunction, pain and fatigue. Side effects can be stressful and can also lead to poor psychosocial functioning. Prior trials reveal that group-based cognitive behavioral stress and self-management (CBSM) is effective in reducing stress and mitigating some of these symptoms, yet little is known about the effects of culturally-translated CBSM among Spanish-speaking men with PC...
June 14, 2018: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29908234/agmatine-attenuates-methamphetamine-induced-passive-avoidance-learning-and-memory-and-camkii-%C3%AE-gene-expression-deteriorations-in-hippocampus-of-rat
#17
Maryam Noorbakhshnia, Arsham Rashidkaboli, Mahnaz Pakatchian, Siamak Beheshti
Methamphetamine (METH) abuse is one the most worldwide problems with wide-ranging effects on the central nervous system (CNS). Chronic METH abuse can associate with cognitive abnormalities and neurodegenerative changes in the brain. Agmatine, a cationic polyamine, has been proposed as a neuromodulator that modulates many effects of abused drugs. The aim of this study was to determine if agmatine can decrease the impairment effect of METH on memory and hippocampal CaMKII-α gene expression, a gene that plays a major role in memory...
June 13, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29907639/t-type-calcium-channels-in-the-orbitofrontal-cortex-mediate-sensory-integration-as-measured-using-a-spontaneous-oddity-task-in-rats
#18
Wendie N Marks, Madeline E Parker, Nadine K Zabder, Quentin Greba, Terrance P Snutch, John G Howland
The roles of low-voltage-activated (T-type) calcium channels in brain diseases have been studied extensively. Less is known regarding the involvement of T-type channels in cognition and behavior. Sensory integration (SI) is a cognitive process whereby the brain uses unimodal or multimodal sensory features to create a comprehensive representation of the environment. The multisensory object oddity (MSO) task assesses SI using combinations of sensory features of objects, either in the same or different sensory modalities...
July 2018: Learning & Memory
https://www.readbyqxmd.com/read/29906207/human-performance-deterioration-due-to-prolonged-wakefulness-can-be-accurately-detected-using-time-varying-spectral-analysis-of-electrodermal-activity
#19
Hugo F Posada-Quintero, Jeffrey B Bolkhovsky, Michael Qin, Ki H Chon
OBJECTIVE: The aim was to determine if indices of the autonomic nervous system (ANS), derived from the electrodermal activity (EDA) and electrocardiogram (ECG), could be used to detect deterioration in human cognitive performance on healthy participants during 24-hour sleep deprivation. BACKGROUND: The ANS is highly sensitive to sleep deprivation. METHODS: Twenty-five participants performed a desktop-computer-based version of the psychomotor vigilance task (PVT) every 2 hours...
June 1, 2018: Human Factors
https://www.readbyqxmd.com/read/29903787/quality-of-health-literacy-instruments-used-in-children-and-adolescents-a-systematic-review
#20
Shuaijun Guo, Rebecca Armstrong, Elizabeth Waters, Thirunavukkarasu Sathish, Sheikh M Alif, Geoffrey R Browne, Xiaoming Yu
OBJECTIVE: Improving health literacy at an early age is crucial to personal health and development. Although health literacy in children and adolescents has gained momentum in the past decade, it remains an under-researched area, particularly health literacy measurement. This study aimed to examine the quality of health literacy instruments used in children and adolescents and to identify the best instrument for field use. DESIGN: Systematic review. SETTING: A wide range of settings including schools, clinics and communities...
June 14, 2018: BMJ Open
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